Ibuprofen for pneumonia dosage. Interaction with other drugs

It is a non-steroidal anti-inflammatory drug with analgesic, anti-inflammatory, antipyretic and anti-edematous effects. Produced under the trademarks of various companies, the article will focus on the standard (not retard) tablet form of Ibuprofen.

Pharmacologically, it realizes its effects due to non-selective inhibition of COX-2, blocking the production of inflammatory cytokines.

Pharmacokinetically metabolized to form 3 metabolites, which are excreted by the kidneys. The maximum concentration is reached after 1 hour, the half-life is 2.5 hours, the retard forms can have a half-life of up to 12 hours.

Indications

The drug is indicated for:

• Inflammatory diseases of the joints, including osteoarthritis, gouty arthritis, rheumatoid arthritis and ankylosing spondylitis;
• Vertebrogenic pain syndromes;
• Moderate pain syndromes of various etiologies, such as headaches, myalgia, toothache, etc.;
• Feverish syndrome in infectious and so-called "cold" diseases.

Contraindications

There are contraindications to the appointment of Ibuprofen tablets:

• Signs of hypersensitivity to any of the ingredients of the drug. In addition, it is important before prescribing to identify hypersensitivity to acetylsalicylic acid and other NSAIDs in history, including data on attacks of rhinitis, bronchial obstruction and urticaria after taking NSAIDs, as well as complete / incomplete syndrome of acetylsalicylic acid intolerance (nasal polyps, bronchial asthma, rhinosinusitis) ;
• Inflammatory bowel pathologies;
• Erosive and ulcerative pathologies of the gastrointestinal tract in the acute stage, including Crohn's disease, ulcerative colitis and peptic ulcer of the stomach and duodenum;
• Blood clotting disorders, including hemophilia and hypocoagulation, as well as hemorrhagic diathesis;
• progressive kidney disease;
• Condition after coronary artery bypass grafting;
• Bleeding in the gastrointestinal tract, as well as intracranial hemorrhage;
• Pregnancy;
• Severe renal failure, confirmed hyperkalemia;
• Severe liver failure or active liver pathology;
• The patient's age is up to 6 years.

Should be used with caution when:

• The elderly age of the patient;
• Heart failure, arterial hypertension, ischemic heart disease and cerebrovascular pathologies;
• Dyslipidemia;
• Diabetes;
• Diseases of peripheral arteries;
• Smoking, alcoholism of the patient;
• Cirrhosis of the liver with portal hypertension;
• Hepatic and / or renal failure, if creatinine clearance is less than 60 ml / min, nephrotic syndrome;
• Hyperbilirubinemia;
• The presence of ulcerative pathologies of the stomach and duodenum 12 according to anamnestic information;
• H. Pylori infection, gastritis, colitis;
• Blood diseases of unclear etiology - anemia and leukopenia;
• During lactation;
• With prolonged use of NSAIDs;
• With severe somatic diseases;
• With the simultaneous use of oral corticosteroids, including prednisolone; antiplatelet agents, including acetylsalicylic acid, even in small doses, clopidogrel; anticoagulants, including warfarin; drugs from the SSRI group, including sertraline, paroxetine, fluoxetine.

Mode of application

Ibuprofen is prescribed to patients over 12 years of age orally in tablets of 200 mg 3-4 times a day. The dose can be increased to 400 mg three times a day (Table 2) to accelerate the therapeutic effect. When the effect is achieved, the dose of ibuprofen per day should be reduced to 600-800 mg. Ibuprofen is best taken after meals.

Attention, the maximum daily dose of the drug is 1200 mg - do not take more than six tablets of 200 mg in 24 hours! A second dose is taken no more than four hours later. Without consulting a doctor, taking the drug should not be longer than five days!

Do not apply to patients under 12 years of age without consulting a doctor!

When taking the drug for children from six to twelve, the following prescriptions should be observed:

• The maximum single dose is 1 tablet;
• Reception no more than 4 times a day;
• Admission is allowed only if the child weighs more than 20 kg!
• The interval between taking ibuprofen is at least six hours;
• The daily dose is not higher than 30 mg/kg.

Side effects

There are a number of possible side effects of Ibuprofen:

From the gastrointestinal tract: abdominal pain, nausea, heartburn, loss of appetite, flatulence, diarrhea, constipation, pancreatitis. Rarely, ulceration of the gastrointestinal mucosa, complications in the form of bleeding and perforations. Dryness and pain in the mouth, stomatitis, the appearance of aphthae and sores on the oral mucosa.
From the side of the liver: toxic hepatitis.
From the respiratory system: bronchospasm, shortness of breath.
From the sense organs: ringing in the ears, noise, hearing loss. Toxic damage to the optic nerve, impaired color perception, double vision, scotoma, dryness, eye irritation, swelling of the eyelids and conjunctiva.
From the side of the central nervous system: headaches, dizziness, anxiety, insomnia, drowsiness, hallucinations, depression. Rarely - aseptic meningitis (with a history of autoimmune pathologies).
From the CCC: tachycardia, heart failure, increased blood pressure.
From the urinary system: cystitis, polyuria, nephritis, nephrotic syndrome, acute renal failure.
Allergic reactions are possible: skin rash and itching, rhinitis, angioedema, anaphylactic reactions; dyspnea, fever, eosinophilia.
From the side of the hematopoietic organs: leukopenia, anemia, including aplastic, hemolytic; agranulocytosis, thrombocytopenia, thrombocytopenic purpura.
Other complications: the risk of bleeding - gingival, uterine, hemorrhoidal. Increased perspiration.

Possible changes in laboratory parameters:

• Increased bleeding time;
• Decrease in the concentration of glucose in the blood;
• Decreased creatinine clearance;
• Decreased Hb or hematocrit;
• Increasing the level of ALT, AST.

The risk of side effects increases in proportion to the duration of therapy.

Attention! If negative effects appear, you should stop taking ibuprofen and consult your doctor!

Overdose

Symptoms: nausea, vomiting, abdominal pain, lethargy, drowsiness, headache, depression, tinnitus, renal failure, metabolic acidosis, decreased blood pressure, coma, bradycardia, tachycardia, atrial fibrillation and subsequent respiratory arrest.

Treatment: active washing, sorbents, forced diuresis, symptomatic therapy.

special instructions

Treatment with ibuprofen should be carried out at the lowest effective dose for the shortest course possible. With long-term treatment, it is imperative to monitor the condition of the liver, kidneys, as well as the picture of peripheral blood. If the patient complains of nausea, vomiting and abdominal pain, it is imperative to conduct a thorough examination of the latter - conducting FGDS, OAC and a fecal blood test.

If the determination of 17-ketosteroids is required, then the drug should be canceled two days before the study.

Patients while taking the drug, it is advisable to refrain from any activity that requires increased concentration.

Storage conditions

Store in a dry place out of the reach of children at temp. not higher than 25°С. The shelf life is 3 years. Do not use expired products!

Analogues

With the active ingredient Ibuprofen, drugs such as Advil, Brufen, Artrocam, Bonifen, Burana, Ibuklin, Brustan, Deblok, Ibusan, Nurofen, and many others are produced. The drug is very common on the market and is used very often.

