Valocordin is calming. Indications for use

Valocordin: composition, properties, indications and contraindications, application features

The accelerated pace of life of a modern person, improper daily routine, constant nervous overload, psycho-emotional stress and irregular nutrition quite often lead to unpleasant symptoms from the central and autonomic nervous system.

Ignoring functional disorders due to lack of time to visit a doctor, it can provoke serious consequences - hypertension, heart attacks, strokes, stomach ulcers and other diseases. That is why a person experiencing chronic psycho- emotional stress, in no case should ignore the appearance of unpleasant mental symptoms, and in many cases it will be advisable to take drugs with a mild calming (sedative) effect.

Of course, any drug should be prescribed by a doctor, especially if we're talking about O potent substance as part of a drug that can be sold in a pharmacy only with a doctor's prescription. But there are sedatives that are quite harmless and available for sale in pharmacy chain over the counter. One of these drugs is Valocordin.

Composition and mechanism of action of the drug

Valocordin is always available in the form of drops, the basis of which is water with 96% ethyl alcohol dissolved in it (411.97 mg and 469.75 mg, respectively). Phenobarbital is dissolved in water and ethyl ether bromoisovaleric acid, each substance 18.4 mg. In addition, the drug contains peppermint oil (1.29 mg) and hop oil (0.18 mg).

The mechanism of action of Valocordin, according to the instructions, is due to the properties of these substances, which complement each other’s effect.

So, phenobarbital has an anticonvulsant, sedative and mild hypnotic effect due to a slight inhibition of impulse transmission in the synapses of brain neurons.

Bromoisovaleric acid ethyl ester similar in action to valerian rhizome, also providing a hypnotic and sedative effect.

Oil peppermint, the main active ingredient of which is menthol, promotes irritation of receptors oral cavity and upper respiratory tract, which reflexively promotes the dilation of blood vessels in the heart, bronchi and brain. Thus, sedative and antispasmodic effects are also manifested.

Such effects are indispensable in the treatment of pathologies of the nervous system, because this increases the blood supply to the brain, which reduces the risk of developing hypoxia - oxygen starvation. In addition, the patient’s processes of impulse conduction in the brain are inhibited, which is expressed in severe sedation within a few minutes after taking the drug.

Indications for taking Valocordin

Typically, Valocordin helps well with functional disorders of the nervous system, while more serious illnesses require the prescription of other drugs (antidepressants, tranquilizers, etc.). That is why it is better to consult a doctor before taking a course of the drug. However, anyone can take Valocordin situationally, for example, under severe psycho-emotional stress.

A course of taking Valocordin is indicated for such disorders of the central nervous system as:

• Psycho-emotional lability, excessive and constant stress,
• Neuroses, in particular obsessive-compulsive neurosis,
• Sleep disorders (superficial short sleep, after which a person wakes up tired and exhausted, nightmares, problems falling asleep, etc.),
• Hypochondria, in which the patient seeks severe and dangerous diseases, instead of recognizing the psycho-somatic factor.

In addition to functional disorders of the central nervous system, taking valocordin is indicated for vegetative-vascular dystonia, the manifestations of which are:

1. (pain in the heart area of ​​​​non-ischemic nature),
2. Headache, including migraine and/or tension headache type,
3. Initial stages, especially in young patients due to constant stress, due to the relaxation of vascular smooth muscle muscles and a decrease in blood pressure,
4. – sweating, coldness of the skin of the extremities, chills and tremors of the extremities when exposed to a powerful stress factor, etc.),
5. Abdominal pain due to intense mental stress due to spasm of intestinal smooth muscles.

Quite often, Valocordin is used to relieve an attack of angina, especially if the patient cannot tolerate nitroglycerin. Some doctors are skeptical about taking valocordin in this case, because the “gold standard” for stopping an attack is nitroglycerin. However, Valocordin is really capable of temporarily relieving an attack of pain in the heart, since it has a dilating effect on the blood vessels of the heart, which ensures blood flow to the heart muscle. Of course Valocordin does not prevent the development of myocardial infarction, and sometimes even contributes to a serious outcome, because sedative effect often induces the patient to ignore dangerous symptoms.

Contraindications

As a result of the fact that phenobarbital is metabolized in liver cells, and the products of its metabolism (metabolites) are excreted from the body by the kidneys, the drug is contraindicated in severe stages of liver and kidney failure. In addition, phenobarbital affects the metabolism of other drugs in the liver, enhancing or weakening it. This can lead to the accumulation of metabolites of those drugs that the patient takes together with valocordin, and, as a result, to poisoning of the body.

