Honey preparation calcium chloride contraindications for. Calcium chloride from allergies: indications and contraindications

Improper functioning of organs and systems, acute immune reactions, and allergic diseases often develop against the background of a lack of certain substances. Calcium chloride replenishes the deficiency of a useful component, enhances resistance to foreign agents, and reduces sensitization of the body.

How does calcium chloride work for allergies? How to use the drug in the form of a solution? What are the pros and cons of calcium chloride? The answers are in the article.

Composition and release form

A drug with a general strengthening, anti-allergic, anti-inflammatory effect is a clear liquid for intravenous or oral administration. The medicinal solution is in ampoules, the concentration is 10%, the volume of the drug in each container is 5 or 10 ml. The excipient is water for injection. The carton contains 10 ampoules.

Action

If the rules of use are followed, the medicine gives a noticeable therapeutic effect:

metabolic processes are normalized;
reduces the risk of seizures against the background of calcium deficiency;
the permeability of cells and the vascular wall decreases;
the patient recovers more quickly after a serious illness;
a moderate diuretic effect is manifested;
the sensitivity of the body to the influence of stimuli decreases;
inflammatory processes develop less frequently;
it is more difficult for infectious agents to act in the body;
The adrenal glands secrete more epinephrines.

In the complex treatment of allergic diseases, the positive effect of the drug is manifested:

rashes of a different nature disappear;
tissue swelling decreases;
increases the flow of adrenaline into the blood, stimulates work nervous system;
the condition is normalized with allergies of varying severity.

About half of the volume of the active substance binds to the blood plasma. Residues of the drug are excreted through the intestines (80%) and in the urine (less than 20%).

Calcium chloride: indications for use

The drug is recommended as part of complex therapy for many allergic diseases. A prerequisite is a combination of calcium chloride and modern antihistamines: , . “Hot injections” and ingestion of the solution have a positive effect on the condition of allergy sufferers.

Important! An effective composition for strengthening the body can only be prescribed by a doctor: self-administration and lack of special knowledge provoke complications. The use of calcium chloride as the main component to eliminate signs of allergies is prohibited.

Indications for prescribing a medicinal solution:

and other medicines of various kinds;
allergic dermatoses;
of a different nature;
acute response to the administration of serum proteins.

calcium deficiency in food;
hypocalcemia;
osteomalacia;
bleeding of a different nature;
conditions in which the level of Ca drops sharply;
nephritis;
hepatitis;
breastfeeding period (on the recommendation of a gynecologist and therapist);
toxic effects of oxalic and fluoric acids, magnesium salts;
pulmonary tuberculosis;
period of menopause.

Contraindications

The drug is not suitable for patients with the following diseases:

atherosclerosis (severe stage);
urolithiasis disease;
thrombosis;
pregnancy;
excessive sensitivity to the active substance;
high concentration of calcium ions in the blood;
renal failure (chronic form);
sarcoidosis

You should not take calcium chloride if cardiac glycosides are included in the list of therapeutic agents. The result of a combination of two types of drugs is a cardiotoxic effect.

The main types of intake during therapy:

intravenously (stream or drip);
oral intake;
during electrophoresis.

Children are allowed only one method of use - taking the medicinal solution orally. All forms are suitable for adults: the choice of method is made by the attending physician.

intravenous administration. The procedure is popularly known as a “hot injection” of calcium chloride. To dilute the composition, sodium chloride and glucose solution (dextrose) are used. The injections are done by a health worker. Features of the administration of calcium chloride: it is important to inject the medicine into a vein slowly, no more than 1.5 ml per minute. For one procedure, the volume of the drug should not exceed 3 ampoules. Violating the rules has a negative effect on the heart, even to the point of stopping it. After the procedure, the patient is under the supervision of a specialist for 15-20 minutes, the “lying” position is mandatory. You should not get up suddenly after the procedure: arrhythmia, fainting, or a sharp drop in blood pressure are possible;
oral intake. For internal use, the doctor prescribes a solution of 5 or 10% concentration. Take the drug only after meals. An important point is compliance with the dosage: children - 0.3 ml of the drug per 1 kg of body weight, maximum 10 ml per day. The daily dosage for adults is no more than 15 ml, for children under 12 months - no more than 0.5 ml per day. The optimal frequency of taking calcium chloride orally is two to three times a day.

