Endometrium after unsuccessful IVF. Reasons for failure after the IVF procedure

In 1973, Carl Wood's group at Monash University (Australia) achieved the first IVF pregnancy. The researchers artificially fertilized the egg and transferred the embryo into the uterine cavity. Unfortunately, after a few days the body rejected the injected material naturally.

We will never know the feelings of a woman who decided to be an experimental subject in those conditions. Perhaps she was pre-prepared for a negative result and was not upset. Or maybe these experiments were her last hope to give birth to a child. After all, one can become a “guinea pig” only out of despair.

One way or another, the first IVF ended in failure for her personally, although for medicine as a whole it was a giant step forward. Since then technology in vitro fertilization is being improved continuously, but the result is still far from 100%. The Monash University Clinic continues to deal with IVF, with patients becoming pregnant in 31% of cases when “fresh” five-day-old embryos are implanted and in 34% of cases when thawed after. One of the most famous clinics in Ukraine, “Implant” in Kharkov, gives a percentage of 37%. And these are leaders in their industry. That is, in fact, two out of three women languish for two weeks waiting for two lines on the test in vain.

In vitro fertilization is a big financial, mental and physical cost. When they don’t lead to success, disappointment lurks around the corner: in yourself, your partner, technology, doctors, others... The list goes on and on. Depression may follow disappointment. Therefore, it is very important to go into the protocol well prepared not only physically, but also mentally. Awareness of the percentage of possible success allows, in case of failure, to perceive it not as the end of the world, but just as one of the steps towards achieving a dream - having a child.

But no matter how prepared a woman is for negative result, in any case, this will become a serious test for her and those around her. Therefore, rehabilitation is necessary.

Need rehabilitation:

• woman's body;
• her psyche;
• family relationships.

In addition, it is necessary to develop a plan for further action:

• understand the possible reasons for failure;
• if the cause is found, then eliminate it;
• change clinic or doctor if necessary;
• try again.

Unfortunately, such a plan is relevant if there is a financial opportunity. However, do not despair: the probability natural pregnancy after unsuccessful IVF reaches 24% (according to French Institute INSERM). The author of the article personally knows a woman who became pregnant through a cycle after two “flight” IVF protocols.

• Rehabilitation of the bodily component

As is known, in healthy body – healthy mind. During physical exercise adrenaline and endorphin are produced - the so-called “happiness hormone”. Therefore, sport will help to put in order not only the body, but also the psyche. In addition, training brings variety to life and forces you to leave the apartment, which is important when depressive states. Regular exercise will help you get rid of extra centimeters that may have appeared during the IVF protocol or during the depressive eating of sweets near the TV. Anything will do - from cycling to... group classes at your nearest fitness center. The main thing is regularity and a clear goal.

Don't forget about reproductive health. Exactly It is often possible to find out exactly what is wrong. The woman should go to the doctor conducting the protocol and discuss possible reasons for failed IVF. We'll have to retake some tests. May be required exploratory operation. Developing a plan for further examination is a good chance to improve your mood.

Changing your lifestyle will also help. It’s worth reviewing your diet, going on a diet if necessary, making adjustments to your daily schedule, and just taking care of yourself - visiting a cosmetologist and stylist.

• Rehabilitation of soul and spirit

It’s good if a woman has a trusting relationship with a close relative or friend: psychological assistance and support can be found from them. It’s better not to contact your husband with this problem -. If there is no one to turn to in your immediate environment, then the path lies to the office professional psychologist or in a support group where women with a similar problem gather, real or virtual - it doesn’t matter. In any case, if there are signs of depression or apathy, it is better not to let it go and start correcting the situation.

If IVF fails, not only the woman, but also the husband is the victim. Very rare couples during the protocol (and many long before it) manage not to look at sex as medical manipulation. Intimate relationships on certain days, the eternal wife and her tears every month, the pills on the table are also not conducive to love affairs. At some point, a man feels like just some kind of appendage to a woman, serving exclusively to fulfill reproductive function. And now - another “flight”, and a very critical one, judging by the upset of the wife. Of course, from a woman’s point of view, after such a fiasco, it is she who should be caressed and warmed by her strong “half.” Flowers and other signs of attention - everything to bring her out of her stupor. Alas, in real families usually everything is exactly the opposite. The wife closes herself off from the whole world in her grief, and the husband is left without affection, ironed shirts and hot borscht for lunch. A woman must clearly understand that this particular period of time may be the beginning of the end of the family, and make efforts to prevent such a turn of events. After all, you need very little - a morning smile, a lovingly prepared dinner, a trip to the cinema together or just for a walk. Those whose marital bonds have weakened even before the in vitro fertilization procedure can take advantage of the failure and “reset” the relationship. There will always be time to run to your corners.

