Experts have compiled a list of the most harmful drugs for the liver. Unpleasant side effects of taking birth control pills
Many people consider medicines a panacea for all diseases. But doctors do not advise self-medication and start taking any medications without first consulting with specialists. Almost any drug, if taken incorrectly, can lead to overdose and even death. But sometimes even prescription drugs lead to sad consequences. This is due to the fact that people, in the hope of recovering faster, do not adhere to the prescribed dose, but significantly exceed it. Doctors secrete deadly drugs, from excessive intake of which most often a fatal outcome occurs.
How to take medicines correctly
With age, all organs and systems in the body begin to work intermittently, so sometimes they need to be helped with medicines. The most frequently affected digestive system, nervous and cardiovascular. Now it becomes clear why people old age early in the morning they rush not so much to have breakfast as to drink the next portion of medicines. In some cases, the number of tablets taken by the elderly is in the tens.
Almost all old people have a significant problem, they often forget whether they drank medicines, and if they drank, then when and in what quantity. Memory lapses can play bad joke with a person when he takes drugs for heart, headache or pancreatitis several times in a row. Such forgetfulness can end very badly.
There are dangerous drugs for life, so that their treatment does not bring harm, you should follow certain rules:
- It is necessary to maintain a special schedule for taking medications, even in young age. This will help not to get confused if the treatment regimen is quite complex and consists of several drugs.
- It must be remembered that lethal dose medicines is individual for each person If a couple of pills does not harm one patient, then another will bring a lot of unpleasant minutes.
- A lethal outcome from an overdose can also occur from taking only one or two tablets, in the event that there are chronic diseases of the heart, liver or kidneys.
- You can increase the dosage of the drug only on the advice of a doctor.
In no case should you self-medicate, based on the experience of a neighbor or friend. This approach to your health can cause a lot of unpleasant consequences, which will have to be treated for a long time.
Danger of heart drugs
To the first group dangerous means include glycosides, which are prescribed to patients with a large load on the heart. This group of drugs is of natural origin, they are prescribed for severe heart failure. Glycosides have positive impact throughout the cardiovascular system
- Improves blood circulation.
- Improves contraction of the heart muscle.
- The heart rate decreases.
- Characterized by an unexpressed diuretic effect.
These drugs have a therapeutic effect on the body only with the right dose and if there is no pronounced heart rhythm disturbance.
The life-threatening dose of such drugs (glycosides) should exceed therapeutic dosage ten times. A lethal outcome is also possible with a smaller volume of medication, in the event that ventricular tachycardia is observed.
With an overdose of glycosides in humans, such health disorders begin:
- Nausea, gagging, persistent diarrhea and cramping abdominal pain.
- Migraine, dizziness, loss of coordination and hallucinations.
- Convulsions are observed, arterial pressure decreases, breathing is persistently disturbed.
- If you make a cardiogram, you can see violations of the heart.
If a person greatly exceeds the dosage of heart drugs, he may have respiratory arrest and, as a result, death.
You can start taking any heart medications only after consulting a doctor and passing all the tests.
Sleeping pills
Another life-threatening pill is sleeping pills. If the dosage is incorrectly calculated, it is possible death. Most often, patients themselves are to blame for the overdose, since the pills do not act too quickly, and the hand reaches for an additional portion of the drug.
If the dosage is exceeded many times, then not only respiratory paralysis occurs, but also inhibition of the kidneys, nervous system and hearts. The most dangerous pills for life are sleeping pills, especially if the therapeutic dose is exceeded or they are taken with alcohol. With an overdose of sleeping pills, the following symptoms are observed:
- Atypical drowsiness, apathy and hearing impairment.
- The pupils narrow, the eyelids swell, saliva is strongly secreted, the pulse slows down.
- Developing coma with inhibition of some reflexes - cough, swallowing, pupillary.
- If it comes deep coma, then the pupils, on the contrary, dilate, breathing and pulse slow down, the heartbeat becomes rapid.
- Edema appears, affected small vessels which is manifested by bruising.
- If the coma is prolonged, then renal failure and pulmonary edema develop.
The most commonly prescribed are barbiturates and benzodiazepines. Exceeding the dosage of these drugs by 10 times inevitably leads to painful death.
All medicines must be kept out of the reach of children.. Best of all in a special locker that is locked with a key.
The danger of drugs for the treatment of the nervous system
What other drugs can lead to lethal outcome? Tranquilizers and antipsychotics are two broad groups of drugs that are used in psychiatric practice. Patients who are treated with such medicines should be constantly under the supervision of a doctor and relatives..
