Melissa officinalis herb instructions for use. Melissa: medicinal properties and contraindications for use

"Melissa medicinal herb"is a remedy from the group of herbal remedies that have a sedative effect on the body.

What is the composition and form of release from the drug Melissa officinalis (herb)?

The pharmaceutical industry produces a herbal remedy in the form of crushed raw materials made from grass, which are placed in paper bags, their volume is different: 75, 50 and 30 grams. The active substance is lemon balm medicinal herb. The phytopreparation is packed in a cardboard box, where the date of its release is affixed, and the expiration date is also reflected. Released without a prescription.

In addition, a herbal preparation is produced in powder, which is placed in small filter bags of 1.5 grams, where there is finely ground lemon balm herb. The packages are placed in a cardboard box. Store the herbal remedy in a dark place. The expiration date is indicated on the box, it is three years.

It is important to clean the herbal preparation in a room where there is no high humidity, otherwise the phyto-material may become damp and moldy, which will render it unusable. Accordingly, it is recommended to refuse the subsequent use of such a phytopreparation.

What is the effect of herbal raw materials / powder of Melissa officinalis (herb)?

A decoction prepared on the basis has a mild calming effect on the body, in addition, it has a moderate antispasmodic effect. The leaves of this plant have a lemon smell, they taste a little astringent, bitter-spicy.

Melissa contains some important components, thanks to which this plant has a medicinal effect on the body: essential oil, which includes geraniol, citral, in addition, citronellal, and myrcene.

In addition, in this medicinal plant the following components were found: mucus, resins, bitterness is present, fatty oil, identified ascorbic acid, as well as tannins and some useful organic acids (ursolic, coffee and some others).

What are the indications for use from Melissa officinalis (herb) medication?

The drug "Melissa officinalis herb" instructions for use allow it to be used if a person has increased emotional excitability, it is effective to take this phytopreparation if it is detected, in addition, in case of sleep disturbance, when the patient has a sleep disorder or early awakening often occurs.

What are the contraindications for use from Melissa officinalis (herb)?

Melissa herb is contraindicated for use in the following situations:

Do not prescribe a phytomedicine under 18 years of age;

In addition, a decoction obtained from the herb of this plant is not used for hypersensitivity to any components of this phytopreparation.

What are the uses and dosages of Melissa officinalis (herb) medicine?

To prepare a decoction of lemon balm herb, it is recommended to take a tablespoon of chopped raw materials, after which it is placed in a glass or enameled container, then a glass of boiling water is poured into the container. Then you need to cover the dishes with a lid and place it on a gas stove, where a water bath should be prepared.

In a water bath, the phytopreparation should languish for 15 minutes. After a quarter of an hour, the container is removed from the stove and its contents are cooled for 40-50 minutes, then the broth is filtered through a fine strainer, the raw materials remaining in the container are squeezed out, and the resulting volume is adjusted to 200 milliliters with boiled water.

It should be noted that the phytopreparation enhances the effect of hypnotics and other drugs that depress the central nervous system. Melissa medicinal herb can be used during the lactation period and during pregnancy, but only on the recommendation of a doctor.

In addition, this phytopreparation can be used in filter bags, which is much more convenient, since you do not have to filter the liquid and squeeze out the settled crushed raw materials. To prepare the infusion, one or two bags can be placed in a mug, after which they are poured hot water and insist. Then you can use the herbal remedy for its intended purpose.

What are the side effects of Melissa officinalis (herb)?

Sometimes the use of a phytopreparation, which we continue to talk about on this page www.site, can provoke the development of allergic reactions, which are mainly manifested by dermatological symptoms, for example, swelling, redness and itching may appear on the patient's skin. In this case, you should consult a doctor who will prescribe antihistamine therapy.

Overdose from Melissa officinalis (herb)

In case of an overdose of the phytopreparation, vomiting can be provoked, if after that the patient feels worse, then it is recommended to consult a doctor who will prescribe needed help in the form of symptomatic therapy.

special instructions

In case of intolerance to a herbal remedy based on leaves, it is recommended to replace this medicine.

It is worth noting that with prolonged use of the decoction, especially in large dosages, there may be a decrease in psychomotor reactions in humans, this point is important, as well as in working with mechanisms where increased concentration of attention is needed.

How to replace the drug "Melissa officinalis (herb)", what analogues to use?

Phytopreparation Melison, as well as Melissa tincture.

Conclusion

Be healthy!

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Melissa- a plant used to relax the nervous system, as well as to normalize the functioning of the brain. In addition, lemon balm reduces anxiety and anxiety, especially the effect of using lemon balm is noticeable under stress. Taking medications with lemon balm and lemon balm treatment has a positive effect on improving memory. One study looked at exactly how lemon balm improves mood. It was assumed that the components of the plant, which brought the body into a relaxed state, helped improve the quality of sleep. To date, several studies can be found that indicate that the effectiveness of lemon balm in relieving anxiety leads to the normalization of sleep in people with chronic insomnia. As a result, we can conclude that the improvement of cognitive functions is one of the main features of lemon balm. The described plant really improves memory and speed of memorization. Today, lemon balm is mainly used as a sedative to improve the psycho-emotional state of a person and normalize sleep.

Melissa is one of the components of the natural soothing drug "Nervo-Vit".

Melissa. plant description

Melissa also has other names often used among herbalists: "lemon mint", "lemon balm", etc.

Melissa can be attributed to nootropic drugs, anti-stress sedatives, sleeping pills, as well as drugs used in aromatherapy.

Melissa. Indications for use

Biologically active substances lemon balm can enter the body in the form of natural preparations. One of these drugs is natural remedy"Nervo-Vit", containing lemon balm, motherwort, valerian root and blue cyanosis. Each of the active components has a synergistic effect, thus increasing the effectiveness of the drug "Nervo-Vit". Main indications for the use of melissa and the drug "Nervo-Vit" may be restless sleep and a constant feeling of anxiety.

Melissa. Chemical composition

Melissa belongs to the labial family, is used to eliminate emotional disorders, as well as to improve memory and human sedation. The plant is widely used in European countries, in Russia and in South America. Ancestors used this plant inside in the form of tea or extract.

IN chemical composition lemon balm there are:

• Rosmarinic acid (anti-inflammatory effect)
• caffeic acids (stimulate immune system inhibit the development of cancer).
• Caphtaric acid (immunomodulator)
• Protocatechuic acid (antioxidant)
• salvianolic acid (antioxidant)
• Lithospermic acid ( positive impact for reproductive functions).
• Ursolic acid (anabolic effects)
• Saponins, glycosides, lipids, monoterpenes, sesquiterpenes, alcohols, flavonoids.

