What does obstetric physiological department mean? Department of obstetric pathology of pregnancy

Magnesium sulfate, better known as magnesia, is often used during pregnancy. This is enough effective drug to prevent miscarriages caused by uterine hypertonicity. It is also able to reduce elevated blood pressure, swelling and reduce thrombosis. But this is far from the entire list of the drug’s capabilities.

Detailed instructions for using the drug

Composition and pharmacological action. The drug consists of one active substance – magnesium salt of sulfuric acid.

Based on the method of application of the drug, it has different impact on the body:

when taking magnesium sulfate powder orally– it has a choleretic and laxative effect;
with intravenous or intramuscular administration of magnesium solution (in ampoules)– antispasmodic, vasodilator, anticonvulsant, diuretic and sedative effect. In addition, the drug is able to reduce high blood pressure, increase uteroplacental blood flow, and relax overly excited muscle tissue uterus.

Intravenous administration of magnesium can achieve an immediate effect. The duration of action of the drug when administered intravenously is 30 minutes.

It must be taken into account that rapid administration of a magnesium solution is unacceptable!

With an intramuscular injection, the drug must be administered slowly.

When administering the drug into a vein using a dropper, magnesium sulfate is first diluted with a solution of sodium chloride or glucose, and only after that the prepared mixture is administered at a rate of 1 ml per minute.

The solution for intravenous or intramuscular administration must be warm, i.e. You must first warm each ampoule in your palms.

When a magnesium solution is administered intramuscularly, the drug begins to act an hour after the injection, and the duration of its action reaches approximately 3–4 hours.

Directions for use and dosage. For intramuscular and intravenous administration, a 20–25% solution of magnesium sulfate is used. Maximum dose– no more than 40 g per day (dry powder).

When taken orally, the maximum dosage is 30 g per day. To achieve a laxative effect, it is permissible to use a magnesium solution:

1) orally (dilute 10-30 g of powder in half a glass of water to form a suspension, and drink it on an empty stomach or before bedtime);

2) in the form of enemas (dissolving 10 g of dry powder in 500 ml of warm boiled water).

Exceeding the maximum dosage is unacceptable! This can lead to a malfunction of the mother’s brain, as well as cause depression of the respiratory center in the fetus.

Indications and contraindications. Having wide range effects, magnesium is prescribed orally for:

constipation;
cholecystitis, as well as hypotonic biliary dyskinesia.

IV or IM administration of the drug is prescribed for:

ventricular arrhythmia, arterial hypertension;
gestosis, accompanied by convulsions;
threat premature birth;
increased nervous excitability;
magnesium deficiency;
therapy premature detachment placenta;
eclampsia, pre-eclampsia;
epilepsy, encephalopathy;
swelling and urinary retention.

Like any other medicine, magnesia has a number of contraindications:

hypotension, bradycardia, others serious violations heart function;
rectal bleeding and intestinal obstruction;
pronounced renal failure;
respiratory diseases;
prenatal period (you cannot inject the drug 2 or less hours before birth);
hypermagnesemia.

Side effects and overdose. Mostly side effects observed only in the presence of a large amount of magnesium in the blood.

In case of overdose, the following symptoms may appear:

vomiting, nausea;
diarrhea;
flatulence;
confusion;
dizziness and increased fatigue;
thirst and dehydration;
in severe cases, difficulty breathing, cardiac arrest.

In case of overdose of magnesium sulfate, calcium preparations are prescribed as an antidote.

Why is magnesium prescribed during pregnancy?

In most cases, expectant mothers are prescribed magnesium sulfate to reduce increased tone uterus. The drug relaxes smooth muscles, thereby helping to reduce the risk of spontaneous miscarriage (in the 1st and 2nd trimester) and premature birth (in the 3rd trimester). Also, pregnant women with hypertension are prescribed magnesium as injections for blood pressure.

If there is a threat of miscarriage or the possibility of placental abruption, magnesium solution is prescribed even for early stages pregnancy. Treatment is carried out under the supervision of a doctor in a hospital. A week-long course of IVs is usually enough to normalize the tone of the uterus and prevent spontaneous abortion.

