Vikasol instructions for use in tablets. These include such negative factors as

Instructions for use:

Vikasol belongs to the group of vitamins obtained synthetically. Vitamin K analog.

pharmachologic effect

Water soluble analog natural vitamin K obtained in the laboratory. Takes part in the formation of prothrombin. Normalizes blood coagulability. Vitamin K deficiency leads to increased bleeding.

Release form

Vikasol is produced in powder, in tablets of 0.015 g and in ampoules of 1 ml with a 1% solution.

Indications for Vikasol's use

The use of Vikasol is advisable in the following cases:

Jaundice, which develops due to untimely entry of bile into the intestine;

Capillary and parenchymal bleeding;

Bleeding that occurs with peptic ulcer stomach and duodenum;

thrombocytopenic purpura;

Radiation sickness;

Persistent nose and hemorrhoidal bleeding.

According to the instructions, Vikasol is prescribed to pregnant women in the last trimester to prevent bleeding in newborns.

It is possible to use Vikasol in newborns with hemorrhagic disease (increased bleeding).

Vikasol injections and tablets are prescribed for juvenile uterine and dysfunctional uterine bleeding before puberty and in the premenopausal period.

The use of Vikasol is advisable in case of bleeding in tuberculosis, septic diseases, reduced clotting, the use of anticoagulants, vitamin K antagonists, phenylin, neodicoumarin and other drugs with a similar effect.

The appointment of a solution for injection and Vikasol tablets for hemophilia and Werlhof's disease does not bring the desired therapeutic effect.

Instructions for use Vikasol and doses

Vikasol tablets are taken orally. The solution for injection is prescribed intramuscularly. The average dose for adults: Vikasol tablets from 0.015 to 0.3 g per day; solution for injection from 0.01 to 0.015 g. Maximum allowable doses for adults: Vikasol tablets at a time, not more than 0.03 g, per day - not more than 0.06 g; intramuscularly in injections of not more than 0.015 g per injection and not more than 0.03 g per day.

It is possible to use Vikasol for children under one year old. In this case, the allowed daily dose ranges from 0.002 to 0.005 g. Children under three years of age can take Vikasol at a dose of 0.006 grams, at the age of 3 to 4 years - 0.008 g, at 5-9 years old you can prescribe 0.01 g of Vikasol, from 10 to 14 years 0.015 g. The daily dose is divided into 2 or three doses, Vikasol is taken according to the instructions for three or four days in a row, then a four-day break is taken, and the course is repeated again.

The dose of Vikasol for newborns should not exceed 0.004 grams.

Women in labor are prescribed Vikasol in a daily dose for adults at one time, if childbirth does not occur, then the use of Vikasol is advisable after 12 and 24 hours.

Side effects

The instructions for Vikasol indicate possible side effects. These include:

Hypervitaminosis of vitamin K, resulting in an increase in prothrombin and thrombin, bilirubin;

Toxicosis in children, which manifests itself in the form of seizures.

Contraindications to the use of Vikasol

Vikasol is contraindicated in patients with increased blood clotting and thromboembolism (blockage of blood vessels by blood clots).

Vikasol during menstruation

Vikasol during menstruation has the ability to reduce the amount of discharge, if they are abundant. But Vikasol during menstruation does not always bring the desired effect. Therefore, it is not recommended to take Vikasol during menstruation on your own, it is necessary to be examined by a gynecologist. It should be remembered that only a doctor can prescribe Vikasol.

The release form of Vikasol is tablets and ampoules for solution. The number of indications for the use of this tool is quite large. For example, these injections are prescribed for hemorrhagic syndrome, hypovitaminosis, bleeding, uterine bleeding. Concerning pharmacological action, then participates in the formation of prothrombin.

Indications for use

All indications indicated in the instructions are listed below:

• hemorrhagic syndrome, which is associated with hypoprothrombinemia;
• bleeding after injuries, wounds, surgical interventions;
• hemorrhagic disease newborns;
• overdose of vitamin K antagonists;
• hypovitaminosis K;
• with dysfunctional uterine bleeding.

Contraindications for use

In the instructions for tablets and ampoules, not only indications are recorded, but also contraindications. There are three in total: hypersensitivity to the components hemolytic disease newborns, increased blood clotting. It should be taken with caution according to the prescription during pregnancy and insufficiency in the liver.

