The consequences of sildenafil. Vardenafil or sildenafil which is better

Education: Graduated from the Sverdlovsk Medical School (1968 - 1971) with a degree in Paramedic. Graduated from Donetsk medical school(1975 - 1981) with a degree in “Epidemiologist, Hygienist”. He completed his postgraduate studies at the Central Research Institute of Epidemiology in Moscow (1986 - 1989). Academic degree - candidate medical sciences(degree awarded in 1989, defense - Central Research Institute epidemiology, Moscow). Completed numerous advanced training courses in epidemiology and infectious diseases.

Experience: Work as head of the department of disinfection and sterilization 1981 - 1992. Working as a department head dangerous infections 1992 - 2010 Teaching activity at the Medical Institute 2010 - 2013

NOTE! Information about medications on the site is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment. Before using the drug Sildenafil, be sure to consult with your doctor.

Vladimir | 0:32 | 13.11.2017

I agree that sildenafil is one of the safest substances for erection, it’s good that now you can choose the drug for yourself based on the price, I buy Viatile, 50 mg is the optimal dose for me at a time. By the way, anyone who thinks that they will take these pills and their penis will stand up on its own is very mistaken; it won’t work without a woman’s affection.

Nikolay | 21:32 | 22.10.2017

Sildenafil is fine, it works. But suddenly, if you took it, but there was no sex, the hard-on will torture you for a day))) Normal drug. At first I used Dynamico, but then they recommended an analogue, ours. There are more tablets, but the price is several times cheaper. And you need to trust ours!!!

The drug Sildenafil is widely used in the treatment of erectile dysfunction in men. different manufacturers. Chemical compound, which is the active ingredient of the drug, has high activity and can affect the functioning of other organs and systems. Therefore, the instructions for use contained in the article should be studied before starting treatment. Current prices, reviews from doctors and patients, as well as analogs of Sildenafil in Russia that can replace the drug will complement patients’ understanding of the drug.

Compound

The drug contains Sildenafil (Sildenafilum - this is in Latin international name) contains the active substance Sildenafil citrate in dosages of 25, 50 or 100 mg.

Auxiliary components used by manufacturers are cellulose, povidones, dyes, macrogols, Mg stearates, Ti oxides.

Release form

The medication is available in the form of film-coated tablets intended for oral administration. blue color. Each tablet has oval shape. On one side there are engravings indicating the dose of Sildenafil.

Packages are produced that contain 1, 2, 4, 8, 10, 14 or 20 tablets, as well as official instructions on the use of the medicine.

pharmachologic effect

Sildenafil is a representative pharmacological groups drugs intended for the treatment of erectile dysfunction. The mechanism of action of the drug is based on enhancing the synthesis of NO. Thanks to this, the following types of pharmacological action are achieved:

• relaxation of vascular walls;
• increased blood supply to the penis;
• slowing down the reverse flow of blood from the penis;
• decrease in pressure in blood vessels. It is important to use with caution in patients being treated for hypertension, including pulmonary hypertension;
• Helps maintain an erection throughout sexual intercourse.

Important! Sildenafil is used to cause an erection and begins to act only in the event of sexual stimulation.

Indications for use

The following deviations and conditions are given as indications for use:

• lack of ability to achieve an erection;
• inability to save normal erection all sexual intercourse.

Contraindications

Sildenafil is not prescribed if there is the following pathologies and conditions that are contraindications for use:

• allergy to medicine;
• permanent or temporary intake of nitrates;
• diseases for which it is recommended to limit sexual activity;
• children under 18 years of age. Sildenafil is not used in childhood;
• women. Treatment with Sildenafil is not carried out in women, as well as during breastfeeding (lactation) and pregnancy;
• severe liver disease;
• stroke or heart attack diagnosed in the last six months;
• congenital retinal abnormalities;
• defects in the formation of the penis (congenital and acquired);
• loss of vision due to ischemia.