On later magnesia is prescribed for the treatment of gestosis. The drug can prevent the development cerebral palsy and also reduce the risk intracranial hemorrhages in the fetus.

What does a pregnant woman need to know about magnesia?

1. Pregnant women should be aware that despite the pain of magnesium solution injections, they benefit the mother herself and her unborn baby.

2. Expectant mothers should not be afraid of flushes of blood to the face and heavy sweating during intravenous drug administration. A slight burning sensation or feeling of heat in a vein is acceptable with this method of administering magnesia, but strong pain– this is already a cause for concern.

3. A pregnant woman should independently check that after administering the magnesium solution, they do not forget to measure her blood pressure in order to avoid its sharp decrease and prevent subsequent fainting.

Mild dizziness and weakness after administration of magnesium should subside within a few minutes. If darkening of the eyes, excessive weakness and nausea occur, you should inform your doctor.

4. Latest Research American scientists say that long-term continuous courses of magnesia during pregnancy are unsafe.

Magnesium is a calcium antagonist, and long-term use magnesium helps to wash out calcium from the bones of the fetus. The course should not last more than 7 days in a row. If necessary, treatment with magnesium is resumed after a break.

5. Also, pregnant women should be informed about the inadmissibility of using magnesia simultaneously with calcium supplements and dietary supplements.

6. Taking magnesium sulfate orally can lead to diarrhea and dehydration, without having any effect on the tone of the uterus and the degree of magnesium deficiency in the blood. Only a dropper of magnesium solution can save a child’s life, so if there is a threat of miscarriage, you should not self-medicate!

In this article you can read the instructions for use of the drug Magnesia. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Magnesia in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications were observed and side effects, perhaps not stated by the manufacturer in the annotation. Analogues of Magnesia, if available structural analogues. Used to treat constipation, reduce high blood pressure, carrying out tubing in adults, children, as well as during pregnancy and breastfeeding.

Magnesia- when taken orally, it has a choleretic effect ( reflex action to mucosal receptors duodenum) and laxative effect (due to poor absorption of the drug in the intestine, a high osmotic pressure, water accumulates in the intestines, the intestinal contents become liquefied, and peristalsis increases). Is an antidote for salt poisoning heavy metals. The onset of the effect is after 0.5-3 hours, duration is 4-6 hours.

At parenteral administration has a hypotensive, sedative and anticonvulsant effect, as well as a diuretic, arteriodilating, antiarrhythmic, vasodilating (on arteries) effect, in high doses- curare-like (depressant effect on neuromuscular transmission), tocolytic, hypnotic and narcotic effects, suppresses respiratory center. Magnesium is a physiological blocker of slow calcium channels and is able to displace it from binding sites. Regulates metabolic processes, interneuronal transmission and muscle excitability, prevents the entry of calcium through the presynaptic membrane, reduces the amount of acetylcholine in the peripheral nervous system and the central nervous system. Relaxes smooth muscles, reduces blood pressure (mostly elevated), increases diuresis.

The mechanism of anticonvulsant action is associated with a decrease in the release of acetylcholine from neuromuscular synapses, while magnesium suppresses neuromuscular transmission and has a direct inhibitory effect on the central nervous system.

The antiarrhythmic effect of magnesium is due to a decrease in the excitability of cardiomyocytes, restoration of ionic balance, stabilization cell membranes, disturbance of sodium current, slow incoming calcium current and one-way potassium current. The cardioprotective effect is due to the expansion coronary arteries, decreased peripheral vascular resistance and platelet aggregation.

The tocolytic effect develops as a result of inhibition contractility myometrium (decreased absorption, binding and distribution of calcium in cells smooth muscle) under the influence of magnesium ion, increased blood flow in the uterus as a result of dilation of its vessels. Magnesium is an antidote for poisoning with heavy metal salts.

Systemic effects develop almost immediately after intravenous and 1 hour after intramuscular administration. Duration of action with intravenous administration is 30 minutes, with intramuscular administration - 3-4 hours.

Compound

Magnesium sulfate + excipients.

