Normaks children's instructions for use. Tablets from cystitis normax

Name:

Normaks (Normax)

Pharmacological
action:

Antibacterial drug from the group of fluoroquinolones.
It has a wide spectrum of bactericidal action. It inhibits the enzyme DNA-gyrase of bacteria, as a result of which DNA replication and the synthesis of cellular proteins of bacteria are disrupted.
Highly active against Gram-negative bacteria: Escherichia coli, Salmonella spp., Shigella spp., Proteus spp. (indole positive and indole negative), Morganella morganii, Citrobacter spp., Klebsiella spp., Enterobacter spp., Yersinia enterocolitica, Vibrio spp., Campylobacter spp., Hafnia spp., Providencia stuartii, Haemophilus influenzae, Pasteurella multocida, Pseudomonas spp., Gardner ella spp., Legionella pneumophila, Neisseria spp., Moraxella catarrhalis, Acinetobacter spp., Brucella spp., Chlamydia spp.
Active against Gram-positive bacteria: Staphylococcus spp., Streptococcus spp., Corynebacterium diphtheriae, Listeria monocitogenes.

Pharmacokinetics
Studies of the pharmacokinetics of the drug Normaks were not conducted due to low systemic absorption.

Indications for
application:

Treatment of acute and chronic infectious and inflammatory diseases, caused by susceptible microorganisms:
- conjunctivitis (including gonococcal);
- keratitis;
- keratoconjunctivitis;
- corneal ulcer;
- blepharitis;
- blepharoconjunctivitis;
- trachoma;
- otitis externa;
- acute and chronic otitis media;
- otitis media;
- infectious eustachitis.

Prevention of eye infections after removal of a foreign body from the cornea or conjunctiva, after damage by chemical or physical means, before and after surgical interventions.
Prevention of infectious otitis media before and after surgical interventions, with ear injuries, removal of a foreign body from the external auditory canal, accompanied by damage to the ear tissues.

Mode of application:

The drug is intended for instillation into the eye or ear.
Before using the drug, wash your hands thoroughly.
In severe infectious diseases, the drug is recommended to be used in combination with antimicrobial agents for oral or parenteral use.
The duration of the course of treatment and the dose of the drug is determined by the attending physician individually for each patient.
In acute infectious diseases of the eye, 1-2 drops of the drug are usually prescribed with an interval of 15-30 minutes, after which the interval between applications of the drug is gradually increased, depending on the dynamics of the disease.

In case of infectious diseases of the eyes of moderate severity, 1-2 drops of the drug are usually prescribed from 2 to 6 times a day.
Patients with acute or chronic trachoma are usually prescribed 2 drops of the drug in each eye 2 to 4 times a day.
The duration of the course of treatment may exceed 1-2 months.
Patients with infectious diseases of the external and middle ear are usually prescribed 2-3 drops of the drug 4 to 6 times a day.
In the acute period, it is allowed to use a single dose of the drug at intervals of 2-3 hours until the condition improves.

Side effects:

From the digestive system: nausea, heartburn, anorexia, diarrhea, abdominal pain.
From the CNS: headache, dizziness, fatigue, sleep disturbances, irritability, anxiety.
allergic reactions: skin rash, itching, angioedema.

Contraindications:

Hypersensitivity to norfloxaccin and other quinolone drugs.
Appointment not recommended the drug during pregnancy, lactation, as well as children and adolescents under the age of 18 years.

Normax is for topical use only.
To achieve the best therapeutic effect, drops should be used in combination with systemic antimicrobial therapy (with the exception of mild cases).
The solution and dropper should be protected from contamination.
Influence on the ability to drive vehicles and control mechanisms
Within 30 minutes after instillation of the drug into the eyes, one should refrain from engaging in potentially hazardous activities that require increased attention.

Interaction
other medicinal
by other means:

Pharmaceutical interaction
Norfloxacin solution is incompatible with medicinal products having a pH value of 3-4, which are physically or chemically unstable.
When combined with the use of the drug with other local drugs used in ophthalmic and ENT practice, the interval between the use of these drugs should be at least 15 minutes.

Normax is an antibacterial drug belonging to the group of fluoroquinolones.

Release form and composition

The drug is produced in the form of coated tablets, 0.3% eye and ear drops.

The composition of Normax tablets includes:

400 mg norfloxacin;
Excipients: sodium lauryl sulfate, microcrystalline cellulose, magnesium stearate, purified talc, colloidal silicon dioxide, sodium starch glycolate, titanium dioxide and hydroxypropyl methylcellulose.

