Glutamic acid 250 mg. Glutamic acid in bodybuilding

Glutamic acid - a non-essential amino acid involved in the processes of transamination of amino acids in the body. The nitrogen of most amino acids goes through stages of transformation into glutamine, aspartic acid or alpha alanine. Glutamic acid is involved in protein and carbohydrate metabolism, stimulates oxidative processes, promotes the neutralization and removal of ammonia from the body, and increases the body's resistance to hypoxia. Promotes the synthesis of acetylcholine and ATP, the transfer of potassium ions, plays important role in activities skeletal muscles.
Glutamic acid is a neurotransmitter amino acid that stimulates the transmission of excitation in the synapses of the central nervous system.

Pharmacokinetics

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Glutamic acid is well absorbed when taken orally. It is quickly eliminated from the blood, accumulating mainly in muscle and nervous tissues, in the liver and kidneys, penetrates the blood-brain barrier and cell membranes. During absorption, glutamic acid is partially transaminated to form alanine. Under the influence of the enzyme glutamate decarboxylase, it is converted into a neurotransmitter in the brain - gamma-aminobutyric acid. About 4-7% of it is excreted unchanged in the urine, the rest is utilized in the process of metabolic transformations.

Indications for use

Glutamic acid used in the treatment of epilepsy, mainly minor seizures with equivalents, somatogenic, involutional, intoxication psychoses, reactive states with symptoms of depression, exhaustion; when delayed mental development in children, Down's disease, cerebral palsy, polio (acute and recovery period s), with progressive myopathy, to eliminate and prevent neurotoxic phenomena that may occur when using isoniazid and other drugs of the isonicotinic acid hydrazide group.

Mode of application

For adults Glutamic acid prescribed in a single dose of 1 g 2-3 times a day.
For children single doses are: at the age of 3-6 years - 0.25 g, 7-9 years - 0.5-1 g; at the age of 10 years and older - 1 g. Frequency of administration - 2-3 times a day.
For oligophrenia, 0.1-0.2 g per kg of the patient’s body weight is prescribed for several months.
Take 15-30 minutes before meals, if dyspeptic symptoms develop - during or after meals.
The course of treatment is from 1-2 to 6-12 months.

Side effects

Possible vomiting loose stool, increased excitability, insomnia.
At long-term use a decrease in hemoglobin content and leukopenia are possible.

Contraindications:
Contraindications for use Glutamic acid are: febrile conditions, increased excitability, pronounced psychotic reactions, hepatic and/or renal failure, nephrotic syndrome, peptic ulcer stomach and duodenum, diseases of the hematopoietic organs, anemia, leukopenia; childhood up to 3 years.

Interaction with other drugs

In combination with thiamine and pyridoxine Glutamic acid used for the prevention and treatment of neurotoxic phenomena caused by isonicotinic acid hydrazide preparations (isoniazid, ftivazide, etc.).
For myopathy and muscular dystrophy Glutamic acid is more effective in combination with pachycarpine or glycol.

Overdose

In case of overdose Glutamic acid the manifestations of the described side effects may increase.

Storage conditions

In the original container at a temperature not exceeding 25 ° C. Keep out of the reach of children. Shelf life: 4 years.

Release form

Film-coated tablets.
Packaging: 10 tablets in a blister.
10 tablets in a blister; 3 blisters per pack.

Compound:
1 tablet Glutamic acid contains L-glutamic acid 0.25 g (250 mg).
Excipients: povidone, calcium stearate, stearic acid, potato starch, sugar, light magnesium carbonate, anhydrous colloidal silicon dioxide, talc, titanium dioxide (E 171), proprietary blue V dye (E 131), yellow wax, light mineral oil.

Additionally

During treatment, it is necessary to systematically conduct urine and blood tests.
Whenever adverse reactions it is recommended to reduce the dose of the drug.
Glutamic acid is also used to relieve neurotoxic effects associated with taking other drugs.
After taking Glutamic acid, you should rinse your mouth weak solution sodium bicarbonate.

Main settings

Name:	GLUTAMIC ACID
ATX code:	N07XX10 -

Glutamic acid is a non-essential amino acid that plays an important role in protein metabolism, nitrogen metabolism, and redox processes occurring in the brain.

pharmachologic effect

Glutamic acid is aliphatic amino acid, which is present in the human body both in free form and as part of proteins and some low-molecular substances.