Pharmacokinetics

After oral administration, no more than 20% is absorbed dose taken. Penetrates the blood-brain barrier (BBB) and the placental barrier and is excreted from breast milk with a concentration 2 times higher than plasma concentrations. Excreted by the kidneys, the rate of renal excretion is proportional to plasma concentration and glomerular filtration rate.

Indications

For oral administration:

constipation;
cholangitis;
cholecystitis;
dyskinesia of the gallbladder of the hypotonic type (for performing tubages);
duodenal intubation (to obtain a cystic portion of bile);
bowel cleansing before diagnostic procedures.

For parenteral administration:

arterial hypertension (including hypertensive crisis with symptoms of cerebral edema);
threat of premature birth;
convulsions during gestosis;
hypomagnesemia (incl. increased need in magnesium and acute hypomagnesemia - tetany, myocardial dysfunction);
polymorphic ventricular tachycardia(pirouette type);
eclampsia;
encephalopathy;
epileptic syndrome;
urinary retention;
poisoning with salts of heavy metals (mercury, arsenic, tetraethyl lead, barium).

Release forms

Solution for intravenous and intramuscular administration (injections in injection ampoules).

Powder for the preparation of suspension for oral administration in jars of 20 g, 25 g, 40 g, 50 g.

Instructions for use and dosage regimen

Intramuscularly or intravenously. Magnesia is used only as prescribed by a doctor. Doses are adjusted taking into account the therapeutic effect and the concentration of magnesium sulfate in the blood serum.

For hypertensive crises, 5-20 ml of a 25% solution is administered intramuscularly or intravenously. At convulsive syndrome In spastic conditions, the drug is prescribed intramuscularly, 5-20 ml of a 25% solution in combination with anxiolytic agents that have a pronounced central muscle relaxant effect.

At acute poisoning mercury, arsenic, tetraethyl lead are injected intravenously in 5-10 ml of a 5-10% solution of magnesium sulfate.

Side effect

bradycardia;
diplopia;
sudden rush of blood to the face;
headache;
decrease in blood pressure;
nausea, vomiting;
diarrhea;
flatulence;
thirst;
dyspnea;
slurred speech;
weakness;
decreased or loss of deep tendon reflexes;
cardiac conduction disturbance;
heart failure;
hyperhidrosis;
anxiety;
pronounced sedative effect;
polyuria;
uterine atony;
violation electrolyte balance(increased fatigue, asthenia, confusion, arrhythmia, convulsions).

Contraindications

severe chronic renal failure;
hypersensitivity to magnesium sulfate;
appendicitis;
rectal bleeding (including undiagnosed);
intestinal obstruction;
dehydration;
arterial hypotension;
depression of the respiratory center;
severe bradycardia;
AV block;
prenatal period (2 hours before birth).

Use during pregnancy and breastfeeding

During pregnancy, Magnesia is used with caution, only in cases where the expected therapeutic effect exceeds the potential risk to the fetus.

If necessary, use during lactation breast-feeding should be stopped.

special instructions

Take orally or administer parenterally with caution in case of heart block, myocardial damage, chronic renal failure, respiratory diseases, acute inflammatory diseases Gastrointestinal tract, pregnancy.

Magnesia can be used for cupping status epilepticus(as part of complex treatment).

In case of overdose, it causes depression of the central nervous system. Calcium preparations - calcium chloride or calcium gluconate - are used as an antidote for an overdose of magnesium sulfate.

Drug interactions

With parenteral use of Magnesia and simultaneous use peripherally acting muscle relaxants, the effects of peripherally acting muscle relaxants are enhanced.

At simultaneous administration taking antibiotics from the tetracycline group, the effect of tetracyclines may decrease due to a decrease in their absorption from the gastrointestinal tract.

A case of respiratory arrest was described when using gentamicin in infant with an increased concentration of magnesium in the blood plasma during therapy with magnesium sulfate.

When used simultaneously with nifedipine, severe muscle weakness is possible.

Reduces the effectiveness of oral anticoagulants (including coumarin derivatives or indanedione derivatives), cardiac glycosides, phenothiazines (especially chlorpromazine). Reduces the absorption of ciprofloxacin, etidronic acid, weakens the effect of streptomycin and tobramycin.