Price

Prices vary depending on the manufacturer.

The average price tag is:

• Packing of a tablet of 200 mg No. 20 17-400 rubles.
• Packing of a tablet of 200 mg No. 50 37-300 rubles. Prices for large packages have a lower upper threshold due to the fact that the original drug (Nurofen) is not produced in such packaging.

It is impossible to use NSAIDs uncontrollably. Consult a health care professional for advice, you should read the full instructions before use.

Of the group of non-steroidal anti-inflammatory drugs, Ibuprofen is considered one of the most popular. The medicine can be used not only as an antipyretic, but also as an anesthetic.

Ibuprofen is a propionic acid derivative. The drug has anti-inflammatory, analgesic and antipyretic effects. The analgesic effect is pronounced with pain against the background of the inflammatory process.

The active ingredient is ibuprofen. In addition, the composition of the drug includes: starch, magnesium carbonate, povidone, magnesium stearate, aerosil, vanillin, gelatin for pharmaceutical purposes, titanium dioxide, sucrose.

Absorption of the active substance occurs in the gastrointestinal tract. Higher concentrations are observed in the joints than in plasma. This is due to the fact that the substance slowly spreads through the joints, but lingers in the tissues. The drug is excreted through the kidneys within 24 hours.

After taking the drug, the therapeutic effect occurs within 30 minutes and lasts about 8 hours.

The drug is sold in various dosage forms: lozenges, syrup, rectal suppositories, granules, drops. For external use, Ibuprofen is available as a cream and gel 5%.

Ibuprofen syrup is usually prescribed for children, as this form makes it easier for the child to drink the medicine. In addition, the suspension has a strawberry and orange flavor, and the box also includes a measuring spoon.Tablets can not only be taken orally, but also dissolved in water, sucked.

Indications for use

For children, Ibuprofen is prescribed for febrile conditions against the background of acute respiratory viral infections, acute respiratory infections,. The drug can be used for oral or rectal use. After vaccination, many children have a fever, so the use of the drug is also necessary for prevention.

Ibuprofen can also be used to reduce pain from headaches, toothaches, migraines, earaches, and sprains.

For adults, Ibuprofen is indicated for inflammatory diseases:

• Rheumatoid arthritis.
• Psoriatic arthritis.
• Spondylosis.
• Bechterew's disease.
• Neck migraine.

The drug is taken for any pain syndrome, including postoperative.

As an adjuvant, Ibuprofen is used in the treatment of infectious and inflammatory pathologies of the ENT organs, adnexitis, panniculitis, inflammatory processes in the small pelvis.

Dosage and application rules

Adult ibuprofen can be taken by children from 12 years of age. For children from 6 months, a children's drug is produced with a dosage corresponding to this age. It is important to strictly follow the prescribed dosage by the doctor in order to avoid the development of possible adverse reactions.

For adults, the daily dose is divided into several doses, and per day it does not exceed 1200 mg. No more than 6 tablets should be taken per day. The interval between taking the drug should be at least 4 hours. If the pain is too severe, you can drink 2 tablets.

Ibuprofen tablets are taken 3-4 times a day, one tablet each. It is recommended to take the first tablet on an empty stomach, and the next - after a meal. This scheme increases the effectiveness of the drug and helps prevent unwanted side reactions.For children over 12 years of age, the dosage is calculated based on body weight: 20-40 mg per 1 kg per day.

Between each dose of the drug should pass at least 6 hours.

Reception of Ibuprofen for pain syndrome should not exceed 5 days, and for febrile conditions - 3 days. If the symptoms do not go away, then you need to see a doctor.

The dose of Ibuprofen as an antipyretic for children is calculated taking into account the degree of temperature increase:

• At a temperature of 38-39 degrees, the dose is 5 mg / kg.
• If the temperature is above 39 degrees, then the dosage is increased to 10 mg / kg per day.

The drug in the form of an ointment or gel is applied externally for 2-3 weeks. The agent is rubbed into the affected area 3-4 times a day.It is worth noting that Ibuprofen is not compatible with certain drugs, so it is best to use it only after being prescribed by a doctor.

Contraindications and side effects

Ibuprofen should not be taken if:

1. Hypersensitivity to individual components.
2. Violation of blood clotting.
3. Diseases of the gastrointestinal tract of an erosive-ulcerative nature.
4. Gastrointestinal bleeding.
5. Hemorrhages inside the skull.
6. Liver and kidney failure.
7. Pathology of the liver in the acute phase.
8. Hyperkalemia.

It is forbidden to use the drug for children under 6 years of age. For this age, the use of children's Ibuprofen is recommended.With caution, the drug should be taken by people suffering from hypertension, ischemia, peptic ulcer, gastritis, colitis, as well as heart failure, nephrotic syndrome.

If Ibuprofen is taken correctly, without exceeding the dosage, then no adverse reactions are observed. If the drug is taken incorrectly, side effects from the gastrointestinal tract are possible in the form of decreased appetite, diarrhea, heartburn, nausea, etc.Perhaps the appearance of shortness of breath, bronchospasm, increased blood pressure, dizziness, headache.

You can learn more about what non-steroidal anti-inflammatory drugs are from the video:

Children may experience allergic reactions in the form of skin rash, itching, allergic rhinitis. In rare cases, anaphylactic shock develops.

With an overdose, such symptoms appear. such as: nausea, vomiting, abdominal pain, headache, pressure drop, tachycardia, bradycardia, etc. In this case, it is necessary to wash the stomach, drink activated charcoal and drink plenty of alkaline drink. If necessary, symptomatic therapy is carried out.

Use in pregnancy

During pregnancy, the use of most drugs is strictly prohibited, due to the negative impact on the fetus. Ibuprofen is allowed to be taken during pregnancy if it proceeds normally.

In early pregnancy, the use of Ibuprofen as an antipyretic with increased tone can lead to miscarriage.

The use of the drug for pain in the lower part is strictly prohibited. In this case, you should call an ambulance.

The use of the drug should be only after prescription by a doctor. In the 3rd trimester, Ibuprofen should not be taken, since the active substance affects the early maturation of the placenta, as a result, this can lead to oxygen starvation and premature birth.

The dosage for women is 0.4 mg per day and strictly after meals.

Often, joint pain during pregnancy is associated with a lack of vitamins and increased stress. It is recommended to eliminate this unpleasant symptom without the use of medicines, but with the help of gymnastics, massage, taking vitamins, etc.

During breastfeeding, the drug is allowed, but at a minimum dosage. In any case, you should consult your doctor.

Analogues of Ibuprofen

Ibuprofen and similar drugs in terms of the active substance are characterized by high efficiency, rapid therapeutic effect, low sensitivity to the components in its composition. Thanks to these qualities, the drug is becoming increasingly popular.

Domestic analogues of Ibuprofen are characterized by low cost and the most common drugs in this group: Next, Ibuprofen for children.

The import analogues of Ibuprofen are the following drugs:

• Nurofen
• Brufen
• Ibuprom
• Faslik

These drugs have the same anti-inflammatory effect as Ibuprofen, but are more expensive.

