For what diseases is nicotinic acid prescribed? What is nicotinic acid used for? How is nicotinic acid useful for the body? Drugs, indications for use, reviews

A nicotinic acid(many associate it with cigarettes, nicotine, and something very harmful), in fact, it is very useful. Moreover, this name hides vitamin B3 or niacin, also known as nicotinamide or PP. Regarding the latter, experts explain the name as deciphering a certain code - warning of pellagra.

After all, vitamin B3 is responsible for the health of the skin (about vitamins for psoriasis), although beneficial features nicotinic acid extend to metabolic processes occurring in the body.

Niacin takes part in the redox processes occurring in your body, has a vasodilating property, takes part in tissue respiration, protein and carbohydrate metabolism, and helps improve excretion. gastric juice. Vitamin B3 is also indispensable for healthy nervous system.

For the latter, he plays the role of an invisible guard who is responsible for ensuring that you always control yourself and do not lose composure in any, even the most critical, situation.

Nicotinic acid helps prevent the occurrence of pellagra, a disease rough skin. Without it, the processes of synthesis of genetic material and protein metabolism do not take place.

Today, vitamin B3 is also one of the most effective means when it comes to normalizing cholesterol in the blood, improving the functioning of the cardiovascular system and increasing blood circulation, reducing blood pressure and prevention of cardiovascular diseases.

Action of nicotinic acid

using the drug according to the instructions normalizes metabolic processes and well restores the structure of neuron fibers;
preparations based on vitamin PP improve blood circulation in the cerebral cortex and the whole body;
dilates blood vessels, thereby improving oxygen metabolism in the body;
improves human immunity;
helps remove toxins from the body.

Medicinal properties of nicotinic acid, indications for use

The drug Acidum nicotinicum, despite the fact that it belongs to the group of vitamins, should be used only as prescribed by a doctor. Nicotinic acid is often used in for cosmetic purposes for hair, skin and the whole body. It can also improve vision and memory.

The main indications for the use of nicotinic acid are:

impaired vision;
occupational intoxication, alcohol and food;
deterioration cerebral circulation, and blood supply to the extremities;
ischemic stroke;
noise in ears;
manifestations of osteochondrosis;
any form of hemorrhoids;
disturbances in liver function;
impaired metabolism, especially lipid metabolism;
pellagra (niacin deficiency);
diabetes;
increased acidity of gastric juice;
migraine.

What distinguishes vitamin B3 from many drugs is its ability to supply the blood with oxygen and promote skin rejuvenation.

An adult needs 15-27 mg of nicotine per day for men, 13-20 mg for women. If necessary, it can be increased to 3-5 g per day, but only as prescribed by a specialist.

Children aged 6-12 months need nicotinic acid in the amount of 6 mg per day. From 1-1.5 years - 9 mg per day. From 2 years to 4 – 12 mg. From 5 to 6 years -15 mg. From 7 to 10 years - 17 mg. From 11 to 13 years – 19 mg. From 14 to 17 years - 21 mg of the drug.

Among the products that contain vitamin PP, the leading position is occupied by beef liver, then quail meat, Pine nuts and black tea. Next comes tuna, nutmeg, turkey, chicken and rabbit meat. Duck meat also contains nicotinic acid, but in an amount half as much as previous meat products.

Wheat porridge, mushrooms (champignons) and dry thyme contain nicotine in small quantities.

To compensate for the lack of this compound, nutritionists advise eating buckwheat, fish, peas, dairy products, walnuts, eggs.

When heated above 100 degrees, the niacin content in products is reduced by 10-40%, depending on the time of heat treatment.

Symptoms of nicotinic acid deficiency and overdose

Symptoms of a deficiency of the substance can be very different, starting with the appearance of spots on the face (similar to sunburn), ending with vesicles and blisters on the body, which can later leave scars on the skin. There may also be damage to the mucous membranes, including the tongue and gums. Possible manifestation general weakness and lethargy.

Rashes of a dark red color often appear on the skin, the skin becomes dry and rough. Frequent urge to the toilet (diarrhea about 10 times a day). Appetite weakens and body weight decreases.

Sometimes there is insomnia and decreased attention. Often, with a lack of nicotinic acid in the body, a person’s thinking slows down and memory deteriorates.

Symptoms indicating a deficiency of nicotinic acid become more pronounced in the warm season, namely in spring and summer.

With an overdose of nicotinic acid, you may feel acute pain in the stomach, dizziness and nausea, clouding of consciousness and even fainting. Sometimes vision and hearing impairment occurs.

Such symptoms are usually observed when taking nicotinic acid 500 mg or more at a time. pure form. In case of an overdose of nicotine, you should contact ambulance. And before her arrival, open the windows to ensure the supply fresh air into the room. Give the victim water or milk to drink.

Nicotinic acid is produced in tablets and ampoules.

The tablet form of the vitamin is often used for the prevention and long-term treatment of many diseases. It is prescribed twice a year to patients suffering from poor circulation And venous insufficiency, with thrombophlebitis and trophic ulcers.

Taking nicotinic acid tablets is usually prescribed 1 tablet several times a day. Those with increased acidity are recommended to take tablets after meals and wash them down with milk or mineral water.

