Substitutes for imported drugs with domestic ones. Some expensive drugs and their alternatives

Having addressed your illness to a doctor and received from him an impressive list medicines, the patient rarely questions it. And only after finding out the cost necessary medications, a person wonders: are the medications prescribed by the doctor effective, and do they have cheaper analogues? This question undoubtedly interests everyone, and therefore in this article we will answer a number of questions:

What cheap domestic analogues of expensive drugs can be found on the shelves of our pharmacies?
Why are these drugs so cheap?
Can they provide a therapeutic effect that is not inferior to the original drugs?

But first things first.

What are generics?

Analogs of expensive medications are called generics all over the world. In fact, these are reproduced “copies” of original medicines for which the patent has expired. Generics have the same active substance as the original medicine and a similar dosage. They differ only auxiliary components, which means there is no doubt that the therapeutic result of the original and the “copy” is practically no different.

Why are generics so cheap?

Many people are alarmed by the low cost of generics, because it is completely unclear why a “copy” that is in no way inferior to the original medicine costs several times less? In fact big secret there is no. Unlike the original, generic manufacturers do not spend a penny on the development of the active substance, which means they do not include the costs of experiments and testing in the price. In addition, domestic drugs, unlike foreign originals, are not subject to import duties and taxes. All this ultimately allows us to create a much more reasonable price.

Other advantages of generics

Low price while maintaining a decent therapeutic effect is by no means the only advantage domestic analogues expensive drugs. A huge advantage of these drugs is that they are not counterfeited (this is simply unprofitable!). In addition, the assessment of the quality and safety of domestic drugs is growing year by year, which means that the population Russian Federation trusts these remedies much more than the same Vietnamese or Chinese medicines.

Disadvantages of Generics

Considering that generics are still “copies” of original medicines, they do not fully correspond to the original and this should not be forgotten. We list their disadvantages:

1. They are characterized by a lower degree of purification, which means big list side effects. Indeed, the low cost of generics is also explained by the low degree of purification of the drug, which increases the number of side effects. Original medicines benefit significantly in this regard.

2. In comparison with the originals, generics, as a rule, have a “stripped-down” composition. For example, the original medicine can have an anti-inflammatory effect and at the same time reduce temperature, while its more cheap analogue will act in only one direction.

3. Original products have a high cost not only because of the high degree of purification and multi-component composition. Unlike analogues, their effect is much longer, and they need to be taken less often.

And yet, given the serious difference in cost and the same therapeutic effect (compare Omez and Omeprazole, Fervex and Paracetamol), modern clinic visitors increasingly prefer domestic analogues of the original foreign medicines. Below is a complete list of these medications and their substitutes.

List of cheap domestic analogues of expensive drugs

Antispasmodic and analgesic drugs, antipyretics

Cardiac and antihypertensive drugs

Antibacterial, anti-inflammatory and antiviral agents

Antidiarrheals

Antiallergic drugs

Inhalation drugs, cough suppressants

Sedatives and drugs that improve cerebral circulation

Gels, ointments and creams for external use

Other medications

Actrapid NM	Humulin NPH
Potassium and magnesium aspartate	Asparkam
Vinblastine-Teva	Vinblastine-Lance
Sermion	Nicergoline
Oftan dexamethasone	Dexamethasone
Timolol	Okumed
Hypothiazide	Hydrochlorodiazide
Vermox	Mebendazole
Iodomarin	Potassium iodide
Troxevasin	Troxerutin
Finlepsin	Carbamazepine
Mezim	Pancreatin
Movalis	Meloxicam

Dear subscribers, today we will talk about analogues of medicines and their prices - or more precisely, about cheap Russian analogues of expensive imported medicines. As the famous Soviet satirist and humorist Raikin would say: “They are fooling our brother!” But this is true, and doctors often prescribe a more expensive drug, knowing that there is a cheaper option.

And all because they are interested in it. They will also tell you where to buy the pharmacy. There is a conspiracy. I certainly don’t want to slander anyone. In addition, sometimes taking analogues does not give sustainable results. After all, expensive and cheap medicine is like eating in a restaurant or eatery. The ingredients are the same, but the quality is different...

Table of cheap analogues of expensive drugs with prices for 2017

However, if you do not want to overpay for packaging and for the name, then look at the tables in which you can find all the main equivalents of expensive drugs. There are also for colds and other problems.

Prices in rubles change upward due to inflation, so the amounts in the tables may be slightly out of date. But general idea you can get it, and the name of the drug does not change depending on the price. So the information is up to date!

Drug analogues - Antipyretics, antispasmodics, blood pressure, for the brain

Drug analogues - Antibiotics, antivirals

The difference in price can be seen without much stress. What you buy in the end is of course up to you. In the end, it may not be difficult for someone to pay 1000 rubles for a box of medicine.

But we must also remember that the price in no way determines the authenticity of the product. And there is a great temptation to counterfeit expensive pills. And no one will bother with cheap ones. There is no benefit.