Today, one of the most common diseases are ARVI, acute respiratory infections and the common cold. And although they are not given due attention, believing that everything will go away by itself, there must be treatment, because the body is not always able to cope with a cold lesion on its own. In the absence of adequate therapeutic influences, a number of serious complications can be earned. For example, if the treatment of SARS was inadequate, then this can lead to the development of pathological processes such as otitis media and sinusitis. These complications will require more protracted therapy. To avoid such consequences, the doctor, based on the diagnosis obtained, draws up an effective therapy regimen that will eliminate the common cold and at the same time not harm the body. Ibuprofen can be safely attributed to this drug. It is actively used in the treatment of flu and colds.

The benefits and effects of a good drug

Ibuprofen is a medical drug that belongs to the category of non-steroidal and anti-inflammatory drugs. It is a derivative of phenylpropionic acid. The medicine effectively stops the inflammatory process, relieves pain and reduces fever.

Ginger for colds and how to use it read.

Under the action of the presented component, the synthesis of prostaglandins is inhibited. These are biologically active substances that play one of the most important roles in the formation of the inflammatory process, pain and fever. The action of Ibuprofen is aimed at suppressing platelet aggregation.

Taking inside the drug in question, its active components are quickly introduced into the digestive tract. If you combine the medication with food, then the process of introducing its components slows down. Inactivation of the drug is observed in the liver, and excretion from the body occurs naturally.

The release of the drug can occur in various forms - tablets, ointment, gel, suppositories and suspensions. In the treatment of flu or colds, Ibuprofen is used in the form of tablets, suspensions and rectal suppositories. The latter option is used in the treatment of colds in young patients.

Read how to restore taste and smell with a cold.

With an incorrect dosage of the drug, side effects may occur, including:

• dizziness,
• bad dream,
• headache,
• excitation.

Sometimes treating a cold with ibuprofen can cause vomiting, nausea, heartburn, flatulence, diarrhea, and stomach pain. Adverse discharge may manifest as edema, skin rash and bronchospasm. With prolonged use of Ibuprofen, anemia, QoL bleeding, and impaired renal function may develop.

It is forbidden to take Ibuprofen with ulcers and gastritis in the acute stage, with impaired functioning of the optic nerve, hematopoietic organs, as well as with kidney and liver failure of a pronounced nature.

Pregnant patients should not treat colds or flu with ibuprofen while in the 3rd trimester of pregnancy. But the first and second trimester allows you to treat a cold with the drug in question. Also, Ibuprofen is not limited to nursing mothers.

But what vitamins with frequent colds in adults should be used in the first place, and by what parameters it is worth choosing them, this information will help to understand:

Indications

You can take Ibuprofen in the presence of the following pathological processes:

• inflammation of the joints of the spinal column;
• pain of different origin - toothache and headache;
• cold fever;
• as a symptomatic treatment of various pathologies.

How to take (instructions for use, how you can drink)

If therapy involves the use of a tablet preparation for children over 12 years of age and adults, then 200 ml should be consumed per day 4 times a day. You can get a quick and maximum result from therapy if you use the medicine at a time in the amount of 2 tablets. Use them 3 times a day. When positive dynamics is achieved, the dosage is reduced to the level of 600-800 mg. The first dose is taken in the morning on an empty stomach. This is how you can get the maximum healing effect. Subsequent administration of the drug is carried out after a meal. Az a day, use the medicine in an amount of not more than 1200 mg. This is the amount to drink in 24 hours. Also effective in the fight against colds and flu is Kagocel. Before use, we recommend that you familiarize yourself with.

The time interval between taking the medication will be 4 hours. The duration of treatment is determined only by the attending physician on an individual basis.

If you need to stop a sore throat with a cold, then adults and children over 12 years old should take Ibuprofen in tablet form used for resorption.

The daily dosage of the drug is 200-400 mg for 3 times.

Find out what to do if your ears are blocked with a cold.

As for the treatment of colds in young patients, it is worth giving Ibuprofen only in the form of a suspension for up to a year. Only a pediatrician who takes into account the condition of the baby can determine the dosage and duration of therapy. When using rectal suppositories, they must be installed 3 times a day. For children over 12 years old, you can take the drug in tablet format. When doing this, take into account that the weight of the patient is at least 20 kg. Between doses, observe a time interval of 6 hours.

Being in the 1st and 2nd trimester of pregnancy, you can take Ibuprofen only as directed by your doctor and only if the expected effect outweighs the possible risk to the fetus and mother.

Does ibuprofen help with colds and flu

As you know, Ibuprofen is able to relieve severe inflammation, have an antipyretic effect. Therefore, it can be prescribed in the treatment of colds and flu. But only to obtain a guaranteed result, it must be combined with other equally effective medicines.

Acting as a set, they will be able to stop the swelling of the mucous membrane, reduce pain in the throat, normalize the temperature, and improve well-being. Thus, it can be said that the treatment of colds from the use of Ibuprofen will be effective if it is combined with other anti-inflammatory drugs.

Video

This video will tell you about the features of the use (how to drink) of the drug Ibuprofen.

Ibuprofen (Ibuprofen) is a drug from the group of NSAIDs, NSAIDs (non-steroidal anti-inflammatory drugs, drugs).

Indications for the appointment of Ibuprofen are:

• Inflammatory and degenerative diseases of the spine and joints in rheumatism, rheumatoid arthritis, systemic lupus erythematosus, gout, ankylosing spondylitis, osteochondrosis;
• Other pathological conditions of an inflammatory, traumatic and metabolic nature, accompanied by pain in the joints (arthralgia), muscles (myalgia), bones (ossalgia), ligamentous apparatus;
• headache, migraine;
• Toothache;
• Menstrual disorders, painful cycle (algodysmenorrhea);
• Inflammation of the uterine appendages (adnexitis);
• Cold infections accompanied by fever;
• pathology of prematurity.

Ibuprofen is not effective for all pain. Intense pain syndrome in severe injuries, in the postoperative period, with cancer, with myocardial infarction - all this requires the use of stronger drugs, or a combination of Ibuprofen with these drugs.

In most cases, the elimination of inflammation, fever and pain under the influence of Ibuprofen is symptomatic without affecting the cause and course of the underlying pathology.

Employees of the Texas A&M University empirically found that Ibuprofen prolongs life.

During the experiment, nematode worms, yeast fungi, and flies were exposed to Ibuprofen at physiological doses for these organisms. At the same time, an increase in the life expectancy of prototypes by 10-17% was recorded.

In terms of a person, this increase is 10-12 years. What is the reason for the rejuvenating effect and slowing down of cellular aging under the action of Ibuprofen has not yet been established.

Active substance

The active substance is Ibuprofen, or alpha-methyl-4-(2-methylpropyl) benzoacetic acid.

Chemical formula - C 13 H 18 O 2.

It is a whitish crystalline powder, poorly soluble in water, and soluble in alcohol, acetone, and other organic solvents.

Ibuprofen is a derivative of propionic acid, an organic compound with the chemical formula C 2 H 5 -COOH, which belongs to saturated carboxylic acids.

Mechanism of action

Like other representatives of NSAIDs, Ibuprofen inhibits inflammatory reactions by influencing the synthesis of prostaglandins.