On a note! Did you know that calcium chloride is actively used in cosmetology clinics and for effective cleansing of facial skin at home? Delicate peeling is carried out using baby soap, medicinal solution and cotton pads. The effect of the procedure is the removal of blackheads, reduction of oily skin, narrowing of pores, prevention of inflammatory processes in the upper layers of the epidermis during the period of hormonal changes in the body.

Side effects

Patients tolerate well the intake and intravenous administration of calcium chloride. A prerequisite for minimizing the risk of negative reactions is compliance with the rules of use.

Discomfort during procedures is expressed in the following signs:

redness of the skin of the face, a feeling of heat;
low heart rate;
too fast a rate of drug administration causes ventricular fibrillation;
oral intake of calcium chloride sometimes causes heartburn and painful sensations in the epigastrium;
some patients feel an unpleasant tingling along the vein into which the active solution is injected.

Drug interactions

Useful information about the effect of calcium chloride:

combination with digoxin, tetracycline antibiotics, and iron supplements reduces the absorption of these drugs. The optimal interval between taking a solution of calcium chloride and the indicated items is at least two hours;
simultaneous use with thiazide diuretics provokes hypercalcemia and reduces the level of bioavailability of phenytoin.

Calcium chloride is an inexpensive drug for the complex treatment of allergic reactions. Depending on the volume of the ampoule (5 or 10 ml), package No. 10 costs from 30 to 105 rubles. The price of calcium chloride varies significantly depending on the manufacturer.

Find out the instructions for use for children and adults.

For a list and characteristics of medications for urticaria in adults, see the page.

Go to the address and read about the symptoms and treatment of allergic vasculitis.

Additional Information

During treatment with calcium chloride, the attending physician must inform the patient about the effect of the drug on the body. It is forbidden to inject the medicinal solution yourself: violation of the rules, exceeding the concentration of the active component (5% or more), and the rate of administration often causes tissue necrosis.

On a note:

It is prohibited to administer calcium chloride subcutaneously or intramuscularly: possible severe irritation, tissue death;
with intravenous administration, the patient feels heat in the mouth, then the heat spreads to other parts of the body;
when injected into a vein, painful sensations along the vessels and redness of the tissues are possible;
The drug is sold in pharmacies without a prescription, but doctors strongly advise against taking the medicinal solution yourself. Failure to comply with the dosage often provokes severe side effects; a violation of the volume or concentration of the drug is dangerous for patients, especially children;
When fever or discomfort appears, many people panic, get up from the couch, and take fever pills. Improper actions often harm the cardiovascular system. Monitoring by a healthcare professional reduces the risk of side effects: a specialist will tell the patient how to behave after a “hot injection” or oral administration, what sensations should not be scary, and what phenomena will require urgent medical attention.

The patient must observe the temperature regime for storing the medicinal solution: from +15 to 25 degrees. It is prohibited to freeze containers with the drug: the composition loses its active properties. Be sure to keep the drug ampoules away from sunlight and heating appliances. The solution for oral and intravenous administration is suitable for five years.

Analogs

Other names are suitable for replenishing Ca reserves. Many medications are more expensive than calcium chloride. The selection of the product and the optimal method of application is carried out by the doctor.

Ca preparations with similar effects:

Latoxyl.
Glyukosil.
Sodium chloride.
Reamberin.
Xylate.
Magnesium sulfate.

Formula: CaCl2, chemical name: calcium chloride.
Pharmacological group: metabolism/macro- and microelements.
Pharmachologic effect: anti-inflammatory, antiallergic, hemostatic, reducing capillary permeability, detoxification.

Pharmacological properties

Calcium chloride compensates for the lack of calcium ions, which are necessary for the contraction of smooth and skeletal muscles, transmission of nerve impulses, heart function, blood clotting, and bone tissue formation. Calcium reduces the permeability of cell membranes and vessel walls, prevents the development of inflammation, enhances phagocytosis and increases the body's resistance to infections. When administered intravenously, it stimulates the autonomic nervous system (its sympathetic department), increases the secretion of adrenaline by the adrenal glands, and has a moderate diuretic effect. When calcium chloride interacts with fluoric and oxalic acids, magnesium salts, insoluble compounds are formed, which allows the use of calcium chloride solution as an antidote for poisoning with these substances.