Glutamic acid is one of the components of myofibrils that provide contraction of muscle fibers; it is also involved in the synthesis of urea (the end product of metabolism), ATP (a nucleotide that plays an important role in metabolism and energy), acetylcholine (carries out neuromuscular transmission) and other amino acids .

Glutamic acid plays an important role in the transport and maintenance of the required level of potassium ions in the brain, normalizes the results of glycolysis (the process of breaking down glucose in cells) in the blood, and connects the metabolism of carbohydrates and nucleic acids.

The use of glutamic acid allows you to normalize metabolism, affecting functional state endocrine and nervous systems, stimulate the transmission of excitation, increase the body's resistance to oxygen deficiency, accelerate the neutralization and removal of ammonia from the body.

Reviews about Glutamic acid and clinical researches indicate that this amino acid has hepatoprotective properties, that is, it helps restore and cleanse the liver, and also suppresses the secretory function of the stomach

Indications for use of Glutamic acid

Glutamic acid, the instructions confirm, is effective for:

diseases of the nervous system;
psychosis;
epilepsy;
mental disorders manifested in the form of depression, insomnia, mental exhaustion;
consequences of meningitis and encephalitis;
developmental delays in children;
cerebral palsy
Down syndrome;
polio (acute infection, which is characterized by movement disorders);
toxic neuropathy.

Instructions for use of Glutamic acid

Glutamic acid, which should only be used as prescribed by a physician, is available in the form of powder, enteric-coated tablets, film-coated tablets, and granules for oral suspension.

According to the instructions, Glutamic acid should be taken 2-3 times a day 15-30 minutes before meals.

If dyspeptic symptoms develop, the drug must be taken during or after meals.

The recommended dose of Glutamic acid is: adults and children over 10 years old – 1 g, children 7-9 years old – 0.5-1 g, children 5-6 years old – 0.4 g, children 3-4 years old – 0.25 g , children 1-3 years old - 0.15 g, children under 1 year old - 0.1 g.

Side effects

Despite the fact that glutamic acid, reviews confirm, is well tolerated, in some cases such unwanted reactions on the use of the drug such as abdominal pain, diarrhea, vomiting, nausea, allergic reactions, increased excitability.

Long-term use of glutamic acid can cause leukopenia, anemia, cracks in the lips, and irritation of the oral mucosa.

Contraindications to the use of Glutamic acid

The instructions for Glutamic acid prohibit the use of the drug for:

hypersensitivity;
liver or kidney failure;
febrile syndrome;
peptic ulcer;
leukopenia;
anemia;
rapidly occurring psychotic reactions;
increased excitability;
nephrotic syndrome;
obesity;
inhibition of bone marrow hematopoiesis.

Glutamic acid should be prescribed with caution to patients with liver disease.

Additional Information

While using Glutamic acid, regular blood and urine tests should be performed. The drug should be stored at room temperature in a dark place. The shelf life of Glutamic acid is 3 years.

Sincerely,

Well known to many athletes and people who lead healthy image life, the neurotransmitter glutamine amino acid, is an amino acid replaceable for the human body, but very important in many metabolic processes, especially proteins. Tablets containing this neurotransmitter are also used to treat a number of central nervous system diseases.

What is glutamic acid

Chemical formula glutamic acid contains two double bonds, which indicate that this compound readily reacts with many organic substances: This dicarboxylic acid is capable of removing dangerous toxic metabolic products such as ammonia. The action and role of glutamate (a salt of the glutamic amino acid) for the human body cannot be overestimated, because as a neurotransmitter it is involved in nerve impulse, volumetric neurotransmission; in addition, this substance is involved in brain development.

What foods contain glutamic acid?

The neurotransmitter glutamic acid (designated as E620) is found in proteins, phosphatides in a free state and in the form of salts that are better absorbed: ammonium glutamate E624, potassium glutamate E622, calcium diglutamate E623, monosodium glutamate E621, magnesium glutamate E625. Free glutamic acid is found in such natural products:

green pea;
corn;
Green pepper;
eggs;
beef;
fatty fish (mackerel, mackerel, cod, trout);
spinach;
tomatoes;
cheese, milk;
carrots, beets.