Before prescribing the drug, it is important to exclude these contraindications.

Instructions for use

It is important to remember that sexual arousal is required for the drug to be effective.

Mode of application:

The tablet is taken only orally, washed down with a small amount clean water. According to the manufacturers' description, the medicine is more effective if taken before meals. Food, especially fatty foods, significantly slows down the onset of the drug’s effect. The drug is taken 40-60 minutes before the planned contact at any time of the day - in the evening (after lunch), during the day or in the morning (before lunch).

Important! Maximum dose per day - 100 mg.

Potency pills do not have a clear course of treatment. Take only as needed, but not more than once every 24 hours. The duration of administration, subject to the recommended regimen, is selected by the doctor according to the patient’s condition.

The duration of action of Sildenafil is up to four hours. The first effects appear half an hour after application.

Overdose

The consequences of a drug overdose (according to the manufacturers' instructions) may be an increase in the frequency of side effects and their severity. Assistance to the victim is only symptomatic.

Side effects

Side effects when taking Sildenafil develop quite often. Select a row adverse reactions, which are more severe, but develop much less frequently.

Frequent adverse reactions:

• headache;
• swelling of the face;
• hot flashes (redness of the face, feeling of heat);
• dizziness;
• swelling of the nasopharynx, resulting in nasal congestion;
• decreased visual acuity;
• digestive disorders;
• color perception disorders.

If such abnormalities develop, contacting a doctor is required only in severe cases.

Rare side effects:

• erection that does not go away for a long time;
• painful erection;
• chest pain;
• inflammation and muscle soreness.

As a rule, such disorders are observed when the dosage regimen is not followed and the dose is exceeded. An important way prevention of these complications is the absence of self-medication and compliance with the recommended rules for taking and dosing Sildenafil. Addiction to the drug does not develop.

Interaction with other tools

When taking nitrate medications, treatment with Sildenafil is contraindicated. When they are combined, the effects of the drugs are enhanced.

Sildenafil enhances the effectiveness of blood pressure-lowering drugs. If these drugs are compatible, severe hypotension may develop.

The combination with the following drugs leads to an increase in the level of Sildenafil in the blood, an increase in its toxicity and the frequency of side effects:

• Cimetidine;
• Erythromycin;
• Ketoconazole (in tablet form);
• Itraconazole (tablets);
• Antiviral agents;
• Nicorandil;
• antiparkinsonian (Vertinex, Levodopa).

During pregnancy and lactation

Sildenafil is not used in women, as well as in breastfeeding(GW) and during the period of bearing a child.

With alcohol

When Sildenafil interacts with alcohol, no dangerous adverse reactions develop. In any case, during treatment with Sildenafil, it is recommended to limit alcohol consumption, despite normal level compatibility not to provide increased load on the heart, blood vessels, liver and kidneys.

Analogs

Substitutes are any medicines based on Sildenafil - original drugs and generics. The list of such means is as follows:

Sildenafil differs from these drugs only by the manufacturer. In all other respects there is no difference or difference. These are equivalent means of domestic or foreign production that have a sufficient level clinical trials on efficiency and safety.

Important! Replacement of the drug with synonyms should only be carried out by the attending physician.

If necessary, Sildenafil can be replaced with products that are produced on the basis of other active substances from the same group of drugs:

Among such products, you can select cheaper analogues from Russian and other manufacturers.

Best before date

Sildenafil is suitable for use only for 3 years from the date of issue. After the specified expiration date has expired, the drug should not be taken.

Terms of sale and storage

Sildenafil should be stored in original packaging subject to the following conditions:

• temperature no more than 30⁰С;
• dry place;
• away from children;
• away from direct rays.

The drug is sold in pharmacies according to prescriptions from a doctor, who must prescribe them in Latin.

special instructions

Because the medicine causes dizziness and disturbances visual functions, it is important to find out your reaction before driving and operating other mechanisms that require precision and increased concentration.