Tablets are sold in 6 or 10 pcs. in strips of aluminum foil, packed in cardboard boxes.

1 ml of Normaks drops contains:

3 mg norfloxacin;
Additional components: benzalkonium and sodium chloride, disodium edetate, injection water and glacial acetic acid.

5 ml drops are sold in dark glass bottles complete with a dropper cap or in polyethylene dropper bottles.

Indications for use

According to the instructions for Normaks, in the form of tablets, the drug is prescribed for the treatment of infectious and inflammatory diseases, the pathogens of which are sensitive to norfloxacin. In particular, it is used for:

Diseases of the urinary tract;
Infections of the skin and soft tissues;
Intestinal infectious diseases;
Infections of the pelvic organs, incl. with adnexitis and prostatitis;
Infectious diseases of the middle ear, larynx, pharynx and nose;
Ophthalmic infections.

In the form of Normax drops, according to the instructions, it is intended for the treatment of the following infectious and inflammatory diseases:

Conjunctivitis, including gonococcal genesis;
Keratitis;
Corneal ulcer;
Keratoconjunctivitis;
Blepharitis;
Trachoma;
External otitis;
Blepharoconjunctivitis;
Internal otitis;
Acute and chronic otitis media;
Infectious eustachitis.

Normaks drops are recommended to be used to prevent the development of eye infections in the period before and after surgical interventions, after damage by physical or chemical means, and also after removal of a foreign body from the conjunctiva or cornea.

In addition, in the form of drops, the drug is prescribed to prevent the development of infectious otitis media before and after surgery, as well as for ear injuries, after removing a foreign body from the external auditory canal in cases where ear tissue damage is diagnosed.

Contraindications

The use of Normax, regardless of the form of release, is contraindicated:

Children under 15;
During pregnancy;
breastfeeding women;
In case of hypersensitivity to norfloxaccin, any auxiliary component of the drug or any other agent of the fluoroquinolone series.

The drug should be used with caution in patients with severe impairment of liver and kidney function, and in the form of tablets also in epilepsy or convulsive syndrome of another etiology.

Method of application and dosage

Normaks tablets are taken orally, as a rule, 1 pc. twice a day. In some cases, a single dosage may be increased to 2 tablets (800 mg of norfloxaccin).

The duration of Normaks application in each case is determined individually, taking into account the type of pathogen, the severity of the disease and the effectiveness of the therapy. The minimum course is 3 days.

In case of ophthalmic diseases Normaks drip 1-2 drops into the affected eye. The first few hours of instillation are usually recommended every 15-30 minutes, then the frequency is reduced. With moderately pronounced processes, 1-2 are prescribed from two to six times a day. In acute or chronic trachoma - 1-2 drops two to four times a day. The duration of treatment is determined individually, in the latter case, the course is at least one month.

For ear diseases, Normax is prescribed 2-5 drops three times a day. The tool must have the temperature of the human body. Before instillation, sanitation (cleansing) of the external auditory canal should be carried out, lie on one side or tilt your head back for ease of instillation. After the procedure, it is necessary to keep the head in the indicated position for about 2 minutes. If necessary, a cotton turunda can be placed in the external auditory meatus. The duration of treatment is determined individually. After the complete disappearance of the symptoms of the disease for another two days, it is recommended to continue the use of Normaks.

Side effects

Possible side effects of the drug:

Nausea, diarrhea, anorexia, heartburn, abdominal pain (from the digestive system);
Headache, sleep disorders, dizziness, anxiety and / or fatigue, irritability (reactions from the central nervous system);
Interstitial nephritis (from the urinary system).

Both oral administration and topical application of Normaks may cause allergic reactions, especially with hypersensitivity or intolerance to the active / excipients. They are usually manifested by a rash, itching, Quincke's edema.

special instructions

Within 30 minutes after instillation of the eyes, you should refrain from driving and performing potentially hazardous activities.

Analogues

Analogues of Normaks:

In the form of tablets: Abactal, Avelox, Gatispan, Glevo, Geoflox, Zanocin, Ificipro, Quintor, Levolet, Levoflox, Loxon-400, Lomacin, Lofox, Maklevo, Nolicin, Norbactin, Norilet, Norfacin, Norfloxacin, Oflo, Ofloxabol, Ofloxacin, Pefloxacin, Procipro, Remedia, Sparbakt, Sparflo, Tavanic, Tarivid and others;
In the form of eye / ear drops: Betaciprol, Vigamox, Vitabact, Dancil, Decamethoxin, Zimar, Conjunctin, Levofloxacin, Lofox, Okatsin, Okomistin, Ofloxacin, Oftadek, Oftaquix, Ophthalmol, Oftocypro, Signicef, Uniflox, Floxal, Ciloxan, Ciprolet, Ciprolon , Tsipromed, Ciprofloxacin, etc.

