Can there be constipation. Causes and quick treatment of constipation in adults

Most people are familiar with candidiasis, not just women. Its symptoms are eloquent and unpleasant, and its causes are varied and numerous. Modern pharmacology offers a wide range of drugs used to treat this fungal infection. Pimafucin is often prescribed for thrush, since the drug quickly relieves symptoms and prevents the growth of Candida fungi.

Pimafucin - medicine belonging to the group of fungal antibiotics and having a fungicidal effect. Considered safe for everyone age groups patients, pregnant and lactating women.

The drug is available in several forms that determine its composition:

  • Coated tablets resistant to gastric juice and soluble in the intestine. Packing - a bottle, in everyone on 20 tablets.
  • Intervaginal suppositories. Packing - contour without cell, 3 pieces in each, in a box - 2 packs.
  • Cream for topical use on affected areas of the skin. It is in a tube with a capacity of 30 ml.

In all forms, the active substance is natamycin - it is he who has an antifungal effect.

  • potato starch;
  • polyvinylpyrrolidone;
  • magnesium salt of stearic acid;
  • lactose;
  • sucrose;
  • gelatin;
  • methyl p-hydroxybenzoate;
  • calcium carbonate;
  • cellulose acetate phthalate;
  • white beeswax;
  • glyceryl triacetate;
  • titanium oxide.

Consist of these excipients:

  • cetyl alcohol;
  • solid fat;
  • sorbitol;
  • polysorbite;
  • sodium bicarbonate;
  • carboxylic acid.

In addition to natamycin, it contains:

  • decyloleate;
  • wax;
  • cetearyl alcohol;
  • sodium dodecyl sulfate;
  • preservative E218;
  • propyl parahydroxybenzoate;
  • propanediol;
  • water.

The instructions for use indicate that the product must be stored at temperature regime no higher than 25 degrees, away from children. Shelf life - 4 years, after its expiration Pimafucin can not be used for treatment.

How Pimafucin works

The active substance of the drug penetrates into fungal cells through their membranes and destroys them. The fungi of the genus Candida are most sensitive to natamycin, the pathological reproduction of which leads to thrush.

According to the instructions, Pimafucin has no effect on the vital activity of gram-positive or gram-negative microorganisms.

Natamycin - its action

Natamycin does not have a systemic effect, since it is almost not absorbed from gastrointestinal tract, healthy skin and mucous membranes. Enteric-coated tablets release the active ingredients while they are in the intestines. progressive biochemical research confirm the absence of the active substance in the blood and other body fluids of people undergoing Pimafucin therapy.

Pimafucin suppositories, under the influence of body temperature, turn into foam, which evenly spreads along the walls of the vagina.

The effectiveness of treatment with Pimafucin is expressed in:

  • removal of the main symptoms of thrush literally from the first application: itching and heavy discharge;
  • removal of edema in the vagina;
  • destruction of fungal cells and spores;
  • in pregnant women - improvement general condition women and the fetus, a decrease in tone and the likelihood of premature birth.

When the drug is prescribed

Instructions for use of the drug Pimafucin contains a list of fungal infections various organs organism, which are considered indications for the use of the drug.

Diseases for which it is advisable to use tablets:

  • Mucosal candidiasis oral cavity in acute pseudomembranous and atrophic form, which arose against the background of weakened immunity, including from the use of drugs.
  • Otomycosis or otitis of fungal etiology, complicated by the reproduction of pathogenic fungi.
  • Candidiasis of the skin and nail plates.
  • Inflammatory processes on the glans penis, provoked by the reproduction of Candida fungi.
  • Candidiasis vulvovaginitis, vulvitis, balanoposthitis.
  • as the main and aid dermatomycosis.








Tablets for the treatment of skin can be used alone, with Pimafucin cream or in combination with other drugs, for example, with Griseofulvin.

According to the instructions, with the help of suppositories, diseases of the genital organs are treated:

  • vaginitis, vulvovaginitis, vulvitis caused by candida fungi;
  • sometimes to eliminate pathological discharge and itching in the vagina, not caused by fungi.

The cream is used for the same indications as tablets and for the treatment of ulcers that occur in people with diabetes.

According to clinical studies, Pimafucin proved to be effective in all cases of application. Maximum positive results have been achieved in the treatment of vaginitis caused by fungi of the genus Candida.

Use during pregnancy and lactation

The instructions for use indicate that women during the period of bearing a child and breastfeeding are allowed treatment with Pimafucin for thrush.

Some experts argue that the use of this tool is necessary in extreme cases, because it is not effective and can aggravate the course of thrush. But these conclusions are based on isolated cases, and the drug is the most popular in the fight against the disease. It can be used in all three trimesters, without harm to the health of the mother and fetus.

