Etamzilat: instructions for use and what it is needed for, price, reviews, analogues. Etamsylate solution for intravenous and intramuscular administration of scfc

Etamzilat tablets instructions for use – taken orally, the dose is selected separately for each patient. In most cases it is about 0.5 g, the dose should be divided into several parts.
Etamzilat instructions for use injections

  1. Sodium ethamsylate in injection form is administered intravenously or intramuscularly.
  2. The average dose is 0.01 g/kg body weight.
  3. The drug can be used locally by applying a swab moistened with the solution to the skin lesion.

Etamsylate during pregnancy and heavy periods

During early pregnancy, Etamzilat is not prescribed in injections. Tablets can only be taken if there is no risk of harm to the fetus. In the 2nd and 3rd trimesters it is used:

  1. To eliminate minor bleeding.
  2. When elements of the placenta are detached.
  3. To combat nasal hemorrhages.

For heavy periods, Etamzilat is prescribed 1-2 tablets or 1-2 ampoules 2-3 times a day, for 10-14 days, starting the course 5 days before the end of the cycle. For best effect, it must be repeated during the next menstruation.

Etamsylate dosage

  1. 180 minutes before surgery, preventively prescribe up to 750 mg orally or administer 2 ampoules. Within 24 hours after surgery, up to 6 tablets or 2 ampoules of the drug are prescribed to prevent iatrogenic hemorrhages.
  2. For pathologies of the blood system, 1500 mg per day is prescribed orally, every other day for 2 weeks.
  3. Etamsylate for menstruation and dysfunctional uterine bleeding is prescribed orally at a dose of 500 mg for 10 days, then the dose is reduced to 250 mg per day during an exacerbation.
  4. For retinal pathology caused by diabetes mellitus, 250–500 mg of the drug is taken orally for 2 weeks.

Composition and release form

  1. Powder.
  2. Solution for injection 125 mg/ml, ampoules of 2 ml, 10 ampoules per package.
  3. Etamsylate tablets 0.25 g, 10 and 50 pieces per package.
  4. Tablets 0.05 g for children.

Etamzilat – price and packaging

  1. The price of Etamzilat in tablets 0.25 g, 50 pieces per package, is 45 UAH / 120 RUR.
  2. The price of Etamzilat in ampoules of 2 ml of 12.5% ​​solution, 10 pieces per package on average is 25 UAH / 67 RUR.

Vitamin K preparations

Pharmacological properties

Etamsylate is a powerful hemostatic agent, improving the contact between the endothelium and platelets. It reduces capillary permeability and the synthesis of substances that destroy blood clots and dilate blood vessels. As a result, platelets adhere better to the vascular wall at the site of disruption, significantly reducing blood loss.

Digestibility

Etamsylate is completely absorbed in the small intestine when administered orally. Through the mucous membrane it enters the blood, where it is almost completely bound to blood plasma proteins. The maximum concentration of the drug is achieved after 2.5-3 hours.

When administered parenterally, the therapeutic effect occurs within 10-30 minutes. The maximum concentration of the drug in the blood is achieved after 1 hour. Unchanged Etamzilat is excreted in the urine by 75% within 24 hours.

Overdose

There is no information about overdoses.

Etamsylate indications for use

Etamsylate is used in the following cases:

  • Hemostasis and prevention of hemorrhages during surgical interventions in gynecology, urology, ENT, ophthalmology, dentistry.
  • Dysfunctional uterine bleeding.
  • Vascular pathologies associated with diabetes types I and II.
  • Bleeding from the respiratory and digestive systems.
  • Hereditarily caused increased bleeding.

Etamsylate contraindications

Taking Etamzilat is contraindicated in the following cases:

  • Hypersensitivity to the components of the drug.
  • History of thrombosis and thromboembolism.
  • Taking combined oral contraceptives.
  • Acute intermittent porphyria.
  • Tumor diseases of hematopoietic and lymphatic tissues.

Etamsylate side effects

Nervous system:

  • Vertigo.
  • Headache.
  • Loss of sensation in the legs.

The cardiovascular system:

  • Facial redness.
  • Hypotension.