Basically, in the composition of lemon balm, you can find caffeic acids and their derivatives, including rosemary to-that. Melissa contains the least amount of triterpenoids and polyphenolic compounds. At the same time, the main flavonoid is luteolin, however, as it was shown later, it does not have significant bioactivity. Total Concentration phenol in large quantities prevails in the aqueous extract. The amount of active phenols in lemon balm is many times greater than in lavender. Thus, the biological activity of lemon balm is more pronounced. The amount of flavonoids in lemon balm reaches almost half of the total composition. This plant also contains moderate amount tannin.

Neurological indications

GABA transmission

Melissa extract shows its activity against GABA ( gamma-aminobutyric acid) is the main inhibitory neurotransmitter of the CNS. In particular, rosmarinic and ursolic acids act on GABA. A decrease in GABA transaminase (an enzyme that inhibits GABA activity) has been found in rodents after ingestion of lemon balm extract at a relative dosage. Based on this, we can conclude that lemon balm has GABA-ergic activity, that is, it contributes to an increase in the level of GABA in the presynapses of the brain. As a result, it enhances the sedative effect of taking lemon balm. The content of lemon balm in the drug "Nervo-Vit" contributes to rapid sedation and sedation in case of psychoemotional disorders, in connection with which, the drug can be taken according to neurological indications.

Relationship with sleep

In a two-week clinical trial in people with unstable nervous systems and sleep disorders, using lemon balm twice a day (in the morning and before going to bed) reduced the incidence of insomnia, which was caused by anxiety. Melissa should generally be taken internally along with valerian to enhance the sedative effect. One study found that combining these two herbs before bed improved sleep by 24% compared to a placebo. This combination has a rather mild effect on the body, which at times reduces the likelihood of side effects. During other studies, it turned out that the combination of valerian and lemon balm has connection with sleep and eliminates sleep disorders in children.

The combination of lemon balm and valerian is intelligently combined in the Nervo-Vit herbal preparation, which also includes other components (blue cyanosis and motherwort) to enhance the sedative effect.

Impact on anxiety

In rodents, moderate dosages of lemon balm containing rosmarinic acid for 2 weeks led to sedative effects. In one study in which animals inhaled steam from boiled lemon balm, anxiolytic effects were observed associated with the effect of steam on serotonin receptors. It has also been found that oral use of lemon balm and inhalation of oil based this plant effective in the treatment of anxiety and post-stress disorders. In human studies, taking lemon balm before a stress test resulted in less response to stress, decreased anxiety, and improved mood. In the course of another experiment, in which moderate dosages of the medicinal plant were used, changes were noted brain activity on the EEG, corresponding to the action of anxiolytic drugs. Melissa renders effect on anxiety , reduces anxiety and normalizes mood with a single dose. Participants in one of the conducted clinical trials, who took moderate dosages of lemon balm in the morning and before going to bed, had anxiolytic effects, in connection with which there was a normalization of appetite and relief anxiety states. Melissa improves sleep, reduces anxiety and anxiety, especially when taken in the morning or some time before bedtime.

To relieve anxiety, it is recommended to take natural preparations "Nervo-Vit", "Motherwort P", "Valerian P" and "St. John's Wort P".

Improving and developing memory

In the course of many studies, experts have found that lemon balm can bind to cholinergic H- and M-receptors. In addition, it has been noted that lemon balm can inhibit acetylcholinesterase when taken in high doses; further experiments failed to detect any effect on acetylcholinesterase. Later it was found that lemon balm extract does not displace nicotine from H-receptors. Melissa can bind to acetylcholine receptors and act as their agonist. In the hippocampus of rats, the growth of nerve cells was observed when taking lemon balm extract; this phenomenon may be due to a decrease in corticosterone levels. In clinical stress tests, taking lemon balm before the study accelerated the search for a solution and response to math problems; doubling the dosage did not improve performance on the intellectual stress test. A one-time intake of lemon balm contributed to improvement and development of memory(in contrast to the placebo group), memory of words, spaces, images and faces was also noted. An additional benefit of taking lemon balm extract is improved response. oral intake lemon balm in large dosages leads to an improvement in mental abilities. The tranquilizing effect of lemon balm affects the speed of learning and the speed of information processing.

Nerve cell protection

In the hippocampus of rodents, whose tissues were subject to hypoxia, moderate dosages of lemon balm contributed to protection of nerve cells from destruction and growth of new neurons. Protective properties active components of lemon balm were also noted when taking alcohol and drugs. Melissa reduces the toxicity of brain cells and has a neuroprotective effect, in addition, one of positive effects lemon balm is its anti-inflammatory effect. In experiments with rodents, a moderate amount of lemon balm extract for 14 days reduced the degree of oxidative stress, the amount of hypoxia-induced factor-1-alpha, as well as the amount of tumor necrosis factor-alpha and interleukin-1-beta. Each of these factors is associated with activation inflammatory processes in organism.

The natural herbal remedy "Memo-Vit" has a neuroprotective effect, which, when taken regularly, protects your nerve cells in the brain.

Analgesic effect

In one study, in rodents that were exposed to physical influence, noted analgesic effect lemon balm, which has been linked to rosmarinic acid. Additional studies are needed to confirm this fact accurately.

Perfectly relieve pain preparations of plant origin "Nervo-Vit", "Valerian P" and "Motherwort P".

Reducing sugar levels

In the course of a study using lemon balm esters for 1.5 months, it turned out that when determining glucose tolerance, essential oils contributed to decrease in sugar levels and insulin in the body. During the trials, there was also a decrease in insulin resistance with oral use of lemon balm.

The effect of viruses on the body

Lemon balm extract led to a decrease in cytopathy when affected by the herpes virus, however, unlike acyclovir, the effect of lemon balm is much weaker and therefore it less effectively reduces the effect of viruses on the body.

To enhance immune functions and protect against viruses, it is recommended to take natural herbal remedies: Apitonus P, Echinacea P, Sage P, Licorice P.