Indications

Hypocalcemia; increased need for calcium (pregnancy, breastfeeding, increased body growth); calcium metabolism disorders, including in the postmenopausal period; insufficient intake of calcium from food; increased excretion of calcium (secondary hypocalcemia, including during prolonged use of anticonvulsants, some diuretics or glucocorticoids, chronic diarrhea); bleeding of various origins and localization; allergic reactions and diseases, including serum sickness, urticaria, Quincke's edema, itching, bronchial asthma; exudative and inflammatory processes, including pneumonia, adnexitis, pleurisy, endometritis, increased vascular permeability (radiation sickness, hemorrhagic vasculitis), dystrophic alimentary edema; hypocalcemia; hypoparathyroidism; spasmophilia; tetany; lead colic; hyperkalemic form of paroxysmal myoplegia; rickets and osteomalacia; pulmonary tuberculosis; hepatitis (toxic, parenchymal); eclampsia; nephritis; poisoning with fluoric and oxalic acids, magnesium salts; psoriasis; eczema; weakness of labor.

Method of use of calcium chloride and dose

Intravenously, slowly (6 drops/min) - before administration, 5–10 ml of a 10% solution is diluted in 100–200 ml of a 5% dextrose solution or isotonic sodium chloride solution. Orally, after meals, 2-3 times a day in the form of a 5-10% solution: adults - 10-15 ml per dose, children - 5-10 ml.
If you miss the next dose of calcium chloride, take it as you remember, and take the next dose after the set time from the last use. Calcium chloride should not be administered intramuscularly or subcutaneously, as tissue necrosis may develop due to its strong irritant effect. When calcium chloride is administered intravenously, a sensation of heat first appears in the oral cavity, and then throughout the body (this effect was previously used to determine the speed of blood flow - the time between the moment of intravenous administration of the drug and the appearance of a sensation of heat was recorded).

Contraindications for use

Hypersensitivity, atherosclerosis, hypercalcemia, tendency to thrombosis.

Restrictions on use

No data.

Use during pregnancy and breastfeeding

During pregnancy and breastfeeding, calcium chloride can be used, but only as indicated when prescribed by a doctor.

Side effects of calcium chloride

When taken orally - heartburn, epigastric pain, nausea, gastritis, vomiting. When calcium chloride is administered intravenously - a feeling of heat, bradycardia, facial flushing; with rapid intravenous administration - ventricular fibrillation; local reactions when used intravenously - hyperemia and pain along the vein.

Interaction of calcium chloride with other substances

Calcium chloride is incompatible with salts of silver, lead, monovalent mercury due to the formation of insoluble chlorides of these metals, as well as with sodium barbital due to the formation of slightly soluble calcium salt of barbital. Calcium chloride, when used together, reduces the effects of calcium channel blockers. Under the influence of cholestyramine, the absorption of calcium chloride in the gastrointestinal tract is reduced. When used together with quinidine, it is possible to increase the toxicity of quinidine and slow down intraventricular conduction. When treating with cardiac glycosides, parenteral use of calcium chloride is not recommended, due to the increased cardiotoxic effects of glycosides.

Name:

Calcium chloride (Calcii chloridum)

Pharmacological
action:

Calcium - macronutrient, involved in the formation of bone tissue, the process of blood clotting, is necessary to maintain stable cardiac activity and the processes of transmission of nerve impulses.
Improves muscle contraction in muscular dystrophy, myasthenia gravis, and reduces vascular permeability.
When administered intravenously, calcium causes stimulation of the sympathetic nervous system and increased secretion of adrenaline by the adrenal glands; has a moderate diuretic effect.
When a calcium chloride solution interacts with magnesium salts, oxalic and fluoric acids, insoluble compounds are formed, which makes it possible to use a calcium chloride solution as an antidote.