Vikasol instructions for use - dosage in tablets and ampoules

Both tablets and ampoules for adults should be taken in the amount of 15-30 mg per day. Tablets are taken orally, and ampoules - intramuscularly. For newborns, the dosage should not exceed 4 mg. For older children, the amount of ml that can be taken according to the instructions is also less than for adults.

Vikasol instructions for menstruation for use

Reception during menstruation should be carried out carefully. The main purpose for tablets and ampoules at this time is to stop menstruation. In order to stop menstruation, two tablets should be taken per day. As for the ampoules, menstruation can be stopped with one injection of Vikasol.

Vikasol instructions for use in uterine bleeding

The description of the indications indicates that in addition to menstruation, it can be used for uterine bleeding. For intramuscular injection the dosage is 15 mg. The injections are given twice a day.

Vikasol for newborns

In the information from the reviews, it can be concluded that this remedy and its analogues are widespread even for newborns. The permissible daily dose is about 0.002 - 0.004 g. At the same time, it can be prescribed even to women in labor.

Vikasol injections instructions for use

Intramuscular injections with a 1% solution should be 0.015 g per injection and 0.03 g per day maximum. However, injections in such doses can be prescribed for jaundice due to non-receipt of bile into the intestines, for menstruation and for other indications in the instructions for adults only. For children, the dosage is much less.

Vikasol and alcohol compatibility

This remedy is one of many that are compatible with alcohol. Since this drug is an analogue of Vitamin K, it can be very useful for people who abuse alcohol.

During early pregnancy Vikasol

As for pregnancy, the remedy is more often prescribed in the last trimester in order to prevent bleeding. However, in medical practice there are enough cases when it is used for the same purpose in the first trimester.

Analogues

Bleeding during menstruation and other cases can be stopped by analogues such as Dicinon and Etamzilat. Takhakomb and Traneksam are also considered analogues.

Vikasol or Dicinon which is better?

Dicinon outperforms Vikasol in terms of speed. For other indicators (decrease pain and removal of profusion), these drugs are generally equal. This is confirmed by the reviews of doctors. At the same time, Vikasol is much cheaper.

Menadione sodium bisulfite (menadione)

Composition and form of release of the drug

30 pcs. - jars of dark glass (1) - packs of cardboard.
10 pieces. - cellular contour packings (3) - packs of cardboard.

pharmachologic effect

Antihemorrhagic agent. It is a synthetic analog of K. It is a cofactor in the synthesis of prothrombin and other blood coagulation factors (VII, IX, X) in the liver, and contributes to the normalization of the blood coagulation process.

Pharmacokinetics

After oral administration, it is absorbed from the gastrointestinal tract. Protein binding is reversible. Accumulates mainly in the liver, spleen, myocardium. It is converted into vitamin K 2 in the body. The process of transformation occurs most intensively in the myocardium, skeletal muscles, somewhat weaker - in the kidneys.

Metabolites of vitamin K (monosulfate, phosphate and diglucuronide-2-methyl-1.4-naphthoquinone) are excreted in the urine - up to 70%.

Indications

Hemorrhagic syndrome associated with hypoprothrombinemia; hypovitaminosis K (including with obstructive jaundice, hepatitis, prolonged diarrhea); hemorrhagic disease of the newborn; bleeding after injuries, injuries and surgical interventions; in gynecology with complex treatment dysfunctional uterine bleeding unrelated to organic pathology, with menorrhagia. As a specific antagonist for bleeding associated with taking indirect drugs. III trimester of pregnancy (to prevent bleeding in newborns).

Contraindications

Increased blood clotting, thromboembolism, hypersensitivity to menadione.

Dosage

Adults when taken orally - 15-30 mg / day, intramuscularly - 10-15 mg / day.

Children under the age of 1 year - 2-5 mg / day, up to 2 years - 6 mg / day, 3-4 years - 8 mg / day, 5-9 years - 10 mg / day, 10-14 years - 15 mg / day The frequency of admission is 2-3 times / day. The duration of treatment is set individually.

Maximum doses: for adults by ingestion single dose- 30 mg, daily - 60 mg; with i / m administration, a single dose - 15 mg, daily - 30 mg. For newborns - 4 mg / day.

Side effects

Allergic reactions:, itching, erythema, urticaria, bronchospasm.