Why are nicotinic acid injections prescribed? Vitamin B3 injections are usually used by people who have increased acidity, and those suffering various shapes hemorrhoids and poor circulation.

Unlike tablets, injections do not have an irritating effect on the gastric mucosa, and are evenly distributed throughout the body in the shortest possible time.

They drive liquid dosage form nicotinic acid in ampoules up to two times a day subcutaneously, intramuscularly or intravenously. The drug is recommended for use in autumn and winter.

Contraindications to the use of nicotinic acid

stomach ulcer;
allergy to the components of the drug;
Nicotine should not be administered intravenously if a person is prone to surges in blood pressure;
gout, excess normal level uric acid in blood;
atherosclerosis;
cirrhosis of the liver;
pregnancy and breastfeeding;
severe glaucoma;
for bleeding of any location.

It is necessary to keep in mind the side effects of nicotinic acid:

decreased blood pressure;
temporary redness of the face or upper body;
quickly passing sensation of heat;
if you have stomach problems, the situation worsens;
Sometimes short-term dizziness occurs.

Adding cottage cheese to the diet alleviates the side effects.

How to take niacin

Unless otherwise stated directly by your doctor, take niacin tablets three times a day after meals (50 mg). Maximum single dose 2 tablets (100 mg), daily - 300 mg. Monthly course.

The injection drug is prescribed in a course of 10-14 procedures 1 or 2 times a day. I usually repeat it twice a year if there are indications (treatment of osteochondrosis, for example).

With rapid intravenous administration, the sensations are similar to those that occur during injection calcium chloride- fever, redness of the face, upper shoulders, chest. The sensation lasts for about 10-15 minutes.

Therefore, the drug should be administered slowly and after meals.

Electrophoresis is a therapy in which drugs are administered through the skin using low-intensity electrical impulses.

Indications for the use of electrophoresis include: diseases of the spine and joints, respiratory tract, gastrointestinal diseases, genitourinary system, in case of violation in motor functions body, as well as diseases in the field of dentistry. Quite a few drugs can be administered through the skin using electrophoresis. Nicotinic acid is no exception.

The most popular recipe using nicotine is the Ratner recipe, in which the vitamin PP preparation is used in combination with aminophylline. This mixture is prescribed for treatment inflammatory processes in organism. Regular electrophoresis courses - 10 procedures.

One of the main advantages of this method is full activation active ingredients, and their introduction in ionized form. Also, current pulses increase the immune response to external irritants. Electrophoresis with vitamin PP promotes the accumulation of the substance in cells, therefore, the effect lasts for a long time.

Nicotinic acid for facial skin care

Nicotinic acid for the face is used in cosmetology to improve skin condition, treat acne and prevent early aging. The product contains substances necessary to maintain not only beauty, but also the health of the body.

Useful properties of the drug

Nicotinic acid for the face is a complex of vitamins B and PP. They are playing important role in metabolic processes and affect the condition of the skin and hair. These substances are found in food, but most often in daily diet their food is not enough. Nicotinic acid has nothing to do with the toxic nicotine from tobacco products.

After the age of 20, the need for vitamins PP and group B increases significantly. If up to 12-14 years of age it is enough to consume 10-13 mg per day, then by the age of 20 this figure reaches 20 mg per day. Therefore, by the age of 30, a constant lack of these microelements begins to manifest itself in appearance.

IN for cosmetic purposes use tablets and ampoules with active substance. They are used internally and externally. The main beneficial properties of the drug:

improves blood microcirculation, promoting the active supply of nutrients to skin cells;
helps eliminate inflammatory processes;
affects skin color, improving it, removes pigmentation;
removes from the body excess liquid, relieves swelling of the face;
protects against aggressive sun rays;
participates in redox processes;
promotes the production of a number of enzymes that affect the condition of the dermis;
participates in the synthesis of hormones necessary for skin health;
normalizes work sebaceous glands, eliminating acne;
prevents the development of tumor tumors;
restores elasticity and firmness to sagging facial skin, smoothes out fine expression wrinkles.

Substances that are the basis of nicotinic acid are also found in medicinal plants. There are many of them in sage, rose hips, ginseng, burdock root, hops and other natural “healers”. The combination of plant raw materials and concentrated preparation enhances the therapeutic and cosmetic effect.

Nicotinic acid for facial skin is used as an additive to various cosmetic products. It is added to masks, serums, lotions. When taking a vitamin complex orally, you must strictly adhere to the recommendations of your doctor or cosmetologist. Taking pills in the usual way with water. The liquid drug in ampoules is administered into the body by injection.

On average, the course of therapy is no more than two weeks. These vitamins are often prescribed in the periods before and after plastic surgery, as they speed up the process of tissue repair and help quickly relieve inflammation of injured skin areas.

An overdose of vitamins B and PP may cause unpleasant consequences. Signs of excessive accumulation of these microelements in the body are:

skin rashes similar to allergies;
redness of some parts of the body - arms, head, neck, chest;
fainting;
numbness of fingers and toes;
dizziness;
nausea.

To the use of acid as an additional ingredient in external products special contraindications No. But, it should be treated with caution by those who suffer from allergic reactions.

Before trying a vitamin complex, it is advisable to conduct a skin sensitivity test to its components. To do this, apply it to a small area of skin on your arm and wait 20-30 minutes. If no reaction occurs, then you can safely use nicotinic acid for cosmetic purposes.

