How does Magnelis B6 differ from Magne? For whom the risk of harm is higher than the potential benefit

A lack of magnesium in the human body leads to a number of pathological conditions. Even serious health problems are sometimes solved by replenishing this substance. An effective remedy for eliminating magnesium deficiency is taking the drug Magne-B6. How and under what conditions should I take this medicine? What side effects and contraindications are important to know about before starting treatment with Magne-B6?

The role of magnesium in the human body

Magnesium is necessary for bones, heart, muscles, liver, kidneys. The total amount of this element in the human body is approximately 25 g. Its daily requirement for women is 300 mg, for men – 350 mg. Pregnant and nursing mothers should receive up to 925 mg (dose for expectant mothers) and 1250 mg (dose for women during lactation) of magnesium daily. What role does this element play in the body? Magnesium takes part in:

protein synthesis;
regulation of cell growth;
removal harmful substances;
normal functioning of the nervous system;
regulation;
prevention of urolithiasis;
phosphorus metabolism;
maintaining normal functioning of the heart muscle.

Release form of Magne B6

To treat magnesium deficiency, doctors may prescribe Magne B6 tablets. They are sold in packs of 30 and 50 pieces. Composition of Magne B6 tablets: 470 mg magnesium lactate dihydrate (corresponding to 48 mg magnesium), 5 mg pyridoxine hydrochloride. If necessary, the doctor prescribes a solution. contain 10 ml of the drug. Composition of Magne B6 solution: 10 mg pyridoxine hydrochloride, 186 m sodium lactate dihydrate, 936 mg magnesium pidolate (corresponding to 100 mg magnesium).

Indications for use Magne-B6

Since magnesium is essential for the normal functioning of all body systems, its deficiency affects the condition of almost all vital important organs. Magne-B6 is often prescribed for painful conditions when other medications are not effective or the causes of the disorder are not clear. How and why do they take magnesium B6? Let's consider for which pathologies of different body systems the use of this drug is indicated:

Cardiovascular system Magnesium is needed for abnormal heart rhythm, atherosclerosis, high cholesterol, ischemia, tendency to thrombosis, pain in the heart.
Nervous system disorders associated with increased irritability, insomnia, depression, and nervous tics are treated with Magne-B6.

During pregnancy

When planning a pregnancy, doctors recommend drinking Magne-B6. This will help prevent and eliminate some problems so that you can carry your baby without difficulty and keep him healthy. good condition mother's nervous system. Why is magnesium B6 needed during pregnancy? It is important for expectant mothers to take care of their bodies while carrying a child. useful microelements and substances. Magnesium is one of them. It is important for correct and normal development fetus

The nervous and other systems of a pregnant woman will not be able to function normally without a sufficient supply of Mg. This element can be absorbed from. Expectant mothers should include buckwheat in their diet, oatmeal, dried fruits, legumes. But as the fetus grows, a pregnant woman’s need for magnesium increases, so the doctor may prescribe her to take Mg B6.

How does maternal use of Magne-B6 affect the fetus? Medical studies have proven that this drug has no negative effects when correct use doesn't bring. However, this does not mean that pregnant women are allowed to drink it without a doctor’s prescription. Only a doctor after an examination can, if necessary, prescribe to the expectant mother magnesium to eliminate or prevent its deficiency. A gynecologist may prescribe Magne-B6:

when a woman complains of a high degree of irritability, constant mood swings, bad dream, stress;
with uterine tone to avoid spontaneous abortion;
with severe early toxicosis;
at ;
for spasms and intestinal colic;
with rapid fatigue;
with tingling and numbness of the limbs;
with malnutrition;
at ;
with intense fetal movement in the last months of pregnancy, because sometimes this indicates oxygen starvation fetus due to lack of magnesium.

For children

The doctor will prescribe Magne-B6 for the child if there is a severe deficiency of this element. Lack of magnesium in children is expressed in increased nervous excitability, insomnia, anxiety attacks, stress, muscle spasms, etc. After replenishing magnesium levels in children's bodies, their mothers noticed that children and teenagers became calmer, more attentive and slept better.

Instructions for use and dosage

Magne-B6 is available in tablets and solution (ampoules). Children under 6 years of age are prescribed magnesium in liquid form. Magne-B6 is also produced in the form of a gel in a tube. In this form, the drug is given to children after 3 years of age after meals. Children under 5 years old are given 5 g once a day, children from 5 to 12 years old - 10 g, and adolescents over 12 years old - 15 g. Never start drinking magnesium without consulting your doctor.

Film-coated tablets

How and how much to take Magne-B6? It is taken with food 2-3 times a day with 1 glass of water. Children over 12 and adults with severe magnesium deficiency drink 6-8 tablets. In this dosage form, the doctor prescribes the drug to children over 6 years of age who weigh 20 kilograms or more. Pediatricians prescribe 4-6 magnesium tablets per day for children. How to take Magne B6 during pregnancy? For expectant mothers with magnesium deficiency, the drug is prescribed to take 2 tablets three times a day, and to prevent a deficiency of this element - 2 tablets once a day.

Oral solution

To eliminate magnesium deficiency, adults are prescribed 3-4 ampoules, and children - 1-3 ampoules per day. In each case, the doctor will determine an individual daily norm for the patient. One ampoule contains 10 mg of magnesium B6. Treatment with the drug continues for up to 1 month. To extract the solution from the ampoule, you do not need to file it with a nail file, but only break off its tip with a sharp movement, having previously wrapped it in a cloth. The duration of magnesium intake is determined individually by your doctor.

Side effects and contraindications

Before you start taking Magne-B6, you need to familiarize yourself with the available contraindications and possible side effects of this medicine. In case of moderate renal failure, magnesium intake can provoke the development of hypermagnesemia. If a negative reaction to Magne-B6 occurs, you should stop drinking and consult a doctor for advice on this matter. TO side effects drugs include:

skin and other types of allergies;
nausea;
painful sensations in the abdomen;
vomit;
diarrhea;
paresthesia;
peripheral neuropathy.

When taking the drug while breastfeeding, it should be taken into account that magnesium passes into the baby’s body during feeding along with mother’s milk. If a person has a deficiency of calcium and magnesium, then the deficiency of Mg is first eliminated, and then Ca. The medicine contains sucrose, so diabetics should consult a doctor before starting treatment with this medication. Magne-B6 is contraindicated in the following conditions:

age up to 6 years (for taking tablets), up to 1 year (for taking solution);
phenylketonuria;
sensitivity to components of magnesium B6;
syndrome of impaired glucose absorption;
fructose intolerance;
concurrent use of levodopa;
sucrose-isomaltose deficiency;

An overdose of magnesium B6 does not cause toxic reactions during normal kidney function. However, there is a risk of drug poisoning in people with kidney failure. In this case, the following symptoms may occur: vomiting, low blood pressure, depression, coma, respiratory depression, cardiac arrest. In case of an overdose of the drug, rehydration (replenishment of fluid in the body) is indicated, and in the presence of renal failure, hemodialysis (blood purification using a “blood purification” device) artificial kidney»).

Approximate cost of the drug

The price of magnesium B6 medicine depends on the manufacturer. If the drug is foreign-made, then its cost will be more than its analogue from Russian manufacturers. Pharmacies may have different drug prices because they have different drug suppliers. For example, Magne-B6 in tablets costs 818 rubles for 50 pcs., and in ampoules – 395 rubles for 10 amps. 10 ml.

(img 4 = Analog Magne-B6 – Magnelis B6)

Analogs to the drug Magne-B6

What can replace Magne-B6 treatment? International name this medicine is Comb drug. Other drugs that are analogues are also registered under this name. of this medication. The Russian substitute for Magne-B6 is Magnelis B6. Pharmacies sell analogues of this drug: Hungarian Beres Plus, Polish Magnefar and Magvit v6, Ukrainian Magnikum. Magne-B6 substitutes have different prices, so buyers have a choice.

Magnesium is one of the most important chemical elements present in the human body. The drugs indicated in the title are intended to normalize the content of this substance. What to choose at the pharmacy Magnelis B6 or better Magnelis B6 Forte or Magnesium B6 Forte - what is the difference between them? I will consider it specifically for readers of “Popular about health.”

Pharmacological group

All three drugs: Magnelis B6, Magnesium B6 Forte and Magnelis B6 Forte are included in the group of magnesium-containing pharmaceutical drugs. They are intended to compensate for the body's current needs for magnesium and are sold without a prescription.