Modern food industry cannot do without the use of glutamine as food additives into products instant cooking, semi-finished products, ready-made culinary products, broth concentrates, deli meats, boiled sausages. The popular dicarboxylic acid is used as a flavor enhancer - it gives products a pronounced meaty taste, enhances the aroma of meat, stimulates appetite and can be addictive.

Glutamic acid - instructions

You can find medications containing glutamine at the pharmacy and take it for the purposes you need. But it is important to remember that an excess of such a substance can provide the opposite effect to the expected effect: accumulating in the intercellular space, leading to early death nerve cells, also causes obesity, heart problems and metabolic processes. The instructions for glutamic acid contain information about required dosage, indications and contraindications for use, which are important to familiarize yourself with before starting use.

Glutamic acid - indications for use

Important structural element nitrogen metabolism, the “stimulating” amino acid has its own indications and contraindications. In medicine it is used to treat diseases of the central nervous system; indications for the use of glutamic acid may be:

schizophrenia;
depression;
epilepsy;
consequences of meningitis, encephalitis;
nervous exhaustion;
psychoses;
protein metabolism disorder;
myopathy.

How to take glutamic acid

The release form of glutamine is film-coated tablets with different dosages, powder. Before starting treatment, read the instructions on how to take glutamic acid. This medicine is prescribed by a doctor after an examination and, depending on the disease, the course of treatment can range from 2 months to a year. Take tablets before or during meals, and the dosage of the drug depends on the diagnosis, age and weight of the person:

infants up to one year of age – 100 mg;
1-2 years – 150 mg;
3-4 years – 250 mg;
5-6 years – 400 mg;
7-9 years – 500 mg;
10 years and older – 1000 mg.

Glutamic acid - contraindications

Athletes and people who are trying to lose weight prescribe amino acids on their own, but such actions can be dangerous for your body, because, like others medicines There are contraindications for glutamic acid. After identifying symptoms that you think can be eliminated with this drug, you should not self-medicate. In most cases, the amino acid described above can be completely synthesized by the body and supplied with food, but the harm from self-medication with it can be significant if you have:

obesity;
renal, liver failure;
increased excitability;
stomach ulcer;
anemia;
nephrotic syndrome;
fever;
suppression of bone marrow hematopoiesis.

Glutamic acid in sports

There are acids that are replaceable for the body an indispensable assistant for people involved different types sports Glutamic acid is useful for athletes because it facilitates pain syndrome in muscles after training, removing decay products from tissues, makes muscle fibers more susceptible to the penetration of potassium into them. Glutamic acid in bodybuilding helps to gain weight quickly muscle mass, and due to its ability to accelerate protein metabolism and remove ammonia, the need for glutamine for bodybuilders is much higher than for other people.

Glutamic acid for weight gain

Glutamic acid alone will not help you gain weight, but no muscle gain course should be completed without it. Why is glutamine so important? The first thing that is important when gaining weight is stimulation of metabolism, and for this the cells need good food spectrum of amino acids, and converts glutamine into other amino acids quickly and efficiently. In addition to accelerating exchange rates, oxidative processes, a non-essential amino acid that can boost immunity and make weight gain healthy.

Glutamic acid for children

L-glutamine is one of the few drugs that can be prescribed to a child under one year of age. The drug helps to cope with many serious childhood illnesses and disorders. Glutamic acid is prescribed to children for:

oligophrenia;
Down's disease;
consequences of birth intracranial injury;
mental retardation;
cerebral palsy;
polio.

Glutamic acid price

Order inexpensively this drug You can visit online pharmacies by studying product catalogs. According to reviews, it is easy to buy large volumes of L-glutamine for sports purposes in an online store. The price of glutamic acid varies from 15 to 75 rubles per package of tablets with a dosage of 250 mg (10 pcs.). Cost per specialized drugs For sports nutrition containing glutamine does not compare favorably with pharmacy products, the price of which is tens of times lower.

Video

Glutamic acid - reviews

Irina, 25 years old

A gynecologist prescribed a course of this amino acid to me when I was planning a pregnancy. Before drinking, I studied reviews on the Internet, most of which were positive. During the reception I did not feel any side effects, and then full course menstrual cycle became much more stable, without delays.

