Teturam course of treatment. Teturam - an effective fight against alcoholism

In this article, you can read the instructions for use medicinal product Teturam. Reviews of site visitors - consumers are presented this medicine, as well as the opinions of doctors of specialists on the use of Teturam in their practice. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications were observed and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Teturam if available structural analogues. Use for treatment chronic alcoholism and elimination of cravings for alcohol in adults, children, as well as during pregnancy and lactation.

Teturam- remedy for treatment alcohol addiction. It has an inhibitory effect on the enzyme aldehyde dehydrogenase, which is involved in metabolism ethyl alcohol. This leads to an increase in the concentration of the ethyl alcohol metabolite acetaldehyde, which causes flushing of the face, nausea, vomiting, general malaise, tachycardia, and a decrease in blood pressure, which make it extremely unpleasant to drink alcohol after taking Teturam.

Compound

Disulfiram + excipients.

Pharmacokinetics

After oral administration, there is a rapid, but incomplete (70-90%) absorption of the active substance from the gastrointestinal tract. Due to its high lipid solubility, disulfiram is widely distributed in the body and accumulates in various fat depots. Disulfiram is rapidly metabolized to diethyldithiocarbamate (DDC), which is partially excreted as carbon disulfide in exhaled air and partially metabolized in the liver to methyl-DDC. The latter is converted into an active metabolite - diethylthiocarbamic acid methyl ester (methyl-DTC). With mild or moderate deterioration in liver function, metabolism does not change. On the contrary, with cirrhosis of the liver, an increase in the concentration of metabolites in the blood is observed. Metabolites are excreted mainly in the urine. Part is excreted with exhaled air in the form of carbon disulfide. 20% in the form of unchanged disulfiram is excreted through the intestines. Up to 20% of a dose may remain in the body for 1 week or more. Despite the very low levels, disulfiram-ethanol reactions may occur within 5-9 months after implantation.

Indications

For oral administration:

• prevention of relapse during the treatment of chronic alcoholism.

For implantation:

• treatment of chronic alcoholism
• as a detoxifying agent chronic poisoning nickel.

Release forms

Tablets 100 mg, 150 mg, 200 mg and 250 mg.

Other dosage forms, whether it be drops or capsules, does not exist.

Instructions for use and regimen

When taken orally, the dose is 125-500 mg per day, the treatment regimen is determined individually.

When implanted in the subcutaneous fat using a special technique, 800 mg is administered.

Side effect

• metallic taste in the mouth;
• polyneuritis lower extremities;
• neuropsychiatric disorders;
• memory loss;
• disorientation;
• headache;
• skin rash;

Reactions due to the association of disulfiram-ethanol: collapse, disorders heart rate, angina attacks, myocardial infarction, cerebral edema.

Contraindications

• heavy cordially- vascular diseases;
• heavy liver failure;
• diabetes;
• epilepsy;
• nervously- mental illness;
• concomitant use of phenytoin, isoniazid, metronidazole;
• simultaneous use of drinks containing alcohol or taking medications containing ethanol, as well as their use within 24 hours after taking disulfiram;
• pregnancy;
• lactation;
• hypersensitivity to disulfiram.

Use during pregnancy and lactation

Contraindicated for use during pregnancy and lactation.

Before implantation, pregnancy should be excluded. Against the background of the action of disulfiram, it is necessary to use reliable contraceptives.

Use in children

The drug is contraindicated in children and adolescents under the age of 18 years.

special instructions

Use with caution in patients with kidney failure, liver disease, respiratory systems s.

drug interaction

At simultaneous application with anticoagulants, coumarin derivatives (including warfarin), the anticoagulant effect is enhanced, the risk of bleeding increases.

Disulfiram inhibits liver enzymes, therefore, with the simultaneous use of drugs metabolized in the liver, their metabolism may be impaired.

With the simultaneous use of disulfiram with tricyclic antidepressants, phenothiazine derivatives, MAO inhibitors, there is a risk of developing serious adverse reactions associated with drug interactions.

A case of the development of mania in a patient taking Teturam and buspirone is described.

With simultaneous use, the clearance of desipramine and imipramine from the body decreases.

With simultaneous use with amitriptyline, an increase in therapeutic effect disulfiram, but it is also possible to increase toxic action amitriptyline on the CNS.