Dosage of the drug, according to the instructions

The doctor prescribes the drug and its dosage, after comprehensive survey patient. The following schemes for the use of the drug recommended in the instructions are considered standard:

  • The dosage of oral tablets is 4 pieces per day for adults, and 2 for children, for a week.
  • Pimafucin suppositories are administered 1 per day for 3-6 days. If candidiasis is severe, then suppository treatment is supplemented with tablets.
  • Topical application of the cream is prescribed individually, depending on the brightness and severity of symptoms. On average - from 1 to 4 times a day. If necessary, increase the treatment with tablets.

Method of application indicated in the instructions

Intervaginal administration of suppositories must be carried out at night, in the supine position, so that the agent does not leak out, and its effectiveness does not decrease due to its smaller amount.

Dermatomycoses are the most common fat people, and foci of inflammation are usually located in the folds, between the phalanges of the fingers, in inguinal zone and under the mammary glands.

Ulcers in people with diabetes form most often on the feet. When using the cream, it is recommended to continue therapy for another 3-4 days after the symptoms disappear. Otomycosis disease requires the use of a cream up to 4 times a day. The ear canal is pre-cleaned, and after lubrication, it is closed with a cotton turunda.

On critical days, treatment with Pimafucin is interrupted. If possible, therapy should be started after menstruation.

It is recommended to examine the sexual partner for the presence of a fungal infection. Men are its carriers, but candidiasis is not so pronounced in them, often asymptomatically. But if they do not cure thrush, then soon the woman will have a relapse with a probability of 95%.

Sexual contact during the treatment of thrush can not be ruled out, but it is necessary to use barrier contraceptives.

When not to use Pimafucin

According to the instructions for use, Pimafucin is contraindicated in such cases:

  • individual intolerance or hypersensitivity to drug components.
  • Patients with intolerance to lactose, fructose and other saccharides contained in the preparation.

The drug is used to treat children, starting from the newborn age.

The compatibility of the drug with other medicines has not been fully studied.

Side effects

Side effects from the use of Pimafucin are extremely rare, and their list, given in the instructions, is not numerous:

  • At internal reception tablets in the first days of therapy, the patient's condition may be accompanied by nausea and upset stool.
  • Topical application can provoke itching, burning of the skin of the genital organs due to cetyl alcohol in the composition of suppositories.




The drug does not provoke allergic reactions, so far not a single case has been recorded.

Overdose

Cases of overdose with Pimafucin have not been identified or described, which is indicated in the instructions for use of the drug.

Medicine analogs

One of the few drawbacks of the drug is its high price. More affordable analogues are:

  • Irunin tablets - the remedy differs little from Pimafucin in price, is very effective and has practically no contraindications. The active ingredient is itraconazole.
  • Intervaginal suppositories, which have the same active substance (Ecofucin, Primafungin).

Effective, but different in composition, is the new drug Livarol, the main antifungal effect is ketoconazole. Livarol is prohibited for the treatment of thrush in women during the first trimester of pregnancy.

A drugPhotoPrice
from 290 rub.
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from 184 rubles

Analogues include creams - antifungal antibiotics local application:

  • Primafungin - is available in tubes of 20 mg, the active substance is the same as that of Pimafucin.
  • Nystatin ointment - available in tubes of 30 mg, the active substance is nystatin.

In addition to Nystatin ointment, release forms are known in tablets and suppositories. Oral use the drug is contraindicated in children and pregnant women, according to the instructions.

In addition to those listed, affordable analogue is Fluconazole, the price of which starts from 20 rubles. It is available in the form of tablets, capsules and solution for infusion. The active ingredient is fluconazole. Unlike Pimafucin, according to the instructions, it is forbidden to use it to treat children under one year old, and it has much larger list contraindications.

Pimafucin is recognized by many gynecologists as the most effective and safe drug for the treatment of thrush and other fungal diseases. Diversity dosage forms and the simplicity of the instructions makes it easy to use.

Video: Thrush and how to deal with it


Active substance(it's also international) generic name): Natamycin.

Dosage forms:

pimafucin suppositories, tablets, pimafucin cream

Pharmacological action and pharmacokinetics of Pimafucin:

Antifungal polyene antibiotic of the macrolide group with a wide spectrum of action. The drug is active against yeast (Torulopsis, Rhoduturola), yeast-like fungi (Candida albicans), dermatomycetes (Trichophyton, Microsporum, Epidermophyton), other pathogenic fungi (Aspergillus, Penicillium), and Trichomonas.


It has a fungicidal effect. Pimafucin binds sterols of cell membranes, violating their integrity and function, which leads to the death of microorganisms. Dermatophytes are less sensitive to natamycin, but resistance to natamycin in clinical practice does not occur. Not absorbed from the gastrointestinal tract, skin and mucous membranes.