Besides, absolute contraindication for the use of valocordin is pregnancy and breastfeeding, since through the placenta and breast milk penetrates not only ethyl alcohol, but also phenobarbital, which can have Negative influence on the developing brain of the fetus and newborn child. For pregnant and lactating women, it is only suitable to take valerian in tablets (only as prescribed by a doctor!), but not valocordin.

Mode of application

The drug is used only internally, 15-30 drops three times a day before meals, after dissolving in a small amount of water, unless a different dosage regimen is prescribed by your doctor. As a rule, the sedative effect occurs immediately, intensifying after a few days from the start of use and reaching a maximum by the end of the first month of regular use. It is not recommended to take the drug for more than a month.

Are there any possible side effects?

Despite the fact that Valocordin contains fairly harmless substances, and phenobarbital is in low concentrations, taking the drug can lead to undesirable consequences. Thus, the most common side effect is the occurrence of severe drowsiness and severe inhibition of psycho-motor reactions. Especially these phenomena often develop in case of overdose.

When taking the drug for the first time, in extremely rare cases, you may experience allergic reactions, from minor, by type allergic dermatitis, to quite serious, like widespread urticaria and Quincke's edema. Of course, such reactions are very rare, but it is impossible to predict their occurrence due to strict individual reaction each organism to one or another drug.

At long-term use drug (more than a month), chronic poisoning with bromine (as part of bromoisovaleric acid) is possible, manifested by depression, apathy, chronic runny nose and conjunctivitis).

Impact on ability to drive

Due to the fact that Valocordin most often must be taken by the patient more than once, but according to the course of treatment prescribed by the doctor, in the first days it is better for the patient to stop driving. If after a few days the patient has successfully adapted to increased inhibition in the cerebral cortex, and he does not experience severe drowsiness and inhibition of reaction, he can get behind the wheel.

However, it should always be remembered that any reaction to a drug is strictly individual, and if some individuals remain able to normal speed reaction required when driving a car, then in another part of patients, lethargy may be dangerous to life and health as a result of insufficient concentration of attention while driving.

Can I take the drug with alcohol?

Of course, in the life of every person a situation may arise when he is presented with the opportunity to drink alcoholic beverages - a birthday, a holiday with colleagues, etc. Phenobarbital, which is the main active ingredient, together with ethyl alcohol, which is found in alcoholic beverages in an incomparably greater amount concentration, can give a rather unpredictable reaction. This is due to the fact that each person initially has a purely individual reaction to alcohol due, again, to the individual production of the enzyme alcohol dehydrogenase. If the work of this enzyme is insufficient, then drinking alcohol in combination with valocordin can lead to adverse consequences– severe intoxication, nausea, vomiting, up to alcohol poisoning. That is why drinking alcoholic beverages during a course of treatment with Valocordin is extremely undesirable.

Analogues of the drug

Analogues of valocordin are drugs such as valoserdin and. The composition, mechanism of action and method of administration are identical, and the difference between them only lies in the country of origin. Thus, Valocordin is produced by European pharmaceutical factories, and these two analogues exist only on the Russian pharmaceutical market. The differences between these drugs are in price - the cost of Valocordin ranges from 150 rubles for 20 ml drops to 340 rubles for 50 ml drops. The cost of analogues is several times less - 16-20 rubles - the price of Corvalol and 50-70 rubles - the price of Valoserdin. In addition, the difference is more convenient form release of Corvalol in tablets, because it is not always possible to dissolve the drops in water, and many people cannot tolerate Strong smell menthol drops.

Thus, it should be noted that Valocordin is quite effective drug, helping to reduce psycho-emotional stress and manifestations autonomic dysfunction. However, it should be understood that sedatives for a patient are like crutches for a limping person - they should be used only for the period of recovery. That is, you cannot constantly take sedatives, and during a course of taking them you should make lifestyle adjustments and rethink your attitude towards constant nervous overload, learn to rest and relax properly, in other words, develop a certain resistance to stress, because this is precisely the key strong psyche and a healthy body.

Video: about Valocordin in the program “Live Healthy!”

Video: report on the prospects of Valocordin

For sleep disorders, insomnia, and difficulty falling asleep, doctors recommend that patients take Valocordin. This one is comprehensive active drug has a relaxing effect on the central nervous system and helps you fall asleep faster and get rid of sleep problems. Familiarization with the instructions for use of the medication will allow you to use the product correctly.

