Poisoning with vasoconstrictor drops. Children's poisoning with vasoconstrictor drops Naphthyzine

According to Life, well-known pharmaceutical companies and Roszdravnadzor bombarded Russian pediatricians with warnings in 2016-2017. Their content is approximately the same: children are increasingly poisoned by vasoconstrictor drops. We are talking about naphthyzinum, sanorin, otrivine and other similar preparations. If you overdo it with treatment, the child may get heart problems or even fall into a coma. As Roszdravnadzor notes, many parents do not know this and therefore allow children to bury them uncontrollably. As a result, thousands of children across the country end up in hospitals every year.

At the beginning of 2017, one-year-old Seryozha from the city of Tchaikovsky, Perm Territory, caught a cold, and his mother, leaving for work, instructed her grandmother how to treat the baby. And although the boy sniffed, his mother did not leave any drops. The grandmother decided that this was not a problem, and dripped naphthyzinum to her grandson. She didn’t even drip, but, one might say, flooded it so as not to leave the snot a chance. That day Vanya fell asleep earlier than usual after dinner.

Grandma woke him up and dripped some more. After that, the child slept all day.

The mother, returning from work, could not wake her son. In a panic, she called an ambulance. The arriving brigade tried in every possible way to bring the child to his senses. With a pulse rate of about 110-120 beats per minute, Serezhin's heart beat at a speed of only 30 beats. The boy was pale, reacted only to strong painful stimuli. The hospital said: Naphthyzinum poisoning.

The doctors managed to save Seryozha, a day later he was already running around the department, and four days later he was discharged home. The fact that the boy almost died is not to blame for the drops, but for the adults who misused them.

How drops work

During the flu and colds, our nose is blocked from the fact that the mucous membrane in the sinuses swells and “swells”. To relieve swelling, millions of our compatriots use drops like naphthyzinum. They constrict the vessels of the mucosa, the edema subsides, and the nasal passages expand.

Sanorin, naphthyzine, xylene, rhinostop are drugs of the same pharmacological group, - explains pediatrician, candidate of medical sciences Tuyara Zakharova.

The problem is that with an overdose, not only the capillaries in the nose begin to narrow. The action extends to large vessels that carry blood to the kidneys, heart and brain. This is fraught with dangerous consequences: a person's pulse drops, blood pressure rises, signs of anemia appear. The body of an adult is able to "swallow" large doses of drops without serious consequences. But for children, an overdose is extremely dangerous. The worst thing that can happen is heart problems.

For example, sanorin is used only from the age of two, says Tuyara Zakharova. - This is due to the fact that in young children, even a small amount of the drug can cause spasm in the heart muscle.

drug poisoning

Roszdravnadzor sounded the alarm and from June 2016 to May 2017 sent 12 official letters to all regional medical institutions about the dangers of using vasoconstrictors. Their copies are at the disposal of Life. These documents are prescribed to be distributed in all pharmacies and pediatricians. The letters mention nine names of drops. This is almost the entire "vasoconstrictive" assortment of Russian pharmacies.

Analyzing information about the side effects [of vasoconstrictor drops and sprays], Roszdravnadzor specialists learned about a significant number of overdoses in pediatric practice, the department's documents say. - We have recorded a large number of acute and subacute drug poisoning in children under the age of 15 years [after using the drugs].

A source in the department told Life that they began to study the problem after reports from children's hospitals in the central region.

We received data from one of the children's hospitals. In their toxicology department, 892 children under the age of 15 were treated in two years due to poisoning [vasoconstrictor], a source told Life. - All poisonings were accidental and occurred due to excess dosages, as well as due to non-compliance with contraindications for age. However, the documents do not indicate how many children in Russia were poisoned by drops.

Life sent a request to Roszdravnadzor with a request for statistics, but has not yet received a response. The scale of the problem can also be assessed using the example of a particular Moscow hospital. Every year, due to improper treatment, only in the hospital. N.F. Filatov enrolls 250-300 children under the age of four.