Drug analogues - Clipping from Russian Newspaper

List of expensive and cheap similar drugs

Interchangeable drugs

Affordable analogues of expensive drugs

Some expensive drugs and their alternatives

Cost of original drugs and generics

Interchangeable foreign and domestic drugs

It would be useful to learn how to recognize counterfeit medicines

Doctors' opinions - synonyms for expensive drugs - should you trust online tables?

A complete list of expensive drugs and their cheap analogues - from A to Z

If you didn’t find something in the tables, you can still go through this list below. If the list does not contain the analogue you need, then ask questions in the comments. I’ll ask our pharmacist, she has 30 years of pharmacy experience and she is aware of everything related to the interchangeability of drugs.

B

Expensive Belosalik - cheap Akriderm SK

Expensive Bepanthen - cheap Dexpanthenol

Expensive Betaserc - cheap Betahistine

Expensive Bystrumgel - cheap Ketoprofen

IN

Expensive Voltaren - cheap Diclofenac

G

Expensive Gastrozole - cheap Omeprazole

D

Expensive Detralex - cheap Venarus

Expensive Diprosalik - cheap Akriderm SK

Expensive Diflucan - cheap Fluconazole

Expensive Dlynos - cheap Rhinostop

Z

Expensive Zantac - cheap Ranitidine

Expensive Zyrtec - cheap Cetirinax

Expensive Zovirax - cheap Acyclovir

AND

Expensive Immunal - cheap Echinacea

Expensive Imodium - cheap Loperamide

Y

Expensive Iodomarin - cheap Potassium iodide

TO

Expensive Cavinton - cheap Vinpocetine

Expensive Claritin - cheap Loragexal

Expensive Klacid - cheap Clarithromycin

L

Expensive Lazolvan - cheap Ambroxol

Expensive Lamisil - cheap Terbinafine

Expensive Lyoton-1000 - cheap Heparin-acri gel 1000

Expensive Lomilan - cheap Loragexal

M

Expensive Maxidex - cheap Dexamethasone

Expensive Mezim - cheap Pancreatin

Expensive Midriacil - cheap Tropicamide.

Expensive Miramistin - cheap Chlorhexidine

Expensive Movalis - cheap Meloxicam

N

Expensive Neuromultivit - cheap Pentovit

Expensive No-shpa - cheap Drotaverine

Expensive Normodipine - cheap Amlodipine

Expensive Nurofen - cheap Ibuprofen

ABOUT

Expensive Omez - cheap Omeprazole

P

Expensive Panadol - cheap Paracetamol

Expensive Panangin - cheap Asparkam

Expensive Pantogam - cheap Pantocalcin

R

Expensive Rinonorm - cheap Rinostop

WITH

Expensive Sumamed - cheap Azithromycin

T

Expensive Trental - cheap Pentoxifylline

Expensive Trichopolum - cheap Metronidazole

Expensive Troxevasin - cheap Troxerutin

U

Expensive Ultop - cheap Omeprazole

Expensive Ursofalk - cheap Ursosan

F

Expensive Fastum-gel - cheap Ketoprofen

Expensive Finlepsin - cheap Carbamazepine

Expensive Flucostat - cheap Fluconazole

Dear Furamag - cheap Furagin

X

Expensive Hemomycin - cheap Azithromycin

E

Expensive Enap - cheap Enalapril

Expensive Ersefuril - cheap Furazolidone

Extended list of cheap analogues of expensive drugs with descriptions

Belosalik and analog Akriderm SK

Active substance:
Indications:

Bepanthen and analogue Dexpanthenol

Active substance: dexpanthenol.
Indications: Prevention and treatment of dry skin when the integrity of its integument is violated: care of the mammary glands during feeding (treatment of “dry” nipples and painful cracks); prevention and treatment of diaper rash in infants; minor injuries, burns, abrasions, bedsores, aseptic postoperative wounds; cervical erosion.

Betaserc and analogue Betagistin

Active substance: betahistine.
Indications: dropsy of the labyrinth of the inner ear, vestibular and labyrinthine disorders: dizziness, noise and pain in the ears, headache, nausea, vomiting, hearing loss; vestibular neuronitis, labyrinthitis, benign positional vertigo(including after neurosurgical operations), Meniere's disease. Complex therapy includes vertebrobasilar insufficiency, post-traumatic encephalopathy, cerebral atherosclerosis.

Bystrumgel and analogue Ketoprofen

Active substance: ketoprofen.
Indications:

Voltaren and analogue Diclofenac

Active substance: diclofenac.
Indications: Inflammatory and inflammation-activated degenerative forms of rheumatism: - chronic polyarthritis; — ankylosing spondylitis (ankylosing spondylitis); - arthrosis; — spondyloarthrosis; - neuritis and neuralgia, such as cervical syndrome, lumbago (lumbago), sciatica; — acute attacks gout Rheumatic lesions soft tissues. Painful swelling or inflammation after injury or surgery.

