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Trimedat is a drug that regulates the intensity of motor activity of organs digestive tract(mainly the intestines) and, accordingly, the speed of movement of the food bolus from the esophagus to the colon. Trimedat is used for relief various symptoms caused by motor disorders gastrointestinal tract, such as diarrhea or constipation, flatulence, intestinal colic, abdominal pain, cramps, nausea and vomiting.
Varieties, names, release forms and composition of Trimedat
Currently, Trimedat is available in the following two varieties:- Trimedat;
- Trimedat Valens.
And since the drug with the name “Trimedat” is produced by the South Korean pharmaceutical corporation “Dae Hau New Pharm Co.”, the right to this name also belongs to it. Therefore, the Russian pharmaceutical company Valenta began to produce the drug under the name Trimedat Valenta, which differs from the original by an additional word and is its own trademark.
However, since, in fact, the drugs Trimedat and Trimedat Valenta are varieties of the same medicine, we will use common name"Trimedat".
Trimedat is available in the only dosage form – tablets for oral administration. There are two dosage options for the active substance - 100 mg or 200 mg per tablet. That is, Trimedat is available in tablets with two dosages - 100 mg and 200 mg.
As active component
Trimedat contains trimebutine. As auxiliary components
Tablets of both dosages contain the following substances:
- Colloidal silicon dioxide;
- Corn starch;
- Magnesium stearate;
- Talc.
Tablets Trimedat produced in South Korea with a dosage of 100 mg are flat-cylindrical in shape, painted white and equipped with two embossed letters “TM” on one side and two intersecting marks on the other. Above and below the letters “TM” you can see three triangles located on the same line.
South Korean-made Trimedat tablets with a dosage of 200 mg have a round, biconvex shape, are painted white, and are also equipped with a line on one side and an embossed symbol in the form of two drops on the other.
Trimedat Valenta tablets of both dosages have the same shape and color - round, flat-cylindrical, white. 100 mg tablets are equipped with a chamfer on one side and two intersecting marks on the other. 200 mg tablets are equipped with one bevel and a score on different sides.
Action of Trimedat
The therapeutic effect of Trimedat is to equalize the intensity of peristaltic movements and contractions in all parts of the intestine, due to which food bolus moves evenly, at optimal speed, without stopping anywhere and, at the same time, not going too fast. By normalizing and equalizing the speed of movement of the food bolus through various parts of the intestine, the problem of symptoms of digestive disorders caused by various diseases of the stomach and intestines, such as increased gas formation (flatulence), bloating, abdominal pain, cramps, intestinal colic, diarrhea or constipation, is completely eliminated , as well as nausea and vomiting. Thus, the action of Trimedat ensures the elimination of painful symptoms accompanying diseases of the stomach and intestines or their functional disorders (for example, after taking large quantities fatty, spicy, spicy or other irritating foods, etc.). Therefore, Trimedat is used as a symptomatic medicine to relieve the painful manifestations of intestinal and stomach diseases.
The indicated therapeutic effect of Trimedat is achieved by its ability to normalize the intensity of peristaltic contractions of the intestine, that is, to accelerate in case of insufficiency and decrease in case of excess. In addition, the drug acts as antispasmodic, reducing tension and too strong tone smooth muscles of the intestine, which helps relieve spastic pain.
That is, Trimedat restores the intensity of movements of intestinal smooth muscles during various diseases, thereby normalizing the digestion process and eliminating the painful symptoms of intestinal dyspepsia (flatulence, diarrhea or constipation, bloating, cramping pain).
The advantage of the drug is that Trimedat normalizes intestinal motility, that is, it increases or decreases its intensity depending on the existing level in relation to the norm.
In addition, Trimedat optimizes the pressure of the esophageal sphincter and the rate of gastric emptying, which eliminates reflux of gastric contents. Stopping reflux, in turn, eliminates such unpleasant symptoms like nausea, vomiting and heartburn.