What is Valocordin

According to the accepted medical classification, Valocordin drops are classified as sedatives. Additionally, it can be used as an antispasmodic because it relaxes smooth muscles internal organs. The medication is different complex composition– phenobarbital and ethyl bromizovalerianate are declared as active ingredients.

Composition and release form

From the instructions for use attached to each bottle you can find out the detailed composition of Valocordin drops:

Action of Valocordin

In small doses, the active substances in the composition have a sedative and hypnotic effect, at high levels they have a narcotic effect. Phenobarbital is a derivative of barbituric acid, inhibits the inhibitory system of the reticular formation, and is capable of slightly lowering blood pressure. The substance is absorbed in the stomach, 35% of the dose is bound to blood plasma proteins, the rest is filtered in the kidneys.

Reabsorption of phenobarbital occurs at low levels of acidity, and reverse diffusion is impossible due to the alkalinity of the urine. 30% of the substance is excreted in the urine, some is oxidized in the liver. Long-term use the drug leads to the accumulation of the substance in the plasma, liver enzymes are induced. This leads to an acceleration of the oxidation process of phenobarbital.

Ethylbromoisovalerate has a sedative and antispasmodic properties, acts like a phenobarbital synergist, that is, it provides rapid attack efficiency. The substance releases boron in the body, which is slowly released from the body. Long-term use of the drug threatens chronic intoxication boron Peppermint and hop oils have reflex, vasodilating and antispasmodic effects.

Indications for use

The main goal the use of the medication is to eliminate sleep disturbances. In addition, indications for use of the drug are:

• insomnia, cardiovascular cardialgia;
• sinus tachycardia, neurotic conditions;
• pain in the heart, ischemia of the heart muscle;
• vegetative lability, increased irritability;
• hypochondriacal syndrome;
• early stages arterial hypertension;
• spasm of organ muscles gastrointestinal tract(intestinal, biliary colic);
• anxiety caused by psychosomatic phenomena;
• brain disorders, neuroses accompanied by a feeling of fear.

How to take Valocordin

The drug is taken orally before meals, 15-30 drops. They are first dissolved in 30-50 ml of water and repeated 2-3 times a day. With tachycardia single dose can increase to 40-50 drops. Children are advised to take 3-15 drops/day. The dosage for a child depends on age and clinical picture diseases. The course of taking the solution is determined by the doctor.

How long does Valocordin take to work?

Doctors note that the medication begins to act very quickly. This is due to the instant absorption of the active components from the stomach. When taken on an empty stomach, the properties of Valocordin begin to unfold within a few minutes. Similarly, adverse reactions are quickly observed in case of individual intolerance, so during treatment it is worth carefully monitoring the patient.

On early stages hypertension Valocordin can be used to reduce blood pressure. It dilates blood vessels, relieves spasms, increases the clearance between vascular walls. If you have low blood pressure, it is prohibited to use the medication, as it can aggravate the patient’s condition and lead to critical symptoms if the recommended dosage is exceeded.

special instructions

When taking Valocordin, you need to pay attention to some instructions in the instructions. Excerpts from the special instructions paragraph:

• the drug reduces concentration and speed of psychomotor reactions, so during the treatment period you should be careful when driving a car and operating machinery;
• If pain in the heart area does not go away after taking the medicine, consult a doctor to eliminate the risk of acute coronary syndrome;
• the drug is used with caution for hyperkinesis, hyperthyroidism, adrenal hypofunction, heart failure, severe arterial hypotension, constant pain, acute intoxications medications;
• long-term therapy Valocordin is not recommended due to the risk of developing drug dependence, bromine accumulation and the development of poisoning with this substance.

Valocordin during pregnancy

The drug is prescribed with caution by doctors during pregnancy and lactation, because phenobarbital and bromine may have bad influence for the fetus and newborn. If potential benefit for the mother will exceed possible risk for the baby, the doctor will allow the use of the medication, but will carefully monitor all vital signs.

Drug interactions

Some combinations of Valocordin drops with drugs are undesirable due to the risk of toxicity. Risky combinations:

• drugs that depress the central nervous system mutually enhance the sedative-hypnotic effect of the drug, which threatens respiratory arrest;
• phenobarbital accelerates the metabolism of coumarin derivatives, antibiotics, sulfonamides, enhances the effect of analgesics, neuroleptics, anesthetics, tranquilizers, increases the toxicity of methotrexate;
• at sharing the effectiveness of Metronidazole is weakened, indirect anticoagulants, tricyclic antidepressants;
• monoamine oxidase inhibitors prolong the effect of phenobarbital, Rifampicin weakens its effect;
• non-steroidal anti-inflammatory drugs lead to stomach ulcers and bleeding;
• combinations of Valocordin with thyroid hormones, Doxycycline, antifungal drugs from the azole group, Chloramphenicol, Griseofulvin, oral contraceptives, stimulants and glucocorticosteroids - due to weakening of the effect.