Masks with nicotinic acid

To prepare masks, it is better to use vitamins in ampoules. They can be purchased at any pharmacy at affordable price. Before applying the mask, the face is treated with a cleanser. The procedure should be carried out no more than 2 times a week.

Recipes for effective masks:

To improve skin color and condition. 2 ampoules of vitamins, 1 tablespoon of ginger juice. Mix and apply to face with a cotton swab. After 20 minutes, rinse with warm water.
Whitening. 1 tablespoon kefir, 1 teaspoon acid. Mix and apply to face, excluding mouth and eye areas. After 15 minutes, wash off.
Nutritious. 2 teaspoons of regular moisturizer, 1 ampoule of vitamins. Combine the ingredients into a homogeneous mixture and apply to the skin before bed. You don't have to wash it off.
Moisturizing. 1 teaspoon honey, 1 teaspoon grape or olive oil, 1 ampoule of nicotinic acid. Combine honey with oil and heat in a water bath until warm and liquid. Add vitamins to the mixture. Before applying, you can steam your face to nutrients penetrated deep into the epidermis through open pores. Keep the mask on for 30-40 minutes, then rinse with warm water.
Cleansing. 10 grams cosmetic clay(white or blue), 10 grams lemon juice, 1 ampoule of vitamins. Dilute citrus juice with water in a 1:1 ratio. Mix it with nicotinic acid. Add clay and mix. The consistency should be like sour cream. Apply to face for 30 minutes.
Pull-up. Take hyaluronic and nicotinic acids in equal proportions. Mix. Apply to skin using cotton pads. Rinse off after 20 minutes with cool water.
From freckles and age spots. 1 tablespoon honey, 3 tablespoons lemon juice, 5 drops acid. Mix all. Apply to facial skin twice a day for 20 minutes for 7 days.
For aging dry skin. Take 1 teaspoon each of glycerin, vitamin A, tocopherol, mineral water. Combine them in one cup and heat in a water bath. Add 1 ampoule of vitamins to the mixture. Soak a gauze cloth with the product and apply it to your face for 30 minutes. Cover your eyes with cotton pads first.
Moisturizing and toning. Boil with milk cereals. Mix 1 tablespoon of cooked porridge with 1 tablespoon of softened banana and 10 drops of nicotinic acid. Distribute everything evenly over your face. Wait until the mask dries (20-30 minutes), then rinse off.
Rejuvenating. 1 protein chicken egg, 1 teaspoon of honey, half a teaspoon of vitamins, 2 tablespoons of overripe banana pulp. Mix everything and apply to face for 15 minutes.

Nicotinic acid and acne treatment

Nicotinic acid is used in the treatment of acne, as well as during the period of skin recovery after illness. Numerous reviews indicate that the product helps. To eliminate acne and blackheads based on vitamin complex You can prepare a variety of cosmetics.

Recipes for problem skin with inflammation:

Mask for oily problem skin. Mix 1 tablespoon of calendula with 1 tablespoon of birch buds. Pour water over them and boil until a strong decoction is formed. Heat 1 teaspoon in a water bath coconut oil. Mix 3 tablespoons herbal decoction, oil and 1 ampoule of nicotinic acid. Soak a gauze or cotton napkin in the mixture and apply to the face. When dry, repeat steps until the mixture runs out.
Acne lotion. Pour 1 teaspoon each of nettle, sage and chamomile into a porcelain bowl. Brew the herbs with boiling water and leave for 30 minutes. Strain and add 2 ampoules of vitamins. Wipe your face with lotion 2 times a day. Store the product in the refrigerator for no more than 7 days. Read more:
Acne mask. Mix 1 tablespoon of aloe juice and 2 ampoules of nicotinic acid. Apply the product to the face using a cotton sponge. Wash off after 20 minutes.
Mask for enlarged pores and blackheads. 2 dessert spoons of fresh low-fat cream, 1 teaspoon of lemon juice, 2 teaspoons of fresh raspberry pulp, 1 ampoule of vitamins. Mix everything well and apply to face for 15-20 minutes.

Hello, dear blog readers. We all know about the benefits of vitamins, their role in maintaining the proper functioning of organs and systems. However, there is a single vitamin that is classified as a medicinal vitamin due to its ability to cure many diseases. In this article I will tell you about the use of nicotinic acid, also known as vitamin B3 or PP.

Application in medicine

Vitamin B3 controls the occurrence of oxidation and reduction reactions in all organs and tissues. And since they are the basis of the life activity of each cell, then, accordingly, without nicotinic acid, stable and adequate functioning of the entire organism is impossible.