Gastrozole and analogue Omeprazole

Active substance: omeprazole
Indications:

Heptral and analog Heptor

Active substance: Ademetionine.
Indications: Chronic cholecystitis, cholangitis, intrahepatic cholestasis, toxic lesions liver, incl. alcoholic, viral and medicinal origin (antibiotics, antitumor, antituberculosis, antiviral drugs, tricyclic antidepressants, oral contraceptives), fatty degeneration liver, chronic hepatitis, liver cirrhosis, encephalopathy, incl. associated with liver failure (alcohol, etc.). Depression (including secondary), withdrawal syndrome.

De-nol and analogue of Gastro-norm

Active substance: Bismuth tripotassium dicitrate
Indications: peptic ulcer and duodenum in the acute phase, incl. associated with Helicobacter pylori; chronic gastritis and gastroduodenitis, incl. associated with Helicobacter pylori, in the acute phase; other gastrointestinal diseases associated with Helicobacter pylori; dyspepsia not associated with organic diseases Gastrointestinal tract; treatment and prevention of gastropathy caused by taking NSAIDs.

Detralex and analogue Venarus

Active substance: diosmin and hesperidin
Indications: venous insufficiency lower limbs(functional, organic): feeling of heaviness in the legs, pain, cramps, trophic disorders; acute hemorrhoidal attack.

Diprosalik and analog Akriderm SK

Active substance: betamethasone and salicylic acid.
Indications: psoriasis, eczema (especially chronic), ichthyosis, limited prurigo with severe lichenification, atopic dermatitis, diffuse neurodermatitis; simple and allergic dermatitis; urticaria, exudative erythema multiforme; simple chronic lichen (limited neurodermatitis). Dermatoses that are not amenable to treatment with other corticosteroids (especially verrucous verrucous), red lichen planus, skin dyshidrosis.

Diflucan and analogue Fluconazole

Active substance: fluconazole.
Indications: Systemic lesions caused by Cryptococcus fungi, including meningitis, sepsis, lung and skin infections, both in patients with a normal immune response and in patients with various forms immunosuppression. Generalized candidiasis: candidemia, disseminated candidiasis. Genital candidiasis: vaginal (acute and recurrent), balanitis. Prevention of fungal infections in patients with malignant tumors during chemotherapy or radiation therapy. Mycoses of the skin: feet, body, groin area, onychomycosis, pityriasis versicolor, skin candidiasis infections. Deep endemic mycoses (coccidioidosis, sporotrichosis and histoplasmosis) in patients with normal immunity.

For nose and analogue Rinostop

Active substance: xylometazoline.
Indications:

Zantac and analogue Ranitidine

Active substance: Ranitidine.
Indications: Treatment and prevention - peptic ulcer of the stomach and duodenum, NSAID gastropathy, heartburn (associated with hyperchlorhydria), hypersecretion gastric juice, symptomatic ulcers, stress ulcers of the gastrointestinal tract, erosive esophagitis, reflux esophagitis, Zollinger-Ellison syndrome, systemic mastocytosis, polyendocrine adenomatosis; dyspepsia, characterized by epigastric or retrosternal pain associated with eating or disturbing sleep, but not caused by the above conditions; treatment of bleeding from the upper gastrointestinal tract, prevention of relapses stomach bleeding V postoperative period; aspiration pneumonitis, rheumatoid arthritis.

Zyrtec and analogue Cetirinax

Active substance: cetirizine
Indications: seasonal and year-round allergic rhinitis and conjunctivitis (itching, sneezing, rhinorrhea, lacrimation, conjunctival hyperemia), urticaria (including chronic idiopathic urticaria), hay fever, allergic dermatitis, itchy skin, angioedema, atopic bronchial asthma(as part of complex therapy).

Zovirax and analog Acyclovir

Active substance: acyclovir.
Indications: Cream and ointment for external use - herpes simplex of the skin and mucous membranes, genital herpes (primary and recurrent); localized herpes zoster ( auxiliary treatment). Eye ointment - herpetic keratitis.

Immunal and analogue Echinacea

Active substance: Echinacea purpurea extract.
Indications: Immunodeficiency states (including against the background of mental and physical fatigue), manifested by acute infectious diseases: colds, flu, infectious diseases inflammatory diseases nasopharynx and oral cavity, recurrent infections of the respiratory and urinary tract). Secondary immunodeficiency states after antibiotic therapy, cytostatic, immunosuppressive and radiation therapy.

Imodium and analogue Loperamide

Active substance: loperamide
Indications: diarrhea (acute and chronic of various origins: allergic, emotional, medicinal, radiation; when changing the diet and quality composition food, in case of metabolic and absorption disorders). Regulation of bowel movements in patients with ileostomy. As an auxiliary drug - diarrhea of infectious origin.

Iodomarin and analog Potassium iodide

Active substance: potassium iodide
Indications: Endemic goiter. Prevention of diseases caused by iodine deficiency ( endemic goiter, diffuse euthyroid goiter, during pregnancy, condition after resection of goiter).

Cavinton and analog Vinpocetine

Active substance: Vinpocetine.
Indications: spicy and chronic disorder cerebral circulation (transient ischemia, progressive stroke, completed stroke, post-stroke condition). Neurological and mental disorders in patients with cerebrovascular insufficiency (memory impairment; dizziness; aphasia, apraxia, movement disorders, headache).

