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Description, release forms and composition

The drug Duspatalin is produced by the Dutch pharmaceutical corporation ABBOTT HEALTHCARE PRODUCTS, B.V., and is available in two dosage forms:
1. Tablets 135 mg.
2. Capsules 200 mg.

Duspatalin capsules contain a larger amount of active ingredient (200 mg) than tablets (135 mg). In addition, the capsules have a prolonged action, therefore the word “retard” is always written next to the name “Duspatalin”. It is the term “retard” that reflects the long-term effect of capsules compared to tablets. Capsules are also designated “Duspatalin 200”, based on the amount of active substance in their composition.

Duspatalin tablets are round in shape and colored white. Available in packs of 10, 15, 20, 30, 40, 50, 60, 90, 100 or 120 pieces. The capsules have a dense gelatin shell, colored opaque white. The capsules are marked "245", "S" and "7", and their contents are white colored granules. Duspatalin capsules are available in 10, 20, 30, 50, 60 or 90 pieces.

As an active ingredient, both capsules and tablets Duspatalin contain the chemical substance mebeverine. One capsule contains 200 mg of mebeverine, and one tablet contains only 135 mg. The auxiliary components of tablets and capsules are different. For ease of reference, the excipients of both forms of Duspatalin are shown in the table:

Trimedat instructions for use. Trimedat - detailed instructions for use, price, reviews, analogues

And excipients: corn starch, colloidal silicon dioxide, lactose, talc, magnesium stearate.

Release form

The medication is available in tablet form, in packages of 10, 20, 30 pieces.

pharmachologic effect

Myotropic antispasmodic regulating motor skills digestive system . The active substance acts on the enkephalinergic system of the intestine, regulates peristalsis . Trimebutine has an antispasmodic effect in hyperkinesis of smooth muscle tissue of the digestive tract, and in hypokinetic conditions it stimulates intestinal function.

The drug enhances peristalsis and promotes emptying stomach , reduces pressure on esophageal sphincter , acts throughout the intestine, enhances the response of the smooth muscle tissue of the large intestine to various food stimuli.

Author-compiler:- doctor, medical journalist Speciality:Cardiology, Functional diagnostics, Otorhinolaryngology

Education: Graduated from the Bashkir State Medical University with a degree in General Medicine. In 2011, she received a diploma and certificate in Therapy. In 2012, she received 2 certificates and diplomas in “Functional Diagnostics” and “Cardiology”. In 2013, she took courses on “Current issues in otorhinolaryngology in therapy.” In 2014, she completed advanced training courses in the specialty “Clinical Echocardiography” and courses in the specialty “Medical Rehabilitation”.

Experience: From 2011 to 2014 she worked as a therapist and cardiologist at the Municipal Budgetary Healthcare Institution Polyclinic No. 33 in Ufa. Since 2014, he has been working as a cardiologist and functional diagnostics doctor at the Municipal Budgetary Healthcare Institution Polyclinic No. 33 in Ufa.

NOTE! Information about medications on the site is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment. Before using the drug Trimedat, be sure to consult with your doctor.

Maya | 12:40 | 10.08.2018

I had colitis, although I endured the pain for a long time and did not go to the doctor. Where was my mind? I don’t know... I took the Trimedat course and forgot about the pain and discomfort in my stomach. And why not immediately go and resolve this issue? Don't repeat my mistakes!

Glasha | 18:46 | 28.04.2018

Good pills. I always take them on vacation so as not to spoil it. In ordinary life, I adhere to proper nutrition, but when I travel, especially in other countries, I allow myself slack, and somewhere I eat exotic dishes, and then I have stomach problems. And trimedat solves them all. It’s convenient that you don’t need to drink different products; one is enough to rest peacefully.

Marina | 13:27 | 10.04.2018

Trimedat helped me, they are good tablets and inexpensive. Now there are no hints of constipation.

Daria Ustinova | 12:18 | 19.01.2018

With my job, I eat normally once a day, but if I have snacks, I don’t have time to eat at all, and as a result, my stomach throws up surprises. I don’t have time to go to the doctors, I consulted with the pharmacist, she recommended taking trimedate as the instructions say. Did. It helped. I think that if I again have surprises from the stomach or intestines, I drink another course, it’s better than finding myself in an awkward position in society.

Olga | 21:39 | 02.08.2017

I didn’t know about this drug before, but when I encountered cramps and nausea, I went to the doctor, but on gastroscopy they didn’t find anything serious, but they told me to be careful because there was irritation. They prescribed me a diet and trimedat. A week later there were no more problems, but they ordered me to take a course and I took it for up to 30 days, 3 packs. Everything is normal now.

This page provides a list of all Trimedat analogues by composition and indication for use. A list of cheap analogues, and you can also compare prices in pharmacies.

  • The cheapest analogue of Trimedat:
  • The most popular analogue of Trimedat:
  • ATX classification: Trimebutine
  • Active ingredients/composition: trimebutine

Cheap analogues of Trimedat

When calculating the cost cheap analogs of Trimedat the minimum price was taken into account, which was found in the price lists provided by pharmacies

Popular analogs of Trimedat

The list of drug analogues based on statistics of the most requested drugs

All analogues of Trimedat

The above list of drug analogues, which indicates Trimedat substitutes, is the most suitable because they have the same composition of active ingredients and coincide in indications for use

Analogues by indication and method of use

Different composition, may have the same indication and method of use

Name Price in Russia Price in Ukraine
glycopyrronium bromide 918 RUR 1533 UAH
Otilonium bromide -- 7 UAH
Prifinium bromide -- 7 UAH
papaverine 6 rub 5 UAH
papaverine 6 rub 7 UAH
papaverine -- 7 UAH
papaverine -- 5 UAH
drotaverine 13 rub. 2 UAH
drotaverine 30 rub 7 UAH
drotaverine -- --
drotaverine 56 RUR 6 UAH
drotaverine -- 7 UAH
drotaverine 13 rub. 9 UAH
drotaverine -- 4 UAH
drotaverine -- 7 UAH
drotaverine 30 rub 7 UAH
drotaverine -- 12 UAH
drotaverine 61 RUR 92 UAH
drotaverine 54 RUR --
antibodies to human tumor necrosis factor alpha (TNF-a) affinity purified, antibodies to brain-specific protein S-100 affinity purified, antibodies to histamine affinity purified 27 rub. 455 UAH
serotonin adipate -- 1200 UAH
prucaloprid 1436 RUR 561 UAH
Calamus, St. John's wort, Wormwood, Chamomile, Licorice glabra -- 110 UAH
Coriander, Chamomile, Common fennel -- --
Common fennel 215 RUR 9 UAH
Cumin 41 rub. 6 UAH
Dill fragrant 28 rub. --
Common fennel 33 rub. 1 UAH
vinboron -- --
platyphylline hydrotartrate -- --
platyphylline hydrotartrate -- 35 UAH
platyphylline hydrotartrate -- 31 UAH
simethicone, phloroglucinol dihydrate -- 7 UAH
136 RUR --
-- --
dimethicone, guaiazulene 21 rub. 435 UAH
pinaveria bromide 12 rub. 89 UAH
simethicone -- 7 UAH
simethicone 72 rub. 7 UAH
simethicone 287 RUR 7 UAH
dimethicone 1860 rub. 7 UAH
silicones 61 RUR 301 UAH
simethicone -- 7 UAH
simethicone 1450 rub. 7 UAH
simethicone -- 7 UAH
simethicone 138 RUR 7 UAH
simethicone -- 7 UAH
simethicone -- 15 UAH
simethicone 98 RUR --
platiphylline 41 rub. 5 UAH
homeopathic potencies of various substances 521 RUR 7 UAH
angelica, iberis, lemon balm, mint, milk thistle, chamomile, licorice, caraway, celandine 5 rub 49 UAH
163 RUR 155 UAH
202 rub. 44 UAH
-- 7 UAH
alverine, simethicone 362 RUR 7 UAH