The lethal dosage of these drugs is individual for each person and depends on the state of the central nervous system, the presence of chronic diseases internal organs And genetic features. Tranquilizers and antipsychotics are rapidly absorbed in the stomach, converted in the liver and quite for a long time excreted by the intestines and kidneys.
Symptoms for which an overdose can be suspected look like this:
- Weakness in the muscles, lethargy, atypical drowsiness, hearing impairment.
- Trembling of limbs and head, convulsions.
- Violation of the cardiovascular system.
- decline blood pressure.
- Pulmonary edema, collapse.
The drug thymonin, which is often prescribed for various neurological disorders, often causes severe poisoning. When prescribing this medication, it is necessary to carefully calculate the dose and constantly monitor the treatment.
What drugs are considered dangerous
Levomycetin is a life-threatening drug. The explanation for this is simple. This drug is the most inexpensive antibiotic a wide range an action that people often use even without a doctor's prescription.
Many people start taking chloramphenicol for diarrhea without a doctor's prescription. You should not do this if the diarrhea is caused by a virus, then the antibiotic will only aggravate the situation.
Pain medications such as analgin or indomethacin can lead to stomach bleeding. In case of an overdose of these medicines, severe liver damage is observed, which can lead to cirrhosis and death.
TO dangerous drugs include and vasoconstrictor drops in the nose, which many people drip for a long time to facilitate nasal breathing. At long-term use such drops and sprays constrict the vessels of the brain, which leads to dizziness and migraine, and in children there may be loss of consciousness, convulsions and a coma.
Vasoconstrictor nasal drops can be used for no more than 5 days and only in the dosage prescribed by the doctor.
To avoid an overdose of drugs, you should follow the recommendations of your doctor. In addition, before starting treatment, it is worth carefully studying the annotation to the medication. If there are contraindications, then it is better to stop taking the medicine and ask the doctor to adjust the treatment.
Signs of harmful drug-food interactions to watch out for. What are the harmful drugs and in what cases should be feared negative effects- we will tell below.
Why are drugs harmful and how do drugs affect certain foods in your body?
- Medications can affect appetite. They can increase or decrease appetite, affect the absorption of calories, vitamin balance and body weight. For example, some painkillers can bring you a couple of pounds. excess weight.
- Medications may interfere with absorption nutrients. For example, alcohol affects the body's ability to absorb essential nutrients. If you drink, then you need more of them, respectively. Cholesterol-lowering substances adversely affect absorption folic acid, iron and calcium. On the other hand, citrus juice improves the absorption of iron contained in food.
- Medications can interfere with nutrient metabolism. For example, anticonvulsants used for epilepsy can cause vitamin D and folic acid deficiency in the body. Diuretics can lead to potassium deficiency. Even a simple, almost universal aspirin can lower the body's (folic acid) levels and increase the urinary excretion of thiamine and vitamins C and K. Some drugs, such as birth control pills, can unexpectedly increase the level of certain nutrients (vitamin A, calcium, iron ) and lower levels of others (riboflavin, folic acid, and vitamin C).
How food can affect the effectiveness of drugs
- Food can speed up the absorption of drugs by the body. Food can increase or slow down the rate at which drugs are absorbed, thereby affecting their blood levels. Calcium found in dairy products, for example, slows down the absorption of the antibiotic tetracycline.
- food products may interfere with drug metabolism. For example, some carbonated fruit juices or soda dissolve drugs faster than they can be absorbed.
- Food products can neutralize the effect of drugs. For example, natural licorice (but not artificial) can drastically interfere with the action of some blood pressure medications, having the exact opposite effect.
Other possible interactions between medicines And nutrients
Sometimes a combination of two types of medicines can cause serious harm to your body. For example, most anti-shstamins and other drugs cause drowsiness. If you add alcohol, the urge to sleep can become overwhelming. Imagine the danger you are in when you mix these substances and get behind the wheel!
Likewise, some medicinal herbs that people take to feel better may interact with medications. For example, the herb ginkgo biloba, which some people take to improve memory, may react with comadine, which is meant to dissolve or prevent blockages in blood vessels. This combination can lead to severe bleeding in case of tissue damage. Similarly, this herb interacts with aspirin. St. John's wort, which is used for depression, may reduce effectiveness contraceptives.