Terms and conditions of storage

Normaks is a drug dispensed from pharmacies by prescription. Regardless of the form of release, it should be stored in a dark place at temperatures up to 25 ºС. The shelf life of tablets is 3 years, drops - 2 years, and after opening the bottle - 1 month.

Normax is an antimicrobial agent belonging to the group of fluoroquinolones. Normax drops are used mainly for the treatment of ears and eyes and can be used at home.

Due to its mild composition and effect, the product is prescribed and successfully used by ENT specialists and ophthalmologists.

In this article, we will look at why doctors prescribe Normax, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS of people who have already used Normaks can be read in the comments.

Composition and form of release

Normax is available in the form of tablets and 3% ear and eye drops.

The composition of the drug includes norfloxacin, distilled water, sodium chloride, disodium edetate, glacial acetic acid, benzalkonium chloride.

Clinical and pharmacological group: antibacterial drug of the fluoroquinolone group for topical use in ophthalmology and ENT practice.

Indications for use Normaks

The indication for prescribing drops is the treatment of infectious and inflammatory diseases (acute and chronic course) provoked by microorganisms sensitive to Normax: trachoma, keratitis, external and internal otitis media, blepharitis, conjunctivitis (including gonococcal), keratoconjunctivitis, infectious eustachitis, corneal ulcer, chronic and acute otitis media, blepharoconjunctivitis.

Normaks drops are recommended to be used to prevent the development of eye infections in the period before and after surgical interventions, after damage by physical or chemical means, and also after removal of a foreign body from the conjunctiva or cornea.

pharmachologic effect

Norfloxacin, which is part of the drug, has an antimicrobial effect against gram-negative and gram-positive aerobic bacteria. These drops are not effective against infectious diseases caused by anaerobic bacteria.

Both gram-positive and gram-negative microorganisms are sensitive to the action of Normax, namely:

staphylococci;
klebsiella;
streptococci;
shigella;
legionella;
non-isseria gonorrhea;
citrobacter;
hemophilic bacillus;
Pseudomonas aeruginosa;
Proteus;
moraxella, etc.

Nevertheless, the anaerobic group of bacteria is not sensitive to the action of ear drops.

Instructions for use

According to the instructions for use, Normaks drops are intended for instillation into the ear or eye.

Assign 1-2 drops to the affected eye or ear 4 times / day. If necessary, on the first day of use, the dose can be increased to 1-2 drops every 2 hours. After the disappearance of the symptoms of the disease, the drug should be continued for the next 48 hours.

Before instillation of Normax drops into the ear, sanitation of the external auditory canal should be carried out. Drops must have body temperature. The patient should lie on their side or tilt their head back to facilitate instillation. After instillation, you need to let the drops drain into the ear canal, pulling the earlobe down and back. The head should be held in this position for about 2 minutes. You can place a cotton turunda in the external auditory meatus.

Contraindications

You can not use the drug in such cases:

Individual intolerance or hypersensitivity to Normax or its components;
Periods of pregnancy and lactation
Use in patients under 12 years of age.

Side effects

This medication has a number of side effects. They appear quite rarely, and the most common of them are:

From the skin: redness, itching, urticaria, Quincke's edema;
From the digestive tract: abdominal pain, heartburn, nausea, diarrhea;
From the side of the central nervous system: dizziness, headache, insomnia, weakness, fatigue, irritability, anxiety.

Within 30 minutes after instillation of the eyes, you should refrain from driving and performing potentially hazardous activities.

Analogues Normaks

Structural analogues for the active substance:

Lokson 400;
Nolicin;
Norbactin;
Norilet;
Noroxin;
Norfacin;
Norfloxacin;
Renor;
Sofazin;
Chibroxin;
Youtibid.

Attention: the use of analogues must be agreed with the attending physician.

Name: Normaks (Normax)

Release form, composition and pack

Film-coated tablets

1 tab. norfloxacin 400 mg.