Gastrointestinal tract:

  • Burning sensation in the esophagus.
  • Heaviness in the stomach.

The immune system:

  • Hypersensitivity reactions.
  • Decrease in the population of B-lymphocytes.

special instructions

  1. With caution: patients with transient attacks of hypotension or hypertension.
  2. Etamsylate is not prescribed as monotherapy for thrombocytopenia.
  3. If the injection solution turns red, it is not allowed to be used.
  4. If the therapeutic effect does not occur within two weeks, you should consult a doctor.

Drug interactions

  1. It is prohibited to administer in the same syringe with other medicinal substances.
  2. Simultaneous use with dextrans reduces the therapeutic effect of the latter.
  3. Aminocaproic acid enhances the hemostatic effect.

Terms of sale

Dispensed by prescription.

Storage conditions and shelf life

Shelf life: 3 years. Store at a temperature of 15-25 °C, out of the reach of children. Avoid direct sunlight.

Etamzilat reviews

The drug has established itself as an effective hemostatic agent. The vast majority of women who use Etamzilat for heavy menstruation and dysfunctional uterine bleeding note a positive therapeutic effect.

The most common side effects are dizziness and transient hypotension. Some patients experience an allergic reaction in the form of a skin rash. Doctors also speak positively about Etamzilate and actively use it in surgery and therapy to prevent and stop bleeding.

The volume of menstrual flow not only depends on the health of the reproductive system, but also affects self-feeling. If it is too large, poor health is inevitable, as large blood loss, hemoglobin deficiency and insufficient oxygen supply to tissues occur. Etamsylate is prescribed during menstruation to avoid all this.

Read in this article

Nuances of the effect of the drug

Etamsylate comes in tablets or solution. The name of the drug was given by the active substance; in addition to it, it also contains auxiliary ingredients.

A distinctive feature of the drug is its careful effect on the composition of the blood. It stimulates the production and adhesion of platelets, but in such a way that they do not form into clots that can plug the lumen of the vessel. Etamzilat is prescribed during menstruation because it is capable of:

  • Increase the strength of capillary membranes;
  • Do not interfere with vascular conduction;
  • Increase the speed of platelet connection, increase blood viscosity;
  • Strengthen the coagulability of biological fluid.

Etamsylate stimulates the formation of blood cells in the bone marrow, which contribute to its thickening, as well as their adhesion to the vascular walls. This allows you to stop the excessively active excretion of biological fluid.

Advantages of ethamsylate

The great advantage of the drug, despite its mild effect, is the speed of onset of the therapeutic effect. It is detected already 20-30 minutes after the drug tablets are introduced into the body and continues for another 7-8 hours.

If this is a solution for intravenous or intramuscular injection, etamsylate will begin to act within 5-10 minutes, and its maximum concentration in tissues occurs an hour or two after the injection.

No inconvenience or unpleasant sensations are noticed when using the drug, since its distribution in the cells is even, and it does not provoke vasoconstriction. All of the above makes etamzilat irreplaceable. There are other indications for its use on menstrual days.

Safe use

Heavy menstruation, especially uterine bleeding, does not occur on its own. They are a symptom of a gynecological disease or injury. Therefore, treatment for intense menstruation should be professional, taking into account the cause that caused it.

It is also possible to use the product independently to reduce the intensity of discharge, but in principle it is intended for complex treatment of the disorders that cause it: hormonal problems.

How to take etamsylate during heavy periods, you should ask your doctor, based on specific circumstances:

  • If the discharge is higher than normal, but not very intense, 1-2 tablets are recommended for one-time use. There are 3-4 doses per day;
  • If there is a very large amount of menstrual blood, 3 tablets are prescribed at the same frequency;
  • Severe bleeding may require intravenous or intramuscular injection. For one-time use, 125-250 mg of the drug is enough; it is injected into a vein or muscle 3-4 times a day.

In all cases when etamsylate tablets are prescribed, the instructions for use during menstruation warn that they should not be taken on an empty stomach; this should be done during or immediately after meals.