Influence on oxidative processes

The antioxidant effects of lemon balm are noted with oral use of lemon balm. This was established by determining the degree of lipid peroxidation in the brain. The antioxidant effect of lemon balm, as well as its influence on oxidative processes more pronounced than chamomile, but slightly inferior to quercetin. In mice, lemon balm, taken for 14 days, protects cell DNA from damage when exposed to methyl ester. Lower dosages showed the same efficiency in relation to the processes of reducing toxicity in cells. In the course of clinical trials, against the background of the influence of the active substances of lemon balm on radiologists who were regularly exposed to gamma radiation, experts found that frequent use lemon balm, which is contained in the preparation "Nervo-Vit", within 1 month reduces oxidative stress in cell nuclei. The antioxidant effect of this herbal remedy was clinically confirmed with daily intake of lemon balm.

To protect against oxidative stress, natural preparations "Apitonus P" and "Dihydroquercetin Plus" have long been used to protect against the action of free radicals.

Effect on cancer cells

In oncocytes (cancer cells) of the large intestine, destructive changes against the background of the use of an aqueous extract of lemon balm; alcohol extract reduced the proliferation of oncocytes and slowed down carcinogenesis. Thus, the destructive Influence at cancer cells when using melissa.

The antitumor effect is noted in the natural antioxidant - dihydroquercetin, which is present in the composition natural preparations"Dihydroquercetin Plus" and "Apitonus P". In addition, the anti-cancer properties of drone brood were discovered, which is included in the composition of such preparations as: Leveton Forte, Eromax, Memo-Vit, Osteomed, Osteo-Vit, Osteomed Forte, Eromax", "Dandelion P", each of which has a lot of useful and medicinal properties.

Melissa and valerian are often used simultaneously to normalize sleep, since lemon balm promotes inhibition of GABA transaminase enzymes (slows down the destruction of GABA), and active ingredients valerian stimulates glutamate decarboxylase (which converts glutamate to GABA). The dual effect on GABA stimulates increased production of this neurotransmitter in the brain. Interaction with other plants, used for sedation, was studied during an objective analysis, while no side effects was not observed. The effectiveness of this combination in relation to sleep was significant.

The right combination of lemon balm and valerian is selected in natural preparation"Nervo-Vit". In addition to these two components, it also includes blue cyanosis and motherwort, which enhance the sedative effect of Nervo-Vit. The drug is required for use in sleep disorders, nervous disorders, decrease immune function, high blood pressure, normalization of the heart, as well as to prevent oxidative stress and protect against aging.

Other drugs have similar effects on plant-based"Motherwort P" and "Valerian P" with a pronounced sedative effect.

Melissa officinalis herb
Instructions for medical use- RU No. LP-000188

date last change: 19.04.2017

Dosage form

Grass crushed

Compound

Melissa officinalis herb

Description of the dosage form

A mixture of pieces of stems, leaves, flowers and buds, passing through a 7 mm sieve. Color grayish green to green. The smell is weak. Taste water extract slightly bitter.

Characteristic

Melissa officinalis herb contains essential oil, vitamins B l, B 2, C, tannins, coumarins, flavonoids, phenolic acids, ursolic acid.

Pharmacological group

A sedative of plant origin.

pharmachologic effect

Melissa officinalis herb infusion has a mild sedative effect, has moderate antispasmodic properties.

Indications

Applied in adults with increased emotional excitability, irritability, sleep disturbance (disturbed falling asleep, early awakening).

Contraindications

Hypersensitivity to the drug, drowsiness, lethargy, lethargy, childhood under 18 years old

Use during pregnancy and lactation

Perhaps if the expected benefit to the mother outweighs the potential risk to the fetus and child. It is necessary to consult a doctor.

Dosage and administration

About 2-3 g (1 tablespoon) of chopped herbs are placed in a glass or enamel bowl, pour 200 ml (1 cup) of boiling water, cover and heat in a boiling water bath for 15 minutes, cool at room temperature for 45 minutes, filter. The remaining raw material is squeezed out. The volume of the resulting infusion is adjusted with boiled water to 200 ml.

It is taken orally in a warm form, 1/2 -1/3 cup 2-3 times a day, 1 hour after meals. The course of treatment is 3-4 weeks.

Side effects

Allergic reactions are possible.

Overdose

To date, cases of overdose have not been registered.

Interaction

Enhances action sleeping pills and others medicines depressing the central nervous system.

special instructions

When individual intolerance infusion of lemon balm is replaced with valerian preparations.

Influence on the ability to drive vehicles, mechanisms.

During the treatment period, care must be taken when engaging in potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions (driving vehicles, working with moving mechanisms, the work of a dispatcher and operator).

Release form

Grass chopped 50 g in a cardboard pack with an inner paper, polymer or polypropylene bag.

The text of the instructions for use in full is applied to the pack.

Storage conditions

In a dry, dark place; prepared infusion - in a cool place for no more than 2 days. Keep out of the reach of children

Melissa or Lemon Balm is one of the most popular herbal remedies, the gentle scent of mint can help with headaches, irritation and insomnia. In addition, lemon balm has anti-inflammatory and decongestant properties, it is used to treat diseases. gastrointestinal tract, urinary system, heart and also in the treatment skin diseases- eczema, lichen, acne and so on.

Melissa ordinary - composition and useful properties

Melissa ordinary or lemon mint is a medicinal perennial plant from the mint family, people have known about its healing properties since ancient Rome. The eastern part of the Mediterranean is considered the birthplace of the plant, but for 2 thousand years this plant has spread throughout the world, gaining particular popularity in Russia and Europe. Today, lemon balm is grown for the preparation of essential oils, aromatization of cosmetics and detergents, and for treatment. various diseases. For medicinal purposes, use fresh or dried leaves collected before flowering plants. Young leaves and shoots of lemon mint contain:

• essential oils - up to 0.33%, they have a calming effect on the nervous system, removing excessive irritation and stabilizing the brain. In addition to a sedative, essential oils have a relaxing effect, relieving spasms of the smooth muscles of the intestines, urinary system and other organs;
• bitterness - activate the work of the digestive glands, increase the secretion of gastric juice and bile. They also improve metabolism, preventing the development of inflammation in the intestines;
• flavonoids - biologically active substances with anti-inflammatory, antioxidant and antibacterial activity;
• tannins - prevent inflammation, accelerate the healing of damage to the skin and mucous membranes;
• organic acids - are involved in all types of metabolism, especially important for fat and cholesterol metabolism;
• resins - disinfect wound surfaces, preventing the development of pathogenic bacteria on the mucous membranes, skin and internal organs.