Violations menstrual cycle- one of common causes women's visits to a gynecologist. This pathology may manifest different symptoms. However, the biggest concern is heavy periods, which can cause a number of complications. "Vikasol" increases the coagulation characteristics of the blood, is able to reduce the amount of bleeding and reduce the number of "critical" days.

The main active ingredient in Vikasol is sodium menadione bisulfite. This medicine belongs to the group of antihemorrhagic drugs and is similar in structure to vitamin K. The latter is extremely important substance, contributing to the formation of blood coagulation factors: VII, IX, X. The presence of these factors is necessary to start the mechanism of fibrin clot formation. Vitamin K is involved in the conversion of prothrombin to thrombin, which affects the duration of bleeding.

"Vikasol" can not be used to deliberately provoke a delay in menstruation. The drug does not change hormonal background and can not affect the onset of menstruation.

Release form

Vikasol is produced in the form of two pharmaceutical forms.

1. Pills. Contain 0.015 g menadione sodium bisulfite. In addition, this dosage form includes fillers: sucrose, starch, calcium stearate and others.
2. Ampoules. Injections contain 1 ml of a solution containing 0.01 g of menadione. This form release is intended only for intramuscular injection.

Within the space of active substance medication is in bound state with plasma proteins. "Vikasol" penetrates well into almost all tissues of the body, especially its high concentrations are found in the heart muscle, striated muscles, spleen, liver. Most of this drug is excreted in the urine.

After ingestion of the tablet form of the drug, it is rapidly absorbed into gastrointestinal tract. Menadione acts as early as eight hours after entering the bloodstream.

Indications

Indications for the use of "Vikasol" are any conditions associated with increased risk bleeding. Most often, the drug is recommended for the following pathologies:

• hemorrhages caused by insufficient intake of vitamin K in the body (with intestinal diseases, severe pathologies liver);
• hemorrhagic diseases in newborns;
• bleeding caused by trauma or injury;
• uterine bleeding against the background of a disturbed menstrual cycle;
• heavy periods with fibroids or the onset of menopause;
• high risk bleeding while taking anticoagulants;
• nosebleeds;
• bleeding from the gastrointestinal tract;
• bleeding with hemorrhoids.

Also "Vikasol" is prescribed for the prevention of bleeding in preoperative period or after the operation.

On the Internet there are recommendations on the use of menadione in veterinary medicine. In particular, to save animals in case of poisoning rat poison(inhibits vitamin K). However, the drug does not compensate for the resulting deficiency of vitamin K, the method itself has no scientific evidence, and it is better to use special preparations for pets.

Dosages

Tablets are taken between meals with a glass of enough drinking water. children infancy the drug is administered parenterally.
The dosage of the drug is determined according to the following table.

Table - Vikasol dosage by age

The maximum amount of medicine that an adult patient can take at one time is 30 mg. Per day, no more than 60 mg of Vikasol is allowed, which are divided into two or three doses. (Newborns - no more than 4 mg).

In the treatment of heavy periods, the drug is taken a few days before the expected date of menstruation. Total time therapy - three to four days.

It is not recommended to take the drug without consulting a gynecologist. Abundant periods can be caused by organic pathology in the uterus or hormonal disorders. In this case, "Vikasol" will only reduce the symptoms, but will not eliminate the problem.

Side effects

In general, the drug is well tolerated by patients, but the following are sometimes noted: side effects:

• disorders in the blood system (anemia of the hemolytic type, hemolysis in the presence of congenital fermentopathy);
• allergy in the form skin rash, itching, peeling, spasm of bronchioles;
• vestibular disorders, weakness, taste disturbances;
• increased levels of bilirubin;
• drop in blood pressure;
• cardiopalmus.

Extremely rare when taken large doses"Vikasola" may cause an overdose. It manifests itself with the following symptoms:

• increase in prothrombin index;
• increase in the level of bilirubin in the blood;
• convulsions.

Contraindications

The appointment of "Vikasol" is contraindicated in the following cases:

• individual intolerance individual components drug;
• increased blood clotting;
• tendency to thrombosis;
• violation of sugar metabolism;
• severe liver dysfunction.

Tablets are not recommended for children under three years of age. They should be used with caution in pregnant and lactating women. If the patient is diagnosed with diseases that lead to impaired outflow through the biliary tract, then only the injection form of the drug should be used.