Mixing the medicine with antibiotics and anticoagulants is prohibited. This will reduce the effect of all drugs and may cause an inadequate reaction of the body.

With proper use of etamzilate, menstruation will pass with a change for the better and overall well-being. Since there will be no abnormal blood loss, the woman will remain able to work and will not feel severe weakness or daytime sleepiness.

The product is also used to prevent heavy discharge. This effect will be revealed the very next time if you start taking the pills on the 3-4th day of the menstrual period. The strength of blood vessels and normal blood viscosity will remain for a month. This will allow you to survive the next critical days without a large loss of biological fluid and a noticeable deterioration in well-being.

Use of the drug during prolonged menstruation

It is well known that there should be no more than seven critical days in each menstrual period. Otherwise, even with a normal volume of discharge, the woman will face high blood loss and all the negative things that follow. That is, low hemoglobin, loss of strength, lack of appetite, and the risk of acquiring anemia are guaranteed.

Etamsylate is also used with high efficiency to stop menstruation that lasts longer than prescribed by nature. 250 mg of medication taken daily will help cope with prolonged menstruation.

In this case, it is taken from any period, but not longer than 10 days. This should be done under the supervision of a specialist, because the dose of the medication may need to be adjusted downward.

Is it possible to use ethamsylate if you are healthy?

Sometimes you want and need the period of critical days with increased worries about your poor health to end faster. And women are trying their best to find a safe way to shorten it using medications.

Etamsylate can be very effective in this regard. By strengthening the vessels of the uterine mucosa, it prevents blood from leaving them, which will shorten the time of removal of menstrual mucus.

But a single dose will not noticeably affect the balance of hormones, so all the sensations characteristic of critical days can remain, and new ones caused by the influence of the drug will be added to them:

  • Headache;
  • Flatulence, nausea, ;
  • Demotion blood pressure, dizziness;
  • Decreased sensitivity of the limbs.

To stop menstruation, Etamzilat is taken 3-8 tablets per day from the beginning, divided into several doses. All rules of use, as with heavy discharge, remain the same. But even in the absence of contraindications or negative perception of the drug by the body, there is a danger of causing harm to it. Because in this case, the use of the product will interfere with the functioning of the reproductive system and may cause its failure.

Etamsylate should not be used frequently to stop menstruation without any problems.

Can the drug cause a negative reaction?

Experts value etamsylate not only for its effectiveness and speed of action, but also for the extremely low likelihood of side effects. And yet they are possible in the form:

  • Nervous disorders;
  • Numbness of the arms and legs;
  • Gastrointestinal dysfunction (diarrhea);
  • Vasomotor manifestations;
  • Skin itching and rashes.

Before taking etamsylate even after visiting a specialist, the instructions for use during menstruation should be read by the patient. In addition to the rules for using the drug, it also describes contraindications:

  • Thrombosis and thromboembolism;
  • Blood clotting disorder;
  • Intolerance to one of the constituent components.

It is undesirable to eliminate bleeding that develops with etamsylate; there is a risk to the fetus.

If the drug is used to treat a nursing woman, the baby will have to be switched to artificial nutrition for this period. The drug should be used with caution and constant monitoring of blood pressure for hypotension.

Etamsylate is successfully used for menstruation quite long time, he allowed many to avoid hospitalization due to their critical days. But all women who use the drug without permission should take into account that this is only part of symptomatic therapy, which does not solve the main problem of the appearance of heavy discharge. If they bother you regularly, ethamsylate alone is not enough.

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  • Etamzilat tablets are an effective medication used to stop bleeding. The drug is widely used in the treatment of various pathological conditions, is safe for health and has an affordable price. Best stops capillary bleeding.

    Etamsylate.

    ATX

    Composition of Etamzilat tablets

    The name of the active substance became the name of the drug: 250 mg of ethamsylate is present in each tablet. The composition of the medication is supplemented by various binding components - sodium metabisulfite, starch, etc.

    The medicine is packaged in blisters; packages of 10 or 50 tablets are offered for sale.

    pharmachologic effect

    Etamzilate has an antihemorrhagic effect, has the property of improving blood microcirculation and normalizing the condition of the walls of blood vessels.