In 2015, we received 244 children, and in 2016, 250 children were treated. Basically, in cases of poisoning, all liquid-type drugs and even household chemicals are recorded. For example, these are vasoconstrictor drops in the nose, ”Dmitry Dolginov, head of the toxicological department of the hospital, told Life.

Parents can recognize vasoconstrictor poisoning by several basic signs.

The main symptom of vasoconstrictor poisoning is changes in the nervous system. The child becomes restless or, conversely, inhibited, - Boris Blokhin, chief freelance pediatrician of the Moscow Health Department, told Life. - You can avoid poisoning if you strictly follow the recommendations written on the preparations. And to understand that any medicine is not only a treatment for a child, but also the possible development of side effects.

Life sent inquiries to large pharmaceutical companies in Russia and Germany that produce drops, asking them to comment on the situation. These are the Moscow Endocrine Plant, the German Bayer and Merkle GmbH. At the time of publication, only representatives of the Bayer company, which produces Nazol drops, responded.

To ensure the correct use of the drops, Bayer informed doctors and pharmacists about strict adherence to the dosing regimen, contraindications and precautions when using medicines, Svetlana Meleshko, a representative of the company, told Life. - Bayer carefully handles all information related to drug misuse, adverse events and overdoses and provides this information to regulatory authorities.

Pavel Kochegarov

With the usual runny nose and nasal congestion in children, not all parents consider it necessary to seek medical help. In the course are proven over the years and inexpensive drugs that have been treated for more than one generation. Among them, the most popular are naphthyzine drops. Meanwhile naphthyzinum poisoning in children is quite common. The situation of poisoning is aggravated by the fact that parents do not always associate the intake of naphthyzine with a deterioration in the child's well-being.

Consider how dangerous naphthyzine is, in what cases poisoning occurs and what to do if it does happen.

Causes of poisoning

Naphthyzinum belongs to vasoconstrictor drugs. It is effective in the treatment of rhinitis, pharyngitis, sinusitis, laryngitis and other diseases of the nasal cavity. The use of the drug eliminates swelling, constricts blood vessels, allows air to enter the nasal cavity and facilitate the child's breathing. Naphthyzine is effective in chronic conjunctivitis, allergies, nosebleeds. The composition of the drug includes the main component naphazoline and auxiliary ingredients: boric acid and distilled water.

With all the effectiveness of the drug, statistics inexorably testify to frequent poisoning in children. To answer the question of whether naphthyzine is harmful and how justified its use, it should be remembered that children are more sensitive to the action of this medication. Naphthyzine is prohibited for use in infants. When treating older children, the dosage must be strictly observed.

A well-known factor is that long-term use of the drug is addictive and a kind of dependence. Therefore, even adults are not recommended to take the drug for more than five days.

It is an erroneous opinion that poisoning occurs only in cases where the child drinks naphthyzine. With the usual intake, an overdose of naphthyzine leads to a rapid entry of the drug into the blood through the developed vascular system of the mucous membranes of the nasal cavity. This causes a general intoxication of the baby's body.

Thus, the following causes of naphthyzine poisoning in children can be distinguished:

1. Percentage of solution inappropriate for children's age. Often parents use a 0.1% solution. In adults, this dose does not cause side effects, but for a baby, it can become dangerous. The recommended solution for children is 0.05%. On the recommendation of a doctor, a 0.025% solution can be used. To obtain it, 0.05% agent is diluted with distilled water.
2. Uncontrolled use of the drug or its use for the treatment of children under the age of one year.
3. Insufficiently thought out form of release of the drug. Naphthyzine is produced in plastic vials, which does not always allow you to accurately measure the required number of drops.
4. OTC sale of the drug, the attitude of adults to the drug as to "innocent" drops.