Many patients over 60 years of age are recommended to start treatment with a dose of Sildenafil 25 mg.

For patients with concomitant serious pathologies of the liver and kidneys, the recommended initial dose is 25 mg. If well tolerated, the dose can be increased to 50 or 100 mg (rarely).

Sildenafil is used only in adult men.

Price

Sildenafil produced by North Star is cheaper. The cost of the same drug from other manufacturers is slightly more expensive. Sildenafil can be bought in pharmacies at the following price:

• 25 mg No. 1 - from 52 rubles;
• 25 mg No. 4 - from 110 rubles;
• 25 mg No. 20 - from 319 rubles;
• 50 mg No. 1 - from 65 rubles;
• 50 mg No. 2 - from 110 rubles;
• 50 mg No. 4 - from 160 rubles;
• 50 mg No. 10 - from 363 rubles;
• 50 mg No. 14 - from 400 rubles;
• 100 mg No. 1 - from 65 rubles;
• 100 mg No. 2 - from 200 rubles;
• 100 mg No. 4 - from 240 rubles;
• 100 mg No. 8 - from 365 rubles;
• 100 mg No. 10 - from 400 rubles;
• 100 mg No. 20 - from 678 rub.

The problem of erectile dysfunction occurs in many men. The reasons for this phenomenon can be different: from psychological to medicinal. But how can you restore intimacy with your spouse or girlfriend if an erection does not occur? In this case, the drug “Sildenafil” will come to the rescue, in which the active element is a substance with the same name - sildenafil. The use of this medication, its cost, detailed composition - all this will be discussed in the article. We will also find out what analogues this drug has.

Compound

Sildenafil contains the following components:

Active ingredient: 25, 50 or 100 mg of sildenafil citrate.

Auxiliary components: lactose monohydrate, colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, hyprolose.

This medication is available in 25, 50 and 100 mg.

Application

It is advisable to take Sildenafil 1 hour before the planned sex. The effect of this medication begins only with sexual arousal, so there is no need to be afraid of its untimely effect. If sexual desire no, then an erection will not occur either, so this saves the person from any awkward situations.

The initial dose of the drug should be 25-50 mg once a day. If necessary, the doctor can increase the intake to a maximum of 100 mg per day. The exposure time is 5 hours.

The medicine is effective throughout intimacy. After 5 hours of exposure to the product, the erection goes away naturally. If you want to make love again, then sexual arousal occurs again, and no additional pills are required.

Patented drug "Viagra"

This drug was the first medicine to contain sildenafil as an active ingredient. "Viagra" - a drug international standard, still produced today, but the cost original tablet 2 or even 4 times higher than that of generics (products sold under the international proprietary name, but different from the brand name of the drug manufacturer). All pills that contain sildenafil as an active element are considered to be some kind of copies of the original. This also happened with the drug to which the article is devoted. Generic Sildenafil, a medicine that differs from the famous Viagra in the composition of auxiliary components, is called a “dirty” medicine by many pharmacists. This is due to the fact that for its production substances are taken that have not been scrupulously purified from impurities. The same cannot be said about Viagra tablets.

The drug "Sildenafil": use in medicine

This remedy helps to cope with the inability to maintain an erection sufficient for high-quality, satisfactory sex. The reasons for its violation can be different: organic, psychogenic, mixed. The drug will also be effective for impotence. The action of the product will give positive result only in combination with sexual stimulation.

Price

The drug "Sildenafil", analogues of which have different prices, can be purchased at any pharmacy. This is a widely used remedy that helps men restore their sex life. The price of this medication is not fixed, since it depends on several criteria: the number of tablets in the package, the dosage of the pills, the location of the pharmacy and its markup. On average, the cost of 10 pills of 50 mg will cost 550 rubles. If you buy tablets in the same quantity, but 100 mg each, then the drug will cost more: the price will be about 830 rubles. And for 4 pills of 25 mg each you will need to pay approximately 280 rubles.