Alina, 28 years old

My husband is involved in bodybuilding and he drinks L-glutamine almost constantly. He orders the drug in pharmacies, and not on sports nutrition websites - everything is very expensive there, and no difference in composition was found. His trainer advised him to take the drug, side effects I haven’t had one since I started, so I’m not worried about my husband’s health.

Margarita, 40 years old

When due serious problems At work I went to see a neurologist, it turned out that I had serious nervous exhaustion, vegetative-vascular dystonia, lost on nervous soil almost 7 kg. I was treated with antidepressants and was prescribed many more vitamins and glutamic acid, which I still take on the doctor’s recommendation to gain weight.

Glutamic acid

Composition and release form of the drug

◊ Film-coated tablets white or white with a barely noticeable yellowish tint, round, biconvex; On a cross section, two layers are visible.

Excipients: potato starch 28.1 mg, 8.4 mg, talc 6 mg, calcium stearate monohydrate 2.4 mg.

Film shell composition: sucrose 89.305 mg, talc 3.933 mg, titanium dioxide 2.573 mg, povidone 2.018 mg, colloidal silicon dioxide 2.115 mg, beeswax 0.028 mg, liquid paraffin 0.028 g.

10 pieces. - contour cellular packaging (aluminum/PVC) (6) - cardboard packs.
60 pcs. - polymer jars (1) - cardboard packs.

pharmachologic effect

A drug that improves brain metabolism. An essential amino acid plays the role of a mediator with high metabolic activity in the brain, stimulates redox processes in the brain and protein metabolism. Normalizes metabolism, changing the functional state of the nervous and endocrine systems. Stimulates the transmission of excitation in the synapses of the central nervous system, promotes neutralization and removal from the body, increases the body's resistance to hypoxia.

It is one of the components of myofibrils, participates in the synthesis of other amino acids, acetylcholine, ATP, urea, promotes the transfer and maintenance of the required concentration of potassium ions in the brain, serves as a link between the metabolism of carbohydrates and nucleic acids, and normalizes the content of glycolysis indicators in the blood and tissues. It has a hepatoprotective effect and inhibits the secretory function of the stomach.

Pharmacokinetics

Absorption is high. Penetrates well histohematic barriers(including through the BBB), cell membranes and membranes of subcellular formations. Accumulates in muscle and nervous tissues, liver and kidneys. Excreted by the kidneys - 4-7% unchanged.

Indications

Included complex therapy: (mainly minor seizures with equivalents), schizophrenia, psychoses (somatogenic, intoxicating, involutional), reactive depressive state, mental exhaustion, insomnia, consequences of meningitis and encephalitis, depression, progressive myopathy; impaired mental function of various etiologies, children's cerebral paralysis, consequences of intracranial birth trauma, polio (acute and recovery period), Down's disease; toxic neuropathy due to the use of isonicotinic acid hydrazides (including).

Contraindications

Feverish conditions, liver and/or renal failure, suppression of bone marrow hematopoiesis, anemia, increased excitability, violent mental reactions, peptic ulcer of the stomach and duodenum, nephrotic syndrome, obesity, increased sensitivity to glutamic acid.

Dosage

Adults - 1 g 2-3 times/day. Children under 1 year - 100 mg, up to 2 years - 150 mg, 3-4 years - 250 mg, 5-6 years - 40 mg, 7-9 years - 500 mg-1 g, 10 years and older - 1 g 2-3 times/day. For oligophrenia - 100-200 mg/kg for several months. Take orally 15-30 minutes before meals, if dyspeptic symptoms develop - during or after meals. The course of treatment is from 1-2 to 6-12 months.

Side effects

Maybe: vomiting, loose stools, central nervous system stimulation, allergic reactions, abdominal pain, nausea, increased excitability.

Amino acids are extremely important for our body. In total, today doctors identify many names of essential and non-essential amino acids that come with food. Today we are interested in glutamic acid. In bodybuilding this is one of the essential elements nutrition, which is responsible for the secretion of growth hormone, which is extremely important when gaining muscle mass. Today we want to take a closer look at this amazing amino acid and tell you how it is used around the world.