The use of Pimafucin, for which diseases it is used in therapy:

It is prescribed for fungal infections of the skin and mucous membranes, including acute pseudomembranous and atrophic candidiasis after therapy with antibiotics, glucocorticosteroids and cytostatics, genital candidiasis, otomycosis, candidiasis of the skin, nails and intestines, vaginitis, vulvitis, dermatomycosis, etc. They are also used for trichomoniasis. Apply inside and topically.

Clearer gradation by drug form:

pimafucin tablets:

treatment and prevention of non-invasive intestinal candidiasis (including after taking antibiotics, cytostatics, corticosteroids).

pimafucin cream:


skin infections and mucous membranes caused by Candida fungi or other sensitive yeast, yeast-like fungi or dermatophytes (including balanoposthitis, otomycosis).

pimafucin suppositories:

vulvovaginal candidiasis.

Dosing regimen of Pimafucin:

With vaginitis, vulvitis, vulvovaginitis, 100 mg (1 vaginal suppository) is prescribed for 6-9 days. The suppository is inserted into the vagina in the supine position, as deep as possible, 1 time / day at night. With a persistent course of vaginitis caused by Candida albicans, the drug is additionally prescribed orally (1 tab. 4 times / day for 7-10 days) to sanitize the focus of candidal infection in the intestine. For the treatment of candidal lesions of the genital organs of a partner, Pimafucin is used in the form of a cream.

With balanoposthitis, the cream is applied to the affected areas of the skin once or several times a day.

With intestinal candidiasis, adults are prescribed 100 mg (1 tab.) 4 times / day for an average of 1 week. Children are prescribed 100 mg (1 tab.) 2 times / day.

With dermatomycosis (including candidiasis of the skin, diaper rash in children), the cream is applied to the affected skin surface once or several times a day.


With otomycosis, the affected surface is smeared with cream once or several times a day. Before using the drug, the ear is cleaned. After using the drug in ear canal place a tampon made of natural material (cotton, wool).

The duration of the course of treatment is set individually. After the disappearance of the symptoms of the disease, it is recommended to continue treatment for a few more days.

Pimafucin during pregnancy and lactation:

The drug can be used during pregnancy and lactation according to the doctor's indications, in fact, it is one of the drugs of choice during pregnancy.

Side effects from the use of Pimafucin:

Nausea, diarrhea are possible (occurring in the first days of taking the drug in the form of tablets and passing on their own during treatment), slight irritation, burning sensation are possible (when using cream, vaginal suppositories).

Contraindications for use:

Individual intolerance to the drug, porphyria

special instructions:

It should be borne in mind that under the influence of body temperature, vaginal suppositories quickly dissolve, forming a foamy mass, which contributes to uniform distribution active substance.

Pimafucin can be used as additional drug in the treatment of ringworm with griseofulvin.

Cetyl alcohol, which is part of vaginal suppositories, can cause hypersensitivity reactions.


In case of chronic or recurrent infection local treatment can be supplemented by the appointment of tablets and cream.

During menstruation, suppository therapy is interrupted.

However, it is recommended to conduct an examination of sexual partners and, if a candidal lesion is detected, to conduct a course of treatment with Pimafucin. Also, during the treatment period, you should use barrier means contraception.

During the use of suppositories, there is no need to exclude sexual intercourse.

Pimafucin can be prescribed to newborns.

drug interaction:

No interactions with other drugs have been described.

How best to store Pimafucin:

At a temperature of 15° to 25°C. The shelf life of vaginal suppositories is 2 years, tablets and creams are 4 years.

Description of the drug (pimafucin suppositories, cream, pimafucin tablets, etc.) is not intended self-treatment. The drug has contraindications and side effects. Consultation with a specialist is required.

Pimafucin is a modern polyene antibiotic belonging to the group of macrolides. The medicine has a very wide spectrum of action. It has pronounced fungicidal properties, thanks to which it helps well with fungal infections. Most often, Pimafucin vaginal suppositories are prescribed to patients suffering from thrush in its various manifestations.

Table of contents: Active substance and dosage forms Pharmacological action Indications Scheme of application Possible side effects Who should not use Pimafucin? Pimafucin for pregnant and lactating women Interaction with other drugs Additionally Pimafucin analogues Storage rules and conditions for dispensing from pharmacies

Active active ingredient Pimafucin is the antibiotic substance natamycin.

The drug is produced pharmaceutical companies in tablet form, as well as in the form of ointment, cream and vaginal suppositories.


Each Pimafucin suppository contains 100 mg of an antifungal agent.

Candles in yellow or brownish shades are supplied in individual foil packages. In a cardboard box 3 or 6 suppositories.

Natamycin is able to react with the sterols of the cell wall of yeast-like fungi, which leads to its destruction and, as a result, cell death.