Indications for
application:

With insufficient function of the parathyroid glands, accompanied by tetany or spasmophilia (a disease in children associated with a decrease in the content of calcium ions in the blood and alkalinization of the blood);
- with increased release of calcium from the body, which can occur during prolonged immobilization of patients;
- for allergic diseases (serum sickness, urticaria, angioedema, hay fever, etc.) and allergic complications associated with taking medications. The mechanism of the antiallergic effect is unclear; however, it should be noted that intravenous administration of calcium salts causes stimulation of the sympathetic nervous system and increased secretion of adrenaline by the adrenal glands;
- as a means of reducing vascular permeability in hemorrhagic vasculitis (hemorrhage due to inflammation of the walls of blood vessels), radiation sickness, inflammatory and exudative processes (release of protein-rich fluid from small vessels of tissue) - pneumonia (pneumonia), pleurisy (inflammation of the membrane, covering the lungs and lining the walls of the chest cavity), adnexitis (inflammation of the uterine appendages), endometritis (inflammation of the inner surface of the uterus), etc.;
- for skin diseases (itching, eczema, psoriasis, etc.). For parenchymal hepatitis (inflammation of liver tissue), toxic liver damage (damage to the liver by harmful substances), nephritis (inflammation of the kidney), eclampsia (severe form of late toxicosis of pregnancy), hyperkalemic form of paroxysmal myoplegia (paroxysmal / periodically occurring / paralysis occurring with an increase in the content of potassium in the blood);
- as a hemostatic agent for pulmonary, gastrointestinal, nasal, and uterine bleeding; in surgical practice, it is sometimes administered before surgery to increase blood clotting. However, there is no sufficiently reliable data on the hemostatic (hemostatic) effect of calcium salts introduced into the body from the outside; calcium ions are necessary for blood clotting, but the amount of calcium usually contained in the blood plasma exceeds the amount required to convert prothrombin into thrombin (one of the blood clotting factors);
- as an antidote for poisoning with magnesium salts (see magnesium sulfate), oxalic acid and its soluble salts, as well as soluble salts of fluoric acid (when interacting with calcium chloride, non-dissociating / non-disintegrating / and non-toxic oxalate and calcium fluoride are formed);
- the drug is also used in combination with other methods and means to stimulate labor.
When taken orally (8-10 g) it has a diuretic (diuretic) effect; According to the mechanism of action, it belongs to acid-forming diuretics.

Mode of application:

Prescribe calcium chloride inside, intravenous drip(slowly), intravenous stream(very slowly!) and also administered by electrophoresis(percutaneous administration of medicinal substances through electric current).
Taken orally after meals in the form of a 5-10% solution 2-3 times a day.
Adults are prescribed 10-15 ml per dose (dessert or tablespoon of solution); children - 5-10 ml (teaspoon or dessert spoon).
6 drops per minute are injected into a vein, diluting before administration with 5-10 ml of a 10% solution in 100-200 ml of isotonic sodium chloride solution or 5% glucose solution.
5 ml of a 10% solution is injected intravenously slowly (over 3-5 minutes). For the treatment of allergic diseases, the combined use of calcium chloride and antihistamines is recommended.

Side effects:

When taking calcium chloride orally, pain in the epigastric region and heartburn are possible;
- when administered into a vein - bradycardia (decreased heart rate);
- with rapid administration, ventricular fibrillation of the heart (chaotic contractions of the heart muscle) may occur;
- with intravenous administration of calcium chloride, a feeling of heat appears first in the oral cavity, and then throughout the body. This feature of the drug was previously used to determine the speed of blood flow; The time between the moment of its introduction into the vein and the appearance of a sensation of heat was determined.

Contraindications:

Calcium chloride solutions cannot be administered subcutaneously or intramuscularly, as they cause severe irritation and necrosis (death) of tissue.
Calcium chloride is contraindicated in cases of a tendency to thrombosis (blockage of a vessel with a blood clot), advanced atherosclerosis, or increased calcium levels in the blood.

Interaction
other medicinal
by other means:

Calcium chloride is incompatible with salts of lead, silver, monovalent mercury due to the formation of insoluble chlorides of heavy metals and with sodium barbital, because in this case, a slightly soluble calcium salt of barbital is formed.
Calcium chloride, when used simultaneously, reduces the effect of calcium channel blockers. Under the influence of cholestyramine, calcium absorption from the gastrointestinal tract is reduced.
When used simultaneously with quinidine, intraventricular conduction may slow down and the toxicity of quinidine may increase.
During treatment with cardiac glycosides, parenteral use of calcium chloride is not recommended due to increased cardiotoxic effects.