What it is

It has been known in bodybuilding for a long time. This is one of the elements that make up the proteins in our body. It is not essential; the body can replenish reserves from other amino acids that come from food. This is beef and eggs, beans and cottage cheese, so there will be sources of it on any table. However, glutamic acid in bodybuilding is additionally used in tablet form. Let's look at why athletes need it in increased quantities.

Why does the body need it?

It would be more accurately called L-glutamic acid. It has long been noted in bodybuilding that the better and faster a person’s metabolism is, the sooner the body will reach the standards it is waiting for. professional sports. And this amino acid is an active participant in all types of metabolism. Its effects are very diverse, it perfectly helps transmit signals along the nerves to the brain. It is formed from glutamine aminobutyric acid, which improves blood supply to the brain.

Increased need for protein

Who knows this more than professional athletes? During intensive weight gain, they have to absorb great amount protein foods, and additionally protein shakes. When they split, an incredibly toxic substance- ammonia. To prevent the body from being poisoned by it, under the influence of glutamine, ammonia is converted into urea, which is excreted naturally. Additionally, the amino acid helps stimulate the activity of the adrenal glands.

Great sport and body

Below we will look at how to take glutamic acid for bodybuilding. For now, let's dwell on what this will do for your body. Glutamine is a major component of muscle tissue. Without it, its formation, if possible, is far behind in terms of timing and intensity. And this is of great importance. Imagine a person doing his best in the gym month after month, but there are no results. What will happen? Motivation will decrease sharply, and perhaps he will quit classes altogether.

Why does glutamine play such an important role in this process? Glutamine’s ability to compensate for the lack of oxygen is also valuable for an athlete. The more intense physical exercise, the more your body will feel it. Thus, a simple amino acid, which is found in many foods, helps to quickly build muscle mass, as well as restore the body after exercise.

Reception features

It should be noted that even the most safe drug should not be taken without the recommendation of a doctor or fitness trainer. However, if you look at popularity, glutamic acid takes the leading position in bodybuilding. We’ll talk to you now about how to apply it. This amino acid is the most unstable in solutions. Therefore, if you plan to drink it immediately after training, then take it to the gym in powder form and consume it on the spot.

Dosage

But here everything is very individual. Obviously, it is important to consult a doctor before taking it. However we will tell you general schemes how glutamic acid is used in bodybuilding. The instructions recommend consuming from 8 to 20 g of glycogen per day. However, the dosage depends greatly on individual characteristics diets. Sometimes experienced bodybuilders increase this dose to 40 g per day, but this should be done gradually, monitoring the condition of your body.

Different dosage regimens

Since all athletes are different, the method of administration will also be different. Moreover, it may be difficult for an inexperienced bodybuilder to find the optimal scheme, so it is best to contact a professional trainer. However, our task is to tell you how glutamic acid is used in bodybuilding. Instructions for use recommend that beginners take a little at a time over 2 minutes. It is this method that ensures the most complete absorption by the muscles.

On days of increased sports load The body requires increased nutrition and oxygen supply. Therefore, it is recommended to take glutamine before entering gym and after training. It is usually recommended to take 5-20 g at a time for the drug to have the greatest effect.

It is very important to take amino acids big amount liquids. Experienced trainers recommend taking it with a protein shake or simply with food. But you shouldn’t mix it with other amino acids; you need at least a temporary break.

Increased dosage

If an athlete decides to dry out his body and at the same time gain muscle mass, then it is necessary to change the dosage. Typically, a low-carbohydrate diet is followed during this period. Therefore, the trainer prescribes a minimum of 30 g of glutamine per day to avoid muscle catabolism. That is, if the body does not have enough carbohydrates, it will begin to suck amino acids from your muscles. No growth or strengthening is possible in this case. One more interesting fact should be noted. Daily intake glutamine in an amount of 20-40 g allows you to activate immune system. Doctors established this using the example of patients who received transplants. Bone marrow. And for athletes high loads good immunity it will come in handy.

Judging by the reviews of experienced athletes, taking this amino acid in correct dosage helps to significantly increase the capabilities of your body and quickly achieve your goals. As an experiment, a training cycle was carried out more than once, pre-agreed in time. At the same time, several people pumped as usual, while others took glutamic acid. As a result, it was obvious that in the second case all indicators were significantly ahead. In addition, athletes demonstrate increased performance and good health.