Indications for use
Trimedat tablets are indicated for use in the following cases:- Irritable bowel syndrome, accompanied by abdominal pain and colic, intestinal spasms, flatulence, diarrhea or constipation (or their alternation);
- Postoperative paralytic ileus;
- Gastroesophageal reflux disease (GERD);
- Dyspeptic symptoms with functional disorders ah gastrointestinal tract associated with impaired motility, such as swallowing air while eating, discomfort or pain in the stomach, a feeling of fullness or distension in the stomach after eating, rapid satiety;
- Dyspeptic disorders due to diseases of the stomach and intestines, such as flatulence, bloating, diarrhea or constipation (or their alternation), cramps and abdominal pain, nausea, vomiting;
- Preparing for an x-ray or endoscopic examination stomach or intestines;
- Dyspeptic symptoms in children (nausea, vomiting, diarrhea, constipation, flatulence, bloating, cramps and abdominal pain) associated with impaired motility of the gastrointestinal tract.
Trimedat - instructions for use
How to take Trimedat?
Trimedat tablets should be taken orally, swallowed whole, without biting, chewing or crushing in any other way, but with a drink. sufficient quantity water (it is optimal to take the tablets with 2/3 glasses of water).The dosage of Trimedat is the same for various diseases, but differs for children and adults. Currently, it is recommended to take Trimedat in the following dosages depending on age:
- Teenagers over 12 years old and adults
Thus, for the treatment of irritable bowel syndrome, Trimedat should be taken in the acute period, 200 mg 3 times a day for four weeks. Then, to prevent relapses and achieve stable remission at the end of 4 weeks, you should continue taking Trimedat at a dosage of 100 mg 3 times a day for 12 weeks in a row. This treatment regimen: 4 weeks of 600 mg per day + 12 weeks of 300 mg per day allows for the cure of irritable bowel syndrome in almost 100% of cases.
People suffering from irritable bowel syndrome in remission can undergo a course of Trimedat therapy, aimed at preventing relapses, taking 100 mg tablets three times a day for three weeks.
For functional disorders or diseases of the digestive tract (including cholecystitis, pancreatitis, gastritis, gastric ulcer and duodenum, GERD, etc.) Trimedat as a symptomatic drug should be taken in courses lasting 2 to 3 months for both children and adults. Moreover, courses of therapy are recommended to be repeated periodically, observing intervals of at least 3 months between them. Remember that the effect of Trimedat when chronic diseases develops and manifests itself only by the end of the second week of treatment, so short courses of therapy are useless in these cases.
When using Trimedat as a means emergency assistance, for example, for symptoms of dyspepsia in children (bloating, belching, nausea, spasms, intestinal colic, etc.), the drug should be given in age dosage for several days until the symptoms of the disorder completely go away. Likewise, adults can take Trimedat in short courses if symptoms of dyspepsia appear that are not associated with diseases or functional disorders of the gastrointestinal tract. That is, if a child or adult has bloating, nausea, colic or abdominal cramps, diarrhea not associated infectious disease(For example, " bear disease"), or flatulence, then to eliminate these symptoms you can take Trimedat in an age-appropriate dosage. In such cases, when the symptoms of dyspepsia occur occasionally and are not constantly present, the drug should be taken in short courses lasting 1 to 3 days.
When preparing for an X-ray or endoscopic examination of the digestive tract, take Trimedat 1-2 times in an age-appropriate dosage before the upcoming manipulation.
When treating postoperative paralytic ileus, Trimedat must also be taken at an age-specific dosage for at least 4 weeks. After four weeks of treatment, an assessment should be carried out motor activity intestines, and based on the data obtained, make a decision on stopping or continuing therapy.
Trimedat - before meals or after?
It is optimal to take the tablets 15–30 minutes before meals for both adults and children. If for some reason it is not possible to take Trimedat 15 to 30 minutes before a meal, then this can be done within 20 minutes after a meal. In this mode, the tablets should be taken as planned, throughout the entire course of therapy.However, if symptoms of dyspepsia (abdominal pain, colic and intestinal spasms) occur between meals, then Trimedat can be taken at urgently, and not as planned, and in this case there is no need to focus on food. That is, the drug can be taken at any time, regardless of meals.
Use during pregnancy and breastfeeding
During experimental studies on animals, Trimedat was not found to have negative influence on the fetus and the course of pregnancy. However, such trials, for obvious ethical reasons, were not conducted in pregnant women, so there is no precise data on the safety of the drug. That is why it is not recommended to take Trimedat during the first trimester of pregnancy (from the beginning to the end of the 13th week). And in the second and third trimesters, Trimedat can be taken only if the potential benefits outweigh all possible risks. Since it is unknown whether Trimedat passes into human milk, it is recommended to avoid using the drug throughout the entire period of breastfeeding. If it is necessary to take Trimedat for health reasons, then the child should be weaned and transferred to artificial formula.
Impact on the ability to operate machinery
Trimedat does not affect the functions of the central nervous system, and therefore, against the background of its use, you can engage in any type of activity that requires high speed reactions and concentration.Overdose
An overdose of Trimedat tablets was never detected during the entire period of observation of its clinical use.Interaction with other drugs
Interactions with other drugs have not been described for Trimedat. This means that Trimedat can be combined with any other medications necessary for effective treatment various diseases and conditions.Trimedat for children
Trimedat can be used to eliminate symptoms of dyspepsia in children caused by for various reasons. You should know that South Korean-made Trimedat can be used only for children from 12 years of age, and Russian Trimedat Valenta - from 3 years.Most often Trimedat in children of various ages used for symptoms of dyspepsia not associated with any diseases, such as:
- Abdominal pain;
- Discomfort, feeling of heaviness or fullness in the stomach;
- Nausea;
- Colic and intestinal spasms;
- Flatulence;
- Bloating;
- Constipation;
- Diarrhea not associated with an infectious disease or poisoning).
Since dyspepsia develops quite often in children, Trimedat is necessary drug in any home or travel medicine cabinet, as it quickly normalizes the child’s condition, relieving painful symptoms.
In addition, Trimedat can be used as part of complex therapy various diseases of the digestive tract in children, such as GERD, gastritis, gastroduodenitis, pancreatitis, etc. In such situations, Trimedat should be given to the child in an age-appropriate dosage in long courses of 1 to 3 months.
The dosage of Trimedat for children depends only on their age, and is the same for various conditions and diseases. This means that for any disease or condition, the child should be given Trimedat in the same dosage appropriate for his age.
- Teenagers over 12 years old– take 100–200 mg 3 times a day;
- Children aged 6 – 11 years inclusive– take 50 mg (half a tablet with a dosage of 100 mg) three times a day;
- Children aged 3 – 5 years inclusive– take 25 mg (quarter tablets with a dosage of 100 mg) three times a day.
Adolescents over 12 years of age are given whole tablets of the required dosage (100 mg or 200 mg), which they should swallow whole and wash down with clean, still water. For children 3 to 11 years old, Trimedat 100 mg tablets should be divided into two or four parts to obtain a dose of 50 mg or 25 mg. After the tablet is divided into required quantity parts can be given to a child required dosage two ways. Firstly, you can let your baby swallow half or a quarter of the tablet if he already knows how to do this. Secondly, you can grind half or a quarter of the tablet into powder, place it in a spoon, add a little water and let the child drink the resulting suspension.
The choice of method for taking Trimedat tablets for children aged 3 to 11 years depends on their preferences. That is, if it is more convenient for a child to swallow tablets, then you should give him a half or a quarter. If the child has difficulty swallowing tablets and is accustomed to liquid dosage forms (syrups, suspensions, solutions), then it is better to crush half or a quarter of Trimedat into powder, then dissolve it with water, turning it into a suspension, and give it to the baby in this form.
Trimedat for constipation
Trimedat has a regulating effect on intestinal motility, enhancing or, conversely, weakening it, depending on the need and the existing initial level. Moreover, in different departments intestines Trimedat can have the exact opposite effect - for example, in small intestine strengthen peristalsis, and in the thick, on the contrary, weaken it, or vice versa. This therapeutic effect of the drug leads to the fact that intestinal motility is normalized and synchronized, as a result of which the food bolus moves at an optimal speed, ensuring complete digestion. Accordingly, ensuring optimal peristalsis normalizes bowel movements, eliminating both constipation and diarrhea. That is why Trimedat can be used to treat both constipation and diarrhea (of non-infectious origin).For constipation, Trimedat is recommended for adults and adolescents over 12 years of age to take 100 mg 2-3 times a day 15-20 minutes before meals. Children 3-5 years old with constipation should be given Trimedat 25 mg 2-3 times a day, and children 6-11 years old should be given 50 mg 2-3 times a day also 15-30 minutes before meals. The duration of therapy depends on the speed of normalization of the bowel movement process. That is, you should take the pills until your bowel movements become regular.
Trimedat - analogues
The entire set of analogues of any drug, including Trimedat, is divided into two large groups - these are synonyms and, in fact, analogues. Synonyms are drugs containing the same active substance. This is why synonyms are also called structural analogues.Analogues are drugs that have the most similar spectrum therapeutic action, but containing different active substances. Such drugs are often called “analogues” medicinal effect".
Synonyms of Trimedat are medications that also contain trimebutine as an active substance. On the domestic pharmaceutical market There are the following drugs synonymous with Trimedat:
- Debridate solution (available in some CIS countries and Europe);
- Neobutin tablets;
- Tributate tablets (available in Ukraine);
- Trimpa 200 tablets (available only in Ukraine and Kazakhstan).
- Dicetel tablets;
- Duspatalin capsules;
- Iberogast drops for oral administration;
- Colofort lozenges;
- Niaspam capsules;
- Pepsan-R capsules and gel for oral administration;
- Spasmomen tablets;
- Sparex capsules;
- Trigan solution for injection;
- Enterosan capsules.
Why is the medication "Trimedat" prescribed? Instructions for use, analogues and indications for this drug will be described in detail in the presented article. In addition, you will learn how this drug acts on the human body and what side effects the patient may experience after taking it. We will also tell you what the best and most effective analogue exists.
"Trimedat" - what kind of drug?
This medication is a potent antispasmodic drug. Its main active substance trimebutine maleate is used. But in addition to it, Trimedat also includes such auxiliary elements as colloidal silicon dioxide, corn starch, lactose, talc and magnesium stearate.
Release form
The medication “Trimedat” (price, analogues will be discussed below), like almost everything else, is available in tablets. They white, have a risk in the middle (200 and 100 mg each). They go on sale in cardboard packages of 100, 30, 20 and 10 pieces.
pharmachologic effect
What properties does the drug “Trimedat” have (its equivalent in Ukraine is “Trimspa”)? According to the instructions included in the package, it is a medication that is intended to normalize motor functions and regulate the visceral sensitivity of the gastrointestinal tract. This happens due to contraction and relaxation of the intestines. Patients who take Trimedat claim that this medicine significantly facilitates gastric emptying. After taking it, the pressure of the esophageal sphincter is weakened, which, in turn, leads to the restoration of the full physiological activity of the intestinal muscles. It should also be noted that the drug "Trimedat" is able to ensure a timely response of the smooth muscle tissue of the colon to indigestible food. Each of its analogs has the same properties.
"Trimedat" is quickly and well absorbed. A couple of hours after administration it reaches its maximum concentration in the body. As for breakdown, it occurs in the liver. Output this drug along with urine. You can purchase such a medicine at a price ranging from 290-340 rubles (for 30 tablets of 200 mg).
Medication "Trimedat": indications for use
The instructions attached to the product state that it is prescribed for feelings of nausea, dyspeptic symptoms and disorders, as well as vomiting. The presented medication is used to treat gastroduodenal diseases, when the patient feels pain in the abdomen and stomach. In addition, this drug is actively used when the stomach feels full, as well as for digestive disorders. Trimedat is often prescribed for therapy:
- gastroesophageal reflux disease;
- irritable bowel syndrome, which manifests itself as colic;
- constipation or diarrhea;
- spasms in the intestines;
- pain in the abdomen.
Any analogue has similar indications for use. "Trimedat" and generics are used as part of combined preparation for x-ray or endoscopic examination stomach and intestines. In addition, such medications are very often used to treat dyspeptic disorders in young children caused by or associated with impaired motility of the gastrointestinal tract.
Dosage and method of administration
The drug "Trimedat" should be taken whole (without chewing the tablet) and washed down with water. For adolescents over 12 years of age and adults, this medication is prescribed orally at 100 or 200 mg three times a day. In order to prevent the development of irritable bowel syndrome, it is recommended to continue taking Trimedat during the period of remission at a dosage of 300 mg per day for 12 weeks. Each analogue is used in a similar way. Trimedat is prescribed to a child aged 5 to 12 years, 50 mg three times a day. For children younger age(from 3 to 5 years) - 2 times less, but with the same frequency.
It should be noted that for young patients, manufacturers produce the drug “Trimedat” in the form of a suspension. This remedy is prescribed according to the following scheme:
- for babies up to six months - ½ dessert spoon three or two times a day;
- for a child from six months to one year - 1 dessert spoon twice a day;
- children from one to five years old - a dessert spoon three times a day;
- children over five years old - 2 dessert spoons three times a day;
- adults - 2 large spoons three times a day.
Contraindications for use
The tableted drug is not recommended for children under 3 years of age. If the medication is still used, the child should be under the strict supervision of a pediatrician. Also, the presented medicine cannot be used in patients with hypersensitivity to at least one of the components. Trimedat should not be prescribed to women with breastfeeding, as well as in the first three months of pregnancy.
Side effects
According to reviews, this medication does not provoke side effects. However, very rarely, patients experience allergic reactions. Their nature is associated with intolerance to individual components.
The drug "Trimedat": analogues, reviews
Those who have ever taken this remedy speak of it exclusively with positive side. They claim that the medicine very quickly eliminates nausea and painful sensations in the abdominal area, and also removes muscle spasms. Negative opinions regarding medications are extremely rare.
Analogs of the presented drug (in terms of medicinal effect) include:
pharmachologic effect
Trimebutine, acting on the enkephalinergic system of the intestine, is a regulator of its peristalsis. Having an affinity for excitation and suppression receptors, it has a stimulating effect in hypokinetic conditions of intestinal smooth muscles and an antispasmodic effect in hyperkinetic conditions.
The drug acts throughout the gastrointestinal tract, reduces the pressure of the esophageal sphincter, promotes gastric emptying and increased intestinal motility, and also promotes the response of the smooth muscles of the colon to food irritants.
Trimebutine restores the normal physiological activity of the intestinal muscles in various gastrointestinal diseases associated with motility disorders.
Pharmacokinetics
Suction
After oral administration, trimebutine is rapidly absorbed from the gastrointestinal tract. Cmax in blood plasma is achieved after 1-2 hours. Bioavailability is 4-6%.
Distribution
The degree of binding to plasma proteins is low - about 5%. V d - 88 l. Trimebutine in minor degree penetrates the placental barrier.
Metabolism
Trimebutine is biotransformed in the liver.
Removal
Trimebutine is excreted in the urine mainly in the form of metabolites (approximately 70% during the first 24 hours). T 1/2 - about 12 hours.
Indications
- gastroesophageal reflux disease;
— motor disorders at functional diseases Gastrointestinal tract;
- dyspeptic disorders in gastroduodenal diseases (abdominal pain, indigestion, nausea, vomiting);
- irritable bowel syndrome, manifested by pain, colic in abdominal cavity, intestinal cramps, flatulence, diarrhea and/or constipation;
- postoperative paralytic intestinal obstruction;
— preparation for x-ray/endoscopic examination of the gastrointestinal tract;
— dyspeptic disorders in children associated with gastrointestinal motility disorders.
Dosage regimen
For adults And children over 12 years old the drug is prescribed orally at 100-200 mg 3 times a day. To prevent relapse of irritable bowel syndrome after a course of treatment during the period of remission, it is recommended to continue taking the drug at a dose of 300 mg/day for 12 weeks.
Children aged 5-12 years prescribed 50 mg 3 times a day, children aged 3-5 years- 25 mg 3 times/day.
Side effect
Rarely: skin reactions.Contraindications for use
- children under 3 years of age (for this dosage form);
— increased sensitivity to the components of the drug.
Use during pregnancy and breastfeeding
IN experimental studies There was no evidence of teratogenicity or embryotoxicity of the drug.
Use in children
The drug in this dosage form is not prescribed to children under 3 years of age.
Overdose
To date, no cases of overdose of Trimedat ® have been reported.
Drug interactions
Drug interactions with Trimedat ® have not been described.
Conditions for dispensing from pharmacies
The drug is approved for use as a means of OTC.
Storage conditions and periods
The drug should be stored out of the reach of children at a temperature not exceeding 25°C. Shelf life - 3 years.
special instructions
Treatment course for irritable bowel syndrome acute period 600 mg/day for 4 weeks and continuation of treatment after the course at a dose of 300 mg/day for 12 weeks helps to avoid relapse of the disease.
A drug for normalizing gastrointestinal motility. Shows a nonspecific effect on all organs, but has the ability to eliminate increased tone smooth muscles and restore decreased. Used to treat pathological conditions and relieve symptoms of dyspepsia in patients over 3 years of age.
Dosage form
Trimedat is available in only one dosage form - tablets for internal use. The manufacturer offers customers Trimedat in dosages of 100 and 200 mg. Trimedat Valenta (Russia) makes tablets round shape, white in color, which differ in the application of marks and chamfers, depending on the dosage. The Korean drug of a lower dosage has a “TM” engraving on the tablet, and with a dosage of 200 mg there is a symbol in the form of two drops.
The composition includes corn starch and lactose as auxiliary components, which should be taken into account by people who are intolerant to such substances.
Description and composition
Main active substance is trimebutine. By pharmacological action it is an agonist of opioid receptors, which are located in smooth muscles Gastrointestinal tract. Central action trimebutine does not have any effect. After taking the drug, impaired motility of the gastrointestinal tract is normalized. In hypokinetic conditions, it stimulates the intestines, and eliminates hyperkinetic manifestations. The effect occurs within half an hour after taking the tablet. Due to the non-specific action, the result appears on all organs of the digestive tract. Trimedat also has antispasmodic activity, which is very important for alleviating the condition of patients with gastrointestinal pathologies. Pharmacological effects:
- Stimulating the motility of the stomach and intestines.
- Decreased esophageal sphincter tone.
- Increased sensitivity of receptors in the colon, which leads to faster bowel movements.
The advantage of the drug is the ability to restore any pathology (hyper- or hypoactivity) to a normal state.
Pharmacological group
Trimedat is a drug that stimulates peristalsis.
Indications for use
for adults
The drug is prescribed for:
- Non-infectious dyspepsia, including those caused by gastroduodenal pathologies.
- Functional diarrhea.
- Irritable bowel syndrome.
- Gastroesophageal reflux.
- Postoperative intestinal obstruction.
- Preparing for research.
Trimedat makes peristalsis uniform, removing excessive spasms and stimulating weakened sections. Thanks to this, the food bolus moves freely and at the required speed. Improved digestion helps eliminate symptoms such as flatulence, bloating, cramps, pain, nausea, diarrhea and constipation.
for children
Trimedat is approved for children from the age of three for the same indications as for adults. However, more often it is used to get rid of the symptoms of dyspepsia:
- Discomfort.
- Nausea.
- Flatulence.
- Bloating.
- Non-infectious diarrhea.
- Heaviness in the stomach.
- Kolikov.
These symptoms generally occur as functional disorders as a result of overeating, intense physical activity, stress, climate change, introduction of new food.
Clinical trials of Trimedat on animals did not reveal any negative effects of the drug on the fetus, but there is still insufficient data on use in pregnant women. Prescription for this category of patients is possible only in the 2nd and 3rd trimester after assessment by a doctor potential benefits for mother and possible harm for the baby. Until the end of the 13th week, taking Trimedat is not recommended.
There is no data on whether trimebutine is able to penetrate into breast milk, therefore the drug is not prescribed to nursing women.
Contraindications
Trimedat tablets should not be taken by children under 3 years of age. Hypersensitivity to trimebutine or any auxiliary component is also a contraindication.
The drug should not be used during lactation and in the first 4 months of pregnancy.
Trimedat should not be taken by patients with other metabolic pathologies of this substance.
Applications and dosages
for adults
The tablets are intended for oral administration. They are washed down with water and swallowed without chewing. According to the manufacturer's recommendation, it is best to take Trimedat half an hour before meals. However, this requirement is not mandatory. If spastic pain occurs between meals, the medication can be shifted during this period.
The dosage of the drug does not depend on the disease for which it is taken, but differs for different age categories patients.
For adults and adolescents, Trimedat is prescribed 100-200 mg three times a day. The duration of treatment is determined by the doctor, taking into account the patient’s condition and the dynamics of improvement. For example, with irritable bowel syndrome, which often occurs in adults, the acute period of treatment requires taking 200 mg of the drug three times a day. Duration of therapy is about 4 weeks. After this, they switch to maintenance therapy, in which single dose Trimedata is halved. This treatment should be continued for about 3 months to achieve almost 100% cure.
It is allowed to take Trimedat for preventive purposes for certain diseases. For example, to prevent relapses of irritable bowel syndrome, you can take Trimedat 100 mg three times a day for 3 weeks.
When preparing for a study or operation, Trimedat is taken not as a course, but 1-2 times before the manipulation.
for children
A single dose depends on the age of the child and is:
- 6-12 years – 50 mg.
- 3-6 years – 25 mg.
To obtain such dosages, a 100 mg tablet is divided into 2 or 4 parts. A single amount is taken three times a day. The duration of therapy is determined by the doctor.
As an emergency aid (for dyspepsia), the drug is given in an age-specific dosage for several days and therapy is stopped after the symptoms of dyspepsia are eliminated. In the treatment of chronic functional disorders, Trimedat is taken for a long time, in several courses, with breaks between them of about 3 months.
for pregnant women and during lactation
Pregnant women should only be prescribed the drug by a doctor, individually assessing the required dosage and duration of the course. Treatment during and also during lactation is not allowed.
Side effects
Non-selectivity of action and influence on all peripheral opioid receptors creates increased likelihood appearance adverse reactions. The following complaints were noted from patients after taking Trimedat:
- Fatigue.
- Dizziness.
- Skin rash.
- Nausea.
- Violation menstrual cycle and soreness of the mammary glands.
- Unpleasant taste in the mouth.
- Dryness of the oral mucosa.
- Anxiety.
- Drowsiness.
- Urinary retention.
- Allergic reactions.
Interaction with other drugs
Interactions with drugs in official instructions not described, so Trimedat can be combined with other drugs.
special instructions
The dose of the drug should not be exceeded. To get rid of some pathological conditions a fairly long course of treatment is required, which includes maintenance therapy. Trimedat is an over-the-counter drug, so it may be the drug that will be in home medicine cabinet and be used by all family members.
Trimedat does not weaken the functioning of the central nervous system, therefore it does not exclude the possibility of control vehicle and other mechanisms.. This is a myotropic antispasmodic that relaxes the muscles of the gastrointestinal tract. The drug is available in tablets and extended-release capsules, which are contraindicated for children, pregnant and lactating women.
Drug price
The cost of the medicine is on average 401 rubles. Prices range from 198 to 743 rubles.
Gastrointestinal dysfunction is the most common health problem causing different symptoms And constant discomfort. You can get rid of pathology only by going through full treatment. However, during the period of therapy, it is recommended to take Trimedat or its analogues to eliminate the symptoms of the disease.
Comparative price table of analogues and substitutes
When counting average price, all forms of release were taken into account. The exact cost of drugs can be found in online pharmacies. Apteka.ru or Piluli.ru.
About the drug
The drug Trimedat is classified as symptomatic drugs groups of antispasmodics. It is recommended to take the medication for gastrointestinal disorders of a dyspeptic nature, as well as for severe nausea and frequent vomiting.
The dosage form of Trimedat is tablets. The medication contains trimebutine maleate in a dose of 200 mg. The drug is also produced in tablets for children.
The drug is indicated for the treatment of:
- gastroesophageal form of reflux disease;
- intestinal pathologies associated with its partial dysfunction.
Trimedat is prescribed in postoperative period patients suffering from intestinal obstruction. The drug is effective in eliminating the symptoms of intestinal and stomach dispersion, manifested in the form of flatulence, cramps, nausea, vomiting and other symptoms.
The drug is also used to prepare for diagnostic examinations for diseases of the gastrointestinal tract. Trimedat tablets are well tolerated by patients and have a minimum of contraindications. It is not advisable to take the medicine if there is a risk of the body reacting to the composition, as well as during pregnancy and breastfeeding. Tablets are not prescribed to children under three years of age. Violation of the rules for using Trimedat can lead to the appearance of an allergic-type dermatological reaction.
The medicine is produced in Russia. Its cost in pharmacies is from 400 rubles.
What drug should I replace Trimedat with?
Medicines for the treatment of diseases of the gastrointestinal tract are required individual approach Therefore, only the attending physician should select a drug for therapy.
Reviews about Timedat are mostly positive, however, the medication is not a cheap drug and may also be contraindicated for the patient. In such cases, analogues of Trimedat are prescribed.
With the consent of the doctor, it can be replaced with effective tablets Trimedat for drugs - antispasmodics with a similar effect:
- Neobutin;
- Motilium;
- Duspatalin;
- Ganaton.
Russian and foreign analogues in the majority have more high cost than the original product. Cheap substitutes do not have a complex effect, therefore, when choosing an analogue, you should study the annotation regarding the mechanism of action of the drug.
Neobutin
Substitute Trimedat with similar pharmacological properties– Neobutin. The drug affects the peristalsis of the intestines and stomach, preventing and eliminating abdominal pain, attacks of cramps and stool disorders.
Issues more cheap substitute Russia. Neobutin is the closest analogue, also containing trimebutin, but in more high dosage– 300 mg. The release form is the same - tablets.
A cheap analogue can be used rectally, orally and parenterally. Indications for use:
- manifestation of gastric and intestinal dispersion;
- pathologies of the biliary tract;
- disorder of gastrointestinal tract functions;
- the period after surgery on the abdominal organs in the epigastrium;
- preparation for endoscopy.
P It is not recommended to take cheap Neobutin tablets:
- nursing mothers;
- women bearing a child;
- children under three years old;
- people whose body does not tolerate the medicinal components of Neobutin.
After oral administration, the Trimedat analogue may cause allergic reaction. In exceptional cases, patients experience short-term fainting.
Neobutin is a cheaper medicine. Its price starts from 342 rubles.
Duspatalin
Among foreign analogues Trimedata is known for Duspatalin, produced pharmaceutical company Netherlands. The medicine is not cheaper than the original, but even more expensive. Its cost in rubles is from 450 – 700.
The analogue has antispasmodic properties and has a myotropic effect. The drug is prescribed to patients who have been diagnosed with diseases of the stomach and duodenum associated with increased contraction and tone muscle tissue organs.
Duspatalin is sold in capsule form with the content of the main component – mebeverine hydrochloride.
Despite the fact that the analogue is not cheap, its spectrum of action is quite narrow. Indications for treatment with Duspatalin are signs of spasticity or irritation of the abdominal organs:
- stomach ache;
- colic and spasms;
- bowel dysfunction;
- heartburn;
- gagging and nausea.
Overdose and the presence of contraindications can provoke side effects:
- constipation or diarrhea;
- allergies of various types;
- severe nausea;
- migraine.
If we talk about generics, it should be noted that Trimedat’s analogue, Duspatalin, in Russian pharmacies is cheaper than, for example, the German drug Ganaton (from 600 rubles).
Motilium
Another Russian substitute Trimedata - Motilium. The drug helps reduce muscle activity and normalize the functions of the gastrointestinal tract.
Unlike the cheaper Trimedat, Motilium is produced not only in tablet form, but also in the form of a suspension. The analogue contains a component that has the main effect - domperidone.
The list of indications for taking Motilium includes irritable bowel syndrome, which is accompanied by:
- flatulence;
- spasmodic attacks;
- sharp pain in the epigastrium;
- diarrhea.
When comparing Trimedat and Motilium, which is better, it is worth considering that the spectrum of action of the analogue is slightly greater than that of the original.
In addition to the treatment of IBS, Motilium is effective for gastrointestinal pathologies associated with indigestion, inflammation of the esophagus, and esophageal reflux. The analogue copes with the elimination of feelings of nausea and vomiting of various etiologies.
An adverse reaction may manifest itself as:
- depression;
- sleep disorders;
- increased anxiety;
- stool disorders;
- decreased lactation;
- hormonal disorders.
In connection even with minimal risk side effect the analogue is not prescribed to pregnant or lactating women, as well as to patients childhood less than 12 years and only when weighing more than 35 kg.
The list of contraindications includes the development of prolactinoma, cardiac pathologies, bleeding, perforation or mechanical obstruction in the gastrointestinal tract. The drug is not recommended for patients with substance intolerance medicinal composition and in case of kidney/liver failure.
The price for analogue is from 588 rubles.
Ganaton
The German analogue of Trimedat is designed to stimulate gastrointestinal motility. The drug is used as an antispasmodic and antiemetic agent in tablets based on itopride hydrochloride.
Ganaton is used for bloating, constipation, heartburn and frequent vomiting. Therapeutic effect is achieved with a course of taking the drug for pathologies of gastrointestinal diseases, manifested by:
- intestinal spasms;
- chronic feeling of overeating;
- lack of appetite;
- pain in the hypochondrium area;
- flatulence.
It is difficult to determine which is better Ganaton or Trimedat. The advantage of the substitute is more complex impact on the body. However, there is an analogue large quantity contraindications:
- internal bleeding in the abdominal cavity;
- age category of patients up to 16 years;
- organ damage due to perforation of organ walls;
- allergy to the composition;
- lactation period;
- any stage of pregnancy.
Side effect:
- tremor, frequent dizziness and severe headache;
- thrombocytopenia or leukopenia;
- allergy;
- stool disorder;
- jaundice.
The cost of Ganaton medicine is from 450 - 800 rubles.
Trimedat and analogues can be used as a single drug, as well as in combination with medications of other groups during a course of therapy. When replacing a drug with an analogue that is cheaper or, conversely, more expensive, you should consult your doctor.
