9 days after artificial insemination, acne appeared. Results and sensations after artificial insemination

For all those interested, artificial intrauterine insemination - this is the “infusion” of the husband’s (or donor’s) sperm into the woman’s uterus. For this procedure, a thin catheter is used, and the whole process lasts no more than two to three minutes. Everything is simple, easy and quite painless, although the moment of penetration of the catheter into the cervical canal is quite unpleasant, although it only lasts seconds. The only problem AI is its low efficiency.

I “went” to AI twice and, alas, without success. More precisely, it worked the first time (Hurray! Beginners are lucky!), the hCG began to rise, but at 5.5 weeks the pregnancy spontaneously terminated. The second attempt was a complete failure.

However, the very fact of the miracle that happened suggests that AI is not at all useless, and someone was actually lucky enough to get pregnant in this way. That is why I wrote material about how it goes, how much it costs, and how artificial insemination usually ends.

How is insemination carried out?

Preparation for insemination takes about a month: this is not the case when you come, pay money and have a quick “infusion”. Be prepared for the fact that you will have to visit a therapist, endocrinologist, mammologist, and even have a heart ultrasound before you are allowed to sign an agreement for the provision of services. When everything additional research will be passed, most likely the fertility specialist will prescribe an ovulation stimulation regimen. Of course, there is AI in natural cycle, but much less frequently: in this procedure, the very fact of accomplished ovulation, confirmed by ultrasound, is extremely important.

So, after the ultrasound shows the leading follicle ready for ovulation, you will be assigned days for AI. Most likely, the procedure will be performed twice - before and after ovulation. Although some clinics make do with a one-time “infusion”.

On day “X,” the spouse must arrive at the clinic two to three hours earlier than the time scheduled for AI and donate sperm - it will be processed in a centrifuge so that only the best motile sperm remain. It is worth mentioning here that in the end there will be very little sperm left, but the quantity, as we already know, does not mean anything - the main thing is the quality characteristics.

When you arrive at the clinic, the first thing you will do is change into a hospital gown and cap. Don’t be alarmed, a twenty-minute stay in the ward will not threaten you with anything terrible.

The procedure itself will take place in the operating room (if you have already undergone laparoscopy, you will immediately recognize in the operating room the wonderful Rakhmanov bed on which you will one day give birth to your child). As mentioned, the AI lasts a couple of minutes. Then you will be left to lie down for about half an hour - and then go home. All.

Feelings after insemination by day.

For some reason, it is assumed that after the “infusion” the woman will feel somehow special. However, it is not. The first day there may be a nagging pain in the abdomen, but soon it goes away, and after 48-72 hours there is absolutely no sensation. (In my first insemination, the nagging pain returned a week after AI and ended only when the pregnancy was terminated. In the second case, the pain also appeared after about 7 days, but disappeared by the beginning of menstruation.)

Since in the second phase support with utrogestan is most often prescribed, unpleasant chest pain and a feeling of heaviness may occur - but this, alas, does not yet mean pregnancy. As well as the presence nagging pain before the expected menstruation does not mean failure.

And, of course, finally about the most exciting thing - pregnancy tests. You can find a lot of advice on the Internet about when to start “soaking” the treasured tests, but I think my example will very clearly illustrate the real situation: I did the first test after receiving the hCG result (32), there was not even a “ghost” on the “super-ultra-hypersensitive” test " The second strip appeared only on the 29th day of the cycle (hCG 59). Everyone's body is structured differently. AND late implantation far from a myth, keep that in mind.

How much does insemination cost in Moscow?

The cost ranges from 8 to 30 thousand rubles - such an obvious difference is due to the fact that the insemination protocol is specifically included in the price. Minimum price means that you will pay for all additional visits to your doctor and ultrasound monitoring separately. Experience shows that the total amount in this case is much higher than in clinics where “all inclusive”. In addition, if AI is carried out in an induced cycle (i.e. ovulation is stimulated with drugs), you will have to pay for the drugs separately, and this is another 600 to 15 thousand rubles. And, of course, don’t forget to add to this amount the list necessary examinations before the procedure.

In total, both inseminations cost me approximately 85 thousand rubles.

How effective is insemination?

If you believe official statistics 2014, insemination guarantees only 11% success. Yes, this is disproportionately small compared to IVF. But AI is a more gentle procedure, and, importantly, more economical, so it’s up to you to decide. After two unsuccessful attempts, I refused to continue, but the first attempt still brought results, and if you are just preparing for the AI procedure, let this thought warm you.

For couples facing infertility, assisted reproductive technologies become a chance to become parents.