Klacid and analogue Clarithromycin

Active substance: clarithromycin.
Indications: Antibiotic. Bacterial infections caused by sensitive microorganisms: upper respiratory tract infections (laryngitis, pharyngitis, tonsillitis, sinusitis), lower sections respiratory tract (bronchitis, pneumonia, atypical pneumonia), skin and soft tissues (folliculitis, furunculosis, impetigo, wound infection), otitis media; peptic ulcer of the stomach and duodenum, mycobacteriosis, chlamydia.

Claritin and analogue Loragexal

Active substance: Loratadine.
Indications:

Xenical and analogue Orsoten

Active substance: orlistat.
Indications: Obesity (if only dietary measures led to a decrease in body weight of at least 2.5 kg in 4 weeks). The action of the drug is based on blocking the work of lipase enzymes, which break down fats to a level where the body can absorb them.

Lazolvan and analogue Ambroxol

Active substance: ambroxol.
Indications: A mucolytic agent that stimulates the prenatal development of the lungs (increases the synthesis and secretion of surfactant and blocks its breakdown). Has secretomotor, secretolytic and expectorant effects; stimulates the serous cells of the glands of the bronchial mucosa, increases the content of mucous secretion and the release of surfactant in the alveoli and bronchi; normalizes the disturbed ratio of serous and mucous components of sputum. By activating hydrolyzing enzymes and enhancing the release of lysosomes from Clark cells, it reduces the viscosity of sputum. Increases motor activity ciliated epithelium, increases mucociliary transport.

Lamisil and analogue Terbinafine

Active substance: terbinafine
Indications: Fungal diseases of the skin and nails (for onychomycosis do not use dosage forms for local application), caused by sensitive pathogens (trichophytosis, microsporia, epidermophytosis, rubrophytosis, candidiasis of the skin and mucous membranes); pityriasis versicolor(only dosage forms for topical use).

Lyoton-1000 and analogue Heparin-acri gel 1000

Active substance: heparin sodium.
Indications: Prevention and treatment of thrombophlebitis of the superficial veins, post-injection and post-infusion phlebitis, hemorrhoids (including postpartum), elephantiasis, superficial periphlebitis, lymphangitis, superficial mastitis, localized infiltrates and swelling, injuries and bruises (including muscle tissue, tendons, joints), subcutaneous hematoma.

Lomilan and analogue Loragexal

Active substance: Loratadine.
Indications: Allergic rhinitis (seasonal and year-round), conjunctivitis, hay fever, urticaria (including chronic idiopathic), angioedema, pruritic dermatosis; pseudo-allergic reactions caused by the release of histamine; allergic reactions to insect bites.

Maxidex and analogue Dexamethasone

Active substance: dexamethasone.
Indications: Conjunctivitis (non-purulent and allergic), keratitis, keratoconjunctivitis (without damage to the epithelium), blepharitis, scleritis, episcleritis, retinitis, iritis, iridocyclitis and other uveitis of various origins, blepharoconjunctivitis, optic neuritis, retrobulbar neuritis, superficial corneal injuries of various etiologies (after complete epithelization of the cornea), prevention of inflammation after surgery, sympathetic ophthalmia. Allergic and inflammatory diseases (including microbial) of the ears: otitis media.

Mezim and analogue Pancreatin

Active substance: Pancreatin.
Indications: Replacement therapy for exocrine pancreatic insufficiency: chronic pancreatitis, pancreatectomy, condition after irradiation, dyspepsia, cystic fibrosis; flatulence, diarrhea of non-infectious origin. Impaired digestion of food (condition after resection of the stomach and small intestine); to improve food digestion in persons with normal gastrointestinal function in case of errors in nutrition (eating fatty foods, large quantity food, irregular diet) and in case of chewing dysfunction, sedentary life, long-term immobilization.

My comment! As for this analogue, according to my observations and the reviews of people who underwent therapy with mezim, the results are excellent. But pancreatin, alas, does not provide such a clear improvement.

Midriacil and analogue Tropicamide

Active substance: tropicamide
Indications: diagnostics in ophthalmology (examination of the fundus, determination of refraction by skiascopy), inflammatory processes and adhesions in the chambers of the eye. Drug addicts use it to enhance the effects of heroin and opiates.

Miramistin and analogue Chlorhexidine

Active substance: in the first case - miramistin, in the second - chlorhexidine.
Indications: Antiseptics, as a therapeutic and prophylactic agent for various infections, for antiseptic treatment and disinfection, as well as for the prevention of sexually transmitted infections.

Movalis and Meloxicam analogue

Active substance: meloxicam.
Indications: rheumatoid arthritis; osteoarthritis; ankylosing spondylitis (Bechterew's disease) and other inflammatory and degenerative diseases joints, accompanied by pain.

Neuromultivit and analogue Pentovit

Active substance: thiamine chloride (B1), pyridoxine hydrochloride (B6), cyanocobalamin (B12).
Indications: Vitamins. Polyneuropathy; neuritis; neuralgia; trigeminal neuralgia; radicular syndrome caused by degenerative changes in the spine; sciatica; lumbago;plexitis; intercostal neuralgia; facial nerve paresis.