With simultaneous use, the concentration in the blood plasma of diazepam and chlordiazepoxide increases, in some cases accompanied by dizziness. Under the influence of diazepam, a decrease in the intensity of the disulfiram-alcohol reaction is possible. A case of increased toxicity of temazepam has been described.

With simultaneous use with isoniazid, cases of the development of dizziness, depression are described; with caffeine - the excretion of caffeine from the body decreases; with metronidazole - develops acute psychosis, confusion; with omeprazole - a case of the development of impaired consciousness and catatonia is described.

With simultaneous use with perphenazine, the development of psychotic symptoms cannot be excluded.

With simultaneous use, Teturam inhibits the metabolism and excretion of rifampicin.

With simultaneous use with phenazone, T1 / 2 of phenazone increases; with phenytoin - the effects of phenytoin are enhanced due to an increase in its concentration in the blood plasma, toxic reactions develop.

With simultaneous use with chlorzoxazone, the concentration of chlorzoxazone in the blood plasma increases; with chlorpromazine - possibly increased arterial hypotension.

Analogues of the drug Teturam

Structural analogues for the active substance:

• Antabuse;
• disulfiram;
• Lidevin;
• Esperal.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.

Indications for use:
By prescribing alcohol against the background of the action of teturam, they develop a negative conditioned reflex the taste and smell of alcoholic beverages and long-term treatment achieve partial or complete intolerance to alcohol.
The use of teturam may be accompanied by pronounced side effects, therefore, it is resorted to as one of the later means.
Before starting treatment with teturam, the patient is subjected to a thorough medical examination. In the absence of contraindications, the patient is explained the meaning of therapy and warned about the dangers of drinking alcohol during the treatment period.

Pharmachologic effect:
Taken orally for the treatment of chronic alcoholism in cases where it is not possible to obtain therapeutic effect other methods of treatment (psychotherapy, vitamin therapy, taking apomorphine, etc.).
The action of the product is based on its ability to specifically influence the metabolism of alcohol in the body. Alcohol undergoes oxidative transformations, passing through the acetaldehyde phase and acetic acid. With the participation of acetaldehyde hydroxidase, acetaldehyde is usually rapidly oxidized.
Teturam, blocking the enzymatic biotransformation of alcohol, leads to an increase in the concentration of acetaldehyde in the blood after alcohol intake. According to modern data, teturam is converted in the body into N, N-diethyldithiocarbamic acid (DEDCA) and other metabolites that block metal ions and sulfhydryl groups of enzymes involved in the detoxification of alcohol. Accumulation of acetaldehyde after taking alcohol under the influence of teturam leads to severe changes in the body (the so-called antabuse effect): redness of the skin, a feeling of heat in the face and upper body, a feeling of tightness in the chest, difficulty breathing, noise in the head, palpitations, a feeling of fear, sometimes chills, etc. Significantly lowered blood pressure.

Teturam method of administration and dose:
Treatment with teturam is carried out under the supervision of a physician. The dose is selected individually. Optimal doses (0.25-0.5 g/day) are generally well tolerated and do not cause complications even with long-term use. Teturam doses below 0.15 g/day. are quickly excreted from the body and do not cause the desired effect - sensitization (increased sensitivity of the body) to alcohol.
Treatment with teturam is usually carried out according to following scheme. The first teturam-alcohol test is carried out after 7-10 days from the start of treatment. After taking 0.5-0.75 g of teturam in the morning, the patient takes 20-30 ml alcoholic drink, more often 40% vodka. Repeat samples in stationary conditions carried out in 1-2 days, on an outpatient basis - in 3-5 days. With a weak reaction, the dose of an alcoholic beverage is increased at the next sample by 10-20 ml. The maximum dose of vodka is 100-120 ml. Teturam-alcohol reactions can occur in mild, moderate and severe form. With a severe reaction lasting 1-1.5 hours (severe headache with a feeling of fullness and pulsation, a sharp difficulty in breathing, a significant decrease in blood pressure, darkening of consciousness, psychomotor agitation / high motor and speech activity /, convulsions) intravenously administered 15-20 ml of 1% aqueous solution methylene blue, under the skin - cordiamine, camphor, intramuscularly - cytiton or lobelia, ephedrine, strychnine; produce oxygen inhalation. Intravenously administered glucose solution ascorbic acid. For pain in the heart, Validol, Corvalol, and, if necessary, nitroglycerin are prescribed. With low blood pressure, metasone or ephedrine is administered. In case of a sharp depression of cardiac activity, 0.25-0.5 ml of a 0.05% solution of strophanthin is administered intravenously in 20 ml of isotonic sodium chloride solution or 5% glucose solution. With convulsions - intramuscularly 10 ml of a 25% solution of magnesium sulfate. At severe nausea and vomiting, 10 ml of a 10% solution of calcium chloride or gluconate is injected intravenously, 0.015 g of belladonna extract is given inside, 0.5 ml of a 0.1% solution of atropine is injected under the skin. In the event of convulsive reactions, chloral hydrate is administered as an enema (15-20 ml of a 6% water-starch solution) or tranquilizers (sedative drugs) are used; at psychomotor agitation injected intramuscularly 1-2 ml of a 2.5% solution of chlorpromazine. The patient must be in horizontal position.