Alcohol compatibility

It is forbidden to combine Valocordin with alcohol, because they are both broken down in the liver. The drug also contains ethanol, so the liver has a double load. Ethyl alcohol increases the effect of phenobarbital and increases the toxicity of other components. Possible problems a combination of two components becomes painful colic, inhibition of the central nervous system, excitability or severe lethargy. The person suddenly falls asleep, and severe tremors of the limbs appear.

Side effects

The use of Valocordin entails side effects. Common ones are:

• drowsiness, dizziness, allergic reactions;
• decreased concentration, depression, apathy;
• rhinitis, conjunctivitis, hemorrhagic diathesis;
• chronic bromine poisoning, drug addiction, asthenia;
• weakness, lack of coordination of movements;
• nystagmus, ataxia, hallucinations;
• agitation, insomnia, fatigue, slow reactions;
• headaches, osteogenesis, rickets, osteopenia, osteoporosis;
• nausea, vomiting, constipation, heaviness in the epigastrium;
• agranulocytosis, anemia, thrombocytopenia, bradycardia;
• low blood pressure, urticaria, angioedema;
• skin rashes, itching, acne, lacrimation, anxiety.

Overdose

Symptoms acute overdose barbiturates cause dizziness, fatigue, deep dream(difficult to wake up the patient), swelling of the face, rash, itching. Severe poisoning manifested by tissue hypoxia, coma, rapid heartbeat, arrhythmia. May happen vascular collapse, reflexes are lost. If left untreated, pulmonary edema or respiratory paralysis develops, leading to death. Long-term use of Valocordin leads to bromine poisoning, manifested by confusion, ataxia, apathy, depression, colds and acne.

Treatment of overdose consists of stabilizing and normalizing breathing and blood circulation in a hospital setting. The patient is given artificial respiration, shock is eliminated by introducing plasma substitutes. Used for gastric lavage Activated carbon and sodium sulfate. You can perform forced diuresis, hemodialysis, hemoperfusion. A solution of table salt with saluretic agents accelerates the removal of bromine. For hypersensitivity reactions, indicated antihistamines.

Contraindications

Valocordin is prescribed with caution during pregnancy and lactation. Contraindications for its use are:

• increased sensitivity to components;
• severe liver or kidney failure;
• porphyria, diabetes;
• depressive state, myasthenia gravis;
• alcoholism, medication, drug addiction;
• respiratory diseases with shortness of breath, obstructive syndrome;
• pronounced arterial hypotension;
• acute heart attack myocardium.

Terms of sale and storage

The drug is available without a prescription and can be stored for five years at temperatures up to 25 degrees away from children.

Analogs

Complete analogues Valocordin does not exist in composition; only approximate synonyms with the same are identified active substances. Substitutes include products with similar effects. Analogues of the drug:

• Barboval – contains menthol in the air, available in drops and capsules;
• Valecard - drops and tablets with a similar composition;
• Corvalcaps - capsules with increased percentage active ingredients;
• Darvilol, Carditab, Corvalol, Corvaldin, Corvaltab, Morozov drops – inexpensive analogues facilities.

Valocordin price

You can buy Valocordin in pharmacies and online stores. The cost of the drug depends on the volume and level of trade margin. The approximate prices for the medicine produced by the German company Crevel Meuselbach and its analogues in Moscow will be:

Valocordin is a combination drug primarily used in cardiology. It is most often used to relieve heart pain, tachycardia, nervousness or insomnia. At the same time, the medicine has a minimum of side effects and is relatively cheap, which contributed to its popularization. How to use Valocordin correctly? What dosage should you follow? Is an overdose possible and what are its symptoms?

Valocardin is a solution based on the following components:

• alpha-bromoisovaleric acid ethyl ester (2%);
• phenobarbital (2%);
• peppermint oil (0.15%);
• hop oil (0.01%).

As medicinal base regular ethyl alcohol is used in combination with distilled water. Alcohol acts as a preservative, preventing the oxidation of the main components.

Ethyl ester of alpha-bromoisovaleric acid acts as a sedative, also gives a slight hypnotic effect, and at the same time is an antispasmodic.