This list is by no means exhaustive, but it includes a description of the most common problems that can occur literally every day. So be sure to consult your doctor, pharmacist and other specialists about any possible combinations medicines you are taking.
State of the art modern medicine helps prevent unwanted pregnancy. Competent use contraceptives guarantees a woman the right to have a child when she is ready for it.
| Type of contraception | pros | Minuses |
|---|---|---|
| Hormonal | Effective protection against unwanted pregnancy, reducing the risk of ectopic pregnancy, malignant neoplasms in the organs of the reproductive system, normalization of the cycle, improvement of the skin condition, prevention of infertility, can be taken constantly | Side effects, contraindications, does not protect against sexually transmitted infections, requires organization - medication should not be skipped |
| Reliability, single use | High concentration of hormones, a limited number of doses, the likelihood of complications and side effects | |
| Emergency non-hormonal | Ease of use, low cost | Insufficient efficiency |
For nulliparous women correctly selected contraceptive is not dangerous. Analyze harm and benefit birth control pills necessary, taking into account the characteristics of a particular drug. These medicines are accepted only after consulting a gynecologist-endocrinologist.
Action
Oral contraceptives (OCs) contain the main hormones that regulate the uterine cycle and a woman's ability to conceive a child. The composition is:
- combined (COC) - based on estradiol and progesterone;
- mini-pill - based on progesterone.
According to the concentration of hormones combined preparations there are:
- microdosed;
- low-dose;
- medium dosed;
- highly dosed.
Depending on the content of hormones, OK is divided into:
- on monophasic (the content of estradiol and progesterone in all tablets is the same);
- biphasic (tablets contain a constant amount of estradiol and a varying amount of progesterone depending on the day of the cycle);
- three-phase (the amount of estradiol and progesterone in tablets corresponds to the day of the menstrual cycle).
Advantages modern drugs in the absence of side effects (weight gain, neoplasms, body hair growth), which were observed in the first oral contraceptives. These drugs appeared in 1960 and contained a large number of female hormones.
latest generation hormonal pills"Mini-drank" is recommended for women after 35 years of age, who are contraindicated in estrogens. Their reception is allowed even to smoking patients. Bleeding between periods is not an indication for contraceptive withdrawal.
Small doses of hormones contained in OK have a therapeutic and preventive action:
- prevent development malignant tumors organs of the reproductive system, infertility;
- regulate the uterine cycle;
- facilitate premenstrual syndrome;
- filmed pain during menstruation;
- improve skin condition.
Contraceptive hormonal pills are prescribed to a woman in special conditions:
- in mini-pills;
- KOC are included in therapeutic measures after artificial termination of pregnancy or miscarriage;
- OK for violations uterine cycle, for the prevention of endometriosis (growth of the inner layer of the uterine wall), in the treatment of mastopathy.
What are the consequences of canceling
Earlier hormonal agents contraception suggested a mandatory break of several months every 3 years of admission. Modern OK can be taken for a long time, their cancellation affects the body in different ways.
Positive
Already in the first months after the cancellation of OK, a woman has the opportunity to become pregnant. During the reception hormonal drugs created in the body favorable conditions to conceive a child: the ovaries are rested, the uterus is prepared for bearing the fetus. Birth control pills do not pose a threat to the life of the unborn child. But if pregnancy occurs while taking a contraceptive, it must be immediately canceled.
Negative
In some episodes, with the abolition of hormonal pills, women cannot become pregnant. In this case, gynecologists recommend that the patient undergo an examination to exclude the presence of inflammation. infectious diseases, malignant neoplasms in the uterus. In the absence of pathologies, a woman can plan a pregnancy.
Sometimes, after the abolition of OK, women begin to have skin problems, mood swings, depression occur, and the uterine cycle fails. These phenomena are associated with the development of dependence on the reception. steroid hormones. Negative reactions develop only in the case of an incorrectly selected contraceptive, therefore, the choice is made by the doctor and regularly monitors the patient's condition. Dependence in the course of taking OK does not develop.
Contraindications
The benefits and harms of birth control pills can only be determined by a specialist. The doctor will choose best condition health, regularity of sexual life and other factors. Definitely OK will harm when the following pathologies:
- diseases of the liver, kidneys;
- hypertension;
- diabetes;
- thrombosis;
- ischemia of the heart;
- arthritis;
- lupus erythematosus.
At depressive disorders, migraines, varicose veins, PMS birth control pills can be taken under medical supervision.
oral hormonal contraceptives are reliable and safe method. They should be selected only by the attending physician. This will help to avoid negative consequences and provide reliable protection from unwanted pregnancy. OK are used as therapeutic and prophylactic agents.
