Nicotinic acid medicinal properties. Nicotinic acid: harm to hair

Vitamin B 3 (niacin, nicotinamide) - the only one that has been officially assigned the status of a drug, is a powerful antioxidant and is involved in all metabolic processes of the human body.

Description

Structural formula of nicotinic acid

It has two active forms, closely related and sometimes replacing each other, and several names. B 3 - since it was discovered by the third in the family of the B-complex. PP - "against pellagra" - by the name of the disease that develops due to its deficiency. Niacin- by the name of provitamin. Nicotinamide- by the name of its amide. B 3 and PP are now considered obsolete names.

The organic substance is a white soluble powder. Its stability is high in acidic, alkaline environment, autoclave (hot steam under pressure), ultraviolet rays. It tolerates storage in frozen, canned, dried form. Excess consumption of sweets, sugar destroys it.

The intestinal flora of the human body is able to synthesize niacin from tryptophan.

Of all the vitamins, only its medicinal properties are appreciated by the medical community, and the drug officially recognized as a drug.

IMPORTANT! For its mild calming effect on the central nervous system, doctors called niacin the “calm vitamin.”

Differences between nicotinic acid and nicotinamide

Both forms of the substance are able to satisfy the body's need for this biologically active substance, but they have different therapeutic effects.

Nicotinic acid (niacin) dilates blood vessels, is used for diseases of the cardiovascular system. Entry into the bloodstream is accompanied by a surge of heat waves, a feeling of slight pinpoint burning, redness of the head and neck. Contains herbal products.

What is the difference between niacin and nicotinamide?

Niacin is actually nicotinic acid, the main form of the substance.

Nicotinamide is its amide, the second form of the same substance.

They have identical vitamin activity. However, nicotinamide does not have the ability of niacin to modify lipids, lower cholesterol and dilate blood vessels. Consider them separately when used as two different drugs in order to use their different pharmacological properties.

Why does the body need vitamin PP?

Vitamin B3 is needed by the body for the following reasons:

Directly involved in redox processes, a participant in cellular respiration. It is characterized by a pronounced antioxidant effect.
Involved in everyone metabolic processes, contributes to the production of intracellular energy.
Provides health skin, mucous membranes, eliminates bad breath from the mouth.
Expands large blood vessels, lowering blood pressure. Increases the lumen of capillaries, providing good nutrition to all cells of the body. It inhibits the formation of "bad" and increases the proportion of "good" cholesterol, reduces the amount of lipoproteins, triglycerides. Prevents the formation of blood clots, reducing blood viscosity. In general, niacin resists atherosclerotic vascular changes.
Increases cerebral blood flow, sharpens attention, memory. Has a mild sedative effect.
Significantly increases the production of gastric juice.
Parenteral (intravenous) administration of the vitamin stimulates the work of the adrenal glands. As a result, the production of glucocorticoids, which have the ability to suppress local inflammatory and allergic reactions, increases.

When planning a pregnancy

During pregnancy planning, you can take vitamin PP through complex vitamin preparations: Duovit, Vitrum, Biovital, Centrum, Gendevit. Special increased dosages during this period are not provided: the body does not store vitamins for future use, and an excess of vitamins is no less dangerous than their deficiency.

Daily rate

The daily requirement for a vitamin depends on age (see table).

Table of daily content in the body.

Release forms

Nicotinic acid (niacin) is produced in powder, tablets with a dosage of 500 mg, 1% sterile solution. Analogues: VitaplexN, Nikovit, Pellagramin, Enduracin.
Nicotinamide - in powder, tablets with a dosage of 5 and 25 mg, in 1%, 2.5%, 5% solutions.