The use of lemon balm in folk medicine

Melissa or heartwood is used to treat huge amount diseases:

• Diseases of the nervous system- lemon balm has a beneficial effect on the functioning of the brain and the nervous system as a whole. It has a calming and antidepressant effect, helps with headaches, migraines, increased irritability, stress or insomnia.
• Diseases of the gastrointestinal tract- antispasmodic and anti-inflammatory properties of lemon balm make it indispensable for flatulence, spasms of the stomach and intestines, gastritis and gastric and intestinal ulcers. In addition, lemon mint improves appetite, normalizes metabolism and activates digestion.
• diseases of cardio-vascular system - regular use lemon balm prevents the accumulation of cholesterol in the vessels, improves vascular tone and has a beneficial effect on the condition of the heart and blood vessels.
• Diseases of the female genital area- decoctions and infusions of lemon balm help to cope with painful menstruation, inflammatory diseases pelvic organs and some other diseases of the genital area.
• Skin diseases- decoctions and infusions of lemon balm are used to prepare baths, lotions and compresses for eczema, dermatitis, allergic diathesis, skin rashes, festering wounds and so on.

In addition, lemon balm is used for cosmetic purposes, during pregnancy and lactation - to treat toxicosis and increase the amount of breast milk, as well as for sexual weakness and for rinsing the mouth with an unpleasant odor.

Contraindications

Melissa vulgaris is one of the most effective medicinal plants, so you can take it only according to indications and do not exceed the recommended doses. Also, decoctions and infusions of lemon balm can not be taken orally with:

• epilepsy;
• hypotension;
• exacerbation of stomach or intestinal ulcers;
• liver failure;
• individual intolerance.

When treating with lemon balm, some inhibition of reactions, drowsiness and a decrease in concentration are possible. Therefore, the use of decoctions and infusions of lemon balm should be abandoned by drivers, people working with dangerous mechanisms and in jobs that require maximum concentration.

Melissa - recipes

Melissa infusion- used for diseases of the gastrointestinal tract and headaches, it also reduces pressure and improves heart function. To prepare the infusion 2 tbsp. l. dry leaves of lemon balm pour 2 tbsp. boiling water and leave to infuse for 3-4 hours, in a warm place. Take an infusion of 1/2 tbsp 2-3 times a day before meals. The course of treatment - from 14 days to 1 month.

Melissa decoction- used for treatment nervous diseases, insomnia, inflammation of the internal organs, anemia, diseases of the cardiovascular system and painful menstruation. To prepare a decoction 1 tbsp. l. dry leaves pour 1 tablespoon of boiling water, boil in a water bath for 5-10 minutes and leave to infuse for 1-2 hours. After that, filter and take 1/4 tbsp. 3 times a day before meals. The course of treatment is 10-14 days.

For outdoor use- for the treatment of wounds, abrasions and skin diseases, compresses and baths with lemon balm are used. For their preparation 2 tbsp. l. dry grass pour 1 tbsp. boiling water and leave to infuse for 10-15 minutes.

The resulting infusion is filtered and used for washing wounds, washing the face or preparing baths. The infusion is also used to prepare therapeutic compresses, in this case it is not filtered, but impregnated with a clean cotton cloth and applied to the wound.

Alcoholic infusion of lemon balm- helps with migraines, tinnitus, anemia, neuroses and insomnia. Prepare an infusion of fresh lemon mint leaves - 5 tbsp. l. fresh finely ground leaves pour 1 tbsp. 40% alcohol and insist for 7-10 days in a dark place, shaking occasionally. After that, the infusion is filtered and taken orally 1-15 drops at bedtime or 5 drops 3 times a day.

Also, this tool can be used to rinse the throat and gums - 1 tbsp. water 1 tsp. tinctures.

Melissa tea- unlike decoctions and tinctures, tea with lemon mint can be drunk daily without fear of slowing down reactions or overdose. This tea is useful for increased irritability, constant fatigue, nervousness, insomnia, frequent stress and overwork.

Also, this tea is recommended during pregnancy, it reduces the manifestations of toxicosis and helps to cope with headaches. Melissa tea improves appetite, normalizes the functioning of the cardiovascular system and strengthens the body. But in order for the drink to bring maximum benefit to the body, it must be brewed, in compliance with all the rules:

• water should cool after boiling, to about 80 degrees. When brewing tea with boiling water, not only the delicate taste and aroma of the drink is lost, but also its beneficial properties;
• tea is brewed only in glass or porcelain dishes - if you use metal, the tea will oxidize;
• Drink tea only freshly brewed. When preparing tea for 1 liter of water, 1 tbsp. l. black tea and 1 tsp. lemon balm. The mixture is brewed with warm water, covered with a lid and left for 5-10 minutes. Drink green tea 1 tbsp. 2-3 times a day, but not more than 3 cups per day.

Melissa essential oil Melissa essential oil is very popular. It is used in aromatherapy and simply to create a cozy and calm atmosphere in the house. Scientists have found that inhaling the vapors of lemon balm essential oil has a beneficial effect on the psyche, removing unnecessary irritation, calming and improving sleep.

When buying lemon balm oil in a pharmacy or specialized stores, you need to pay attention to whether this oil is pharmacy or cosmetic. The latter can only be used for flavoring rooms and cooking aromatic baths, it is impossible to take it inside categorically.

Pharmaceutical melissa oil is used for the preparation of inhalations for influenza, SARS, colds and other diseases of the upper respiratory tract. Solution for inhalation is prepared from 1 tbsp. l. honey, 3-5 drops of oil and 1 liter of boiling water. Pour boiling water over honey and oil and breathe over the steam for 15 minutes 3-4 times a day until recovery.

Melissa oil also helps with headaches. To get rid of discomfort it is enough to lubricate the whiskey with oil and lie down for 20 minutes, closing your eyes.

Melissa bath is considered one of the most effective relaxing and soothing remedies. To aromatize the bath, add 10-15 drops per 10 liters of water; additional salts should not be poured into such a bath, gels and conditioners should not be used. If you combine 5 drops of lemon balm oil with 5 drops of massage or vegetable oil and massage, you can get rid of pain in muscles and joints, relieve fatigue and tension.

Also, lemon balm oil is used during epidemics of influenza, SARS and other diseases transmitted by airborne droplets. It is enough to add a few drops of oil to an aroma lamp or place a soaked handkerchief near a heat source to disinfect the air from viruses and bacteria. Inhalation of lemon balm vapors will also help the disease that has already begun, a pleasant aroma will speed up recovery, improve sputum discharge and relieve headaches.

Pillows with melissa has long been used for sleeping. It is enough to fill a small cloth bag with dry grass and sweet Dreams will be provided.