Calcium preparations - calcium chloride or calcium gluconate - are used as an antidote for an overdose of Magnesia.

Pharmaceutically incompatible (precipitate forms) with calcium preparations, ethanol (alcohol) (in high concentrations), carbonates, bicarbonates and phosphates of alkali metals, salts of arsenic acid, barium, strontium, clindamycin phosphate, hydrocortisone sodium succinate, polymyxin B sulfate, procaine hydrochloride, salicylates and tartrates.

Analogues of the drug Magnesia

Structural analogues according to active substance:

Cormagnesin;
Magnesium sulfate;
Magnesium sulfate Darnitsa;
Magnesium sulfate solution for injection.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.

Magnesium sulfate(Magnesia, magnesium sulfate, Epsom salt, etc.) includes magnesium salt of sulfuric acid. Impurities and excipients this drug does not contain.

The effectiveness of this medicine has long been proven, and the drug is successfully used in various branches of medicine (gynecology, neurology, gastroenterology and many others) due to the numerous effects it has.

Local application of Magnesia for dressings and compresses helps improve blood flow in the skin tissues and achieve an analgesic and absorbable effect.

Sports magnesium is used to dry hands. This ensures a reduction in the slipping of the athlete’s hands when gripping one or another sports equipment or equipment.

Release form

Magnesia is available in various forms:
1. In ampoules of 10 ml - 25% solution (10 pcs. per package).
2. In ampoules of 5 ml - 25% solution (10 pieces per package).
3. Powder for preparing the suspension - in packages of 10, 20 and 25 g.
4. Powder, balls, briquettes of magnesium sulfate for athletes – various shapes release and packaging.

Instructions for use of Magnesia

Indications for use

epilepsy;
eclampsia;
threat of premature birth;
hypomagnesemia (magnesium deficiency in the blood);
ventricular arrhythmias (including with low concentrations of potassium and magnesium in the blood);
excessive nervous excitability (with epilepsy, increased mental and motor activity, convulsions);
increased sweating;
hypotonic dyskinesias biliary tract;
duodenal intubation;
heavy metal poisoning;
constipation;
urinary retention;
treatment of warts;
treatment of wounds and infiltrates.

Contraindications

Arterial hypotension;
atrioventricular block (impaired conduction of impulses from the atria to the ventricles);
severe bradycardia;
depression of the respiratory center;
prenatal period;
severe renal failure;
rectal bleeding;

Side effects

Depression of the heart;
bradycardia;
flushes of blood to the face;
sweating;
oppression of the central nervous system;
state of anxiety;
confusion;
polyuria;
thirst;
spasmodic pain.

Interaction with other drugs

With intravenous or intramuscular administration of a solution of magnesium sulfate simultaneously with some other medicines There may be an increase or decrease in the effect of a particular drug:

when magnesia is combined with peripherally acting muscle relaxants, the effect of muscle relaxants is enhanced;
with Nifedipine - severe muscle weakness may be provoked;
with anticoagulants (oral), cardiac glycosides, phenothiazine - the effectiveness of the drugs decreases;
with Ciprofloxacin – the antibacterial effect increases;
with Tobramycin and Streptomycin - the antibacterial effect is reduced;
with tetracycline antibiotics - the effectiveness of antibiotics decreases and their absorption from gastrointestinal tract.

Magnesia is not compatible with some pharmacological drugs:

calcium;
barium;
strontium;
arsenic salts;
carbonates, phosphates and hydrocarbonates of alkali metals;
procaine hydrochloride;
tartrates;
salicylates;

In case of an overdose of Magnesia, it is recommended to use calcium preparations (Calcium gluconate, Calcium chloride) as an antidote.

Treatment with magnesia

How is Magnesia taken orally?

To use Magnesia internally, a suspension is prepared from powder and warm boiled water. The dosage of magnesium sulfate when taking this drug orally depends on the indications and age of the patient.

If Magnesia is used as cholagogue , it is used as follows:

20-25 g of powder is dissolved in 100 ml of warm boiled water;
Before taking, stir the solution and immediately drink 1 tablespoon of the medicine;
The solution must be taken before meals 3 times a day.