The drug "Sildenafil": analogues

Oddly enough, although this drug is a copy of Viagra, it also has drugs that are similar in action. Today there is sufficient quantity drugs that can replace generic Sildenafil, a drug for erectile dysfunction. So, its analogues are the following drugs: “Cialis”, “Levitra”, “Impaza”, “Sealex”, “Tribestan”, “Laveron”, “Viardot Forte”, etc. Although these drugs have different composition, however, have a similar effect as Sildenafil tablets.

The drug "Cialis"

Although this medication is considered an analogue of the drug Sildenafil, its composition is different. Thus, Cialis tablets consist of the following elements: active substance- tadalafil, auxiliary components- lactose monohydrate, hyprolose, MCC, croscarmellose sodium, magnesium stearate.

This drug helps men cope with erectile dysfunction, as well as get rid of symptoms of lower urinary tract in patients with benign prostatic hyperplasia.

Cialis tablets must be taken orally. Men who make love more than 2 times a week are recommended to take 1 5 mg pill once a day, at the same time. If representatives of the stronger sex have sex less often than 2 times a week, then it is advisable to swallow a tablet in a dose of 20 mg immediately before intimacy.

The cost of Cialis may vary and depends on the number of pills in the package. So, on average, for 10 tablets of 20 mg you need to pay 1,500 rubles. It turns out that one pill costs 150 rubles. If you buy 100 tablets, then the price will be 7,000 rubles. It turns out that in this case 1 pill will cost 70 rubles. This is 2 times cheaper than purchasing a package containing 10 tablets.

The drug "Impaza"

This is another medicine that can be a good competitor to Sildenafil. Analogues of this drug, as already indicated, may have a completely different composition, but the effect may be identical. This is what happens with the drug Impaza. This homeopathic remedy, which is prescribed to men with erectile dysfunction.

Impaza is also available in tablets. One pill contains the following components: active substances - antibodies to endothelial NO synthase, auxiliary elements - lactose monohydrate, magnesium stearate.

You need to take 1 tablet per day before or after meals. You cannot bite or swallow the pill; it must be kept in your mouth until completely dissolved. To stabilize potency, it is recommended to carry out a treatment and prophylactic course of at least 12 weeks. The doctor, together with the patient, can subsequently change the frequency of taking pills. He may even prescribe Impaza tablets to the man every other day. For occasional stimulation of erection, the drug is used 2 tablets 1 or 2 hours before intimacy.

Exciting drugs for women

Not only men can suffer from the fair sex, disorders can also overtake them sex life. Medicines containing sildenafil will also come to the aid of women. Female version The medicine is capable of accomplishing the following tasks:

Enhance sexual desire and increase libido (including in older ladies).

Reduce the time required for strong sexual arousal.

Increase sensitivity.

Improve blood flow in the pelvic organs.

Increase vaginal lubrication.

Increase stamina during lovemaking.

Eliminate frigidity.

Sildenafil for women is produced under the following brands: Womenra, Ladygra, Cenforce FM, Femalegra.

Womenra tablets: description

The composition of these pills is as follows: the active ingredient is sildenafil citrate in doses of 50 and 100 mg. Additional items: croscarmellose sodium, calcium hydrogen phosphate, opadry rosea, microcrystalline cellulose.

These tablets must be taken orally. The initial dose should be 50 mg per day. You need to take the pill approximately 1 hour before the start of sexual activity. Subsequently, the dose can be increased with the doctor’s permission to 100 mg or, conversely, reduced to 25 mg (that is, half a tablet).

The cost of Womenra tablets may vary. The price depends on the dosage of pills and their total quantity in the package. So, on average, for 4 tablets of 50 mg you need to pay about 500 rubles.