To compile a list of cheap analogues of expensive drugs, we use prices that are provided to us by more than 10,000 pharmacies throughout Russia. The database of drugs and their analogues is updated daily, so the information provided on our website is always up to date as of the current day. If you have not found the analogue you are interested in, please use the search above and select the medicine you are interested in from the list. On the page of each of them you will find all possible analogues of the drug you are looking for, as well as prices and addresses of pharmacies where it is available.

How to find a cheap analogue of an expensive medicine?

To find an inexpensive analogue of a medicine, a generic or a synonym, first of all we recommend paying attention to the composition, namely the same active ingredients and indications for use. The same active ingredients of a drug will indicate that the drug is a synonym for the drug, pharmaceutically equivalent or a pharmaceutical alternative. However, we should not forget about the inactive components of similar drugs, which may affect safety and effectiveness. Do not forget about the instructions of doctors; self-medication can harm your health, so always consult a doctor before using any medication.

Trimedat price

On the websites below you can find prices for Trimedat and find out about availability at a pharmacy near you
Due to its solubility in water, the drug is quickly absorbed when administered subcutaneously and intramuscularly. Does not cause the formation of infiltrates and complications (oleomas). Possible intravenous administration.

Indications for use
- acute cardiac and respiratory failure;
- cardiogenic and anaphylactic shock;
- to stimulate breathing in chronic respiratory and heart failure, pneumonia, infectious diseases.

Contraindications
Hypersensitivity to the components of the drug (including procaine), pregnancy, lactation, age under 18 years (efficacy and safety have not been established).
Carefully
Arterial hypotension.

special instructions
Caution should be exercised when administering the drug to patients with low blood pressure due to the possibility of developing the hypotensive effect of novocaine, released in the body from sulfocamphocaine.

Directions for use and doses
Subcutaneously, intramuscularly, 2 ml of a 10% solution, if necessary, the frequency of administration is up to 2 - 3 times a day.
In acute cases, the drug is administered intravenously (slowly in a stream or drip) in a single dose - 2.0 ml of a 10% solution.
For chronic respiratory and heart failure, pneumonia, infectious diseases, it is administered subcutaneously or intramuscularly. The maximum daily dose is 12 ml of a 10% solution (1.2 g). If necessary, the course of treatment can be 20-30 days. The duration of use is determined individually.

Side effect
Reduced blood pressure (especially in patients with initial arterial hypotension), dyspeptic disorders, allergic reactions.

Interaction with other drugs
Compatible with cardiac glycosides, steroid hormones, analgesics.

Release form
Injection solutions in ampoules.

Storage conditions
In a place protected from light at a temperature not exceeding 25 ° C.

Best before date
3 years.

All information is presented for informational purposes and is not a reason for independent prescription or replacement of medication.

Trimedat belongs to the group of myotropic antispasmodics, the action of which is aimed at regulating gastrointestinal motility. The pharmacological effect is manifested in the restoration of gastrointestinal motility, which occurs as a result of relaxation of muscle tissue. The drug is effective throughout
length of the gastrointestinal tract, as a result of which intestinal peristalsis improves, destroyed
the activity of his muscles. The international nonproprietary name (INN) is trimebutine, the country of origin is Korea, the packaging is produced in Moscow by the Valenta company. The drug is not an antibiotic; the conditions for use (information about the composition, indications and contraindications) can be found in the annotation, Wikipedia, in the photos and pictures you can see what the packaging looks like.

Indications for use

  • gastroesophageal reflux disease;
  • disorders due to gastrointestinal diseases;
  • dyspeptic disorders due to gastroduodenal diseases (indigestion, abdominal pain, vomiting, nausea);
  • irritable bowel syndrome;
  • postoperative paralytic intestinal obstruction, preparation for endoscopic and x-ray examinations of the gastrointestinal tract.

Trimedat is also prescribed for pancreatitis, flatulence, gastritis, biliary dyskinesia
ways, for diarrhea, high acidity, for diarrhea, for colitis, it is also recommended to take it for
constipation, nausea.

The drug is prescribed to a child for dyspeptic disorders caused by gastrointestinal motility disorders.

Composition, cost

The drug has two forms of release: tablets and suspension. The main active ingredient of the medicine is
trimebutine maleate, also contains the following auxiliary components: magnesium stearate, corn
starch, talc, colloidal silicon dioxide, lactose. Tablets are sold in cardboard boxes of 10, 20 and 30
cellular contour packages. How much does Trimedat cost? The cost depends on the number of tablets in the pack and varies between 165-405 rubles.

Trental analogues are cheaper

Is it possible to buy an analogue of the drug in pharmacies cheaper than what can be replaced? The medicine is cheaper
foreign and Russian analogues, one of them is motilak. Other analogues at the same or higher
cost: duspatalin, ganaton, meteospasmil, buscopan, duspatalin, dicetel, motilium, de-nol.

Instructions for use of trimedat for adults

The tablets must be swallowed and washed down with water; the dosage for children over 12 years of age and adults is 100-200 mg.
drug 3 r. per day. In order to prevent relapse of IBS after a full course of treatment during the period of remission, the medication should be continued, the dosage is 300 mg, the treatment period is 12 weeks. Dosage of suspensions - 2 tbsp. l. 3 r. in a day. How long is the treatment period, how many days? The duration of treatment in each specific case differs; in case of urticaria, the duration of treatment can take 2-6 weeks; the daily dosage can be increased to 450-600 mg.