    The drug does not affect the composition of the blood, but activates platelets. After taking pills or giving injections (and the medicine is also available in the form of an injection solution), the blood becomes more viscous, but this does not lead to an increased risk of developing blood clots.

    Pharmacokinetics

    Etamzilate begins to act quite quickly: if it is administered intravenously, then after 5-15 minutes, when taking tablets - after 20-25 minutes. The therapeutic effect lasts for 4-6 hours.

    The drug is excreted in the urine within 24 hours. Half-life is about 2 hours.

    Why are Etamzilat tablets prescribed?

    It is recommended to take the tablets for bleeding of any origin. The medicine is often used by women with heavy periods to reduce the amount of blood discharge. If menstruation lasts for a long time, then Etamzilat will help stop menstruation.

    The drug is also indicated in other cases:

    • during surgical operations performed in various medical fields - dentistry, gynecology, etc.;
    • with damage to the vascular walls, caused by diabetic angiopathy, hemorrhagic diathesis and other diseases;
    • for injuries;
    • in case of emergency, for example, to stop bleeding in organs.

    Contraindications

    Etamzilat tablets have several contraindications for use:

    • hypersensitivity to any component on the basis of which the medicine is created;
    • thrombosis and thromboembolism;
    • porphyria occurring in acute form.

    The drug is prescribed with caution when taking a large dose of anticoagulants.

    How to take Etamzilat tablets?

    The tablets should be taken strictly as prescribed by the doctor or in accordance with the instructions, which must be included in the package with the medicine.

    Most often, when prescribing treatment, a doctor selects the following dosage:

    1. For moderate menstrual bleeding, the daily dose is from 125 mg to 500 mg. The amount is divided by 3-4 times and taken after the same period of time.
    2. For heavy periods, 750 mg per day is prescribed. This volume is also divided by 3-4 times.
    3. If vascular walls are damaged, 500 mg is prescribed up to 4 times a day.
    4. During surgical treatment and to stop bleeding in emergency cases, the doctor selects the dose individually. In such situations, it is not tablets that are most often used, but an intravenous or intravenous solution. intramuscular injection.

    With the help of Etamzilat you can stop bleeding from an open wound. To do this, use a tampon, which is moistened in a solution of the drug. It is better to use a ready-made medicinal composition from ampoules.

    How many days?

    For heavy periods, tablets are taken for 10 days. You should start taking the medicine 5 days before the start of menstruation. In other cases, the duration of therapy is determined by the doctor. The specialist takes into account various factors: the condition of the patient’s body, the cause of bleeding, its abundance, etc.

    For type 1 diabetes mellitus

    The instructions for the tablets do not contain any special instructions regarding the treatment of patients with diabetes mellitus of any type, so the prescription must be made by a doctor, and the patient must strictly follow the specialist’s recommendations.

    Side effects

    Taking the pills may cause a rise in temperature. Some patients, when they develop a fever, think they have the flu. Side effects are possible from various systems and organs.

    Gastrointestinal tract

    Heaviness in the stomach, heartburn.

    Blood-forming organs

    Neutropenia.

    central nervous system

    Dizziness, headaches, paresthesia of the lower extremities, hypotension.

    From the urinary system

    The instructions do not contain information about side effects from the urinary system.

    Allergies

    Skin rashes, itching and other manifestations of allergies. You should abandon Etamzilate and take an antiallergic drug - Loratadine, Diazolin or something else on the advice of a doctor.

    special instructions

    There are no special measures for taking the medicine. If unwanted reactions occur, they can be easily eliminated: just stop taking the pills. Medicinal substances are completely eliminated from the blood within 3-4 days and will not threaten the patient’s health.

    During pregnancy and lactation

    Etamsylate in tablet form can be prescribed to pregnant women to eliminate the risk of miscarriage. But in the 1st trimester it is not recommended to use the medicine, because can harm the development of the fetus.

    The active ingredient of the medication passes into breast milk, so it is not prescribed to women who are breastfeeding a newborn.

    Overdose

    There are no cases of overdose with tablets.