Phenobarbital complements the action of ether, and at the same time expands the lumen of blood vessels. Due to the latter, it decreases slightly arterial pressure. This effect is complemented by mint oil, which also has a vasodilating effect on blood vessels and the cardiovascular system as a whole.

According to the instructions, indications for use of Valocordin are:

• nervousness;
• high blood pressure (without severe hypertension in the chronic stage);
• tachycardia;
• spasms (constriction) coronary vessels;
• insomnia;
• general irritability;
• sinus tachycardia.

Regarding hypertension, Valocordin can only be used for initial stages diseases. In advanced cases, we do not recommend taking the solution, since therapeutic effect will be insufficient.

Release forms

On this moment Valocordin is available exclusively in the form ready solution for oral administration. Bottles - 20 and 50 milliliters in cardboard packaging with a special dispenser for convenient counting of drops. Previously, Valocordin was also produced in the form of micro-vias for a single dose, but later manufacturers abandoned it (for financial reasons).

• 15-20 drops before a planned meal, with a small amount of water, 2-3 times a day - for nervousness, high blood pressure;
• 30-40 drops before meals, washed down with water or unsweetened cool tea - for tachycardia, heart pain - up to 2 times a day;
• 3-10 drops 2 times a day - up to 18 years (the exact dosage should be checked with your doctor or pediatrician).

The course of treatment for each patient is compiled individually.

It is worth considering that with long-term use of Valocordin, an addiction effect occurs (mild dependence), and with a sudden cessation of use, a “withdrawal” syndrome occurs. This is due to an increase in bromine concentration in the blood and subsequent “bromism” during long-term therapy.

Drops are allowed to be dissolved in water or cooled unsweetened tea before taking. The only caveat is no more than 30 milliliters of liquid per 10 drops. If there is more water, the effectiveness of Valocordin will decrease due to the slow absorption of the active ingredients into the blood.

Price

Average cost of Valocordin in pharmacies Russian Federation is 150 rubles. Prices differ slightly among different suppliers (no more than 10 rubles).

Analogs

The following drugs are analogues, completely identical in composition:

• Barboval. The composition is completely similar. The only differences are in the form of release. This medicine is available in 25 ml bottles and capsules for oral administration. Average price – 55-60 rubles (drops);
• Valecard. Also has an identical composition, but without peppermint oil and hop extract. It is considered a little less effective. Average price – 40-45 rubles (drops, 20 milliliters in a bottle);
• Corvalcaps. The same Valocordin, but in the form of capsules for oral administration. One pill corresponds to 15 drops. The average price is 100 rubles per package (10 tablets).

But analogues with a different composition, but similar action, the following medications can be called:

• Reladorm. Mainly used to treat insomnia and nervousness. Available in tablets, the active ingredients are Diazepam and Calcium Cyclobarbital. Average price – 450 rubles (pack, 10 tablets);
• Somnol. Active substance- Zopiclone. Mainly prescribed for sleep disorders and emotional stress (one-time dose, no course). Price – from 89 to 120 rubles.

If a doctor has prescribed Valocordin, you should not replace it with analogues at your own discretion. You should further consult your doctor about this.

Contraindications

Contraindicated according to official instructions, are:

• liver or kidney failure;
• hypersensitivity to the active ingredients.

Prescribe with caution medicinal product during pregnancy and during breastfeeding (lactation). Some active ingredients penetrate into the blood and from there are transported to the fetus or into mother's milk.

A categorical contraindication is simultaneous administration other sedative drugs. Their combination can negatively affect work of cardio-vascular system, or even provoke heart attack, severe hypotension.

Valocordin is also prescribed with caution to people retirement age(after 60-65 years) due to possible negative effects on the cardiovascular system. For them, it is recommended to reduce the dosage to the minimum possible meaning(10 drops 2 times a day). In this regard, you need to consult with your attending cardiologist.

Possible side effects

Taking Valocordin may be accompanied by the following side effects:

• dizziness and headaches;
• drowsiness;
• slow reaction and decreased ability to concentrate;
• stomach upset;
• allergic reaction (hypersensitivity to the main components).

Long-term use of the drug may be accompanied by slight dependence. To eliminate its symptoms, no manipulations should be undertaken. It is enough to refrain from taking Valocordin for 5-10 days.

Due to the fact that taking the drug is accompanied by a decrease in the speed of attention, it should be taken with extreme caution by people whose work directly depends on their reaction (drivers, conveyor line operators, and so on).