This antibiotic is active against a wide range pathogenic fungi. It is exceptionally effective against the causative agent of thrush ( vaginal candidiasis) - Candida albicans. Dermatophytes are also quite sensitive to Pimafucin.

At topical application(in the form of suppositories) the antibiotic is not absorbed into the blood and, therefore, does not have a systemic effect.

Pimafucin vaginal suppositories are prescribed for the following infectious and inflammatory diseases provoked by pathogenic fungal microflora:

  • vaginitis;
  • vulvitis;
  • vulvovaginitis.

The drug allows correct application V as soon as possible get rid of the so-called. "milkmaids".

In infectious and inflammatory diseases of the female organs reproductive system patients are prescribed 1 suppository per day. The tool is intended for course therapy. Average duration course is from 3 to 6 days (terms are determined by the attending gynecologist).

It is advisable to continue antifungal therapy for several days after complete relief clinical signs diseases (itching, burning, pathological whitish discharge).

Pimafucin suppositories are applied topically; they are inserted into the vagina for maximum possible depth, having previously accepted horizontal position. The procedure is carried out once a day, in the evening before going to bed.

With a persistent recurrent course of thrush, the drug must be additionally taken orally in the form of tablets (1 pc. 4 times a day). The duration of the course varies from 10 to 20 days. Oral intake is necessary for the destruction of fungi of the genus Candida in the intestine, i.e., the rehabilitation of a chronic focus of infection.

Note: at the same time, the treatment of the sexual partner is carried out, which, when unprotected contacts inevitably becomes a carrier of a fungal infection. For the treatment of candidiasis in men, Pimafucin cream is used topically (1-3 times a day). The duration of therapy is determined in each clinical case strictly individual (taken into account possible development candidal balanoposthitis).

The vast majority of patients tolerate Pimafucin well.. In some cases (very rarely) there are light feeling burning in the vagina and slight irritation of the mucous membranes due to the presence in the suppositories of such an auxiliary ingredient as cetyl alcohol. These side effects are not grounds for interrupting the course.

Pimafucin suppositories have practically no contraindications for use. The drug is not prescribed only to those patients who have individual hypersensitivity to the active substance.

Vaginal suppositories are perfectly acceptable to use during gestation and breastfeeding baby. Since at local use there is no systemic absorption (absorption), the active ingredient does not enter the blood and breast milk. Data obtained during clinical research, convincingly proved the absence negative impact antibiotic to the fetus.


Drug antagonism and other interactions of Pimafucin with others pharmacological means has not been identified to date.

Under the influence of body temperature, intravaginally administered suppositories quickly heat up, turning into a foamy substance. This contributes to the most even distribution of the antibiotic in the area affected by Candida fungi.

At the time of the monthly course of treatment, it is advisable to interrupt.

During therapy, there is no need to refuse sexual intercourse, but the partner must use a condom or undergo treatment in parallel Pimafucin.

The drug does not affect the reaction rate, so patients can drive a car and work with other potentially dangerous objects.

IN pharmacy chains it is possible to purchase medicines for topical use, which include the same active substance. These are Primafungin, Ecofucin and Natamycin.

With fungal vulvitis and vaginitis, the following suppositories can also be used:

  • Miconazole;
  • Betadine;
  • Polygynax;
  • Zalain;
  • Terzhinan;
  • Livarol;
  • Fluomizin.

A doctor's prescription is not required to purchase this medicine for thrush.

The shelf life of drugs is 2 years from the date of issue (it is indicated on the package).

Keep away from children!

Plisov Vladimir, medical commentator

Instructions for the use of pimafucin in suppositories, a description of the action of the drug, indications for the use of pimafucin suppositories, interaction with other drugs, the use of pimafucin (candles) during pregnancy. Instructions:

Pimafucin in cream

Pimafucin tablets

1 suppository contains: natamycin 100 mg.

1 suppository kuramynda: 100 mg natamycin.

1 suppository contains: cetyl alcohol, solid fat, sorbitone trioleate, polysorbate 80, sodium bicarbonate, adipic acid.

1 suppository kuramynda: cetyl alcohol, katty mai, sorbiton trioleates, polysorbate 80, sodium bicarbonates, adipin kyshkyly.

vaginitis, vulvitis, vulvovaginitis.

vaginitis, vulvitis, vulvovaginitis.

slight irritation, burning sensation.

married titirken, kuydir sezim.

Vaginal suppositories dissolve quickly under the influence of body temperature, forming a foamy mass, which contributes to a uniform distribution of the active substance. In the case of a chronic or recurrent infection, topical treatment may be supplemented by the appointment of tablets and cream.

Ethanol, which is part of vaginal suppositories, can cause hypersensitivity reactions. During menstruation, suppository therapy is interrupted. During the period of treatment with suppositories, there is no need to exclude sexual intercourse. However, it is recommended to conduct an examination of sexual partners and, if a candidal lesion is detected, to conduct a course of treatment with Pimafucin. It is also necessary to provide for the use of barrier methods of contraception during the period of treatment.