For performing duodenal sounding prepare a solution of 10% or 25% concentration, and introduce the prepared solution into the duodenum through a probe (10% - 10 ml or 25% - 50 ml).

As a laxative:

for adults and children over 14 years of age, a solution is prepared from 10-30 g of magnesium sulfate powder (the powder is diluted in 100 ml of warm boiled water);
the resulting solution is taken at night or in the morning before meals;
To speed up the laxative effect, you can take it additionally a large number of warm boiled water (in this case, loosening of the stool will occur within 1-3 hours).

It is not recommended to use Magnesia solution as a laxative for several days in a row, because This drug irritates the mucous membrane of the gastrointestinal tract.

In some cases, to combat chronic constipation, medicinal enemas with a solution of magnesium sulfate (20-30 g per 100 ml of water) may be prescribed.

Intravenous and intramuscular injection Magnesia
When using Magnesia as an anticonvulsant, antihypertensive, antiarrhythmic agent, the drug is administered intramuscularly or intravenously.

For intramuscular administration, a 25% solution is used, produced in ampoules, which does not require additional dilution. When administering this drug intravenously, the ampoule solution can be administered undiluted, or diluted with a solution of sodium chloride or 5% glucose.

Usually, for intravenous use, Magnesia solution is diluted, since rapid simultaneous administration in undiluted form can provoke a number of complications.

Intramuscular administration of Magnesia is accompanied by painful sensations.

Before giving an injection or drip nurse should warn the patient that if a number of symptoms appear (dizziness, headache, flushing of the face, decreased heartbeat), they must be reported to the doctor immediately. The drip infusion itself may be accompanied by a slight burning sensation along the vein, which gradually stops. At the end of the drip infusion, control measurement pressure and pulse.

Magnesia dosage
When taken orally, the highest single dose Magnesia – 30 g.

The maximum daily dose of Magnesia for intravenous or intramuscular administration is 200 ml of a 20% solution.

Magnesia for children

Quite often, Magnesia is used to treat constipation in children. For these purposes, the powder of the drug is used, which is diluted in 100 ml of warm boiled water. The dosage depends on the age of the child:

6-12 years – 6-10 g per day;
12-15 years – 10 g per day;
over 15 years old – 10-30 g per day.

To determine a more accurate daily dose For magnesium, you can use the following formula: 1 g multiplied by 1 year of the child (for example: a 7-year-old child can be given 7 g of Magnesia powder per day).

For constipation in children, magnesium sulfate can also be used in the form of medicinal enemas. For an enema, you need to prepare a solution of 20-30 g of powder and 100 ml of warm boiled water. The amount of solution for administration into the rectum, depending on the age of the child, is 50-100 ml.

Magnesia is prescribed intravenously or intramuscularly for children only for relief emergency conditions(severe asphyxia or intracranial hypertension). In these cases, intravenous or intramuscular administration of Magnesia is used even for newborns.

Magnesia during pregnancy

Magnesia during pregnancy is most often used to relieve hypertonicity of the uterus (relaxation of its smooth muscles). These measures become necessary in conditions such as threatened miscarriage or premature birth.

In such cases, intravenous or intramuscular administration of Magnesia is used in a hospital setting, under constant monitoring medical personnel. This is explained by the fact that when administered intravenously, this drug enters not only the mother’s blood, but also, passing through the placental barrier, enters the fetal blood. Thus, Magnesia can cause respiratory depression in the fetus and a sharp decline blood pressure. Due to possible development For such complications, stop using Magnesia solution 2 hours before the expected birth.

Due to its diuretic effect, Magnesia can be used during pregnancy to reduce edema (for example, in preeclampsia and eclampsia). In this case, a solution of magnesium sulfate is introduced dropwise, slowly. To avoid complications, the doctor monitors the dynamics of pressure, respiratory rate, concentration of magnesium ions in the blood and tendon reflexes.

Tubazhi with Magnesia

Tubage with Magnesia improves the movement of bile through bile ducts and can be an excellent prevention of cholelithiasis. This procedure can be carried out in conditions medical institution or, as prescribed by a doctor, at home.

