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Most people, not just women, are familiar with candidiasis. Its symptoms are eloquent and unpleasant, and the causes of its appearance are varied and numerous. Modern pharmacology offers a wide range of drugs used to treat this fungal infection. Pimafucin is often prescribed for thrush, since the drug quickly relieves symptoms and prevents the proliferation of Candida fungi.

Pimafucin – medicine, belonging to the group of fungal antibiotics and having a fungicidal effect. Considered safe for everyone age groups patients, pregnant and lactating women.

The drug is available in several forms, which determine its composition:

Tablets in a coating resistant to gastric juice and soluble in the intestines. Packaging: bottle, each containing 20 tablets.
Intervaginal suppositories. Packaging – contour, cell-free, 3 pieces each, 2 packs in a box.
Cream for topical use on affected areas of the skin. Comes in a 30 ml tube.

In all forms, the active substance is natamycin - it is the one that has the antifungal effect.

potato starch;
polyvinylpyrrolidone;
magnesium salt of stearic acid;
lactose;
sucrose;
gelatin;
methyl p-hydroxybenzoate;
calcium carbonate;
cellulose acetate phthalate;
white beeswax;
glyceryl triacetate;
titanium oxide.

Consist of these excipients:

cetyl alcohol;
hard fat;
sorbitol;
polysorbitol;
sodium bicarbonate;
carboxylic acid.

In addition to natamycin, it contains:

decyloleate;
wax;
cetearyl alcohol;
sodium dodecyl sulfate;
preservative E218;
propyl parahydroxybenzoate;
propanediol;
water.

The instructions for use indicate that the product must be stored at temperature conditions no higher than 25 degrees, away from children. The shelf life is 4 years, after which Pimafucin cannot be used for treatment.

How does Pimafucin work?

The active substance of the drug penetrates fungal cells through their membranes and destroys them. The most sensitive to natamycin are fungi of the genus Candida, the pathological reproduction of which leads to thrush.

According to the instructions, Pimafucin does not have any effect on the vital activity of gram-positive or gram-negative microorganisms.

Natamycin - its action

Natamycin does not have a systemic effect, since it is almost not absorbed from gastrointestinal tract, healthy skin and mucous membranes. Enteric-coated tablets release the active ingredients while they are already in the intestines. Progressive biochemical research confirm the absence of the active substance in the blood and other body fluids of people undergoing Pimafucin therapy.

Pimafucin suppositories turn into foam under the influence of body temperature, which spreads evenly along the walls of the vagina.

The effectiveness of treatment with Pimafucin is expressed in:

relieving the main symptoms of thrush literally from the first use: itching and heavy discharge;
relieving swelling in the vagina;
destruction of fungal cells and spores;
in pregnant women - improvement general condition women and fetus, decreased tone and the likelihood of premature birth.

When is the drug prescribed?

Instructions for use of the drug Pimafucin contain a list of fungal infections different organs body, which are considered indications for using the product.

Diseases for which it is advisable to use tablets:

Candidiasis of mucous surfaces oral cavity in acute pseudomembranous and atrophic form, which arose against the background of weakened immunity, including from the use of medications.
Otomycosis or otitis media of fungal etiology, complicated by the proliferation of pathogenic fungi.
Candidiasis of the skin and nail plates.
Inflammatory processes on the glans penis, provoked by the proliferation of Candida fungi.
Vulvovaginal candidiasis, vulvitis, balanoposthitis.
As the main and aid ringworm.

Tablets for the treatment of skin can be used alone, with Pimafucin cream or in combination with other drugs, for example, Griseofulvin.

According to the instructions, diseases of the genital organs are treated with the help of suppositories:

vaginitis, vulvovaginitis, vulvitis, caused by Candida fungi;
sometimes - to eliminate pathological discharge and vaginal itching not caused by fungi.

The cream is used for the same indications as the tablets and for the treatment of ulcers that occur in people with diabetes.

According to clinical studies, Pimafucin was effective in all cases of use. Maximum positive results were achieved in the treatment of vaginitis caused by fungi of the genus Candida.

Use during pregnancy and lactation

The instructions for use indicate that women during pregnancy and breastfeeding are allowed to be treated with Pimafucin for thrush.

Some experts argue that the use of this remedy is necessary in extreme cases, since it is not effective and can aggravate the course of thrush. But such conclusions are based on isolated cases, and the medicine is the most popular in the fight against the disease. Its use is allowed in all three trimesters, without harm to the health of the mother and fetus.