The second active ingredient in all three medicinal products is pyridoxine hydrochloride, better known as vitamin B6. It is important to understand that the drugs in question are not vitamin supplements. This active substance is intended solely to stimulate the absorption reactions of magnesium from the intestines.

Active substance

Magnelis B6 contains the following active substances: magnesium lactate, in the amount of 470 mg, as well as pyridoxine hydrochloride, the content of which is 5 mg.

Magnelis B6 forte contains magnesium in the form of citrate salt, the content of which is 618.43 milligrams. In addition, the drug contains double the amount of pyridoxine - 10 mg.

The composition of the drug Magnesium B6 Forte completely copies that of the drug Magnelis B6 Forte. It contains similar active substances in identical quantities. For this reason, both drugs can be considered as exact analogues of each other.

pharmachologic effect

Magnesium is one of the essential elements, involved in the processes of generation, transmission and transformation of electrical impulses in biological tissue. Its value is difficult to overestimate since magnesium deficiency is extremely severe and is accompanied by multiple electrolyte disturbances.

Magnesium regulates the electrical activity of the heart muscle. It is necessary for the balance of excitation and inhibition in the central nervous system. Besides, normal operation skeletal muscle growth will be impossible in conditions of deficiency of this mineral.

Magnesium also affects activity digestive system, being a regulator of peristaltic activity and at the same time a stimulator of adsorption reactions of basic food nutrients.

Indications for use of drugs

As a matter of fact, everyone has indications for use three drugs absolutely identical. Medicines are prescribed for conditions the cause of which lies in magnesium deficiency. Below is a sample list of indications:

Chronic stress;
Heart rhythm disturbances;
Spastic pathology of skeletal muscles;
Increased irritability;
Drowsiness and sleep disturbances.

It is important to note that the list of indications can expand significantly. You can take magnesium-containing drugs if you have a wide range of diseases, one way or another, accompanied by magnesium deficiency.

Contraindications for use

Contraindications to the use of Magnelis B6: phenylketonuria, age less than 6 years, intolerance to active or auxiliary substances, severe renal failure.

Magnesium B6 Forte and Magnelis B6 Forte, due to their high magnesium content, add the following conditions to the list of contraindications: phenylketonuria, the need to take levodopa, lactose or galactose intolerance.

Side effects

The negative consequences of taking all three drugs are the same. The difference lies only in the frequency of their occurrence. For medicines with a high magnesium content, it is higher than for Magnelis B6.

Taking medications may be accompanied by the following side effects: tingling in the fingertips, nausea, occasional vomiting, headache, weakness, increased blood pressure, manifestations of flatulence, tachycardia.

Differences

Magnelis B6 contains magnesium in the form of lactate. Other drugs include magnesium citrate. It is believed that the human body perceives magnesium lactate better and therefore the bioavailability indicator of this medicinal substance slightly higher - about 60 percent, versus 40.

However, the preparations Magnesium B6 Forte and Magnelis B6 Forte can “boast” of higher dosages of magnesium salts. It is expected that their use will be more effective. In addition, these medicines can be taken a little less frequently.

conclusions

Strictly speaking, there is no fundamental difference in all three medications. Magnesium lactate or citrate is not fundamentally important. The first is characterized by more high coefficient bioavailability, but due to the increased concentration of the second, the severity therapeutic action leveled out.

The price category of these drugs is also the same. Of course, imported medicines produced in the European Union will be approximately 2–4 times more expensive than domestic or Indian analogues, called generics (same active substances).

The fundamental differences between generics and originals lie in the composition of the excipients. In addition, one should also take into account the degree of chemical purity of the active component, which largely determines the severity of the pharmacological effects.

Magnesium preparations: properties, when indicated, contraindications, types and uses

The most important macronutrient, without it most of the biochemical reactions occurring in the human body are impossible. Translated from Latin, “magnesium” means great, and this indicates its indispensability for normal functioning organs and systems.

In recent years, magnesium preparations have become widely used not only for the treatment of diseases of the heart, nervous system, digestion, and leg cramps, but also for the prevention of a variety of diseases, improving well-being, reducing nervousness and increasing stress resistance.

Almost every biochemical reaction is controlled by magnesium; the synthesis of proteins, lipids and carbohydrates is not possible without it; it is part of enzymes and is involved in nerve impulses, regulates vascular tone and muscle tone. Magnesium has a calming effect on the nervous system, prevents the occurrence of seizures, reduces the severity of allergic and inflammatory reactions, promotes the proper functioning of the hemostatic and immune systems.

Figure: foods rich in magnesium (mg/100 g)

The main source of macronutrients is food, and with a balanced diet there is usually enough of it, however, physical activity, stress, overwork, and an overly active lifestyle can cause an increase in the need for it, which is difficult to “cover” with nutrition.

Scientists' studies show that almost half of the world's population is deficient in magnesium varying degrees, which inevitably affects general condition health, ability to work, resistance to infections, and with severe deficiency of the element, serious diseases occur.

These data prompted the creation of drugs based on magnesium, where the latter is associated with organic or inorganic acids, other minerals or vitamins, in particular group B. Understand the list of drugs currently offered for magnesium deficiency is not so simple, but choosing a suitable, effective and affordable one is even more difficult.

Patients come to the aid of specialists who offer detailed instructions on certain medications, and the Internet is flooded with a variety of information, sometimes from people who do not have special knowledge in the field of medicine and biochemistry. If the issue of taking magnesium has become, as they say, an issue, then it is better to entrust the choice and your health to a competent doctor who can recommend the right drug And the right dosage taking into account contraindications, which, by the way, also exist.

When and why are magnesium supplements prescribed?

Some situations or diseases can increase the need for vitamins and minerals, and deficiency can occur even when nutrition is more than adequate. These include:

Surgical interventions;
Diabetes;
Pathology of the digestive system, especially with bleeding, spasms;
Treatment with cytostatics, drugs with antacid properties;
Abuse of laxatives and diuretics;
Use of hormonal contraceptives;
Heavy sweating;
Alcoholism;
Frequent or chronic stress.

Reasons for prescribing magnesium supplements may include:

Proven through biochemical analysis blood magnesium deficiency, even if there are no symptoms as such;
Symptoms of magnesium deficiency - nervousness, increased nervous excitability, spasms of the digestive organs, tachycardia, weakness, muscle cramps and tingling in muscles;
Heart pathology (with arrhythmia, myocardial infarction);
Arterial hypertension;
Convulsive syndrome, epilepsy (for children too);
Pregnancy, especially in case of increased uterine tone or threat of miscarriage, with gestosis;
As a laxative - orally for constipation;
Inflammatory changes in the biliary tract;
Poisoning with heavy metals, barium.

As you can see, the indications for the use of Mg preparations are quite diverse, which once again shows the importance of the element and its participation in many biochemical processes. It is believed that an overdose practically does not occur when taking magnesium-containing products, because most medications taken orally contain a significantly smaller daily dose of a macronutrient, however, an overdose is still possible and has characteristic symptoms:

The disappearance of the knee reflex is the most common and earliest manifesting sign of excess magnesium;
Changes in the ECG - a decrease in heart rate, expansion of the ventricular complex, which indicates a slowdown in the conduction of impulses;
When the norm of magnesium in the blood is greatly exceeded, nausea and vomiting appear, hypotension develops, deep reflexes from the tendons disappear, double vision begins, and speech is impaired;
With severe hypermagnesemia, the respiratory center is depressed, conduction in the myocardium sharply slows down, which leads to cardiac arrest and death of the patient.

Before you start using any drug containing magnesium, you need to study the list of contraindications, although it is unlikely that you should prescribe treatment yourself without consulting a doctor. Contraindications include:

Increased individual sensitivity to any component of the drug;
Profound renal failure;
Phenylketonuria and some hereditary metabolic syndromes;
Children under 6 years of age (relative contraindication);
Myasthenia;
Dehydration, heavy sweating;
Intestinal obstruction, acute inflammatory changes in the intestines, bleeding - with oral administration of magnesium sulfate;
Rare pulse, atrioventricular heart block.

