What can replace chimes for pregnant women? Visitor survey results

Curantil is a drug that is dispensed from pharmacies only with a doctor’s prescription, its cheap Russian and foreign analogues, for the most part, too.

This article is not intended for you to replace your doctor’s prescription; it is for informational purposes only and compares prices for Curantil and its synonyms and analogues, drugs with similar effects!

Only a doctor can replace a drug, especially one as serious as Curantil, who will select an analogue not only taking into account the patient’s economic capabilities, but also after carefully studying the medical history. It is important to remember that even the same composition does not guarantee that the analogs will be suitable for the patient.

Curantil: cheap analogues

In principle, Curantil has only one analogue, or rather, even a synonym, that is, a drug that absolutely and completely corresponds to Curantil itself in all respects. This is Dipyridamole. Dipyridamole is produced by domestic manufacturers in dosages of 25 and 75 mg per tablet. Let's try to figure out why doctors prescribe this remedy and how analogues differ from the original.

Curantyl and Dipyridamole: twin brothers

Although active component Both drugs contain dipyridamole at a dosage of 25 or 75 mg, patients, especially those prone to allergies, should be aware that auxiliary components However, they may differ slightly depending on the manufacturer. Therefore, in the presence of individual reactions hypersensitivity Replacing Curantyl with an analogue may not be suitable for such a patient.

Of course, Curantil will cost much more than its analogues Russian production. If Dipyridamole 25 mg in a package containing 100 tablets costs about 370 rubles ($6), then a similar package of Kurantil costs 580 rubles ($7.5).

The doctor may also recommend other medications for replacement. They are not synonyms of Curantil and are not analogues, however, they can be used in the treatment of the same diseases as Curantil due to their antiplatelet (antithrombotic) effect. Let's try to dwell on them in more detail.

There are many drugs with similar effects, ranging from the well-known pentoxifylline and xanthinol nicotinate to new drugs such as clopidogrel, but all of them are available by prescription and
We will not focus on them.

Among over-the-counter products, an analogue of chimes is aspirin and its derivatives and several herbal preparations.

Acetylsalicylic acid or the respected Aspirin

Yes, yes, aspirin can not only lower the temperature and eliminate headache, but also reduce blood viscosity. That is why it, like other analogues, can replace Curantil under such medical instructions. Regular use of Aspirin in reduced doses is used to thin the blood. By the way, most patients do not know that Aspirin has a wide range of contraindications and an even more extensive list side symptoms. Without medical advice frequent use can seriously undermine health, up to fatal outcome. For comparison, Curantil is much better tolerated than acetylsalicylic acid and does not have such harmful effects on the mucous membranes of the gastrointestinal tract. The price of the drug is a pittance. For 10 tablets
you will have to pay 6 rubles.

ATTENTION! Even the legendary and over-the-counter aspirin sometimes has fatal complications, especially in children (Reye's syndrome)!

Ginkgo biloba

Ginkgo Biloba– a herbal over-the-counter drug according to the classification is classified as a group of chimes analogues.

Ginkgo Biloba is a plant with anti-aggregation properties; it is part of many combined food additives, and is also used as independent drug. In Russian pharmaceutical market very popular, but not approved as a medicine in the USA.

Preparations based on Ginkgo Biloba have a very wide range of prices, from 120 rubles ($2) to 1600 rubles ($25), it depends on the manufacturer and the number of tablets in the package.

It has no side effects as such, except for an allergy to the plant itself.

Fish fat

Also in the Russian Pharmacopoeia, in the group of analogues of chimes, there is Eikonol– sold as
edible oil or in capsules, active principle – Omega 3 triglycerides obtained from fish oil. Omega-3 triglycerides have a wide range of prices. If omega 3 triglycerides are purchased in the form of fish oil, it can be very inexpensive and sold as an edible oil. Unlike Ginkgo Biloba, fish oil is registered in the United States as a medicine for the treatment of heart disease.

Attention! Fish oil has contraindications!

Is it possible to replace chimes with fish oil?