No-spa and analogue Drotaverine

Active substance: drotaverine
Indications: Prevention and treatment: smooth muscle spasm internal organs (renal colic, biliary colic, intestinal colic, dyskinesia of the biliary tract and gallbladder of the hyperkinetic type, cholecystitis, postcholecystectomy syndrome); pyelitis; spastic constipation, spastic colitis, proctitis, tenesmus; pylorospasm, gastroduodenitis, peptic ulcer of the stomach and duodenum. Endarteritis, spasm of peripheral, cerebral and coronary arteries. Algodismenorrhea, threatened miscarriage, threatening premature birth; spasm of the uterine pharynx during childbirth, prolonged opening of the pharynx, postpartum contractions. When conducting some instrumental studies, cholecystography.

Normodipine and analogue Amlodipine

Active substance: amlodipine.
Indications: arterial hypertension, exertional angina, vasospastic angina, silent myocardial ischemia, decompensated CHF (as an auxiliary therapy).

Nurofen and analogue Ibuprofen

Active substance: ibuprofen.
Indications: Pain syndrome: myalgia, arthralgia, ossalgia, arthritis, radiculitis, migraine, headache (including menstrual syndrome) and toothache, at oncological diseases, neuralgia, tendinitis, tendovaginitis, bursitis, neuralgic amyotrophy (Personage-Turner disease), post-traumatic and postoperative pain syndrome accompanied by inflammation.

Omez and analogue Omeprazole

Active substance: omeprazole
Indications:– peptic ulcer of the stomach and duodenum (including those resistant to treatment with other antiulcer drugs); – reflux esophagitis; – erosive and ulcerative lesions of the stomach and duodenum associated with taking NSAIDs; – peptic ulcers caused by Helicobacter pylori (in combination with antibacterial drugs); – Zollinger-Ellison syndrome; – prevention of acid aspiration (Mendelssohn syndrome).

Panangin and analogue of Asparkam

Active substance: potassium and magnesium aspartate.
Indications: hypokalemia and hypomagnesemia (including those arising from vomiting, diarrhea; therapy with saluretics, corticosteroids and laxatives), accompanied by arrhythmias (including paroxysmal supraventricular tachycardia, atrial and ventricular extrasystole) against the background of digitalis intoxication, heart failure or heart attack myocardium.

Pantogam and analogue Pantocalcin

Active substance: hopantenic acid.
Indications: Cerebrovascular insufficiency caused by atherosclerotic changes in cerebral vessels, senile dementia ( initial forms), residual organic brain lesions in individuals mature age and the elderly, cerebral organic failure in patients with schizophrenia, residual effects past neuroinfections, post-vaccination encephalitis, TBI (as part of complex therapy).

Panadol and analogue Paracetamol

Active substance: paracetamol.
Indications: Feverish syndrome due to infectious diseases; pain syndrome (mild and moderate severity): arthralgia, myalgia, neuralgia, migraine, toothache and headache, algodismenorrhea.

Preductal MV and analogue Trimetazidine MV

Active substance: Trimetazidine. MV—trimetazidine modified-release tablets.
Indications: Coronary heart disease: prevention of angina attacks (in complex therapy); treatment of cochleo-vestibular disorders of ischemic nature (including dizziness, tinnitus, hearing impairment); Cochleo-vestibular disorders of ischemic nature (tinnitus, hearing impairment), chorioretinal vascular disorders with an ischemic component.

Rinonorm and analogue Rinostop

Active substance: xylometazoline.
Indications: Acute allergic rhinitis, acute respiratory infections with symptoms of rhinitis, sinusitis, hay fever; otitis media (to reduce swelling of the nasopharyngeal mucosa). Preparing the patient for diagnostic manipulations in the nasal passages.

Sumamed and analogue Azithromycin

Active substance: azithromycin.
Indications:

Taufon and analogue Taurine

Active substance: Taurine.
Indications: Dystrophic lesions retina eyes, incl. hereditary taperetinal abiotrophies; corneal dystrophy; senile, diabetic, traumatic and radiation cataracts; corneal injuries (as a stimulator of reparative processes).

Trental and analogue Pentoxifylline

Active substance: pentoxifylline.
Indications: Violations peripheral circulation, Raynaud's disease, tissue trophic disorders; cerebrovascular accidents: ischemic and post-apoplectic conditions; cerebral atherosclerosis(dizziness, headache, memory impairment, sleep disturbances), discirculatory encephalopathy, viral neuroinfection; IHD, condition after suffered a heart attack myocardium; acute disorders blood circulation in the retina and choroid eyes; otosclerosis, degenerative changes against the background of pathology of the vessels of the inner ear with gradual decline hearing; COPD, bronchial asthma; impotence of vascular origin.