The low price of the drug and its popularity are often the main factors in the choice of parents. Having decided to use naphthyzine, not all parents are aware of what the consequences of poisoning may be. Since naphthyzinum is characterized by a short action (approximately 4-6 hours), it requires frequent use. By dripping the drug into our child 4-6 times a day, parents, without even realizing it, bring the concentration of the active substance in the body of their baby to a dangerous point.

10 mg of naphthyzine can be fatal in children of the first two years of life!

In some cases, poisoning occurs when using an expired remedy. Parents should be very careful with the packaging and throw away the medicine immediately after its expiration date.

Symptoms

In case of poisoning with vasoconstrictor drugs, parents first of all pay attention to extreme weakness and lethargy in children. Most children fall asleep quickly, and the duration of sleep is much longer than usual. But these signs can not always alert, sometimes they are regarded as symptoms of the underlying disease. Parents begin to sound the alarm when, in addition to weakness and increased drowsiness, the following symptoms appear in children:

• headache and dizziness;
• a sharp decrease in body temperature (up to 35 C and below);
• cold and wet skin;
• blue lips, heavy breathing;
• loss of appetite;
• jumps in blood pressure;
• profuse sweating;
• reduction in heart rate.

Naphthyzine poisoning is divided into 3 stages: mild, moderate and severe.. With a significant overdose, the pulse and pressure drop to a critical level, coma is possible.

Treatment

If there are even slight signs of poisoning, urgent medical attention is needed. Of particular danger are cases when a child, due to an oversight of adults, drinks naphthyzinum or other vasoconstrictor drugs. Before the arrival of doctors, you need to rinse the stomach with boiled water with enterosgel. Manganese solution in these cases is contraindicated. You can give your child activated charcoal.

The baby must be wrapped in a warm blanket, calmed down and provided with plenty of fluids. You can not give milk, because it helps to accelerate the entry of funds into the blood.

With a mild degree of poisoning, hospitalization is not required. Symptoms of intoxication of the body disappear after discontinuation of the drug. An overdose of moderate and especially severe naphthyzinum requires hospital treatment.

To eliminate the symptoms of the disease and normalize the well-being of children in the first minutes of the arrival of doctors, an antidote naphthyzinum is used. The victim is given atropine sulfate, taking into account the weight and age of the child. Children also need a subcutaneous injection of prednisone. The dosage of drugs is prescribed by the doctor. To exclude the negative consequences of poisoning, all manifestations of intoxication of the body must be stopped in 40-60 minutes. The further course of treatment and recovery in a medical institution is from one to three days.

In some cases, doctors prescribe inhalations with naphthyzinum to children. They are indicated for complicated laryngitis, bronchitis, tracheitis. For their implementation, 0.05% naphthyzine is diluted with saline. The safe duration of inhalation is 3 minutes when carried out no more than 3 times a day. The procedure is quite effective if the prescribed dosages are followed during its implementation. With a runny nose and nasal congestion, inhalations with naphthyzinum will not bring the desired result, so the risk during their implementation is absolutely not justified.

How to prevent poisoning

If parents, for one reason or another, still decide to use Naphthyzine to treat their children, they must observe the following precautions:

• use only a solution intended for children, warn pharmacists about this before buying;
• drip the drug no more than once every 6-8 hours;
• use a pipette to eliminate the error of observing the exact dose;
• alternate the remedy with other vasoconstrictor drugs;
• do not use the drug in infants, limit its use in preschool children;
• in case of a negative reaction of the child's body, immediately call an ambulance.

Instead of instillation, naphthyzinum can be used for lotions. Cotton swabs are soaked in a 0.05% solution and placed in each nostril for 2 minutes. A new swab is used for each sinus.

Doctors recommend using naphthyzinum analogues. Its main active ingredient is part of such drugs as Sanorin (regular and based on eucalyptus oil) and Nafazolin Ferein. Means relieve swelling and inflammation of the mucous membrane of the nasopharyngeal cavity, facilitate breathing and eliminate signs of intoxication in infectious and viral diseases. Eucalyptus oil provides an additional anti-inflammatory effect.