A nicotinic acid

Direct indications for the use of vitamin PP are:

pellagra– a disease that occurs against the background of vitamin deficiency, which occurs due to prolonged malnutrition, lack of nicotinic acid, proteins and tryptophan. Pellagra is characterized by diarrhea, dermatitis and dementia;
diabetes. The acid activates enzymes that are responsible for the production own insulin, which allows you to reduce the dosage of the hormone coming from outside. In addition, the vitamin protects pancreatic cells from damage, thereby preventing the progression of the disease;
diseases of the heart and blood vessels. Nicotinic acid reduces levels bad cholesterol and atherogenic lipid fractions, reduces the likelihood of blood clots and dilates blood vessels. It improves blood circulation, promotes the production of energy necessary for normal functioning heart muscle, increases the chances of survival after myocardial infarction;
osteoarthritis. When treated with vitamin, the intensity decreases pain syndrome, joint mobility increases;
neuropsychiatric disorders . Thanks to sedative effect, the ability to increase brain performance and enhance the effect of other medications, the medicine is used in the treatment of depression, anxiety, decreased concentration and attention, alcoholism, schizophrenia;
poisoning with toxic substances;
migraine. Reduces the intensity and shortens the duration of attacks;
Digestive problems. The vitamin accelerates the breakdown of proteins, fats and carbohydrates, helps digest food faster, speeds up metabolism, and helps in weight loss.

In addition, nicotinic acid activates enzymes responsible for the production of estrogen, progesterone, testosterone, cortisone and thyroxine, reduces acidity in gastritis, and serves to prevent the appearance of malignant tumors.

I am not a doctor, so I will not recommend the dosage, frequency of administration and duration of nicotinic acid therapy. I'll leave this right experienced specialist. I can only say that tablets are most often used for preventive purposes, to compensate for vitamin deficiency.

The medicine is also available in ampoules. Injections are used when serious illnesses. It could be a stroke, obstruction blood vessels limbs, osteochondrosis, liver diseases, inflammation facial nerve And so on.

The drug in injection form is administered intravenously, intramuscularly or subcutaneously.

Properties of nicotinic acid

Application in cosmetology

Nicotinic acid is used externally for cosmetic purposes. Her beneficial influence on the skin of the face has been proven in numerous clinical trials.

It restores elasticity and firmness, eliminates flaking and sagging, and activates cellular respiration.

After its use, metabolic processes accelerate and expand small vessels, complexion improves, aging processes are stopped, loss of collagen and moisture is prevented.

If you have to Plastic surgery, taking vitamin PP will speed up the restoration of the skin.

The drug also relieves inflammation, acne, acne, age spots, freckles and redness. It removes bags under the eyes, protects against negative influence ultraviolet radiation, prevents the appearance of cancer cells.

Types of nicotinic acid

It is better not to use the medicine in its pure form, so I recommend that you use several simple mask recipes:

to enrich the skin with beneficial substances and normalize the level of moisture in the tissues, mix 1 ampoule of acid, 5 milliliters of olive oil and the same amount of honey. Warm it up a little. Steam your face, apply the composition to it, rinse after 40 minutes;
if you want to get rid of acne, prepare a strong decoction of a tablespoon of calendula and birch buds. Measure out 45 milliliters, add 1 ampoule of vitamin B3 and 5 milliliters of warmed coconut oil. Soak a cosmetic wipe with the nourishing cocktail and place it on your face. Leave for 30–40 minutes, periodically moistening the napkin with the prepared product;
A mixture of ampoules of hyaluronic and nicotinic acid helps well against wrinkles. It needs to be applied to the skin, left for 20 minutes, and then washed off.

The vitamin has a beneficial effect on hair, eyebrows and eyelashes. It accelerates their growth, restores damaged structure, prevents fragility, and stops hair loss.

Nicotinic acid for hair

Using simple recipes, you will also be able to increase volume and thickness, and prevent the loss of natural pigments:

combine 2 ampoules of acid, 5 milliliters of aloe extract and 5 drops of propolis tincture. Treat the root area, wrap the head in cling film, insulate it, leave for 40-60 minutes;
mix 15 drops of castor and burdock oil, add 1 ampoule of vitamin. Treat eyebrows and eyelashes, leave for half an hour;
combine 30 milliliters of liquid honey, 1 yolk and 1 ampoule of acid. Apply to scalp and curls and leave for 20 minutes.

When using nicotinic acid, remember that it must be used as quickly as possible. Otherwise, the product will lose its healing properties.

If you don't like home remedies, you can purchase niacin ointment.

Nicotinic acid: application

Contraindications

Before Use medicine, carefully read the contraindications:

individual sensitivity;
hypertension;
stomach ulcer and duodenum;
liver dysfunction;
gout;
hyperuricemia;
arterial hypertension;
children (at the discretion of the pediatrician).

During pregnancy and lactation, taking the drug is permitted only on the recommendation of a specialist.

Do not forget that the vitamin also causes side effects. It can cause redness accompanied by tingling and burning, dizziness, hypotension, urticaria, dyspepsia and increased production of gastric juice.

Long term use large doses possible diarrhea, anorexia, vomiting, liver problems, arrhythmia, hyperglycemia, decreased glucose tolerance.

Contraindications

Opinions

I suggest you read several reviews about the use of nicotinic acid:

Elena, 27 years old:

“Nicotinic acid helped me grow the eyelashes of my dreams. I mixed 1 ampoule of medicine and 2 capsules of vitamin E, applied it to the eyelashes and washed off after 20 minutes. My hair stopped falling out and noticeably increased in length.”

Svetlana, 38 years old:

“I have always tried to get rid of freckles and found, if not perfect, then quite effective remedy. You need to combine a spoon of honey, the juice of ¼ lemon and 5 drops of nicotinic acid. The composition should be applied to the skin in the morning and evening, for 20 minutes, for 7 days. Freckles really become almost invisible, and some disappear completely.”