One of the simplest and available methods assisted reproduction is artificial insemination. What is the essence of the procedure? How to behave after insemination? Who is it indicated for and are there high chances of pregnancy?

Artificial insemination - what is it?

Artificial insemination can rightfully be considered one of the first scientific methods assisted reproduction. At the end of the 18th century, the Italian doctor Lazaro Spalazzi first tested it on a dog, resulting in healthy offspring of three puppies.

Six years later, in 1790, artificial insemination (AI) was first tested on humans: in Scotland, Dr. John Hunter inseminated a patient with the sperm of her husband, who suffered from an abnormal penis structure. Today the procedure is widely used throughout the world.

Artificial (intrauterine) insemination is a technology that involves the introduction of male sperm into the cervical canal or uterus of a woman. For this, a catheter and syringe are used. The day for AI is calculated taking into account the patient’s menstrual cycle.

It is necessary to accurately determine the periovulatory period, otherwise the procedure will be useless. Technology is used as in natural menstrual cycle, and in hormonally stimulated.

Sperm is obtained outside of sexual intercourse in advance (and then frozen, thawing on the day of AI) or several hours before the procedure. It can be processed or introduced unchanged.

How effective is artificial insemination? The statistical results are not very promising: fertilization occurs in only 12% of cases.

Who is the procedure indicated for?

For women, indications for vaginal insemination are:

the desire to become pregnant “for oneself” without having a sexual partner;
infertility caused by cervical factors (cervical pathologies);
Vaginismus.

Indications for insemination on the part of men are as follows:

infertility;
disorders of an ejaculatory-sexual nature;
unfavorable prognosis for genetic diseases transmitted by inheritance;
sperm subfertility.

In the first three cases, donor sperm is used.

After the procedure: how does the woman feel?

In order to undergo intrauterine insemination, a woman does not need to go to the hospital at all. The procedure is performed on an outpatient basis and lasts only a few minutes.

How does the patient feel? In practice, she experiences sensations that are no different from those during normal gynecological examination. A speculum is inserted into the vagina, and perhaps the most unpleasant experience is associated with this. Almost immediately after artificial insemination they pass.

For a short time, there may be a painful pulling sensation in the lower abdomen, which is caused by irritation of the uterus. IN in rare cases available anaphylactic shock when introducing unpurified seminal fluid.

To avoid allergic reactions and to improve the quality of sperm, it is recommended to clean it, even if the seed of the patient’s spouse is used as a biomaterial.

How to behave after completion of the procedure?

The gynecologist performing the procedure will definitely tell you how to behave after insemination and warn about possible consequences, will give necessary recommendations. Immediately after the injection of sperm, the woman will need to remain in a supine position for one and a half to two hours.

A small pillow should be placed under the buttocks - an elevated pelvis facilitates better advancement of injected sperm into the fallopian tubes. This increases the chance of conception, for which, in fact, artificial insemination was carried out.

The success rate of the procedure depends on the patient’s age, her condition reproductive health, the quality of the sperm used. To improve AI efficiency donor material undergoes processing, as a result of which only the highest quality sperm remain.

So that a potentially fertilized egg can fully develop and implantation of the fertilized egg is successful, it is prescribed hormone therapy progesterone. If three cycles in a row after artificial insemination do not conceive, other methods of assisted reproduction are selected.

What can and cannot be done during insemination?

Fertilization does not occur immediately at the moment of sperm injection; it requires several hours, up to a day, after insemination. What to do to increase the chance of pregnancy?

On the first day you must refuse:

from taking a bath, as water helps wash out some of the sperm from the vagina;
from douching;
from the administration of vaginal medications.

But having sex is not on the list of things that should not be done after insemination; some experts even see a benefit in this: unprotected sexual contact promotes better movement of injected sperm into the tubes.

Conclusion

By following these recommendations after insemination, within a week (that’s how long it takes for a fertilized egg to move into the uterine cavity and attach there) you can conduct a blood test for hCG. This hormone is a marker of pregnancy; it begins to be produced immediately after implantation of the fertilized egg into the uterus. A home express diagnostic method - a pregnancy test - is not advisable to use earlier than 12-14 days. In urine, the concentration of hCG is achieved somewhat later than in the blood.

Video: Intrauterine insemination (IUI)

All large quantity married couples in last years need assisted reproductive technologies. Just a few decades ago, despite certain problems, women and men remained childless. Nowadays medicine is developing at a very fast pace. So if you can't for a long time If you want to get pregnant, you should use a method such as insemination. For those who succeeded the first time, this article will tell you. You will learn about the procedure and how it is carried out, and you will also be able to read reviews from patients who have gone through this stage.