For the treatment of acute respiratory viral infections, chronic rhinitis, and the prevention of influenza, the Aqua Maris Baby spray is used. The drug is made on the basis of natural sea water that has undergone sterilization. The nasal passages are washed with Aqua Maris twice a day. The drug can be used for a long time. Subject to the instructions, manufacturers guarantee the absence of side effects.

Another effective and safe remedy is Aqualar Baby. Its main advantage is the possibility of using it from the first days of a child's life. The release form of the product is a spray in a bottle, equipped with a convenient tip with a limiter. The medicine is also released in the form of drops. The drug has no contraindications and restrictions on admission.

The listed funds belong to more expensive drugs, but their relatively high price is offset by safety and efficacy.

Wanting to alleviate the condition of the baby, parents must weigh all the possible risks and be extremely careful! The ability to purchase a vasoconstrictor without a prescription and at a low price cannot be an excuse for its uncontrolled use without first consulting a doctor and following the instructions for use.

Naphthyzine is a very effective drug that constricts blood vessels in a short period of time. If the drug is used incorrectly, an overdose of naphthyzinum may occur.

Naphthyzine is an effective vasoconstrictor drug

Young parents often ask the question: is it possible to use the drug for babies? Pediatricians are allowed to use naphthyzinum, but if the concentration of drops and dosage are correctly selected. Naphthyzine is produced in the form of drops of 0.05%. A solution of 0.1% is an adult dosage that is strictly forbidden for children to take, as it can cause severe poisoning.

The danger of the drug

Can a child get poisoned by this drug? Of course. Nose drops seem to be harmless, but they are quite capable of harming your baby. Naphthyzine drop poisoning in children is not uncommon. Poisoning with naphthyzinum occurs when inexperienced parents on their own, without the appointment of a pediatrician, treat the child with a runny nose with vasoconstrictor drugs. Young mothers very often turn to medical institutions for help with naphthyzine poisoning.

Reasons why poisoning may occur

Naphthyzinum, like any other drug, can harm the body. Symptoms may appear not only with long-term use, but also with a single use of drops. So, let's see why the most ordinary drops can cause serious poisoning.

• Vasoconstrictor drops called Naphthyzinum are available in plastic bottles. It is not always possible, when pressing on the vial, to drop the required number of drops to the child, the dose in this case may increase several times.
• Parents very often confuse the adult dosage of 0.1% with the children's 0.05%.
• Very often there is a non-compliance with the rules for the use of a medicinal product. The instructions indicate that the drops are forbidden to be used by children under one year old, and young mothers use the drug on their own, which risks causing serious harm to the health of the crumbs.
• Naphthyzine is an effective inexpensive drug that is very popular. For kids, its use can threaten sad consequences.

Naphthyzine drop poisoning in children is not uncommon

First symptoms

Naphthyzine poisoning in children is quite common. In order to determine whether the child is actually poisoned, it is necessary to observe his condition. The first symptoms that you might be concerned about are:

• pronounced weakness and lethargy in the crumbs;
• mood swings, tearfulness;
• spasmodic pain in the head and slight dizziness;
• nausea turning into vomiting;
• decrease in temperature;
• bradycardia;
• hypotension (lowering blood pressure);
• complete refusal of food;
• drowsiness;
• pallor of the skin (skin becomes wet and cold);
• slight constriction of the pupils.

When the first such symptoms are detected, it is urgent to call a qualified medical specialist who will provide the necessary assistance and eliminate the symptoms of an overdose. It is strictly forbidden to carry out treatment at home!

First aid

While you are waiting for the doctor, do not panic so that it is not transmitted to the child. It is necessary to monitor the condition of the baby, calm him down and ensure a comfortable position.

• Monitor the general condition of the child.
• Plentiful drink. It can be ordinary boiled water.
• Monitor your baby's pulse and breathing.
• Wrap in a blanket to keep baby warm.

