Furazolidone suppositories. Terms of sale in the pharmacy chain
Name:
Furazolidone (Furazolidonum)
Pharmacological
action:
Furazolidone – antibacterial medicine nitrofuran groups. Furazolidone is a synthetic derivative of 5-nitrofurfurol, which has a pronounced antimicrobial activity against gram-negative aerobic microorganisms, gram-positive aerobic microorganisms, some protozoa and fungi (in particular, fungi of the genus Candida) are less sensitive to the action of the drug.
pharmachologic effect drug directly depends on the dose, when using low doses, furazolidone has a bacteriostatic effect, with an increase in the dose, a pronounced bactericidal activity is noted. In addition, the drug has some immunostimulating effect. The mechanism of the antimicrobial action of the drug lies in the ability of the nitro group of furazolidone to be restored to the amino group under the action of bacterial enzymes. Substances formed as a result of the reduction of the nitro group have toxic effect, block the row biochemical processes in a bacterial cell, violate the structure and integrity of the cell membrane. In particular, when using furazolidone, an irreversible blockade of NADH and inhibition of the tricarboxylic acid cycle are noted, as a result of which the cellular respiration of microorganisms is disturbed, the function cytoplasmic membrane and death of the microorganism occurs. The furazolidone molecule, due to the ability to form complex compounds with nucleic acids, disrupts the synthesis of a number of proteins in a bacterial cell, as a result of which the growth and reproduction of microorganisms is inhibited.
The mechanism of immunostimulatory action the drug lies in its ability to increase the complement titer and the phagocytic activity of leukocytes. In addition, furazolidone reduces the production of toxins by microorganisms, resulting in an improvement in the overall clinical picture noted earlier than microbiological tests give negative result.
The ability of furazolidone to inhibit monoamine oxidase was noted, which leads to lung development excitement in patients taking this drug. Furazolidone increases the body's sensitivity to ethyl alcohol, which can lead to the development of nausea and vomiting when simultaneous use alcohol and furazolidone.
The drug is effective in therapy infectious diseases caused by strains of microorganisms sensitive to the action of furazolidone, including:
Gram positive and Gram negative aerobic bacteria
: Streptococcus spp., Staphylococcus spp., Shigella spp. (including Shigella dysenteria, Shigella boydii, Shigella sonnei), Salmonella typhi, Salmonella paratyphi, Esherichia coli, Proteus spp, Klebsiella spp, and bacteria of the genus Enterobacter.
The drug is also effective against protozoa, including Trichomonas spp., Lamblia spp.
In addition, the drug is effective against fungi of the genus Candida, however, before prescribing furazolidone for the treatment of candidiasis, sensitivity tests should be performed.
Microorganisms causing anaerobic and purulent infections are practically insensitive to furazolidone.
Drug resistance develops slowly.
After oral administration the drug is rapidly absorbed in the gastrointestinal tract. In plasma, therapeutically significant concentrations of the drug are observed within 4-6 hours after oral administration. In patients suffering from meningitis, the concentrations of furazolidone in the cerebrospinal fluid correspond to those in the blood plasma. After absorption, the drug is rapidly metabolized in the body, mainly in the liver, with the formation of a pharmacologically inactive metabolite. Due to the rapid metabolism of the drug, it is not noted therapeutically significant concentrations furazolidone in the blood and tissues (including the kidneys). It is excreted mainly by the kidneys, both unchanged and as a pharmacologically inactive metabolite. High therapeutic concentrations of the drug are observed in the intestinal lumen.
In patients suffering from kidney failure, there is an accumulation of the drug in the body due to a decrease in the rate of its excretion by the kidneys.
Indications for
application:
The drug is used for treatment of patients with infectious diseases of organs gastrointestinal tract, genitourinary system, as well as skin, in particular:
Bacillary dysentery, typhoid, paratyphoid, enterocolitis, giardiasis, diarrhea infectious etiology. The drug is also used to treat food poisoning.
Trichomonas infection, including trichomonas colpitis, as well as vaginitis, urethritis, cystitis and pyelitis.
The drug is used to treat patients with infected wounds and burns.
Mode of application:
The drug is taken orally. The tablet is recommended to be swallowed whole, without chewing or crushing, with big amount water. The drug should be taken after meals. The duration of the course of treatment and the dose of the drug is determined by the attending physician individually for each patient, depending on the nature of the disease and the patient's personal characteristics.