IN Everyday life many things are harmful to health - polluted atmosphere, water, radiation, stress and much more. But, today we will make a black list of pharmaceuticals and products, which we ourselves can influence by eliminating or reducing the amount taken orally harmful substances.
Blacklist published by the Ministry of Health:
Phenacetin
Cimetidine - Forbidden medical application
Hemodez- Prohibited medical use
Phenylbutazone(butadione)
Gentamicin– Limited medical use
- limiting the age of children who are prescribed these drugs to 3 years. For children under 3 years of age, gentamicin is prescribed exclusively for vital signs at a dose of 6.0-7.5 mg / kg per day, 2.0-2.5 mg / kg every 8 hours;
- the section "Contraindications" was added: "Severe disorders of the kidneys and hearing aid, hypersensitivity microorganisms to gentamicin or other aminoglycoside antibiotics”;
- caution and monitoring of kidney function and hearing during the use of gentamicin were noted: “When long-term use the dose of the drug should be such that would ensure the concentration of gentamicin in the blood, which does not exceed the maximum allowable (12 mg / mol), for which it is necessary to control it in the patient's blood;
- in the section “Peculiarities of use”, attention is drawn to the fact that ototoxicity increases with dehydration in the elderly and old age, and therefore it is necessary that the patient receive enough liquids. In case of development of resistance, the antibiotic should be discontinued and another adequate therapy prescribed.
Nitrofural (Furacilin) - Prohibited medical use of tablet forms orally
Nitrofuran– Limited medical use
Preparations containing coffee-coffee,- Prohibited medical use
Detox solutions which contain low molecular weight polyvinylpyralidone - Limited medical use
Metamizole sodium (analgin)– Limited medical use
- limiting the age of children when prescribing it in tablet form - up to 12 years;
- groups of patients with a possible risk of developing PR (with a burdened allergic history, blood diseases, impaired liver and kidney function);
- the duration of continuous use of these drugs is no more than 3 days for all age groups(in the middle therapeutic dose for adults 0.5 -1.0 grams);
Rofecoxib(rofika, denebol) - Limited medical use
- the maximum daily dose is limited (not higher than 50 mg per day)
- contraindication for use - people with increased risk from the cardiovascular system ( past heart attacks, strokes, progressive clinical forms atherosclerosis); age over 65 years.
Thioridazine(sonapax, ridazine) - Limited medical use
- the highest daily dose is limited (not higher than 300 mg per day)
- indication for use: limit mental states, psychoneurotic states, mental disorders of alcoholic origin
Eufilin– Prohibited medical use of medical forms that contain the stabilizer ethylenediamine
Nimesulide preparations– Limited medical use
- use in children under 12 years is prohibited;
- simultaneous application with potentially hepatotoxic agents
- alcoholism, drug addiction
- elevated body temperature and flu-like condition
Preprati Oseltamivir (Tamiflu) - Changes have been made to the Instructions regarding the potential risk of neurodevelopmental mental disorders against the background of the use of oseltamivir, especially in children.
Here listed a small fraction of what is really unhealthy. If you have comments on this list or know other harmful pharmaceuticals or foods, list them in the comments to the post. We will gladly add them to the general list.
Medicine is meant to heal people. But history knows cases when Aesculapius used substances that killed them to treat patients. In our review of 10 historically documented facts of the use of drugs, which in best case are placebos and, at worst, lethal poisons.
1. Paraffin
Today, doctors use Botox and collagen to rejuvenate facial skin. Also used silicone implants to increase breast size. But the story of wrinkle reduction and breast augmentation actually started much earlier than people think. The first documented attempts to remove wrinkles and artificial increase breasts were held as early as the beginning of the 20th century.
The procedure involved injecting paraffin directly into the area of wrinkles to smooth them out, or directly into the chest to increase its volume. But this practice quickly ended good reason. A side effect was infections that were introduced into the body during this primitive technique. Also similar procedures led to the formation of hard, painful lumps under the skin or in the chest.
Psychedelics such as lysergic acid diethylamide (LSD) and MDMA (ecstasy) have a long history of use as a treatment mental illness. Researchers in the 1950s and 1960s studied the use of LSD therapy. They have published numerous clinical papers and conducted experiments on over 40,000 patients. They faced the problem that the treatment of mental disorders with psychedelics could cause new mental disorders.