Indications for tubing:

bile duct dyskinesia;
stagnation of bile in the gallbladder.

Contraindications:

cholelithiasis;
rectal bleeding;
intestinal obstruction;
dehydration of the body;
tendency to hypotension;
attack of appendicitis;
high levels of magnesium in the blood;
exacerbation of any chronic disease;

Magnesia, available in powder, and boiled water are used for tubage. Tubage with Magnesia is carried out in the morning once a week. It is most effective to carry out this procedure within 15 weeks (unless your doctor prescribes otherwise).

Before the procedure, it is advisable to follow a gentle diet, which should be followed on the day of the procedure. You should avoid spices, smoked, pickled and salty foods. You can include in your diet various cereals(except for millet, pearl barley and semolina) and dishes from boiled or baked vegetables.

Procedure:
1. Stir 1 tablespoon of Magnesia powder in 250 ml of warm boiled water (you can use purified drinking water heated to 40 degrees or alkaline mineral water without gas).
2. Drink the prepared mixture.
3. Lie on your right side.
4. Apply a heating pad or a bottle of water to the liver area. warm water.
5. Lay down for about 1.5 hours.

The effectiveness of the tubing can be determined by color feces. The procedure is considered successful if the first stool excreted has a greenish tint. If there is no stool, constipation should be eliminated and the tubage procedure with Magnesia should be performed again.

After completing the tubage procedure, it is advisable to eat a salad of grated boiled beets, seasoned vegetable oil, or from grated raw carrots and apples.

Magnesia for colon cleansing

Colon cleansing with Magnesia can be carried out not only to eliminate constipation, but also to remove toxins accumulated on the intestinal walls from the body. This technique guarantees bowel cleansing and, when performed correctly, is considered safe.

The procedure can be performed both in hospital and at home in the absence of contraindications to it. To carry it out, a medicinal enema is performed from dry Magnesia powder and warm boiled water. 20-30 g of dry powder are dissolved in 100 ml of warm boiled water. The resulting solution is injected into the intestinal lumen and causes swelling of the feces. Within 1-1.5 hours, toxins accumulated on the intestinal walls are removed from the body along with feces.

Such enemas are performed in one course, and their number is determined by the doctor. IN last years Among doctors there are many opponents of such intestinal cleansing, who point to whole line possible complications. Other experts, on the contrary, advocate the advisability of such cleansing procedures, but recommend carrying them out only after consultation with a doctor.

Magnesia in physiotherapy

Magnesia is used for some physiotherapeutic procedures:

compresses - a 25% solution is used, the compress is applied to the desired area for 6-8 hours, then the skin is washed with warm water and lubricated with a rich cream (since magnesium sulfate has a drying property);
electrophoresis – can be performed using different methods, a 20-25% solution is used to carry it out;
medicinal baths - dry magnesium sulfate powder is used, which is dissolved in water; The water level in the bath should not reach the level of the heart.

Compresses with Magnesia have a warming property and increase blood flow to skin. They can be used to treat infiltrates after injections, diseases of the joints and muscles.

The purpose of electrophoresis with Magnesia is more extensive. Under the influence of electrodes, a solution of magnesium sulfate penetrates into the deep layers of the skin and blood vessels, which helps normalize the psycho-emotional background, blood circulation and muscle condition. The duration of the procedure depends on the indications, health status and age of the patient.

Therapeutic baths with Magnesia are used not only to relieve physical and psycho-emotional stress, but can also be used to provide the following therapeutic effects:

decline blood pressure;
increased blood microcirculation;
elimination of spasms of small bronchi;
prevention of seizures in pregnant women;
increased blood circulation in the genitourinary organs;
muscle relaxation;
strengthening metabolic processes;
recovery after serious illnesses and injuries.

Magnesia for weight loss

Weight loss with the help of Magnesia is becoming quite popular among those who are trying to lose weight. excess weight. For this purpose, it is used internally (as a laxative) and in the form of baths.

According to the recommendations of this weight loss technique, Magnesia should be taken orally to activate digestive processes and regularly loosen stools. The drug is prepared in the same way as to provide a laxative effect.