Review of magnesium-containing drugs and features of their use

Before starting treatment or prevention of magnesium deficiency, it is important to know the rules for taking these medications:

Thus, the combination of magnesium with vitamin B6 is considered very successful, since these substances mutually enhance their effectiveness, and the vitamin improves the absorption of the macronutrient, maintains its intracellular concentration and provides a better therapeutic result.
Considering common paths absorption in the intestines, magnesium is not recommended to be consumed simultaneously with calcium and iron supplements. In this case, there will be an equally low effect from both magnesium and calcium with iron. If such complex treatment is necessary, the doctor will prescribe how best to differentiate between medications and what intervals between doses are best observed.
Magnesium supplements should not be taken on an empty stomach or between meals, as this can cause abdominal pain and stool upset. They should be washed down with water, not milk.

Products with magnesium are available in tablets, ampoules for intravenous or intramuscular administration, and in powder form for oral administration. The specific dosage form is determined by the indications for treatment. For long-term use, tablets are usually prescribed; in acute cases such as a hypertensive crisis, a solution will be used, and in case of digestive problems, a powder will be used before manipulation of the abdominal organs.

Pharmacies offer a fairly wide list of medications with magnesium as the main component, as well as in combination with vitamin B6 or potassium. They differ not only in bioavailability, composition, dosage, but also in price, which is also considered a significant factor in choice. In this case, price often means the quality and effectiveness of the drug, which can be confirmed by patients who have tried medications of different compositions from different manufacturers.

Bioavailability, that is, the level of digestibility and, accordingly, effectiveness, depends on the composition of the drug and the element or substance with which magnesium is associated in it. For example, there are inorganic magnesium salts - sulfate, chloride, as well as oxides and hydroxides. Organic include citrate, lactate, magnesium gluconate, compounds with salicylic acid and ascorbic acids and others.

Information regarding the absorption of organic and inorganic magnesium compounds varies and is even contradictory. Thus, some researchers refute the common point of view according to which organic salts are absorbed better, citing weighty arguments; therefore, when choosing, it is not always necessary to rely on the composition. For example, magnesium sulfate is considered the most poorly absorbed, but it can successfully combat constipation when taken orally and hypertensive crises when injected.

The criteria for choosing the best magnesium preparations often include the manufacturer, the composition and concentration of the macroelement in the tablet, and the price. The manufacturing company is important from the position that the quality of raw materials, the safety of the drug and its bioavailability depend on it, therefore it is perceived by many patients as a quality publicity stunt Recommendations regarding a particular company should still be heeded.

Not every one of us thinks about the fact that the dosage indicated on the package does not mean the content of pure magnesium in the tablet. Some manufacturers honestly indicate this figure, others do not, and then the buyer should calculate it himself, remembering the school chemistry course and clarifying daily requirement in a macronutrient.

Organic magnesium salts are considered quite effective and have additional positive influence on the body. Among them:

Magnesium citrate - derivative citric acid- has high bioavailability, can improve metabolism in general due to activation respiratory processes and energy production in cells;
Magnesium malate - a salt of malic acid - also boasts high availability for cells, a positive effect on cellular respiration and metabolism;
Magnesium aspartate - a salt of aspartic acid - bioavailability is good, and aspartic acid takes an active part in nitrogen metabolism;
Magnesium orotate is a drug with good bioavailability, orotic acid improves metabolic processes and growth;
Magnesium lactate is a lactic acid derivative with good bioavailability.

Inorganic Mg-based substances include sulfate (sulfuric acid salt) and metal oxide. Sulfate is used in powder form as a remedy for constipation and to cleanse the intestines before operations and studies, during intravenous or intramuscular injection has a hypotensive effect. Not used to eliminate macronutrient deficiency. Magnesium oxide is very poorly absorbed, but is quite effective in combating constipation.

Preparations containing magnesium and calcium at the same time cannot have the desired effect due to the fact that these metals are not absorbed together, therefore, the appropriateness of their use is questionable. If you need to make up for the deficiency of both, then it is better to use the elements separately and drink them at different times.

The so-called magnesium chelate compounds are considered relatively new. which are produced abroad, in particular in the USA. This magnesium is highly available to the body, but also differs high cost drugs, since not every pharmaceutical manufacturer can create such a compound.

Many pharmacies visitors try to save on medicines by choosing cheap domestic analogues or generic drugs instead of original ones imported medicines. When calculating the number of French or American-made tablets to be taken for a course of treatment, an impressive amount emerges that will have to be spent on the drug. The financial side of the issue often becomes decisive when choosing.

At the same time, a high price is not only a consequence of advertising campaigns, decent salaries for pharmaceutical production workers, the world-famous name of the manufacturing company, etc. For at a high price clinical trials are hidden, high accuracy dosing, safe raw materials for the production of medicines. And few can deny that the effects, including side effects, are sometimes very different for cheap analogues and original drugs well-known companies.

Magnesium sulfate (magnesium sulfate)

One of the “oldest” products containing magnesium is considered magnesium sulfate in powder and ampoules. Powders of 10 and 20 grams are used exclusively internally and have a choleretic and laxative effect. In addition, it can be used as an antidote for intoxication with heavy metal salts.

The effect of the drug lasts up to 6 hours, and the onset of the effect occurs already half an hour after administration. The reason for the prescription may be constipation, inflammation of the gallbladder and biliary tract, as well as cases when it is necessary to prepare the digestive organs for probing or other manipulations.

As a laxative, magnesium sulfate is consumed at night or half an hour before meals, dissolved in half a glass warm water. At chronic constipation You can do enemas with magnesium. In order to obtain a choleretic effect, use a tablespoon of dissolved magnesia three times a day. When probing the duodenum, the drug is administered through a probe.

Side effects are rare and are more often associated with abdominal discomfort, exacerbation inflammatory processes in the digestive organs, disorders electrolyte balance. In severe cases, bradycardia, hypotension, shortness of breath and vomiting cannot be excluded. To exclude side effects, the drug cannot be taken continuously and systematically, as well as to compensate for magnesium deficiency due to ineffectiveness.

Magnesia sulfate is not compatible with calcium-containing preparations, ethyl alcohol in large quantities, with some antibiotics and hormones derived from salicylic acid.

Unlike powder, magnesium sulfate in ampoules can be used to eliminate magnesium deficiency or prevent it in patients with parenteral nutrition, as well as taking contraceptives, some types of diuretics, with severe sweating.

When providing ambulance and emergency care it is used to restore heart rhythm, prevent arrhythmia during a heart attack, treat hypertensive crises, convulsions, late gestosis in pregnant women, heavy metal intoxication.

Intravenous drip courses are prescribed for cases of threatened miscarriage or increased uterine tone, but only in a hospital setting. The introduction is carried out very slowly, using special devices that allow you to set the required number of magnesium drops per minute. Despite the relative safety of this magnesium drug, it is prescribed to pregnant women with caution, and nursing mothers should stop feeding during the period of treatment.

The introduction of magnesium sulfate should be carried out slowly to avoid unwanted effects in the form of a feeling of heat, hot flashes, dizziness. When injected into a muscle, the drug is painful. Intravenous use is carried out with the patient in a supine position, and the dropper can “drag on” for hours.

For children, indications for prescribing magnesium sulfate may be convulsive syndrome, including against the background of glomerulonephritis. In this case, treatment begins with 20-40 mg per kilogram of body weight intramuscularly. In the first year of a baby’s life, the drug is prescribed with caution and only under the control of the level of magnesium in the blood and tendon reflexes.

An overdose of magnesium causes depression respiratory center and cardiac activity. Acts as an antidote calcium chloride, injected into a vein. In case of lung dysfunction, they improve artificial ventilation, according to indications, hemodialysis is performed and symptomatic treatment is prescribed.

Magnesium with Vitamin B6

Perhaps the best drugs available to a wide range of consumers are combinations of Mg with vitamin B6. In particular, it is widely known in the Russian Federation and has proven itself well Magne B6 French company Sanofi. This original, but relatively expensive drug contains organic magnesium salt (lactate) and vitamin B6, the mass of ionized magnesium is 48 mg per tablet. In ampoules the weight of pure magnesium is one hundred milligrams.

Magnesium with B6 is prescribed for emotional instability, irritability, anxiety syndrome, increased fatigue, sleep disorders. Tachycardia in the absence organic damage organ may also indicate the need for treatment. The drug is used for cramps in the legs and tingling sensation in the muscles, cramps in the abdomen.

The recommended duration of treatment is one month. If there is no improvement during this period, then you should switch from monotherapy to the use of drugs from other groups or begin to search for other possible causes of the pathology.

The experience of using Magne B6 in pregnant women did not show any negative influences on a growing fetus, so it is considered safe at any stage, however, nursing mothers should refrain from using the medicine or stop feeding.