For children dosage

Pills:

  • Children aged 5-12 years - 50 mg 3 times. in a day;
  • 3-5 years - 25 mg 3 times. in a day.

Suspensions:

  • over 5 years - 2 tsp. 3 r. in a day;
  • 1-5 years - 1 tsp. 3 r. in a day;
  • 0.5-1 g - 1 tsp. 2 rubles per day;
  • up to 0.5 g - 0.5 tsp. 2-3 r. in a day.

How to take it correctly for pancreatitis and flatulence?

How to take the drug for indications such as flatulence and pancreatitis? In such cases
complex therapy is used, since one dose often does not lead to the expected therapeutic effect, painful discomfort in the abdominal area is reduced only in some cases. Dosage
is selected individually depending on the severity of the condition and the age of the patient.

Should Trimedat be taken before or after meals?

How to take the drug correctly - before or after meals, instructions for use? Tablets recommended
drink within 15 – 30 minutes. before meals, at least within 20 minutes. after meal. It is recommended to take the medicine in
in a planned manner, throughout the entire course of treatment without interruptions. If you have symptoms of dyspepsia, you should take the tablets immediately, without focusing on meals.

Is it possible during pregnancy?

Is Trimedat prescribed during pregnancy, when can you drink it? The annotation states that during pregnancy from
Taking the drug should be avoided in the first three months, as well as during breastfeeding.

Trimedat reviews from doctors

What are the doctors' reviews? Feedback from experts is positive, which is due to certain factors; they base their opinion on the therapeutic effectiveness of the drug, the presence of contraindications, side effects and price. According to the listed characteristics, Trimedat is better than many similar medicines, so reviews about it are only positive. It helps in severe forms of the disease, has a convenient method of application, a person can buy it at any pharmacy.

Contraindications

The description of the medicine describes the conditions of use; it is not recommended to drink trimedate under the age of three; hypersensitivity to individual components is also a contraindication.

Side effects

The medication has no side effects with the exception of allergic reactions that may occur as a result of intolerance to individual components. There is no information on interactions with other drugs; diabetics should exercise caution since trimedate contains sugar. Taking two medications at the same time may increase their effect. An overdose can provoke increased side effects; if appropriate symptoms appear, therapy is carried out.

Trimedat and alcohol compatibility

Can it be taken simultaneously with alcohol? Compatibility with alcohol is not described, which means that their combination is allowed.

Trimedat instructions for use describe it as an antispasmodic drug used for the treatment of gastrointestinal diseases of the corresponding nature. Often people neglect the significance of this liner. And you should always familiarize yourself with its contents before purchasing the medicine. The essence of the description of the drug Trimedat: instructions for use, price, reviews of the drug, positive and negative, will be discussed below to help the potential buyer in choosing the remedy he needs.

General characteristics of the drug

The instructions call Trimedat an antispasmodic and a drug that regulates the motor function of smooth muscles to varying degrees throughout the gastrointestinal tract. To date, the medicine is produced by two companies. One of them, Russian, produces the product Trimedat Valenta. The second word is part of the name of the pharmaceutical manufacturer. The second is South Korean, producing simply Trimedat.

The visual difference between the products is the shape of the tablets. The medicine is not considered highly toxic, so its use is not permitted at an early stage of pregnancy. Reviews on Trimedat are varied, but positive ones prevail. The fact that for the drug Trimedat the price is in an affordable price range also adds points to the medicine.

How does the drug work?

The instructions for use characterize Trimedat as a regulator of peristalsis, which works universally in the case of a hypotonic state of various parts of the gastrointestinal tract and in the presence of spasms interfering with the digestion process. In this case, it is the speed and amplitude of motor motility of the digestive organs that is regulated. By normalizing muscle speed and strength, the drug allows the digestive system to move food along the tract in such a way that each of its elements has time to perform its assigned function in time. By stopping the manifestation of motor skills disorders, which make themselves felt in the form of:

  1. flatulence; colic;
  2. diarrhea; bloating;
  3. vomiting; spasms;
  4. nausea; various abdominal pains.

The therapeutic effect of the medication also lies in the fact that it eliminates the depressing and painful symptoms associated with disturbances in the functioning of the digestive system due to poor nutrition (overeating, eating fatty foods or spicy foods, and the like). Therefore, the drug is also used as a means to eliminate difficult tolerable manifestations of gastrointestinal disorders.

The drug Trimedat promotes the timely removal of digested food from the stomach and relieves tension in the esophageal sphincter, improving the functioning of the gastrointestinal tract

The medication ensures timely removal of the digested mass from the stomach and optimizes the tension of the esophageal sphincter. This integral effect leads to the elimination of reflux and, as a result, nausea and vomiting, as well as debilitating heartburn, disappear. Ultimately, it is clear that a huge advantage of the drug is the autoregulation of contractions of the muscular apparatus of the gastrointestinal tract, that is, the normalization of its motility, regardless of the direction of the pathological deviation.

Release forms

For Trimedat, tablets are so far the only dosage form that pharmaceutical manufacturers have mastered. Tablets are taken orally and have a dosage of 0.1 or 0.2 g. Tablets of the indicated dosages are packaged in blisters with quantities of 1, 2 and 3 dozen pieces. For the Russian medicine Trimedat tablets, the instructions for use are described as follows.

Their shape looks like a cylinder with a truncated cone in the form of a top. In other words, there is a chamfer on one side. The product with a lower dosage, on the plane opposite the cone, has two marks that intersect with each other. A product with a higher dosage has only one mark instead of two. Each tablet contains Trimedat, in addition to the active substance trimebutine in the form of trimebutine maleate, and also a standard set of excipients for tablet forms:

  • magnesium stearate - stabilizer and defoamer E-572;
  • colloidal silicon dioxide - silica, emulsifier E-551;
  • hydrous magnesium silicate (or talc);
  • lactose;
  • corn starch.

All this is needed to give the tablet a certain strength and to be able to compress it without losing its medicinal properties. Tablets with a lower dose of the South Korean medicine are easily recognized by the pressed combination of letters “TM” on one of the planes of the cylindrical surface. The second version of the imported tablet has a shape similar to a round shell with an embossed symbol on one of its surfaces. The symbol represents 2 drops. Before using any medication option, you should familiarize yourself with the situations in which it is not recommended.

Contraindications and side effects

This medicine, like other medicines, cannot always be used. For Trimedat tablets, the instructions for use prescribe the main contraindications in pediatrics, namely this medication is prohibited up to 12 years, Valenta - up to 3 years. In obstetrics, the drug is not prescribed during gestation before the 14th week. In addition, there are general contraindications:

  • lack of lactase;
  • GGM - inability of intestinal cells to absorb glucose and galactose (malabsorption);
  • allergy to the excipients present in the tablet or to trimebutine.