To prepare baths use a mixture of Magnesia with table salt and salt Dead Sea. Before preparing the solution, approximately 100 liters of water (about 40 o C) are taken into the bath, in which a mixture of salts is dissolved.

Composition of the bath salt mixture:

4 packages of 25 g of Magnesia;
500 g table salt;
500 g Dead Sea salt.

The procedure should take no more than 25 minutes. After taking a bath, it is recommended to dry the skin and apply a moisturizing cream or lotion to it.

Bath renders beneficial influence on the skin and the body as a whole: promotes the elimination excess fluid from subcutaneous fat, normalization of metabolism and psycho-emotional state. In addition, along with sweat from upper layers toxins are removed from the skin.

It is possible to lose weight with the help of such baths, but only if you follow a rational diet and sufficient physical activity.
"Magnesia" is natural, it has high level content of magnesium ions and bicarbonates. That is why it is recommended for use in the treatment of diseases associated with magnesium deficiency in the body. Magnesium mineral water recommended for treatment:
These properties of magnesium sulfate are actively used by athletes, climbers and people in certain professions. In recent years, for ease of use, products have begun to be produced in the form of balls or briquettes, which are made from compressed Magnesia. When crushed, they turn into a powdery state.

Magnesia - known to everyone pharmaceutical drug, which has a wide range of applications and excellent performance indicators. To be able to evaluate the benefits that it can bring this medicine, you must read the instructions for use of the drug magnesia.

Magnesia is used both for the relief of acute pathological conditions, and in complex long-term therapy chronic diseases.

Release form and composition

Magnesia – magnesium sulfate (magnesium salt of sulfuric acid) – chemical compound, which has the appearance of a whitish powder, is found in natural sea water.

Magnesium sulfate is commercially available in two forms: dry form(powder, briquettes) and wet form (injection).

The powder is produced without any auxiliary substances; the solution also contains water for injection, which acts as a solvent for magnesium powder.

The powder is available in 5g and 10g packages. and 25 g., used for oral administration (inside).

The solution has a concentration of 25%, packaged in ampoules with a capacity of 5 ml. and 10ml.

Indications for use

Oral use of magnesia powder is recommended for diseases of the gastrointestinal tract. The drug helps with constipation, causing an influx of fluid through the walls of the small and large intestines, and has choleretic and antispasmodic effects. The detoxifying properties of magnesia are noted - the drug binds the toxic elements of certain metals and salts.

Excretion of magnesium by the kidneys provokes a relative diuretic effect.

Injection use of the drug can reduce blood pressure and prevent the development of convulsive syndrome.

Setting up heartbeat, dilates blood vessels, has a mild sedative effect.

The use of magnesium sulfate is indicated for the following diseases and states:

magnesium deficiency
arterial hypertension, cerebral edema, hypertensive crisis, tachycardia
concussion, brain contusion, age-related or hormonal disorders carrying out nerve impulses in the brain, epilepsy
poisoning with barium compounds, heavy metal salts
constipation, biliary tract disorders, cholecystitis, formation of fecal stones
some dermatological diseases.

Magnesia in the form of powder or granules received wide application V professional sports to cleanse the body and additionally remove toxins.

Mode of application

Injections

The injection form is used as an intravenous or intramuscular injections. Intravenous use the drug allows you to achieve the expected result in 10-20 minutes, the result lasts up to two hours.

Intramuscular administration of magnesium allows you to evaluate the result after 40-60 minutes, the effect lasts about 4 hours.

At hypertensive crisis, in convulsive status, adults are prescribed 5-20 ml of 25% magnesia solution intravenously in a stream, slowly. Patients note a feeling of heat spreading from the injection site throughout the body; the rate of administration should be controlled by the patient’s well-being.

For eclampsia, 10-20 ml of a 25% solution intravenously or intramuscularly.

For convulsions in children, a 20% solution of magnesium is administered, the dosage is calculated according to the principle of 0.1-0.3 ml/kg of the child’s weight, the drug is administered intramuscularly.