Now you know basic information about the drug “Sildenafil”: analogues of this medication, its composition, scope of application. We found out that it is a generic version of the famous drug Viagra. However, the drug “Sildenafil” is several times cheaper than the original, which is why it is used more often.

When men have difficulty getting an erection, everyone reacts to the problem differently. Some people become isolated and ignore this fact, thinking that over time everything will work out on its own. Others rush to specialists, relying on medicine and pharmacology. Still others collect information on the Internet, or by asking friends for it. All three types are right in their research, and sooner or later everyone decides to try drugs to improve erectile function. Medicines of this type are sold without a prescription, which allows you to experiment with such indicators as price and speed. The most popular drug was and remains Viagra (the active substance is sildenafil). Therefore, we will answer the most common questions: what kind of drug is this, what dosages are considered normal and really help, how much does sildenafil cost, and how good are its analogs. It is important to find out what sildenafil reviews cause in men. Let's talk about all this right now.

How the drug appeared and its main effect

Almost any man can take sildenafil, regardless of age. The main effect is the fight against any manifestation of erectile dysfunction. Having a beneficial effect on blood circulation in the pelvic organs, the medicine makes it possible to fully engage in sexual intercourse. Penis hardness, renewed and increased desire, extraordinary brightness of sensations, increased friction and a powerful orgasm - all this will be provided by a small pill. Sildenafil is effective even in cases where dysfunction is caused by spinal injuries, diabetes mellitus and hormonal disorders. How did this remedy, unique in its action, come about?

• The end of the 70s of the last century - American scientists began experiments and research to create a drug that expands blood vessels. The goal was for the drug to act simultaneously in the brain, lung tissue and heart;
• Early 90s - during testing, a side effect was noted (improved erection and quality of sexual sensations in experimental subjects);
• 1998 – researchers are awarded Nobel Prize, the drug Viagra appears, and men all over the world get the opportunity to show their best side in sex.

In fact, sildenafil as an active substance stimulates the reaction male body for excitement. This component acts as a kind of intermediary in natural processes body. The action is due to the following relationships:

• During sexual arousal, nitric oxide is released;
• It dilates blood vessels and increases blood circulation in the cavernous bodies of the penis;
• The oxide, in turn, activates the creation of cyclic GMP molecules;
• Sildenafil destroys the natural enzyme that negatively affects these molecules, which allows the blood vessels to remain dilated longer;
• This entire interconnected structure allows the penis to remain erect longer.

It can be argued that the drug enhances the body's natural reactions. Men often ask the question “is sildenafil harmful?”, and in what quantities can it be taken? The answer is the reviews of doctors; we will talk about these aspects further.

Indications, contraindications and other medical recommendations

In addition to stimulating erectile function, the drug has an effect on the pulmonary blood vessels and arterial pressure. This important factor for men suffering from shortness of breath or other pathologies pulmonary system. Taking the pill improves quality of life and improves self-esteem. Some doctors insist that by taking sildenafil too often, a man creates psychological dependence from the drug. But other types of dependencies were not found in clinical trials. Let's move on to listing the advantages of the active substance.

Indications

A drug is needed to eliminate erectile dysfunction. The reasons for violations can be different, for example:

• Organic – associated with diseases (recurrent and chronic) occurring in the body, or with dysfunction of the hormonal, nervous and genitourinary systems;
• Psychogenic – associated with uncomfortable psychological state men. This condition is caused by overwork, stress, workload, conflicts in couples, unfulfilled sexual desires;
• Mixed - against the background of developing diseases or infections, observed psychological trauma or decreased self-esteem, depression.

Sildenafil also helps with injuries spinal column, for obesity and diabetes, problems with the prostate and nervous reactions. Therefore, to the question “is sildenafil harmful?” many experts answer in the negative, and do so based on the results of treating real patients.