Adults for the treatment of dysentery, paratyphoid and food toxic infections are usually prescribed 0.1-0.15 g (2-3 tablets) of the drug 4 times a day. The duration of the course of treatment, depending on the severity of the disease, is from 5 to 10 days. The drug can also be taken in cycles of 0.1-0.15 g 4 times a day for 3-6 days, after which they take a break for 3-4 days and resume taking the drug according to the same scheme.
Adults for the treatment of giardiasis usually prescribed 0.1 g (2 tablets) of the drug 4 times a day.
Adults for the treatment of Trichomonas urethritis are usually prescribed 0.1 g (2 tablets) of the drug 4 times a day. The duration of the course of treatment is 3 days.
Adults for the treatment of trichomonas colpitis usually prescribed 0.1 g (2 tablets) of the drug 3-4 times a day orally in combination with drugs containing furazolidone, in the form of vaginal and rectal suppositories. Duration general course treatment 1-2 weeks, the duration of oral administration of the drug in complex therapy is 3 days.
Maximum single dose for adults is 0.2 g of the drug (4 tablets), daily - 0.8 g (16 tablets).
Children for the treatment of dysentery, paratyphoid and food poisoning the dose is determined depending on age and body weight. Maximum duration course of treatment is 10 days.
Children for the treatment of giardiasis usually prescribe the drug at 10 mg / kg of body weight per day. The daily dose should be divided into 3-4 doses.
For treatment infected wounds and burns the drug is prescribed in the form of irrigation or wet-drying dressings, having previously prepared a solution of furazolidone with a concentration of 1:25000.
Side effects:
The drug is of low toxicity, however, in some cases, side effects may develop during furazolidone therapy, including:
From the gastrointestinal tract: anorexia, nausea, vomiting, pain in the epigastric region.
allergic reactions: skin rash, itching, urticaria, angioedema.
To reduce the severity of side effects, it is recommended to drink the drug with plenty of water, as well as take B vitamins and antihistamines. With pronounced side effects, the drug should be stopped and contact your doctor.
At long-term use drug possible development of hemolytic anemia and methemoglobinemia (mainly in newborns and infants), as well as shortness of breath, cough, hyperthermia and neurotoxic reactions.
Contraindications:
Increased individual sensitivity to the components of the drug.
A drug contraindicated in patients with end-stage chronic renal failure.
The drug is not used to treat children under the age of 1 month.
Due to the fact that the drug contains milk sugar (lactose), it should not be prescribed to patients with glucose-6-phosphotdehydrogenase deficiency and lactase deficiency.
The drug should be used with caution in women during pregnancy and lactation, as well as in patients with impaired renal function.
The drug is prescribed with caution to patients suffering from diseases of the liver and nervous system.
The drug should not be prescribed to patients whose work is related to driving and potentially dangerous mechanisms.
Interaction
other medicinal
by other means:
At simultaneous application drug with drugs that change the pH of urine, there is a change in the rate of excretion of furazolidone. Thus, drugs that change the pH of urine to the alkaline side increase the excretion of furazolidine and reduce its effectiveness, and drugs that change the pH of the urine to the acid side reduce the rate of excretion of furazolidone and enhance its pharmacological action.
With the simultaneous use aminoglycosides and tetracycline contribute to strengthening pharmacological effects furazolidone.
With the combined use of the drug with chloramphenicol and ristomycin increased inhibition of hematopoiesis.
With the simultaneous use of furazolidone With ethyl alcohol
development of disulfiram-like reactions is noted.
A drug not prescribed concomitantly with antidepressants, monoamine oxidase inhibitors, ephedrine, amphetamine, tyramine and phenylephrine due to the risk of developing hypertensive reactions.
Pregnancy:
The drug during pregnancy should take strictly as directed by your doctor, which must carefully weigh the expected benefits to the mother and the potential risks to the fetus.
If necessary, the use of the drug during lactation should decide on a possible interruption breastfeeding, since furazolidone penetrates into breast milk and can cause the development of hemolytic anemia and methemoglobinemia in infants.
Overdose:
When using high doses of the drug patients may development toxic lesions liver, including acute toxic hepatitis. In addition, polyneuritis may develop ( neurotoxic effect) and the hematotoxic effect of furazolidone.