Since there is no information about whether the drug passes into human milk, it would be prudent not to use it during breastfeeding. If this cannot be done, then you will have to switch to artificial feeding of the child. The package insert mentions rare, isolated side effects. They can be expressed in menstrual irregularities and allergic manifestations, drowsiness and fatigue, abnormal bowel movements or anxiety.

When is the use of this medication indicated? What is the dosage of the medication for adults and children? Should Trimedat be used before or after meals? Such questions can often be heard on Internet forums. The drug Trimedat has the following indications for use:

  1. spontaneous reflux of gastric or duodenal masses into the esophagus (gastroesophageal reflux);
  2. dyspepsia - nutritional disorders due to dysfunction of the gastrointestinal tract;
  3. persistent functional disorders of the intestines, constant irritation;
  4. intestinal obstruction after surgery;
  5. preparation for examinations of the digestive system.

Before answering the question about how to take Trimedat before or after meals, you need to say how to take it in general:

  • tablets are not crushed;
  • take them orally without crushing or chewing;
  • You need to drink 100-150 ml of water.

The dosage of the drug in typical cases does not depend on the type of disease; the main differences are related to age:

  1. 100-200 mg taken three times a day is the norm for children starting from 12 years of age and adult patients;
  2. 75 mg is the norm for children from 3-6 years of age per day, divided into 3 doses;
  3. 50 mg is the norm for children 6-11 years of age per day, divided into 3 doses.

And now about how to take Trimedat before or after meals. If you drink the agreed remedy 15-30 minutes before meals, then this will be the best option for both adults and younger generations. If for some reason it is not possible to do this, then you need to take them systematically after meals, 20 minutes later, throughout the course of treatment.

The drug Trimedat is available only in tablet form

At the same time, if symptoms of dyspepsia occur in the form of pain, spasms or colic, you should not rely on the fact that Trimedat should be taken before or after meals. The duration of therapy, at the above dosages, depends on the disease and physical condition of the patient. And this should be determined by the attending physician.

Cost of the drug

For the drug Trimedat, the price is not specified in the instructions for use. Retail offers on the pharmaceutical market indicate that prices for domestic and imported drugs are practically the same. You can easily find pharmacies that charge from 140 to 200 rubles for a medicine with a dosage of 100 mg for 10 tablets in a blister.

A product with a higher dosage and 30 tablets in a blister will cost approximately 300-400 rubles. Having studied the instructions for use for the drug Trimedat at the price of the drug, you can find out what products can replace it.

Trimedat - official instructions for use (tablets)


Drugs with similar effects

The entire set of analogues for the drug Trimedat can be divided into 2 main groups - these are, in fact, analogues and synonyms. A trimedate analogue may have one that contains an identical active principle. Such a structural analogue is called a synonym. The Trimedat analogue may also be of a different type. For example, the similarity of analogue drugs in terms of therapeutic effect. That is, the effect of these drugs is approximately the same, but the active substances are different. Among all the substitutes for Trimedat are:

  • Debridat (synonym);
  • Neobutin (synonym);
  • Tributate (synonym);
  • Trimpa 200 (synonym);
  • Dicetel; Trigan;
  • Kolofort; Sparex;
  • Spasmomen.

The names of many more non-structural analogues can be given. For the drug Trimedat, analogues are cheaper, with a significant difference in price, and are rare. As an example, we can cite Indian Trigan ampoules, which are approximately half the price. However, if you recalculate the amount of active ingredient, the liquid version will be more expensive. In comparison with the drug Trimedat, the price of the cheap analogues is not much different from the original.

Reviews at a Glance

Information that every potential buyer of any medicine, including Trimedat, is interested in: instructions for use, reviews, price. Among the responses about this medicine, the positivity is, if not 100%, then a figure exceeding 90%.

A lot of positive reviews of this remedy are associated with its use for the treatment of chronic gastrointestinal diseases. Particularly noteworthy are the responses of women who took the medicine after abdominal surgery.

Many parents send emotional positive responses to the described remedy, due to its “saving” symptomatic effect in the suffering of their children. Single negative reviews are associated with a discrepancy between the expected effect and the one actually obtained, as well as in cases where the drug had to be abandoned due to a side effect.

Detailed information about the drug Trimedat: instructions for use, price, reviews, analogues - all this data serves informative purposes. To actually use the medication, you must consult a doctor and act exclusively within the framework of his instructions.

Video: Symptoms and treatment of irritable bowel syndrome (E. Malysheva)

Trimedat is a popular medicine in the field of gastroenterology. The main active ingredient is trimebutine. The remaining components help the absorption of trimebutine and ensure its delivery to the intestines. Trimebutine maleate has an antispasmodic effect, so it is often used for pancreatitis to relieve symptoms.

Trimedat exhibits maximum activity 30 to 90 minutes after administration. During this period, it is absorbed in the gastrointestinal tract and penetrates the blood. After providing a therapeutic effect, most of the substance is administered with urine on the first day. Since this medicine does not have toxic properties or a tendency to accumulate, it can be used for long-term treatment.

Features of the action

Trimedat belongs to the category of antispasmodic drugs. It has a gentle effect on the intestinal contraction system.

Trimebutine has the properties of a targeted effect on the smooth muscles of internal organs. Thanks to this, it has the following effect:

  • stimulates muscle contraction in hypokinetic disorders;
  • relieves spasms in hyperkinetic manifestations of diseases, for example, pancreatitis;
  • eliminates colic and bloating;
  • restores intestinal motility and eliminates constipation;
  • restores normal functioning of the sphincter of Oddi;
  • improves the flow of bile and digestive enzymes;
  • promotes the manifestation of the correct intestinal response to undigested food;
  • promotes the timely movement of food from the stomach to the intestines.

Thanks to Trimedat, it is possible to normalize the digestive process and restore the correct chain of reactions of the gastrointestinal tract to incoming food. Unpleasant sensations, heaviness in the stomach, cramps are eliminated. In case of problems with the gallbladder and pancreas, it is possible to restore the full flow of digestive juices and enzymes into the gastrointestinal tract.

When taking the drug, it has a special effect on the intestines, as it is possible to normalize its motility.

Thanks to the targeted effect of the active substance, problems of both directions are eliminated: both hyperkinetic and hypokinetic.

Indications for use

The main prerequisite for prescribing drugs with trimebutine is disruption of the gastrointestinal tract associated with functional disorders.