Remember that nicotinic acid is, first of all, medicinal product. Therefore, be wise and consult a specialist before using it.

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Injections of nicotinic acid (nicotine) are prescribed for various diseases. The thing is that it affects the body differently in case of certain ailments. This drug belongs to vitamin group medicines.

Why are nicotinic acid injections prescribed and their beneficial properties?

Basically, this drug has a positive effect on the body:

normalizes the metabolic process;
restores neural structure;
leads to normal condition blood circulation in certain areas and throughout the body as a whole;
promotes vasodilation, normalization of oxygen absorption and restoration of oxidation processes inside the body;
removes toxins from the body.

Nicotinic acid injections - indications

The drug is used to treat many ailments:

stroke;
poor circulation in the head and limbs;
noise in ears;
pellagra;
poor glucose tolerance;
haemorrhoids;
obesity;
liver diseases;
blurred vision;
with medication, alcohol or occupational intoxication.

The drug is often prescribed for prophylaxis. It helps reduce the possibility of education cancerous tumors in the body and accelerates the breakdown of fats, which has a beneficial effect on their absorption in the body. In addition, it is prescribed to: remove any symptoms of hemorrhoids; treatment of gastritis; improving memory and vision.

Contraindications to the use of nicotinic acid injections

Despite the many positive properties, nicotine still has contraindications. Thus, it is not advisable for use by people who have the following ailments: atherosclerosis; stomach ulcer; problems with the duodenum; gout; hepatitis on different stages; diabetes mellitus or simply their body does not interact with the drug.

However, it should be taken with some caution by patients:

with glaucoma and arterial hypotension;
during pregnancy or during feeding.

Side effects

If nicotinic acid injections are prescribed for the treatment of bones, for example, for osteochondrosis, you need to be prepared for some side effects. For short-term use, the main ones are: skin rash and itching, unstable breathing, pain and dizziness. In addition, there is a feeling elevated temperature bodies. Basically, after some time, all symptoms go away on their own.

At long-term use nicotinic acid in injections, for example, to improve blood circulation, it is imperative to monitor other indicators of the body. The thing is that if the drug enters the body excessively, the following problems may develop:

liver dystrophy;
deterioration of glucose perception;
blood composition disorder.

At the same time, the injections themselves are considered painful.

Consequences of overdose

The dose is prescribed to each person separately, based on personal indicators of the body and age. If the amount of drug for injection is incorrectly calculated, some discomfort. So, the most common is considered to be a temporary rush of blood to the upper body and head, itching throughout the body and stomach upset. Symptoms generally go away on their own after some time, or are treated separately.

Application for weight loss

One of the most popular ailments for which injections of the drug nicotinic acid help is excess weight. Many nutritionists and personal trainers prescribe this particular medication because it helps burn fat cells. It is prescribed both in injections and tablets.

Nicotinic acid - injections for health

Vitamin PP is as important for the body as other microelements. Active influence nicotinic acid affects the body, injections of which are used to treat huge amount diseases.

Distinctive feature of nicotinic acid

It is not recommended for diabetics, as it negatively affects blood vessels. It should be taken into account that nicotinic acid is better absorbed in tablets; injections are too painful. During injections (after 10-20 minutes), redness begins to be observed, so it is recommended to lie down for a few minutes after the procedure. But even when taken orally, the dose should be increased gradually. Typically this drug is prescribed in an amount of 50-300 mg per day. It removes methyl radicals from the body, so it is taken simultaneously with methionine, vitamin U and choline chloride. And you should include more cottage cheese in your diet. The drug can be obtained at the pharmacy in the form of 50 mg tablets or ampoules of 1 ml of 1% solution.

Spectrum of action

Acid is known not only as a vitamin, it is also famous for its other properties. Thus, it is widely believed that nicotinic acid is useful for lactation. To do this, it is recommended to take the medicine 2 times a day, half an hour before feeding (1-1.5 tablets - it is advisable to find out the dosage from a specialist).

Acid for beauty

Most beauties who strive to grow gorgeous hair, sooner or later they encounter this pharmaceutical product. Many cosmetologists recommend a course of this drug, because they know that nicotinic acid for the skin is a remedy for its quick recovery. Within a couple of weeks after taking the course of the drug, the skin becomes significantly more radiant and healthy.

Side effects of niacin

Like any other drug, it cannot fail to have negative effects. They are associated with the release of histamine, and this affects the person in the following way: redness of the skin appears, accompanied by itching. Blood pressure may also decrease, dizziness, nausea and diarrhea may appear. And even if all these phenomena were caused by nicotinic acid, the injections do not yet have to be cancelled. Gradually, the body will adapt to the release of histamine and after a while will stop reacting so actively to it. But in some cases, a revision of the dosage and duration of taking the drug is required.

Contraindications for the use of nicotinic acid

First of all, nicotinic acid should be used with caution by those who experience digestive problems - it can, for example, cause an exacerbation of stomach ulcers and inflammation of the duodenum. It is prohibited to prescribe tablets to children under two years of age and parenterally at any age. People suffering from gout, liver and kidney dysfunction, as well as those who have a tendency to bleed, should take nicotinic acid with caution. If nicotinic acid is used for too long, the injections can cause appetite disturbances, vomiting, diarrhea and even liver dysfunction and exacerbation of diabetes.