Melissa officinalis
Taxon: family Lamiaceae ( Lamiaceae)
Other names: lemon grass, lemon mint, censer, bee mint
English: Common Balm, Lemon Balm

The origin of the name of the plant has three versions. In accordance with the first, it comes from the Greek words "meli" - honey and "phyllon" - leaves, and is given to the plant for its honey smell. The second version is of mythological origin. Melissa, according to Greek mythology, a nymph, the daughter of King Melisseus, who fed Zeus with milk and honey, and was supposed to teach people how to get honey. According to the third version, Melissa was a very beautiful woman and claimed to be the first mistress of the gods. However, the goddesses did not like this, and they turned Melissa into an ordinary bee.

Botanical description lemon balm

Melissa officinalis is a perennial herbaceous plant 30–150 cm high. The stem is branched, tetrahedral, the whole plant is soft-haired. Leaves heart-shaped-ovate, coarsely toothed, petiolate, opposite. Flowers small, on short stalks, pale pink, lavender or white, in axillary fascicles. Blooms in July-August. The fruit consists of 4 egg-shaped nuts. The whole plant has a pleasant lemon smell before flowering, which weakens and even becomes unpleasant after flowering. The fruits ripen in August-September.

Spreading

Melissa is native to the Middle East and North Africa. It is believed that the Arabs brought it to Spain around 960 AD. e. In the Middle Ages, the plant spread in Western and Central Europe. In most Mediterranean countries (from Italy and Syria to the Caucasus), lemon balm has grown wild and grows like a weed among shady shrubs, in light forests, on rocky and grassy places. In some countries, its range reaches an altitude of 1000 m above sea level.
Currently, lemon balm is cultivated in many countries, including Russia (Krasnodar Territory, Samara Region), Lithuania. Melissa is widely cultivated in vegetable gardens, orchards and plantations. In Europe, varieties with a high content of essential oil and citral have been bred.

Collection and preparation of medicinal raw materials of lemon balm

WITH therapeutic purpose use leaves (Folium Melissae) and tops of shoots (Herba Melissae), which are harvested at the beginning of flowering. When harvesting raw materials, the mass is first dried in air in the shade or in cold dryers (at a temperature not exceeding 40 ° C) and stored in a well-ventilated area. You can get 3-4 crops per season. It is better to collect lemon balm at noon, in cloudy weather, to reduce the loss of essential oil.
The aerial part and leaves of lemon balm are official raw materials in Russia, Italy, France, Germany, Poland, the Czech Republic, Great Britain and other European countries.

Biologically active substances of lemon balm

The medicinal properties of lemon balm are due to the essential oil localized in the essential oil glands. The first studies of terpene compounds contained in lemon balm oil were carried out at the end of the 19th century, in 1891–1894. Citral and citronelal were isolated from the plant, and over time, monoterpene compounds - geraniol, linalool and citronelol. It is citral that gives the raw material a pleasant lemon smell.
As a result of modern research, up to 65 terpenoids have been identified in the essential oil and leaves of lemon balm, the main of which are neral (citral b) and geranial (citral a), and citronelol predominates in the essential oil of old leaves. Some scientists consider caryophyllene oxide as a specific terpene for lemon balm, which can serve to identify raw materials.
New studies by Turkish scientists show that the essential oil contains 15.41% β-cubeben, 3.5-14.24% β-caryophyllene, 7.59% sesquiterpene alcohol, 7.18% α-cadinol, 6.62-44 .9% geranial, 3.96% cadinol, 2.92-21.1% citronelal, 5.82-33.3% neral, 2.36% neraldiol, 0.6-1.2% linalool, 0.4 -0.5% 3-octyl acetate, 0.3-0.8% trans-2-hexanal, 0.2-0.6% ocimene V (trans), 0.6% perylaldehyde. Melissa essential oil also contains myrcene, lavandulomevalerate, geranyl acetate, caryophyllene oxide, n-cymol, 1-octen-3-ol, 3-(1-octenyl) acetate, trans-2-noneal, 2,4-decadienal, trans -2-decenol, α-cubeben, α-copaene, α-caryophyllene, β-bourbonene, thujopsen, valencen.
Young leaves and leaves of the first collection contain up to 0.29% essential oil, the second collection - up to 0.13%, the third - only 0.1%. The content of essential oil in dry raw materials is affected by the timing of collection, drying, grinding and packaging. It should be noted that the amount of essential oil in lemon balm leaves is unstable. When extracting and heating the essential oil, the cyclization of citronelol takes place.
Melissa leaves contain phenylcarboxylic acids and their depsides: caffeic acid, its dimer - rosmarinic acid and trimers - melitric acids A and B, as well as chlorogenic acid (depsid of caffeic and quinic acids). Using high-performance liquid chromatography, it was found that the content of rosmarinic acid in lemon balm leaves ranges from 0.54 to 1.79% (according to other authors - up to 4.7%). In addition, lemon balm leaves contain p-coumaric, ferulic, p-hydroxybenzoic, protocatechuic, gentisic, synapic, syringic, vanillic and salicylic acids.
Lemon balm leaves contain small amounts of flavonoids such as luteolin 7-O-glycoside, cosmocyin - apigenin 7-O-glycoside and flavonol glycosides: rhamnocitrin - 7-methoxykaempferol and isoquercitrin - quercitrin 3-glycoside.
Melissa leaves also contain triterpenes - ursolic and oleanolic acids (0.50% and 0.17%, respectively) and their derivatives, terpenoids - glucosides of nerol, geraniol, nerolic acid. They contain bitterness, coumarins (esculetin), up to 5% tannins, succinic acid, mucus, stachyose tetrasaccharide (combination of two galactose residues with glucose and fructose), carotene (0.007–0.01%), vitamins C (0.15%), B1, B2, E.
Lemon balm seeds contain up to 20% fatty oil.

The history of the use of lemon balm in medicine

Melissa officinalis began to be used in medicine more than 2000 years ago. It has been cultivated in Ancient Greece and Rome. Melissa also had wide application as a valuable honey plant, as evidenced by the treatises of Theophrastus (227–287 BC). One of the heroes of the Theocritus myth, Laocoön, ate lemon balm. Virgil Maro (70-19 BC), Pliny the Elder and the Greek physician Dioscorides (1st century BC) pointed out that beekeepers rubbed their bodies with fresh lemon balm leaves to catch a swarm of bees. The ancient Greeks called lemon balm "kalaminta" or "melissophyllon". In Rome it was known under the name "apiastrum".