  • irritable bowel syndrome;
  • diarrhea or constipation;
  • nausea and vomiting;
  • dyspepsia;
  • reflux esophagitis;
  • spasms and pain syndrome;
  • disturbance of intestinal motility;
  • postoperative intestinal obstruction;
  • stagnation of food in the stomach;
  • bloating and flatulence;
  • stagnation of bile and pancreatic secretions.

It is precisely because of the drug’s ability to stimulate the digestive process, eliminate heaviness in the stomach and nausea, and normalize intestinal function that it is often prescribed for pancreatitis.

Additionally, it is worth highlighting the beneficial properties of the drug associated with the preparation of the human gastrointestinal tract for diagnostic procedures.

Contraindications and restrictions

Like other medications, this drug has contraindications. Trimedat is not recommended for use in the following cases:

  1. intolerance to the components of the product;
  2. pregnancy in the first trimester;
  3. breastfeeding period;
  4. individual contraindications.

The drug contains lactose, so it is not suitable for people with lactase deficiency. You also need to pay attention to other excipients, as they can cause allergies.

Sensitivity to this medicine may manifest itself in the form of redness of the skin and rashes on the body, itching. Patients with chronic urticaria are especially prone to this reaction.

Trimedat should be used with extreme caution during exacerbation of pancreatitis.

In case of severe attacks, it is better to stop taking the medicine for a while. In any case, treatment should be supervised by a qualified physician.

As for the pregnancy period, in some cases it is allowed to use Trimedat in short courses. It does not have a toxic effect on the fetus, but is able to penetrate the placental barrier, and due to the lack of information on the effect on the development of the child, it is better not to use the drug unless absolutely necessary.

For the treatment of children, it is allowed to use products with trimebutine, but before reaching the age of three, tablets are prohibited; other forms of medication must be used. If there is no effect or suspicious symptoms appear, use of the drug is discontinued.

Dosage and rules of administration

Trimedat is available in the form of tablets with different dosages of the active substance. They should be taken in combination with other medications to provide a comprehensive effect on the problem, especially with pancreatitis. The exact program and dosage is determined by the doctor.

In general, the following standards have been adopted for maximum daily doses:

  • 75 mg for children 3 - 5 years old;
  • 150 mg for children 6 - 12 years old;
  • 300 - 600 mg for adults and children over 12 years of age.

It is extremely undesirable to allow an overdose, but there are no special instructions in the instructions on this matter.

Trimedat should be taken 3 times a day before meals. The tablets are not chewed and washed down with water. They begin to act after half an hour. For irritable bowel syndrome, the maximum dosage is 600 mg.

To maintain normal functioning of the gastrointestinal tract after completing the main course of treatment, maintenance therapy may be prescribed. Its essence is to take half the dose for 4 to 12 weeks, depending on the recommendations of the attending physician and the diagnosis.

Side effects

In most cases, no side effects are observed after taking the drug. It is safe and non-aggressive in its effects on the body.

However, in exceptional cases, Trimedat may provoke the following abnormalities:

  1. allergic reactions;
  2. temporary hearing impairment;
  3. mental disorders in the form of causeless anxiety;
  4. nausea and diarrhea due to intolerance to components, such as lactose;
  5. menstrual irregularities;
  6. tachycardia.

Such manifestations disappear very quickly after stopping the drug.

Side effects can be reduced by reducing the dosage. In this case, it is possible to continue treatment with Trimedat. If there is a deterioration in the patient's condition, the use of the medicine is completely excluded.

Analogues and compatibility with drugs

Trimedat can be used in combination with almost any drug. It does not detect any specific manifestations of interaction. This property allows this medicine to be used for the complex treatment of most diseases associated with disruption of the digestive system.

For pancreatitis, as well as other gastrointestinal problems, the use of Trimedat analogues is allowed.

These drugs also use trimebutine, but the concentration per unit of drug may differ and different auxiliary components may be present.

Analogues of Trimedat:

  • Trimebutine;
  • Trimebutine maleate;
  • Trimedat Valens;
  • Neobutin;
  • Debridat;
  • Tribudat.

Trimebutine is also available in powder form for the preparation of suspensions and solution for injection. The peculiarity of such forms of drugs containing trimebutine is that it must be administered intravenously in small doses over several minutes. In such cases, it is advisable to use infusion therapy. Suspensions can be used to treat children from the age of 6 months.

In general, this medicine is an excellent assistant in solving problems with the gastrointestinal tract. In case of inadequate functioning of the pancreas and adjacent organs, with the help of Trimedat it is possible to normalize the digestive process and speed up the patient’s recovery. In addition, this drug perfectly eliminates the symptoms of pancreatitis, causes virtually no side effects and interacts well with other medications.

To find out whether Trimedat helps with belching, flatulence and other dyspeptic symptoms, watch the video:

peptic.ru

Reputation: 0

I’m very surprised that everyone is comparing duspatalin and trimedat. In fact, these drugs really belong to the group of antispasmodics. But their purpose must be considered in each specific case. I hope my information will also be useful to someone.

My diagnosis is biliary pancreatitis (hyperkinetic type) - so that everyone understands - bile is produced in an enhanced mode. The pain is localized on the right. This is where it started for me. First it led to gastrointestinal upset, then Reflux. Then - erosion in the stomach and duodenum. Then - severe intoxication, toxicosis, disorder of the cardiovascular, respiratory, and nervous systems.
I came to experienced doctors when I no longer understood what kind of world I was in (

The first thing that was prescribed for the period before hospitalization, in order to hold on - INSTEAD OF NO-SHPA (drotaverine hydrochloride) - DUSPATALIN (mebeverine hydrochloride) as a drug of a similar, but better and PROLONGED ACTION FOR RELIEFING SPASMS.

After hospitalization and test results, he was prescribed trimedat AS A REGULATOR OF MOTOR FUNCTION OF THE GASTROINTESTINAL TRACT My roommate checked with the doctor about the fact that she had been taking Trimedat for 10 days before hospitalization and stopped as prescribed by the doctor at her place of residence. to which the answer was received - Trimedat is a very good drug, but its effect begins to appear at the end of the 2nd week of use, and if you start taking this drug, you need to drink it for AT LEAST 2 months (sometimes 3).
All patients in our ward in the department of chronic diseases of the intestines and pancreas were prescribed trimedate in exactly this course.

Plus enzymes, plus Omez, etc., plus (MANDATORY!) antidepressants (they said that without these drugs it is useless to treat gastrointestinal diseases) - but each had their own option. Plus a diet (I had 5P).

After discharge from the clinic, I took Trimedat for another 2 months.

"The effectiveness of the opiate receptor agonist trimedate in the treatment of disorders of motor function of the biliary tract"
E.P. Yakovenko, N.A. Agafonova, A.V. Yakovenko, A.S. Pryanishnikova, A.N. Ivanov, E.Yu. Lopatina, L.I. Gubaidulina, N.I. Ovchinnikova, Yu.V. Grigorieva, A.V. Kagramanova, I.V. Davletshina.