Magnesium with vitamin B6 is prescribed to adults and children over six years of age. You should take 6 to 8 tablets a day with meals and a large glass of water. If diarrhea, abdominal pain, or an allergic reaction occurs, treatment is stopped.

For the prevention and treatment of mild forms of magnesium deficiency, tablets are prescribed, and in severe cases, injection of a solution of Mg lactate with vitamin B6 into a vein is indicated. Magne B6 forte contains a double dose of the macronutrient.

In the list of analogues of the “French” - Magnefar B6,magwit, Magnerot. Magnefar B6 is produced by the Polish company Biopharm and has similar indications and contraindications, however, the proportion of pure magnesium in the tablet is somewhat lower, as is the cost of the medicine. Magvit is a product of the Minskintercaps plant, which limited itself to indicating only the concentration of magnesium citrate in one capsule. The price of Magvit is more than affordable and almost 10 times lower than its French counterpart.

Magnesium and the heart

Magnesium supplements for the heart are considered panangin And asparkam. The first is a mixture of organic potassium and Mg salts that affect metabolic processes in the heart muscle. The reasons for its use are considered to be heart failure, heart attack, rhythm disorders, and poor tolerance of cardiac glycosides. Due to the low magnesium content in one tablet, the drug is unlikely to be indicated for eliminating magnesium deficiency.

Panangin is available in tablets, which can be bought without a prescription, and ampoules, sold only with a doctor's prescription. Tablets are taken three times a day, 1-2 pieces, after meals, the duration of treatment is determined by the doctor. Panangin is injected into a vein slowly, diluted with a glucose solution.

The list of magnesium preparations includes the well-known asparkam, which has been prescribed to cardiac patients for many years. It contains potassium and magnesium salts of aspartic acid. Indications for treatment include a deficiency of macroelements in the body, complex therapy cardiac ischemia, rhythm disturbances, prevention of poisoning with cardiac glycosides.

Asparkam is used 2 tablets three times a day for therapeutic purposes and one tablet for prevention. The duration of treatment is determined by the doctor. In case of overdose, signs of hypermagnesium and hyperkalemia appear - hypotension, facial flushing, bradycardia, etc.

Chelated forms

In Russia, Mg chelate from NSP (USA) is still widely distributed; the manufacturing company is equipped with its own laboratory with high quality standards and has documents confirming this very quality of the drugs. For the production of medicines, plant materials are used, and magnesium is produced in the form of chelated compounds. The drug is sold as a biological food additive.

So, we examined only the most popular drugs containing magnesium. The choice is up to the buyer, but one must remember that a cheap price can result in taking useless drugs, and analogues (generics) known drugs can carry more high risk negative consequences And side effects at lower efficiency.

When purchasing magnesium drugs at a pharmacy, you should not blindly follow advertising or choose a cheaper analogue, but be guided by the doctor’s opinion and official data on the safety and bioavailability of a particular drug. In some cases, laboratory monitoring of electrolyte metabolism may be necessary, which allows timely detection of excess of normal concentrations of both magnesium and potassium in the body.

Particular care must be taken when purchasing dietary supplements containing macroelements, since neither accurate information There may be no information about the content of magnesium ions, nor a list of side effects and contraindications, which means that taking them can be fraught with various disorders.

Video: magnesium deficiency, nutrition, medications

Hello girls, I was in storage for several days, today the doctor let me go home until Monday, I explained how to treat myself at home, I was in bed with abdominal pain for 18 weeks, I was told to drink magnesium B6, I already wanted to buy it myself, I drank Magnelis for a short period of time, I didn’t understand, it helped Whether it’s for me or not, a girl read here and wrote that only Magne B6 helps her, and no other analogues. So I went to the pharmacy, these drugs cost 167 rubles, 364 rubles, 600, and 900 in a row)))) I asked what the actual difference was? To which they told me no, so I took the cheapest one. It’s the same story with calcium D3, so I took the most common one, what do you think? Is there any difference?? My leg drags all day long, the doctor says I don’t have enough of these substances...

Magnesium B6 is a vitamin complex (dietary supplement) aimed at maintaining nerve impulses and metabolism. Magnesium and vitamin B6 are found in every body, but if there is a deficiency, this medicine is prescribed. This complex will help the body cope with stressful moments in life and is useful for all ages.

What is it needed for?

A vitamin-mineral complex is needed to maintain the body as a whole. Without it, calcium is also not absorbed. If there is a lack of this component, causeless fatigue and irritability appear, that is, it is bad for the entire body, and especially the nervous system.

The drug is prescribed for stress, during pregnancy, for the prevention of neuroses, when planning pregnancy and in the early stages, as well as with increased uterine tone, reduces high blood pressure, from nerves.

Composition, release form, cost

Available in ampoules and tablets. Consists of 2 elements: magnesium lactate dihydrate plus vitamin B6.

1 tablet contains 48 mg of magnesium and 5 mg of pyridoxine hydrochloride. Their color is oval and white. Available in boxes of 36 and 60 tablets. 1 ampoule contains 100 mg of magnesium and 10 mg of pyridoxine hydrochloride. Packages contain 10 ampoules. It has been proven that the liquid drug is best absorbed by the body. The contents can be either drunk, diluted with water, or given injections.

Manufacturer: Evalar, Akvion, Sistmatik (Russian).

How much does the drug cost? The cost of tablets (caps.) at the pharmacy is from 300 rubles for 50 pieces. And 10 ampoules from 250 rubles. Prices vary across the country.

Analogues are cheaper

There are quite a lot of substitutes and drugs similar to this one. Namely: Magnelis, Magne B6, Doppelhertz, magnesia, Complivit (a preparation with many vitamins, including magnesium), Magnelis, Panangin, Solgar vitamin complex, Blamomax (B vitamins), motherwort forte. Some are cheap and others are expensive. It depends who produces it.

Some of these preparations also contain other vitamins. Magne B6 and Magnesium B6 are the same thing, but the manufacturers are different. And the second one is much cheaper. They do not differ in action. But replacing the drug should be under the supervision of a doctor. Maznesium is presented as effervescent tablets.

It is very good to take magnesium B6 and glycine. This combination has a beneficial effect on the nervous system.

What is the difference between magnesium and vitamin B6 preparations?

They complement each other perfectly. Magnesium in the body is a source of energy and proper functioning of all metabolic processes. Vitamin B6 also affects the nervous system, but through the synthesis of protein, hemoglobin and enzymes. It promotes the absorption of proteins and fats. Why talk about differences, it’s important to talk about additions.

Instructions for use

Adults, both women and men, need to take 3-4 tablets 2-3 times a day. You can take it for a long time.

If used in ampoules, then 3-4 ampoules. Dissolve the contents of the ampoule in a glass of water and drink. Drink the solution 2-3 times a day.

You need to take the tablets after meals (so they are better absorbed) and wash them down big amount water.

Instructions for magnesium in 6 forte

Indications are the same as usual: 3-4 tablets or ampoules per day.

During pregnancy and breastfeeding how to take?

If you are breastfeeding (lactation), it is not advisable to take this drug, as it is excreted in breast milk. It is also not recommended for infants under 12 months.

In tablets, prescription for adults

The medicine can be taken in tablet form for children over 6 years of age. The course of treatment is prescribed by the doctor. Typically the daily dose is 2-4 tablets during or after meals.

Adults take 3-4 tablets per day with a glass of water. On average, they take up to 30 days.

For children dosage

It is allowed to be given in ampoules to infants from 12 months. It is necessary to give 10-30 mg for each kilogram of the child’s weight. If you need to change the drug, be sure to consult your doctor. He will also tell you how much to drink over time. The drug is obtained as a syrup, as it has a sweetish taste.

Reviews, contraindications

The use of the medicine is contraindicated in case of renal failure, impaired glucose absorption, as well as intolerance to the components.

There are many reviews about this medicine, mostly positive. Sometimes you can meet allergic reactions in children. Some doctors, for example, Komarovsky, advise taking magnesium for life, so the necessary daily dose the body will not take it. The official website will provide detailed instructions, which also include a photo of the medicine. You can feel the benefits of vitamins after a week of taking them. There you can also find a children's gel containing a vitamin complex.

What foods do contain magnesium?

How much depends on nutrition. Buckwheat, soy, almonds, rice, bran, spinach, eggs, oatmeal and other foods containing potassium and magnesium are rich in essential microelements. B6 alone will not do the job, but it should be taken as a complex for hair growth.