Excipients: microcrystalline cellulose, purified talc, sodium starch glycolate, colloidal silicon dioxide, sodium lauryl sulfate, magnesium stearate, hydroxypropyl methylcellulose, titanium dioxide.

Clinico-pharmacological group: Antibacterial product of the fluoroquinolone group.

pharmachologic effect

An antibacterial product from the group of fluoroquinolones. It has a wide spectrum of bactericidal action.

Highly active against gram-negative bacteria: Escherichia coli, Haemophilus influenzae, Haemophilus ducreyi, Klebsiella spp. (including Klebsiella pneumoniae), Morganella morganii, Neisseria spp. (including Neisseria gonorrhoeae), Salmonella spp., Shigella spp., Proteus spp., Pseudomonas aeruginosa, Enterobacter spp., Chlamydia trachomatis, Citrobacter freundii, Serratia spp., Yersinia spp.

Active against gram-positive bacteria: Staphylococcus aureus (including penicillinase-producing strains and methicillin-resistant strains), Staphylococcus epidermidis, Staphylococcus saprophyticus, some strains of Streptococcus spp.

Enterococcus spp. are not very sensitive to the product. and Acinetobacter spp.

Anaerobic bacteria are resistant to Normax.

Pharmacokinetics

When taken orally, 30-40% of the dose is absorbed, food intake reduces the rate of absorption. Norfloxacin is well distributed in the tissues of the genitourinary system. About 30% of the active substance is excreted in the urine unchanged.

With local use of the product, the therapeutic concentration of the active substance is achieved in the tissues and biological fluids of the eye or in the tissues of the ear.

Indications

For oral administration

diseases of the urinary tract;

infections of the pelvic organs (including adnexitis, prostatitis);

intestinal infections;

skin and soft tissue infections;

infections of the paranasal sinuses, pharynx, larynx, middle ear;

ophthalmic infections.

For topical application

Treatment of infectious and inflammatory diseases caused by microorganisms sensitive to the product:

conjunctivitis (including gonococcal);

keratitis;

keratoconjunctivitis;

corneal ulcer;

blepharitis;

blepharoconjunctivitis;

trachoma;

otitis externa;

acute and chronic otitis media;

otitis media;

infectious eustachitis.

Prevention of eye infections after removal of a foreign body from the cornea or conjunctiva, after damage by chemical or physical preparations, before and after surgical interventions.

Prevention of infectious otitis media before and after surgical interventions, with ear injuries, removal of a foreign body from the external auditory canal, accompanied by damage to ear tissues.

Dosing regimen

Inside take 400 mg 2 times / day. In severe infections, a single dose can be increased to 800 mg. The duration of treatment is determined individually. The minimum course of treatment is 3 days.

Locally for acute infectious eye diseases, the product is prescribed 1-2 drops every 15-30 minutes, then the frequency of instillations is reduced. With a moderately pronounced process, 1-2 drops are prescribed 2-6 times / day.

In acute and chronic trachoma, 2 drops are prescribed in each eye 2-4 times / day for 1-2 months or more.

For ear diseases, 5 drops are prescribed in the ear 3 times / day. Drops must have body temperature. Before using Normax ear drops, it is necessary to sanitize the external auditory canal. The patient should lie on their side or tilt their head back to facilitate instillation. After instillation, the head should be kept in the indicated position for about 2 minutes. You can place a cotton turunda in the external auditory meatus. After the disappearance of the symptoms of the disease, the use of the product should be continued for the next 48 hours.

Side effect

From the digestive system: nausea, heartburn, anorexia, diarrhea, abdominal pain.

From the side of the central nervous system: headache, dizziness, fatigue, sleep disorders, irritability, anxiety.

From the urinary system: interstitial nephritis is possible. Allergic reactions: when taken orally and locally, skin rash, itching, Quincke's edema are possible.

Contraindications

children and adolescents up to 15 years;

pregnancy;

lactation (breastfeeding);

high susceptibility to norfloxaccin and other fluoroquinolone products.

Pregnancy and lactation

Application for violations of liver function

Normax in the form of tablets should be used with caution in patients with severe liver dysfunction.

Application for violations of kidney function

Normax in the form of tablets should be used with caution in patients with severe renal impairment.

special instructions

Normax in the form of tablets should be used with caution in patients with epilepsy, convulsive syndrome of another etiology, severe liver and / or kidney dysfunction.

The drug should be taken at least 2 hours before or 2 hours after taking antacids or products containing iron, magnesium, zinc or sucralfate.