"Nicotinka." Injections and tablets, their purpose and indications for use

Vitamin PP (nicotinic acid, niacin, nicotinamide) is one of the most important components human body. The lack of this vitamin leads to the appearance serious illness- pellagra, which if left untreated can lead to fatal outcome. Pellagra appears depressive state patient, sometimes - diarrhea, vomiting. Often with pellagra, the patient experiences hallucinations, accompanied by confusion of thoughts. Appearance similar signs disease should cause concern whether the cause of these symptoms is a lack of nicotinic acid? People often call this component simply “nicotine.” Injections, instructions for their use, consultation, and basic recommendations can only be given by competent employees of medical institutions.

Where is nicotine found naturally?

The main suppliers of vitamin PP (nicotine) are food. Meat, fish, milk, liver contain a lot of nicotinic acid, pectoral muscles Chicken. Plant products foods such as tomatoes, cucumbers, potatoes are also pantries that contain nicotine. injections, dietary food, tablets are prescribed by a doctor if there is insufficient or complete absence this vitamin B food products patient.

The body's needs for nicotine

Need for it vitamin preparation at different people varies depending on age and physiological state. A healthy adult who consumes a normal diet containing nicotine will most likely not need injections because daily norm Such people consume only about 20 mg of the vitamin. Boys have a higher need for nicotine than girls, and women during pregnancy, as well as during breastfeeding, should consume 25 mg of the drug daily.

Nicotine for kids

The daily intake of vitamin PP for six-month-old babies is relatively high. It should not be lower than 6 mg. It is advisable to take into account the composition of food for a child who simply needs nicotine for growth and development. Vitamin PP injections that adults receive can be harmful to children. In addition to the possibility of causing a breakdown with injections nervous activity child, there is a danger of strong burning sensation skin, which can also cause harm to a small organism.

Diagnosis

For the main symptoms of the disease, the cause of which is a lack of necotinic acid (nicotine), instructions, as well as recommendations for effective treatment can be obtained by the patient only after accurate confirmation of the diagnosis. When it is staged as main argument, the quantity, composition and even method of cooking are taken into account. By analyzing only these components, a diagnosis can be made with certainty. This is due to the good tolerance of culinary processing by vitamin PP. It is not lost when food is frozen, dried, or after exposure to high temperatures. Thus, we need extreme conditions, in which a person will completely stop receiving foods containing the essential vitamin. This fact is of paramount diagnostic importance.

Treatment of diseases caused by nicotine deficiency

After confirming that the cause of the disease is a lack of an element such as nicotine, injections will be most effective method treatment. This is due to the fact that nicotinic acid injections begin to act very quickly without causing irritating effect on gastrointestinal tract, which is typical for tablets. However long-term use The drug, as well as its increased doses, can cause harm to the body. It has been proven that vitamin PP prevents the body from absorbing methionine, and this entails the occurrence of another disease. Therefore, it is recommended that during injections of nicotinic acid, enrich the diet with foods that have high content methionine, - cottage cheese, milk, cheese, eggs, fresh fish, soy products and meat.

Nicotinic acid (injections)

Nicotinic acid (injections) is a specific antipellagritic agent. In this regard, the drug is designated "PP-vitamin". Nicotinic acid (injections) when used on initial stages pellagra helps eliminate its phenomena.

In addition to antipellagric properties, vitamin PP helps improve carbohydrate metabolism, renders positive impact for mild forms of diabetes, heart disease, liver disease, peptic ulcer in the duodenum and stomach, and enterocolitis. Nicotinic acid (injections) has a vasodilating property and also promotes wound healing.

PP vitamin has a lipoproteinemic effect, reducing the level of lipoproteins in the blood.

Nicotinic acid (injections) helps normalize the functioning of the brain and nervous system. In addition, its positive impact on cardiovascular system, digestion. Nicotinic acid for the skin is one of the main helpers in maintaining it in healthy condition. In addition, the PP vitamin helps ensure normal vision, participates in improving blood circulation, reducing high blood pressure in the blood due to its vasodilating properties.

Nicotinic acid for lactation is a stimulant. Vitamin PP is involved in vascular blood supply and acceleration of blood circulation in the mammary gland.

The drug is available in ampoules.

For ischemic stroke, PP vitamin is administered intravenously. The dosage is one milliliter of a one percent solution.

Intravenous administration must be done slowly. Fast intravenous administration solution can provoke a significant decrease in blood pressure. Intramuscular and subcutaneous administration of nicotinic acid causes pain.

Taking the drug orally (in the form of powder or tablets), in particular, on an empty stomach or by persons with hypersensitivity, can cause dizziness, redness of the upper body and face, a feeling of a rush of blood to the head, paresthesia (numbness in the extremities), and a nettle rash. As practice shows, these manifestations are eliminated on their own after a certain period of time.

The intravenous drug is contraindicated in persons with hypertension in severe form (with a pronounced persistent increase in blood pressure) and atherosclerosis.

If identified hypersensitivity to nicotinic acid, it is recommended to replace the drug with nicotinamide. An exception may be when the drug is used as a vasodilator.