    Interaction with other drugs

    The drug is pharmaceutically incompatible with other medications.

    Alcohol compatibility

    You should avoid drinking alcohol during therapy.

    Analogues

    The only complete analogue of Etamsylate is Dicinone, produced in the form of tablets for oral administration and solution for injection.

    There are many drugs that have the same pharmacological effect, for example, Vikasol, Ezelin, Aglumin. You can use herbal remedies created on the basis of yarrow, nettle, peppermint, etc. They are available in dosage forms that are convenient to take - tablets, suspension, syrup, etc.

    The drug must be stored in a cool, dark place, out of reach of children.

    Best before date

    Manufacturer

    The drug is produced by several manufacturers:

    • Lugansk Chemical Plant, Ukraine;
    • GNTsLS DP Ukrmedprom, Ukraine;
    • PharmFirma SOTEX, Russia
    • BIOCHIMIC, Russia;
    • BIOSYNTHESIS, Russia.

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    Etamsylate is a drug whose main function is to increase the rate of formation of polymeric carbohydrate-protein complexes with a high carbohydrate content in capillaries and the stability of the vascular system. Etamsylate helps improve the permeability of capillary vessels during reactions that naturally occur in the body when exposed to pathogenic factors that cause disruptions in the normal course of life processes and protective-adaptive reactions, and also normalizes blood circulation and helps stop bleeding. The above properties of the drug are due to the active influence of the protein-lipid complex.

    1 ml of emulsion for injection contains: etamsylate 250 mg

    The package contains 5 or 10 ampoules of 2 ml each.

    Indications for use Etamzilat injections

    • prevention and treatment of bleeding in capillary vessels during complications of diabetes mellitus;
    • surgical treatment methods in the field of otolaryngology, ophthalmology, diseases of the oral cavity, urology and gynecology;
    • unforeseen situations with bleeding in the intestines and pulmonary system;
    • with an increased tendency of the body to bleeding and hemorrhage.

    Instructions for use and dosage

    • intravenously or intramuscularly - 125-250 mg up to 4 times a day;
    • administration bypassing the digestive tract - up to 375 mg;
    • children - 10-15 mg up to 3 times a day in equal doses;
    • in case of external use, a cotton swab is soaked in ethamsylate solution and applied to the wound.

    Contraindications

    • increased susceptibility to ethamsylate;
    • tendency to form blood clots inside blood vessels, which prevent free blood circulation;
    • the presence of acute blockages of blood vessels by blood clots;
    • It is not recommended to use the drug as the only means of therapy if the patient is prone to bleeding and hemorrhage.

    Special instructions for the use of Etamzilat injections

    • It is not recommended to use the drug as the only means of therapy if the patient is prone to bleeding and hemorrhage;
    • the drug should be taken with caution if the patient is prone to the formation of blood clots inside blood vessels or blockage of blood vessels by particles of solids;
    • for hemorrhages in various organs associated with an overdose of blood thinning drugs, agents that regulate metabolic processes should be used. Etamsylate is prescribed only as an adjuvant;
    • It is prohibited to administer the drug in the form of an emulsion with drugs other than the solvent in a single syringe.

    pharmachologic effect

    • characterized by the effect of stopping bleeding, the mechanism of action of which has no clear explanation. There is an assumption that Etamzilat reduces the amount of substances that prevent platelet aggregation. This increases the ability of platelets to adhere to the components of the subendothelium, and then they stick together, forming a thrombus. This is what stops bleeding;
    • promotes the formation in the walls of capillaries of polymeric carbohydrate-protein complexes with a predominant content of the carbohydrate part;
    • increases the ability of capillaries to maintain the integrity of the vascular wall under mechanical stress;
    • increases blood circulation;
    • restores blood clotting parameters.

    At the end of the course of treatment, the effect lasts about a week, gradually weakening.

    • When the emulsion is administered intravenously, the blood fluid preservation system is activated after 15 minutes. The effect of stopping bleeding lasts for about 4-6 hours, and after 24 hours it disappears completely;
    • when the emulsion is administered intramuscularly, activation of the system occurs later.