Assisted intrauterine insemination

Artificial insemination is the process of insertion into the cavity reproductive organ woman's sperm from her partner. This moment- the only thing that happens artificially. After this, all processes are carried out naturally.

Insemination can be performed with the sperm of the husband or a donor. The material is taken fresh or frozen. Modern medicine and the experience of doctors allow a couple to conceive a child even in the most seemingly hopeless situations.

Indications for surgery

The insemination procedure is indicated for couples who cannot conceive a child on their own within a year, and both partners do not have any pathologies. Usually in this case they talk about infertility unknown origin. Also, indications for insemination will be the following situations:

decreased sperm quality or sperm motility in a man;
erectile dysfunction;
irregular sex life or sexual disorders;
cervical factor of infertility (production of antisperm cells in cervical canal partners);
age factor (both men and women);
anatomical features of the structure of the genital organs;
impossibility of sexual intercourse without protection (in case of HIV infection in a woman);
the desire to conceive a child without a husband, and so on.

Insemination with sperm is usually carried out in private clinics providing auxiliary reproductive technologies. The procedure requires some preparation and has several stages. Let's look at them.

Exploratory survey

Artificial insemination involves diagnosing both partners. A man must have a spermogram so that specialists can sensibly assess the condition of the sperm. If unsatisfactory results are obtained during the procedure, additional manipulations will be applied. The partner is also examined for the presence of sexually transmitted infections, undergoes a blood test and fluorography.

The woman has to extensive diagnostics than that of a man. The patient undergoes ultrasound diagnostics, tests to determine genital tract infections, and provides fluorography. Also to the expectant mother needs to be researched hormonal background, determine the ovular reserve. Depending on the results obtained, further tactics for working with the couple are chosen.

Initial stage: stimulation or natural cycle?

Before insemination, some women are prescribed hormonal drugs. They must be taken in a strictly prescribed dose.

The doctor designates the days when the medicine is administered. It can be in the form of tablets or injections. Hormonal stimulation of the ovaries is needed for a woman with ovulation disorders, as well as for those patients who have a decreased number of eggs. individual feature or as a consequence of ovarian resections. Also, a decrease in ovarian reserve is observed in women approaching 40 years of age.

Both during stimulation and in the natural cycle, the patient is prescribed folliculometry. A woman regularly visits a specialist ultrasound diagnostics, which measures follicles. Attention is also paid to the condition of the endometrium. If slime layer grows poorly, the patient is prescribed additional medications.

Important point

When it is discovered that the follicle has reached the appropriate size, it is time to act. Depending on when ovulation occurs, insemination is scheduled a few days in advance or a couple of hours later. Much depends on the condition of the sperm. If fresh material is used, its administration can occur no more than once every 3-5 days. Therefore, the couple is offered two options:

insemination 3 days before ovulation and a few hours after it;
injection of the material once directly at the time of follicle rupture.

Which method is better and more effective has not yet been determined. Much depends on the health of the partners and the indications for which insemination is performed. Those who succeed the first time with a single injection are not advised to decide on a double injection. And vice versa. The situation is different with frozen sperm or donor material.

Another variant

Insemination by a donor always involves preliminary freezing of the material. Such sperm, after thawing, can be injected in several portions. Efficiency this method slightly higher than fertilization with fresh material.

You can also freeze sperm for your partner married couple. You don't have to become a donor to do this. You need to discuss this issue with a reproductive specialist. Over time, its quality improves, only the best, fastest and healthy sperm. Pathological cells are removed from the material. As a result of manipulation, a so-called concentrate is obtained.

Material introduction process

This procedure takes no more than half an hour. The woman sits in her usual position. A thin catheter is inserted into the cervical canal through the vagina. At the other end of the tube a syringe with collected material. The contents of the injection are delivered to the uterus. After this, the catheter is removed, and the patient is advised to lie down for another 15 minutes.

On the day of insemination, a woman is prohibited from straining and lifting heavy objects. Rest is recommended. There are no restrictions on the mode for the next day. However, you need to maintain personal hygiene, since after insemination there is a risk of infection.

On the first and second days from the transfer of material, a woman may experience a pulling sensation. painful sensations in the lower abdomen. Doctors do not advise taking medications. If the pain seems unbearable to you, then you need to seek help. medical care. Also, some patients may have minor bloody issues. They are associated with minor and possible trauma to the mucous membrane. The discharge goes away on its own and does not require the use of additional medications.