There is no specific antidote. In case of an overdose of the drug, gastric lavage, intake of enterosorbents and saline laxatives are indicated. If necessary, take measures to maintain water and electrolyte balance. It is also possible to assign antihistamines and B vitamins.
In case of severe drug overdose, as well as when using excessive doses of the drug in patients suffering from impaired renal function, hemodialysis is indicated.
Release form:
Tablets of 10 pieces in blister-free packaging.
Tablets of 10 pieces in a blister pack, 2 blister packs in a carton box.
1 tablet contains:
Furazolidone - 0.05 g;
Excipients, including lactose.
Sulfanilamides are powders based on sulfanilic acid. For improvement therapeutic effect they can be used with antibiotics. The drugs in this group include streptocide, inhalipt, ftalazol and others. These drugs are effective in the treatment of various coccal infections, cholera and viral diseases, as well as infectious diseases of the gastrointestinal tract.
Nitrofurans are used to treat infections caused by various cocci, some viruses, as well as Trichomonas and Giardia. The drugs in this group include furatsilin, furazolidone, fastin and others.
Furazolidone and other drugs of the nitrofuran group are effective means in the treatment of bacteria resistant to antibiotics and sulfa drugs.
Antibiotics have the ability to reduce the viability of microbes and disrupt their metabolism. However, many bacteria rapidly develop antibiotic resistance, especially when it is long-term use. Because of this, antibiotics are often ineffective against large numbers of bacteria. Then furazolidone and other drugs of the nitrofuran group come to their aid, the addiction to which bacteria develops extremely slowly. Particularly well-known antibiotics are penicillin, streptomycin, tetracycline, chloramphenicol, as well as a bactericidal patch, which we have known since childhood.
The main rule for taking furazolidone is that this medicine should not be prescribed to newly born children. If the child is more than 30 days old, then the drug can be used in antibiotic therapy without the risk of complications.
Also, this drug is not prescribed for patients with chronic diseases kidneys and liver.
Furazolidone, like other drugs, has a number of side effects. To prevent them, the drug is washed down with plenty of water and taken after meals. For the same purposes, it is recommended to use it for a maximum of ten days. When discomfort you must stop taking the drug and consult a doctor. Instead of completely stopping the drug, you can simply reduce its dosage.
Dysentery and paratyphoid are treated for no more than one week, after which a person's well-being improves. If this does not happen, the therapy is carried out in courses - furazolidone is taken for several days, then a break for several days. The scheme of taking the drug can only be developed by the attending physician.
It should be taken 100-150 mg of the drug 4 times a day, not exceeding the maximum daily dose in 800 mg.
Treatment can only be prescribed by a doctor, depending on the presence or absence of other bacteria in the human body and other factors. If treatment is not started on time, trichomoniasis can take a chronic form.
A feature of the treatment of trichomoniasis is that antibiotics are applied topically. When taking oral antibiotics, you may experience side effects, among which are unpleasant disease like a milkmaid. Therefore, the most effective therapy trichomoniasis is a combination local antibiotics and furazolidone, which does not cause such side effects, is a low-toxic antimicrobial drug and is effective in the treatment of those bacteria that have already developed resistance to most antibiotics.
For treatment, furazolidone can be used both orally and topically. Inside it is used 100 mg 3-4 times a day for 3 days. Local treatment longer and takes from seven to fourteen days. For the treatment of trichomoniasis, furazolidone is available in powder, which is injected into the vagina, and in suppositories, which are administered rectally.
Furazolidone is an antimicrobial drug that is effective in treating a variety of microbes, even resistant to antibiotics. It is most effective in the treatment of dysentery bacillus, Trichomonas and Giardia. This drug does not provide toxic effect on the human body, such as furatsilin. Therefore, the drug can be used in children from 1 month. In the first days of life, it is not recommended to prescribe this medicine, since the baby has not yet developed an enzyme system.
Another advantage of furazolidone is that bacteria develop resistance to it extremely slowly, which makes it possible to use this drug in the fight against a large number of various kinds bacteria.
Furazolidone is also used in the treatment chronic form alcoholism, if other drugs have not had the desired effect. When taking this drug, the patient gradually develops an aversion to alcohol.
When prescribing the drug to patients with alcoholism, it should be borne in mind that this drug can cause certain side effects in them, which are especially pronounced when taking alcohol. There may be a burning sensation throughout the body, heat, squeezing the head in its occipital part. Tachycardia and decreased blood pressure. On the one hand, these phenomena side effect taking furazolidone. On the other hand, it is these phenomena that cause a feeling of disgust for alcohol in the patient.