Normaks in the form of drops is intended for topical use only.

To achieve the best therapeutic effect, drops should be used in combination with systemic antimicrobial therapy (except for mild cases).

The solution and dropper should be protected from contamination.

Influence on the ability to drive vehicles and control mechanisms

Within 30 minutes after instillation of the product into the eyes, one should refrain from engaging in potentially hazardous activities that require increased attention.

Overdose

At present, no cases of overdose of the Normax product have been reported.

Possible symptoms in case of accidental ingestion of drops inside: nausea, vomiting, diarrhea, headache, dizziness, anxiety.

Treatment: if necessary, carry out symptomatic therapy; it is necessary to ensure sufficient fluid intake in the body, the creation of an acidic urine reaction to prevent crystalluria.

drug interaction

With the simultaneous administration of Normax and warfarin, the anticoagulant effect is enhanced in the aftermath.

With the simultaneous administration of Normax and cyclosporine, an increase in the concentration of the latter in the blood plasma is noted.

While taking Normax with antacids or products containing iron, magnesium, calcium, zinc, sucralfate, the absorption of norfloxacin is reduced due to the formation of chelators with metal ions.

Pharmaceutical interaction

Norfloxacin solution is incompatible with medicinal products having a pH value of 3-4 that are physically or chemically unstable.

Storage conditions and periods

The drug in the form of eye and ear drops should be stored in a place protected from light, out of the reach of children, at temperatures up to 25 ° C. The shelf life is 2 years. After opening the bottle, the drops should be used within 1 month.

Attention!
Before using the medication "Normax (Normax)" it is necessary to consult a doctor.
The instructions are provided solely for familiarization with " Normaks (Normax).Did you like the article? Share with friends in social networks:

Normax is an antibacterial drug belonging to the group of fluoroquinolones with a wide spectrum of bactericidal action.

Release form and composition

Film-coated tablets: capsule-shaped, white or almost white, with a risk on one side (6 or 10 pieces in aluminum foil strips, 1 strip in a carton box);
Eye and ear drops 0.3%: a clear, colorless or slightly yellow solution, free from any particles (5 ml each in dark glass bottles complete with a dropper cap or polyethylene dropper bottles, 1 bottle in a carton box).

The active substance is norfloxacin:

1 tablet - 400 mg;
1 ml drops - 3 mg.

Auxiliary components:

Tablets: purified talc, magnesium stearate, colloidal silicon dioxide, sodium starch glycolate, sodium lauryl sulfate, titanium dioxide, microcrystalline cellulose, hydroxypropyl methylcellulose;
Eye and ear drops: glacial acetic acid, sodium chloride, disodium edetate, benzalkonium chloride, injection water.

Indications for use

Normax is a drug for the treatment of infectious and inflammatory diseases, the causative agents of which are microorganisms sensitive to norfloxacin.

For tablets:

intestinal infections;
Infections of the pelvic organs (including adnexitis and prostatitis);
Diseases of the urinary tract;
gonococcal infection;
Ophthalmic infections;
Infections of the skin and soft tissues;
Infections of the pharynx and larynx, paranasal sinuses, middle ear;
travelers diarrhea;
Prevention of sepsis in patients with neutropenia.

For eye and ear drops:

Blepharitis;
Keratitis;
Conjunctivitis (including gonococcal);
Keratoconjunctivitis;
Blepharoconjunctivitis;
Internal otitis;
Acute and chronic otitis media;
External otitis;
Infectious eustachitis;
Trachoma;
Corneal ulcer.

In the form of eye and ear drops, Normax is also used for prophylactic purposes:

Prevention of infectious otitis when removing a foreign body from the external auditory canal, accompanied by damage to the tissues of the ear, with ear injuries, before and after surgical interventions;
Prevention of infections after damage by physical or chemical means, removal of a foreign body from the conjunctiva or cornea, before and after surgical interventions.

Contraindications

Age up to 15 years - for tablets, up to 18 years - for drops;
Pregnancy;
Breast-feeding;
Individual hypersensitivity to Normax components or other fluoroquinolone preparations.

In the form of tablets, the drug should be used with caution in epilepsy or convulsive syndrome of another etiology, as well as in violation of the function of the kidneys and / or liver.

Method of application and dosage

Film-coated tablets

In the form of tablets, Normax should be taken orally on an empty stomach (at least 1 hour before a meal or 2 hours after a meal), drinking plenty of water.