Dosage of the drug according to the instructions

Only a doctor prescribes the drug and its dosage, after comprehensive examination patient. The following regimens for use of the drug recommended in the instructions are considered standard:

The dosage of oral tablets is 4 tablets per day for adults, and 2 for children, throughout the week.
Pimafucin suppositories are administered 1 per day for 3–6 days. If candidiasis is severe, then treatment with suppositories is supplemented with tablets.
Local application of the cream is prescribed individually, depending on the brightness and severity of symptoms. On average - from 1 to 4 times a day. If necessary, intensify treatment with tablets.

Method of application indicated in the instructions

Intervaginal administration of suppositories must be carried out at night, in a lying position, so that the product does not leak out, and its effectiveness does not decrease due to its smaller amount.

Dermatomycosis most often affects fat people, and foci of inflammation are usually located in the folds, between the phalanges of the fingers, in groin area and under the mammary glands.

Ulcers in people with diabetes most often form on the feet. When using the cream, it is recommended to continue therapy for another 3-4 days after the symptoms disappear. Otomycosis requires the use of cream up to 4 times a day. The ear canal is first cleaned, and after lubrication, it is closed with a cotton pad.

On critical days, treatment with Pimafucin is interrupted. If possible, therapy should be started after menstruation.

It is recommended to examine your sexual partner for the presence of a fungal infection. Men are its carriers, but their candidiasis is not so pronounced and is often asymptomatic. But if their thrush is not cured, then the woman will soon have a relapse with a 95% probability.

Sexual intercourse during thrush therapy cannot be ruled out, but barrier contraceptives must be used.

When should you not use Pimafucin?

According to the instructions for use, the drug Pimafucin is contraindicated in the following cases:

Individual intolerance or increased sensitivity to the components of the drug.
Patients with intolerance to lactose, fructose and other saccharides contained in the drug.

The drug is used to treat children, starting from newborn age.

The compatibility of the drug with other medications has not been fully studied.

Side effects

Side effects from the use of Pimafucin are extremely rare, and their list given in the instructions is not numerous:

At internal reception tablets in the first days of therapy, the patient’s condition may be accompanied by nausea and stool upset.
Topical application can cause itching and burning of the skin of the genital organs due to cetyl alcohol in the composition of the suppositories.

The drug does not provoke allergic reactions; so far, not a single case has been recorded.

Overdose

Cases of overdose with Pimafucin have not been identified or described, as indicated in the instructions for use of the product.

Drug analogues

One of the few disadvantages of the drug is its high price. More accessible analogues are:

Irunin tablets are not much different from Pimafucin in price, are very effective and have virtually no contraindications. The active ingredient is itraconazole.
Intervaginal suppositories that have the same active substance (Ecofucin, Primafungin).

The new drug Livarol is considered effective, but differs in composition; the main antifungal effect is ketoconazole. Livarol is prohibited for the treatment of thrush in women during the first trimester of pregnancy.

A drug	Photo	Price
		from 290 rub.
		from 364 rub.
		from 152 rub.
		from 184 rub.
		from 496 rub.
		from 184 rub.

Analogues include creams - antifungal antibiotics local use:

Primafungin - available in 20 mg tubes, the active substance is the same as Pimafucin.
Nystatin ointment - available in 30 mg tubes, the active substance is nystatin.

In addition to Nystatin ointment, release forms in tablets and suppositories are known. Oral use The drug is contraindicated for children and pregnant women, according to the instructions.

In addition to those listed, accessible analogue is Fluconazole, the price of which starts from 20 rubles. It is available in the form of tablets, capsules and solution for infusion. The active ingredient is fluconazole. Unlike Pimafucin, according to the instructions, it is prohibited to be used to treat children under one year of age, and it has much larger list contraindications.

Pimafucin is recognized by many gynecologists as the most effective and safe drug for the treatment of thrush and other fungal diseases. Diversity dosage forms and the simplicity of the instructions makes it convenient to use.

Video: Thrush and how to deal with it

Active substance(it is also international generic name): Natamycin.

Dosage forms:

pimafucin suppositories, tablets, pimafucin cream

Pharmacological action and pharmacokinetics of Pimafucin:

Antifungal polyene antibiotic of the macrolide group, which has a wide spectrum of action. The drug is active against yeast (Torulopsis, Rhoduturola), yeast-like fungi (Candida albicans), dermatomycetes (Trichophyton, Microsporum, Epidermophyton), other pathogenic fungi (Aspergillus, Penicillium), as well as Trichomonas.

Has a fungicidal effect. Pimafucin binds sterols of cell membranes, disrupting their integrity and functions, which leads to the death of microorganisms. Dermatophytes are less sensitive to natamycin, but resistance to natamycin in clinical practice does not occur. Not absorbed from the gastrointestinal tract, skin and mucous membranes.