Failed IVF- a serious nuisance. But even before entering into the protocol, the couple must make every effort so that the “flight” does not turn into a tragedy of a lifetime.

Unsuccessful IVF is not a death sentence, but an opportunity to better understand yourself

Most women who are unable to get pregnant on their own decide to undergo IVF in anticipation of a cherished miracle. But what to do if a miracle does not happen, and each subsequent attempt leaves less and less less hope for a positive result?

How does a woman feel after unsuccessful IVF?

Usually, emotional condition in a woman after unsuccessful IVF quite unstable and difficult to predict. The first feeling that arises is guilt about one’s own failure as a woman or about the fact that it was not possible to live up to the expectations of one’s husband or relatives. Self-flagellation can continue for a very long time and eventually develop into more severe form such as neurosis, apathy or depression. In this case, it is almost impossible to get out of this state without the help of a specialist.

In addition, the woman begins to experience fear and doubts before the next IVF protocols. She begins to fear that a future attempt will again be unsuccessful. Sometimes a condition arises when a woman leaves negative thoughts. She tries to keep herself busy, distract herself, and simply not think about it. This means that one of the mechanisms has started working psychological protection, but this is not always effective, since the experiences still do not go anywhere, but are only temporarily removed from the conscious aspect.

A woman may also experience unexplained irritability, restlessness, and anxiety. Sometimes after unsuccessful IVF a woman often begins to seclude herself and artificially isolate herself from any contact with the outside world.

Reaction of husband and loved ones after unsuccessful IVF attempt

It is no less difficult for the husband, because it is also difficult for him to come to terms with the fact that he will not have the heir that he and his wife have dreamed of for so long. A man can also experience a variety of experiences about this. And relatives who were expecting good news are faced with a harsh sentence. Their hopes and plans are destroyed. But no matter how difficult it is for relatives and husband, their experiences cannot be compared with what the woman herself feels.

The most correct thing in such a situation would be to provide her with moral support. We need to show the woman that she is not alone with her problem, that she is still loved and accepted. She must feel that failed IVF procedure did not in any way affect the attitude towards her on the part of her relatives and her husband. In order not to further traumatize a woman, you should not often try to talk to her about such a topic, unless she herself does not want to.

Psychological reasons for IVF failures

Of course, the role of physiology in this matter is very important, but there are also many reasons and factors of a different nature that can significantly influence the result of the IVF procedure. So, let's focus on the most basic reasons for unsuccessful IVF:

1. Unpreparedness to be a mother, inability to imagine oneself in this role.
2. Distrust of the doctor, doubt in his competence.
3. Perception of the IVF procedure as something unnatural and dangerous.
4. Conviction in advance of a negative outcome.

Thus, most often, a woman already knowingly, going through the IVF procedure, gives herself a negative attitude, and thereby subconsciously sets herself up for a bad outcome of events. It has long been proven that our thoughts tend to materialize, so they are easily reflected in the outside world. If a woman is not yet psychologically ready for motherhood, then the body naturally rejects the implanted embryo as something foreign and unnecessary. Therefore, it is better to wait until the moment when a woman feels the strength to take responsibility for her own child.

Unsuccessful IVF – what to do? How to help yourself?

We cannot change what nature has laid in us, but we can change our thoughts and actions, and therefore significantly influence the course of events. The first thing to remember is that you should not blame yourself or others for what happened. If you have already had several unsuccessful attempts to get pregnant using IVF, this does not mean that your chances are exhausted. Let's not forget that it is very rare for women to get pregnant the first time, even naturally. Sometimes this takes entire months. Therefore, there is always an opportunity for success!

Second, no less important aspect– learn to remove your negative feelings about this issue. There are several very effective techniques for this. For example, you can write down all your accumulated negative emotions on a piece of paper. Don't think, just write down everything that comes to your mind. When you finish, you will feel noticeable relief. For greater effect, you can tear or crumple the paper and throw it in the trash.