Teturam contraindications:
Relative contraindications are residual effects organic damage brain, age over 60 years, endarteritis (inflammation of the inner lining of the vessel), peptic ulcer stomach and duodenum in the stage of exacerbation traumatic disease, residual effects in the aftermath infection brain and stroke, previously transferred teturam psychoses.
Absolute contraindications to the use of teturam are endocrine diseases(thyrotoxicosis / disease thyroid gland/, diabetes mellitus), pronounced cardiosclerosis (overdevelopment connective tissue in the heart muscle), atherosclerosis cerebral vessels, pre- and post-infarction conditions, aneurysm (expansion and / or bulging) of the aorta, coronary insufficiency(inconsistency of blood flow through the cardiac arteries to the heart's need for oxygen), hypertonic disease II and III stages (persistent rise in blood pressure), severe cerebrovascular diseases, heart and vascular diseases in the stage of decompensation (in case of insufficiency of function), pulmonary tuberculosis with hemoptysis, fresh tuberculous infiltrate (areas of tissue increased density in the focus of tuberculous inflammation), bronchial asthma, severe emphysema (lung disease associated with high content air in them), bleeding stomach ulcers, diseases of the liver and kidneys, diseases hematopoietic organs, mental illness, infectious diseases brain, epilepsy and epileptiform syndromes, polyneuritis (multiple inflammation peripheral nerves), neuritis (inflammation) of the auditory and ophthalmic nerve, glaucoma (increased intraocular pressure), malignant tumors, pregnancy, idiosyncrasy (hereditary high susceptibility) to teturam.

Teturam side effects:
When treating with teturam, especially debt, you may experience various violations activities of cardio-vascular system, peripheral and central nervous system, functions of the gastrointestinal tract, liver. Possible allergic reactions(itching, rash) and exacerbation of past diseases (gastritis / inflammation of the stomach /, peptic ulcer of the stomach and duodenum, peptic ulcer of the stomach and duodenum, thrombophlebitis / inflammation of the vein wall with their blockage / etc.).
In some cases, with long-term use of teturam, acute psychoses can occur that resemble acute alcoholic paranoid (states characterized by delusions of persecution, anxiety, fear, motor agitation), acute alcoholic hallucinosis (delusions, vision, acquiring the character of reality) or alcoholic delirium(delusional states). The transition of a hallucinatory syndrome to a paranoid one, a paranoid one to a schizophrenia-like one, etc. is possible.

Release form:
Tablets of 0.15 and 0.25 g, respectively, in packs of 50 and 30 pcs.

Synonyms:
Antabuse, Disulfiram, Abstinil, Alkofobin, Antetan, Antethyl, Antikol, Aversan, Contrapot, Crotenal, Disetil, Espenal, Exorran, Nokzal, Refuzal, Stoptil, Tetradin.

Storage conditions:
List B. In a dry, dark place.

Attention!
Before using the medication "Teturam" you need to consult a doctor.
The instructions are provided solely for familiarization with " Teturam».

Teturam tablets are available at 0.15 and 0.25 g in packs of 50 or 30 pieces, as well as a powder substance.

pharmachologic effect

Teturam tablets are taken from in cases where it is not possible to achieve a therapeutic effect by other means.

Pharmacodynamics and pharmacokinetics

This tool blocks acetaldehyde dehydrogenase , which affects biotransformation ethanol and also increases the content acetaldehyde – ethanol which provokes some discomfort: redness of the face, vomiting, nausea, malaise, decreased . This leads to the development of a conditioned reflex reaction of disgust for alcohol.