In case of impaired renal function, it is necessary to prescribe this drug with caution, and in chronic renal failure it should not be taken at all.
Nitrofurans - group antibacterial drugs intended for the treatment acute lungs forms of intestinal infections, infections urinary tract, trichomoniasis and giardiasis. Bacteria rarely develop resistance to these drugs.
Furazolidone and other drugs of the nitrofuran group are effective against most gram-positive and gram-negative bacteria and some fungi, such as candida. This drug is also effective in the treatment of the simplest microorganisms - Giardia and Trichomonas.
Side effects when taking furazolidone and other drugs of the nitrofuran group may be as follows. From the gastrointestinal tract - nausea, diarrhea, vomiting. On the part of the liver, hepatitis and cholestasis can be observed.
From the side skin- urticaria, muscle pain. On the part of the lungs, false pneumonia may occur with cough and pain in the chest. May also respond to the drug nervous system and the circulatory system, so dizziness may occur, headache, weakness, anemia, drowsiness, leukopenia.
Nitrofurans are contraindicated for newborns and pregnant women in the third trimester of streptococci, staphylococci and others), as well as those types of bacteria that have developed resistance to antibiotics and sulfanilamide drugs. Between themselves, the preparations of the nitrofuran group differ in their scope of action. So, furatsilin is used to treat gram-positive and gram-negative bacteria, furazolidone - from gram-negative bacteria, Giardia and Trichomonas, etc.
Nitrofurans are used both internally and externally as antiseptics. Inside the drugs of this group are prescribed for gastrointestinal intestinal infections and infections of the genitourinary system. At serious illnesses heart, liver and kidneys, as well as allergies to the components of a particular drug, furazolidone, furatsilin and others similar drugs are not assigned.
Consider some drugs of the nitrofuran group.
Furazolidone is used for intestinal infections such as dysentery, paratyphoid, food toxic infections, as well as for trichomoniasis and giardiasis. For intestinal infections and giardiasis, this drug is taken orally after meals, 100-150 mg 4 times a day for 5-10 days. Children's doses are adjusted depending on the age of the child. In the treatment of trichomonas vaginitis, this drug is used orally at 100 mg 3-4 times a day for 3-4 days. In parallel, the powder of this drug is injected into the vagina, suppositories are injected rectally. Local treatment is carried out for 7-14 days.
In this medical article, you can get acquainted with the drug Furazolidone. The instructions for use will explain in which cases you can take pills, what the medicine helps with, what are the indications for use, contraindications and side effects. The annotation presents the form of release of the drug and its composition.
In the article, doctors and consumers can only leave real reviews about Furazolidone, from which you can find out whether the medicine helped in the treatment of dysentery, toxic infections and associated diarrhea (diarrhea) in adults and children, for which it is also prescribed. The instructions list the analogues of Furazolidone, the prices of the drug in pharmacies, as well as its use during pregnancy.
An antibacterial drug from the group of nitrofurans is Furazolidone. Instructions for use for adults and children prescribe to take 50 mg tablets for the treatment of infectious pathologies.
Release form and composition
Furazolidone is available in tablet form. yellow color, flat-cylindrical with a chamfer on one side, 10 pieces in a contour package (2-3), in a cardboard box. Also, tablets can be packed in cans of polymeric material of 50 pieces. Attached to the drug detailed instructions with a description of the features.
Each tablet of the drug Furazolidone contains 50 mg of the same name active component, as well as a number of excipients.
pharmachologic effect
Furazolidone - an antibiotic or not? It is not an antibiotic. It's synthetic antibacterial agent a derivative of 5-nitrofurforol, which differs from true antibiotics by the mechanism of action on microorganisms and the effect on the human body.
The drug is effective in the treatment inflammatory diseases caused by Gram-negative aerobic bacteria. Gram-positive aerobic bacteria are less sensitive to it, as are fungi and protozoa.
Anaerobic pathogens are insensitive to Furazolidone. The pharmacological action of this drug depends on the dosage. At low doses, the drug has a bacteriostatic effect, and with an increase in doses, it has a bactericidal effect. Antimicrobial action is based on the fact that the nitro groups that make up the drug are reduced to amino groups under the influence of enzymes of microorganisms and become toxic to them.