Such a formulation of the question is possible only in the office of your attending physician, who bears full responsibility for the result. Both Curantil and its analogues, cheap or not, are often used in the treatment of serious illnesses when the patient's condition approaches critical.

Regardless of your knowledge, the drug Curantil and its main synonyms and analogue drugs require a doctor's prescription. Please consult your doctor for more detailed information.

In this article you can read the instructions for use of the drug Chime. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Curantil in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Curantil, if available structural analogues. Use for the treatment of circulatory disorders and the prevention of thrombosis in adults, children, as well as during pregnancy and lactation. Composition and contraindications of the drug.

Chime- vasodilator with myotropic action. It has an inhibitory effect on platelet aggregation and improves microcirculation.

Dipyridamole (the active ingredient of the drug Curantil) dilates arterioles in the system coronary blood flow, upon admission to high doses- and in other parts of the circulatory system. However, unlike organic nitrates and calcium antagonists, dilation of larger coronary vessels does not occur.

The vasodilating effect of dipyridamole is due to two various mechanisms inhibition: suppression of adenosine uptake and inhibition of phosphodiesterase.

In vivo, adenosine is found at concentrations of approximately 0.15-0.20 µM. This level is maintained due to the dynamic balance between ejection and reuptake. Dipyridamole inhibits the uptake of adenosine by endothelial cells, erythrocytes and platelets. After the administration of Curantil, an increase in the concentration of adenosine in the blood and an increase in adenosine-induced vasodilation are detected. At higher doses, platelet aggregation caused by adenosine is inhibited, and the tendency to thrombus formation decreases.

The breakdown of cAMP and cGMP, which suppress platelet aggregation, occurs in platelets under the action of corresponding phosphodiesterases. IN high concentrations Dipyridamole inhibits both phosphodiesterases; at therapeutic concentrations in the blood, only cGMP phosphodiesterase. As a result of stimulation of the corresponding cyclases, the power of cAMP synthesis increases.

As a pyrimidine derivative, dipyridamole is an interferon inducer and has a modulating effect on functional activity interferon system, increases the reduced production of interferon alpha and gamma by blood leukocytes. The drug increases nonspecific resistance to viral infections.

Compound

Dipyridamole + excipients.

Pharmacokinetics

Dipyridamole is almost completely bound to plasma proteins. Dipyridamole accumulates in the heart and red blood cells. Dipyridamole is metabolized in the liver by binding to glucuronic acid. It is excreted in bile as a monoglucuronide.

Indications

treatment and prevention of disorders cerebral circulation ischemic type;
encephalopathy;
primary and secondary prevention IHD, especially with intolerance to acetylsalicylic acid;
prevention of arterial and venous thrombosis and treatment of their complications;
prevention of thromboembolism after heart valve replacement surgery;
prevention of placental insufficiency during complicated pregnancy;
when planning pregnancy;
microcirculation disorders of any type (as part of complex therapy);
prevention and treatment of influenza, ARVI (as an interferon inducer and immunomodulator) - for taking the drug in a dose of 25 mg.

Release forms

Film-coated tablets 25 mg.

Film-coated tablets N 25 (25 mg).

Film-coated tablets N 75 (75 mg).

Instructions for use and dosage

The dose of the drug is selected depending on the severity of the disease and individual reaction patient.

For the prevention and treatment of cerebrovascular accidents, as well as for prophylaxis, 75 mg is prescribed 3-6 times a day. Maximum daily dose is 450 mg.

To reduce platelet aggregation, Curantil is prescribed at a dose of 75-225 mg per day in several doses. In severe cases, the dose can be increased to 600 mg per day.

For the prevention of influenza and ARVI, especially during epidemics, Curantil N25 and Curantil 25 are prescribed 50 mg (2 tablets or 2 dragees) per day in 1 dose. The drug is taken once a week for 4-5 weeks.

To prevent relapses of acute respiratory viral infections in patients with frequent respiratory infections viral infections patients Curantil N25 and Curantil 25 are prescribed 100 mg per day (2 tablets or tablets 2 times a day with an interval of 2 hours between doses). The drug is taken once a week for 8-10 weeks.