We are all accustomed to the fact that chemical synthetic food additives only cause harm to the human body. However, this is not the case. There are artificially derived substances that bring much more benefit than potential danger. One of these safe substances is the stabilizer and emulsifier E509, most popularly known as calcium chloride.

The safety of such a food additive has been proven through many scientific studies and experiments, thanks to which calcium chloride has received official permission for use in various industries, including the food industry.

Physical and chemical properties of the product

Calcium chloride has other names: calcium chloride, calcium chloride nitrate, E509. Molecular formula of the substance: CaCl 2.

This food additive is presented in the form of crystal-shaped granules, often white, less often completely transparent.
The substance has high moisture absorption, dissolves well in alcoholic liquids and. Resistant to high temperatures. The melting point of calcium chloride is seven hundred and seventy-two degrees Celsius, and it boils at a temperature of 1935 degrees Celsius. At the same time, an aqueous solution of the substance crystallizes at temperatures below twenty degrees Celsius.

This food additive is obtained during the production of soda, namely through the recovery of ammonia.

Use of the substance in the food industry

On the territory of the Russian Federation, the use of this substance is not prohibited, but is strictly controlled by law. The European Union also considers calcium chloride a fairly safe product and it is legally used in the medical and food industries.

As a food additive, calcium chloride is included in a wide variety of food products to stabilize some of their properties, and also as an emulsifier and preservative. Most often it can be found in dairy and fermented milk products, especially in pasteurized ones. But it is also found in various types of cheeses.

This substance is used in the food industry for the following processes:

During pasteurization, adding calcium chloride to them significantly reduces the acidity, which facilitates the process of making oil.
It is indispensable as a thickening component in the production of milk powder. The fact is that calcium ions help better adhesion to each other. This substance allows you to normalize the coagulation process of dairy products during pasteurization and improves the formation of the curd. Adding it to milk increases its final yield and leads to a significant improvement in quality.
An additive marked E509 acts as a stabilizer in the production of chocolate, preventing it from hardening.
When making cottage cheese, calcium chloride helps milk coagulate better.
When making marmalade, calcium chloride also acts as a stabilizer.
This substance prevents the softening of vegetables and fruits during the preservation process, and also normalizes the taste, bringing it to the desired salting level.
In the production of beer and soft drinks, this product is used to reduce water hardness and improve its performance, as well as to regulate acidity.

Application in other areas

Due to its beneficial qualities, calcium chloride is widely used in various areas of life. This is a popular product in the medical and pharmaceutical industries; it is often included in various medications aimed at improving blood clotting, as well as antihistamines.

Food emulsifier E509 is used for the following processes:

production of latex goods and rubber products;
for the production of lactic acid;
in the production of glue;
for the production of rubber products;
when laying asphalt, improving its adhesion;
used as an anti-dust and de-icing agent;
in preparation for gas transportation;
in the production of calcium metal;
when the dew point decreases and gas drying occurs at gas distribution stations and autogas filling compressor units.

Beneficial and harmful properties of the E509 additive

No matter how safe a substance is, it must be consumed in acceptable dosages. The daily norm for an adult is 350 mg of calcium chloride. And this dose is considered absolutely harmless and safe.

Negative and unpleasant consequences can arise when the permissible dosages are increased. Consumption of this emulsifier in large quantities causes irritation of the digestive organs; in the most serious situations, this can lead to the development of gastric ulcers.

However, the beneficial properties of this substance significantly exceed the possible harm. These include:

assistance in the formation of bone tissue;
compensation of calcium in the human body, which has a positive effect on the nervous system and contraction of muscle tissue;
regulation of blood clotting;
helps to increase the body's natural defenses and its resistance to various infectious diseases;
positive effect on the heart muscle;
preventing the emergence and development of inflammatory processes.

In addition, calcium chloride is often used for weak labor and liver diseases such as hepatitis or toxic liver damage. It is often used for skin diseases: eczema. Calcium chloride is used for inflammation caused by endometritis, as well as for severe allergic reaction of Quincke's edema.