Diagnosis of pregnancy

After insemination is performed, pregnancy should occur within a few hours. After this time, the egg becomes incapacitated. But at this moment the woman still has no way of knowing about her new position. Some patients are prescribed hormonal support. Drugs are always needed in a cycle with stimulation and sometimes in a natural one.

The test after insemination will show correct result after 10-14 days. If a woman was stimulated and given an injection human chorionic gonadotropin, That positive test she can see immediately after the procedure. However, he does not talk about pregnancy. The reagent on the strip only shows the presence of hCG in the body.

Ultrasound can most accurately confirm or refute pregnancy. But this may not be earlier than 3-4 weeks after the procedure. Some modern devices allow you to get results within 2 weeks.

Insemination: who got it right the first time?

There are statistics of couples who performed such manipulation. The chance of pregnancy ranges from 2 to 30 percent. Whereas in the natural cycle, without auxiliary reproductive methods, in healthy spouses it is 60%.

A favorable outcome on the first try usually occurs under the following conditions:

the age of both partners is in the range from 20 to 30 years;
the woman does not have any hormonal diseases;
the man and woman have no history of genital tract infections;
partners lead healthy image life and prefer proper nutrition;
the duration of unsuccessful attempts to conceive a child is less than five years;
no previous ovarian stimulation or gynecological surgery had been performed.

Despite these parameters, success can be achieved in other cases.

The statistics are disappointing - every year the number infertile couples is only increasing, and how many of them want children! Thanks to the latest technologies and progressive treatment methods, babies are born, even though it would seem that this is impossible. Artificial insemination is a procedure that allows a woman diagnosed with infertility to become a mother using donor sperm. What is the essence of the technology, to whom it is contraindicated and how great are the chances of having a child - more on this later.

What is artificial insemination

As one of the methods of artificial insemination, insemination helps parents find their long-awaited child. The procedure significantly increases the likelihood of conception, since it is preceded by a careful selection of material for the operation. Among the sperm, the most active ones are selected, and the weak ones are removed. The protein components of the ejaculate are removed because they can be perceived by the female body as foreign.

Intrauterine insemination is not a panacea for infertility, but only one way to get pregnant artificially. According to research positive effect is estimated at a maximum of 30–40 percent. A single session does not guarantee the development of pregnancy, so the operation is performed up to 3 times per monthly cycle. If conception does not occur after several procedures, it is recommended to turn to other methods of artificial insemination. Pregnancy itself with intrauterine insemination is no different from normal.

Why is artificial insemination possible?

It would seem why women cannot get pregnant, but with the artificial introduction of ejaculate, fertilization occurs. One of the features lies in the female body. The point is that in cervical mucus antibodies are produced to male sperm. It turns out that it simply kills sperm, and does not facilitate their penetration into the egg. The procedure helps deliver the treated material directly to the uterus, bypassing the cervical canal. In this way, even with low sperm motility, the chance of getting pregnant increases.

Indications

As can be seen from the above, the main indication for artificial intrauterine insemination is the immunological incompatibility of partners. In fact, individual reasons, for which the procedure is resorted to much more often, so it is worth considering them in more detail. The main problems for women are considered to be inflammatory processes in the cervical canal. The disease prevents sperm from passing into the uterus, preventing a woman from becoming pregnant.

Artificial insemination is used for vaginismus, a problem where sexual intercourse is not possible due to spasms and pain. Injuries and pathologies of the reproductive organ that interfere with getting pregnant, abnormalities in the position of the uterus, infertility of an unclear nest, surgical interventions on the cervix - another of the many reasons to contact the clinic for an insemination procedure.

Until recently, the cause of female infertility was sought only in the weaker sex, but, as studies have shown, men's problems are often dominant in this matter. Low motility and a small number of sperm that find it difficult to reach the end point, and azoospermia are some of the main diseases due to which artificial insemination is prescribed if previous treatment does not produce any results. Disorders with potency and ejaculation can also be an indication for the procedure.

Genetic diseases, as a result of which there is a possible risk of having a sick baby or with psychophysical characteristics of the baby, is another reason why artificial insemination is prescribed. True, then the procedure is carried out with the donor’s sperm, to which the husband (and the future official father) gives written consent. Fertilization with seminal fluid from the clinic’s database is also carried out for single women who want to become pregnant.

Advantages

Intrauterine insemination is the first method that is used for problems with conception. The main advantage is the absence great harm female body. It is possible to carry out artificial insemination even if the exact reason infertility. The procedure does not require lengthy preparation, and its implementation does not take much time. The most important trump card of use this method is its low cost.