Powder

Powder for oral use is diluted with drinking water and accept in certain dosages:

biliary dyskinesia– 20g of the drug + 100ml of water. 1 tablespoon, 3 times a day, 10 minutes before meals
constipation– 20-30g magnesia powder +100ml water. Drink the entire contents at night or on an empty stomach. It is not recommended to repeat the procedure more often than once a month. The same solution is available for use in the form of warm enemas.
poisoning– 20 grams of the drug per 200 ml of water, orally, 1 time per day.

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Side effects

Magnesium sulfate is serious drug, its use is possible only as prescribed by a doctor in strictly prescribed dosages. But even in this case there is a possibility individual reaction for magnesium preparation.

The manifestations of this phenomenon are varied, symptoms can be caused by disruptions in work various systems organs:

From the outside digestive system– nausea, vomiting, diarrhea, bloating, heartburn
From the nervous system – dizziness, fatigue, disturbances of consciousness, headache
From the outside of cardio-vascular system– arrhythmia, bradycardia, anxiety, hot flashes.

Contraindications

Suspicion of bleeding in any part of the gastrointestinal tract makes the use of magnesia powder internally impossible.

Among other gastrointestinal diseases, in which oral administration A drug such as magnesia is contraindicated: intestinal obstruction, foreign body on any part of the gastrointestinal tract, appendicitis, exacerbation of stomach ulcers.

If you are dehydrated, magnesium should not be used internally.

Solution for injection is contraindicated for use in patients with low blood pressure, symptoms respiratory failure. Kidney problems can lead to irreversible consequences, after using the drug.

If there are warning signs of labor or while waiting for the onset labor activity It is not recommended to inject the drug.

The phenomena of hypermagnesemia—an excess of magnesium in the patient’s body—are absolute contraindication to prescribe treatment with magnesium powder or solution.

Overdose

Violation of the dosage of drug administration or incompetent administration of magnesia can lead to an overdose.

The first symptoms pathological increase magnesium concentrations are:

reduction in blood pressure to 90/50mm. rt. Art.;
headache, dizziness;
weakness in the limbs, shortness of breath;
nausea;
diction violations.

If compensatory therapy has not been started, the symptoms of a drug overdose will worsen and add the following signs:

heart rate slows down to 40-50 beats/min
depression, slow reflexes
stopping breathing, heartbeat
pathological acceleration of diuresis.

A patient with these symptoms should be urgently hospitalized in the department intensive care. They're starting active therapy calcium preparations.

Magnesia during pregnancy

The use of the drug is permitted during pregnancy; its use is widely used in two conditions:

threat of miscarriage or premature birth (the drug helps relax the muscles of the uterus, neutralizes tone)
prevention of seizures and lowering blood pressure in eclampsia

Use of the drug in correct dosages does not cause any harm to either the mother or the fetus, but an overdose can be fatal.

Associated effects of using magnesia during pregnancy are an anti-edematous effect and relief from constipation.

Magnesia for papillomas and warts

The vasodilating, resolving effects of magnesium sulfate make the drug effective in the treatment of warts or papillomas.

For external treatment For warts, it is recommended to use compresses made from diluted magnesia powder or electrophoresis with this drug.
Using the powder internally promises to get rid of pathological growths on the skin, but you must remember the accompanying laxative effect.

Recipe:

To prepare a compress, dilute 20 magnesia preparation powder in 0.5 l. water.
Apply the moistened gauze pad to the affected area.
The exposure time of the drug is 10-15 minutes.
It is recommended to repeat the procedure twice a day for 2-3 weeks.

The wart should gradually dry out and fall off.

For electrophoresis with magnesium at dermatological diseases It is recommended to consult a physiotherapist, he will prescribe the necessary diagram treatment.

Storage conditions

Storage temperature 10-25 o.

An open bag of powder is stored no more than 48 hours.

The drugs are stored without damage to the original packaging, subject to climatic standards:

powder – 5 years;
injection solution – 3 years.

Price

In Ukraine, 25g of magnesia powder will cost 6-8 UAH (18-25 rubles), 10 ampoules of 5 ml of 25% solution - 12-15 UAH (36-45 rubles).