Pregnancy and lactation

It is possible to use Pimafucin during pregnancy and lactation.

Features of the effect of the drug on the ability to drive a car or potentially dangerous mechanisms

Does not affect.

Қynaptyқ suppository dene temperature synyn әserіnen tez erіp, kөpirshіktі mass tүzedі, bұl belsendі substancenyң bіrkelkі taraluyna mүmkіndіk beredi. Sozylmaly nemese kaytalanatyn zhұқpa zhұқpa zhұқpa zhұқdayynda zhergіlіktі emge kosymsha retіnde pill men cream tagayyndaluy mүmkin.

Kynaptyk suppository din құramyna kіretin ethanol zhogary sezimtaldyқ reaction son tudyruy mүmkin. Etekkir kezinde suppository emdeudі toktata turada. Suppositories emdelu kezinde zhynystyk katynysty toktatudyn kazheti zhok. Alaida zhynystyk zhұptasyn tekseru, al candidiasis zaқymdanu anyқtalғan zhagdaida Pimafutsinmen emdeu kursyn zhүrgіzu ұsynylady. Sonymen katar emdelu kezіnde contraception bөgegіsh аdіsterіn paidalanudy da қarastyrғan zhөn.

Zhuktilik zhane lactation kezen

Pimafucin lactation zhane zhүktіlіk kezenіnde koldanyluy mүmkin.

Darіlіk preparatyn car nemesse kauiptіlіgі zor mechanismderdі baskaru kabіletіne aser etu erekshelikteri

Aser etpeydi.

Assign 1 suppository for 3-6 days. Suppositories are inserted into the vagina in the supine position, as deep as possible, 1 time / day. for the night. With a persistent course of vulvovaginitis caused by Candida albicans, tablets are additionally prescribed orally (1 tab. 4 times / day for 7-10 days). For the treatment of candidal lesions of the genital organs of a partner, Pimafucin is used in the form of a cream.

3-6 kүn boyi 1 suppository tagayyndaydy. Suppositories tүulіgіne 1 ret tүnge қarai, nauқasty zhatқyzyp, mүmkіndіgіnshe terenіrek қynapқа engіzedi. Candida albicans tuyndatkan vulvovaginitis ұzaқ kaytpasa, tabletkalardy (7-10 kүn boyy tәulіgіne 4 ret 1 tabletdan) іshke қosymsha taғayyndaydy. Zhuptasy zhynys mushelerinin candidiasis zakymdanuyn emdeu ushin cream turindegi Pimafutsindi paidalanady.

No drug interactions have been described.

Darіlermen өzara аrekettesuі sipattalmagan.

Currently, cases of overdose of the drug Pimafucin have not been reported.

Kazirgi kezde Pimafutsin preparations artyk dozalan zhagdaylary turaly khabarlanbagan.

Natamycin is a drug local action practically not absorbed through the mucous membranes.

Natamycin - zhergiliktі аserі bar drug, іs zhүzіnde shyryshty қabyқ arkyly sinbeydi.

Antifungal polyene antibiotic of fungicidal action. Natamycin binds sterols of cell membranes, violating their integrity and function, which leads to the death of microorganisms. Most pathogenic yeast fungi are sensitive to natamycin, especially Candida spp. Dermatophytes are less sensitive. Resistance to natamycin among yeast fungi does not occur in clinical practice.

Fungicides aseri bar zenge karsy polyendi antibiotic. Natamycin zhasusha zhargakhshalary steroldaryn, olardyn tutastygy men қyzmetіn bұzyp, baylanystyrady, bul microorganismderdin қyryluyn аkeledі. Natamycinge captegen pathogenic ashytky zenderi, asirece Candida spp. semimtal. Dermatofitterdin sezimtaldygy azdau. Clinical clinic tazhiribede ashhytky zenderdin arasynda natamyzinge tuzimdilik kezdespeydi.

3 suppositories are placed in a blister pack made of polyvinyl chloride film. 1 blister pack along with instructions for medical use in the state and Russian languages ​​are placed in a cardboard box.

3 suppositories polyvinylchloride ulbirden zhasalgan pishindі ұyashyқty kaptamaғa salyngan. 1 pіshіndі ұyashyқty қaptamadan medicina қoldanyluy zhөnіndegі memlekettіk zhane orys tіlderіndegі nұsқaulyқpen birge cardboard pәshkege salynada.

Information on how to use Pimafucin suppositories can be obtained from your doctor or read in the instructions. Let's talk about this in more detail.

Thrush or candidiasis is one of the contemporary problems that causes discomfort, requires immediate treatment. Nowadays, there are a number of drugs aimed at treating candidiasis, among them Pimafucin suppositories.