“...The leading pathogenetic mechanism for the development of biliary-type pain syndrome in functional disorders of the gallbladder and musculoskeletal system is an increase in pressure in the biliary system as a result of a violation of the outflow of bile into the duodenum, caused by a discoordination between the contractions of the gallbladder and the tone of the sphincters of the biliary system. The main goal of treating patients with primary and secondary dysfunctional disorders of the biliary tract consists of normalizing sphincter tone and motor activity of the gallbladder, restoring the normal flow of bile and pancreatic secretion through the biliary and pancreatic ducts. To relieve pain and dyspeptic disorders, medications that normalize the motor function of the biliary system are traditionally used: antispasmodics or cholekinetics. However, a significant proportion of patients have combined and diverse disorders of GB and SO motility. Therefore, the doctor’s arsenal must contain drugs that can restore the motility of the biliary tract, regardless of the type of disorder. Such a drug is the opiate receptor agonist Trimedat (trimebutine), which normalizes both spastic and hypomotor intestinal dyskinesia. However, to date there is practically no data in the literature on the use of trimebutine for motor disorders of the biliary tract. Purpose of the study : to study the effectiveness, safety and tolerability of the drug Trimedat in patients with primary and secondary dysfunctional disorders of the gastrointestinal tract and biliary type. The study assessed the dynamics of pain and dyspeptic disorders caused by impaired motility of the biliary tract; stability of clinical remission achieved after a course of treatment with Trimedat; the effect of the drug on the motor-evacuation function of the gallbladder and the condition of the common bile duct; presence of side effects..."

http://www.trimedat.ru/spec/clin/article_1/

Added (23.03.2013, 15:00)
———————————————
Therefore, now I take Duspatalin to relieve pain and spasms, when the pain on the right is especially sensitive. 2 times a day. I figure out that the second dose should be at night.

And Trimedat is there in case of a “nuclear war”))) and if suddenly... then I’ll take a course for 2 months. minimum.

Added (31.03.2013, 11:52)
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Another clinical study of the drug Trimedat:

“Patophysiology of abdominal pain. Modern approaches to the treatment of motor disorders” Prof., MD. HE. Minushkin, Ph.D. G.A. Elizavetina

Table 1. Areas of distribution and severity of the antispasmodic effect of relaxants

http://www.trimedat.ru/files...._12.pdf

Auxiliary components of Duspatalin capsules Auxiliary components of Duspatalin tablets
Magnesium stearate Lactose monohydrate
Methyl methacrylate copolymer Potato starch
Ethyl acrylate copolymer Povidone K25
Talc Talc
Hypromellose Magnesium stearate
Triacetin Sucrose
Gelatin Gelatin
Titanium dioxide Acacia gum
Shellac Carnauba wax
Iron oxide black
Soy lecithin
Defoamer

Action and therapeutic effects

Based on the type of action it produces, Duspatalin belongs to the group of myotropic antispasmodic drugs. Myotropy means affinity for intestinal smooth muscle. The antispasmodic effect is to relax the smooth muscle and eliminate pain and spasm associated with severe tension.

Duspatalin acts directly on the smooth muscles of the intestine, relaxing it. Since most of the smooth muscle cells are located in the large intestine, the effect of Duspatalin is most pronounced in this section of the digestive tract. A decrease in the tone of smooth muscles of the gastrointestinal tract occurs without affecting normal peristaltic activity. This means that the process of digestion and movement of the food bolus through the intestines is not slowed down or disrupted. That is, the drug selectively acts exclusively on smooth muscles, relieving spasm and associated pain. Duspatalin also very effectively relaxes the systemic system, which is necessary to improve the flow of bile and eliminate the pain syndrome associated with biliary colic.

The advantage and peculiarity of the action of Duspatalin is that the drug eliminates only increased motility, without completely suppressing peristaltic movements. It is thanks to this action that normal intestinal motility is maintained after eliminating excess smooth muscle activity. The drug does not cause reflex intestinal hypotension (severe decrease in tone).

After Duspatalin enters the intestines, the drug is absorbed into the blood and enters the liver, where it breaks down into metabolites during biochemical transformations. The drug is excreted from the body in the form of metabolites, mainly in the urine. Retard capsules are capable of releasing the active substance slowly, and therefore provide a duration of action of up to 16 hours after a single dose.

Indications for use

Since the action of Duspatalin is to eliminate spasms and associated pain in the gastrointestinal tract, the indications for its use are the following conditions:

  • Spasmodic pain in the abdominal area.
  • Intestinal colic.
  • Irritable bowel syndrome (to eliminate various intestinal disorders and discomfort in the abdomen in the area where the intestines are located).
  • Biliary colic.
  • Gallbladder dysfunction.
  • Conditions after removal of the gallbladder.
  • Any secondary spasms of the gastrointestinal tract that are caused by diseases of other organs and systems (for example, cholecystitis or pancreatitis).
  • Functional disorders of the digestive system, which are accompanied by severe abdominal pain (for children over 12 years of age).
  • As a symptomatic remedy to eliminate pain, spasms and discomfort in the intestines.

Duspatalin - instructions for use

Due to the different duration of action, as well as the nuances of using Duspatalin tablets and capsules, we will consider the instructions for use of each dosage form separately.

Pills

The tablets should be taken half an hour before meals. The tablet must be swallowed whole, without chewing or biting it, and washed down with a sufficient amount of clean drinking water (at least half a glass).

Take 1 tablet three times a day before breakfast, lunch and dinner, respectively. The duration of the course of use is determined by the development of a good clinical effect. That is, the pills can be taken until the spasmodic pain stops tormenting the person. After achieving the desired clinical result, the drug should be gradually discontinued over 3 to 4 weeks. This is usually done as follows:

  • 1st week- before breakfast and lunch, take one whole tablet of Duspatalin, and before dinner - half.
  • 2nd week- take Duspatalin twice a day, one whole tablet - before breakfast and dinner, that is, in the morning and in the evening.
  • 3rd week- take Duspatalin in the morning before breakfast, one whole tablet, and in the evening before dinner - half.
  • 4th week– take one tablet per day in the morning before breakfast.

The above scheme for gradual drug withdrawal represents unified recommendations developed by leading Russian clinics specializing in the therapeutic treatment of diseases of the digestive tract.

This scheme, depending on the individual characteristics of the human body, can be shortened or lengthened. For example, if a person tolerates the withdrawal of Duspatalin normally, then the dosage can be reduced not by half of the tablet, but by the whole. As a result, the process of drug withdrawal will take not 4 weeks, but only 2. However, if you feel unwell while reducing the dose by one tablet at once, it is necessary to reduce it by half a tablet. Assessing your well-being after reducing the dosage should be carried out within two days.