Ancient medicine attributed antimicrobial, antiseptic, antidysenteric, sedative effects to lemon balm, the plant helped to improve vision and.

The Arab physician Avicenna (979-1037) believed that lemon balm refreshes and strengthens the heart, and helps with hiccups. He recommended lemon balm as a tonic and for the treatment of melancholy.

Arabs began to grow lemon balm in Europe at the beginning of the 16th century. in Spain. Melissa was one of the most popular plants in medieval Europe. In the capitularies of Charlemagne, it was indicated that it should be grown in every garden. The medieval German healer and Benedictine abbess Saint Hildegarde of Bingen (1098–1179) recommended that lemon balm be consumed as well as depressant with headaches, in particular with. Seraphim the Younger (second half of the 12th century) argued that lemon balm leaves can cheer up, drive away boredom, fear and sadness. Melissa was highly valued by Paracelsus (1493-1541). He equated the properties of lemon balm in terms of strength to gold.

The Polish medieval physician Sireniusz (1541–1611) recommended the use of lemon balm for, as well as, the gastrointestinal tract.

Especially popular in the Middle Ages was "Carmelite lemon balm water", which was made by the French Carmelite monks from lemon balm leaves with the addition of mint leaves, lemon peel, coriander seeds, nutmeg and cinnamon. Such water treated diseases of the nervous system.

Medieval magicians and sorcerers attached magical significance to lemon balm. Priests of ancient temples prepared a dynamized drink from lemon balm. Together with wormwood abrotan (God's tree) ( Artemisia abrotanum L.) and emerald melissa was part of the remedy used to reduce pain during childbirth. As Albert the Great pointed out, whoever wears lemon balm on himself will be loved by everyone, and if you hang it on the neck of a bull, he will be obedient.

In 1522, lemon balm herb was included in the German Register of Brunswick. medicines, and the essential oil was included in the Catalogus of Frankfurt, published in 1582. Hieronymus Bok in 1539 made a wine-melissa distillate called Cardiaca, which was used as a heart and stomach remedy.

In Rus', traditional medicine used decoctions of lemon balm for stomach cramps, "nervous fevers", insomnia, melancholy, hysteria, and, with, bronchial asthma, algomenorrhea and painful menstruation, as an anticonvulsant, expectorant and remedy for. The plant is recommended as an antiemetic for pregnant women. In addition, "melissa oil" was sometimes used, 3-6 drops per sugar. IN traditional medicine In Lithuania, an infusion of lemon balm and marjoram was used to improve memory. Melissa is recommended in the form of aromatic baths for skin diseases. Compresses from the leaves and tops of the shoots of lemon balm are used for rheumatic pains in the joints and muscles, bruises, ulcers.

Pharmacological properties of lemon balm

Medicines, which include lemon balm, have pronounced sedative, antispasmodic and carminative properties. Melissa has been found to have a mild effect. Such pharmacological activity is mainly due to the components of the essential oil. and antispasmodic effect is manifested when using small doses of lemon balm, and their subsequent increase does not enhance these effects.

Electrophysiological studies carried out by E. Holm have established that the target of the action of lemon balm essential oil compounds is the brain, namely, the limbic system, which controls vegetative functions and also screens large hemispheres from very strong stimuli coming from the periphery. These data experimentally determine the therapeutic efficacy of lemon balm in vegetative-vascular dystonia. R. F. Weiss (1985) concludes that lemon balm belongs to mild phytotranquilizers.

D. Yordanov et al. (1971) indicate that lemon balm increases appetite, stimulates the secretion of gastric juice, and eliminates fermentation anomalies.

Melissa tincture exhibits a protective effect in experimental gastric ulcer. At the same time, it was found that it enhances gastric motility, has choleretic and hemostatic properties.

The antispasmodic effect of lemon balm was established on experimental animals. Its tincture reduces the tension of the smooth muscles of the intestine, exhibits bronchodilator properties. The essential oil of lemon balm relaxes catecholamine-induced spasm of the smooth muscles of the trachea and phase contractions of the longitudinal strips of the small intestine of guinea pigs.

H. Leclerc (1976) reported that lemon balm exhibits antiarrhythmic activity and can be successfully used for various types of cardiac arrhythmias, as well as for nervous tremors that occur at night. It slows down breathing, reduces heart rate, lowers blood pressure.

Melissa herb has astringent hypoglycemic and diuretic properties, stimulates menstruation.

Melissa exhibits anti-inflammatory, bacteriostatic and antiviral properties. K. Okazaki and S. Oshima (1953) conducted research antimicrobial activity essential oil components against a number of pathogenic fungi and Mycobacterium tuberculosis. Aldehydes (citral, citronelal) were the most active, and alcohols (geraniol) were less active. The antimicrobial properties of lemon balm essential oil are more pronounced than those of essential oils of other representatives of the labiate family, in particular lavender and rosemary.

Melissa essential oil has antiviral activity against viruses, Semilka forest disease, influenza, measles and Nyocastle disease. Back in 1968, E. C. Herrmann and L. S. Kucera established that it is due to rosmarinic acid. Further research by Bulgarian scientists ( Z. Dimitrova et al., 1993) demonstrated a direct virucidal effect of the melissa extract fraction, which contains caffeic, ferulic and rosmarinic acids, when exposed to the virus. simple type 1 for 3 and 6 hours. It should be noted that the antiviral effect of lemon balm preparations has low selectivity, and they can be used against myxoviruses - influenza viruses A and B. Recently, A. Mazumder et al. (1997) found that rosmarinic acid blocks the binding of human immunodeficiency virus (HIV-1) integrase to provirus DNA and, apparently, inhibits its integration into the cell chromosome.