Pimafucin, produced in the form of vaginal suppositories, has a yellow-brown color. color scheme, packed in a sealed foil package, duplicating the configuration of a candle. The package contains up to 6 candles.

The active ingredient of the drug is natamycin, a polyene antimycotic belonging to the group of macrolipids, which combines the widest spectrum of action. Thrush microorganisms are most sensitive to the drug; therefore, the drug is used in the treatment of candidiasis.

The drug is indicated for the treatment of candidiasis, as well as a number of its varieties:

  • vulvoginitis;
  • vulvitis;
  • vaginitis.

Thrush, both female and male, manifests itself during a period of decrease immune protection. Mushrooms of the Candida variety during the development of the disease can be found on the mucous membranes of the human genitalia. With normal immunity, they do not lead to the occurrence of candidiasis. However, in case of hypothermia, stress, malfunction metabolic processes organism and hormonal background, during the period of lowering the immune defense and under the influence of other provocateurs, microorganisms are capable of intensive reproduction, which leads to the onset of the disease.

The drug Pimafucin is available in the following forms: tablet, cream, vaginal suppositories.

The tablet form is applicable for the treatment of vaginal candidiasis. As you know, tablets are prescribed to prevent the development of candidiasis in the gastrointestinal tract or to restore the intestinal microflora when using corticosteroid drugs, antibiotics and cytostatics.

The duration of therapy and the dosage of the drug for thrush depend on the doctor's prescription and the results of the tests that the patient takes at the end treatment course, on average, treatment is carried out for 1 week.

Vaginal suppositories - effective remedy to cure thrush in women. They should be inserted into the vagina 1 at a time at night. The course of treatment procedures lasts 10 days in combination with the tablet form of the drug, ingestion (4 tablets per day) is a necessity for the destruction of microorganisms that have penetrated the intestinal flora.

The scheme of using the drug for thrush is standardized: 1 suppository per day, immediately before bedtime. Should not be moistened, the introduction of a vaginal suppository is carried out in a supine position, as deep as possible. After symptoms disappear, continue healing procedures at least 3 days to avoid recurrence. The average duration of the treatment course is 1 week.

In case of complications, the specialist prescribes tablets for the purpose of prophylaxis to prevent intestinal candidiasis or eliminate the existing one. focal lesion GIT. If the external genitalia are affected, Pimafucin cream can be treated.

For men, Pimafucin cream is recommended for use throughout the entire treatment course, to prevent candidiasis and candidiasis in men. There is no need to pause intimate relationships, but no one canceled the protection, barrier protection is recommended.

The following drug benefits are noted:

  1. High sensitivity to active ingredient natamycin, as well as additional components.
  2. Can be taken during pregnancy and lactation.
  3. The drug does not penetrate the mother's bloodstream and does not adversely affect the fetus.
  4. During menstruation, Pimafucin should be taken in tablet form.

The tool has a gentle effect on the body, there are no side effects. In exceptional cases, burning and mild degree irritation.

With the internal administration of the drug, the components do not enter the bloodstream, and do not affect the body systemically. Overdose situations have not been recorded.

Individual intolerance to the components of the drug is the only contraindication to the use of these suppositories.

Candles do not affect the management of transport and other mechanisms.

Implementation is carried out without a prescription. Shelf life - 24 months, store the drug in a dark place at temperatures up to +25°C.

Attention! During critical days therapeutic treatment with thrush is carried out with tablets.

It is recommended that in therapeutic measures both partners were involved, since thrush is also characteristic of the male half, regardless of the fact that it appears in them extremely rarely. At the same time, it is the representatives of the stronger sex who are carriers of candidiasis and can become a source of recurrence of the disease.

Treatment of candidiasis in men is carried out by means of Pimafucin cream. It should be applied to the affected areas of the genital mucosa 1 time per day.

In a complicated form of the disease, the specialist prescribes the application of the drug several times a day. The time period of treatment depends on the prescription of the doctor.


Treatment of thrush. Video

The active substance of Pimafucin is natamycin. Although it belongs to the group of broad-spectrum antibiotics, you should not be afraid of it. Natamycin is practically not absorbed from the gastrointestinal tract, from the surface of the skin and mucous membranes, that is, it does not enter the blood, and hence to the fetus during the development of pregnancy.

However, if in the past you have already noted allergic reactions on Pimafucin, then during pregnancy it can not be used.

Candles can be used even in pediatric practice- for the treatment of the pediatric category of patients, and are not prohibited for use during breastfeeding.

With thrush, you should:

  • limit the consumption of sweets and sweets;
  • consume lactic acid products;
  • refuse synthetic underwear;
  • do not use intimate hygiene products;
  • refuse to use panty liners;
  • engage in strengthening immune defenses.