Prostaglandins are biologically active substances, the so-called. inflammatory mediators. They are synthesized almost everywhere, in all organs and tissues of the human body, under the action of the enzyme COX (cyclooxygenase).

The chemical raw material for prostaglandins is the polyunsaturated fatty arachidonic acid.

It is prostaglandins that trigger inflammatory reactions, manifested by fever, pain, swelling, redness of the skin.

At the tissue level, inflammation is manifested by damage (alteration), the appearance of pathological serous effusion (exudation), and excessive cell simple (proliferation).

Ibuprofen blocks COX, inhibits the synthesis of prostaglandins, and thus prevents the development of inflammation and the appearance of related symptoms.

It should be noted that in addition to the formation of the inflammatory process, prostaglandins perform many other functions. They maintain the mucous membrane of the stomach and intestines in proper condition, regulate local blood flow, prevent bronchospasm, and participate in metabolic reactions.

Prostaglandins are heterogeneous, and so is the COX, through which they are synthesized. COX-1 regulates the synthesis of "physiological" prostaglandins, and COX-2 - prostaglandins that form inflammatory reactions.

Ibuprofen belongs to non-selective NSAIDs - it inhibits both COX-1 and COX-2, while selective drugs inhibit only COX-2, and therefore they have almost no side effects.

As for non-selective NSAIDs, in particular, Ibuprofen, their side effects on the bronchi, liver, kidneys, gastrointestinal tract are associated precisely with the blocking of COX-1, and a decrease in the level of "physiological" prostaglandins.

In addition to prostaglandins, Ibuprofen inhibits the synthesis of thromboxane coagulation factor, other inflammatory mediators - bradykinin, leukotrienes.

By blocking COX, Ibuprofen inhibits the synthesis of prostaglandins, and thus prevents the development of inflammatory processes. It mainly acts on the phase of exudation and proliferation. The effectiveness of Ibuprofen, like other NSAIDs, is evaluated by anti-inflammatory, antipyretic and analgesic (pain) action.

The anti-inflammatory activity of Ibuprofen is relatively low. According to this characteristic, it is significantly inferior to many NSAIDs, incl. and propionic acid derivatives - Naproxen, Ketoprofen, and surpasses only Aspirin and Amidopyrine.

The analgesic and antipyretic effects of Ibuprofen are more pronounced. Although in this respect it is inferior to many NSAIDs. However, Ibuprofen does an excellent job in many cases and is widely used in clinical practice.

It has less side effects than many non-selective NSAIDs. Like other anti-inflammatory drugs, ibuprofen inhibits blood clotting by acting on the coagulation factor thromboxane.

In addition, inhibition of prostaglandin synthesis under the action of Ibuprofen is accompanied by a decrease in uterine tone and a decrease in intrauterine pressure. Not so long ago, the antiviral activity of Ibuprofen was noted. This drug stimulates the synthesis of intracellular interferon. In addition, Ibuprofen stimulates the closure of the ductus arteriosus when it is not closed in premature babies.

History of creation

The drug was synthesized in 1961 by employees of the research center of the British pharmaceutical company Boots. 12.01. In 1962 it was officially registered under the name Brufen by the British Patent Office.

Brufen was originally used to treat rheumatic diseases. A little later, in 1974, Ibuprofen under the name Motrin began to be actively used in the USA as an analgesic and antipyretic drug.

Since 1983, Ibuprofen under the name Nurofen has been approved for use without a prescription. And by 1985, it was taken by about 100 million people in many countries of the world.

For scientific achievements in the development of the drug Boots in the UK was awarded the Queen's Award. Currently, Ibuprofen is accepted in more than 120 countries, incl. and in Russia.

Production

The complex technologies for the industrial production of Ibuprofen are based on micronization (size reduction) of drug particles during the process of rapid expansion of a supercritical solution of liquid carbon dioxide.

Release form

• Tablets 200, 400 mg;
• Suspension for oral administration 100 ml containing 5 ml of 100 mg of the active substance;
• Ointment, gel 5%;
• Suppositories are rectal, containing 60 mg of the active substance.

This drug under a generic name is produced by many Russian and foreign (Denmark, Israel, Poland, Serbia, etc.) companies.

Of the drugs with commercial names, Nurofen is the most famous thanks to advertising. This drug in the form of tablets, capsules, suppositories, suspensions and gels is produced in England, the Netherlands and Spain.

No less famous Imet in the form of tablets is produced by the German Berlin-Chemie. The same company provides MIG tablets to the consumer market.

Another medicine, Faspik, tablets and granules for solution preparation, are the products of the Swiss branches of Zambon Pharma.

The German company Dolorgit produces Ibuprofen under the name Dolgit in the form of dosage forms for external use - cream and gel.

Another equally well-known company, Merkle, produces Ibuprofen in an injectable form called Pedea in the form of ampoules of 5 ml of a 2% solution. Sometimes in pharmacies you can find Finnish Buran tablets from the Orion company.

Ibuprofen is widely available in combined preparations. Among these drugs are Nurofen Plus tablets (with Codeine), Brustan, Ibuklin, Next tablets (with Paracetamol), and Deep Relief gel (with Menthol).

There are other commercial names for various dosage forms of Ibuprofen. Among them are Ibutard (a drug of prolonged action), Ibuprom, Ibufen, Ipren, Ibusan, Bonifen, Advil, and many others.

Among all NSAIDs, Ibuprofen ranks 3rd in terms of the number of drugs produced, second only to Aspirin and Paracetamol.

Since 2005, the volume of production of Ibuprofen has been steadily growing, increasing by 7.7% every year. Along with Ibuprofen, other NSAID propionic acid derivatives are also used in medical practice - Ketoprofen, Naproxen. But these are not synonyms, but analogues of Ibuprofen. Although these drugs have a similar effect to Ibuprofen, they have a different active substance.

Dosages

Adults and children over 12 years of age take ibuprofen 200 mg 3-4 times a day. Tablets are washed down with a glass of water. It is advisable to take them after meals.

If necessary, the daily dose of the drug in adults can be increased to 1200 mg. However, upon reaching a therapeutic effect, it is reduced to 600-800 mg.

Children under 12 years of age are allowed to take tablets if their body weight exceeds 20 kg. In these cases, 1 tablet of 200 mg is taken 4 times a day. The interval between taking the tablets should be 6 hours.

Suspension for oral administration is taken 3 times a day:

• Children from 3 months to 1 year: 50 mg (2.5 ml);
• Children 1-3 years: 100 mg (5 ml);
• Children 4-6 years old: 150 mg (7.5 ml);
• Children 7-9 years old: 200 mg (10 ml);
• Children 10-12 years: 300 mg (12.5 ml).

Suppositories for fever in children:

• From 3 to 9 months: 1 suppository 3 times a day every 6-8 hours
• From 9 months to 2 years: 1 suppository 4 times a day every 6-8 hours.

Gel and ointment: 2-4 g 2-4 times a day by smooth rubbing into problem areas.

Injectable ibuprofen (Pedea) in premature infants with non-closure of the aortic duct is injected into the umbilical vein 3 times - 1 time per day with a daily interval. The drug is used only in a hospital for its intended purpose and under the supervision of a physician. The dose is 5-10 mg/kg body weight of the newborn.