Contraindications

You should not take the drug for stimulation if:

• At this time, you are prescribed nitrates or nitrites (for example, vasotropin or nitrosorbide);
• Other inhibitors must be taken;
• Reception prescribed medicines for the lungs;
• Recently had a heart attack or stroke;
• Eat congenital pathologies retina;
• Diagnosed in the body serious illness liver;
• An allergic reaction to the active substance was detected.

In some cases, taking the drug is not prohibited, but this must be done with caution, monitoring your own reaction and not exceeding the recommended dose. So, careful use of sildenafil is recommended:

• With Peyronie's disease;
• For myeloma and leukemia;
• With a reduced level of platelets (red blood cells);
• For deformities of the genital organ, congenital or acquired due to injury;
• For pathologies in the gastrointestinal tract, namely gastric and duodenal ulcers.

Sildenafil instructions for use, side effects

In order for the effect of the drug to be pleasant and controllable, it is necessary to answer the following questions:

• How to take it correctly medicine to increase potency?;
• Is sildenafil harmful in case of overdose, and is it possible in principle?;
• How long does the drug last?;
• What does the drug allow you to do, and how long does it take for pharmacokinetics (absorption of the active substance into the blood)?

Therefore, let's move on to a more detailed discussion of this popular and known remedy, to restore erectile function.

• Firstly, dosage form drug - tablets of 25, 50 and 100 mg.
• Secondly, it is the average that is considered standard. Already 25 mg are prescribed for use together with other drugs, and 100 mg is the maximum permissible dose per day.
• The original Viagra tablet is taken with a glass of water, approximately an hour before the intended sexual intercourse. For some men, this time may be reduced due to individual characteristics body.
• It is advisable to take the tablet on an empty stomach, since eating food lengthens the interval between administration and the onset of action. You should not drink it, it may neutralize the effect of the inhibitor. It is within an hour that the medicine is completely digestible and absorbed.
• An overdose can have a bad effect on general health. For example, lead to sinus congestion, soreness and tearing, shortness of breath and skin rashes. Only the consequences can be eliminated; it is not possible to remove the drug from the blood until the end of the pharmacological action.

“Side effects” can be expressed in different ways:

• Headaches and dizziness appear;
• An erection may be too long and therefore painful;
• The sensitivity of the skin increases;
• There is a rush of blood to the face.

It is these individual factors that force men to answer positively the question “is sildenafil harmful?” But oh medical opinion we already informed readers earlier.

Cost of the drug

How much does sildenafil cost on the Russian pharmacological market? It is difficult to answer unequivocally; the following factors play a role in this question:

• Who is the manufacturer of the drug;
• How many tablets are in the package;
• The original drug is offered for sale or only a generic version.

The original American drug Viagra costs about 1,000 rubles per tablet. Quality can be checked by the batch number, or by asking the pharmacy for product certificates. How much does generic sildenafil cost? In fact, three times less. This is due to the presence of cheaper additional ingredients in the tablet (but the active substance is necessarily present in the right quantity), and the absence of costs for developing and testing the drug before obtaining a production patent. Effect of original drug(and from generics) lasts at least 4-6 hours after oral administration inside. According to reviews, generics give more side effects than the original, but they are easily tolerated against the backdrop of a direct, pleasant result. Let's list several analogues of Viagra:

• Cialis, Levitra, Impaza;
• Tribestan, viardot, ali caps;
• Yohimbe, Laveron, Sealex;
• Furongbao super and himcolin.

Analogs

Already 3 years in European pharmaceutical market a miracle drug for restoring potency Semental appeared. It is several times more effective than Viagra - it not only gives an instant erection immediately after taking it, but also restores natural potency in men. At the same time, it has absolutely no side effects and costs 8 (!) times less. One of the most important advantages of Semental is that it not only does not harm the body, but also further improves its health. Also contains more than 10 potent natural ingredients, among which is L-arginine, for the discovery of which in 1998 three American scientists (Robert Farchgott, Louis Ignarro and Ferid Murad) received the Nobel Prize in medicine and physiology (strengthens the heart and blood vessels).