Practitioners recommend starting to reduce the dosage with half a tablet. Then, if you want to speed up the process of drug withdrawal, after two days you can reduce the daily dosage by one whole tablet, not half. If a person’s health is satisfactory within two days, then the selected drug withdrawal regimen can be continued until the end of the week. If your health is not satisfactory, you will have to return to the initial option of reducing the dosage by half a tablet. Each subsequent week begins in the same way: reducing the dosage by half a tablet - monitoring your well-being for two days - reducing the dose by a whole tablet if you are feeling well, or continuing the regimen if your health is unsatisfactory.

Duspatalin should not be discontinued abruptly, as withdrawal syndrome may develop.

Capsules

Capsules should be taken 20 minutes before meals, swallowing the pill whole, without chewing it or spilling the contents. The capsule should be taken with a sufficient amount of clean drinking water (at least half a glass). Duspatalin is taken 1 capsule twice a day - morning and evening, before breakfast and dinner, respectively.

The duration of the course of use of Duspatalin capsules depends on the rate of normalization of the tone of smooth muscle cells of the digestive tract. That is, the capsules can be taken until the spasms and associated pain and discomfort disappear completely. After achieving a good clinical result, Duspatalin should be gradually discontinued over several weeks. Do not suddenly stop taking capsules, as this may lead to withdrawal symptoms.

So, the gradual withdrawal of Duspatalin capsules is based on a gradual reduction in the dosage of the drug. Specialists from Russian clinics specializing in the treatment of such conditions have developed a unified method for the gradual withdrawal of Duspatalin, which is as follows: for one to two weeks, you should take only one capsule per day in the morning, before breakfast. Then stop using the drug completely. In this case, after using the drug for a week, one capsule per day, you need to take a break for two days and evaluate your well-being. If no painful symptoms of spasms in the gastrointestinal tract have developed, then you can no longer take the drug. If discomfort is noted, then you should take Duspatalin for another week, one capsule per day, and only then finally stop taking the drug.

Overdose

An overdose of Duspatalin is possible when taking a large dosage of the drug simultaneously. An overdose can lead to increased excitability of the central nervous system. In this case, the remaining drug should be removed from the body by gastric lavage and ingestion of activated carbon or other universal sorbent. In cases of severe excitability of the central nervous system, it is necessary to use appropriate symptomatic medications.

Interaction with other drugs

No interactions with other medications have been identified. Therefore, Duspatalin can be combined with other medications.

Since there are cases of dizziness developing under the influence of Duspatalin, it is necessary to refrain from any activities that require a high concentration of attention and speed of psychomotor reactions during treatment with this drug. This includes driving with caution during the treatment period.

Duspatalin for children - how to take

The drug is approved for use in children only from the age of 12. Adolescents over 12 years of age can use Duspatalin to eliminate various spasms and pain in the gastrointestinal tract. In the practice of European doctors, it is customary to prescribe Duspatalin capsules to adolescents to eliminate heaviness, colic and stomach pain that occurs after eating poor-quality food (for example, all kinds of fast food), or against the background of severe anxiety and psycho-emotional stress. After all, teenagers often complain of abdominal cramps caused by anxiety for any reason. Children can also suffer from irritable bowel syndrome due to poor diet. All these discomforts are relieved by taking Duspatalin. Capsules are more suitable for use in adolescents because they can be taken only twice a day and have a long-lasting effect. Dosages of the drug for adolescents over 12 years of age are the same as for adults.

In situations where children experience spastic pain and discomfort in the digestive tract caused by functional disorders (for example, anxiety, eating junk food, drinking carbonated drinks, etc.), doctors recommend taking one capsule of Duspatalin immediately. Then, at the end of the current day, the teenager needs to take another capsule of the drug before dinner. The next day, if there is no spastic pain and discomfort, you do not need to take the drug. If discomfort is present, then you should take two Duspatalin capsules that day - one in the morning, before breakfast, and one in the evening, before dinner. If the drug had to be taken continuously for a week, then it should be discontinued gradually. This means that you should take Duspatalin for a week, one capsule per day - in the morning, before breakfast. And only after this week can you completely stop taking the drug.

Thus, in case of functional disorders of the digestive tract in adolescents, it is necessary to give them Duspatalin occasionally, that is, as needed. Course use of the drug is not practiced.

If a teenager suffers from bile outflow disorders, then Duspatalin should be given in courses. If symptoms of biliary colic occur, you should start taking the drug two capsules per day - one in the morning, before breakfast, and one in the evening, before dinner. The course of treatment lasts as long as it takes to eliminate spastic narrowing of the bile ducts and normalize well-being. In this case, drug withdrawal is carried out gradually, as in adults. This means that after achieving clinical improvement, it is necessary to reduce the dose to one capsule per day, which is best taken in the morning. For 10 days, the teenager should take the drug, one capsule per day, after which it can be completely discontinued.

Use during pregnancy

During pregnancy, women often have to resort to antispasmodics, since the smooth muscles of the uterus are prone to spasms, which can be transmitted to the organs of the digestive system. To eliminate increased uterine tone, No-shpa is usually used, but Duspatalin is better suited for relieving spasms from the gastrointestinal tract. The fact is that Duspatalin selectively acts exclusively on the tone of the smooth muscles of the digestive organs, and does not have any effect on the uterus and blood vessels.

For pregnant women, Duspatalin has another very important effect - the drug perfectly relaxes the sphincter of Oddi, which regulates the release of bile and pancreatic juice into the duodenum. In pregnant women, the sphincter of Oddi is often tense and closed, as a result of which the normal outflow of bile and pancreatic juice does not occur, which disrupts digestion and leads to cramping pain in the abdomen.

Due to these properties, Duspatalin is well suited for the treatment of spastic conditions of the digestive system in pregnant women. During experimental studies, no negative effects on the fetus were identified. However, similar studies have not been conducted on pregnant women for obvious reasons. Therefore, drug manufacturers recommend assessing the ratio of possible risks and expected benefits from using the drug in a pregnant woman. Because of this, you should not use the drug uncontrollably; you should use Duspatalin only as indicated and after consultation with your doctor.

Pregnant women should take Duspatalin exclusively in capsule form; tablets are strictly prohibited for use. However, it cannot be combined with other antispasmodics, such as No-shpa, Drotaverine hydrochloride or Papaverine. The drug should be taken in the usual dosage - two capsules per day: one in the morning, before breakfast, and one in the evening, before dinner. The course of treatment lasts until the condition normalizes and the clinical symptoms associated with spasms of the digestive tract disappear. Duspatalin should also be discontinued gradually. To do this, you need to take the drug one capsule per day (half the dose) for two weeks, preferably in the morning. After 14 days, you can finally discontinue the drug.