The medicine must be prescribed by a pediatrician in compliance with dosages

Treatment for poisoning

First of all, treatment should be aimed at eliminating the symptoms of naphthyzinum poisoning. Upon the arrival of the ambulance doctor, it is necessary to tell how the drug was taken and in what dosage. If a mild form of poisoning occurs, the baby will be given first aid on the spot and will write out further recommendations for treatment. In severe cases, they are transported to the hospital and treated in a hospital.

Very often it happens that babies use medical preparations on their own. To prevent this from happening, parents should be careful about the storage of all medicines, that is, keep them out of the reach of children.

Note to new parents

• Do not use the drug for infants.
• Drops should be prescribed by a pediatrician in compliance with dosages according to the age of the child.
• Increasing the dose does not increase the effect of the drug, but increases the risk of developing severe poisoning.
• The recommended dose for a child should not exceed 1-2 drops of a 0.05% solution of Naphthyzinum.
• Proper use of the drug will free the child's airways and make it easier for him to breathe through his nose.
• Due to the fact that the drug is addictive, drops can be used no more than once with an interval of 6-7 hours.
• Efficiently apply the pipette to accurately measure the drop. So you can see the amount of the collected drug.
• In order not to cause addiction in a child, it is necessary to alternate naphthyzine with other drops intended for the treatment of colds in babies.

Naphthyzinum - nasal drops to relieve symptoms of nasal congestion. Many use them for years and fall into a real addiction, losing the ability to breathe on their own. Meanwhile, the drug in large doses and with prolonged use is dangerous not only for health, but even for life. Naphthyzinum poisoning in children poses the greatest danger, but overdoses in adults are also not uncommon.

Composition and purpose of Naphthyzinum

The active substance of the anticongestive agent, alpha-adrenergic agonist, or, more simply, vasoconstrictor drops, Naphthyzine is naphazoline. As auxiliary substances, the composition contains purified water and boric acid.

The drug has vasoconstrictive properties, quickly reduces swelling of the nasal mucosa, exudation (discharge), hyperemia (redness).

The use of Naphthyzinum is indicated for:

• acute catarrhal or allergic rhinitis;
• sinusitis;
• eustachitis (inflammation of the auditory tube);
• to perform the rhinoscopy procedure.

Information about contraindications and side effects

In the annotation to the drug, conditions are prescribed in which Naphthyzin has contraindications for use.

Contraindications

The medicine is contraindicated in:

• arterial hypertension;
• tachycardia;
• diabetes mellitus;
• severe eye diseases;
• chronic rhinitis;
• hyperthyroidism;
• severe atherosclerosis;
• hypersensitivity to the components of the drug.

In addition, there are age restrictions for the use of this medication:

• for a 0.1% solution - up to 18 years;
• for 0.05% solution - up to 1 year.

Side effects

As a result of prolonged use or the use of high doses of Naphthyzinum, side effects may occur:

1. Deterioration of the blood supply to the brain and mucous membranes, as a result of which migraine symptoms, nervousness and weakness are observed, in school-age children the ability to learn is reduced, in younger children vision may deteriorate.
2. Increased blood pressure, headaches.
3. Swelling and inflammation of the nasal mucosa, hyperemia, dryness, burning in the nose.
4. Increased heart rate (tachycardia).
5. Decrease in the duration of action of the drug, provoking the use of higher doses and increase the frequency of their use.

The latter effect is the most common in patients who have used Naphthyzinum for more than 1 week. During this time, the small blood vessels of the nasal cavity adapt to nasal drops, and Naphthyzin ceases to act on them as a vasoconstrictor for a long time. As a result, patients become dependent on the drug, and begin to increase its dosage uncontrollably.

Interaction with alcohol

Due to the fact that the study of the actions of Naphthyzine is still ongoing, and many aspects, including interactions with other drugs and alcohol, are not well understood, it is difficult to talk about the effect of alcohol on the effect of the drug. However, from the experience of practicing physicians, it is known that the intake of alcoholic beverages can cause swelling of the nasal mucosa in patients with dependence on Naphthyzinum, as a result of which they have to "drip" after drinking alcohol.