In order to increase lactation, the drug is prescribed fifty milligrams orally up to three times a day, ten to fifteen minutes before breastfeeding.

When prescribing during lactation, it is necessary to warn the patient about possible reaction short-term (redness on the face and upper body, feeling of fullness mammary glands, V in rare cases itching). The administration of nicotinic acid is recommended in combination with ascorbic acid.

It should be noted that long-term use Vitamin PP in large doses can provoke the development of fatty liver degeneration. In order to prevent this complication You should include foods rich in methionine (an amino acid that is not synthesized in the body) in your diet, or prescribe methionine and other lipotropic (selectively interacting with fats) agents.

dandruff,

slow hair growth

However, it also has contraindications and can lead to severe redness scalp, itching, headache and dizziness if:

you are prone to allergies, urticaria, and intolerance to certain drugs;
you suffer at least sometimes from high blood pressure.

The harm of nicotinic acid can be manifested by the appearance of side effects: severe irritation scalp, as well as dizziness and headache. In this case, immediately wash the drug off your head!

Gross formula

C6H5NO3

Pharmacological group of the substance Nicotinic acid

Nosological classification (ICD-10)

CAS Code

59-67-6

Characteristics of the substance Nicotinic acid

White crystalline powder, odorless, slightly acidic taste. Difficult to dissolve in cold water(1:70), preferably hot (1:15), slightly soluble in ethanol, very slightly soluble in ether.

Pharmacology

pharmachologic effect- hypocholesterolemic, hypolipidemic, vasodilating, replenishing vitamin PP deficiency (B 3).

Included in the prosthetic group of enzymes that are hydrogen carriers: nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), regulates redox processes, tissue respiration, protein and fat synthesis, glycogen breakdown.

Inhibits lipolysis in adipose tissue, reduces the rate of VLDL synthesis. Normalizes blood lipid composition: reduces the level total cholesterol, LDL, triglycerides and increases HDL level, has antiatherogenic properties. Has a vasodilating effect, incl. on cerebral vessels, improves microcirculation, increases fibrinolytic activity of the blood and reduces platelet aggregation (reduces the formation of thromboxane A 2).

Promotes the transition of the trans-form of retinol to the cis-form used in the synthesis of rhodopsin. Promotes the release of histamine from the depot and activation of the kinin system.

Has detoxifying properties. Shows effectiveness in Hartnup's disease - a hereditary disorder of tryptophan metabolism (absorption and penetration into tissues), accompanied by a deficiency in the synthesis of nicotinic acid.

Well absorbed in the pyloric region of the stomach and upper sections duodenum. Partially biotransformed in the liver with the formation of N-methylnicotinamide, methylpyridonecarboxamides, glucuronide and a complex with glycine. It is excreted in the urine, mainly unchanged.

Application of the substance Nicotinic acid

Prevention and treatment of pellagra (vitaminosis PP); atherosclerosis, hyperlipidemia (including hypercholesterolemia, hypertriglyceridemia), spasm peripheral vessels, incl. obliterating endarteritis, Raynaud's disease, migraine, cerebrovascular accident, including ischemic stroke (complex therapy), angina pectoris, Hartnup disease, hypercoagulation, facial neuritis, long-term intoxication non-healing wounds, ulcers, infectious diseases, gastrointestinal diseases.

Contraindications

Hypersensitivity, peptic ulcer of the stomach and duodenum (in the acute stage), severe liver dysfunction, gout, hyperuricemia, severe forms arterial hypertension and atherosclerosis (iv administration).

Restrictions on use

Pregnancy, breastfeeding.

Use during pregnancy and breastfeeding

Use caution during pregnancy and breastfeeding (take high doses contraindicated).

Side effects of the substance Nicotinic acid

Caused by the release of histamine: redness of the skin, incl. faces and upper half torso with a tingling and burning sensation, a feeling of a rush of blood to the head, dizziness, hypotension, orthostatic hypotension(with rapid intravenous administration), increased secretion of gastric juice, itching, dyspepsia, urticaria.

With long-term use of large doses: diarrhea, anorexia, vomiting, liver dysfunction, fatty degeneration liver, ulceration of the gastric mucosa, arrhythmia, paresthesia, hyperuricemia, decreased glucose tolerance, hyperglycemia, transient increase in the activity of AST, LDH, alkaline phosphatase, irritation of the gastrointestinal mucosa.

Interaction

Potentiates the effect of fibrinolytic agents, antispasmodics and cardiac glycosides, toxic effect alcohol on the liver. Reduces the absorption of sequestrants bile acids(an interval of 1.5-2 hours between doses is required) and the hypoglycemic effect of antidiabetic drugs. Possible interaction with antihypertensive drugs, acetylsalicylic acid, anticoagulants.

Routes of administration

Inside, IV, IM, s/c.

Precautions for the substance Nicotinic acid

During treatment, liver function should be regularly monitored (especially when taking high doses). To prevent hepatotoxicity, it is necessary to include foods rich in methionine (cottage cheese) in the diet, or prescribe methionine or other lipotropic agents.

Use with caution for hyperacid gastritis, gastric and duodenal ulcers (in remission) due to the irritating effect on the mucous membrane (taking large doses in this case is contraindicated). Taking large doses is also contraindicated for liver diseases, incl. hepatitis, cirrhosis (possibility of hepatotoxicity), diabetes mellitus.