Drug interactions

Taking Valocordin together with other sedatives leads to an increased effect of both drugs. The same applies to tranquilizers, antipsychotics, alcohol (and drugs based on it).

Joint reception with central nervous system stimulants reduces the effectiveness of the latter, and at the same time can contribute to a sharp increase in the frequency of contraction of the heart muscle.

Due to the fact that some components of Valocordin are absorbed in the liver (phenobarbital), it is not recommended to combine its use with other drugs that also affect liver function - this can provoke acute liver failure. And phenobarbital, as clinical trials show, inhibits the effect oral contraceptives(non-hormonal type). Accordingly, you should temporarily stop taking them and replace them with condoms.

Overdose symptoms

The manufacturer of the drug does not provide precise data on overdose. However, it is known that a single dose of more than 20 milliliters of Valocordin (corresponding to 1 bottle) can cause symptoms of combined intoxication. This is complemented by severe drowsiness and impaired coordination of movements. Visually, this is similar to ordinary alcohol intoxication.

Excessive dosage can provoke vascular collapse, as well as disruption of the central nervous system. The worst scenario is a violation respiratory function(from the side of the brain). If the victim is not provided with timely assistance, then high probability lethal outcome.

What to do in case of overdose? First of all, rinse the stomach with plenty of water or potassium permanganate solution, and then apply symptomatic treatment. Taking sorbents will not help positive effect. In critical cases, the patient is resuscitated (artificial respiration, indirect massage heart, forced ventilation).

Corvalol increases or decreases blood pressure. Composition of the drug, action and indications. Rules for taking Corvalol for high blood pressure.

Valocordin lowers blood pressure
How does Corvalol affect blood pressure?
Corvalol is a well-known sedative, which until recently was necessarily found in every home medicine cabinet. It is still used for various ailments associated with disruption of the cardiovascular system.

Corvalol dilates blood vessels, relieves tension, and calms. Its analogue is no less famous drug valocordin.
The composition of Corvalol includes the following substances:
ethyl ether;
phenobarbital;
alpha-bromoisovaleric acid;
peppermint oil.
relieves spasms;
significantly dilates blood vessels;
stabilizes the functioning of the nervous system.
Main indications of Corvalol:
neuroses of any origin;
tachycardia;
insomnia;
vegetative-vascular dystonia with high blood pressure;
irritability, excitability, tearfulness.
Corvalol and blood pressure
Does Corvalol increase or decrease blood pressure?

This question interests many who resort to his help in various reasons. This remedy is a vasodilator, which means it lowers blood pressure. In this regard, the drug is often used by hypertensive patients to lower blood pressure.
People with low blood pressure are not recommended to take Corvalol, since it does not raise it, but lowers it.

Hypotonics can replace it with sedatives with similar effect, but which do not affect blood pressure in any way. If a person with low blood pressure needs to take Corvalol, they must adhere to a certain dosage. In this case, doctors do not recommend taking more than 15 drops. Exceeding the dosage may result in fainting.
In what cases can Corvalol be taken as an antihypertensive drug?

It is allowed to take the drug to lower blood pressure in the following cases:
If high blood pressure caused by stress;
if high blood pressure is associated with vasospasm;
if your blood pressure has increased due to lack of sleep.
How to take Corvalol to lower blood pressure?
Drops are drunk one to three times a day before meals. To do this, dilute 30 drops in 50 ml warm water and drink in one gulp. After about half an hour, the pressure will drop and improvement will occur. If necessary, the dosage can be increased as prescribed by the doctor and amount to 40 drops.

If the drug is in tablets, you should take one or two tablets twice a day.
Doctors categorically do not recommend taking this medicine for hypertension in long courses. Its use is justified only if there is an urgent need to reduce blood pressure, but the person does not have the drug that the person usually takes with him.

If you still have to take it, you need to take breaks or alternate with other drugs of the same effect. Doctors are categorically against the use of Corvalol as a means of preventing hypertension.
Why is it dangerous?
Nowadays, the attitude in the world towards this drug is ambiguous. It is banned in some countries.

Corvalol is available in Russia, but doctors advise caution when using it. The fact is that taking it for a long time can lead to addiction. With regular use, a person may experience a bad reaction, dizziness, lethargy, constant drowsiness, nausea, short-term losses consciousness. It contains phenobarbital, which has hypnotic effect, therefore Corvalol should not be taken by people whose activities are associated with increased concentration.
The benefits of Corvalol
Despite some negative effects, the drug has and useful qualities, among which are the following:

Corvalol relieves heart pain and promotes falling asleep quickly, deep and restful sleep.
It quickly eliminates emotional stress and panic state, relieves irritability, palpitations, anxiety and excitement, helps with stress.
Eliminates pain during intestinal spasms and relieves their manifestations.
It helps with headaches, so people suffering from this pathology take it in addition to the main pills.