Use of Pimafucin, for which diseases is it used in therapy?:

Prescribed for fungal infections of the skin and mucous membranes, including acute pseudomembranous and atrophic candidiasis after therapy with antibiotics, glucocorticosteroids and cytostatics, genital candidiasis, otomycosis, candidiasis of the skin, nails and intestines, vaginitis, vulvitis, dermatomycosis, etc. Also used for trichomoniasis. Use internally and topically.

Clearer gradation according to drug forms:

pimafucin tablets:

treatment and prevention of non-invasive intestinal candidiasis (including after taking antibiotics, cytostatics, corticosteroids).

pimafucin cream:

skin and mucous membrane infections caused by Candida fungi or other sensitive yeasts, yeast-like fungi or dermatophytes (including balanoposthitis, otomycosis).

pimafucin suppositories:

vulvovaginal candidiasis.

Pimafucin dosage regimen:

For vaginitis, vulvitis, vulvovaginitis, 100 mg (1 vaginal suppository) is prescribed for 6-9 days. The suppository is inserted into the vagina in a lying position, as deep as possible, 1 time/day at night. In case of persistent vaginitis caused by Candida albicans, the drug is additionally prescribed orally (1 tablet 4 times a day for 7-10 days) to sanitize the focus of candidal infection in the intestine. To treat candidiasis of the partner's genital organs, Pimafucin is used in the form of a cream.

For balanoposthitis, the cream is applied to the affected areas of the skin one or several times a day.

For intestinal candidiasis, adults are prescribed 100 mg (1 tablet) 4 times a day orally for an average of 1 week. Children are prescribed 100 mg (1 tablet) 2 times a day.

For dermatomycosis (including skin candidiasis, diaper rash in children), the cream is applied to the affected surface of the skin once or several times a day.

In case of otomycosis, the affected surface is lubricated with cream once or several times a day. Before using the drug, the ear is cleaned. After using the drug in ear canal Place a tampon made of natural material (cotton, wool).

The duration of the course of treatment is determined individually. After the symptoms of the disease disappear, it is recommended to continue treatment for several more days.

Pimafucin during pregnancy and lactation:

The drug can be used during pregnancy and lactation according to doctor's indications; in fact, it is one of the drugs of choice during pregnancy.

Side effects from the use of Pimafucin:

Possible nausea, diarrhea (occurring in the first days of taking the drug in tablet form and passing on its own during treatment), mild irritation, a burning sensation (when using cream, vaginal suppositories) are possible.

Contraindications for use:

Individual intolerance to the drug, porphyria

special instructions:

It is worth considering that under the influence of body temperature, vaginal suppositories quickly dissolve, forming a foamy mass, which contributes to uniform distribution active substance.

Pimafucin can be used as additional drug in the treatment of dermatomycosis with griseofulvin.

Cetyl alcohol, which is part of vaginal suppositories, can cause hypersensitivity reactions.

In case of chronic or recurrent infection local treatment can be supplemented by prescribing tablets and cream.

During menstruation, suppository therapy is interrupted.

However, it is recommended to conduct an examination of sexual partners and, if candidiasis is detected, to conduct a course of treatment with Pimafucin. Also during the treatment period you should use barrier means contraception.

During the period of using suppositories, there is no need to avoid sexual intercourse.

Pimafucin can be prescribed to newborns.

Drug interactions:

No interaction with other drugs has been described.

How best to store Pimafucin:

At a temperature of 15° to 25°C. The shelf life of vaginal suppositories is 2 years, tablets and cream are 4 years.

The description of the drug (pimafucin suppositories, cream, pimafucin tablets, etc.) is not intended self-treatment. The drug has contraindications and side effects. Consultation with a specialist is necessary.

Pimafucin is a modern polyene antibiotic belonging to the macrolide group. The medicine has a very wide spectrum of action. It has pronounced fungicidal properties, making it good for fungal infections. Most often, Pimafucin vaginal suppositories are prescribed to patients suffering from thrush in its various manifestations.

Table of contents: Active substance and release forms Pharmacological action Indications Scheme of use Possible side effects Who should not use Pimafucin? Pimafucin for pregnant and lactating women Interaction with other drugs Additionally Pimafucin analogues Storage rules and conditions for dispensing from pharmacies

Active active ingredient Pimafucin is a natamycin antibiotic substance.

The medicine is produced pharmaceutical companies in tablet form, as well as in the form of ointment, cream and vaginal suppositories.

Each Pimafucin suppository contains 100 mg of an antifungal substance.

Yellow or brownish candles are supplied in individual foil packages. There are 3 or 6 suppositories in a cardboard box.