Sometimes pharmacies hold a “be healthy” promotion and sell vitamin complexes cheaper.

Side effects

The drug rarely has Negative influence on the body. The most common is allergies. IN in rare cases There is gas formation and nausea.

Compatibility with other drugs, alcohol

Magnesium B6 is not compatible with taking levodopa. The absorption of the drug and its simultaneous use with calcium worsens. Alcohol flushes it out of the body. For obvious reasons, taking the medicine with alcohol becomes ineffective.

Magne B6

is a drug that replenishes magnesium deficiency and

vitamin6

in the human body, regardless of the reasons that provoked it. The drug is used for the prevention and treatment of magnesium deficiency and related disorders, such as sleep disorders, nervous excitability, mental or physical

overwork

Muscle pain and spasms, anxiety attacks with hyperventilation

Composition, release forms and varieties of Magne B6

Currently, the drug is available in two varieties -

Magne B6Magne B6 forte

On pharmaceutical market in some CIS countries (for example, in Kazakhstan) Magne B6 forte is sold under the name

Magne B6 Premium

The difference in names is due only to the marketing work of the manufacturing company, since Magne B6 Forte and Magne B6 Premium are absolutely identical drugs. Magne B6 and Magne B6 forte differ from each other only in the dosage of active ingredients, of which the second preparation contains twice as much. Otherwise, there are no differences between the varieties of the drug.

Magne B6 is available in two dosage forms:

Tablets for oral administration; Oral solution. Magne B6 forte is available in a single dosage form - tablets for oral administration.

The composition of tablets and solution of both varieties of Magne B6 as active ingredients contains the same substances - magnesium salt and vitamin B6, the amounts of which are shown in the table.

Active components Magne B6 tablets (quantity per tablet)	Active components of Magne B6 forte tablets (amount per tablet)	Active components of Magne B6 solution (amount per ampoule)
Magnesium lactate dihydrate 470 mg, corresponding to 48 mg of pure magnesium	Magnesium citrate 618.43 mg, which corresponds to 100 mg of pure magnesium	Magnesium lactate dihydrate 186 mg and magnesium pidolate 936 mg, equivalent to 100 mg pure magnesium
Vitamin B6 in the form of pyridoxine hydrochloride – 5 mg		Vitamin B6 in the form of pyridoxine hydrochloride – 10 mg

Thus, as can be seen from the table, one tablet of Magne B6 forte contains the same amount of active substances as one full ampoule of solution (10 ml). And Magne B6 tablets contain two times less active substances compared to a full ampoule of solution (10 ml) and Magne B6 forte. This should be kept in mind when calculating dosages for taking the drug.

Auxiliary components of both varieties of Magne B6 are also reflected in the table.

Excipients of Magne B6 tablets	Excipients of Magne B6 forte tablets	Excipients of Magne B6 solution
Titanium dioxide	Hypromellose	Sodium disulfite
Carnauba wax	Titanium dioxide	Sodium saccharinate
Acacia gum	Lactose	Cherry caramel flavor
Kaolin	Macrogol	Purified water
Carboxypolymethylene	Magnesium stearate
Magnesium stearate	Talc
Sucrose
Talc

Magne B6 and Magne B6 forte tablets have the same oval, biconvex shape and are painted in a shiny white color. Magne B6 is packaged in cardboard boxes of 50 pieces, and Magne B6 forte - 30 or 60 tablets.

Magne B6 oral solution is bottled in sealed ampoules of 10 ml. The package contains 10 ampoules. The solution is colored brown transparent and has characteristic smell caramel.

Therapeutic effect

Magnesium plays important role in different physiological processes in the body, ensuring the process of transmitting impulses from nerve fibers to muscles, as well as contractions of muscle fibers. In addition, magnesium reduces the excitability of nerve cells and ensures the activation of a number of enzymes, under the influence of which cascades of important biochemical metabolic reactions occur in various organs and fabrics.

Magnesium deficiency can develop due to the following reasons:

Congenital pathology of metabolism, in which this element is poorly absorbed in the intestines from food; Insufficient intake of the element into the body, for example, with malnutrition, starvation, alcoholism, parenteral nutrition; Impaired absorption of magnesium in digestive tract at chronic diarrhea, gastrointestinal fistulas or hypoparathyroidism; Loss of large amounts of magnesium due to polyuria (urine excretion in a volume of more than 2 liters per day), taking diuretics, chronic pyelonephritis, renal tubular defects, primary hyperaldosteronism or the use of Cisplastin; Increased need for magnesium during pregnancy, stress, taking diuretics, as well as with high mental or physical activity. Vitamin B6 is a necessary structural element of enzymes that ensure the occurrence of various biochemical reactions. Vitamin B6 is involved in the metabolic process and in the functioning of the nervous system, and also improves the absorption of magnesium in the intestines and facilitates its penetration into cells.

Magne B6 - indications for use

Both varieties of Magne B6 have the same following indications for use: 1. Identified and supported by data laboratory tests Magnesium deficiency, in which a person has the following symptoms: Irritability; Sleep disturbances; Spasms of the stomach and intestines; Palpitations; Fatigue; Spasms and pain in the muscles; Tingling sensation in the muscles and soft tissues. 2. Prevention of the development of magnesium deficiency against the background increased need in this element (pregnancy, stress, malnutrition, etc.) or its increased removal from the body (pyelonephritis, taking diuretics, etc.).

Magne B6 - instructions for use

Magne B6 tablets

Magne B6 in tablet form is intended only for adults and children over 6 years of age. Children under 6 years of age should be given the drug in the form of an oral solution.

The tablets must be taken with meals, swallowed whole, without biting, chewing or crushing in any other way, and with a glass of still water.

The dosage of Magne B6 is determined by the person’s age:

Adults and adolescents over 12 years old - take 6 - 8 tablets per day (2 tablets 3 times a day or 4 tablets 2 times a day); Children over 6 years old weighing more than 20 kg - take 4 - 6 tablets per day (2 tablets 2 – 3 times a day). The indicated daily amount of Magne B6 is divided into 2 - 3 doses per day, keeping approximately equal intervals between them.

The duration of therapy is determined by the rate of disappearance of symptoms of magnesium deficiency and normalization of its concentration in the blood. In case of magnesium deficiency, treatment is stopped after the level of this element in the blood reaches normal values. When taking Magne B6 for prophylaxis, the course of therapy is usually 2–4 weeks.

Magne B6 in ampoules

Each ampoule contains 10 ml drinking solution, which must be taken orally, after diluting it in half a glass of still water. Magne B6 solution is best taken with meals.

The ampoules with the solution are self-breaking, so you do not need to cut the glass to open them. To safely open the ampoule, you need to place it in a thin, clean cloth. Then, with the fingers of one hand, hold the ampoule through the fabric in a vertical position, and with the other, break off the tip that is at the top, making a sharp movement to do this. After this, the ampoule is freed from the tissue, turned over with the open end down so that the solution is poured into a mug, glass or other container. However, in order for the solution to flow freely from the ampoule into the glass, it is necessary to break off the second sharp tip located at the other end of the container. To do this, break off the tip with exactly the same sharp movement, carefully holding it with your fingers so that it does not accidentally fall into the glass. After removing the second sharp tip of the ampoule, the solution will flow out quickly and freely.

After the entire solution from the ampoule has flowed into the glass, you should dilute it with approximately 100 ml of still water and drink immediately. The ampoule with the solution must be opened immediately before taking the drug. You cannot open the ampoule in advance, pour the solution into a glass and drink it after a few hours or days.

The dosage of Magne B6 solution is determined by age:

Adults and adolescents over 12 years old - take 2 - 4 ampoules per day (1 ampoule 2-3 times a day or 2 ampoules 2 times a day); Children aged 6 - 12 years - take 1 - 3 ampoules per day (1/3 - 1 ampoule 3 times a day); Children aged 1 - 6 years - take 1 - 4 ampoules per day, having previously calculated the exact dosage based on body weight, based on the ratio of 10 - 30 mg magnesium per 1 kg of weight. General daily dosage The solution must be divided into 2 - 3 doses, trying to maintain equal intervals between them.

Magne B6 solution can be given to children starting from the age of 1 year, but provided that their body weight is at least 10 kg. If the child is already one year old, but weighs less than 10 kg, then it is not advisable to give him Magne B6 in the form of a solution.