Conclusion
Corvalol is a well-known, accessible and inexpensive drug. This makes it very popular for use in different situations related to nervous tension and various experiences with disturbances in the functioning of the cardiovascular system, including increased blood pressure.

Despite the fact that the drug helps lower blood pressure, it is not recommended to abuse it. There are many ways to treat hypertension effective means, the choice of which is individual and is within the competence of the cardiologist.

People who live in modern world, it is very difficult to avoid stressful situations. Many women and men experience irritability and suffer from neuroses. As a result, it gets worse general state, lethargy, insomnia, spasms, tachycardia appear, fatigue and blood pressure increase. It is important to monitor your health and use special sedatives in a timely manner. One of them is Valocordin - a sedative that is prescribed for disorders of the nervous system and the presence cardiovascular diseases.

Composition of Valocordin

The drug is available in two dosage forms. Valocordin drops look like clear liquid with a strong aromatic odor. They can be purchased in glass dropper bottles of 20 and 50 ml, packaged in cardboard boxes. More depressant produced in the form of regular and soluble tablets(10 pieces per blister).

The composition of Valocordin looks like in the following way:

Action of Valocordin

Drops and tablets are a combined medication, the therapeutic effect of which is based on pharmacological properties constituent elements. Valocordin contains ethyl bromoisovalerianate (ethyl ester of α-bromoisovaleric acid) and phenobarbital. These components have a hypnotic or sedative effect on the body, which depends on the dosage. Phenobarbital is a derivative of barbiturate acid; the substance inhibits the inhibitory system of the reticular formation. Ethylbromoisovalerate provides a sedative and antispasmodic effect.

Phenobarbital is absorbed very actively in the stomach. Next, 35% of the substance is bound by blood plasma proteins, and the rest is filtered in the kidneys. Reabsorption (reabsorption of fluid) occurs at a low pH level. Approximately 30% of phenobarbital is excreted unchanged from the body in the urine, the remainder of the substance is oxidized by the liver. If Valocordin is used long time, then the active component accumulates in the plasma, and induction of liver enzymes also occurs. The oxidation procedure of phenobarbital is activated.

Indications for use

There are a number of conditions and diseases for which a sedative is prescribed. Instructions for use of Valocordin include the following indications:

• insomnia, sleep dysfunction;
• headache(migraine);
• flatulence ( complex therapy);
• sudden attacks angina pectoris (chest pain);
• neuroses;
• painful sensations in the area of ​​the heart (for example, cardialgia), caused by spasm of the coronary vessels;
• psycho-emotional overexcitation, which is provoked stressful situation;
• spasms of the gallbladder and intestines (if there is no obstruction of these organs);
• stage 1 hypertension (frequent and persistent increase in blood pressure).

How to take Valocordin

According to the instructions, drops or tablets are taken orally. The dosage and duration of taking the medicine are prescribed by the doctor on an individual basis. Approximate average dosage drops:

• high blood pressure, nervousness: 15-20 drops two to three times a day before meals, wash down with a small amount of water;
• tachycardia, pain in the heart area: 30-40 drops twice a day, washed down with sweet tea or water;
• children from 14 to 18 years old 1-2 times a day, 3-8 drops.

Sometimes Valocordin is prescribed in tablets. The dosage is as follows dosage form as follows:

• single dose: 15-25 mg per day;
• for the treatment of allergy symptoms: 25 mg every 4-6 hours (no more than 150 mg per day);
• children from 6 to 12 years: 6.25-12.5 mg every 6 hours.

special instructions

To avoid adverse reactions and not to worsen your health, it is necessary to study special instructions on the use of Valocordin. Main features you should know when using the medication:

The drops contain 55% ethyl alcohol(ethanol).

When a person, for a long time taking phenobarbital, abruptly stops the course of treatment, then he may develop withdrawal syndrome (accompanied by convulsions, delirium, probable death).

The substance phenobarbital can cause addiction. Physical and psychological dependence may appear when long-term use drops or tablets in large dosages. If the body quickly becomes accustomed to the active component, then the dose for effective therapy rises.

Patients with acute or chronic pain Phenobarbital should be taken with caution. This is due increased risk the occurrence of paradoxical arousal and masking of serious clinical signs.