The resulting amino groups are capable of violating the integrity cell membranes bacteria and block many processes in them. The result of such exposure is the loss of the ability of microorganisms to reproduce. Furazolidone has a slight immunostimulatory effect. This drug is able to increase the phagocytic activity of leukocytes and compliment titer.
What helps Furazolidone (tablets)?
Indications for the use of the drug include:
- cystitis;
- pyelitis;
- cholera;
- dysentery;
- local treatment of infected wounds and burns;
- giardiasis;
- paratyphoid;
- trichomonas colpitis and urethritis;
- food poisoning.
Instructions for use
Furazolidone is prescribed for adults with dysentery, paratyphoid, food poisoning 50-150 mg 4 times a day for 5-10 days. In children, doses are reduced according to age.
- At Trichomonas urethritis- 100 mg 4 times a day for 3 days.
- With giardiasis for adults - 100 mg 4 times a day; children - 10 mg / kg per day in 3-4 doses.
Maximum doses for adults: single - 200 mg, daily - 800 mg.
Contraindications 
- Lactose and glucose-6-phosphotdehydrogenase deficiency.
- Individual hypersensitivity to the drug Furazolidone, from which these tablets can cause side effects.
- End-stage chronic renal failure.
- The child is less than one month old.
Side effects
During treatment with Furazolidone in individuals with increased individual sensitivity to nitrofurans, the following side effects may develop:
- severe thirst, nausea, stomach pain, sometimes vomiting, anorexia, pain in the right hypochondrium, cholestatic jaundice, abnormal liver function, diarrhea, bloating;
- pain in chest, shortness of breath, dry cough, exacerbation of seizures bronchial asthma in asthmatics, the development of bronchospasm;
- headaches, dizziness, drowsiness, lethargy, tremor of the extremities, polyneuropathy, irritability, aggression;
- Quincke's edema, skin itching, urticaria, skin redness, dermatitis;
- leukopenia, thrombocytopenia, agranulocytosis, hemolytic anemia, megaloblastic anemia (these phenomena are temporary and quickly passing).
In some cases, flu-like symptoms may develop - joint and muscle pain, chills, fever.
Children, during pregnancy and lactation
The use of Furazolidone during pregnancy and lactation is possible only under the supervision of doctors and after a complete analysis of the possible risks to the fetus / child and the benefits to the woman.
Not used to treat children under one month of age. The drug is prescribed with caution to children under the age of 3 years.
special instructions
Use with caution in patients with severe impaired renal function, deficiency of glucose-6-phosphate dehydrogenase, in children under the age of 1 month. Furazolidone is an MAO inhibitor and appropriate precautions should be taken when using it.
The drug has the ability to sensitize the body to the action of ethanol (alcohol) and can be used to treat alcoholism. Because of the danger arterial hypertension And mental disorders it is recommended to exclude from the diet foods rich in tyramine (cheese, chocolate, etc.).
drug interaction
Tetracyclines and aminoglycosides increase antibacterial activity medication. At simultaneous reception Furazolidone and Ristomycin, Chloramphenicol increases the risk of inhibition of hematopoietic function.
The drug should not be administered simultaneously with Amphetamine, Ephedrine, MAO inhibitors, because. it's connected with high risk development of a hypertensive reaction.
Furazolidone's analogs
Analogues have a similar effect: 
- Nifuroxazide.
- Fluoroquinolone.
- Amikacin.
- Imipenem.
- Rifaximin.
- Entprofuril.
Holiday conditions and price
The average price of Furazolidone (tablets 50 mg No. 20) in Moscow is 110 rubles. Released without a prescription.
Store in a dry, dark place and out of the reach of children. Shelf life - 3 years.
Antibacterial drug, a derivative of nitrofuran
Active substance
Furazolidone (furazolidone)
Release form, composition and packaging
◊ Pills yellow or greenish-yellow, flat-cylindrical, with a chamfer.
Excipients: potato starch - 20 mg, calcium stearate (calcium stearate) - 1 mg, sugar (sucrose) - 10 mg, tween-80 (polysorbate) - 0.2 mg, lactose (milk sugar) - 18.8 mg.
10 pieces. - packings without cell contour.
10 pieces. - blister packs (2) - cardboard packs.
10 pieces. - blister packs (3) - cardboard packs.
10 pieces. - blister packs (4) - cardboard packs.
10 pieces. - blister packs (5) - cardboard packs.