A large number of women and men who have applied for treatment for candidiasis, who have been prescribed Pimafucin, respond positively to the drug. They note that the effectiveness of treatment with the drug is high, and the duration of therapy is short.

If you have been prescribed Pimafucin suppositories, the instructions for using the drug are required to read.

In it you will find full information about indications for use, side effects, features of use and effect of the drug.

Pharmacological action and indications for use

Pimafucin candles are powerful antifungal agent. The medicine contains macrolide antibiotic natamycin. It has a wide antibacterial spectrum of action and leads to the death of fungal microorganisms by violating the integrity of their membrane. Natamycin is active against microorganisms of the Candida family and dermatophytes. The antibiotic is not absorbed into the alimentary canal and is not absorbed in the skin or mucous membranes.

Pimafucin is prescribed for fungal diseases various etiologies. These can be vulvovaginitis caused by exposure to fungi of the Candida family, fungal diseases organs of the gastrointestinal tract, which arose due to weak immunity or long-term use certain medications. Pimafucin is also prescribed for the treatment of fungal diseases of the skin or nails.

The drug is contraindicated in case of intolerance to natamycin, potato starch, gelatin, lactose or other auxiliary components of the drug. Candles Pimafucin during pregnancy is allowed to use. In addition, the period of breastfeeding is also not a contraindication.

Method of application and reviews

Suppositories must be inserted into the vagina. There is no need to pre-wet the suppositories. The dosage will depend on the severity of the disease and the age of the patient. The duration of the course of treatment varies from 1 week to several months. If the disease is difficult to treat, then drug therapy is supplemented by oral administration Pimafucin tablets. After the disappearance characteristic symptoms disease, it is recommended to use the medicine for a few more days.

Candles from thrush Pimafucin are a gentle remedy, and do not cause a person side effects. However, at the first stages of treatment, there may be a slight burning sensation or itching in the genital area, which will pass on their own over time. If drug therapy is supplemented by taking Pimafucin tablets, then the person has a risk of nausea or diarrhea.

Reviews about Pimafucin

Angela, 32 years old. When I was pregnant for the second time, I was diagnosed with thrush. The doctor advised me to use Pimafucin suppositories. A week later, the symptoms of candidiasis were gone. The drug has a gentle effect, so I did not have any side effects. I am satisfied with the candles.

Victoria, 26 years old. WITH young years suffered from chronic thrush. No pills and suppositories helped me. Recently I came across an article on the Internet about Pimafucin suppositories, the reviews about the drug were extremely positive. Decided to take this medicine. After the course of treatment, which lasted about 2 weeks, the symptoms of candidiasis disappeared.

Tamara, 23 years old. After giving birth, I had curdled discharge from the vagina. The doctor said that this is thrush, and it often occurs in women after childbirth due to weakened immunity. The doctor prescribed Pimafucin suppositories for me, because they are safe and not capable of harming the baby. The medicine helped - after a few days my condition improved significantly. I recommend everyone to use sanitary pads during the use of suppositories, as the medicine can leave yellow stains on underwear.

Pimafutsin's analogs

The best analogues of Pimafucin candles are Primafungin and Livarol.

Primafungin has similar composition and operating principle. The medicine can be used during pregnancy and breastfeeding. There are no side effects of the drug. It is impossible to use Primafungin only with intolerance to natamycin. It should be noted that suppositories are forbidden to use during menstruation.

The active ingredient in Livarol is ketoconazole. This substance has a wide antifungal spectrum actions. Ketoconazole is active against yeast-like fungi and dermatophytes. You can use Livarol suppositories in the treatment of vaginal candidiasis and as a prevention of fungal diseases. Do not use the medicine in the presence of allergic reactions to ketoconazole or auxiliary components Livarola. Among the contraindications, the first trimester of pregnancy can also be distinguished. Usually Livarol does not cause side effects, but some people experience irritation and a burning sensation in the genital area during the use of the medicine. Moreover, in the early stages drug therapy dizziness and nausea may occur.

"Pimafucin" is a modern drug containing a polyene antibiotic, which belongs to the group of macrolides. The drug has a very broad spectrum of action, which is achieved due to strong fungicidal properties, which helps in active struggle with fungal infections. The drug "Pimafucin" is prescribed to women who suffer from vaginal candidiasis, or, as this disease is also commonly called, thrush.

They are also effective in diseases such as trichomoniasis, as an additional tool in the implementation complex therapy diseases.

Analogues of candles "Pimafutsin" will be considered in this article.

Vaginal candidiasis

This disease is one of the most common in the field of gynecology today. The so-called thrush is fungal infection mucous membrane of the vaginal wall, which is provoked by fungi of the genus Candida. The disease can occur under the influence of a wide variety of factors, which include a decrease in general immunity, unprotected sex, taking medications. antimicrobial agents and antibiotics. On different stages almost every woman faces this problem. For many, this may be due to the onset of menstruation or frequent stress.