Trichopolum and analogue Metronidazole

Active substance: Metronidazole.
Indications: Antibiotic. Protozoal infections: extraintestinal amebiasis, including amoebic liver abscess, intestinal amebiasis, trichomoniasis, giardiasis, balantidiasis, giardiasis, cutaneous leishmaniasis, trichomonas vaginitis, trichomonas urethritis. Infections caused by Bacteroides: infections of bones and joints, infections of the central nervous system, incl. meningitis, brain abscess, bacterial endocarditis, pneumonia, empyema and lung abscess, sepsis. Infections caused by Clostridium spp., Peptococcus and Peptostreptococcus species: abdominal infections (peritonitis, liver abscess), pelvic infections (endometritis, abscess fallopian tubes and ovaries, infections of the vaginal vault). Pseudomembranous colitis (associated with antibiotic use). Gastritis or duodenal ulcer associated with Helicobacter pylori.

Triderm and analog Akriderm GK

Active substance: Gentamicin + Betamethasone + Clotrimazole.
Indications: Simple and allergic dermatitis (especially complicated by secondary infection), atopic dermatitis (including diffuse neurodermatitis), limited neurodermatitis, eczema, ringworm (dermatophytosis, candidiasis, pityriasis versicolor), especially when localized in the groin area and large folds skin; simple chronic lichen (limited neurodermatitis).

Troxevasin and analogue Troxerutin

Active substance: troxerutin.
Indications: Varicose veins veins, chronic venous insufficiency with such manifestations as static heaviness in the legs, leg ulcers, trophic skin lesions, superficial thrombophlebitis, periphlebitis, phlebothrombosis, leg ulcers, dermatitis, hemorrhoids, post-thrombotic syndrome, diabetic microangiopathy, retinopathy, hemorrhagic diathesis.

Ultop and analogue Omeprazole

Ursofalk and analog Ursosan

Active substance: Ursodeoxycholic acid.
Indications: uncomplicated cholelithiasis (dissolution of cholesterol gallstones V gallbladder, if it is impossible to remove them surgically or endoscopic methods), chronic opisthorchiasis, primary biliary cirrhosis, primary sclerosing cholangitis, chronic active hepatitis, chronic autoimmune hepatitis ( atypical forms), non-alcoholic steatohepatitis, acute and chronic viral hepatitis, toxic liver damage (alcohol, drugs), atresia of the intrahepatic biliary tract, cholestasis with parenteral nutrition, biliary reflux esophagitis, biliary reflux gastritis, biliary dyskinesia, alcoholic hepatosis, acute hepatitis, chronic active hepatitis with cholestatic syndrome, liver pathology background of cystic fibrosis, congenital atresia of the bile duct, biliary dyspeptic syndrome(with cholecystopathy and biliary dyskinesia), cholestasis in newborns associated with complete parenteral nutrition. Prevention of liver damage when used hormonal contraceptives and cytostatics, prevention of gallstone formation in obese patients during quick loss body weight.

Fastum-gel and analog Ketoprofen

Active substance: ketoprofen.
Indications: Gel, cream: acute and chronic inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, spondyloarthritis, arthrosis, osteochondrosis); injuries of the musculoskeletal system (including sports), sprains, ruptures of ligaments and tendons, tendinitis, bruise of muscles and ligaments, edema, phlebitis, lymphangitis, inflammatory processes of the skin. Rinse solution: inflammatory diseases of the oral cavity and pharynx (angina, pharyngitis, stomatitis, glossitis, gingivitis, periodontitis, periodontal disease, etc.).

Finlepsin and analog Carbamazepine

Active substance: carbamazepine.
Indications: Epilepsy (excluding absence seizures, myoclonic or flaccid seizures) - partial seizures with complex and simple symptoms, primary and secondary generalized forms of seizures with tonic-clonic seizures, mixed forms of seizures (monotherapy or in combination with other anticonvulsants). Idiopathic trigeminal neuralgia, trigeminal neuralgia in multiple sclerosis (typical and atypical), idiopathic glossopharyngeal neuralgia. Phase leaking affective disorders(including bipolar) prevention of exacerbations, weakening of clinical manifestations during exacerbation. Syndrome alcohol withdrawal(anxiety, convulsions, hyperexcitability, sleep disturbances). Diabetic neuropathy with pain syndrome. Diabetes insipidus of central origin.

Flucostat and analogue Fluknazol

Active substance: fluconazole.
Indications: Systemic lesions caused by Cryptococcus fungi, including meningitis, sepsis, lung and skin infections. Generalized candidiasis: candidemia, disseminated candidiasis. Genital candidiasis: vaginal (acute and recurrent), balanitis. Prevention of fungal infections in patients with malignant tumors during chemotherapy or radiation therapy. Skin mycoses: feet, body, groin area, onychomycosis, pityriasis versicolor, skin candidal infections. Deep endemic mycoses (coccidioidosis, sporotrichosis and histoplasmosis) in patients with normal immunity.

Furamag and analogue Furagin

Active substance: furazidin.
Indications: infectious and inflammatory diseases: purulent wounds, cystitis, urethritis, pyelonephritis, purulent arthritis; infections of female genital organs; conjunctivitis, keratitis; burns; prevention of infections during urological operations, cystoscopy, catheterization. For washing cavities: peritonitis, pleural empyema.