The maximum therapeutic effect is noticeable 12 hours after taking the drug and lasts for 10-14 days.

After using the remedy absorption active substance from the gastrointestinal tract - about 80%. It quickly breaks down and regenerates to dithiocarbamate . The drug is given in the form glucuron-conjugate or or diethylamine and carbon sulfide , some of which is excreted through the lungs.

Indications for use

Take powder and pills for drunkenness. They develop a negative conditioned reflex to alcohol. However, the use of this drug can provoke serious side effects, so it is prescribed only if other drugs do not work.

Before starting therapy, the patient is carefully examined. If there are no contraindications for use, the doctor explains how to take the drug and warns that it is dangerous to drink alcohol during treatment.

This medicine can also be used as detoxification remedy for chronic nickel poisoning.

Contraindications

You can not take the drug with:

• hypersensitivity to its active substance;
• diseases of the cardiovascular system at the stage decompensation and compensation ;
• lungs with hemoptysis;
• chronic obstructive pulmonary disease ;
• erosive lesions mucosa of the gastrointestinal tract;
• from the gastrointestinal tract;
• liver failure ;
• diseases of the nervous system caused by infections;
• Do not lie auditory and optic nerves;
• residual effects after NMK ;
• transferred teturamic psychoses ;
• pronounced emphysema lungs;
• impaired renal function;
• neuropsychiatric diseases;
• advanced age;
• children's age (up to 18 years);
• endarteritis ;

Side effects of Teturama

During drug therapy, violations of the functions of the cardiovascular system, nervous system, liver, gastrointestinal tract are possible, for example:

• metallic taste in the mouth hepatitis ;
• polyneuritis lower extremities, memory impairment, neuropsychiatric disorders,;
• collapse , seizures , brain, heart rhythm disturbances, .

In addition, side effects of Teturam are likely in the form of (, rash), as well as exacerbation of diseases that have occurred in the past: gastritis , and duodenum , etc. When long-term use means are possible in some cases acute psychoses similar to acute alcoholic paranoid , alcoholic delirium , spicy alcoholic hallucinosis . hallucinatory syndrome can go to paranoid , a paranoid - in schizophrenic .

Instructions for use Teturam (Method and dosage)

Before therapy, be sure to warn the patient about the consequences and possible complications. If Teturam tablets are prescribed, the instructions for use indicate that they should be taken orally. Dosage - 150-500 mg 2 times a day. The scheme of reception is individual.

After 7-10 days is carried out teturam alcohol test . After taking 500 mg of medication, take 20-30 ml of vodka. If the reaction is weak, the dosage of alcohol can be increased by 10-20 ml, but you can take no more than 100-120 ml of alcohol in total.

After 1-2 days in conditions hospital and 3-5 days outpatient the test is repeated. It is possible to adjust the doses of alcohol and the drug if necessary. Instructions for use Teturam says that in the future you can take a maintenance dosage of 150-200 mg per day for 1-3 years.

Overdose

In case of an overdose of the drug, it is possible neurological complications , oppression of consciousness up to, cardiovascular collapse . Therapy is symptomatic.

Interaction

It is undesirable to combine the medicine with:

• – possible violations in behavior and coordination;
• Phenytoin - possible significant fast growth content phenytoin in with toxic manifestations;
• 5-nitroimidazole derivatives - may appear delirious disorders , confusion.

If the interaction of these medicines sure, carry out clinical observation and control of drug levels in plasma.

With caution, Teturam is used in conjunction with:

• anticoagulants for oral applications - increases the effect anticoagulants possible risk of bleeding. It is recommended to control the content of active ingredients of drugs, it may be necessary to adjust their dosages;
• benzodiazepines – active substance Teturama can increase sedation benzodiazepines by blocking their oxidative. Dose needs to be adjusted benzodiazepine in accordance with the reactions of the body;
• Theophylline – disulfiram suppresses him metabolism . The dosage must be changed depending on the reactions of the body and the content active substance in plasma;
• tricyclic antidepressants - reactions of intolerance to alcoholic beverages increase.

Terms of sale

Specialist prescription.

Storage conditions

Hold this remedy should be in a dry and dark place.

Best before date

The shelf life of the drug is four years. You cannot use it after this time.