Pharmacodynamics

The drug is rapidly absorbed in the gastrointestinal tract. The maximum concentration is created in the blood after 1-2 hours, in the synovial fluid - a little later, but also lasts longer.

Eating slows down the absorption of Ibuprofen, but does not affect the amount of absorbed drug. In the blood, 90% of Ibuprofen binds to plasma proteins. Most of it undergoes metabolic transformations in the liver.

Analgesic and antipyretic effects persist for 8 hours after internal administration. 1% of Ibuprofen is excreted unchanged in the urine by the kidneys, the rest - in the form of metabolites by the kidneys (70%) and the liver (20%). The half-life is 2-2.5 hours.

Side effects

• gastrointestinal tract : nausea, vomiting, anorexia, abdominal pain, flatulence, diarrhea, ulceration in the stomach and duodenum, abnormal liver function;
• Respiratory organs: bronchospasm;
• CNS : headache, dizziness, general weakness, insomnia;
• Vision : decreased visual acuity, narrowing of the visual fields, swelling of the eyelids, eye irritation;
• L OR bodies : hearing loss, tinnitus, rhinitis;
• Leather : allergic reactions in the form of redness, urticaria, itching, angioedema;
• The cardiovascular system : palpitations, allergic anaphylactic shock;
• Blood : hemolysis of erythrocytes, leukopenia, thrombocytopenia, the threat of gastrointestinal and uterine bleeding;
• Urination : impaired renal function.

Contraindications

• Ibuprofen intolerance;
• Peptic ulcer of the stomach and duodenum;
• Other inflammatory diseases of the gastrointestinal tract, accompanied by ulceration of the mucous membranes and bleeding;
• Aspirin triad: bronchial asthma, nasal polyposis, intolerance to acetylsalicylic acid;
• Any conditions accompanied by hypocoagulation (slowing down of blood clotting);
• Optic neuritis, retinal damage;
• Vestibular disorders, hearing loss;
• Severe diseases of the liver and kidneys, kidney and liver failure.

In addition, taking the drug is not desirable when driving vehicles, or performing other activities that require targeted actions and concentration.

Pregnancy and lactation

The drug is contraindicated during pregnancy in the III trimester. During the I-II trimester, Ibuprofen is prescribed with extreme caution, given the ratio of the expected result and possible complications. When breastfeeding, the drug is contraindicated.

Interaction with other drugs

• Acetylsalicylic acid: anti-inflammatory activity decreases;
• Thrombolytics and anticoagulants: risk of bleeding;
• Cephalosporin antibiotics: the level of prothrombin in the blood decreases;
• Preparations of gold: toxic effect on the kidneys;
• Glucocorticoids: increased side effects of these drugs;
• Antacids: reduce the absorption of ibuprofen;
• Insulin and hypoglycemic tablets: the effect of these drugs is enhanced;
• Ethyl alcohol, antidepressants, barbiturates: toxic liver damage.

Storage

Store in a dark dry place at a temperature not exceeding 25 0 C. Shelf life - 3 years.

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Ibuprofen - instructions for use, what pills help with and how to use for adults and children. Ibuprofen IBUPROFEN (tablets, ointment, syrup, gel and suspension for children) is an antipyretic, analgesic, anti-inflammatory drug. Indications for use - various inflammatory processes caused by exposure to inflammatory prostaglandins.

The composition of the drug includes two molecules that complement each other, blocking the negative modifications of arachidonic acid metabolites. The active substance of the drug is ibuprofen, a derivative of phenylpropionic acid. It has antipyretic, anti-inflammatory and analgesic effects. Terms of sale: no prescription. The article will consider more detailed information about the drug Ibuprofen, instructions for using the tablet, price, reviews, analogues of the drug.

Compound

Pink film-coated tablets, biconvex; two layers are visible in cross section. Ibuprofen - 200 and 400 mg.

• 10 pieces. - cellular contour packaging (2) - packs of cardboard;
• 10 pieces. - cellular contour packaging (5) - packs of cardboard;
• 10 pieces. - cellular contour packaging (10) - packs of cardboard;
• 50 pcs. - dark glass jars (1) - cardboard packs.

Ibuprofen: instructions for the use of the drug differ depending on its dosage form. Ibuprofen, tablets and gel, for example, have different frequency of use. The composition of Ibuprofen in the form of suppositories includes 60 mg. active substance, solid fat.

The composition of the tablets: ibuprofen (200 or 400 mg), potato starch, magnesium stearate, aerosil, vanillin, beeswax, edible gelatin, azorubine dye. magnesium hydroxycarbonate, wheat flour, low molecular weight povidone, sucrose, titanium dioxide.

In ointment and gel, the active substance is contained at a concentration of 50 mg / g, in suspension - at a concentration of 20 mg / ml.

Auxiliary components of the gel: ibuprofen (50 mg/g), ethanol, propylene glycol, dimexide, carbomer 940, triethanolamine, neroli and lavender oil, methyl parahydroxybenzoate, purified water.

Auxiliary components of the ointment: dimethyl sulfoxide, macrogol 400 and 1500.

Release form

Ibuprofen is produced in the form of tablets, suspensions and ointments.

• Ibuprofen tablets are round, smooth, biconvex white. Each tablet contains 200 mg. or 400 mg. active substance. Excipients - magnesium stearate, talc, lactose, potato starch, colloidal silicon dioxide, Povidone 25. 10, 20 and 100 pieces per pack. From what these pills help, read in the article. But the fact that they are in no way inferior in effect to their counterparts is for sure;
• Long-acting Ibuprofen film-coated tablets. Each tablet contains 800 mg of active ingredient. 7, 14 and 60 pieces per pack;
• Lozenges. Each tablet contains 200 mg. active substance;
• Prolonged action capsules. Each capsule contains 300 mg. active substance;
• Suspension Ibuprofen for oral administration is homogeneous, yellow, with an orange smell. 5 ml. suspension contains 100 mg. active substance. Produced in bottles of 100 ml., in a cardboard box with a measuring spoon;
• 5% cream and gel for external use.

Ibuprofen is most effective for inflammatory pain. By antipyretic action is quite close to acetylsalicylic acid. It inhibits platelet adhesion, improves microcirculation and reduces the intensity of inflammation. When applied externally, Ibuprofen in the form of an ointment has a strong analgesic effect, reducing flushing, morning stiffness and swelling.

Indications for use

Taking Ibuprofen tablets is indicated in the presence of symptoms of an inflammatory reaction in various pathologies, which include:

• Inflammatory pathology of the joints and spine with pain syndrome - arthritis of any origin, including infectious, arthrosis (degenerative-dystrophic pathology), osteochondrosis (degenerative lesion of the spine), autoimmune processes;
• Moderate pain syndrome of various origin and localization - migraine (paroxysmal headache), toothache, algomenorrhea (painful menstruation), post-traumatic or postoperative pain, neuralgia (aseptic inflammation of peripheral nerves), myalgia;
• Feverish syndrome against the background of infectious intoxication with fever and body aches, including ARVI (acute respiratory viral infection).

The use of Ibuprofen tablets does not affect the progression of the pathological process, their use primarily implies symptomatic therapy.