Chemomycin and analogue Azithromycin

Active substance: azithromycin.
Indications: Antibiotic. Infections of the upper respiratory tract and ENT organs caused by sensitive pathogens: pharyngitis, tonsillitis, laryngitis, sinusitis, otitis media; scarlet fever; lower respiratory tract infections: pneumonia, bronchitis; infections of the skin and soft tissues: erysipelas, impetigo, secondary infected dermatoses; urinary tract infections: gonorrheal and non-gonorrheal urethritis, cervicitis, gastric and duodenal ulcers associated with Helicobacter pylori.

Enap and analogue Enalapril

Active substance: knew adj.
Indications: arterial hypertension (symptomatic, renovascular, including with scleroderma, etc.), CHF I-III stages; prevention of coronary ischemia in patients with LV dysfunction, asymptomatic LV dysfunction.

Ersefuril and analogue Furazolidone

Active substance: nifuroxazide in the first case and furazolidone in the second.
Indications: Diarrhea of infectious origin, dysentery, paratyphoid fever, giardiasis, food toxic infections.

What are some tricks in pharmacies?

I myself go to pharmacies exclusively to familiarize myself with the assortment of herbs. So, I come specifically to write this note to the pharmacy. I talk with our pharmacist. For example, I say, what drops are there for a runny nose?

She gives me a list from 100 rubles to the top. Well, based on his acquaintance, he also gives out information that, they say, there are, of course, cheaper ones, for 20 rubles. These are Xylen and Rinostop. Moreover, the active substance in them is the same. This is Xylometazoline.

Why they sell expensive ones, but don’t sell cheap ones is clear and without comment. So it’s important to be able to understand this sea of medications if you already use them.

The domestic pharmaceutical market offers a wide variety of drugs, but at the same time, most of them are very expensive. As an affordable alternative, many people prefer to choose Russian analogues of imported drugs, the list and compliance of which can be obtained from the attending physician or pharmacist at the pharmacy.

Painkillers and antispasmodics

Painkillers (analgesics) are intended to relieve pain syndromes of various origins. In general, analgesics are divided into 2 groups:

Non-narcotic drugs containing acetylsalicylic acid, analgin, paracetamol, mefinamic acid, piroxicam, ibuprofen, dimexide, etc.
Narcotic drugs that are prescribed in the most extreme and serious cases, for example, morphine, promedol, fentanyl, etc.

Antispasmodics (antispasmodics, antispasmodics) are intended to relieve spasms of blood vessels, smooth muscles of internal organs, for example, the gastrointestinal tract, urinary and biliary tract, and female reproductive system.

Cardiac and hypotensive

Cardiac drugs combine several groups of drugs to improve ischemic and cerebral circulation, normalize heart rate, increasing the content and transport of oxygen to the heart.

Antihypertensive (antihypertensive) drugs are intended to reduce blood pressure. The required effect can be achieved by different principles actions of drugs:

decreased tone of the sympathetic nervous system;
suppression of renin production (a component of the blood pressure regulation system);
vasodilation;
increasing urine output (diuretics).

Antibacterial and antiviral

Antibacterial drugs (antibiotics) - drugs that suppress growth harmful microorganisms or causing their death.

Antiviral drugs are medications that are used to treat viral diseases of various origins. They are often used to prevent viral diseases and to increase the body’s immunity in complex therapy.

Anti-inflammatory and antipyretic

Nonsteroidal anti-inflammatory drugs (NSAIDs, NSAIDs) have an anti-inflammatory effect, to which antipyretic and analgesic effects are also added.

Antidiarrheal

Diarrhea (stomach upset) is common symptom various diseases Gastrointestinal tract, other internal organs, intoxications. Antidiarrheal drugs reduce intestinal motility, increase sphincter tone. This group also includes eubiotics (enzymes and bacteria that regulate the microflora of the gastrointestinal tract) and adsorbents (cleaning the gastrointestinal tract from toxins and allergens).

Name	Active substance	Russian analogue
Imodium	Loperamide	Vero-Loperamide Diara Loperamide
Linux	Lactic acid and bifidobacteria	Bifidumbacterin Bifinorm Lactobacterin Lactonorm
Nifuroxazide	Nifuroxazide	Ecofuril
Smecta	Dioctahedral smectite	Diosmectite Neosmectin
Sorbex	Activated carbon	Activated carbon

Antiulcer

Action antiulcer drugs is aimed at eliminating ulcerative manifestations on the mucous surface of the stomach and duodenum. They reduce excessive secretion of gastric secretions, reduce the activity of pepsin (the main enzyme of gastric juice), destroy Helicobacter in the gastrointestinal tract, and normalize upper motility digestive tract.

Antiallergic

Allergy medications (antihistamines) block histamine receptors in the body, a neurotransmitter that affects Airways, skin, gastrointestinal tract, blood vessels, smooth muscles and causes an allergic reaction.

Inhalation drugs and cough suppressants

Inhalation is a method of introducing drugs into the body by inhaling steam, gas or smoke. To carry it out, nebulizer devices (inhalers, nebulizers) are used, which are filled with gaseous, liquid or volatile substances.