50 pcs. - polymer cans (1) - packs of cardboard.
pharmachologic effect
- deficiency of glucose-6-phosphate dehydrogenase;
— childhood up to 3 years (for this dosage form).
Carefully
Chronic kidney failure, deficiency of glucose-6-phosphate dehydrogenase, diseases of the liver and nervous system.
Dosage
Inside, after eating.
At dysentery, paratyphoid and food poisoning- 100-150 mg 4 times / day (but not more than 800 mg), for 5-10 days.
With giardiasis: adults- 100 mg 4 times / day, children- 10 mg / kg / day, distributing the daily dose into 3-4 doses.
The highest single dose for adults is 200 mg; daily - 800 mg.
Side effects
Decreased appetite, up to anorexia; nausea, vomiting; allergic reactions(skin rash, hyperemia and itching of the skin, angioedema).
With prolonged use - neuritis.
Overdose
Symptoms: spicy toxic hepatitis, hematotoxicity, neurotoxicity (polyneuritis).
Treatment: cancellation of drugs, acceptance a large number liquid, symptomatic therapy, antihistamine drugs, group B.
drug interaction
Furazolidone in combination with ethanol can lead to the development of disulfiram-like reactions, and therefore their simultaneous administration is not recommended. Antidepressants, monoamine oxidase inhibitors, amphetamine, phenylephrine, tyramine can cause sharp rise HELL.
special instructions
Increases sensitivity to the action of ethanol.
Medicines that alkalinize urine reduce the effect, while acidifiers increase it.
Aminoglycosides and enhance antimicrobial properties.
In this article, you can read the instructions for use medicinal product Furazolidone. Reviews of site visitors - consumers are presented this medicine, as well as the opinions of medical specialists on the use of Furazolidone in their practice. We kindly ask you to actively add your reviews about the drug: the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Furazolidone analogues, if available structural analogues. Use for the treatment of dysentery, toxic infections and associated diarrhea (diarrhea) in adults, children, as well as during pregnancy and lactation.
Furazolidone- the drug belongs to antimicrobial and antiprotozoal agents. It has a bacteriostatic effect against microbes. The mechanism of action is to disrupt the activity of certain enzyme systems of bacteria. Spectrum of action: gram-positive cocci (Streptococcus, Staphylococcus), gram-negative rods (Escherichia, Salmonella, Shigella, Proteus, Klebsiella, Enterobacter), protozoa (Lamblia).
Of the causative agents of intestinal infections, the causative agents of dysentery are most sensitive, typhoid fever and paratyphoid. Resilience develops slowly.
Pharmacokinetics
At oral administration furazolidone is poorly absorbed and inactivated in the intestine. Only about 5% of the drug is excreted from the body in the urine unchanged or as metabolites, while staining the urine brown.
Indications
- dysentery;
- paratyphoid;
- food poisoning;
- giardiasis.
Release form
Tablets 50 mg.
Instructions for use and dosage
With dysentery, paratyphoid, food poisoning in adults, apply 50-150 mg 4 times a day for 5-10 days. In children, doses are reduced according to age.
With giardiasis for adults - 100 mg 4 times a day; children - 10 mg / kg per day in 3-4 doses.
With trichomonas urethritis - 100 mg 4 times a day for 3 days. Maximum doses for adults: single - 200 mg, daily - 800 mg.
Side effect
- nausea;
- vomit;
- loss of appetite;
- allergic reactions in the form of a skin rash.
Contraindications
- hypersensitivity to furazolidone.
special instructions
Use with caution in patients with severe impaired renal function, deficiency of glucose-6-phosphate dehydrogenase, in children under the age of 1 month.
Furazolidone is an MAO inhibitor and appropriate precautions should be taken when using it.
Furazolidone has the ability to sensitize the body to the action of ethanol (alcohol) and can be used to treat alcoholism.
Due to the risk of arterial hypertension and mental disorders, it is recommended to exclude foods rich in tyramine (cheese, chocolate, etc.) from the diet.
drug interaction
Means that alkalinize urine reduce the effect of furazolidone, acidifying agents increase it.
Simultaneous administration of aminoglycosides and tetracyclines enhances antimicrobial properties.
Furazolidone increases the inhibition of hematopoiesis against the background of chloramphenicol and ristomycin.
Analogues of the drug Furazolidone
Structural analogues according to active ingredient medicine Furazolidone does not have.
In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.