The drug is especially indicated for use by women who, even before pregnancy, suffered from sphincter of Oddi dysfunction (SDO). DSO often accompanies chronic pancreatitis or develops after removal of the gallbladder. In addition, Duspatalin can be taken occasionally, one capsule at a time, if gastric or intestinal colic of a functional nature occurs, for example, due to strong emotions, anxiety, eating any food, etc. In this case, the capsules are taken once, only with the development of spastic pain in the digestive tract.

Duspatalin for pancreatitis - how much to take

Acute and chronic pancreatitis is characterized by the development of severe pain and disruption of the outflow of pancreatic juice into the intestine. To relieve pain and relax the sphincter of Oddi (improving the outflow of pancreatic juice) in pancreatitis, various antispasmodic drugs are used, among which Duspatalin is one of the most effective.

With pancreatitis, severe inflammation and increased production of juice and enzymes develop with simultaneous blockage of the excretory ducts. This leads to self-digestion of the pancreas with enzymes produced by the organ itself. For treatment, spasm of the excretory ducts should be eliminated as much as possible and the release of pancreatic juice into the intestine should be facilitated. Facilitation of the secretion of pancreatic juice is carried out by relieving spasm of the sphincter of Oddi under the influence of Duspatalin.

Duspatalin is used for mild exacerbation of chronic pancreatitis, since the drug effectively eliminates spasm of the pancreatic ducts, facilitating the excretion of juice and relieving pain. In this case, take one capsule twice a day - morning and evening. The duration of the course of use depends on the speed of normalization of the person’s condition. Once the symptoms of pancreatitis go away, you can gradually discontinue the drug. In addition, Duspatalin can be taken during the period of remission of chronic pancreatitis in order to prevent exacerbations. The drug is taken 2 capsules per day - one in the morning and one in the evening, for 2 weeks. Then take Duspatalin for another week, one capsule a day, preferably in the morning. After which the drug is completely discontinued.
More about pancreatitis

Duspatalin and alcohol

Alcohol and Duspatalin are incompatible. While taking Duspatalin, alcoholic beverages should be completely excluded from the daily diet. The fact is that alcohol has an irritating effect, increases spasms of blood vessels and excretory ducts of the pancreas, and also increases the tone of the smooth muscles of the intestines. Thus, Duspatalin and alcohol act in completely opposite ways. Therefore, when taking alcoholic beverages during treatment with Duspatalin, the effect of the drug will be significantly reduced or will not develop at all.

Side effects

In general, Duspatalin is well tolerated and rarely causes side effects. According to the results of a special study on eight drugs that are used to treat irritable bowel syndrome, it was found that Duspatalin took first place in the absence of side effects. However, Duspatalin still has a small list of side effects:

  • dizziness;
  • hives;
  • angioedema;
  • swelling of the face;
  • exanthema (a variant of an allergic reaction);
  • hypersensitivity reactions (for example, itching, redness of the skin, etc.);
  • nausea;
  • headache;
  • diarrhea;
  • constipation.

Contraindications

The only contraindication to the use of Duspatalin is the presence of hypersensitivity, allergies or intolerance to the components of the drug.

Pregnant women and nursing mothers should use Duspatalin with caution.

Analogs

Duspatalin has synonymous drugs and analogues on the domestic pharmaceutical market. Synonyms contain mebeverine as an active ingredient, just like Duspatalin. And analogues are medicines that have a similar therapeutic effect, but contain other substances as active ingredients.

The following drugs are synonyms for Duspatalin:

  • Long-acting capsules Niaspam;
  • Sparex extended-release capsules;
  • Mebeverine tablets.

The following drugs are analogues of Duspatalin:

  • Solution for intramuscular injection and Trigan tablets;
  • Trimedat tablets;
  • Homeopathic tablets Spascuprel;
  • Buscopan tablets;
  • Dibazol tablets;
  • Bendazole tablets;
  • Dicetel tablets;
  • No-shpa tablets;
  • Drotaverine hydrochloride tablets;
  • Papaverine tablets.

Duspatalin - analogues are cheaper in price

Directly from the group of Duspatalin analogue drugs, which are used to treat irritable bowel syndrome, cheaper analogues are Sparex, Niaspam and Trigan.

And in the group of antispasmodics, cheaper analogues of Duspatalin are No-shpa, Drotaverine hydrochloride, Dicetel and Papaverine.

Reviews

Reviews about Duspatalin are overwhelmingly positive. This is due to the high effectiveness of the drug, which helps to quickly eliminate both functional disorders of the digestive system and help in the treatment of diseases. Many people who have used the drug note that the capsules quickly relieve stomach and intestinal colic, which often occur after eating poor-quality food, or against the background of strong psycho-emotional stress or anxiety. People also note that Duspatalin perfectly relieves pain in the stomach and intestines after overeating or eating unfamiliar foods that cause severe colic.

A large group of patients suffering from irritable bowel syndrome also respond positively to Duspatalin. Taking the drug eliminated pain, normalized stool and significantly reduced gas formation. Patients who took a serious course of antibiotics, which caused severe cramping and even colicky abdominal pain, also speak positively about the drug. People note that Duspatalin was excellent in eliminating painful colic. Moreover, the effect occurred quite quickly - literally within 15 - 30 minutes, and the effect of the capsules lasted for a long time.

Separately, it is worth noting the positive reviews about Duspatalin from people suffering from pancreatitis and cholecystitis. According to this category of patients, the drug helped relieve spasm from the bile ducts and pancreatic ducts, which contributed to a significant improvement in well-being. Many people note that Duspatalin is able to relieve pain within 2 to 3 days during exacerbation of cholecystitis or pancreatitis. Patients suffering from these pathologies consider this effect of the drug to be effective. People also note the excellent effectiveness of the prophylactic use of Duspatalin for chronic pancreatitis or cholecystitis.

Negative reviews about Duspatalin are rare, and they are associated with the lack of the expected effect. People note that the pain associated with cholecystitis did not go away a few hours after taking the drug. In this case, people were disappointed and gave the drug a negative rating. However, in case of severe cholecystitis, Duspatalin can eliminate the pain syndrome only after 2 to 3 days of use. Therefore, the drug should not be considered completely ineffective.

Some of the negative reviews are related to the use of the drug for off-label indications. For example, quite often in such cases, people indicate that the drug was ineffective for treating gastritis or stomach ulcers. However, Duspatalin is an antispasmodic and is not intended for the treatment of gastritis and ulcers.

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