It is with rosmarinic acid in to a large extent due to the anti-inflammatory and antioxidant effect of the water-alcohol extract of lemon balm. In experiments in vitro, it inhibits LPO processes in microsomes of the brain, liver, and kidneys of rats induced by Fe2+/cysteine ​​and vitamin C/NADP (formation of malondialdehyde), as well as the formation of superoxide anions in the xanthine/xanthine oxidase system. Rosmarinic acid reversely inhibits luminol-dependent chemiluminescence of human segmented nuclear granulocytes induced by opsonized Staph. aureus, opsonized zymosan and phorbol myristate acetate, i.e. the secretion of oxygen and H2O2 free radicals by these cells. But at the same time, rosmarinic acid does not affect the migration of polymorphonuclear cells under the influence of chemoattractants, their absorption capacity in relation to Staph. aureus and on the level of oxygen consumption by these cells during phagocytosis. In the presence of rosmarinic acid, the intensity of hemolysis of erythrocytes decreases under the influence of hydrogen peroxide and polymorphonuclear cells stimulated by phorbol myristate acetate. It is believed that it binds free oxygen radicals in the extracellular environment. Anti-inflammatory and antioxidant properties rosmarinic acid also appear in in vivo experiments. Its administration to rabbits after an intravenous injection of zymosan-activated blood plasma prevents the development of interstitial pulmonary edema and the accumulation of polymorphonuclear cells in them, reduces the histological signs of inflammation in other organs (but the number of circulating neutrophils and platelets does not decrease). Due to its antioxidant activity, rosmarinic acid affects the process of 5-lipoxygenase oxidation. arachidonic acid. At concentrations of 0.01-1 mM, it is a strong inhibitor of the synthesis of 5-hydroxy-6,8,11,14-eicosatetraenoic acid and leukotriene B4 - important inflammatory mediators - by segmentonuclear granulocytes of human peripheral blood stimulated by calcium ionophore A 23187.

The anti-inflammatory properties of rosmarinic acid are also due to anti-complement activity. It inhibits the activity of C3 convertase of the classical and alternative pathways of complement activation, as well as C5 convertase, and to a lesser extent affects the binding of the C1q component. In vitro experiments found that rosmarinic acid inhibits complement-dependent hemolysis of sheep erythrocytes (at optimal concentrations of 5–10 μM - by 70%), and its effect on the classical pathway of complement activation is stronger than on the alternative one. In connection with anticomplementary activity, rosmarinic acid inhibits phagocytosis in the absorption phase. coli segmentonuclear granulocytes of humans and pigs, but it does not directly affect the intracellular killing of microorganisms. The anticomplementary activity of rosmarinic acid is also manifested in vivo: at doses of 0.316–3.16 mg/kg intramuscularly, it inhibits the development of rat paw edema under the influence of cobra venom, and at doses of 1–100 mg/kg per os, it inhibits the development of passive anaphylaxis in rats. At a dose of 10 mg/kg intramuscularly, rosmarinic acid counteracts macrophage activation in mice induced by intraperitoneal administration of heat-killed Corynebacterium parvum. At a dose of 20 mg/kg intravenously, it inhibits the occurrence clinical manifestations endotoxic shock in rabbits - hemocirculatory (hypotension) and hematological changes (thrombocytopenia), which are manifestations of the early phase. The basis of the therapeutic effect of rosmarinic acid is the inhibition of the activation of the complement system and synthesis, as well as the release into bloodstream vasoactive prostanoids (prostacyclin and thromboxane A2), which plays a key role in the pathogenesis of the early phase of endotoxic shock. In particular, it has been proven that rosmarinic acid prevents an increase in the level of complement-dependent synthesis of prostacyclin (prostaglandin I2) by rabbit peritoneal tissue during its incubation with fresh serum and cobra venom.

In connection with the anticomplementary properties of H. Bult et al. (1985) and P. W. Peake et al. (1991) consider rosmarinic acid and lemon balm extract to be promising for the treatment of endotoxic shock and other immunopathological conditions caused by excessive activation of the complement system.

In addition to anti-complementary and anti-radical activity, the anti-inflammatory effect of rosmarinic acid is based on its ability to inhibit the activity of lysosomal proteases (elastase, serine proteases).

Rosmarinic acid is well absorbed through the skin - after 4.5 hours it is found in the blood, skin, muscle and bone tissues. 30 minutes after intravenous administration to rats, rosmarinic acid accumulates in significant amounts in the tissues of the brain, heart, liver, lungs, muscles, spleen and bone tissue. Its high content is noted in the lungs (13 times higher than the concentration in the blood), spleen, heart and liver. Therefore, rosmarinic acid is considered as a promising non-steroidal anti-inflammatory agent for clinical use ( W. A. ​​Ritschel et al., 1989). Animal studies have confirmed its efficacy in local treatment experimental gingivitis.

Anti-inflammatory and anti-complementary activity underlies the anti-allergic action of rosmarinic acid.

In experiments on rats, Z. W. Zou et al. (1993) established the antithrombotic properties of rosmarinic acid, which are associated with inhibition of platelet aggregation and increased fibrinolytic activity of blood plasma. At doses of 50 and 100 mg/kg, it significantly inhibits the formation of venous thrombi (by 41.9% and 54.8%, respectively), platelet aggregation induced by collagen (by 30.4% and 46.4%), reduces the euglobulinolytic period, without affecting the level of fibrinogen in plasma.

Of practical interest to clinicians is the message of M. Aufmkolk et al., that the dried frozen extract of lemon balm blocks binding to receptors thyroid-stimulating hormone Graves' immunoglobulins - IgG, which activate the intrasecretory function thyroid gland(which underlies the pathogenesis of toxic diffuse goiter- Graves-Basedow disease). At the same time, the biological activity of Graves' immunoglobulins is blocked, judging by the activity of adenylate cyclase and the release of iodine-containing thyroid hormones.

In experiments on mice, it was found that the polyphenols of the water extract of lemon balm stimulate the primary and secondary humoral immune response to ram erythrocytes.

Experimentally confirmed cytostatic effect aqueous extracts lemon balm. In the extract of melissa leaves, which does not contain tannins, two compounds (caffeic acid and an unidentified glycoside) have been identified that inhibit protein synthesis in a cell-free system. The glycosidic inhibitor affects the EF-2 elongation factor by blocking its binding to ribosomes.

Toxicology and side effect lemon balm

The plant is low toxic, but lemon balm should not be used when.
When using lemon balm preparations, dizziness, lethargy, fatigue, drowsiness, decreased concentration, nausea, vomiting, itching, exanthema, muscle weakness, convulsions are possible. Therefore, patients undergoing treatment with lemon balm preparations should avoid potentially dangerous species activities that require heightened attention, fast motor and mental reaction (driving Vehicle, mechanism control).

Clinical use of lemon balm

Melissa leaf extracts are used as an effective sedative, especially in geriatric practice. This makes it possible to reduce the dose of synthetic drugs or to abandon them altogether. The plant is prescribed for conditions of general nervous excitement, hysteria, insomnia, functional pain in the heart, tachycardia, and changes blood pressure under the influence of emotional factors, dizziness, tinnitus, painful menstruation, postpartum weakness.