In pediatric practice, calcium chloride is often used to relieve symptoms of various allergic reactions caused by the consumption of allergenic foods or medications. It is also prescribed to children after vaccinations to relieve unpleasant symptoms.

Instead of conclusions

Calcium chloride is a chemical with such beneficial properties that it is widely used in medicine and in food products. Products prepared using such a food emulsifier are labeled E509. In medicine, calcium chloride has proven itself remarkably as a panacea for various pathologies. In addition, its valuable qualities are successfully applied in other areas of industry. However, it is worth remembering that although this substance is harmless, it must be used in strictly regulated dosages in order to avoid unnecessary unpleasant consequences.

Calcium chloride is a medicine to replenish calcium deficiency in the body.

Release form

Available in the form of a solution for internal use, as well as for intravenous administration.

pharmachologic effect

Calcium chloride compensates for the lack of calcium in the human body. Calcium is an essential element, without which it is impossible to imagine the normal course of almost all processes in the body. It is necessary not only for the formation of bone tissue, but also to ensure the normal functioning of the cardiovascular system, including the functioning of the myocardium and the blood clotting process.

A solution of Calcium chloride can significantly reduce the permeability of cells and vascular walls; it also increases resistance to various infections and prevents the development of inflammatory processes. At the same time, the secretion of epinephrine by the adrenal glands increases. When administered intravenously, this drug is able to stimulate the sympathetic division of the autonomic nervous system and have a moderate diuretic effect.

Indications

Calcium chloride solution in ampoules is prescribed in situations in which there is an increased need for calcium, for example, during pregnancy and lactation, as well as during periods of growth. Also, the use of this drug is effective for bleeding of various origins and localization. It is also used for manifestations of allergic diseases, for example, with urticaria, serum sickness, itching, angioedema and fever.

Often the use of this drug is recommended for bronchial asthma, tetany, alimentary dystrophic edema, rickets, spasmophilia, osteomalacia, lead colic, hypocalcemia, pulmonary tuberculosis, hypoparathyroidism, hemorrhagic vasculitis, radiation sickness, toxic and parenchymal hepatitis, eclampsia, nephritis, paroxysmal myoplegia , psoriasis, eczema, as well as in inflammatory and exudative processes.

Calcium chloride is effective for weakness of labor activity, as well as for poisoning with fluoric and oxalic acids, magnesium salts.

Instructions for use (method and dosage)

In cases where intravenous administration of this drug is recommended, the solution is administered slowly, 6-8 drops per minute. Usually 1-3 ampoules are administered, diluting a 10% solution with 100-200 milliliters of sodium chloride or a 5% dextrose solution.

Calcium chloride solution is taken orally after meals two to three times a day. Most often, a 5 or 10 percent solution is taken. Adults take 10-15 milliliters of the drug, and children are recommended to take no more than 5-10 milliliters.

Very often in cosmetology, calcium chloride is recommended for peeling oily skin. During the peeling procedure, apply to the facial skin twice and wait until completely dry. Then the face is cleaned with soap and water. This removes dead cells from the skin. They roll into balls and are easily removed from the surface of the skin. It is necessary to continue washing as long as lumps remain on the skin.

Contraindications

Calcium chloride in ampoules is not prescribed for severe atherosclerosis, with an increased calcium content in the blood, as well as for patients with a predisposition to the formation of blood clots. The simultaneous use of the drug with phosphates and salicylates, as well as carbonates and sulfates is prohibited.

Drug interactions

During treatment, it must be remembered that this drug significantly reduces the absorption of tetracyclines, digoxin and oral iron supplements. If the drug is taken concomitantly with thiazide diuretics, hypercalcemia may increase, as well as a decrease in the effectiveness of calcitonin and the bioavailability of phenytoin. After peeling with Calcium Chloride, you must refrain from exposure to sunlight for two to three days.

Side effects

When used internally, it can cause pain in the epigastric region, as well as heartburn. When the drug is administered intravenously, a feeling of heat and a decrease in heart rate may occur. If the drug is administered too quickly, irregular contractions of the heart ventricles may occur.