Mucolytic drugs are cough medications that discharge mucus in the lungs and facilitate its elimination, reducing the inflammatory process in the respiratory tract.

Calming

Sedatives (sedatives, psycholeptics) are a group of medications that cause calm or reduce emotional stress without a hypnotic effect, and at the same time facilitate the process of falling asleep and improve the quality of sleep.

Preparations for external use

The group of medicines for external (local) use combines a huge number of drugs in the form of ointments, gels, creams, solutions, powders, etc. Depending on the composition, they have antibacterial, disinfectant, analgesic, anti-inflammatory, antihistamine and other effects.

Best articles
2015

They say there are no simple times. But how little consolation this is when you are faced with a total rise in price for everything! The basis of today's home economy is saving. We constantly have to look for “something similar, but cheaper.” Are such substitutions correct and how not to make money? oxygen deficiency when trying to tighten your belts?

"Disservice" of the Internet

The most popular and almost bottomless storehouse of information is, of course, the Internet. We fearlessly plunge into the World Wide Web, naively believing that the mind will help distinguish lies from truth. But, alas, this is not always the case.

Millions of Russian citizens, in an effort to save money, study lists of domestic analogues of expensive imported drugs that flood the Internet. Tomorrow they will go to the pharmacy and with undisguised pleasure will buy a cheap domestic “substitute” instead of the original drug. And then the story can have a different continuation, and it depends on the anonymous person with an unknown education who posted the information, and on His Majesty Chance.

Behind this careless trust lies an invisible tragedy. When I, a pharmacist with many years of experience, open such a “list of substitutes,” I can hardly contain my emotions. Unnamed authors strongly advise replacing the Mercedes with a VAZ, arguing that domestic cars also have four wheels. And sometimes they offer a scooter with the sauce of a car!

My pharmaceutical consciousness is boiling, having noticed in the list of “analogues” several pairs of completely different drugs. For example, miramistin is not chlorhexidine, and ersefuril has only one relationship to furazolidone: both drugs belong to the nitrofuran group. And this is just a drop in the sea. Moreover, even replacements that are quite correct at first glance may be far from harmless.

Original drug and analogue

An original medicine is a drug that was first synthesized by the manufacturer. When buying an original, or, as pharmacists often say, a brand drug, we pay for many years of development of the drug substance, for registration, and so on. The manufacturer includes all these huge costs in the price, so original drugs are a priori much more expensive than generics (from the English generic), or analogues.

Manufacturers of analogues only synthesize the substance according to a well-known algorithm and prepare it from dosage form and pack. Their costs are minimal, and this has the most favorable effect on the price of the final product. Ideally, analogues should correspond to the brand drug in all respects, including effectiveness. But in reality?

The medicinal substance is the basis of the drug, its “core”. The effectiveness of the future drug depends on how well it is synthesized and how well all technological requirements are met. In addition, the medicine contains a lot excipients, which also affect bioavailability, absorption and other indicators, and therefore the final result.

In order to “comb” all manufacturers with one quality brush, in 1968, with the participation of the WHO, uniform standards for the production of drugs and dietary supplements, GMP (Good manufacturing practice), were adopted. The GMP system regulates all aspects of the production of medicines: from starting materials, the condition of premises and equipment to personal hygiene and personnel training. By the way, not everyone has switched to GMP Russian enterprises, and this gives another reason for thought.

But even if all requirements and standards are met, the generic may differ from the original. In 2000, American scientists published data from an independent study. After comparing the properties of the original drug Klacid and forty of its generics produced in 13 countries, scientists came to a disappointing conclusion. Not a single analogue has been recognized as equivalent to the original! And this despite the fact that all drugs were produced in accordance with GMP requirements.

We save correctly

And yet experience shows what to cook good fish soup You can make it from cheap fish if you follow all the cooking rules. First, you need to decisively click the mouse to remove sites with unfortunate lists from your bookmarks. Well, fluconazole of unknown production cannot work in the same way as the famous Diflucan, purified, standardized and verified to thousandths of a milligram!

Do not expect the same effect that the unique enzyme Creon gives from domestic pancreatin. Yes, they have the same active ingredients - the Internet did not deceive us on this. But making an enzyme that will not be destroyed in the stomach and intestines, but will be absorbed and, most importantly, will begin to act like its own, is a whole art. And so far it is not available to domestic enterprises.

Of course, an engineer or teacher cannot know pharmaceutical intricacies, and should not. Moreover, even the pharmacist has no right to interfere with prescriptions and change one drug to another. But a doctor who treats hundreds of patients clearly sees how the original and the generic work, and knows exactly the difference between Voltaren and diclofenac. Therefore, the decision to replace should only be made by the doctor.

Don't feel embarrassed and tell your doctor if you can't afford an expensive brand-name drug. The choice of drugs on the modern market allows you to replace the original drug with a high-quality and more economical analogue that is not inferior to its ancestor in effectiveness. And be sure to close sites that offer to exchange awl for soap and never open them again.

Marina Pozdeeva

Photo by Alina Trout