Symptomatic treatment:

• Tension headache and migraine;
• Painful menstruation;
• Rheumatoid arthritis, osteoarthritis;
• Pain in the back, lower back, sciatica;
• toothache;
• joint, muscle pain;
• Feverish conditions with colds, flu;
• Pain from ligament injury.

NSAIDs are intended for symptomatic therapy, reducing pain and inflammation at the time of use, do not affect the progression of the disease.

According to the instructions for use, the drug penetrates into the articular tissues slowly, but there its concentration is higher than in plasma. This explains the effectiveness of the drug in arthralgia. The drug is included in the list of essential medicines of the World Health Organization, its efficacy and safety has been studied and clinically tested.

Ibuprofen: instructions for use - tablets

Eliminating painful symptoms is easy if you know how Ibuprofen works and what these pills help best with. According to the instructions, Ibuprofen is taken orally after meals.

The daily dose of the drug depends on the disease:

• With osteoarthritis, algomenorrhea, psoriatic arthritis and ankylosing spondylitis, adults are prescribed 400-600 mg. 3-4 times a day;
• For rheumatoid arthritis, take an increased dose, 800 mg 3 times a day;
• For soft tissue injuries and sprains, Ibuprofen tablets of prolonged action are used - 1600-2400 mg. once a day, preferably at bedtime;
• With moderate pain syndrome take 1200 mg. per day;
• In case of febrile syndrome that occurs after immunization, 50 mg is used, if necessary, the reception can be repeated after 6 hours, but not more than 100 mg. per day.

In febrile conditions, children over 12 years of age to reduce body temperature, the dose of Ibuprofen is calculated:

• Above 39.2 degrees C - 10 mg. per 1 kg of weight per day;
• Below 39.2 degrees C - 5 mg per 1 kg. weight per day.

Ibuprofen: instructions for use of the drug and dose. Ibuprofen lozenges are used to treat ENT diseases by dissolving in the mouth under the tongue. Children over 12 years of age and adults are prescribed 200-400 mg. 2-3 times a day.

Suspension for oral administration is usually prescribed to children. The average single dose when taken 3 times a day is:

• From 1 to 3 years - 100 mg .;
• From 4 to 6 years - 150 mg .;
• From 7 to 9 years - 200 mg .;
• From 10 to 12 years - 300 mg.

Ibuprofen gel or cream is applied externally, applying and rubbing it until completely absorbed on the affected area 3-4 times a day. Treatment can be carried out within 2-3 weeks.

ibuprofen prescribed for adults and children over 12 years of age inside, in tablets of 200 mg. 3-4 times a day. To achieve a rapid therapeutic effect, the dose may be increased to 400 mg. (2 tablets) 3 times a day.

When the therapeutic effect is achieved, the daily dose of the drug is reduced to 600-800 mg. The morning dose is taken before meals with a sufficient amount of water (for faster absorption of the drug). The remaining doses are taken throughout the day after meals.

The maximum daily dose is 1200 mg.(do not take more than 6 tablets in 24 hours). Take a second dose no more than 4 hours later. The duration of the drug without consulting a doctor is no more than 5 days. Ibuprofen: instructions for use states that the drug begins to act within an hour: it is rapidly absorbed in the intestines.

Do not use in children under 12 years of age without medical advice. Children from 6 to 12 years old: 1 tablet no more than 4 times a day; the drug can only be used if the child weighs more than 20 kg.

The interval between taking the tablets is at least 6 hours (daily dose is not more than 30 mg / kg). Externally applied for 2-3 weeks.

Ibuprofen tablets are light pink or pink in color, round biconvex in shape and have a smooth surface. They are taken for diseases of an inflammatory nature associated with the joints and spine. These are arthritis, spondylitis, gouty forms and manifestations, spondyloarthritis, arthrosis, rheumatism.

Moderate pain, with different etiologies of origin. This includes headache, discomfort in the area of ​​​​the teeth, the state of neuralgia, myalgia, pain after operations that have been transferred.

Ibuprofen ointment-gel: indications and instructions for use

What helps ibuprofen ointment? Ibuprofen ointment is a non-steroidal drug intended for external use with analgesic, antipyretic action. The anti-inflammatory effect is associated with the termination of the energy supply of inflammatory processes, and the analgesic property is indicated by a decrease in the intensity of inflammation.

Ibuprofen ointment is a popular anti-inflammatory drug, but before you buy it, you need to know about its pharmacological properties, indications and side effects.

What helps ointment-gel: indications for use. According to the instructions for use, ibuprofen ointment is prescribed for degenerative and inflammatory pathologies of the musculoskeletal system. These include the following diseases:

• Bechterew's disease (ankylosing spondylitis);
• Spinal hernia;
• Rheumatoid, gouty, psoriatic arthritis;
• Sciatica, lumbago, bursitis, myalgia;
• Shoulder-shoulder periarthritis;
• Radiculitis, tendovaginitis, tendinitis;
• Osteochondrosis, osteoarthritis;
• Traumatic bruises, sprains, dislocations, bruises or torn ligaments, swelling without compromising the integrity of the joints.

Instructions for use of Ibuprofen ointment-gel and dosage. Ibuprofen ointment should be used externally. Before use, clean the site of application of the drug, then apply a small strip (5-10 cm) of ointment to the affected area, then rub with light massage movements until the drug is completely absorbed.

Judging by the reviews about the preparation of doctors, it is advisable to apply the ointment 3-4 times a day until complete recovery, but not more than 3 weeks. After the symptoms decrease, the frequency of application is reduced. Use the product only on intact skin, avoiding areas of open wounds. It is not necessary to apply an occlusive dressing on the joints after applying the ointment. Ibuprofen: instructions for use indicate that in injuries and chronic diseases of the musculoskeletal system, this drug is simply irreplaceable.

Ibuprofen syrup-suspension: instructions for use for children

Suspension-syrup Ibuprofen is one of the most popular drugs to reduce high body temperature or fight pain. Such a medicine is available in several forms, and the most popular in the treatment of children is a suspension, since it is easy to give even to infants.

Ibuprofen: instructions for use are designed so that parents can get all the necessary information. Not everyone knows how such a medication acts on the child's body, when it is prescribed and in what dosage it is used for children.

Instructions for use of the suspension for children:

Before each use, the medication must be shaken, since during storage its contents are divided into a liquid part and a sediment. The remedy should be given to the child after meals in a dosage that is determined by age:

• Children aged 3 to 6 months weighing more than 5 kg. syrup is given in a dose of 2.5 ml. (twice a day);
• Infants 6-12 months of age weighing less than 10 kg. the drug is given 3 or 4 times a day, 2.5 ml;
• For babies aged 1 to 3 years weighing 10 to 15 kg. a single dosage will be 5 ml. suspensions. It is given three times a day;
• A child of 3-6 years old, whose weight is from 16 to 20 kg., is prescribed a three-time medication of 7.5 ml;
• At the age of 6 to 9 years with a weight of 20-30 kg. a single volume of the drug is 10 ml. Suspension in this dose is given 3 times a day;
• A child of 9-12 years old with a weight of 30 to 40 kg is prescribed medication three times a day, 15 ml.