Acute uncomplicated cystitis: 200-400 mg 2 times a day for 3-5 days;
Acute urinary tract infections: 400 mg 2 times a day for a 7-10-day course;
Recurrent and chronic recurrent urinary tract infections: 400 mg 2 times a day for 4 weeks and in case of relapse - 400 mg per day for up to 12 weeks;
Infections of the digestive system: 400 mg 2 times a day for 3-5 days;
Acute uncomplicated gonococcal infection: 800 mg once;
Infections of the genital organs: 400-600 mg 2 times a day for a 7-day course;
Prevention of bacterial diarrhea: 400 mg 1 time per day;
Prevention of sepsis in patients with neutropenia: 400 mg 3 times a day for 8 weeks;
Other indications: 400 mg 2 times a day, for severe infections - 800 mg, a course of at least 3 days.

For patients with renal insufficiency and creatinine clearance of 10-30 ml / minute, the dose is reduced to 400 mg 1 time per day.

Drops eye and ear

In the form of drops, the drug is applied topically.

Ophthalmic infections:

Acute infectious eye diseases: at the beginning of treatment - 1-2 drops every 15-30 minutes, then the frequency of instillations is reduced;
Moderate eye infections: 1-2 drops 2 to 6 times a day;
Acute and chronic trachoma: 2 drops in each eye 2-4 times a day for 1-2 months, longer treatment is possible.

For ear diseases, 5 drops per ear are used 3 times a day, the external auditory canal must first be sanitized. Before instillation, the drops must be heated to body temperature. For ease of use of the drug, you need to lie on your side or throw your head back. After instillation, the head should be kept in the same position for about 2 minutes. If necessary, a turunda can be placed in the external auditory meatus.

Normax is indicated for use until the symptoms disappear and for another 48 hours thereafter.

Side effects

When using Normaks in the form of drops:

Digestive system: abdominal pain, diarrhea, heartburn, nausea, anorexia;
Central nervous system: increased fatigue, irritability, sleep disorders, dizziness, anxiety, headache;
Allergic reactions: skin rash, angioedema, itching.

When using Normaks in the form of tablets:

Urinary system: interstitial nephritis;
Gastrointestinal tract, liver: diarrhea, anorexia, nausea, transient increase in the activity of hepatic transaminases, lactate dehydrogenase and alkaline phosphatase;
Central nervous system, psyche: vertigo, headache, tinnitus, irritability, anxiety, fatigue, confusion, drowsiness, hallucinations, fear, depression;
Musculoskeletal system: in rare cases - tendon rupture, tendinitis;
Laboratory indicators: leukopenia, eosinophilia, increased plasma creatinine concentration, decreased hematocrit;
Allergic reactions: rarely - rash, urticaria, itching, anaphylactic shock.

special instructions

Pills

If necessary, the simultaneous use of antacids or preparations containing magnesium, sucralfate, iron or zinc, at least 2-hour intervals between doses should be observed.

During treatment, it is necessary to ensure sufficient fluid intake into the human body (under the control of diuresis).

The likelihood of an increase in the prothrombin index should be taken into account.

When carrying out surgical operations, it is necessary to control the state of the blood coagulation system.

In case of pain in the tendons, as well as when the first signs of tendovaginitis appear, it is recommended to stop the drug.

During the treatment period, it is necessary to avoid exposure to direct sunlight, be careful when driving a car and performing potentially hazardous types of work that require increased concentration.

Ear and eye drops

In the form of drops, Normaks is intended for topical use only. When instilling, in order to avoid contamination of the drug, care should be taken not to touch the tip of the pipette to any surfaces.

To achieve a better therapeutic effect, drops are recommended to be used simultaneously with systemic antimicrobial therapy (with the exception of mild cases).

Within 30 minutes after instillation of the drug in the eyes, you should refrain from driving vehicles and performing potentially hazardous types of work.

drug interaction

Normax, taken orally simultaneously with other drugs:

Warfarin: its anticoagulant effect is enhanced;
Cyclosporine: its concentration in blood plasma increases;
Antacids and preparations containing magnesium, zinc, calcium, sucralfate, iron: absorption of norfloxacin is reduced.

Normax in the form of eye and ear drops is incompatible with preparations having a pH of 3-4, which are chemically or physically unstable.

Terms and conditions of storage

Store in a dry, dark place and out of the reach of children. Do not exceed a temperature of 25 ºС.

The shelf life of tablets is 3 years, drops - 2 years, after the first opening of the vial - 1 month.

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