Teturam and alcohol

You can not combine Teturam and alcohol. How are the consequences possible? hot flashes, vomiting, erythema , and other side effects. Avoid alcohol and drugs that contain ethanol .

Price from 128 rubles. Analogue is more expensive by 2 rubles

Instructions for use for Teturam

Registration number:

LS-000545

Trade name of the drug:
Teturam

international generic name drug:
Disulfiram

Chemical rational name:
Tetraethylthiuram disulfide

Dosage form:

Tablets

Compound:

1 tablet contains:
Active ingredient: disulfiram - 150 mg
Auxiliary substances: potato starch, colloidal silicon dioxide (aerosil), stearic acid to obtain a tablet weighing 180 mg.

Description
Round, flat-cylindrical tablets of white or white color with a slightly yellowish-greenish tint, with a chamfer.

Pharmacotherapeutic group:

Drug for the treatment of alcoholism

ATC Code: V03AA01

Pharmachologic effect:
Pharmacodynamics:
The action of the drug is based on the blockade of acetaldehyde dehydrogenase, which is involved in the metabolism of ethyl alcohol. This leads to an increase in the concentration of the ethyl alcohol metabolite - acetaldehyde, which causes negative sensations (flushing to the face, nausea, vomiting, tachycardia, lowering blood pressure (BP), etc.), which make it extremely unpleasant to drink alcohol after taking Teturam. This leads to a conditioned reflex aversion to the taste and smell of alcoholic beverages.

Pharmacokinetics
After oral intake absorption of teturam from the gastrointestinal tract (GIT) ranges from 70 to 90%. It is rapidly metabolized, being reduced to dithiocarbamate, which itself is excreted as a glucuron conjugate or converted to diethylamine and carbon sulfide, part of which (4-53%) is excreted through the lungs. The maximum therapeutic effect is achieved 12 hours after oral administration and may continue for 10-14 days after stopping treatment.

Indications:
Treatment and prevention of recurrence of chronic alcoholism. As a detoxification agent for chronic nickel poisoning.

Contraindications:

Hypersensitivity, thyrotoxicosis, diseases of the cardiovascular system in the stage of decompensation (including pronounced cardiosclerosis, cerebral atherosclerosis, pre- and post-infarction conditions, aortic aneurysm, coronary insufficiency, arterial hypertension stage II-III), pulmonary tuberculosis with hemoptysis, bronchial asthma, severe emphysema, erosive lesions gastrointestinal mucosa, peptic ulcer of the stomach and duodenum (in the acute stage), bleeding from the gastrointestinal tract, kidney disease, liver failure, diabetes mellitus, epilepsy, neuropsychiatric diseases, infectious diseases of the central nervous system, polyneuropathy, neuritis of the auditory and ophthalmic nerves, glaucoma, malignant tumors, pregnancy, lactation.
With caution - cardiovascular diseases in the stage of compensation, age over 60 years, peptic ulcer of the stomach and duodenum (in remission), endarteritis, residual effects of the disorder cerebral circulation, psychosis while taking disulfiram in history.

Dosing regimen:
Treatment is given after thorough examination patient and warning about the consequences and complications. The drug is taken orally at 150-500 mg 2 times a day according to an individual scheme. After 7-10 days, a teturam-alcohol test is carried out (20-30 ml of 40% vodka after taking 500 mg of the drug), with a weak reaction, the dose of alcohol is increased by 10-20 ml ( maximum dose vodka 100-120 ml). The test is repeated after 1-2 days in a hospital and after 3-5 days on an outpatient basis with dose adjustment of alcohol and / or drug as needed. In the future, you can use a maintenance dose of 150-200 mg per day for 1-3 years.

Side effects:
Due to the properties of teturam:

• Metallic taste in the mouth.


• Unpleasant odor in patients with colostomy (associated with carbon sulfide).


• Rare cases of hepatitis, sometimes found in patients with nickel eczema who do not suffer from alcoholism.


• Polyneuritis of the lower extremities, optic nerve neuritis.


• Memory loss, confusion, asthenia.


• Headache.