Music therapy is another effective way improve your condition. Choose an invigorating, cheerful melody, and continue with your business as usual. You can dance a little if you want, and you won’t even notice how quickly your mood will improve and your depression will disappear. An aromatherapy session that you can arrange in your bathroom will be no less pleasant. Give preference essential oils or .

To next procedure IVF was successful, and you have finally found the happiness you have long dreamed of, try using the visualization method. Sit in a comfortable and quiet place where you will not be disturbed. With your eyes closed, first imagine that the doctor is telling you the good news about your pregnancy. How does this make you feel? Then draw in your imagination yourself with a rounded tummy, look at yourself from the outside. Finally, think about holding your baby in your arms. How does this make you feel? Try to imagine all this in maximum detail and detail, as if it had already happened. Take a deep breath and slowly open your eyes. Do this exercise as often as possible, so you can quickly convince yourself that this time everything will work out. And, of course, don’t forget about a positive attitude!

Remember, there are always chances, and you should never give up, even if it seems impossible to win!

Pregnancy is a real happiness for any family. But, unfortunately, not every woman is given the opportunity to know the joy of motherhood. If for a number of reasons pregnancy does not occur naturally, a specialist may recommend an IVF procedure. This is an artificial transfer of embryos into the uterine cavity. However, there is no guarantee at all that a long-awaited child will soon appear in the family. After unsuccessful IVF, you can try again after some time. But first you should find out why the pregnancy did not occur.

Poor quality embryos

The IVF procedure consists of implanting embryos into the uterine cavity. After unsuccessful IVF, you should definitely find out why pregnancy did not occur. The primary cause may be poor-quality embryos. Organisms consisting of 7-8 cells that demonstrate excellent division rates are considered ideal for replanting. If the embryo develops slowly during maturation, it is likely that nothing will change in the uterine cavity. Such a pregnancy, as a rule, freezes at an early stage, and the embryo is released during the next menstruation.

In most cases, bad embryos are formed from sperm and eggs with poor performance. Therefore, rehabilitation after unsuccessful IVF necessarily includes both partners. The man must perform a spermogram, and the woman must undergo an examination by a gynecologist. The specialist takes tests and swabs of the genital organs of the man and woman.

An experienced embryologist is able to accurately assess the condition of the organism that is implanted into the woman’s uterine cavity. This should be an embryo with maximum performance, without fragmentation. If the organism has a non-standard shape or is characterized by slow division, it is not added for further development pregnancy. Most likely, such an embryo is not destined to become a fetus. Success directly depends on the specialist who performs the procedure. Therefore, preference should be given to clinics that have proven themselves well. After unsuccessful IVF qualified specialist will try to identify the cause of the current situation and will do everything to ensure that the desired pregnancy occurs.

Endometrial problems

The structure and size of the endometrium has one of important roles during embryo transfer. As a result of numerous studies, it has been revealed that in vitro fertilization is successfully carried out when the thickness of the endometrium is 7-14 mm. Such indicators are enough for the embryo to securely attach to the uterine cavity. Before carrying out the procedure, the specialist must conduct an examination using an ultrasound machine. After unsuccessful IVF is also carried out full examination uterine cavity. Endometrial pathologies are rejected by a specialist first of all. The fact is that it is precisely the problems with this part female body most often provoke premature termination of pregnancy.

Chronic endometritis is a major pathology that can interfere with the development of a healthy pregnancy. The disease can be easily determined using echography. A vaginal sensor helps determine the presence of fluid in the uterine cavity, as well as measure the amount reproductive organ.

It is worth noting that the condition of the endometrium in a woman’s uterine cavity directly depends on local immunity. If a representative of the fairer sex has poor body resistance to pathogenic bacteria and viruses, the IVF procedure will most likely not end well. After unsuccessful IVF, a woman should definitely undergo general analysis blood. Special attention paid to the amount of hemoglobin. If this parameter is below normal, the patient is prescribed immunostimulating and iron-containing drugs.

Fallopian tube pathologies

If after unsuccessful IVF there are no periods in the second cycle, the patient should pay attention to the condition fallopian tubes. One of the most serious pathologies is the presence of hydrosalpinx. As a result of obstruction of the fallopian tubes, a woman becomes completely infertile. Even the IVF procedure does not give the desired result.