    Etamsylate is excreted in its original form. 5 minutes after intravenous injection, about 30% of the drug is excreted in urine. After 4 hours, the body eliminates the entire administered dose.

    Side effects

    • a burning sensation and discomfort in the chest;
    • a feeling of heaviness under the costal arches below the sternum;
    • migraine;
    • dizziness;
    • branching of the network of blood vessels on the face;
    • decrease in blood pressure in the arteries at the time of heart contraction;
    • necrosis of the skin surface in the lower extremities, the appearance of “pins and needles” or unnatural, suppressed pain when touched.

    Interaction of Etamzilat injections with other medications

    Overdose

    When used in the indicated doses and methods of administration, Etamzilat does not cause an overdose.

    Use during pregnancy

    If there is an urgent need to use the drug during pregnancy, it may be used in cases where the expected benefit to the woman outweighs the risk of side effects in the fetus.

    No negative effects on the fetus were detected during the period of use of Etamzilat.

    Use in childhood

    Possible according to indications in accordance with the indicated dosage.

    Storage conditions and shelf life

    The above information on the use of the drug is presented for informational purposes only and intended for specialists. For complete official information on the use of the drug and indications for use in the Russian Federation, read the instructions for use contained in the package.
    The portal site is not responsible for the consequences caused by taking the medicine without a doctor’s prescription.
    Do not self-medicate, do not change the dosage regimen prescribed by your doctor!

    Etamsylate is a hemostatic agent. It is prescribed to stop bleeding. It is used quite widely, the drug is used after removal of teeth, tonsils, cataracts, and microsurgical operations on the ears, prostatectomy, etc.

    Description and composition

    Etamsylate in the form of a solution is a colorless, transparent or slightly colored liquid.

    As an active ingredient in 1 ml it contains 125 mg of ethamsylate. In addition, the drug contains sodium disulfite, Trilon B, and water for injection.

    The tablets are white, creamy and pinkish tints are allowed, they are chamfered and scored. As an active substance, 1 tablet contains 250 mg of ethamsylate. In addition to this, they contain the following additional ingredients:

    • E 341;
    • E 572;
    • potato starch;
    • sodium metabisulfite;
    • povidone.

    Pharmacological group

    Etamsylate is used to prevent and stop bleeding. It disrupts the interaction between the endothelium and platelets, increases the adhesiveness of the latter, reduces the permeability of capillary walls and the duration of bleeding, resulting in reduced blood loss.

    After intravenous administration, the hemostatic effect occurs after 5-15 minutes and lasts up to 4-6 hours. The active substance penetrates the placenta and is excreted in breast milk.

    After intravenous administration of the drug, its maximum concentration is reached after 10 minutes. After oral administration, the drug is quickly absorbed from the gastrointestinal tract, the maximum concentration in this case is observed 4 hours after taking the tablets.

    Most of the drug is excreted from the body in the urine during the first 24 hours unchanged. After intravenous administration, the half-life is 2 hours, after oral administration - 8 hours.

    Indications for use

    for adults

    Etamsylate is prescribed for the treatment and prevention of capillary bleeding of various natures, including:

    • with diabetic microangiopathy;
    • during and after surgical treatment of eye, gynecological and urological diseases, as well as in ENT practice, dentistry, plastic surgery;
    • when blood appears in the urine, heavy menstruation, including in women with an intrauterine device, bleeding from the nose and gums;
    • for cerebral hemorrhages in newborns and premature infants.

    for children

    Etamsylate should not be prescribed to children if hemoblastoses are diagnosed: osteosarcoma, lymphatic and myeloid leukemia. In other cases, the drug is prescribed according to indications.

    Etamzilate is contraindicated during pregnancy and breastfeeding. After transferring the baby to an adapted formula, the drug can be prescribed according to indications.

    Contraindications

    Etamsylate should not be prescribed if the patient is found to have:

    • intolerance to the composition of the drug and sodium sulfite;
    • acute porphyria;
    • bleeding caused by taking anticoagulants;
    • bronchial asthma;
    • increased blood clotting;
    • thrombosis and thromboembolism;
    • fibrous formations of the uterus.