Natamycin is able to react with sterols in the cell wall of yeast-like fungi, which leads to its destruction and, as a consequence, cell death.

This antibiotic is active against wide range pathogenic fungi. It is extremely effective against the causative agent of thrush ( vaginal candidiasis) – Candida albicans. Dermatophytes are also quite sensitive to Pimafucin.

At local application(in the form of suppositories) the antibiotic is not absorbed into the blood and, therefore, does not have a systemic effect.

Vaginal suppositories Pimafucin are prescribed for the following infectious and inflammatory diseases provoked by pathogenic fungal microflora:

vaginitis;
vulvitis;
vulvovaginitis.

The drug allows for correct use V as soon as possible get rid of the so-called "thrush".

For infectious and inflammatory diseases of the female organs reproductive system patients are prescribed 1 suppository per day. The product is intended for course therapy. Average duration The course lasts from 3 to 6 days (the timing is determined by the attending gynecologist).

It is advisable to continue antifungal therapy for several days after complete relief clinical signs diseases (itching, burning, pathological whitish discharge).

Pimafucin suppositories are used topically; they are inserted into the vagina as far as possible possible depth, having previously accepted horizontal position. The procedure is carried out once a day, in the evening before bedtime.

In case of persistent recurrent course of thrush, the drug must be additionally taken orally in the form of tablets (1 piece 4 times a day). The duration of the course varies from 10 to 20 days. Oral administration is necessary to destroy Candida fungi in the intestines, i.e., sanitize a chronic source of infection.

Note: At the same time, treatment is carried out for the sexual partner, who, if unprotected contacts inevitably becomes a carrier of a fungal infection. For the treatment of candidiasis in men, Pimafucin cream is used topically (1-3 times a day). The duration of therapy is determined in each clinical case strictly individually (taking into account possible development candidiasis balanoposthitis).

The vast majority of patients tolerate Pimafucin well.. In some cases (very rarely) there are light feeling burning sensation in the vagina and minor irritation of the mucous membranes due to the presence of an auxiliary ingredient such as cetyl alcohol in the suppositories. These side effects are not grounds for interrupting the course.

Pimafucin suppositories have virtually no contraindications for use. The drug is not prescribed only to those patients who have individual hypersensitivity to the active substance.

It is quite acceptable to use vaginal suppositories during pregnancy and breastfeeding baby. Since when local use there is no systemic absorption (absorption), the active component does not enter the blood and breast milk. Data obtained during clinical trials, have convincingly proven the absence negative influence antibiotic to the fetus.

Drug antagonism and other types of interaction of Pimafucin with others pharmacological agents has not been identified to date.

Under the influence of body temperature, intravaginally inserted suppositories quickly heat up, turning into a foamy substance. This promotes the most even distribution of the antibiotic in the area affected by Candida fungi.

It is advisable to interrupt the course of treatment during menstruation.

There is no need to abstain from sexual intercourse during therapy, but the partner must use a condom or undergo treatment at the same time Pimafucin.

The drug does not affect the reaction rate, so patients can drive a car and work with other potentially dangerous objects.

IN pharmacy chains You can purchase medications for topical use that contain the same active substance. These are Primafungin, Ecofucin and Natamycin.

For fungal vulvitis and vaginitis, you can also use the following suppositories:

Miconazole;
Betadine;
Polygynax;
Zalain;
Terzhinan;
Livarol;
Fluomizin.

You do not need a doctor's prescription to purchase this thrush medicine.

The shelf life of the drug is 2 years from the date of release (it is indicated on the packaging).

Keep away from children!

Plisov Vladimir, medical observer

Instructions for the use of pimafucin suppositories, description of the action of the drug, indications for the use of pimafucin suppositories, interactions with other medications, use of pimafucin (suppositories) during pregnancy. Instructions:

Pimafucin in cream

Pimafucin tablets

1 suppository contains: natamycin 100 mg.

1 suppositorydin kuramynda: 100 mg natamycin.

1 suppository contains: cetyl alcohol, solid fat, sorbitone trioleate, polysorbate 80, sodium bicarbonate, adipic acid.

1 suppositorydin kuramynda: cetyl alcohol, katty may, sorbitone trioleates, polysorbate 80, sodium bicarbonates, adipine kyshkyly.

vaginitis, vulvitis, vulvovaginitis.

mild irritation, burning sensation.

Married terken, kuydіru sіmi.

Vaginal suppositories quickly dissolve under the influence of body temperature, forming a foamy mass, which contributes to the uniform distribution of the active substance. In case of chronic or recurrent infection, local treatment can be supplemented with tablets and cream.