• Skin allergic manifestations.
  Related to teturam-ethyl alcohol combination:
  Cases are described respiratory failure; cardiovascular collapse, arrhythmias, angina pectoris, sometimes myocardial infarction, and neurological disorders; swelling of the brain.
  Complications with long-term use: rarely psychosis, reminiscent of alcohol, hepatitis, gastritis; in persons suffering from cardiovascular diseases, cerebral vascular thrombosis is possible, therefore, if there are complaints of paresthesia in the limbs and face, the drug should be immediately discontinued; exacerbation of polyneuritis.
  When taking doses of alcohol over 50-80 ml of vodka, against the background of taking Teturam, develop severe violations cardiovascular and respiratory systems, edema, convulsions. In this case, detoxification therapy is urgently carried out, analeptics are administered, and symptomatic treatment is carried out. Overdose
  The combination of teturam-ethanol can cause depression of consciousness up to coma, cardiovascular collapse, neurological complications. Treatment is symptomatic.

  Interaction with other drugs
  Contraindicated combinations:



• Alcohol. Intolerance reaction (flushing, erythema, vomiting, tachycardia).
  Avoid taking alcoholic beverages and medicines containing alcohol.
  Unwanted combinations:


• Isoniazid. Violations of behavior and coordination.


• Nitro-5-imidazoles (metronidazole, ordinazole, secnidazole, tinidazole). Delirious disorders, confusion.


• Phenytoin. Significant and rapid rise in plasma phenytoin levels with toxic symptoms(suppression of his metabolism).
  If the combination cannot be avoided, clinical monitoring and monitoring of plasma concentrations of the drug during and after treatment with teturam should be carried out.
  Combinations requiring caution:


• Warfarin (and other oral anticoagulants). Increased effect of oral anticoagulants and risk of bleeding (decreased breakdown of warfarin in the liver). More frequent monitoring of the concentration of warfarin and dose adjustment of anticoagulants within 8 days after discontinuation of teturam is recommended.


• Theophylline. Teturam inhibits theophylline metabolism. As a result of this, the dose of theophylline must be adjusted (reduced dosage), depending on clinical symptoms and plasma drug concentrations.


• Benzodiazepines. Teturam may potentiate the sedative effect of benzodiazepines by inhibiting their oxidative metabolism (especially chlordiazepoxide and diazepam). The dosage of benzodiazepine should be adjusted according to clinical manifestations.


• Tricyclic antidepressants. It is possible to increase the reaction of alcohol intolerance (especially if patients take alcohol while taking teturam).

  Special instructions:

  In the case of simultaneous administration with oral anticoagulants, it is necessary to carry out more frequent monitoring of the content of prothrombin and correction of doses of anticoagulants, which is associated with increased risk bleeding development. Release form
  Tablets of 150 mg. 10 tablets in a blister pack made of PVC film and printed lacquered aluminum foil. 30 or 50 tablets per polymer jar or polymer bottle. Each jar, bottle, 3 or 5 blister packs, together with instructions for use, are placed in a cardboard pack.

  Storage conditions
  List B.
  In a dry, dark place and out of the reach of children at a temperature not exceeding 25°C.

  Best before date
  4 years.
  Do not use the drug after the date indicated on the package.

  Terms of dispensing from pharmacies
  On prescription.

  Manufacturer/organization accepting claims:
  OJSC "AVVA RUS", Russia, 610044
  Kirov, st. Luganskaya, 53A.

23 +

Tough, but effective - helped a lot at the time

Pros: Cheap, efficient

Cons: side effects

Maybe this review will help someone - I had to use it, it was a long time ago, thank God. Teturam is a very cheap drug, there was only enough money for it in those days. First you drink a week - the dose for each is individual, I had 300 mg - 2 tablets, that is. Then in the hospital they gave me a test to find out whether to increase the dose or not. It was during this test that a "demonstration" of what would happen to me if I drink took place. You won’t wish such an enemy - you just start to suffocate, your heart contracts, your breath catches and does not let go. Very dizzy, cold sweat stream - as I remember now. I barely ran to the toilet, where I vomited strongly - so that the insides felt like they were crawling out of my mouth. Then the doctor gave me something, which made it easier. Of course, no one said which drug stopped it, so I realized that if I take the drug on my chest, that's it, the end will come to me. The doctor explained it this way - they say, choose, or hold on, or drink, but it is quite possible that they will bring you to the hospital feet first. That’s why I was never prompted to drink - somehow I didn’t want to die. I took it for two years. There were troubles, the drug was cheap, there were a lot of side effects - I just endured it, I was afraid to get off. The most unpleasant are the eternal urticaria, only from time to time it stops wildly itching, always low blood pressure, headache, frequent insomnia and constant anxiety. But then, when I stopped using it, I realized that it was worth it - when there is not enough willpower to quit once, you need to use drugs, and now Teturam is very effective in this matter.