The tablets should be taken on an empty stomach, without breaking or biting, with a small amount of liquid. The duration of the course of treatment is determined by the doctor.

Side effect

heartbeat;
tachycardia (especially with simultaneous use other vasodilators);
bradycardia;
flushes of blood to the face;
facial skin hyperemia;
syndrome coronary steal(when using the drug at a dose of more than 225 mg per day);
decrease in blood pressure;
nausea, vomiting;
diarrhea;
pain in the epigastric region;
thrombocytopenia, changes in the functional properties of platelets;
bleeding;
increased bleeding during or after surgery;
dizziness;
noise in the head;
headache;
skin rash;
hives;
weakness;
feeling of ear fullness;
myalgia;
rhinitis.

Contraindications

acute myocardial infarction;
unstable angina;
widespread stenotic atherosclerosis of the coronary arteries;
subaortic aortic stenosis;
heart failure in the stage of decompensation;
arterial hypotension;
collapse;
severe arterial hypertension;
severe heart rhythm disturbances;
chronic obstructive pulmonary diseases;
chronic renal failure;
liver failure;
hemorrhagic diathesis;
diseases with increased risk development of bleeding (incl. peptic ulcer stomach and duodenum);
hypersensitivity to the components of the drug.

Use during pregnancy and breastfeeding

The drug can be used during pregnancy according to indications.

The use of the drug during lactation is possible only if the expected benefit of treatment outweighs the possible risk.

Use in children

special instructions

At simultaneous use tea or coffee (contain xanthine derivatives), the vasodilatory effect of Curantil may decrease.

Impact on the ability to drive vehicles and operate machinery

Caution should be exercised when driving vehicles and operating machinery, since as a result of a drop in blood pressure while taking Curantil, the ability to concentrate and speed of psychomotor reactions may deteriorate.

Drug interactions

When using Curantil simultaneously with anticoagulants or acetylsalicylic acid the antithrombotic effect of the latter increases and, accordingly, the risk of developing hemorrhagic complications.

With simultaneous use, Curantil enhances the effect of antihypertensive drugs.

At joint use Curantil may weaken the anticholinergic effects of cholinesterase inhibitors.

When used simultaneously, xanthine derivatives weaken the vasodilator effect of Curantil.

Analogues of the drug Curantil

Structural analogues according to active substance.

During pregnancy, every woman should be careful when taking medications. In the next article we will look in detail at why doctors prescribe chimes during pregnancy.

Chimes during pregnancy

Pregnancy is a celebration of life, a sea of unforgettable sensations and great joy for parents who are looking forward to the birth of a child. Responsibility for a small life falls on a woman from the moment of conception and continues not only throughout pregnancy, but throughout her life. Therefore, it is very important to monitor your health, change familiar image life, eat well, and of course, visit a gynecologist who will monitor the growth, development of the fetus and the pregnancy itself.

Considering the modern pace of life, poor ecology, and inadequate quality of food, many pregnant women face a number of problems that can negatively affect the health of the fetus or the woman herself. Unfortunately, with the development of disorders in the body of a pregnant woman, without drug treatment difficult to get by. Drug correction of pregnancy pathologies and their preventive actions are gaining more and more momentum, and no one is surprised that outwardly healthy woman swallows various tablets to maintain the long-awaited pregnancy.

One of the frequently prescribed drugs during pregnancy is “Curantil”, which helps improve blood flow to the placenta, reduce the risk of developing fetal hypoxia, and prevent dystrophic changes in the placenta, which can lead to premature birth or fetal death.

Expectant mothers do not always agree to take pills, as many believe that any medications during pregnancy are harmful. However, many obstetricians and gynecologists strongly recommend taking Curantil. What kind of drug is this, how does it work, does it have contraindications and should it be used during pregnancy? We will try to answer these questions, but it is worth noting that only a doctor can prescribe Curantil, and before use you should also read the instructions for the drug.

Often expectant mothers refuse to take prescribed medications

What effect does Curantil have?