Almost every person is a carrier of the fungus, but the indicators of its quantity in the body must comply with certain standards. However, in cases where the fungus begins to actively reproduce, a woman experiences symptoms such as a sharp burning sensation in the vulva and severe itching. Main Feature thrush, which distinguishes it from other inflammatory and infectious diseases of the genital organs, are specific secretions similar to curd mass. Similar symptoms disappear, as a rule, already in the first days of treatment, however, to achieve a stable and lasting effect it must be carried out in a course of at least 10 days, together with a sexual partner.

Consider how Pimafucin candles work. Analogues will be presented below.

Pharmacological properties of the drug

Main active substance medication- natamycin (an antibiotic belonging to the group of macrolides). This substance is able to actively respond to cell membranes yeast-like fungi, which contributes to their destruction and death. In addition, natamycin is active against some other pathogenic microorganisms, which may cause vaginal dysbacteriosis and milkmaid. Pathological bacteria such as dermatophytes are also sensitive to this active substance.

When applied topically in the form of suppositories, the drug "Pimafucin" is not absorbed into the blood, which does not cause any systemic disturbances in the functioning of the whole organism.

Part vaginal suppositories, in addition to the main active ingredient, there are also auxiliary ones - lactose, potato starch, gelatin and others.

Release form

One suppository contains 100 mg active substance. Candles have a yellowish, and sometimes brownish tint and are available in packs of 3 or 6 suppositories. It is easy to find analogues for Pimafucin candles cheaper.

Indications for use

Vaginal suppositories are prescribed for the following diseases:

  • vulvitis;
  • vaginitis;
  • vulvovaginitis;
  • vaginal candidiasis.

drug interaction

Incompatibility with the components of other drugs in the candles "Pimafucin" and analogues have not been identified.

Method of application and dosage

For any infectious and inflammatory diseases of the genital organs, the drug is prescribed once a day. The drug is intended for treatment by a course, and its duration should be at least three days with easy course disease, and less than six days - with an average.

The agent should be used topically, by insertion into the vagina on maximum depth while maintaining a horizontal position of the body. This should be done once, before going to bed. This confirms the instructions for use for Pimafucin. Candle analogues, as a rule, are used in the same way.

With systematic recurrent manifestations of vaginal candidiasis and other diseases that are provoked by the reproduction of pathogenic microorganisms, it would be advisable to take antifungal drug inside in the form of tablets against the background of the main treatment with vaginal suppositories. The duration of such a course should be at least 10 days. Tablets are needed in order to destroy the foci of infection in the intestines, which can be chronic.

Should be paid Special attention to the fact that treatment should be carried out in relation not only to the patient, but also to her sexual partner, since he can also be a carrier of the infection. For the treatment of a partner, you can use the drug "Pimafucin" in the form of a cream, which should be applied to the genitals several times a day. The duration of the course of such treatment varies from the degree of the disease and is determined in each case individually.

Is it possible to use Pimafucin suppositories and analogues during pregnancy? Consider below.

Side effects

Side effects of this medication may include mild itching and burning in the genital area, as well as slight irritation of the mucous membranes of the vagina. This action may be due to the fact that the drug contains cetyl alcohol as an excipient. Despite manifestation of symptoms associated with side effects, treatment interruption is not recommended. Another side effect from the use of vaginal suppositories is that in the first days of treatment, the symptoms of thrush may worsen slightly, but this should also not be a reason to stop therapy. This points to the Pimafucin candles instruction. Analogues should be selected by a doctor.

Contraindications

The only contraindication for women who are prescribed the drug is individual intolerance active or excipients of the drug. In extremely rare cases local allergic reactions may occur in the form of itching and discomfort into the vagina.

Use during pregnancy and lactation

Vaginal suppositories approved for use by lactating women, as well as those who are in the process of bearing a child. When applied topically, the components of the drug are not absorbed, so they do not enter the blood of the expectant mother and milk.

Vacation conditions and storage rules for vaginal suppositories "Pimafucin"

In order to purchase this medical device in a pharmacy, a doctor's prescription is not required. The medicinal product must be stored at moderate low temperatures.

Analogues of candles "Pimafutsin"

In pharmacies you can find medications containing the same active ingredient. They are Primafungin, Natamycin and Ecofucin.

In addition, there are a number of drugs that are not analogues of Pimafucin suppositories for thrush, but have a similar pharmachologic effect. These include:

  • "Betadine".
  • "Terzhinan".
  • Fluomizin.
  • "Livarol".
  • "Polygynax".
  • Miconazole.
  • "Zalain".

What price is better to buy analogues for Pimafucin candles? These will be cheaper means: "Metronidazole", Fluconazole, Ecostat, Hexicon, Flucostat.

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