11 +

Only for those who decide to stop drinking

Benefits: Helps with healing

Disadvantages: only under the supervision of a doctor and if you want to stop drinking

Everyone has long known that an alcoholic, if he does not want to stop drinking, does not see the need for it, will not help. My dad, an alcoholic with 30 years of experience, said: "I drank, I drink and I will drink." When it became completely unbearable, my mother slowly, secretly from my father, began to pour Teturam tablets into his food. Everything became obvious very quickly, dad had a “hard” side effect - tachycardia, nausea. In general, nothing happened. But the sister's husband (the same problem with alcohol) was different. He understood that if he didn’t quit drinking, the family would collapse, so he decided to “quit”. Found the strength, went to the doctor. Teturam really helped in his case. He understood what he was receiving and from what. He also had palpitations. The medicine was taken according to the scheme and only under the supervision of a doctor. As the narcologist said, Teturam is an alternative to coding.

Helped us!

Benefits: Efficiency

Cons: didn't find

I first learned about these pills a year ago. It took to be treated cousin, who, upon the arrival of their army, began to drink heavily, contacted a bad company. Since my brother has a bad heredity, my uncle also abused, we started treatment quickly and "imperceptibly", without his knowledge. Friends complained about Teturam pills. We began to grind them into powder and add them to food, although there are some difficulties here: they cannot be drunk with very hot food and fermented milk products. As for the effect of the pills, I can say that there is an effect almost immediately, 2 days after the "secret" taking of the pills, the brother again gathered with friends, drank a little, but after that, his blood pressure rose, it began strong heartbeat... Most likely, taking such pills cannot but affect health, but no more than alcohol. So, while talking is useless, we are saved by Teturam.

Better not take these pills

Benefits: Only low price

Cons: Lots of cons in the form of side effects

I myself do not suffer from alcoholism, but my mother experienced Teturam on my father. So I share almost personal experience, clearly saw the whole picture of its effect on the body drinking man. On his own, dad would never have agreed to take these pills, so mom, in order not to burden herself with persuasion, decided to secretly put them in his food. At first, everything seemed to be fine, but literally very soon there was a family celebration and dad missed one glass. So the consequences were just terrible, he was shaking, he turned pale, nausea and vomiting began, of course, everyone was not weakly scared, they ate him with various folk ways. After that, my mother didn't do it anymore.

Does your husband or father drink? You don't know what to do with it? Seek help from a narcologist and, perhaps, after talking with a specialist, your sick relative will decide to be coded. And Teturam tablets will be able to help him in this difficult matter. Today we will learn how to take pills, whether they can be purchased without the consent of the doctor, and what consequences if used incorrectly can be. And also find out the opinions of patients and doctors about the effectiveness of this medication.

purpose

The drug "Teturam", the instructions for which are always included in the package, refers to drugs prescribed by doctors for the treatment of alcoholism. international title this remedy - "Disulfiram". The main action of this medicine is the elimination of alcohol dependence. The drug is able to excrete harmful substances from the body and relieve symptoms of intoxication. Often doctors prescribe these pills after a long binge.

How to take the drug "Teturam"?

Tablets must be chewed, cracking them is unacceptable. It is better to take pills before breakfast.

Before therapy, the doctor must inform the patient and inform him about the consequences and possible complications. The drug "Teturam", the instruction to which says that the drug should be taken only under the supervision of a doctor, can be prescribed 150-500 mg twice a day. However, the scheme for taking these pills is individual.

After a week of treatment, the doctor conducts a teturamalcohol test. After taking the drug in the morning, the patient drinks from 20 to 30 ml of a 40% solution of ethyl alcohol or another similar drink. If the reaction turns out to be weak, then the dosage of alcohol can be increased by 10-20 ml, however, so that in the end no more than 100 ml comes out. Then, after 1-2 days, the test is repeated again. According to the instructions for use of the drug "Teturam", in the future you can take this remedy as maintenance therapy at 150 or 200 mg per day is enough a long period(up to 3 years).

Release form, composition

The active substance of this medication is disulfiram 0.15 g. Auxiliary components the following: potato starch, talc, aerosil, stearic acid.