Ethanol, which is included in vaginal suppositories, can cause hypersensitivity reactions. During menstruation, suppository therapy is interrupted. During treatment with suppositories there is no need to avoid sexual intercourse. However, it is recommended to conduct an examination of sexual partners and, if candidiasis is detected, to conduct a course of treatment with Pimafucin. The use of barrier methods of contraception during treatment should also be considered.

Pregnancy and lactation

It is possible to use Pimafucin during pregnancy and lactation.

Features of the effect of the drug on the ability to drive a car or potentially dangerous mechanisms

Does not affect.

Please note that the suppository is at the same temperature as the temperature of the container, the mass of the product, the substance in the container of the breast. Sozylmaly nemes kaytalanatyn zhukpa zhagdayynda zhergiliktі emge kosymsha retina tablet men cream tagaiyyndaluy mumkіn.

Use a suppository for the preparation of ethanol, burn the seeds, and react for the first time. Etekkir kezinde suppositorymen emdeudi toktata turady. The suppository is in the right place. Alaida zhynystyk zhuptasyn tekseru, al candidoza zakymdanu anyktalgan zhagdaida Pimafucinmen emdeu kursin zhurgizu usynilady. Sonymen katar emdelu kezinde contraception bogegish adisterin paidalanuda and karastyrgan zhon.

Zhuktilik zhane lactation case

Pimafucin lactation zhane zhuktilik kezinde koldanyluy mumkin.

Darilik drug car nemes kauiptiligi zor mechanismderd baskar kabiletina aser etu erekshelikteri

Aser etpeidi.

Prescribe 1 suppository for 3-6 days. Suppositories are inserted into the vagina in a lying position, as deep as possible, 1 time/day. for the night. For persistent vulvovaginitis caused by Candida albicans, additional tablets are prescribed orally (1 tablet 4 times a day for 7-10 days). To treat candidiasis of the partner's genital organs, use Pimafucin in the form of a cream.

3-6 kun fights 1 suppository den tagayyndaydy. Suppositories during the process 1, press the press button, and then press the button again. Candida albicans Tuyndatkan vulvovaginitis uzak kaytpasa, tablet kalard (7-10 kun battles tauligine 4 ret 1 tablet kadan) іshke қајымша тағайындиди. If you want to eliminate candidiasis, use our cream turindegi pimafucindi paydalanada.

No drug interactions have been described.

Darilermen ozara arekettesui sipattalmagan.

Currently, no cases of overdose of the drug Pimafucin have been reported.

Kazirgi wherever Pimafucin drug artyk dosalanu zhagdaylary turaly khabarlanbagan.

Natamycin is a drug local action, is practically not absorbed through mucous membranes.

Natamycin is a gergillykti aseri bar drug, іѕ zүzіndе shyrishty kabyk arkyly sіnbeidі.

Antifungal polyene antibiotic with fungicidal action. Natamycin binds sterols of cell membranes, disrupting their integrity and functions, which leads to the death of microorganisms. Most pathogenic yeasts are sensitive to natamycin, especially Candida spp. Dermatophytes are less sensitive. Resistance to natamycin among yeasts is not found in clinical practice.

Fungicides aseri bar zenge karsy polyendi antibiotic. Natamycin zhasusha zhargakshalary steroldaryn, olardyn tutastygy men kyzmetin byzyp, baylanystyrady, bul microorganismderdin kyryluyn akeledi. Natamicinge koptegen pathogendi ashytky zenderi, asіrese Candida spp. season. Dermatophytterdin sesimtaldygy asdau. Klinikalyk tazhiribede ashytky zenderdin arasynda natamitsinge tozimdilik kezdespeydy.

3 suppositories are placed in a contour cell packaging made of polyvinyl chloride film. 1 blister pack along with instructions for medical use in the state and Russian languages are placed in a cardboard box.

3 suppositories are made of polyvinyl chloride and are used in the saline container. 1 pіshіndі ұяшықты қaptamadan medicinada qoldanyluy zhөnіndegі memlekettik zhane orys tіlderіndegі nуsқауліkpen bіrge cardboard pəshkege salynada.

Information on how to use Pimafucin suppositories can be obtained from your doctor or read in the instructions. Let's talk about this in more detail.

Thrush or candidiasis is one of the modern problems which causes discomfort, requires immediate treatment. Nowadays, there are a number of drugs aimed at treating candidiasis, including Pimafucin suppositories.

Pimafucin, available in the form of vaginal suppositories, has a yellow-brown color. color scheme, packed in sealed foil packaging, duplicating the configuration of the candle. The package contains up to 6 candles.