Is it possible to get poisoned with Naphthyzinum

Given the vasoconstrictive effect of the drug and its ability to be addictive in patients, the question arises whether Naphthyzinum can be poisoned, and how harmful drops are in the treatment of rhinitis in a child.

Consequences of improper treatment

Strictly speaking, Naphthyzinum is not a cure for the common cold as such. These drops serve as an aid to facilitate breathing in various respiratory diseases. Therefore, you can not count on the therapeutic effect of the common cold when using only this drug. And even more so, it is impossible to increase the recommended doses and frequency of Naphthyzinum on your own, because. Is it dangerous.

An uncontrolled increase in doses can lead to dependence on the action of the drug, which will force you to increase its amount even more. And this will already lead to an overdose and poisoning with Naphthyzinum.

Consequences of use in children

Sometimes small children are brought to the intensive care unit, whose parents neglected the warnings in the instructions regarding the age limits for the use of Naphthyzin. The mucous membranes of a small child are much more tender and sensitive than those of an adult. Therefore, even small, according to parents, doses can cause the development of adverse reactions in a child with rather serious consequences. In no case should you use Naphthyzinum, the concentration of which does not correspond to the age of the child or in babies under 1 year old!

What happens if you take the medicine

The worst case scenario can expect a baby who drank the contents of a bottle of Naphthyzinum due to the carelessness of his parents. This happens most often in families with small children, where the mother or other adults are drug dependent on Naphthyzinum. Drops that are used several times a day can be on the couch, under the pillow, on the windowsill, that is, where the baby can easily get them and get drunk.

You can also get poisoned by a low-quality, expired drug, even if you follow all the other rules for use.

Clinical picture in case of overdose and degree of poisoning

Signs of Naphthyzinum poisoning can be manifested by the following symptoms:

• abdominal pain, nausea;
• slow heart rate (bradycardia);
• lowering blood pressure;
• dizziness, drowsiness, lethargy, in children - a sharp deterioration in mood;
• appearance of cold sweat on the skin, blanching.

These symptoms can be both mild and pronounced. The clinical picture depends on the degree of overdose.

• A mild degree of intoxication is manifested by one or more symptoms that quickly disappear when the drug is discontinued and do not require medical intervention.
• The average degree is usually detected by several symptoms at once, but when you stop using Naphthyzin, it goes away on its own and also does not require the patient to be hospitalized.
• A severe degree is the most dangerous, since it primarily disrupts the heart rate - from tachycardia to bradycardia, vomiting and other signs of intoxication may occur, and if measures are not taken, a person may fall into a coma.

Of course, at the first suspicion of a severe degree of Naphthyzinum poisoning, it is necessary to call an ambulance.

How to provide first aid to the victim

The danger of poisoning lies in the fact that the longer the victim is not helped, the more widespread intoxication in the body. The consequences of extensive intoxication can be difficult to predict and sometimes the patient cannot be saved. In order to alleviate the condition of the poisoned person and prevent the further spread of intoxication, it is worth being vigilant before the arrival of doctors.

• Be careful to keep the victim conscious.
• Constantly monitor his respiratory function and heart rhythms.
• Put the victim to bed, cover with a warm blanket and let's drink plenty of warm drinks.
• Watching the pulse, remember or write down its changes, the information may be needed by doctors.

Treatment in a hospital

When the victim is admitted to the hospital, blood will first be taken for biochemical analysis and an electrocardiogram will be made.

1. If the poisoning occurred as a result of an overdose during use, then most often the treatment consists in taking sorbents (for example, Enterosgel).
2. If Naphthyzin was drunk, be sure to wash the stomach, prescribe sorbents and symptomatic therapy.
3. If bradycardia is detected, a subcutaneous injection of an antidote, atropine sulfate, is made.
4. In severe cases, the introduction of Prednisolone may be required, in extremely severe cases, Dopamine, infusion therapy is used.
5. With the moderate severity of Naphthyzinum poisoning, the use of rehydrating solutions is effective. As a rule, in 30-60 minutes, all manifestations of intoxication can be stopped.