Contraindications

• Inflammatory bowel disease in the acute phase, incl. ulcerative colitis;
• liver failure or active liver disease;
• In the period after coronary artery bypass grafting;
• Hypersensitivity to any of the ingredients that make up the drug;
• Confirmed hyperkalemia;
• children's age: up to 6 years and from 6 to 12 years (weighing less than 20 kg.) - for 200 mg tablets; up to 12 years - for tablets 400 mg;
• Anamnestic data on an attack of bronchial obstruction, rhinitis, urticaria after taking acetylsalicylic acid or another non-steroidal anti-inflammatory drug (complete or incomplete acetylsalicylic acid intolerance syndrome - rhinosinusitis, urticaria, polyps of the nasal mucosa, bronchial asthma);
• Pregnancy (3rd trimester);
• Erosive and ulcerative changes in the mucous membrane of the stomach or duodenum, active gastrointestinal bleeding;
• Hemophilia and other blood clotting disorders (including hypocoagulation), hemorrhagic diathesis;
• Renal failure (CC less than 30 ml / min), progressive kidney disease.

Carefully: old age, congestive heart failure, cerebrovascular disease, arterial hypertension, coronary heart disease, dyslipidemia / hyperlipidemia, diabetes mellitus, peripheral arterial disease, nephrotic syndrome, CC less than 30-60 ml / min, hyperbilirubinemia.

Peptic ulcer of the stomach and duodenum (history), the presence of Helicobacter pylori infections, gastritis, enteritis, colitis, long-term use of NSAIDs, blood diseases of unknown etiology (leukopenia and anemia), pregnancy (I-II) trimester, lactation period, smoking, frequent drinking alcohol (alcoholism).

Severe medical illness, concomitant therapy with the following drugs: anticoagulants (eg, warfarin), antiplatelet agents (eg, acetylsalicylic acid; clopidogrel), oral glucocorticosteroids (eg, prednisolone), selective serotonin reuptake inhibitors (eg, citalopram, fluoxetine, paroxetine, sertraline) .

The active ingredient of the drug is a derivative of phenylpropionic acid - ibuprofen. The drug is produced in the form of tablets (200 and 400 mg each), prolonged-release capsules (300 mg each), as well as in the form of a suspension and syrup for children. In 5 ml. suspension present 100 mg. ibuprofen.

For topical use, rectal suppositories are produced, and for external application - gel and ointment (5%). Tablets are supplied in blisters (10 pcs.) and polymer bottles (50 pcs.). Ibuprofen is actively used in pediatrics, the suspension can be given to babies from 3 months of age. Many parents do not understand and ask the doctor " What can Ibuprofen tablets help young children with?» Typically, these pills are prescribed by a specialist to eliminate pain.

Side effects

1. From the sense organs: hearing impairment: hearing loss, ringing or noise in the ears; visual impairment: toxic damage to the optic nerve, blurred vision, scotoma, dryness and irritation of the eyes, swelling of the conjunctiva and eyelids (allergic genesis);
2. From the side of the hematopoietic organs: anemia (including hemolytic, aplastic), thrombocytopenia and thrombocytopenic purpura, agranulocytosis, leukopenia;
3. From the digestive system: NSAID gastropathy (abdominal pain, nausea, vomiting, heartburn, loss of appetite), diarrhea, flatulence, constipation; ulceration of the gastrointestinal mucosa, which in some cases is complicated by perforation and bleeding; irritation or dryness of the oral mucosa, pain in the mouth, ulceration of the mucous membrane of the gums, aphthous stomatitis, pancreatitis, hepatitis;
4. From the side of the central and peripheral nervous system: headache, dizziness, insomnia, anxiety, nervousness and irritability, psychomotor agitation, drowsiness, depression, confusion, hallucinations, aseptic meningitis (more often in patients with autoimmune diseases);
5. From the side of laboratory indicators: bleeding time (may increase), serum glucose concentration (may decrease), creatinine clearance (may decrease), hematocrit or hemoglobin (may decrease), serum creatinine concentration (may increase), liver transaminase activity (may increase);
6. From the respiratory system: shortness of breath, bronchospasm;
7. From the urinary system: acute renal failure, allergic nephritis, nephrotic syndrome (edema), polyuria, cystitis;
8. From the side of the cardiovascular system: heart failure, tachycardia, increased blood pressure;
9. allergic reactions: skin rash (usually erythematous or urticaria), pruritus, angioedema, anaphylactoid reactions, anaphylactic shock, bronchospasm or dyspnea, fever, erythema multiforme exudative (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome) , eosinophilia, allergic rhinitis;
10. Other: increased perspiration.

There are many modern drugs that allow you to quickly stop pain attacks. Like any NSAID, this medication demonstrates the qualities of an antiplatelet agent. There is evidence that its active substance is able to stimulate the production of a person's own interferon, thus improving the patient's nonspecific immunity.

To eliminate the pain syndrome, which can greatly spoil the quality of life due to its intensity, it would be reasonable to use non-steroidal anti-inflammatory drugs with an anesthetic effect.

Use during pregnancy and lactation

Ibuprofen is the drug of choice for pain and fever during pregnancy, since it is safer for a woman's body during this period of time than most other analgesics and antipyretics.

In the first 2 trimesters of pregnancy, it does not adversely affect the development of the fetus, does not provoke bleeding (unlike aspirin) and does not threaten miscarriage. In the last trimester of pregnancy, Ibuprofen is contraindicated.

First, the drug inhibits the contraction of the muscles of the uterus. Secondly, its use can cause the closure of the Botallian duct and the development of pulmonary hypertension in a child. Thirdly, the drug tends to block the hormones responsible for the birth process. Ibuprofen during breastfeeding does not affect the quality and secretion of milk, so it can be used to treat lactating women.

The forms in which this tool is offered in pharmacy chains are designed for children and adults. Reduces morning stiffness, increases the range of motion in the joints. When taken orally, ibuprofen is almost completely absorbed from the gastrointestinal tract. Simultaneous ingestion of food slows down the rate of absorption. Metabolized in the liver (90%). It is one of the derivatives of propionic acid. It belongs to the group of essential medicines.

special instructions

Ibuprofen: instructions for use of the drug description, composition, indications, contraindications, side effects, overdose. Treatment with the drug should be carried out in the minimum effective dose, the minimum possible short course. During long-term treatment, it is necessary to control the picture of peripheral blood and the functional state of the liver and kidneys.

When symptoms of gastropathy appear, careful monitoring is indicated, including esophagogastroduodenoscopy, complete blood count (hemoglobin determination), fecal occult blood analysis.

If it is necessary to determine 17-ketosteroids, the drug should be discontinued 48 hours before the study. Patients should refrain from all activities that require increased attention, rapid mental and motor reactions. Ibuprofen: instructions for use of tablets (ibuprofen) says - the drug can relieve the symptoms of any pain. During treatment, it is not recommended to take ethanol (alcohol).

The use of Ibuprofen tablets is justified for pathologies of the spine / joints, fever, monthly pain, toothache and headache, injuries of the musculoskeletal system and soft tissues. The medicine can be prescribed to treat the symptoms of influenza, gynecological, ENT diseases. Ibuprofen tablets help reduce / eliminate pain, swelling, in addition, they are an effective remedy for fever.