Medicines from lemon balm are also prescribed to increase appetite, with digestive disorders, epigastric pain, stomach neurosis, gastritis, colitis, asthma, and neuralgia. D. Yordanov et al. (1971) describe positive influence of this plant for some functional disorders digestive system. When recommend enemas with lemon balm juice. Infusion of lemon balm leaf, collected before flowering, is used as a diuretic.

Externally, lemon balm is prescribed for baths and compresses for allergic dermatosis, furunculosis, as well as in cosmetology. IN dental practice it is used for rinsing oral cavity with gingivitis.

Melissa water, essential oil of lemon balm and lemon balm alcohol are used in medicine. Melissa alcohol is prescribed externally for rubbing with neuralgia, headaches, and also in the evening before bedtime with insomnia. IN German medicine a popular remedy is a complex lemon balm spirit (or "Carmelite spirit"), which, in addition to the essential oil of lemon balm, contains nutmeg, cinnamon and clove oils. It is used in 10-20 drops in water.

Lemon balm leaf is rarely used on its own, more often it is used in conjunction with mint, chamomile, cumin, hysop, valerian, lavender, hawthorn and other medicinal plants. Dry lemon balm leaves are used to flavor teas. The composition of the therapeutic and prophylactic diet includes salads from the young foliage of the plant. A leaf of lemon balm, fresh or dried, is used as a spicy seasoning in cooking (for soups, mushrooms, for fish and meat dishes, when canning vegetables) and in the alcoholic beverage industry. In Denmark, lemon balm is used to preserve meat.

The essential oil of lemon balm is part of the balm and liniment "Sanitas" (together with methyl salicylate, purified turpentine oil, eucalyptus oil and camphor), which have a sedative effect.

Medicines containing lemon balm

Altalex(Altalex, Lek, Slovenia) - drops containing a 2.5% mixture of essential oils of lemon balm, peppermint, fennel, cloves, thyme, pine needles, anise, sage, cinnamon and lavender in an ethanol solution. Produced in bottles of 50 ml.
Has antispasmodic, diuretic, choleretic properties, mild sedative effect, stimulates secretory activity digestive tract. It is prescribed orally (10-20 drops in hot tea 30 minutes before meals 3 times a day) for flatulence and other dysfunctions of the gastrointestinal tract, diseases of the hepatobiliary system, menopausal syndrome, painful menstruation. Children from 3 to 5 years old are prescribed 1/3 dose for adults, from 6 to 9 years - 1/2 dose for adults. It is also used externally - for rubbing with arthritis, myalgia.

Novo-Passit(Novo-Passit, Galena, Czech Republic) - a preparation in the form of an oral solution, 5 ml of which contains 200 mg of guaifenesin and 150 mg of a complex of extracts of medicinal plants (common hawthorn, common hop, St. John's wort, lemon balm, passionflower, black elderberry and valerian officinalis). Produced in bottles of 100 ml.
The drug exhibits a sedative and anxiolytic (tranquilizing) effect. Eliminates the feeling of fear, mental stress, relaxes smooth muscles.
Indications: constant mental stress ("manager's syndrome"); mild forms of neurasthenia, accompanied by irritability, anxiety, fear, fatigue, absent-mindedness, memory impairment, mental exhaustion; insomnia; , attacks of headaches caused by nervous tension; increased neuromuscular excitability; climacteric syndrome; functional diseases digestive tract (dyspeptic syndrome, irritable bowel syndrome); cardiopsychoneurosis; dermatoses accompanied by itching ( atopic eczema, seborrheic eczema, urticaria).
Assign 5 ml (1 teaspoon) of the drug 3 times a day. If necessary, a single dose is increased to 10 ml. When inhibition occurs, 2.5 ml is prescribed in the morning and afternoon, and 5 ml at night. The drug can be taken once, 5-10 ml 20-30 minutes before the predicted emotional load. In case of digestive disorders, the drug is recommended to be taken with meals.
Novo-Passit is contraindicated in myasthenia, hypersensitivity to its components. Caution should be given to patients with severe organic diseases of the gastrointestinal tract. The drug enhances the effect of substances that depress the central nervous system, as well as alcohol. Novo-Passit is not recommended for children under 12 years of age.
Side effects: possible dizziness, lethargy, fatigue, drowsiness, decreased concentration, nausea, vomiting, itching, exanthema, muscle weakness, convulsions; potentially hazardous activities that require increased attention, fast motor and mental reactions (driving vehicles, operating mechanisms) should be avoided.

Persen(Persen, Lek, Slovenia) - dragees containing 50 mg of valerian extract, 25 mg of peppermint extract, 25 mg of lemon balm extract. Produced in a package of 40 tablets.
Persen forte(Persen forte, Lek, Slovenia) - capsules containing 125 mg of valerian extract, 25 mg of peppermint extract and 25 mg of lemon balm extract. Available in a pack of 20 capsules.
Renders sedative effect on the central and autonomic nervous system, normalizes sleep and appetite in case of neurosis, asthenia. It is prescribed for neuroses, asthenovegetative syndrome, which manifests itself increased fatigue, irritability, psycho-emotional stress or depression, decreased concentration, memory impairment, insomnia, sweating and hand tremors. With psychosomatic lability, fear, tension, anxiety and irritability. Apply 2 tablets 2-3 times a day or 1 capsule an hour before bedtime. Children after 6 years of age are prescribed 1 tablet 2-3 times a day.

Calmidorm(Medisculab, Germany) - drops, 100 ml of which contains alcoholic extracts of valerian root (1:1) - 27 g, lemon balm leaf (10:8) - 20 g and passionflower grass (10:7) - 53 g. Apply 20 -25 drops 3 times a day for anxiety and insomnia.

Kneipp Nerven– und Schlaf– Tee N(Kneipp, Germany) - tea, 100 g of which contains 56.7 g of lemon balm leaf, 31.6 g of valerian root and 12.3 g of orange peel malt. Assign as a sedative 1-2 cups during the day and 2 cups in the evening.

Melissa essential oil is part of a multicomponent preparation Doppelhertz(Doppelherz, Queisser Pharma), which has tonic and restorative properties. It is used for increased physical and mental stress, polyhypovitaminosis and beriberi, neurosis, in menopause and convalescence, in geriatrics - as a tonic. Assign inside 1 measuring glass (20 ml) 3-4 times a day before meals and at night before going to bed.

Application in industry

Melissa is a valuable honey plant, during flowering it gives a lot of nectar.

Photos and illustrations