The cheapness and availability of the drug provokes people with chronic forms of rhinitis to use the drug uncontrollably and treat their children on their own. But the consequences of an overdose can bring incomparably large expenses for saving the victim from poisoning, not to mention the damage to the health of the poisoned person. Therefore, the use of Naphthyzinum is recommended for 5-7 days, no more.

If after this time the nasal congestion does not go away, you should look for the causes of a prolonged runny nose and other methods of treatment. And for those who are already firmly “addicted” to Naphthyzin, we can advise you to quit it in one motion, in the morning. The first time will be difficult, but no more than 2-3 days. Then the respiratory function will be restored, and you will feel complete freedom from not very useful drops.

Is it possible to harm such a simple over-the-counter drug?

Canadian pediatricians presented an analysis of such a case of an overdose of vasoconstrictor drops: a 4-month-old baby was admitted to the intensive care unit after using vasoconstrictor drops in the nose with congestion for 2 days. The baby received 8 drops of xylometazoline in the nose (conc. 0.1%) 12 hours before the child was admitted to the intensive care unit.
This dosage is for adults, in children it is used only from 6 to 12 years. The child was admitted to the intensive care unit in a coma. The situation ended happily.
The Medline Library has a review of 13 cases of xylometazoline overdose in children under 5 years of age, 11 of which occurred in children under 2 years of age.
Doesn't seem like much, does it? What if it was YOUR child?
In addition, these phenomena can have varying degrees of severity, go unnoticed or simply not documented.
Unfortunately, no minimum non-toxic dose of xylometazoline has been established for these young children. When instilling xylometazoline, pharmacological reference books recommend maintaining an 8-10 hour interval between doses and, in children under 6 years old, use strictly 1 drop of the drug in a children's dosage in each nasal passage. And such a dosage does not pose a danger to children's health.
This is just an example of the misuse of one substance, but this is possible with any vasoconstrictor nasal drops. And, unfortunately, even full compliance with the instructions does not guarantee the absence of an overdose. Since there are data on cases of overdose of oxymetazoline \ xylometazoline in premature babies or babies in the first months of life when taking the drug according to the instructions in children with symptoms of nasal congestion in ARVI.

Overdose symptoms:
respiratory failure or respiratory arrest;

lethargy, up to coma;

blurred vision;
blue lips and nails;
change in pupil size;
violation of blood pressure - first an increase, then a decrease;
tachycardia;
headache;
irritability;
decrease in body temperature;
convulsions;
nausea and vomiting;
trembling of the limbs.

If you suspect a child has poisoning with a vasoconstrictor drug, then you should immediately seek help.
Tell your doctor:
the patient's condition;
height;
weight;
the name of the drug;
terms of use and dosage.

How to avoid such reactions to the drug:
keep medicines out of the reach of children;
do not use vasoconstrictor drops as a self-medication for more than 3 days;
vasoconstrictors do not have a regular intake regimen - this is a means of symptomatic relief, if we are talking about a common cold - there is congestion - we drip. The nose breathes - skip.
With otitis media, the doctor may prescribe a different regimen.
The time interval between doses is of great importance, so for Xylometazoline it is 8-10 hours; Oxymetazoline -12 hours; Phenylephrine - 4-6 hours.
In newborns, without a doctor's prescription, such drugs cannot be used!
It is strictly forbidden to fill in drops for the nose, for example. naphthyzinum, into a nebulizer or other devices and do inhalation!
The release form of vasoconstrictors for children - drops - is much more preferable, so you can definitely see what has got into the nose. Vasoconstrictor drops in the treatment of the common cold are not the most important medicine! Even swelling can be safely removed with hypertonic saline.
Be careful and be healthy!