The duration of the course of using Magne B6 solution is determined by the rate of normalization of its concentration in the blood and the disappearance of symptoms of magnesium deficiency. If Magne B6 solution is taken to prevent magnesium deficiency (for example, during pregnancy), then the course of use is usually 2 to 4 weeks. If the drug is taken to compensate for magnesium deficiency, then the course of therapy continues until the concentration of this element in the blood reaches normal values.

Magne B6 forte – instructions for use

Magne B6 forte tablets are intended for use by adults or children over 6 years of age, provided their body weight is more than 20 kg. If a child is over 6 years old, but his body weight is less than 20 kg, then he cannot take Magne B6 Forte. In this case, the child must be given the drug in the form of an oral solution.

The tablets must be taken orally during meals, swallowed whole, without biting, chewing or crushing in any other way, but with a glass of still water.

Dosages of Magne B6 forte are determined by the person’s age:

Adults and adolescents over 12 years old - take 3 - 4 tablets per day (1 tablet 3 times a day or 2 tablets 2 times a day); Children 6 - 12 years old - take 2 - 4 tablets per day ( 1 tablet 2-3 times a day or 2 tablets 2 times a day). The total indicated daily dosage of the drug must be divided into 2 - 3 doses.

The average duration of treatment is 3 – 4 weeks. If the drug is taken to eliminate magnesium deficiency, then the course of treatment is completed when, according to the results of laboratory tests, the concentration of this element in the blood is normal. If the drug is taken for prophylactic purposes, the course of treatment is 2–4 weeks.

special instructions

In case of moderate and mild renal failure, the drug should be used with caution, constantly monitoring the level of magnesium in the blood, since due to the low rate of excretion of the drug by the kidneys, there is a risk of developing hypermagnesemia (increased concentration of magnesium in the blood). If renal failure is severe and CC (according to the Rehberg test) is less than 30 ml/min, then Magne B6 is contraindicated for use in any form (both tablets and solution).

Children aged 1 – 6 years should be given Magne B6 only in solution form. Children over 6 years of age who weigh more than 20 kg can be given Magne B6 in tablet form (including Magne B6 forte). But if a child over 6 years old has a body weight of less than 20 kg, then he cannot be given the drug in tablets; in this case, a solution should be used.

If a person has a severe degree of magnesium deficiency, then before taking Magne B6, several intravenous injections of appropriate drugs should be made.

If a person has a combined deficiency of calcium and magnesium, then it is first recommended to take a course of Magne B6 to eliminate the deficiency of magnesium, and only after that start taking various biologically active additives and drugs to normalize calcium levels in the body. This recommendation is due to the fact that in conditions of magnesium deficiency, calcium entering the body is very poorly absorbed.

If a person often uses alcoholic drinks, laxatives or constantly endures heavy physical or mental stress, then he can take Magne B6 to prevent magnesium deficiency in the body without any special tests. In this case, the usual preventive course is 2–3 weeks, and it can be repeated every 2–3 months.

Magne B6 solution contains sulfite as excipients, which can increase the manifestations of allergies, which must be kept in mind and taken into account by people prone to hypersensitivity reactions.

When taking the drug in high dosages(more than 20 tablets of Magne B6 forte and more than 40 tablets or 40 ampoules of Magne B6) for a long time there is a risk of developing axonal neuropathy, which is manifested by numbness, impairment pain, tremors of the arms and legs and gradually increasing loss of coordination of movements. This disorder is reversible and disappears completely after discontinuation of the drug.

If, despite taking Magne B6, the symptoms of magnesium deficiency (excitability, muscle cramps, irritability, insomnia, fatigue) do not decrease or go away, then you should stop using the drug and consult a doctor to clarify the diagnosis.

Impact on the ability to operate machinery

Neither tablets nor solution of Magne B6 affect a person’s ability to control mechanisms, therefore, while taking any form of the drug, you can exercise various types activities requiring high speed reactions and concentration.

Overdose

An overdose of Magne B6 is possible, but, as a rule, this occurs against the background of renal failure. In people who do not suffer from kidney disease, an overdose of Magne B6 is usually not observed.

Symptoms of an overdose of Magne B are the following:

Decreased blood pressure; Nausea; Vomiting; CNS depression; Decreased severity of reflexes; ECG changes; Respiratory depression up to paralysis; Coma; Cardiac arrest; Anuria (lack of urine). To treat an overdose of Magne B6, it is necessary to give a person diuretics in combination with large amounts of water and rehydration solutions (for example, Regidron, Trisol, Disol, etc.). If a person suffers from renal failure, then hemodialysis or peritoneal dialysis is necessary to eliminate the overdose.

Interaction with other drugs

Magne B6 reduces the severity of the therapeutic effect of Levodopa. Therefore, it is recommended to avoid the combined use of Levodopa with Magne B6, however, if there is an urgent need to take these drugs, then peripheral dopa decarboxylase inhibitors (Benserazide, etc.) should also be prescribed. In other words, the combination of Levodopa and Magne B6 is possible only with the additional use of a third drug from the group of dopa decarboxylase inhibitors.

Calcium and phosphate salts impair the absorption of magnesium in the intestine, so they are not recommended for use simultaneously with Magne B6.

Magne B6 reduces the absorption of tetracyclines (Tetracycline, Oxytetracycline, Chlortetracycline, Doxycycline) in the intestine, so an interval of at least 2 to 3 hours should be maintained between taking these drugs. That is, Magne B6 should be taken either 2–3 hours before or 2–3 hours after taking a tetracycline antibiotic.

Magne B6 weakens the effects of thrombolytic agents (Streptokinase, Alteplase, etc.) and anticoagulants (Warfarin, Thrombostop, Phenilin, etc.), and impairs the absorption of iron preparations (for example, Fenyuls, Ferrum Lek, Sorbifer Durules, etc. .).

Magne B6 during pregnancy

Magne B6 is approved for use during pregnancy, since long-term observations and experimental studies did not reveal any negative impacts this drug on the fetus and on the mother.

Magne B6 is widely prescribed to pregnant women, since its benefits are obvious in almost all cases. Thus, magnesium, which is part of the drug, helps reduce excitation in the central nervous system, due to which the woman becomes calmer, nervousness, moodiness, mood swings, etc. disappear. Of course, the calmness of the expectant mother has a positive effect on the child.

In addition, magnesium eliminates muscle spasms, cramps, tics and associated unpleasant pulling sensations or pain in the lower abdomen, lower back, legs, etc. The drug also reduces the tone of the muscular layer of the uterus, thereby eliminating the so-called “hypertonicity” and the associated threat of miscarriage.

Vitamin B6, also included in the preparation, is necessary for normal height and development of the fetal nervous system and heart. Against the background of vitamin B6 deficiency, the fetus may develop malformations of the heart, its valve apparatus or the central nervous system. Magne B6 prevents similar complications pregnancy.

Thus, it is obvious that Magne B6 improves not only physical state pregnant woman and eliminates uterine hypertonicity, but also has a positive effect on emotional background and relieves unnecessary stress.

However, Magne B6 is prescribed to almost all pregnant women in fairly long courses, even if the woman does not have a threat of miscarriage, hypertension, tics, etc. This practice is due to the fact that during pregnancy the consumption and need for magnesium doubles, and quite often a woman does not receive required quantity microelement with food or vitamins, as a result of which she develops certain symptoms of microelement deficiency. Therefore, doctors consider the prophylactic administration of Magne B6 to be justified in order to prevent deficiency of magnesium and vitamin B6.

remember, that Symptoms of magnesium deficiency are:

Spasms, cramps, muscle tics, nagging pain in the lower back or lower abdomen; Dizziness, headaches, sleep disorders, irritability; Arrhythmia, high or low blood pressure, palpitations, heart pain; Nausea, vomiting, alternating constipation with diarrhea , cramps and pain in the abdomen; Tendency to swelling, low temperature body, constant chilliness. Similar symptoms are found in a large number of pregnant women, which allows us to conclude that magnesium deficiency is widespread during pregnancy. Knowing this state of affairs, gynecologists managing pregnancy prescribe Magne B6 to women in regular courses of 3 to 4 weeks, even if this particular pregnant woman has not yet fully developed symptoms of magnesium deficiency.

During pregnancy, it is optimal to take 2 tablets of Magne B6 or 1 tablet of Magne B6 forte 3 times a day with meals.