August 27, 2018

In the treatment of many ailments in complex therapy nicotinic acid is prescribed. The benefits and harms to our health of this vitamin will, first of all, depend on the correct use of it. Let's figure out when you can and even need to take niacin.

Let us immediately note that any drug, even one belonging to the group of vitamins, should be taken only in consultation with the treating specialist. Vitamin PP is no exception. The instructions for the drug contain indications for its use. The range of diseases for which niacin helps is quite wide.

“Nicotine” affects the body as follows:

normalizes metabolic processes;
helps restore the structure of neural fibers;
improves blood circulation processes;
strengthens the immune system;
improves oxygen exchange by dilating blood vessels;
displays toxic substances from the body.

Indications for the use of vitamin PP:

weakened visual function;
alcohol, food poisoning;
poor blood circulation in the brain and also in the limbs;
manifestations of osteochondrosis;
ischemic stroke;
hemorrhoidal cones;
constant noise in the ears;
liver diseases;
disturbances in metabolic processes;
diabetes;
migraine;
high stomach acidity.

On a note! Nicotinic acid is especially indicated for pellagra - a lack of niacin in the body. But even in this case, you must first consult a doctor.

Vitamin PP, unlike many of its “brothers”, is able to provide oxygen to the blood and also prolong youth. Nicotinic acid is beneficial for our curls, skin and nail plates. It will also improve memory and increase attention.

Who should not take niacin?

The list of contraindications to the use of vitamin PP is also quite wide. These include peptic ulcer stomach and an allergic reaction to the components of the product. Nicotinic acid is harmful to the liver if a person is diagnosed with cirrhosis. It is not recommended to take niacin in case of atherosclerosis, severe glaucoma, bleeding, gout, as well as high rate contains uric acid in the blood.

Injections of nicotinic acid will not bring benefit, but harm, if administered intravenously with frequent pressure surges. And such manipulations are prohibited for women carrying a baby and breastfeeding. This is due to the fact that vitamin PP has a number of possible side effects.

Side effects of niacin:

pressure drop;
throwing into a fever (this goes away quickly);
aggravation clinical picture for stomach ailments;
dizziness;
redness appearing in the upper body or face.

Attention! Reduce manifestation side effects introducing cottage cheese to the menu will help.

Separately, it is necessary to dwell on the benefits and harms of nicotinic acid for women. It is used to accelerate growth hairline, skin improvement and even weight loss.

Growing gorgeous hair

Nicotinic acid has exceptional benefits for hair, and there will be no harm to our curls from such a drug. The main thing is to use it correctly. Niacin is the first assistant metabolic processes in organism. If he enters sufficient quantity, not only will the functioning of our organs improve, but also our appearance will improve.

Masks with niacin stimulate hair growth by dilating blood vessels on the scalp. How to make them? The easiest way is to add a couple of drops of the drug to a regular balm or shampoo. You can also rub the vitamin into the scalp. This will protect against dandruff and baldness.

Mask for accelerated growth and hair health:

Take one ampoule of niacin and combine it with half a tablespoon of aloe juice. If you have long hair, increase the amount of components proportionally.
Apply the prepared mass to the scalp.
Wrap your head in something warm. We wait forty minutes.
Then we wash our hair with shampoo.
We repeat the procedure two to three times a week for a month. During this time, the hair will become thicker and longer.
After three weeks you can repeat the course.

Attention! For allergies, nicotinic acid is harmful to hair. If you feel itching or dizziness, wash off the mask immediately!

Rejuvenate your face

Nicotinic acid helps the skin of our face to fully “breathe”. If there is not enough of it in the body, skin become dry and look dull. Rashes may also appear of various nature and peeling. Add niacin to face creams or lotions. Just check first to see if your skin responds allergic reaction on him.

We fight excess weight

And here nicotinic acid can help, because it improves the digestive process and normalizes hormonal background. Niacin will also lower cholesterol levels and promote the production of gastric secretions. In addition, it will cleanse our body of toxins.

Nicotinic acid will help lift the mood of people who spend their energy in the fight against extra pounds, due to increased production of the hormone serotonin. Accordingly, the craving for sweets will disappear, which, as we know, tends to increase during stress.

Moreover, as soon as the first signal about the production of the “happiness” hormone reaches the cerebral cortex, our body will immediately stop demanding carbohydrates, and they are the ones that most often cause obesity. But when such impulses stop, the body again suffers from a lack of carbohydrates and begins to “demand” them.

On a note! Pet lovers are interested in what nicotinic acid brings to cats. Its harm and benefits for a pet will not differ from those for a person. This vitamin can often be found in various food additives for animals.

If you notice loss of appetite, muscle weakness, as well as gastrointestinal ailments or skin problems, most likely your body does not have enough nicotinic acid. Its reserves can be replenished not only by taking the drug, but also by eating food.

Foods that contain niacin:

offal - kidneys and liver;
meat products;
fish;
egg yolks;
dairy products;
cheeses of different varieties;
sunflower seeds;
mushrooms;
sprouted wheat;
buckwheat.

On a note! During heat treatment, the amount of nicotinic acid in products is reduced by only twenty percent.