LSD can cause panic attacks or feelings of extreme anxiety. Thus, the condition of people diagnosed with schizophrenia or depression could worsen under LSD therapy. There have also been cases where LSD caused psychosis in people who were healthy before taking this drug. Not surprisingly, since 1970 psychoactive substances banned from being used as medical preparations.
In 1903 it was actively advertised radioactive water. After the discovery of radioactive radiation, dozens of manufacturers of "radioactive drugs" appeared, claiming that miracle drugs would cure everything from arthritis to hypertension. At the same time, side effects in the form of cancer, loss of hair and teeth, destruction of bones and rotting alive were usually silent.
4. Goat testicles
In the early 1900s, John Brinkley became one of the richest doctors in America, despite not even having medical education. He claimed to be able to cure impotence, infertility and other sexual problems surgically, namely, the implantation of goat testicles in the scrotum of a man. Not only did the operation have no justification, it was extremely dangerous.
In 1913, Brinkley opened a clinic where he began performing countless implant surgeries. The procedure cost $ 8,600 at the current value of the dollar. Not surprisingly, such an operation actually caused impotence and led to hormonal problems. Dozens of patients have died and hundreds have suffered from infection.
5. Arsenic
Arsenic is a fairly well-known poison, but it has been used as a medicine for centuries. In the traditional Chinese medicine, arsenic is known as "Pi Shuang". Arsenic was also a key ingredient in many patent medicines, including Fowler's Solution, a cure for malaria and syphilis that was used from the late 18th century until the 1950s. Another proprietary drug containing arsenic has been used to treat arthritis and diabetes. Women in Victorian era used arsenic as a cosmetic. All such procedures, of course, led to arsenic poisoning.
6. Manure
IN Ancient Egypt crocodile dung was used as a contraceptive. Dried manure was injected into the vagina. The idea was that, under the influence of body temperature, the manure softened and formed an impenetrable barrier. In addition to the Egyptians, some African cultures used elephant dung as a contraceptive.
In 17th century England, doctors advised chicken manure as a cure for baldness. In India, cosmetics and potions with the addition of cow dung were used to treat literally everything from cancer to acne. The problem with using manure as medicine is that there is always great amount bacteria, which in turn cause various diseases. Water pollution with faeces developing countries leads to 1.8 million deaths each year.
7. Mercury
Mercury was once a popular medicine and was used to treat syphilis, indigestion and a host of other ailments. Maybe the hypnotic fascination with the flowing silvery liquid has made it such a hot commodity. Mercury was taken by some powerful people, including Abraham Lincoln, whose fits of rage may have been due to the mercury content of the then-popular pills he took.
China's first emperor, Qin Shi Huang, is believed to have died from taking mercury pills, believing they would give him immortality. As soon as mercury enters the blood, you should immediately try to remove it. The neurotoxic elements found in mercury accumulate within just a few doses. Mercury poisoning can cause paralysis, insanity, loss of musculoskeletal function, neurological damage, and death.
3. Tapeworms
In the 19th century, diets became popular everywhere. In the early 1900s, tapeworm diets began to be advertised. Those who wanted to lose weight had to swallow a piece of beef containing worm larvae. It was believed that tapeworms would have reached maturity in the intestines and began to feed on the food ingested by humans.
This was supposed to lead to weight loss, as well as diarrhea and vomiting. After a person reached the desired weight, he took a pill that was supposed to kill tapeworms. Dead worms were excreted along with the feces, which often led to various complications. Also, tapeworms could grow up to 9 m in length, which could cause many diseases, including headache, vision problems, meningitis, epilepsy and dementia.
2. Intimacy with virgins
The myth that a person who suffers from sexually transmitted diseases can be cured by engaging in sexual intercourse with a virgin, appeared around the 16th century. Then in Europe they tried to treat syphilis and gonorrhea in a similar way. This myth is still prevalent in some African countries. Needless to say that similar treatment has the exact opposite effect.
In all medieval Europe and in the Middle East there have been cases where corpses were ground into powder and used as medicine. This "mummy powder" was considered a panacea for many common ailments such as headaches, coughs, and stomach ulcers. Ironically, it has also been used as an antidote for poisoning. In the 17th century, the French surgeon Ambrose Pere helped shake the confidence in healing properties mummies, stating that "this terrible drug does not bring any benefit, but on the contrary - causes severe pain in the abdomen, gives breath bad smell and induces vomiting.
They posed no less danger.