Chronic poisoning sedative may cause irritability, sleep disturbance, confusion, and somatic problems. The symptoms of an overdose are similar to those of a chronic form of alcoholism.

Valocordin during pregnancy

The drug should not be taken during pregnancy. Phenobarbital, which is contained in Valocordin, can cause delayed development of the fetus, and ethanol can provoke the development of birth defects, anomalies, and even serious damage to the internal organs of the embryo. During lactation ( breastfeeding) the use of sedative medication is also contraindicated. Its active elements are able to penetrate into breast milk, and with it enter the newborn’s body. As a result, severe poisoning and depression of the central nervous system (CNS) develops.

Drug interactions

The instructions for use describe the interaction of the drug with other medications. During the therapy process, the following points should be taken into account:

1. If you use drops simultaneously with other sedative medications, antipsychotics and tranquilizers, the effect of phenobarbital is significantly enhanced.
2. The active component may reduce the effectiveness oral medications contraception, griseofulvin and coumarin derivatives, glucocorticosteroids.
3. If you use antipsychotics and tranquilizers with central nervous system stimulants, the effect of phenobarbital is reduced.
4. Alcohol can increase medicinal effect Valocordin, increasing the toxicity level of the droplets.
5. Doctors do not recommend taking phenobarbital with drugs whose metabolism occurs in the liver. Part of the components sedative may accelerate hepatic metabolism and increase the concentration of Valocordin's constituent substances.

Side effects

In most cases, Valocordin is normally tolerated by the human body. If the dosage of the drug is not observed, personal intolerance to the drug and other reasons may cause side effects:

1. Respiratory system: apnea (stop breathing movements), hypoventilation (lack of oxygen for tissues and organs).
2. Digestive system: attacks of nausea, vomiting, constipation.
3. Nervous system: mental disorders, agitation, anxiety, confusion, insomnia or drowsiness, ataxia (loss of coordination), hallucinations, nervousness, depression of central nervous system functions.
4. Cardiovascular system: decreased blood pressure, bradycardia (slow heart rate), dizziness, fainting.
5. Development of anemia (decrease in hemoglobin concentration) with long-term use of Valocordin. For the same reason, chronic bromine poisoning can occur with the following symptoms: apathy, hemorrhagic diathesis, impaired coordination of movements, rhinitis, depression, conjunctivitis.

Overdose

If you take Valocordin for a long period of time and do not follow the permitted dosage, health problems may arise. Main symptoms of overdose:

• weakness;
• bradycardia (sudden slowing of heart rate);
• apathy;
• difficulty breathing, lack of oxygen;
• psychomotor disorders;
• intoxication of the body;
• dizziness, fainting;
• vascular collapse, impaired reflexes;
• a sharp decrease in blood pressure.

Contraindications

In some cases, therapy with Valocordin is prohibited. Contraindications described in the instructions for the drug:

• age category up to 14 years old;
• acute myocardial infarction;
• liver and kidney failure;
• brain diseases;
• traumatic brain injuries;
• individual intolerance to the drug;
• alcoholism;
• pregnancy, breastfeeding;
• cardiogenic shock.

Terms of sale and storage

You can buy a sedative at any pharmacy without a prescription. Drops or tablets must be stored out of the reach of children, at a temperature of no more than 15º C. The shelf life of the sedative is 5 years.

Analogs

When a patient cannot be treated with Valocordin for a number of reasons, the doctor prescribes analogue drugs. It is often replaced with the following drugs:

Valecard - drops with a sedative effect. They are prescribed for neuroses, functional lesions of the cardiovascular system, and states of severe nervous excitement.

When used correctly, the drug Barboval has antispasmodic, sedative, hypotensive effect. The solution effectively relaxes muscles and eliminates flatulence (bloating).

Another analogue of Valocordin is Corvalol tablets and drops. This drug gives a pronounced antispasmodic and sedative effect.

Corvaldin is a solution that restores normal sleep, calms the nervous system, relieves spasms.

Corvaltab tablets work well against insomnia, help reduce the excitability of the central nervous system, and have a sedative effect.

Corvalcaps are capsules that are prescribed for tachycardia, minor spasms of the coronary vessels, neuroses with high irritability, vegetative-vascular dystonia, insomnia.

Valocordin price

You can purchase the drug in almost every pharmacy in Moscow and the region. You can also order it from the online store at an affordable price (there are promotions and discounts). approximate cost funds are presented in the table.