"Courantil" - medicinal product from the group of antiplatelet agents and immunomodulators, which improves blood microcirculation, supplying the body cells with necessary and healthy products life activity. The active ingredient of the drug is considered to be dipyridamole, which has a vasodilator myotropic effect, improves immunity, prevents the formation of blood clots, stimulates the formation of interferon, and protects the pregnant woman’s body from the invasion of pathogenic viruses.

The formation of blood clots is observed during multicellular adhesion of aggregation cells, which provoke blockage of blood vessels, blocking blood access to individual bodies, including to the placenta. In pregnant women vascular disorders, requiring the use of "Curantil" may develop due to a violation metabolic processes, hormonal imbalance, high cholesterol in blood, concomitant diseases cordially - vascular system, and other pathologies or anomalies of the body.

"Curantil" during pregnancy allows you to relax the walls blood vessels, eliminate blockages, improve blood circulation to the placenta, as a result of which the fetus will receive sufficient quantity oxygen and nutrients, for full growth and development. Taking this medication helps prevent the development of severe toxicosis (preeclampsia) in the second trimester of pregnancy and increase the mother's body's resistance to viral infections.

In addition, taking Curantil by pregnant women improves blood circulation not only in the placenta, but also in the uterus, kidneys and other organs and systems. The main immunomodulatory mechanism of Curantil is that it promotes the production of interferon (blood protein), which has an antiviral and antitumor effect. The activity of interferon production increases immunity, which is extremely necessary during pregnancy, since viral diseases capable of causing severe complications disrupting the condition of the mother and fetus.

Chimes during pregnancy: indications

During pregnancy, everything internal organs women work harder and need nutrition and oxygen. High aggregation of blood cells in the body of a pregnant woman can lead to serious complications which have a negative effect on the body expectant mother and fruit.

Complete or partial blockage of placental vessels leads to fetal hypoxia (lack of oxygen), gestosis (long-term toxicosis), vascular spasms, edema and others. severe disorders. "Curantil" is prescribed to pregnant women for treatment and prevention the following diseases or violations:

Cerebrovascular accident, encephalopathy;

Impaired placental circulation;

Prevention of hypoxia and retention intrauterine development fetus;

Varicose veins, thrombophlebitis, thrombosis;

Microcirculation disturbance small vessels in complex therapy with other drugs;

Premature aging of the placenta;

Placental insufficiency, gestosis, fetal malnutrition;

Vasospasm, convulsions;

Prevention and treatment of viral infections;

Hypercoagulation ( increased coagulability blood);

Pathologies of the cardiovascular system: angina pectoris, heart failure, arterial hypotension or hypertension;

Kidney failure;

Decreased immunity.

Chimes will ensure the supply of oxygen to the fetus

In addition, “Curantil” will protect a woman from swelling of the extremities, headaches, and normalize the functioning of the heart. Also this drug increases the production and activity of interferon, which improves immunity and protects a woman from viral and infectious diseases. The advantage of the drug is the fact that it has a positive effect only on the placenta and does not affect the fetus in any way. After taking the drug, it does not stay in the body, is broken down in the liver and excreted in the bile.

Contraindications, side effects of Curantil

Like any other drug, Curantil has a number of contraindications:

hypersensitivity to the composition of the drug;

diseases with the development of bleeding;

hemorrhagic diathesis;

severe arrhythmias;

tonic atherosclerosis of the coronary arteries;

arterial hypotension and other heart and vascular diseases.

Usually "Curantil" is well tolerated, only in in rare cases Nausea, vomiting, dizziness may occur, general weakness body and other symptoms:

redness of the facial skin;

tachycardia and bradycardia.

abdominal pain, diarrhea, vomiting, nausea;

noise in the head, headache;

allergic reactions: itching, urticaria, rash;

increased weakness, drowsiness.

In cases of drug overdose, symptoms side effects intensify, in such cases you need to urgently rinse your stomach and seek medical help.

For how long is Curantil prescribed?

"Curantil" is prescribed for different dates pregnancy. In some cases this remedy used by a woman for 9 months, with short short breaks. In addition, many obstetricians and gynecologists recommend using the drug at the stage of planning conception. At premature aging placenta "Curantil" is prescribed in last months pregnancy.