Magne B6 for children

Magne B6 is prescribed to children to eliminate or prevent magnesium deficiency. In some cases, the drug is prescribed “just in case”, since clinical observations have shown that taking Magne B6 has a positive effect on the general condition of the child, who sleeps better, becomes calmer, more attentive, more diligent, and is less likely to be capricious and nervous. Of course, such effects are assessed very positively by both parents and doctors -

pediatricians

And therefore Magne B6 is often prescribed to children who do not have magnesium deficiency, but adults want to make them calmer and less excitable. Despite the beneficial effects of Magne B6, it is not recommended to use the drug without a doctor’s prescription and supervision, especially for children 1–6 years old.

Magne B6 is available in two dosage forms - tablets and oral solution. Tablets can only be given to children over 6 years old, provided that their body weight has reached 20 kg or more.

The dosage of Magne B6 for children is determined by their age and body weight:

Children aged 1 – 6 years with a body weight of 10 – 20 kg– take 1 – 4 ampoules per day, having previously calculated the exact dosage based on body weight, based on the ratio of 10 – 30 mg of magnesium per 1 kg of weight per day; Children aged 6 – 12 years, weighing more than 20 kg– take 1 – 3 ampoules per day (1/3 – 1 ampoule 3 times a day) or 4 – 6 tablets per day (2 tablets 2 – 3 times a day); Teenagers over 12 years old– take 2 – 4 ampoules per day (1 ampoule 2-3 times a day or 2 ampoules 2 times a day) or 6 – 8 tablets per day (2 tablets 3 times a day or 4 tablets 2 times a day). Clarifying the dosage not only by age, but also by body weight is very important. The fact is that even if the child is one year old, but his weight is less than 10 kg, then he cannot be given Magne B6 solution. Also, you should not give pills to a child if he is 6 years old but weighs less than 20 years. In this case, a six-year-old child is given a solution in dosages for 1 to 6 years.

For children 1–6 years old, it is recommended to calculate the dosage individually based on body weight. For example, a child’s weight is 15 kg, which means he can be given a solution in a dosage of 10 * 15 = 150 mg, or 30 * 15 = 450 mg per day (calculation is based on the amount of magnesium). Since one full ampoule contains 100 mg of magnesium, 150 mg and 450 mg correspond to 1.5 or 4.5 ampoules. When the calculation results in an incomplete number of ampoules, it is rounded to whole numbers. That is, in our example, 1.5 ampoules are rounded to 2, and 4.5 - to 4, since the maximum permissible dosage for a child 1 – 6 years old is 4 ampoules.

Magne B6 forte can be given to children over 6 years old, provided that their body weight is more than 20 kg. Dosage of Magne B6 forte for children of various ages next:

Teenagers over 12 years old– take 3 – 4 tablets per day (1 tablet 3 times a day or 2 tablets 2 times a day); Children 6 – 12 years old– take 2 – 4 tablets per day (1 tablet 2-3 times a day or 2 tablets 2 times a day). The indicated daily amount of Magne B6 and Magne B6 forte should be divided into 2 - 3 doses and drunk with meals. It is optimal to give the child all 2 - 3 doses of the drug before 17.00. The solution from the ampoules for administration is first diluted in half a glass of still water, and the tablets are washed down with a glass of water.

The course of use of Magne B6 for children without confirmed magnesium deficiency is 2–3 weeks. For children with identified and laboratory-confirmed magnesium deficiency, the drug is given until the level of the mineral in the blood rises to normal values.

Side effects

Magne B6 is usually well tolerated, but in rare cases it can cause the following side effects: Allergic reactions; Nausea; Vomiting; Flatulence; Diarrhea; Constipation; Abdominal pain; Paresthesia - a feeling of crawling, numbness, etc. (occur only when long-term use in high dosages); Peripheral neuropathy (occurs only with long-term use in high dosages).

Contraindications for use

Magne B6 tablets and solution are contraindicated for use in humans following states or diseases:
Renal failure, in which creatinine clearance (CC) is less than 30 ml/min; Age under 6 years (only for Magne B6 and Magne B6 forte tablets); Age under 1 year (for oral solution); Fructose intolerance (for tablets Magne B6 and Magne B6 forte); Sucrase-isomaltase deficiency (for Magne B6 and Magne B6 forte tablets); Glucose-galactose malabsorption syndrome (for Magne B6 and Magne B6 forte tablets); Taking Levodopa; Phenylketonuria; Increased individual sensitivity to the components of the drug .

Analogs

Magne B6 has two types of analogues - these are synonyms and, in fact, analogues. Synonyms include medications that contain the same active substances as Magne B6. Analogues include drugs that have a similar spectrum of therapeutic action, but contain other active substances.

On the Russian pharmaceutical market Magne B6 has only three synonymous drugs:

Magnelis B6; Magvit; Magnesium plus B6. On the Ukrainian pharmaceutical market In addition to those indicated, there are two more synonymous drugs - Magnicum and Magnelact. Previously, Magnelact was also sold in Russia, but its registration has now expired.

The following drugs are analogues of Magne B6:

Additiva magnesium effervescent tablets; Vitrum Mag chewable tablets; Magne Positive tablets; Magne Express granules for resorption; Magnerot tablets; Magnesium-Diasporal 300 granules for the preparation of solution for oral administration; Magnesium plus tablets.

Cheap analogues of Magne B6

The following drugs are cheaper synonyms compared to Magne B6:

Magnelis B6 – 250 – 370 rubles for 90 tablets; Magnesium plus B6 – 320 – 400 rubles for 50 tablets. The cost of Magnelis B6 and Magnesium plus B6 is almost two or more times lower than that of Magne B6.

The only cheaper analogue of Magne B6 is Vitrum Mag - 270 - 330 rubles for 30 tablets.

Magne B6 is one of the most popular vitamin complexes modernity. Its main category of consumers are women and children, in whom a lack of magnesium in the body provokes various abnormalities in the functioning of the nervous system.

A patient who came to see a neurologist If you complain of irritability and insomnia, they will recommend drinking Magne B6. Pregnant women with uterine tone and problems with pregnancy will be prescribed the same.

A pediatrician, having listened to parents' complaints about increased fatigue and excessive psycho-emotional excitability in a schoolchild, will prescribe a course of the same drug. By the way, an attentive doctor will additionally ask whether the son or daughter boasts of the ability to bend his fingers in reverse side, and how often does mom panic over trifles? And if such a superpower, and scientifically hypermobility of the joints, occurs, and the mother actually periodically experiences panic attacks, then one can suspect insufficiency (dysplasia) in both of them. connective tissue. Then certainly magnesium and pyridoxine “in one bottle” will become a family pharmaceutical product. And doubly necessary if correction of excess weight is also required.

The therapeutic effect of Magne B6 has been confirmed by multiple clinical studies, and practical results are encouraging ordinary people"from the street". What does it contain that is so useful, why is its help considered real by most consumers? Consisting of two active substances- And . Their synergy leads to rapid positive changes in people’s condition.

Mg is a metal of life, extremely necessary for muscle nerve tissue and proper metabolic metabolism. With its deficiency, you can’t even dream of healthy nerves, a liver and a slim figure. and resistance to obesity directly depend on the magnesium status of the body. But the absorption of this microelement without its partner pyrodoxin would be incomplete (it is quickly eliminated) and the effect would not be as effective.

B6 is a vitamin from the neurological group B, ensuring the transportation and absorption (fixation) of its microelement-companion by the cells, itself is the most important participant in the metabolism of fats, carbohydrates and proteins. It saves from atherosclerosis, reducing homocysteine, from diabetes, supporting insulin production.

The original French product Magne B6 from Sanofi is available in three forms, the equivalents of Mg in which are organic salts - lactate dihydrate, citrate, magnesium pidolate.

Name and form release	Current substance by Mg, mg	B6, mg	Peculiarities	Daily dosage	Price
Magne B6, table 50 pcs.	lactate dihydrate, 470 mg (48 mg Mg)	5	lactic acid salt has good digestibility.	4-6 pcs. children over 6 years old (weighing ≥ 20 kg); 6-8 pcs. adults.	490-618
Magne B6, 10 ampoules of 10 ml.	pidolate, 936 mg; lactate, 186 mg.	10	the solution is recommended for prompt elimination Mg deficiency (pidolate increases digestibility); has a cherry-caramel taste, prescribed to overweight children from 1 year; contains no sucrose.	1-4 amp. children weighing ≥ 10 kg (from 1 year); 3-4 amp. adults.	475
Magne B6 forte, Table 30 pcs.	citrate, 618, 43 mg (100 mg Mg)	10	magnesium salt and citric acid are prescribed for obese adolescents (it breaks down fats better and reduces hunger); highest digestibility, the safest and most effective form of Mg, citrate is a participant in cellular energy cycles, completely processed; the risk of stone formation in the kidneys is reduced.	2-3 pcs. children weighing ≥ 20 kg (from 6 years); 3-4 pcs. adults.	584-730

The treatment regimen is the same: the daily volume is divided into 2-3 doses and combined with food. The ampoules are dissolved in 100 g of water, and the tablets are washed down generously with at least 1 glass.