Preparation

Like any operation, but intrauterine insemination medically is such, the procedure requires preparation. Just the desire to do artificial insemination is not enough; you need to come to an appointment with a doctor, who will prescribe an action plan after drawing up a family history and a thorough analysis of the situation during a conversation. Then it is necessary to sign certain papers confirming the consent of the spouses to carry out the conception. If it is necessary to use donor sperm, the number of documents for approval increases significantly.

Tests before insemination

Previously, to determine whether the couple is prepared for the artificial insemination procedure, the following tests are taken from the couple:

HIV AIDS);
stick infections;
hepatitis;
passive hemagglutination reaction (RPHA).

After a 3-5 day period of abstinence, the man takes a spermogram, which determines sperm motility. Women will have their patency checked fallopian tubes, using hysterosalpingography, the uterus is examined. Ultrasound detects the presence of ovulation. If there are problems, hormones are used to stimulate egg production. The microflora is cultured to determine the presence of papillomavirus, ureplasma, group B streptococcus, which can cause the impossibility of bearing a fetus.

Sperm preparation

Immediately before the insemination procedure artificially The seminal fluid is donated, after which it is examined and processed. There are 2 ways to prepare cells: centrifuge processing and flotation. The first option is preferable, since this increases the chances of conception. Sperm preparation involves removing acrosin from it, a substance that inhibits sperm motility. To do this, portions are poured into cups and left to liquefy, and after 2-3 hours they are activated special drugs or passed through a centrifuge.

On what day is insemination done?

According to doctors specializing in these issues of gynecology, the best option To carry out artificial insemination is the introduction of sperm into the uterus three times:

1-2 days before ovulation;
On the day of ovulation;
After 1-2 days, if there are several maturing follicles.

How does the procedure work?

Artificial insemination can be carried out independently or directly with the participation of a specialist in the clinic. To do this, the woman is placed on gynecological chair, with the help of a mirror, access to the cervix is opened. The doctor inserts a catheter, and biological material is drawn into a syringe connected to it. Then there is a gradual introduction of sperm into the uterine cavity. After insemination, the woman should remain motionless for about 30-40 minutes.

Insemination with donor sperm

When identifying serious illnesses the woman's partner, such as hepatitis, HIV and other potentially dangerous diseases, including genetic ones, then the donor’s sperm is used, which is stored frozen at a temperature of -197°C. Information about a person is not declassified, but the wife can always bring with her a person who has the right to surrender seminal fluid for subsequent artificial insemination of the patient.

Husband's sperm

When using biological material from a spouse, sperm collection occurs on the day of the insemination procedure. To do this, the spouses come to the clinic, where biological material is donated. After this, the semen is analyzed and prepared for use. It is important to understand that before donating sperm, a man must abstain from sexual intercourse for at least 3 days in order to improve the quality of sperm.

Artificial insemination at home

Artificial insemination at home is allowed, although according to doctors its effectiveness is considered minimal, however, judging by the reviews, successful attempts have been recorded. You can buy it at the pharmacy special set for carrying out manipulations at home. The algorithm differs from that carried out in the clinic in that the sperm is injected into the vagina, and not into the uterus. At independently conducting After insemination, the kit cannot be reused; it is prohibited to lubricate the labia with saliva or cream, or to inject sperm directly into the cervix.

Efficiency of the method

Positive result during the intrauterine artificial insemination procedure is achieved less frequently than with in vitro fertilization(IVF) and ranges from 3 to 49% (these are the most positive data). In practice, the number of attempts is limited to 3–4, since larger number the sample is considered ineffective. After this, it is necessary to conduct additional research or treatment adjustments. If pregnancy does not occur, you should resort to another method artificial conception or change sperm donor.

Risks and possible complications

As such, intrauterine insemination does not cause complications; women are more at risk due to taking medications that cause ovulation, so it is necessary to conduct tests for the possibility of allergies. In addition, the risk of having twins, or less often triplets, increases, due to the fact that several attempts are made to introduce sperm and stimulate the formation of more than one follicle.

Contraindications

Although artificial intrauterine insemination is a simple procedure with virtually no consequences, there are still some restrictions due to which it may be refused. Among them are problems with ovulation itself, which occurs with disturbances, tubal infertility(it is necessary that at least one intrauterine labor is capable), inflammation of the appendages and uterus, hormonal imbalances, infectious and viral diseases.

Price

It is impossible to say definitely how much artificial insemination costs, since prices will differ in each clinic in Moscow. It is important to understand that the procedure consists of several stages, including consultation, tests, and treatment. It is necessary to take into account the price of the medications that you will have to take. If donor sperm is used, then its cost should be added to the price. Today, according to the information provided on the Internet, the following figures can be cited: