Powerful immunostimulant. Immunomodulators - a list of effective drugs for children and adults

Modern immunostimulating drugs are classified according to their origin into the following groups:

• Herbal remedies - extracts or tinctures of Echinacea, Eleutherococcus, Schisandra, Immunal, etc. These remedies have a mild adaptogenic and immunostimulating effect and are prescribed to patients with immunodeficiencies. When taken prophylactically, such drugs significantly reduce the risk of influenza or respiratory infections, they warn radiation pathology and reduce harm from cytostatics;
• Microbial preparations– Imudon, IRS-19, etc. The drugs act directly on macrophages and monocytes, which, after activation, intensively produce cytokines that trigger immune reactions, promoting the removal of microbes;
• Interferon agents – Anaferon, Viferon. The drugs protect the body from various kinds antigenic attacks of bacterial, viral and other origin;
• Synthetic drugs– Amiksin, Trekrezan, etc. Increase general organic resistance to negative external influence and stimulate immune responses;
• Endogenous agents – Thymogen, Timalin. These are drugs based on placental or bone marrow cells or thymus. They restore the normal number blood cells, cause increased interferon production and immune activity.

It is strictly not recommended to take drugs with adaptogenic or immunomodulatory activity on your own; the need for their use should be determined by an immunologist.

Popular drugs

Trekrezan (250 RUR*)

The adaptogenic immunomodulator Trecrezan stimulates interferon production, corrects and improves the patient's immune status. As a result of using the medication:

• Increases the body's endurance during mental and physical stress;
• Decreasing toxic effects various medications And chemical substances;
• The body becomes especially resistant to oxygen deficiency, temperature changes and other aggressive factors.

Thanks to such effects, Trekrezan is successfully used for therapeutic and prophylactic purposes for respiratory infections, flu or colds. In the presence of stressful influences (for example, lack of oxygen, hypothermia or overheating), it helps to increase the performance and resistance of the body.

This immunomodulator is prescribed for complex treatment alcohol withdrawal or heavy metal poisoning. The drug is contraindicated during pregnancy, children under 12 years of age and pregnant women with lactose intolerance.

Immunal, Echinacea (300 RUR*)

Immunal contains components plant origin(Echinacea juice). The drug provokes an increase in nonspecific immunity. By activating phagocytosis and increasing leukocytes, the drug inhibits reproduction and growth pathogenic microorganisms. In addition, Immunal has antiviral activity against herpes or influenza. The preparations Echinacea and Immunal are analogues, having the same active ingredient (extract from the Echinacea herb), so they have similar effect.

Both drugs are used:

1. Whenever initial signs influenza or colds, as well as for the prevention of these pathologies;
2. In order to improve the immune status in the process long-term treatment antibiotics;
3. In the treatment of recurrent genitourinary and respiratory pathologies.

Echinacea is contraindicated in autoimmune pathologies, immunodeficiency (HIV), AIDS, multiple sclerosis, hypersensitivity to the plant and its components, children under 12 years of age, in the presence of systemic pathologies such as leukemia, tuberculosis, etc. It is not recommended to take it unnecessarily and for pregnant women, because there are no definitive research results on the effect of the drug on the fetus and the course of pregnancy .

Immunal in the form of a solution is contraindicated for children under one year of age, and in tablets for children under 4 years of age. The drug should not be taken in case of autoimmune and systemic pathologies such as AIDS or HIV, multiple sclerosis and leukemia, tuberculosis, etc. Immunal should not be taken by persons who have hypersensitivity or intolerance to echinacea and other components of the drug. Unlike Echinacea, Immunal can be taken by nursing and pregnant women, but only with a doctor's prescription.

Immunomax (800 RUR*)

Effective immunostimulant, under the influence of which there is a threefold increase in the activity of the cellular structures of the immune system. Immunomax increases the body's resistance to viruses like herpes or plague, papillomavirus or parvovirus. In addition, the drug protects the body from bacterial microorganisms like chlamydia, staphylococcus, E. coli, salmonella or mycoplasma, ureaplasma, etc.

Immunomax contraindications:

• Up to 12 years of age;
• Breast-feeding and pregnancy;
• Hypersensitivity to the drug or its individual components.

The drug does not cause any adverse reactions. And in exceptional cases it can be prescribed during pregnancy.

Galavit (tablets RUR 300*, injections RUR 600*)

A modern immunomodulator, which is available in the form of suppositories, tablets and powder for injection solution. The medication has an additional anti-inflammatory effect. Galavit belongs to synthetic immunostimulants and is this moment has no analogues. The drug has a broad-spectrum effect:

1. It enhances the production of necessary antibodies;
2. Enhances the production of macrophages, which are distinguished by their ability to eliminate pathogenic pathogens;
3. Increases the production of interferons that promote resistance various infections;
4. Has an antioxidant effect;
5. It has hepatoprotective activity, i.e. it protects the liver.

Galavit is contraindicated for use in patients under 6 years of age, breastfeeding, pregnant women or people with intolerance of this medicine.

Arbidol (250 RUR*)

An antiviral agent with moderate immunomodulatory activity. The drug is indicated for diseases such as:

• ARVI, severe cases respiratory diseases complicated by pneumonic or bronchial processes, types of influenza A and B;
• Pneumonic lesions, complex treatment of chronic inflammation of the bronchi, recurrent herpes, pneumonia;
• Restoration and improvement of immune status, prophylactic administration of the drug after surgery;
• In the complex treatment of acute intestinal lesions rotavirus origin in pediatric patients (over 3 years).

The drug has virtually no contraindications and side effects. It is not prescribed to children under three years of age, as well as to patients hypersensitive to the drug. Possible side effects are very rare: allergic manifestations.

Isoprinosine (600 RUR*)

Tablet drug with antiviral and immunostimulating effects. Means synthetic origin, a purine derivative, is used for diseases such as:

1. Papillomavirus, including with lesions of the genital organs and larynx;
2. Various shapes ARVI and influenza;
3. Shingles and chickenpox;
4. Cytomegalovirus;
5. Various modifications of herpesvirus of all types, as well as herpetic keratitis, genital herpetic lesions, etc.;
6. Molluscum contagiosum;
7. Corey;
8. Mononucleosis infectious origin etc.

Among the disadvantages of the drug, patients note the presence of adverse reactions in the form of nausea and vomiting syndrome and epigastric pain, itchy skin, joint pain and dizziness, sleep disorders and headaches, exacerbations of gout or intestinal disorders. Since the drug causes an increase in urea in the blood, it is contraindicated in cases of urolithiasis, gout, insufficient renal activity and arrhythmia. In addition, Isoprinosine is contraindicated in children weighing less than 20 kg and under 3 years of age.

Imunofan (500 RUR*)

The drug Imunofan is an immunomodulatory drug with hepatoprotective, detoxification, antioxidant and immunostimulating activity. In addition, the drug prevents the occurrence of cellular resistance to antitumor drugs.

The drug is available in the form of injections, rectal suppositories or nasal spray. Imunofan is effective in treating:

• HIV infections;
• Various kinds immunodeficiency states;
• Papillomavirus;
• Cytomegalovirus;
• Viral hepatitis different types;
• Herpes;
• In complex antitumor therapy, etc.

The drug is not used in the treatment of children under 2 years of age and pregnant women with a Rhesus conflict with the fetus.

Tiloron (600 RUR*)

The medications Lavomax, Amiksin and Tiloram are analogues, have the same active ingredient (tilorone) and belong to the group of drugs - inducers of interferon synthesis, which have immunomodulatory and antiviral effects. The drugs are produced in tablet form.

1. Lavomax provokes an increase in the formation of antibodies, stimulates bone marrow stem cell structures, and reduces immunosuppressive activity. Used for herpetic and cytomegalovirus infections, viral hepatitis, respiratory and influenza infections in adult patients. Contraindicated for pregnant women, children and adolescents under 18 and breastfeeding women.
2. Amiksin has a similar effect and is able to stop viral reproduction. Can be used in pediatrics from the age of 7, however, it is contraindicated during breastfeeding and pregnancy.
3. Tiloram, like Lavomax, is contraindicated in patients under 18 years of age, pregnant and breastfeeding patients. Adverse reactions sometimes include allergic rashes, slight chills and dyspepsia (digestive disorders).

Timalin (500 RUR*)

The drug is produced in the form of a lyophilisate for the preparation of injection solutions. The active substance of the drug is thymus extract, which is obtained by extracting from the thymus gland of animals.

The drug is effective when it is necessary to restore immune activity. In addition, while taking Timalin, patients experience an improvement in cellular metabolic processes, hematopoiesis is restored and regeneration is accelerated.

Timalin is indicated:

• At reduced immune status against the background of various soft tissue and bone purulent-inflammatory pathologies;
• For infectious lesions of bacterial or viral origin;
• With inhibition of hematopoietic and immune functions against the background of chemotherapy or radiation treatment tumor and oncological processes, as well as during long-term antibiotic therapy, etc.

The drug has no contraindications and is not prescribed only to people with hypersensitivity to it. IN in rare cases The use of Timalin is accompanied by adverse allergic reactions.

There is an analogue based on the same substance - Taktivin.

Riboxin

It is a metabolic regulator and has antiarrhythmic and antihypoxic activity. As a result of taking the drug, blood circulation in the coronary network is normalized and the energy balance of the heart increases. Active substance– inosine. The drug is used only in adult patients in the treatment of myocardial ischemia and arrhythmia caused by taking cardiac glycosides.

Cytoflavin

Multicomponent preparation containing inosine, succinic acid, vitamins B₂ and PP. Cytoflavin is a metabolic drug that improves tissue nutrition, cellular respiration, and blood circulation. Has anti-ischemic and neuroprotective activity. Produced in tablets and injections, it is used in the treatment of patients of any age. It is not advisable to use in pregnant and lactating patients.

Can pregnant women take it?

Doctors do not have a clear opinion regarding the use of immunomodulators in pregnant women, however, the majority is inclined to believe that they should not be taken. Most of the funds in this group exist on pharmaceutical market relatively short-lived, so the long-term side effects of taking them are still unknown.

To increase immunity, it is better for pregnant women to adjust their diet, enriching it with vegetables, herbs and fruits, rationally organize their regime, spend more time walking fresh air etc.

In childhood

In the treatment of children, the use of immunomodulators and adaptogens is justified in the following cases:

• Frequent ARVI, colds and flu;
• In the absence of hyperthermic symptoms during respiratory infections and flu;
• For sleep disorders, severe weakness, frequent headaches;
• For food allergies;
• With a noticeable increase in lymph nodes.

Up to 1.5 years of age, immunomodulators are used only in exceptional cases. Older children, strictly according to medical indications, can be given immunomodulators of the interferon group. It is pointless to give specific names of such drugs, because only a pediatrician should prescribe them. As immunostimulants and adaptogens in children, it is better to use natural remedies such as honey, rose hips, garlic or onions, eucalyptus, etc.

General operating principles

Immunomodulatory drugs are intended to balance the level of cellular structures of the immune system in the presence of autoimmune pathologies. These drugs balance the activity of all immune components, if necessary, suppressing their activity or activating it. The action of adaptogens is aimed at increasing the resistance of organic structures to infectious, viral and other types of external influences.

Immunomodulatory drugs are prescribed to patients with serious health problems. There are a number of pathologies against which the body is unable to resist even the simplest infectious lesions. The most famous similar pathology is a human immunodeficiency virus. To avoid constant colds and influenza with any minor hypothermia, such patients are prescribed immunomodulators.

Premature babies also need immunomodulatory therapy, especially when they begin to attend preschool educational institutions. In such a situation, children find themselves in a completely new environment that has its own bacteria and microorganisms, so sometimes during the adaptation period children are prescribed adaptogens, which:

1. Has little effect on nervous system structures;
2. Restore endocrine activity;
3. Accelerate material exchange reactions;
4. Form the body's resistance to adverse external influences;
5. Helps improve performance and tolerance excessive loads etc.

At the same time, adaptogenic drugs do not disrupt the processes of normal functioning of the body. They are recommended to be taken by workers in hazardous industries and hard work, athletes and people in a state of stress or depressive disorder. If you take adaptogens during increased mental and physical stress, the drugs will accelerate the body's adaptation without harm to brain and muscle activity.

Immunostimulating agents are designed to regulate the body's defenses. Due to a number of diseases, the human immune system does not work properly and does not perform all its functions.

These drugs were invented to help the body’s immune system self-heal. Many of the immunomodulatory agents have antiviral effect, and most often they are prescribed when a person suffers from ARVI several times a year.

It should be noted that medical practitioners have different attitudes towards immunomodulators. Some see good use in them, while others consider their use useless. You can also find different opinions among patients. To evaluate these drugs, let's look at the most popular immunomodulatory drugs today.

Effective immunomodulatory agents

Lycopid

The drug is used in complex treatment regimens for patients. The main indications for its use are: viral hepatitis, herpes, various secondary immunodeficiencies, purulent-inflammatory processes, tuberculosis, psoriasis and others.

The medicine has a powerful effect, therefore it is indicated for both treatment and prevention. Lykopid has cytotoxic activity, exhibits bactericidal properties, and promotes the resorption of small tumors.

1. The drug is available in tablets. The course of treatment depends on the severity of the disease.
2. IN pediatric practice Likopid is recommended for use from three years of age. In some cases, under the supervision of a doctor, the drug can be used for a child starting from one year of age.
3. In pediatrics, only one dose is allowed - 1 mg per day. For adults, the dose of the drug can vary, reaching up to 20 mg per day.

Pregnancy and lactation are contraindications for use.

The price for Lykopid (1 mg tablets No. 10) is around 230 rubles. For a dosage of 10 mg No. 10 you will have to fork out more; the cost for such a lycopid will be about 1,700 rubles.

Immunal

Immunal contains echinacea. The plant has antiviral, antibacterial, regenerating and anti-inflammatory effects.

Immunal is prescribed for influenza, ARVI, herpes, gynecological problems, secondary immunodeficiencies. In minimal doses it is used to maintain normal operation immunity.

Contraindications to the use of Immunal are:

• tubinfection,
• rheumatoid arthritis,
• leukemia,
• allergic reactions,
• various systemic pathologies.

During pregnancy and lactation, the drug is acceptable in extreme cases.

Immunal is produced in tablets, drops, powder, and solution. The doctor selects the necessary form for treatment or prevention.

The price for Immunal (Slovenia) in tablets (No. 20) is 300-350 rubles.

Drops are offered for the youngest patients (from 12 months). Tablets are recommended no earlier than 4 years of age. Some pediatricians believe that it is preferable to use immunostimulating drugs in tablets only after 12 years. Dosing of the drug is carried out according to the instructions.

Kagocel

The drug has antiviral and immunomodulatory effects. Kagocel is similar in action to interferon. It is used to treat ARVI and herpes. Recommended for use from the age of three. Plus Kagocel - minimal possible side effects ( individual intolerance and allergic reactions).

Depending on age and disease, the dose of the drug varies.

Kagocel (Russia) is available in tablets. The price per package (No. 10) is an average of 260 rubles. A course of treatment usually requires 10-18 tablets. Treatment of herpes will cost more, approximately 780 rubles.

Viferon

This drug acts comprehensively. The active substance is human recombinant interferon alpha-2. The product has the following properties: immunomodulatory, protective, antiviral, antiproliferative.

The range of applications for Viferon is quite diverse. These are ARVI, viral lesions of mucous and skin surfaces, stenosing laryngotracheobronchitis (in complex therapy), herpes, viral hepatitis, HIV, bronchial asthma, and others.

Viferon has also found widespread use in pediatrics. It is used even in newborns and premature babies.

Depending on the form of the drug, the dose of Viferon has its own characteristics. For example, suppositories are used 1-2 times a day, and gel up to 5 times a day.

The price for Viferon is as follows:

• gel 36000IU/ml 10ml costs about 180 rubles;
• suppositories 1000000IU (No. 10) - 520 rubles;
• ointment 40000IU/g 12g - 180 rubles.

In principle, Viferon can be classified as an inexpensive drug, which makes it popular among patients.

Amiksin

This drug, like many drugs with antiviral and immunomodulatory properties, is an inducer of interferon synthesis. It is used for liver diseases, acute respiratory viral infections, tubinfection and other diseases. It has been noted that amiksin is useful for urological, gynecological and neuroinfections.

The dosage of the drug is determined only by the doctor, because amixin is prescribed differently depending on the day of therapy.

Amiksin has few side effects: allergic reactions, chills, diarrhea.

In pediatrics, the drug is used only from the age of seven. The drug is not prescribed to pregnant women and persons with individual intolerance to the composition of amixin.

Tablets of 60 or 125 mg are available. The price of tablets (60 mg, No. 10) is 550 rubles.

Cycloferon

The drug is an inducer of endogenous interferon. Exhibits antiviral, immunomodulatory, antitumor, anti-inflammatory effects. Cycloferon reduces the content of carcinogens in the blood, and also helps to slow down metastatic processes in malignant neoplasms.

The effectiveness of cycloferon has been proven for hepatitis, HIV, ARVI, herpes, enteroviruses, chlamydia, tick-borne encephalitis and other infections. At systemic diseases Cycloferon exhibits moderate analgesic and anti-inflammatory effects.

The method of application depends on the severity infectious process(follow the instructions for use).

Contraindications: individual intolerance, allergies, pregnancy, lactation and liver cirrhosis. In pediatrics, the drug is used from 4 years of age.

Cycloferon is available in tablets, liniment and solution for injection. The price, respectively, is 190 rubles (10 tablets), liniment - 105 rubles, ampoules (5 pieces) - 330 rubles.

Thymogen

The drug belongs to the drugs that correct and stimulate the immune system.

The basis of thymogen is glutamine tryptophan. Immunodeficiency conditions - indications for use of this product. No special contraindications or side effects were found.

Thymogen has three dosage forms: aerosol, injection solution, cream for external use.

The price of the drug depends on dosage form. Injection solution 0.01% 1 ml No. 5 costs about 330 rubles. The price of cream for external use 0.05% 30g ranges from 270 to 330 rubles. Aerosol 0.025% 10 ml costs about 310 rubles.

Derinat

This drug has established itself as a powerful immunomodulator. The range of its applications is huge. These are oncological processes, chronic gastrointestinal diseases, cardiac pathologies, tubinfection, gynecological and urological infections.

Derinat activates all parts of the immune system and also stimulates regenerative processes. Thanks to derinat, tissue regeneration occurs faster, so this product is prescribed for the treatment of burns and ulcerative processes on the skin.

Dystrophic problems in eye diseases are eliminated faster when taking Derinat.

A big advantage of this remedy is the possibility of its use from the first days of a child’s life, when many medications are contraindicated.

Derinat is available in solution for injection or solution for local and external use.

The course of treatment depends on the disease and can range from 5 to 45 days. In any case, derinat treatment is not carried out independently.

Solution 0.25% 10ml for local application costs about 300 rubles, injection solution 1.5% 5 ml No. 5 - 2000 rubles.

Anaferon

The effectiveness of anaferon has been noticed in acute respiratory viral infections, bronchopulmonary pathologies, herpetic infection, as well as other diseases caused by viral agents. Anaferon is safe homeopathic medicine, which has high antiviral protection. Bacteria, like viruses, also lose their strength thanks to the “work” of anaferon. Diseases with chronic immunodeficiency are a direct indication for this drug.

Like other immunomodulators, anaferon should not be used during gestation, but if particularly necessary, it can be used in the second and third trimester of pregnancy. This is due to the fact that after the 12th week of pregnancy the fetus is already more protected. Passed embryonic period, the placenta became thicker, and future baby started typing more active mass bodies.

In pediatrics, anaferon is used once a day. As a rule, the course of treatment lasts a week. Sold in pharmacy chain children's anaferon(in drops and tablets). The form of the drug for therapy is selected by the doctor.

The price for children's and adult anaferon in lozenges (20 pieces) is about 200 rubles, in drops (25 ml) a little more expensive - 250-300 rubles.

Cheap analogues of Anaferon - list.

Lysobacter

The drug is popular in otolaryngology and dentistry. It is based on two active components- lysozyme and vitamin B6. The first fights infection, the second protects the mucous membrane. Despite the fact that lysobact is an antiseptic, its effectiveness in the fight against viruses has been proven more than once. The immunomodulatory effect of lysobact is weak, so it can be safely used during gestation and lactation.

Lysobact is prescribed for infections and inflammation of the pharyngeal space, stomatitis, gingivitis, aphthous ulcerations, and herpes.

Side effects when taking lyzobact appear extremely rarely. Only mild allergic reactions are possible.

The course of treatment lasts about 8 days. The tablets are dissolved slowly under the tongue (sublingually). It is advisable to keep the dissolved mass under the tongue for as long as possible and refrain from eating food and water for several hours.

Tablets are used from 3 to 8 pieces per day. Children from 3 to 7 years old are recommended to take 1 tablet three times. For adults, the following dosage is recommended - 2 tablets 4 times a day.

The price of lyzobact (Bosnia and Herzegovina) No. 10 is 250-320 rubles.

Remantadine

Conclusion

Analyzing our article, it is easy to notice that many drugs have much in common. This is especially true for indications for use. To date, there is still a lot of controversy regarding the use of immunomodulators. There are opinions that the body itself is capable of recovering, and immunomodulators act only as a placebo.

Let's look at the options for immunomodulators, list effective drugs for colds, the prices of which depend on the region.

Injection solutions: “Neovir”, “Altevir”, “Reaferon EC”, “Ridostin”, “Ingaron”, “Cycloferon”, “Timogen”, “Erbisol”, “Timalin”.

Powder: "Reaferon EU".

Immunostimulants for children

The child’s immunity is in the process of formation; any interventions that are not justified by extreme necessity can only do harm. Until the age of one, it is better not to know what immunomodulatory drugs are; they are prescribed only for severe diseases. The formation process itself defense mechanisms occurs as a response to viruses and bacteria. Therefore, you should not immediately grab the pills; it is important to follow this natural path.

It is preferable to strengthen the body and restore strength with natural products, after making sure that there is no allergic reaction. For children over 1 year of age, manufacturers are developing convenient forms and acceptable dosages, for example, “Tsitovir-3” in the form of syrup or powder for the preparation of a suspension is prescribed to frequently ill children during the period of ARVI.

Only a doctor should make appointments. For this reason, we do not provide detailed descriptions and ratings of children's immunomodulators or drug names. Self-medication is unacceptable here; it is very easy to break the fine line, and recovery may take years.

Our health depends on many factors. Despite the fact that the properties of immunity have not been fully studied, it plays one of the main roles.

Uncontrolled use of medications, stress, and lack of sleep have a great impact on the functioning of the immune system. Its formation, maintenance, restoration is a long painstaking work of nature, medicine and, of course, man himself. For many decades, science has been studying immunomodulators and their effect on the body, creating more and more advanced drugs. The main task is to do our best to help preserve the natural protective mechanisms inherent from birth and strengthen them.

Monitor the well-being and health of your loved ones with Tsitovir-3.

Only 30% of newborns have absolute health. Most children have some kind of disorder, often associated with reduced immunity. In order to strengthen the body's defenses and prevent diseases from the first months of life, the doctor may recommend special medications.

Immunomodulators for children - means that increase immunity. They come in several types, and the list of drugs includes both herbal and artificial ones. Immunomodulatory drugs can be prescribed from the first month of life, but there are few such drugs, but for children from 2 years of age there are already wide choose medicines.

Immunomodulators change the number of immune cells up or down. Immunostimulants activate immune protection, they are prescribed when necessary to strengthen the protective reaction of the human body. They belong to the group of immunomodulators.

Immunostimulants are more often prescribed for HIV, AIDS, frequent infectious diseases, which complements the effect of antiviral tablets. Immunomodulators, which reduce the number of immune cells, are used to treat autoimmune processes, allergies, and neoplasms. Each group of drugs contains cheap and effective drugs that are suitable for children of different ages.

Operating principle

Immunostimulating drugs for children of different origins have a different mechanism of action on the body. The medicine is selected individually, because taking it triggers a number of reactions that can affect the functioning of all systems. In this regard, the decision to take immunostimulating drugs is made by the doctor, and only he prescribes the dosage, dosage regimen and duration of treatment.
How do medications that enhance immunity work:

• microbial origin- influence phagocytes, stimulate the immune response;
• immunoglobulin groups- fight specific types of pathogens;
• thymic origin- influence T-lymphocytes, enhancing their activity and production, and have an antioxidant effect;
• based interferons- activate the production of natural interferon;
• synthetic origin- enhance the production of antibodies and interferon A and B, enhance the activity of macrophages and neutrophils, inhibit the reproduction of viruses;
• interleukins group- compensate for the lack of interleukins.

Types of immunostimulants

Immunostimulants are classified not only by origin, but also by strength. There are strong and mild drugs. The first group is used in complex therapy for severe diseases - HIV, oncology, herpes virus.

Mild-acting immunostimulants are prescribed from 6 months. Immunomodulators for children over 3 years of age can be used for the purpose of prevention seasonal diseases and for the treatment of already formed infections.

Vegetable origin

Among the best immunomodulators for children of plant origin are: Bioaron C and Immunal. This group includes medicines based on ginseng extracts, Chinese lemongrass, chokeberry.

Bioaron S effectively protects the child from influenza and colds, reduces the likelihood of bacterial complications and shortens the recovery period. It contains vitamin C, aloe extract, chokeberry juice.

Indications for its use include acute respiratory pathologies, the period after treatment of bacterial infections, and the prevention of seasonal diseases. A doctor may prescribe the drug in the complex treatment of colds and infections when there is a risk of complications. The medicine also helps children with decreased appetite.

Bioaron S is used from the age of 3 years. The standard dosage is 2 times a day, 5 ml for 2 weeks. The immunostimulant is diluted in 20 ml of warm boiled water. In case of lack of appetite, the medicine is taken once immediately before meals.

Bioaron S is contraindicated for acute inflammatory diseases digestive system, up to 3 years, with increased sensitivity to the components in the composition. Adverse reactions include allergies, nausea, heartburn, and vomiting.

The drug Immunal contains echinacea juice. It exhibits immunostimulating activity. Its action is directed against herpes and influenza viruses. Prescribed for the treatment and prevention of colds.

The instructions for use for children indicate that Immunal is prescribed 1 tablet up to 4 times a day. It is recommended to take it for 10 days, repeat course possible in 2 weeks. In the form of drops, the immunostimulant is indicated 3 times a day, 2.5 ml. It is recommended to start treatment as soon as the first signs of a cold appear.

Immunal is contraindicated with hypersensitivity to the drug and severe systemic diseases. Tablets are not prescribed for pathologies of the hematopoietic organs, oncology, primary immunodeficiency, diathesis of allergic origin.

Adverse reactions of Immunal will include stomach pain, nausea, leukopenia, itching, rash, hyperemia, dizziness, decreased blood pressure. From the outside nervous system The child may experience insomnia and an excited state.

Artificial origin

Synthetic immunostimulants include Dekaris, Dibazol, Levamisole, Diucifon. These are low molecular weight drugs. Polyoxidonium is a high-molecular compound. It not only activates various parts of the immune defense, but also has an antioxidant, membrane-protective and detoxifying effect.

Local and general preparations

Immunostimulants can be used orally and locally. A good antiviral immunomodulatory agent to increase local immunity There will be Imudon, which is prescribed for dental and ENT diseases.

Treatment with any medications, regardless of the method of administration, is carried out under the supervision of a physician. To determine health status, diagnostics include lab tests And instrumental studies. The use of immunostimulating drugs for children in the form of lozenges is usually prescribed when the child is already able to understand how to take the medicine.

To immunostimulants general action include interferons, stimulants, bacterial and other agents that are prescribed for oral administration.

When is taking immunomodulators justified?

Immunostimulating agents for children are prescribed when signs of reduced immunity are observed and when immunodeficiency is diagnosed. Treatment with tablets from 1 year is considered after confirmation of a violation of the immune system. The reason for early screening there will be a child severe course pregnancy.
Signs of reduced immunity in a child will be:

• frequent seasonal diseases (from two times per season);
• the temperature does not increase during infectious diseases;
• the child is worried about general weakness, constant fatigue, insomnia;
• frequent allergic manifestations;
• peeling skin, brittle nails, poor hair growth;
• enlarged lymph nodes.

Rating - the best immunomodulators and immunostimulants for children

The best immunostimulating drugs for children have a small list of adverse reactions and are safe for long-term use. Each medicine has age restrictions and contraindications. The list of effective drugs for children includes Derinat, IRS 19, Anaferon for children, Viferon, Aflubin, Laferobion, Groprinosin, Ribomunil Grippferon. Some of them are also indicated for treatment during pregnancy.

Derinat

Local antiviral immunostimulating drug in the form of nasal drops. Used for the prevention of colds, seasonal diseases and the treatment of acute respiratory viral infections. It helps improve cellular and humoral immunity, increases immunity to pathogens. The good thing about this medicine is that it can be prescribed from the first months of life. Compared to the drugs Grippferon and Ferrovit, it is more effective.

IRS 19

Used in the form of a spray, it is a complex immunostimulant for combating pathogens of respiratory diseases. Prescribed to stimulate the protective mechanisms of the respiratory tract. The immunostimulant activates phagocytosis, increases the production of antibodies, interferon and lysozyme.

Indications for use in children are laryngitis, rhinitis, pharyngitis, otitis media, tonsillitis, influenza, ARVI, allergic bronchial asthma. There is a risk of adverse reactions in the first days of use in the form of a runny nose. May occur less frequently allergic symptoms.

Anaferon for children

Children's Anaferon blocks the spread of viruses and activates immune defense. This double action allows you to influence the disease comprehensively. The immunostimulant has a good antiviral effect. It can be used from the second month of life. Anaferon is safe for children of any age and can be prescribed for both treatment and prevention.

Indications for use will be ARVI, influenza, herpes virus, cytomegalovirus, immunodeficiency conditions, bacterial infections in complex therapy. The medicine may cause allergies.

Viferon

Viferon in the form of rectal suppositories can be used for newborns. It has several effects - antiviral, antiproliferative, immunostimulating. The medicine is used for ARVI, hepatitis, infectious and inflammatory diseases.

The child may have increased sensitivity to the components in the composition, then Viferon does not apply. Adverse reactions may include rashes, allergies, and itching.

Aflubin

Aflubin is a homeopathic immunostimulant in the form of tablets and drops. Both forms of the immunostimulant simultaneously have analgesic, anti-inflammatory, immunostimulating, antipyretic and detoxifying effects.

Aflubin is indicated for influenza, respiratory tract infections, acute respiratory viral infections, and inflammatory pathologies of the ENT organs. Taking the medicine may cause increased salivation.

Laferobion

Children under 3 years of age are prescribed Laferobion at bacterial infections, herpes, hepatitis. It comes in spray form. Has antiviral, antitumor, immunostimulating effects.

Adverse reactions may include flu-like symptoms. Uncontrolled use of the medicine can cause disorders in many organs, so treatment is always supervised by a doctor.

Groprinosin

Renders direct antiviral effect. Stimulates the production of interferon, activates the synthesis of cytokines. Renders complex action on the immune system. It is used to reduce the viral load in diseases such as bronchitis, influenza, parainfluenza, ARVI, mumps, Epstein-Barr virus, measles.

The medicine is contraindicated in urolithiasis. In rare cases, children experience nausea, loss of appetite, constipation, diarrhea, and stomach pain. At long-term use there is a risk of sleep disturbances, arthralgia, and skin rashes.

Ribomunil

In tablet form, Ribomunil acts like a vaccine. It can be used from 6 months. The medicine contains identical bacterial antigens and increases humoral and cellular immunity.

Ribomunil is prescribed for recurrent diseases of the respiratory tract and ENT organs, bronchial asthma, chronic bronchitis. The medicine helps with long-term inflammatory processes nasopharynx and larynx. Has few adverse reactions. Nausea, allergic reactions, diarrhea, and vomiting occur extremely rarely.

Grippferon

The combined drug Grippferon can be used for infants. It is obtained synthetically without the use of donated blood, which makes it safe. The medicine immediately reaches the site of pathology and exhibits activity against pathogenic microorganisms. The drug enters the general bloodstream in small quantities, so the risk of adverse reactions is practically eliminated.

Possible harm and adverse reactions

Drugs that affect the immune system affect the functioning of internal organs. They are potentially dangerous means, because their incorrect use can lead to reverse effect. According to reviews, the medications are well tolerated by children, and unpleasant symptoms appear due to wrong combination or ignoring the rules of admission.

Possible adverse reactions from taking immunostimulants:

• bacterial - well tolerated, in rare cases can cause nausea, dyspepsia, diarrhea, allergic symptoms;
• herbal - extremely rarely, severe allergic manifestations, low blood pressure, skin rash, bronchospasm are possible;
• thymic - allergies, nausea, dizziness, increased body temperature, exacerbation of inflammatory processes;
• interferons - flu-like syndrome, allergies;
• cytokines - allergies;
• synthetic - exacerbation of chronic diseases, allergies, pain in the injection area during injection;
• immunoglobulins - allergic symptoms, changes in blood pressure, nausea, fever.

Immunostimulating agents affect the structure of DNA. Taking them unnecessarily can significantly harm the child’s body. The consequence may be depletion of the immune system.

You should not use this group of products for children at the first sign of a cold, because there are more for this purpose. safe drugs. The decision to take immunostimulants is made by the doctor based on the results of a blood test and immunogram.

There are a number of pathologies for which the use of these drugs is strictly prohibited. These include autoimmune hepatitis, cirrhosis, diabetes, some forms of asthma.

If symptoms of reduced immunity appear, parents and their child should contact a pediatrician or immunologist. The specialist will conduct research and be able to prescribe effective treatment. While taking the medication, the doctor will monitor the child’s condition, and if adverse reactions occur, he will discontinue the immunostimulant.

Immunomodulators are a group of pharmacological drugs that activate the body’s immunological defense at the cellular or humoral level. These medications stimulate the immune system and increase nonspecific resistance body.

main organs of the human immune system

Immunity - unique system of the human body, capable of destroying foreign substances and requiring proper correction. Normally, immunocompetent cells are produced in response to the introduction of pathogenic biological agents into the body - viruses, microbes and other infectious agents. Immunodeficiency states are characterized by decreased production of these cells and are characterized by frequent morbidity. Immunomodulators are special drugs combined common name and a similar mechanism of action used for the purpose of prevention various ailments and strengthening the immune system.

Currently, the pharmaceutical industry produces great amount agents that provide immunostimulating, immunomodulating, immunocorrective and immunosuppressive effect. They are freely sold in pharmacy chains. Most of them have side effects and provide negative impact on the body. Before purchasing such medications, you should consult your doctor.

• Immunostimulants strengthen the human immune system, ensure more efficient functioning of the immune system and provoke the production of protective cellular components. Immunostimulants are harmless for persons who do not have immune system disorders and exacerbations of chronic pathologies.
• Immunomodulators correct the balance of immunocompetent cells in autoimmune diseases and balance all components of the immune system, suppressing or increasing their activity.
• Immunocorrectors have an effect only on certain structures of the immune system, normalizing their activity.
• Immunosuppressants suppress the production of immune components in cases where its hyperactivity causes harm to the human body.

Self-medication and inadequate medication use can lead to the development autoimmune pathology, while the body begins to perceive its own cells as foreign and fight against them. Immunostimulants should be taken according to strict indications and as prescribed by the attending physician. This is especially true for children, because they the immune system fully formed only by the age of 14.

But in some cases, you simply cannot do without taking drugs from this group. At serious illnesses with a high risk of developing serious complications taking immunostimulants is justified even in children and pregnant women. Most immunomodulators are low-toxic and quite effective.

Use of immunostimulants

Preliminary immunocorrection is aimed at eliminating the underlying pathology without the use of drugs basic therapy. It is prescribed to persons with diseases of the kidneys, digestive system, rheumatism, and in preparation for surgical interventions.

Diseases for which immunostimulants are used:

1. Congenital immunodeficiency,
2. Malignant neoplasms,
3. Inflammation of viral and bacterial etiology,
4. Mycoses and protozooses,
5. Helminthiasis,
6. Kidney and liver pathology,
7. Endocrinopathology - diabetes mellitus and other metabolic disorders,
8. Immunosuppression while taking certain medicines- cytostatics, glucorticosteroids, NSAIDs, antibiotics, antidepressants, anticoagulants,
9. Immunodeficiency caused by ionizing radiation, excessive alcohol intake, severe stress,
10. Allergy,
11. Conditions after transplantation,
12. Secondary post-traumatic and post-intoxication immunodeficiency states.

Presence of signs of immune deficiency - absolute reading to the use of immunostimulants in children. The best immunomodulator Only a pediatrician can choose for children.

People who are most often prescribed immunomodulators:

• Children with weak immune systems
• Elderly people with weakened immune systems,
• People with a busy lifestyle.

Treatment with immunomodulators should be under the supervision of a physician and immunological research blood.

Classification

The list of modern immunomodulators today is very large. Depending on their origin, immunostimulants are distinguished:

Independent use of immunostimulants is rarely justified. They are usually used as an adjunct to the main treatment of pathology. The choice of drug is determined by the characteristics of immunological disorders in the patient’s body. The effectiveness of drugs is considered to be maximum during exacerbation of the pathology. The duration of therapy usually varies from 1 to 9 months. Using adequate doses of medication and correct observance treatment regimen allows immunostimulants to fully realize their therapeutic effects.

Some probiotics, cytostatics, hormones, vitamins, also have an immunomodulatory effect. antibacterial drugs, immunoglobulins.

Synthetic immunostimulants

Synthetic adaptogens have an immunostimulating effect on the body and increase its resistance to unfavorable factors. The main representatives of this group are “Dibazol” and “Bemitil”. Due to their pronounced immunostimulating activity, the drugs have an antiasthenic effect and help the body quickly recover after prolonged exposure to extreme conditions.

For frequent and prolonged infections with prophylactic and therapeutic purpose combine Dibazol with Levamisole or Decamevit.

Endogenous immunostimulants

This group includes preparations of thymus, red bone marrow and placenta.

Thymic peptides are produced by thymus cells and regulate the functioning of the immune system. They change the functions of T-lymphocytes and restore the balance of their subpopulations. After the use of endogenous immunostimulants, the number of cells in the blood is normalized, which indicates their pronounced immunomodulatory effect. Endogenous immunostimulants enhance the production of interferons and increase the activity of immunocompetent cells.

• "Timalin" has an immunomodulatory effect, activates regeneration and repair processes. It stimulates cellular immunity and phagocytosis, normalizes the number of lymphocytes, increases the secretion of interferons, and restores immunological reactivity. This drug is used to treat immunodeficiency conditions that develop against the background of acute and chronic infections, destructive processes.
• "Imunofan"- a drug widely used in cases where the human immune system cannot independently resist the disease and requires pharmacological support. It stimulates the immune system, removes toxins from the body and free radicals, has a hepatoprotective effect.

Interferons

Interferons increase the nonspecific resistance of the human body and protect it from viral, bacterial or other antigenic attacks. The most effective drugs that have a similar effect are "Cycloferon", "Viferon", "Anaferon", "Arbidol". They contain synthesized proteins that push the body to produce its own interferons.

Naturally occurring drugs include leukocyte human interferon.

Long-term use of drugs in this group minimizes their effectiveness and suppresses a person’s own immunity, which ceases to function actively. Inadequate and too long-term use of them has Negative influence on the immunity of adults and children.

In combination with other medications, interferons are prescribed to patients with viral infections, laryngeal papillomatosis, cancer. They are used intranasally, orally, intramuscularly and intravenously.

Preparations of microbial origin

Medicines in this group have a direct effect on the monocyte-macrophage system. Activated blood cells begin to produce cytokines, which trigger innate and acquired immune responses. The main task of these drugs is to remove pathogenic microbes from the body.

Plant adaptogens

TO plant adaptogens include extracts of echinacea, eleutherococcus, ginseng, and lemongrass. These are “mild” immunostimulants, widely used in clinical practice. Drugs from this group are prescribed to patients with immunodeficiency without a preliminary immunological examination. Adaptogens trigger the work of enzyme systems and biosynthetic processes, and activate the body’s nonspecific resistance.

The use of plant adaptogens for prophylactic purposes reduces the incidence of acute respiratory viral infections and, resists the development of radiation sickness, weakens toxic effect cytostatics.

For the prevention of a number of diseases, as well as for get well soon Patients are advised to drink daily ginger tea or cinnamon tea, take black peppercorns.

Video: about immunity – School of Dr. Komarovsky