The drug "Teturam", whose action is aimed at treating patients with alcohol dependence, is available in the form of tablets of 0.1, 0.15, 0.2 and 0.25 g. The package can contain from 10 to 50 pills.

Side effects

During the period of treatment with this remedy, the patient may experience a bitter taste in the mouth, headache, memory problems, and insomnia. Frequent side effects are allergic reactions - a rash on the body, urticaria, dermatitis.

In fact, the Teturam remedy for alcoholism is not as harmless as it seems at first glance. At long-term treatment with this medication, the patient may experience various violations activities of the cardiovascular, peripheral and central nervous systems. There may be problems with gastrointestinal tract, with cookies. In addition, people who previously suffered from such ailments as gastritis, inflammation of the stomach, ulcers and some other diseases may become aggravated by these ailments.

In some cases, when long-term use tablets "Teturam" patients may experience acute psychosis - a condition characterized by delusions of persecution, fear, anxiety. Also, the patient may be tormented by acute alcoholic hallucinosis. And these are various visions that a person perceives as reality. Among other things hallucinatory syndrome can smoothly turn into paranoid, and then into schizophrenia-like.

Contraindications

The drug "Teturam", reviews of which can be read below, is forbidden to be prescribed to people if they have such features and health problems:

Severe cardiovascular disease.

Liver failure.

Tuberculosis.

Epilepsy.

Diabetes.

Neuropsychiatric diseases.

Pregnancy and breastfeeding period.

With hypersensitivity to disulfiram.

Erosion of the gastric mucosa, ulcer.

Glaucoma.

Age up to 18 years.

With caution, the drug is prescribed to the elderly.

Positive feedback from people

The drug "Teturam" reviews are mostly flattering. People who consciously took this medication on the advice of a doctor really soon observed the effect: craving for alcohol passes, well-being improves. No side effects were observed in patients. However, as the patients themselves write, you need to come to this yourself, be prepared for the fact that you will never drink even a glass of vodka again. After all, if you force a person to encode, then there will be no sense from this. And if he himself reveals the desire and agrees, then this is another matter.

Negative feedback from people

In addition to the good ones, there are also bad reviews from people about the Teturam remedy. Unflattering reviews are left, oddly enough, not by the sick, but by their relatives, who in the wrong way wanted to cure their husbands and sons from such a misfortune as alcohol addiction. According to them, the drug has many side effects. Often people had attacks of suffocation, a rash appeared on the body, vomiting, shortness of breath, dizziness were observed. However, such symptoms arose through no fault of the Teturam remedy, the cause had to be sought in relatives who, with their cunning and tricks, simply harmed their loved ones. After all, you can not treat a person with these pills without informing him himself. Because, throwing these crushed pills to him, the relative only makes the patient worse. Since an alcoholic, not knowing that he is taking these pills, continues to drink, and alcohol and the Teturam drug are generally two incompatible things. And as a result, side effects are not long in coming. Therefore, read similar negative feedback stupid, because such actions of relatives can simply drive the patient to the grave.

Doctors' responses

The drug "Teturam" reviews from doctors receives unequivocally positive. Narcologists are satisfied with the effect of this remedy. They are confident that with its proper use, a person can get rid of alcohol addiction for a long time, and even forever. However, narcologists unanimously argue that "Teturam" - pills aimed at treating alcohol dependence - should never be purchased on your own without visiting a specialist who can prescribe individual scheme treatment. They also advise relatives of patients not to use prohibitive practices, such as pouring medication into food or drinks. And the best thing, according to narcologists, is to come to the doctor with a problem and, together with a specialist, discuss the topic, determine ways to solve the current situation. And most importantly - to bring to the consciousness of the alcoholic that he is sick and needs the help of a doctor.

The drug "Teturam": price

The cost of this medication is quite affordable for people. On average, Teturam tablets, the price of which depends on the number of pills in the package, on their dosage, as well as on pharmacy cheats, can be purchased for 80-120 rubles. If there are 30 tablets in a package, then the cost will be approximately 80-90 rubles. And if there are 50 pills, then, accordingly, the price will be higher - 110-120 rubles.

Now you know what Teturam tablets are for, what is their cost and people's reviews. We found out that it is forbidden to self-medicate, and even more so to sprinkle crushed pills on your sick relatives. After all, in the end it can end sadly.