Hydrosalpinsk is a serious pathology in which fallopian tubes Excessive fluid accumulates. The most common cause of the disease is chronic inflammatory processes in the small pelvis. Less commonly, obstruction develops as a result of structural features of the uterus. In the second case, the problem is solved by surgical intervention. It is worth noting that hydrosalpinxes occur both solitary and follicular. In the first case, it is possible to get rid of the problem much faster. In what exact form the disease has affected the fallopian tubes can be found out only after a complete examination of the uterine cavity.

The problem is that at an early stage, hydrosalpinsk practically does not manifest itself at all. The disease can only be detected during an ultrasound. Before preparing for IVF after an unsuccessful attempt, it is worth treating the pelvic organs, as well as getting rid of obstruction of the fallopian tubes, if any. Some clinics also practice radical treatment. Tubes in which hydrosalpinx is found are completely removed. As a rule, after such an operation as a result of in vitro fertilization, women successfully become pregnant.

Genetic abnormalities

If pregnancy does not occur again after an unsuccessful IVF attempt, geneticists recommend taking a karyotype test. This is the only way to determine whether one of the partners has deviations. Wrong in most cases developing embryos do not stay long in the uterine cavity. As a result, the couple is forced to worry great amount unsuccessful attempts at in vitro fertilization.

Often, spouses who suffer from infertility experience an inversion of the ninth chromosome. Unfortunately, it is impossible to correct this pathology. All that remains is to believe in a miracle. In one out of ten cases, it is possible to get pregnant normally and give birth to a healthy baby.

For patients who have relatives with genetic disorders, it is advisable to create an individual genetic tree. In this way, the embryologist is able to identify the likelihood of a low-quality embryo developing. If the possibility of a healthy pregnancy exceeds 50%, in vitro fertilization is still performed. If found genetic abnormalities, future parents are recommended to undergo a series of tests. The examination helps determine whether future offspring will inherit abnormalities that are inherent in the karyotype of the parents.

It is worth remembering that problems with genetics are not a death sentence. Some diseases are inherited only by certain offspring. In vitro fertilization has one significant advantage. This is an opportunity to plan the gender of your future baby.

Problems with a woman's immune system

It can be quite difficult to predict the outcome of an IVF procedure. After unsuccessful IVF, many experts recommend that a woman undergo immunological study body. With the help of tests, it is possible to determine the presence of antibodies to major infections.

Genetic incompatibility is also a problem for many couples. Most often, this situation is observed in spouses with Rh-conflict, when the woman, for example, has and the man is positive. The body of the expectant mother perceives the embryo as foreign body. Antibodies are activated and kill the small organism, which has not yet had time to properly gain a foothold in the uterine cavity. To prevent such a situation from arising, a woman who has Rh negative, spends several days after fertilization in the hospital. If necessary, the expectant mother is given a small dose of the drug “Immunoglobulin”.

Patient's age

Often patients of in vitro fertilization clinics are women over 40 years of age. Representatives of the fair sex throughout for long years trying to get pregnant in a natural way and only finally apply for qualified medical care. But precious time may already be lost. The problem is that as a woman ages, her fertility declines significantly. The IVF procedure may not always go well. After unsuccessful IVF, older women need much more time to recover.

The age of the future father also matters. Often, young girls cannot get pregnant just because their sexual partner is already 45. Every year, the quality of sperm deteriorates significantly. Men with overweight and lovers of alcohol and cigarettes.

Middle-aged partners who came for the IVF procedure for the first time require increased attention from the outside medical personnel. The couple will have to undergo a full examination of the body and undergo a series of tests before transferring the embryo into the uterine cavity. It is not uncommon for women over 45 years of age to not have periods for 3 months after unsuccessful IVF. There is a possibility that the fairer sex has entered the menopause phase, and pregnancy will no longer occur for physiological reasons.

Overweight

Obesity is almost always an obstacle to normal pregnancy. Most often problems arise already at early stages. This is due to the pathology of the development of ovarian follicles. How to recover after unsuccessful IVF? First of all, you need to reset B private clinic You can use the recommendations of a nutritionist. Working out in the fitness room won't hurt either.

The problem for the birth of healthy offspring is not only female obesity, but also male obesity. Representatives of the stronger sex with overweight bodies most often have a bad spermogram. As a result, low-quality embryos mature and die in the uterine cavity after replantation.

Recovery after IVF

The female body returns to normal after an abortion in different ways. It all depends on physiological characteristics. It often happens that after unsuccessful IVF there are no periods. Reviews from doctors show that the cycle is restored within several months. If the next menstrual bleeding does not arrive on time, it is recommended to pass additional examination at the gynecologist. The specialist can prescribe hormonal drugs, which will help restore the cycle painlessly.

After unsuccessful fertilization, heavy periods may also occur. There is no reason to panic, but it is still worth consulting a doctor. Perhaps this is the way the female body gets rid of an embryo that has not taken root in the uterine cavity. The first menstrual bleeding after unsuccessful in vitro fertilization can last 7-10 days.

Pregnancy after an unsuccessful IVF procedure

According to statistics, in 30% of cases, couples after unsuccessful IVF manage to get pregnant naturally. This is due to the stimulating procedures that are carried out in the clinic. After all, specialists not only implant the embryo into the uterus, but also conduct a full examination of both partners and identify the cause of infertility. Many diseases after treatment give good result. Within three months it is possible to achieve the desired pregnancy. After unsuccessful IVF, a missed period can be a real surprise.

If in vitro fertilization was unsuccessful, you should not despair. You can try again next month. The couple needs to lead at all times healthy image life and eating right. The specialist’s task is to identify the cause of failure. It may be necessary to treat both partners in a hospital setting. Additionally, you will have to undergo a number of tests.

Let's sum it up

The in vitro fertilization procedure requires considerable financial costs. You can understand the spouses if the desired pregnancy does not occur as a result of long efforts. However, there is no need to despair. The main thing is to follow all the doctor’s recommendations and undergo a full examination of the body. In most cases, pregnancy occurs on the second or third attempt.

The IVF procedure is not harmful to the female body. Therefore, you can perform it an unlimited number of times. However, after several unsuccessful attempts, a specialist may recommend an alternative - replanting or sperm.

When conducting artificial insemination, it is not always possible to get pregnant the first time. If this does not work, a second IVF attempt is made. will be successful, with a scrupulous analysis of the previous failure and additional examination.

Reasons for failure

Despite careful preparation for the procedure, no one gives a complete guarantee of a positive outcome. The first embryo transfer is rarely successful, but the chances of a second IVF attempt increase significantly. Repeated fertilization does not harm the patient’s health and is absolutely safe.

Some parents-to-be are worried about availability possible deviations in children born after frozen embryo transfer. According to the research results, no pathologies in the child’s development were identified. The percentage of children born with any disorders using cryotransfer is no higher than that of children conceived naturally.

Deadlines

After how long can you do a repeat eco? The timing of a new attempt at artificial insemination mainly depends on the recommendations of the attending physician and the desire of the woman. By coordinating these indicators, through certain time, you can do IVF, usually it takes 2-3 months. But considering individual characteristics body, only the doctor will determine when a second IVF attempt can be made, after two months or after a longer time.

But no specialist guarantees that second IVF attempts will be successful. Therefore, it is important, after each failure, to correctly determine the reasons that prevent pregnancy. But the inability to get pregnant for the first or second time is not a reason for despair. Many factors can be eliminated, and in half of the cases the woman carries and gives birth to a healthy child.

Only in difficult situations, after three unsuccessful attempts, doctors suggest taking other options. For example, the use of donor embryos, sperm or eggs. Sometimes, only surrogacy is possible. But before making a decision, you should not refuse to make another attempt at fertilization.

Modern medicine uses the latest techniques, and now almost every woman can become a mother. Everything should be considered as a new step towards successful pregnancy. At the next transplant, they are minimized negative factors previous procedures.

It’s a shame, but half of all those who took part in the IVF procedure have a chance of successfully completing the IVF procedure the first time. This is not a reason to completely give up the chance to have children. It is important to understand that fertilization can be carried out several times. The most important thing is not to give up. Let's take a closer look at why there are unsuccessful attempts and what to do next.

Given the already small chances of developing pregnancy, these indicators are further reduced if any kind of pathology is detected.

The most common reasons failures are:

1. Poor quality of embryos. In order for the manipulation to be successful, the number of cells in the embryo should be from 6 to 8 pieces. In case of an unsuccessful attempt, which was associated precisely with poor-quality material, it makes sense to look for a more qualified embryologist or andrologist.
2. Pathological conditions of the endometrium. An endometrial thickness of 7-14 millimeters is most suitable for the IVF procedure, and the presence chronic endometritis may interfere with its successful completion. Such diseases also include: hyperplasia, small thickness, and the presence of polyps.
3. Anomalies of the fallopian tubes. If fluid is found in the tubes, then pregnancy cannot develop. This condition requires mandatory treatment.
4. Genetic failure.
5. The presence of a similar HLA antigen in both parents.
6. Detection of specific antibodies in a woman that block pregnancy.
7. Endocrine and hormonal pathologies.
8. Age.
9. Availability bad habits and excess weight.
10. Cases when a woman did not follow the instructions of the attending physician for an appointment medicines.
11. Determination of polycystic condition in the ovaries.
12. Lack of follicle reserve, which arose due to depletion, inflammatory process or surgical intervention.
13. The presence of concomitant chronic and infectious diseases different organs and systems.
14. The appearance of conditions in a woman during IVF that require immediate intervention.
15. Adhesions in the pelvis.
16. Detection of external genital endometriosis.
17. The presence of congenital and acquired anomalies.

Restoration of menstruation

After an unsuccessful IVF attempt, doctors devote all their efforts to the woman’s recovery menstrual cycle.

No one can predict the body's reaction to in vitro fertilization. In most cases, periods come on time, and the delay does not cause any confusion - this is normal condition after the procedure.

Delayed menstruation can occur due to body characteristics or health conditions.

It is also possible for heavy periods to occur, which does not indicate serious pathologies and does not require correction. There is information about the gain pain during this period, lengthening of the period or the appearance of clots. It is the previous IVF attempt that explains these anomalies.

Don't panic. The next cycle will be fine. In case of deviations, you must see the doctor who performed the manipulations. It is important to remember that a delay in menstruation does not in any way affect the chances of pregnancy in subsequent IVF attempts.

Pregnancy after

Statistics say that a quarter of all patients who have had an unsuccessful IVF attempt experience a natural pregnancy. Doctors explain this by the activation of the hormone cycle, which is triggered by the technique used in artificial insemination.

What to do after failure

To achieve the goal, women are ready, after an unsuccessful attempt, to change not only the clinic, but also the country.

In some cases, this can give results, because an experienced doctor is half the success. Practice shows that to achieve success you must adhere to the following rules:

1. You need to rest between protocols. To do this, you don’t just need to lie on the couch, but study special exercises, which will improve blood flow in the pelvis.
2. If you wish, you can return to sexual activity not according to a schedule, but at will.
3. Additional examination is carried out and tests are taken. This will help minimize risks in future attempts.
4. It is allowed to use mud treatment, massage, leeches. Before deciding to use any method, you should consult your doctor.
5. It is important not to cultivate depression in yourself, psychological attitude- one of important factors to achieve success. If a woman is under stress, the chances of favorable outcome procedures are significantly reduced. Very often, women cannot control themselves and turn to a psychologist for help.

How to prepare (video)

Doctor's actions

After an unsuccessful attempt at fertilization, the attending physician must pay attention to the following factors:

• the quality of the obtained embryos and the condition of the endometrium;
• how ready a woman’s body is for IVF;
• ovarian response to stimulation;
• pathological conditions of the uterine wall during the procedure;
• Is it necessary to further examine the woman and apply treatment before the next attempt;
• the need to change the doses of medications responsible for the superovulation process;
• Is there a need to use a donor egg?

When they repeat

The instructions for in vitro fertilization describe that a second attempt can be made as early as next month if the woman’s wishes, her state of health and the doctor’s recommendations completely coincide.

In most cases, the break is from 2 to 3 months. This is necessary in order to restore strength, get rid of stress, and regulate the functioning of all organs.

Necessary tests

After an unsuccessful in vitro fertilization procedure, a woman is required to take tests and undergo additional examinations.

If hidden inflammatory processes in the uterus are detected, the patient will have to undergo treatment, which consists of using:

• medicines;
• physiotherapeutic activities;
• laser therapy;
• methods of alternative medicine.

Number of attempts

Doctors believe that the in vitro fertilization procedure has no significant negative impact on the woman's body. No doctor can say with accuracy how many procedures will be needed until the goal is achieved.

There is information about 8 or even 9 attempts. In most cases, after the third or For the fourth procedure, doctors suggest that the couple turn to alternative methods: the use of donor germ cells or surrogacy.