Analogues of the drug Ibuprofen

• Ibuprofen-Verte;
• Faspik;
• ArtroKam;
• Ibuprom;
• MIG 400;
• Nurofen Period;
• Brufen retard;
• Ibuprofen Nycomed;
• Children's Motrin;
• Burana;
• Nurofen Ultracap;
• Advil;
• Nurofen Express;
• Ibuprofen Lannacher;
• Bonifen;
• Nurofen for children;
• Ibuprofen-Hemofarm;
• Deblock;
• Ibutop gel;
• Nurofen;
• Ibuprom Max;
• Ibufen;
• MIG 200;
• Solpaflex;
• Pedea;
• Ibusan;
• Brufen;
• Nurofen forte;
• Ibuprom Sprint Caps;
• Long;
• Ipren.

Ibuprofen belongs to the group of non-steroidal anti-inflammatory drugs. The traditionally produced form is represented by coated tablets. Ibuprofen belongs to non-hormonal drugs that suppress inflammation.

The way the drug influences is explained by the suspension of the production of hormone-like substances that contribute to the development of an inflammatory reaction. Ibuprofen: The instructions for use say that this is a fairly safe drug and is usually well tolerated, as it is a hormone-free type of drug and an anti-inflammatory drug.

Application in childhood

Tablets 200 mg. do not prescribe to children under the age of 6 years and from 6 to 12 years (weighing less than 20 kg.); tablets 400 mg. - children under the age of 12.

Ibuprofen price

Name of the drug	Price
200 mg. #20 5% ointment 25 g. 200 mg. #50 400 mg. #20 200 mg. #50	16 rub. 25 rub. 27 rub. 35 rub. 38 rub.

Overdose

If the daily or single dose of Ibuprofen is exceeded, then the following manifestations occur:

• Acute renal failure;
• Pain in the abdomen, nausea, vomiting;
• headache, tinnitus;
• Metabolic acidosis (disturbance of the acid-base state, manifested by low blood pH and low concentration of bicarbonate in the blood);
• Atrial fibrillation and respiratory arrest;
• Coma;
• Lowering blood pressure;
• Lethargy, drowsiness, depression;
• Rapid or slow heartbeat.

For the following conditions, treatment is used:

• activated charcoal (used to reduce the absorption of the drug in the gastrointestinal tract);
• Symptomatic therapy (monitor blood pressure, heart rate and general condition);
• Gastric lavage (effective during the first hour after taking the medicine);
• Alkaline drinking and forced diuresis.

When the first measures are taken, it is necessary to seek qualified help and call an ambulance.

Ibuprofen reviews

1. Ibuprofen: instructions for use, contraindications, side effects, reviews. The drug "Ibuprofen" saves me from various pains throughout the year. Since I have back problems and periodically suffer from severe pain, the list of anti-inflammatory drugs in my first aid kit is impressive. Having become a mother for the second time, I had to limit my medication. But the constant carrying of the baby in her arms makes itself felt, and the back began to hurt more and more often. Sometimes there is simply no strength to endure this pain and you have to resort to the help of medicines. The approved anti-inflammatory and analgesic drug during breastfeeding is ibuprofen. There are, of course, more expensive analogues, but I trust our medicine. He helps me a lot. The main thing is to follow the indicated dosage. Time of use: more than a year. Cost: 25 rubles;
2. I'm sorry I only recently discovered Ibuprofen. Before that, I bought expensive analogues and was glad that the pills help well. In fact, ordinary domestic ibuprofen is the active ingredient of many well-known drugs - Nurofen, Ibufen, Imet. I remember how glad I was that I discovered Imet, an effective, fast-acting remedy. Okay, let's count: Tablets Imet, 10 pieces, dosage 400 mg. ibuprofen in one tablet - the price is 150 rubles. Nurofen tablets, 8 pieces, dosage 200 mg. ibuprofen in one tablet - the price is 100 rubles. Ibuprofen tablets, 20 pieces, dosage 200 mg. ibuprofen in one tablet - the price is 16 rubles.

   So how do you like math? To get the effect of Imet, you just need to drink two Ibuprofen tablets. On a note, I will say that Ibuprofen: instructions for use is one of the most popular drugs from the group of non-steroidal and anti-inflammatory drugs that have antipyretic and analgesic effects;

3. Ibuprofen tablets were prescribed to me by a traumatologist when my arm began to swell and for a long time he could not figure out what exactly was the matter and prescribed pills to reduce pain. What can I say, the tablets are sold both in plates and in packages, the price is not at all expensive. At first I took it only as an anesthetic for my hand, but now, if necessary, I always buy them for any spasms and pains. The tablet starts to act after 40 minutes, sometimes even earlier. The pain goes away completely, but unfortunately not for long, after a couple of hours you need to drink a second one. And after the first dose, side effects began, namely dizziness, but it passed quickly after 5 minutes and this did not happen again. In general, the pills are not bad and help very well;
4. Ibuprofen is the first remedy for colds and flu in our family. Excellent antipyretic, helps immediately. Eliminates the symptoms of a cold, alleviates the general condition. The drug is also used for rheumatism, headaches and toothaches, and migraines. Many analogues substitutes contain the active ingredient - ibuprofen, therefore, if you do not want to overpay for advertising, I advise you to buy Ibuprofen from Russian manufacturers. The effect is the same. Helped me with headaches. Literally after 15 minutes, I already felt like a full-fledged person. The pain did not return at the same time. We bring down the temperature of the whole family. The main thing at the same time, observe the dosage and not overdo it. There are not many contraindications, but there are. Stomach ulcer, heart failure, asthma, allergic reactions to the components of the drug. Can be taken in the first trimesters of pregnancy. Didn't experience any side effects. But, I didn’t abuse it, I strictly adhered to the instructions. I also didn’t hear negative reviews from my friends. In my opinion, one of the best antipyretic and analgesic drugs. In addition, it is inexpensive, given its wide range of activities. I bought the last time a pack of 20 tablets for 25 rubles. I wish everyone good health, and not get sick at all if possible;
5. My acquaintance with ibuprofen began with Nurofen (its main working substance is ibuprofen). After many tried painkillers, the effectiveness of which did not satisfy me, I settled on Nurofen for a while. Everything was great: it works quickly, for a long time and effectively. Only the price did not suit me. I decided to ask what analogues he has (Ibuprofen: instructions for use do not say anything about this), based on ibuprofen. There are many analogues, and most of them are kept in the same price category as nurofen. In addition to the simplest domestic Ibuprofen, which, by the way, costs ridiculous money - 22 rubles per package, in which 50 tablets. Ibuprofen: instructions for use say that the medicine is used orally, mainly between meals. Manufacturers can be different, they have only one thing in common - all domestic (I bought Ibuprofen from 3 manufacturers, there is no difference). It does not act as quickly as Nurofen, well, quite a bit slower, but it also anesthetizes for a long time and well. or toothache, moderate to severe back pain.)

Ibuprofen review. Reviews of ibuprofen. Nurofen analogue. What is ibuprofen for?