Caution should be exercised if the following medications are already prescribed along with Vikasol:

• indirect anticoagulants;
• antibiotics a wide range actions;
• quinidine;
• salicylates;
• quinine;
• sulfonamides;
• cholestyramine;
• sucralfate.

"Vikasol" refers to over-the-counter drugs. Its exact analogues on pharmaceutical market not presented. But as an alternative, the pharmacist can offer other drugs that have a hemostatic effect: "Etamsilat" ("Dicinon") or "Tranexam" (tranexamic acid).

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The price of Vikasol tablets (15 mg, 20 pcs.): 60-90 rubles.

Vikasol during pregnancy

Pregnancy is a very significant moment in a woman's life, but this exciting and touching period does not always go smoothly. The most common threat of spontaneous miscarriage is vaginal bleeding. The drug Vikasol in such cases helps to reduce blood loss and maintain pregnancy.

Threat factors for miscarriage

The appearance of the smearers spotting from the vagina during pregnancy can cause a number of reasons.

This includes such negative factors How:

• ectopic pregnancy (when a fertilized egg is attached and develops not in the uterus itself, but outside it);
• non-developing pregnancy and embryonic death due to genetic abnormalities;
• failures in hormonal sphere in a pregnant woman;
• abnormal localization gestational sac in the uterine cavity.

Cause vaginal bleeding can also become:

• small interval between births;
• diseases reproductive organs women;
• transferred diseases of a viral nature;
• premature detachment of the placenta;
• physical exercise.

Vikasol during early pregnancy

The initial signs of threatened miscarriage often appear on the early dates in the form of spotting vaginal discharge, which is why future mom must pay special attention to changes in your body.

In this situation, Vikasol can be prescribed by a gynecologist to maintain and harmonious development of pregnancy, and psychological calmness and, if possible, complete absence physical activity. This drug is a powerful hemostatic agent, so doctors can recommend it only on a personal basis after evaluating the results of the analysis on the coagulogram (blood clotting process). For the most effective result Vikasol is used as an injection.

Pharmacological actions of Vikasol

Vikasol is a medicine that is a vitamin synthetic origin with properties similar to vitamin K. This preparation contains active substances that help prevent bleeding. The drug supports the synthesis of prothrombin and helps normalize blood clotting.

Features of the use of the drug

It should be remembered that only a doctor can accurately determine the cause of spotting spotting and prevent complications in time. Therefore, a pregnant woman should in no case self-medicate and try to stop the bleeding on her own.

When using the drug, the effect active substance begins only 12 hours after ingestion. Vikasol accumulates in the body and is converted into vitamin K. The great advantage of the drug is that it does not adversely affect the course of pregnancy and does not harm the fetus. Vikasol is often used in combination with No-Shpa and vitamin E. No-Shpa is the best antispasmodic, and vitamin E is a monopreparation that has a number of properties that contribute to the harmonious development of pregnancy.

Proper use of the hemostatic agent Vikasol

Vikasol is available in the form of tablets and solution for injection in ampoules. In tablet form, the daily dose of the drug should not exceed two tablets with an interval of 12 hours for 3-4 days. Next, you need to take a break with the subsequent continuation of the course of therapy. The drug in the form of tablets is convenient for treatment not only in a stationary mode, but also at home. Special attention it is worth paying attention to the fact that Vikasol is contraindicated in people with increased clotting blood and with a high risk of thromboembolism (blockage of blood vessels by blood clots).

To prevent uterine bleeding, which may occur on initial stage labor activity in women, Vikasol may be prescribed by a doctor during the first contractions.

Prevention during pregnancy

Usually, the largest number miscarriages occur in the first trimester of pregnancy. If we are talking about spontaneous abortion in the early stages of pregnancy, then in such cases there are often chromosomal abnormalities fetus. To stop uterine bleeding doctors prescribe the use of Vikasol and other medicines aimed at maintaining the integrity of the walls of blood vessels, as well as preventing and stopping bleeding. Uncontrolled and long-term use drug. The medication should only be taken under medical supervision. In most cases, two days are enough for physicians to evaluate the effectiveness of the application.

Contraindications

Contraindications to the use of Vikasol are:

• blood hypercoagulability;
• thromboembolism;
• liver disease;
• hypersensitivity to the components of the drug.

Therefore, taking the medicine personally, without a prescription from a specialist, is strictly prohibited.