The active component of the drug is natamycin, a polyene antimycotic belonging to the group of macrolipids, combining the widest spectrum of action. Thrush microorganisms are most sensitive to the drug; therefore, the drug is used in the treatment of candidiasis.

The drug is indicated for the treatment of candidiasis, as well as a number of its varieties:

vulvoginitis;
vulvitis;
vaginitis.

Thrush, both female and male, appears during the period of low immune defense. Mushrooms of the Candida variety can be found on the mucous membranes of the human genitals during the development of the disease. With normal immunity, they do not lead to candidiasis. However, in case of hypothermia, stress, malfunction metabolic processes body and hormonal levels, during a period of decreased immune defense and under the influence of other provocateurs, microorganisms are capable of intensive reproduction, which leads to the occurrence of disease.

The drug Pimafucin is available in following forms: tablet, cream, vaginal suppositories.

The tablet form is suitable for the treatment of vaginal candidiasis. As you know, tablets are prescribed to prevent the development of candidiasis in the gastrointestinal tract or to restore intestinal microflora when using corticosteroid drugs, antibiotics and cytostatics.

The duration of therapy and the dosage of the drug for thrush depend on the doctor’s prescription and the results of the tests that the patient takes upon completion treatment course On average, treatment lasts 1 week.

Vaginal suppositories - effective remedy to cure thrush in women. They should be inserted into the vagina, 1 piece at a time. The course of treatment procedures lasts 10 days in combination with the tablet form of the drug; oral administration (4 tablets per day) is necessary to destroy microorganisms that have penetrated the intestinal flora.

The regimen for using the drug for thrush is standardized: 1 suppository per day, immediately before bedtime. It should not be wetted; the vaginal suppository is inserted in a lying position, as deep as possible. After the symptoms disappear, you need to continue healing procedures at least 3 days to avoid relapse. The average duration of the treatment course is 1 week.

In case of complications, the specialist prescribes tablets for the purpose of prophylaxis to prevent intestinal candidiasis or eliminate existing focal lesion Gastrointestinal tract. If the external genitalia are affected, you can treat with Pimafucin cream.

Men are recommended to use Pimafucin cream throughout the entire treatment course to prevent candidiasis and candidiasis in men. No need to pause intimate relationships, but no one canceled protection; barrier protection was recommended.

The following advantages of the drug are noted:

High sensitivity to active component natamycin, as well as additional components.
Can be taken during pregnancy and lactation.
The medicine does not penetrate the mother's bloodstream and does not have a negative effect on the fetus.
During menstruation, you should take Pimafucin in tablet form.

The product has a gentle effect on the body, there are no side effects. In exceptional cases, burning and mild degree irritation.

When the medicine is administered internally, the components do not enter the bloodstream and do not have a systemic effect on the body. No overdose situations were recorded.

Individual intolerance to the components of the drug is the only contraindication to the use of these suppositories.

Candles do not affect the control of vehicles and other mechanisms.

Sales are carried out without a prescription. Shelf life - 24 months, store the drug in a dark place at temperatures up to +25°C.

Attention! During critical days therapeutic treatment for thrush it is carried out with tablets.

It is recommended that therapeutic measures Both partners were involved, since the male half is also prone to thrush, regardless of the fact that it occurs extremely rarely in them. At the same time, it is the representatives of the stronger sex who are carriers of candidiasis and can become a source of recurrence of the disease.

Treatment of candidiasis in men is carried out using Pimafucin cream. The product should be applied to the affected areas of the genital mucosa once a day.

In case of a complicated form of the disease, the specialist prescribes application of the product several times a day. The time period of treatment depends on the doctor's prescription.

Treatment of thrush. Video

The active ingredient of Pimafucin is natamycin. Although it belongs to the group of broad-spectrum antibiotics, you should not be afraid of it. Natamycin is practically not absorbed from the gastrointestinal tract, from the surface of the skin and mucous membranes, that is, it does not enter the bloodstream, and therefore to the fetus during pregnancy.

However, if you have already experienced allergic reactions on Pimafucin, it cannot be used during pregnancy.

Candles can be used even in pediatric practice- for the treatment of pediatric patients, and are not prohibited for use during breastfeeding.

For thrush you should:

limit the consumption of butter and sweets;
consume lactic acid products;
refuse synthetic underwear;
do not use intimate hygiene products;
stop using panty liners;
strengthen your immune defense.

A large number of women and men who sought treatment for candidiasis and were prescribed Pimafucin speak positively about the drug. They note that the effectiveness of treatment with the drug is high, and the duration of therapy is short.

If you have been prescribed Pimafucin suppositories, you must read the instructions for use of the drug.