“Curantil” does not have a harmful effect on the fetus, but only improves the condition of the expectant mother and baby, increases resistance to infections, which are certainly not needed during pregnancy, improves blood supply and nourishes the body’s cells with useful and nutritious substances.

What can replace "Curantil" during pregnancy?

If doubts arise about “Curantil”, or a woman experiences side effects, the doctor may prescribe another drug - an analogue. There are several analogues of "Curantil", they all have the same mechanism of action, composition, indications, but are produced using different technologies from different pharmaceutical companies.

Analogues of "Curantil" include: "Dipyridamole", "Parsedil", "Persantine" and others, which are produced domestically or foreign manufacturers. You can use analogues of the drug only after consultation with your doctor.

During pregnancy, it is worth following all the recommendations of a gynecologist or obstetrician, on whom the health of the unborn child often depends. Don't forget about in the right way life, proper nutrition and others important factors which will only provide positive impact on the child and the pregnancy itself.

Curantil is a powerful myotropic agent that dilates blood vessels and ensures active blood circulation, and therefore the medication is used for cerebral circulatory disorders, thrombosis, etc. The drug also promotes the production of interferon, therefore it is used as an immunomodulator in the prevention of diseases viral nature– influenza and ARVI.

Features of the drug Curantil

The main active ingredient of the drug is dipyridamole. From the content of the drug Curantil active substance in quantities of 25, 50, 75 or 100 mg medicine called:

Curantil 25;
Curantil 50;
Curantil 75;
Chimes 100.

Its purpose depends on the dosage of dipyridamole in the drug. So, for the purpose of preventing and treating cerebral circulation, as well as reducing platelet aggregation, Curantil 75 is usually prescribed; during epidemics of influenza and ARVI, Curantil 25 is indicated.

What can replace Curantil?

The drug Curantil has analogues for the active substance. Most known analogues Curantil tablets are drugs produced by different pharmaceutical companies:

Agrenox;
Dipyridamole;
Persantine;
Parsedyl;
Sanomil-Sanovel;
Trombonil.

There are no structural differences between the drugs, but the difference lies in the form of release and cost. It should be borne in mind that the higher the dosage of the active substance in the medicine, the higher its cost. So a package of Curantil 25 of 120 tablets costs 4.5 USD, while the cost of Curantil 75 produced by Berlin-Chemie (Germany) is retail sales is 12-16 USD

Persantine

An analogue of the drug Curantil 75 is injection solution Persantine. This medicine is administered intravenously and quickly enters the bloodstream, and therefore Persantine is used as a vasodilating drug (expanding the lumen of the coronary vessels) for obliterating arterial diseases limbs and as a therapeutic (preventive) agent for thrombosis, thromboembolism. The cost of the medicine is approximately 4.5 USD.

Trombonil

Another generic, Trombonil, is available in the form of coated tablets, dragees and injection solution. Trombonyl expands coronary vessels, helping to increase blood flow speed, and reduces platelet adhesiveness, preventing the formation of blood clots. Experts note particular effectiveness pharmaceutical drug Trombonil for progressive atherosclerosis.

Agrenox

For treatment and prevention ischemic stroke Doctors recommend taking an analogue of Curantil - Agrenox. According to the conducted medical research, the drug reduces the risk of stroke by 37%. Agrenox is sold in pharmacies in capsule form. Solid gelatin capsules packaged in tubes of 30 and 60 pieces. Agrenox costs an average of 20 USD.

Dipyridamole

For the purpose of prevention viral diseases The most commonly used analogue of Curantil 25 is the drug Dipyridamole. The medication, by acting on interferons, strengthens the immune system, and, accordingly, the body better resists influenza and ARVI. Dipyridamole is available in the form of tablets and suspension for oral administration. As prophylactic It is recommended to take 6 teaspoons (300 mg) of suspension per day. The cost of Dipyridamole is less than 2 USD.

Curantil and its analogues are quite popular in therapy, thanks to high efficiency impact. It is also valuable that when taking these drugs side effects observed relatively rarely, they can also be used during pregnancy with placental insufficiency, if healing effect exceeds the potential risk to the fetus.