    Applications and dosages

    for adults

    The treatment regimen with Etamzilate is selected individually. The optimal daily dosage can vary from 10 to 20 mg per kg of weight, it should be divided into 3-4 times. Usually it is 250-500 mg 3-4 times a day. In exceptional cases, the single dosage can be increased to 750 mg, the frequency of administration is 3-4 times a day.

    For prolonged and heavy monthly bleeding, the drug is prescribed in a daily dosage of 750-1000 mg 5 days before the expected menstruation until the 5th day of the next monthly cycle.

    After surgery, the medication is prescribed in a single dosage of 0.25-0.5 g every 6 hours until the likelihood of bleeding disappears.

    for children

    For children, Etamzilat is prescribed in a daily dosage of 10-15 mg per kg of weight. It should be divided into 3-4 times. In neonatology, the drug is administered intramuscularly and intravenously (slowly), therapy is prescribed within the first 2 hours after birth.

    for pregnant women and during lactation

    After transferring the child to artificial feeding, Etamzilat is prescribed as usual.

    Side effects

    The following adverse events may occur during therapy:

    • sensitivity disorder of the lower extremities (numbness, crawling sensations);
    • headaches, vertigo, rush of blood to the head;
    • thromboembolism, decreased blood pressure;
    • nausea, diarrhea, epigastric pain;
    • bronchospasm;
    • back pain;
    • temperature increase;
    • allergies, which can manifest as angioedema, anaphylaxis, rash;
    • acute porphyria;
    • decreased tissue perfusion (it normalizes on its own after some time).

    All of the above effects are not clearly expressed and passing.

    In children in whom the drug was used to prevent blood loss in acute lymphatic and myeloid leukemia, severe leukopenia was more often detected.

    Interaction with other drugs

    Pharmaceutical solution Etamzilat is not compatible with other medications. Therefore, it is unacceptable to mix the contents of the ampoule with any drugs in the same syringe. When Etamisylate is prescribed before the administration of reopolyglucin, it suppresses the antiaggregation effect of the latter; when used after reopolyglucin, it does not have a hemostatic effect.

    The interaction of Etamzilat tablets with other medications has not been noted.

    special instructions

    Treatment should be carried out with caution if a person has a history of thrombosis and thromboembolism.

    Etamsylate is not effective in patients with a low platelet count. Before starting therapy, it is important to exclude other causes of bleeding.

    The drug can only be used in a medical facility for injections.

    If the patient has a blood clotting disorder, Etamzilat can only be used in combination with medications that eliminate this defect.

    If the color of the injection solution has changed during storage, it should not be administered.

    During the treatment period, you must be careful when driving a car, as the use of the medication can cause dizziness.

    Overdose

    There is no data on drug overdose.

    Storage conditions

    The drug, regardless of its release form, should be stored in a place where it is inaccessible to children, at a temperature not exceeding 25 degrees. The shelf life of tablets and injections is 36 months. Etamsylate is a prescription drug, so self-medication is prohibited.

    Analogues

    Analogs of Etamzilat include the following medications:

    1. is a Swiss drug produced in tablets and injections. Injections can be given into a vein or into a muscle. It differs from Etamzilate in the composition of indifferent components, it has a longer shelf life (5 years) and can be used during pregnancy if the benefit to the woman outweighs the possible threat to the fetus.
    2. refers to hemostatic agents, which is a synthetic analogue of the vitamin. It is produced in injections and tablets and can be used in children from birth and pregnant women according to indications.
    3. Nettle leaves are hemostatic agents of plant origin. In the pharmacy you can find it in bulk and in filter bags, the latter are more convenient to use. It can be used as a hemostatic agent from 12 years of age. Contraindications to its use are individual intolerance, childbearing and breastfeeding.
    4. Shepherd's purse herb has a hemostatic effect. It is recommended for use for heavy menstrual bleeding from the age of 12. Plants can be drunk with caution during lactation. It is prohibited during pregnancy.

    Price

    The cost of Etamzilat averages 111 rubles. Prices range from 24 to 135 rubles.

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