In it you will find full information about indications for use, side effects, features of use and effect of the medicine.

Pharmacological action and indications for use

Pimafucin suppositories are powerful antifungal agent. The medicine contains macrolide antibiotic natamycin. It has a wide antibacterial spectrum of action and leads to the death of fungal microorganisms by disrupting the integrity of their membrane. Natamycin is active against microorganisms of the Candida family and dermatophytes. The antibiotic is not absorbed into the area of the digestive canal and is not absorbed into the skin or mucous membranes.

Pimafucin is prescribed for fungal diseases of various etiologies. These may be vulvovaginitis caused by exposure to fungi of the Candida family, fungal diseases organs of the gastrointestinal tract, which arose due to weak immunity or long-term use certain medications. Pimafucin is also prescribed for the treatment of fungal diseases of the skin or nails.

The medicine is contraindicated in case of intolerance to natamycin, potato starch, gelatin, lactose or other auxiliary components of the medicine. Pimafucin suppositories are allowed to be used during pregnancy. In addition, the period of breastfeeding is also not a contraindication.

Directions for use and reviews

Suppositories must be inserted into the vagina. There is no need to pre-wet suppositories. The dosage will depend on the severity of the disease and the age of the patient. The duration of treatment varies from 1 week to several months. If the disease is difficult to treat, then drug therapy is supplemented by mouth Pimafucin tablets. After disappearing characteristic symptoms It is recommended to use the medicine for a few more days.

Pimafucin suppositories for thrush are a gentle remedy and do not cause side effects. However, during the first stages of treatment, a slight burning sensation or itching in the genital area may occur, which will go away on its own over time. If drug therapy is supplemented by taking Pimafucin tablets, then the person has a risk of nausea or diarrhea.

Reviews about Pimafucin

Angela, 32 years old. When I was pregnant for the second time, I was diagnosed with thrush. The doctor advised me to use Pimafucin suppositories. Within a week, the symptoms of candidiasis disappeared. The drug has a gentle effect, so I did not experience any side effects. I was satisfied with the candles.

Victoria, 26 years old. WITH youth suffered from chronic thrush. No pills or suppositories helped me. I recently came across an article on the Internet about Pimafucin suppositories; the reviews about the drug were extremely positive. I decided to use this medicine. After the course of treatment, which lasted about 2 weeks, the symptoms of candidiasis disappeared.

Tamara, 23 years old. After giving birth I had curdled discharge from the vagina. The doctor said that this is thrush, and it often occurs in women after childbirth due to weakened immunity. The doctor prescribed me Pimafucin suppositories, because they are safe and cannot harm the baby. The medicine helped - within a few days my condition improved significantly. I recommend that everyone use sanitary pads when using suppositories, as the medicine can leave yellow stains on your underwear.

Pimafucin's analogs

The best analogues of Pimafucin suppositories are Primafungin and Livarol.

Primafungin has similar composition and operating principle. The medicine can be used during pregnancy and breastfeeding. The drug has no side effects. Primafungin should not be used only if you are intolerant to natamycin. It is worth noting that suppositories should not be used during menstruation.

The active component of Livarol is ketoconazole. This substance has a wide antifungal spectrum actions. Ketoconazole is active against yeast-like fungi and dermatophytes. You can use Livarol suppositories in the treatment of vaginal candidiasis and as a prevention of fungal diseases. The medicine should not be used if you have an allergic reaction to ketoconazole or auxiliary components Livarola. Contraindications also include the first trimester of pregnancy. Livarol usually does not cause side effects, but some people experience irritation and a burning sensation in the genital area while using the medicine. Moreover, in the initial stages drug therapy Dizziness and nausea may occur.

"Pimafucin" is a modern drug containing a polyene antibiotic, which belongs to the group of macrolides. The drug has a very broad spectrum of action, which is achieved due to its strong fungicidal properties, which helps in active struggle with fungal infections. The drug "Pimafucin" is prescribed to women who suffer from vaginal candidiasis, or, as this disease is also called, thrush.

They are also effective for diseases such as trichomoniasis, as an additional remedy for the implementation of complex therapy diseases.

We will consider analogues of Pimafucin suppositories in this article.

Vaginal candidiasis

This disease is one of the most common in the field of gynecology today. The so-called thrush is fungal infection vaginal mucosa, which is caused by fungi of the genus Candida. The disease can occur under the influence of a wide variety of factors, which include a decrease in general immunity, unprotected sexual intercourse, and taking medications. antimicrobial agents and antibiotics. On different stages Almost every woman faces this problem in her life. For many, this may be associated with the onset of menstruation or frequent stress.