For what problems is it prescribed?

Official indications for treatment:

magnesium deficiency (preferably diagnosed);
abnormal nervousness, irritability, mild sleep disorders;
tachycardia, gastrointestinal spasms, increased fatigue;
pain, cramps, spasms, tingling in the muscles.

For whom the risk of harm is higher than the potential benefit

Contraindications:

allergic reaction to components;
renal failure; if the kidneys cannot cope with the excretion of magnesium, dangerous hypermagnesemia may develop with a simultaneous decrease in calcium and potassium levels;
violation amino acid metabolism(phenylketonuria);
congenital inability to digest sucrose and isomaltose. This item is applicable for tablet forms; the solution in ampoules does not contain sucrose;
fructose intolerance;
those taking Levodopa (for parkinsonism);
children weighing less than 20 kg for medicine in tablets and less than 10 kg for solution;
During treatment with tetracyclines, magnesium therapy is canceled.

Women who are breastfeeding should avoid taking Mg-containing products.

The drug is prescribed by an obstetrician-gynecologist according to indications, one of which is preeclampsia (swelling, fatigue, increased blood pressure). It is important to prevent seizures.

If not Magne B6, then what instead?

The drug is available over-the-counter, and it is easy to decide on your own whether you need to purchase it. Do you often panic and like to beat yourself up? Is yelling becoming a habit? Do you relieve stress with delicious food? And during PMS you just want to vomit and throw? You don’t even have to contact a neurologist, but go to the pharmacy and look on the shelves for a white and blue box of Magne B6 or its cheaper analogues. They are usually located nearby. They contain the same things - magnesium and pyridoxine B6.

The branded option is good for everyone, but worthless for one - the cost. For low-income Russians it is too high. Not everyone is ready to shell out five bucks for one box of product, even a very good one, but designed for only ten days of use. After all, the treatment course lasts a month, and this is three packages.

What similar things does the pharmacological market offer us? Not much, but there is something.

Magnelis B6 - our domestic answer to the French

It is believed that this is a direct analogue, manufactured in Ufa, at the plant of the largest and most influential company, Pharmstandard OJSC. And it is also a medicine. Exact copy The basic format of Magne B6 contains: 470 mg of magnesium lactate and 5 mg of pyridoxine.

In turn, the “Forte” modification of Ufa manufacturers repeats a similar version of the brand from Sanofi - magnesium citrate 618, 43 mg, B6 - 10 mg. The active components are twins, well, or almost identical, if you don’t dig into how lactate dehydrate (anhydrous) differs from just lactate. And the forming substances are similar in many ways, but not in everything. Let's consider the main groups and calculate the total weight of their components (core + shell):

Add. Components	Magne B6, mg	mg	Magne B6 forte, mg	Magnelis B6 forte, mg	Magne B6 solution mg
Sweeteners	sucrose 330.569 mg	sucrose 194.1 mg	lactose 50.57 mg	lactose 92,2-96,05 (as part of ludipress)	sodium saccharinate, 15 mg
Gum stabilizer Magnesium stearate	23,615 6.7	29 6,8	— 1,0	— 1,0	—
Binding	carbomer 934 10 mg	Kollidon SR 34 mg	macrogol 6000 highest purification, 121.17 mg	Ludipress contains: povidone, collidone, croslovidone in variations - 5.16-9.0 mg macrogol 6000- 69.36 mg
Leavening agents: talc titanium dioxide kaolin	42,7 1,416 40,0	24,8 — 95,0	footprints 4,75 —	2,0 6,0 —	—
Shell	repetition of the specified	gelatin 0.9 mg beeswax 0.4 mg	hypromellose 14.08 mg (the rest are calculated above)	hypromellose 10 mg hyproloz 1 mg macrogol 3350 - 1 mg	—

There is an opinion that generics of original drugs suffer from a worse composition of the fillers that form the tablet. If you pay attention to Magnelis B6, it is not inferior in this regard to Magna B6, and even looks more attractive in some ways. So, it contains less sucrose (why do we need excess sugar?!), and excess talc is not welcome either in pharmaceuticals or cosmetics. Here you can find fault with Kollidon SR, which contains sodium lauryl sulfate. Anyone who is afraid of its good permeability may be wary if order with the excretory system is not a big problem.

In the “forte” version, the auxiliary formula changes significantly and for the better. The composition includes:

Macrogol- without being absorbed itself, it controls the absorption of magnesium by the intestine.
Lactose- a disaccharide, has multiple functions: promotes the proliferation of lactobifidobacteria, which is important for dysbacteriosis, helps the absorption of and, stimulates the nervous system of an adult and has a positive effect on the development of the children's central nervous system. It is also very useful for the heart and blood vessels.
Film coating of tablets using hypromellose- the key to controlled release and bioavailability of essential substances.

It's easy to see that Magne B6 forte is a purified version and less “sugary”.

Prices Russian substitute can't help but please.

There is no replacement for Magne B6 solution. The result is a flavored mixture that is convenient for adults and tasty for children, based on a universal sweetener that has no contraindications. With the presence of sodium disulfite as a preservative, it became possible to increase the shelf life of the drug to 3 years versus 2 for tablet versions.

Magnikum - Kyiv analogue of the French brand

Another twin of Magne B6, or rather Magnelisa B6, only cheaper. Ukrainian pharmacists repeated the composition of the active ingredients of the original, taking some “liberties” in the selection of auxiliary components.

Among the undesirable ones is the use of the same Na lauryl sulfate. Everything else is fine. Interestingly, the manufacturer recommends a much lower daily dosage for the same medicinal proportions: 2 tablets. x1 time or 1 table. x2 times a day.

The price in Russia for a package of 50 tablets is 460 rubles. But not every pharmacy chain purchases the drug.

Children are allowed to take Magnicum and Magnelis from the age of 12.

Magne Express - dietary supplement from Austria from HERMES Pharma

Magnesium B6 dietary supplement - solution from Evalar

Magnesium from tablet preparations based on its organic salts is absorbed to the maximum extent possible.60%. And this percentage gives citrate. Pidolate, lactate, and aspartate provide less absorption, and the decrease occurs in the same sequence. Nerves, as Evalar promises, may become stronger after taking a course of this dietary supplement, but people with other diseases need to be on their guard.

The tablet core contains molasses. This inert substance is widely used in food and pharmaceutical production. But it has a high glycemic index. This supplement is prohibited for diabetics.

Hydroxypropyl cellulose, otherwise known as E463, is an unsafe additive; it is not officially allowed in the Russian Federation (it is allowed in the EU). It is believed to be cholesterol-raising and cancer-forming.

For people with gastrointestinal diseases, consumption of products with E463 is contraindicated.

Polyethylene glycol (E 1521) is approved for use in both the EU and the Russian Federation. But it is necessary to take into account its possible toxicity in case of insufficient purification.

If the same polyethylene glycol is found in Magne B6 and Magnelis B6 of the highest purity (macrogol 6000), then the manufacturer Evalar does not provide such information about its component.

The instructions indicate that the supplement is not contraindicated for pregnant women. But whether or not the expectant mother should drink it is up to her to decide.

American dietary supplement Ultra-Mag - healthy food for muscles and nerve cells

A balanced complex product represented by magnesium salts: citrate, malate, succinate, taurate, glycinate. Magnesium in two tablets contains 400 mg ( daily norm), and vitamin B6 - 50 mg.

The dose of pyridoxine is not small at a norm of 2 mg, but within acceptable therapeutic limits (100 mg). Among the forming substances are already familiar acacia gum, magnesium stearate, silicon dioxide, as well as stearic acid and cellulose gum. 1-2 tablets per day are taken with food. Food supplement no sugar, dyes, gluten, no flavorings.

The price on websites for 120 tablets is 658 rubles (on promotion) - 1390 rubles.