Almost every person is a carrier of the fungus, but its amount in the body must meet certain standards. However, in cases where the fungus begins to actively reproduce, the woman experiences symptoms such as a sharp burning sensation in the external genital area and severe itching. Main feature thrush, which distinguishes it from other inflammatory and infectious diseases of the genital organs, are specific secretions, similar to curd mass. Similar symptoms disappear, as a rule, already in the first days of treatment, however, to achieve stable and long lasting effect it must be carried out in a course of at least 10 days, together with a sexual partner.

Let's look at how Pimafucin suppositories work. Analogues will be presented below.

Pharmacological properties of the drug

Main active substance medication- natamycin (an antibiotic belonging to the group of macrolides). This substance can actively react to cell membranes yeast-like fungi, which contributes to their destruction and death. In addition, natamycin is active against several other pathogenic microorganisms, which can cause vaginal dysbiosis and thrush. Pathological bacteria such as dermatophytes are also sensitive to this active substance.

When applied topically in the form of suppositories, the drug “Pimafucin” is not absorbed into the blood, which does not cause any systemic disturbances in the functioning of the entire body.

Part vaginal suppositories In addition to the main active ingredient, there are also auxiliary ingredients - lactose, potato starch, gelatin and others.

Release form

One suppository contains 100 mg active substance. The suppositories have a yellowish and sometimes brownish tint and are available in packages of 3 or 6 suppositories. It’s easy to find cheaper analogues for Pimafucin candles.

Indications for use

Vaginal suppositories are prescribed for the following diseases:

vulvitis;
vaginitis;
vulvovaginitis;
vaginal candidiasis.

Drug interactions

Pimafucin suppositories and analogues have not been found to be incompatible with the components of other medications.

Directions for use and dosage

For any infectious and inflammatory diseases of the genital organs, the drug is prescribed once a day. The medication is intended for course treatment, and its duration should be at least three days at mild flow disease, and less than six days - with average.

The product should be used topically, by inserting into the vagina at maximum depth, taking a horizontal position of the body. This should be done once, before going to bed. This is confirmed by the instructions for use for Pimafucin. Analogues of candles are usually used in the same way.

For systematic recurrent manifestations of vaginal candidiasis and other diseases that are provoked by the proliferation of pathogenic microorganisms, it would be advisable to take antifungal drug orally in the form of tablets against the background of the main treatment with vaginal suppositories. The duration of such a course must be at least 10 days. Tablets are necessary to destroy foci of infection in the intestines, which may be chronic.

Should be paid Special attention that treatment should be carried out not only for the patient, but also for her sexual partner, since he can also be a carrier of the infection. To treat your partner, you can use the drug “Pimafucin” in the form of a cream, which should be applied to the genitals several times a day. The duration of the course of such treatment varies depending on the degree of the disease and is determined in each case individually.

Is it possible to use Pimafucin suppositories and analogues during pregnancy? Let's look at it below.

Side effects

Side effects of this medication may include slight itching and burning in the genital area, as well as minor irritation of the mucous membranes of the vagina. This effect may be due to the fact that the drug contains cetyl alcohol as an excipient. Despite manifestation of symptoms associated with side effects, it is not recommended to interrupt treatment. One more side effect from the use of vaginal suppositories is that in the first days of treatment, the symptoms of thrush may worsen slightly, but this also should not be a reason to discontinue therapy. This indicates instructions for the Pimafucin suppositories. Analogues should be selected by a doctor.

Contraindications

The only contraindication for women who are prescribed the drug is individual intolerance active or excipients of the drug. Extremely in rare cases Local allergic reactions may occur in the form of itching and discomfort in the vagina.

Use during pregnancy and breastfeeding

Vaginal suppositories approved for use by nursing women, as well as those who are in the process of bearing a child. When applied topically, the components of the drug are not absorbed, so they do not enter the blood of the expectant mother or milk.

Dispensing conditions and storage rules for vaginal suppositories “Pimafucin”

In order to purchase this medical product at the pharmacy, no doctor's prescription required. The drug should be stored in moderate low temperatures.

Analogues of Pimafucin suppositories

You can find it in pharmacies medications, which contain the same active substance. They are Primafungin, Natamycin and Ecofucin.

In addition, there are a number of medicines that are not analogues of Pimafucin suppositories for thrush, but have similar pharmachologic effect. These include:

"Betadine."
"Terzhinan."
"Fluomizin."
"Livarol."
"Polygynax".
"Miconazole".
"Zalain."

What is the best price to buy analogues for Pimafucin suppositories? These will be cheaper means: "Metronidazole","Fluconazole", "Ecostat", "Hexicon", "Flucostat".