Indications

If the diet is complete, balanced, the body has enough vitamin that enters the body with food. But there are conditions that require its additional introduction from the outside:

The increased need of the body: when carrying and feeding a child, with severe physical, intellectual, mental stress.
Prolonged depression due to a lack of tryptophan, which the body has to spend not on creating the happiness hormone (serotonin), but on the synthesis of a vital vitamin.
The first symptoms of vitamin deficiency appear: persistent headaches, nervousness, weight loss, skin is pale and dry. If you do not make up for the deficiency of niacin, pellagra, the “three d” disease, can develop: dermatosis - diarrhea - dementia (skin inflammation - loose stools - dementia).
Diseases of the cardiovascular system (arterial hypertension, atherosclerosis).
Diseases of the skin and mucous membranes (stomatitis, dermatitis, acne, acne, eczema).
Diseases of the digestive system: hypoacid gastritis, hepatitis, cirrhosis of the liver.
CNS pathologies: psychoneurological and psychoemotional personality disorders: alcoholism, schizophrenia, depression, smoking.
Diabetes mellitus type I.
Difficult-healing trophic ulcers.

Contraindications

You can not use the drug in case of individual intolerance.

Oral intake: acute period of gastritis with increased secretion, peptic ulcer of the stomach and duodenum; children under 2 years of age.

Parenteral administration: unstable arterial hypertension; gout; severe forms of atherosclerosis, liver diseases; hyperuricemia; children under 2 years of age.

Carefully: tendency to bleed; glaucoma; gastritis with increased secretion, peptic ulcer of the stomach and duodenum without exacerbation.

Side effects

Both oral and parenteral administration of nicotinic acid is accompanied by more or less pronounced symptoms: hot wave tide to the upper part of the body, a feeling of light point tingling; nicotinamide does not cause these manifestations.

Subcutaneous and intramuscular administration of nicotinic acid is accompanied by a pronounced local soreness; nicotinamide is devoid of this side effect.

Possible appearance nausea, vomiting, diarrhea; increase in blood sugar and uric acid; headache, dizziness; myalgia, paresthesia.

With prolonged use, the development of fatty degeneration of the liver is possible.

IMPORTANT! Rapid intravenous administration of niacin provokes a rapid decrease in blood pressure up to the development of orthostatic collapse.

Compatibility of nicotinic acid with other vitamins

Nicotinic acid and vitamin C have positive compatibility. Co-administration with ascorbic acid potentiates action both vitamins. Usual dosages for combined use should be reduced.

Compatibility with B vitamins

Vitamin B1

Nicotinic acid and vitamin B1 have negative compatibility. Niacin has a destructive effect on thiamine (B 1). Recommended separate reception

Vitamin B6

Nicotinic acid and vitamin B6 have positive compatibility. Pyridoxine (B 6) facilitates the absorption of niacin, it is possible simultaneous reception.

Vitamin B12

Nicotinic acid and vitamin B12 have negative compatibility. The joint intake of niacin and cyanocobalamin (B 12) destroys the latter. Recommended separate reception at intervals of at least 6 hours.

Taking roaccutane along with nicotinic acid (vitamin B3)

Roaccutane (ROA) is a powerful drug that has many limitations, side effects, and special indications. Patients undergoing ROA treatment should be under the constant supervision of a doctor. Only a dermatologist decides on the need to prescribe additional drugs.

The use of nicotinamide in cosmetics

Nicotinamide is used as a powerful antioxidant that relieves skin irritation. Protects the skin from the action of ultraviolet radiation, acts as a stimulator of cellular metabolism, improves its blood supply.
Included in products that care for irritated, sensitive, aging or pigmented skin. Well proven in the treatment of rosacea and acne.
Contains nicotinamide sunscreens, bath and shower products, mouth rinses.

The use of nicotinic acid for hair growth

Vitamin, nicotinic acid, is recognized as an effective and low-budget stimulant Hair Growth. The result of the impact is to improve the blood supply to the hair follicles, their additional nutrition. Niacin helps to retain moisture in the hair, preventing them from drying out, eliminates dandruff and seborrhea.

Mode of application

Apply the solution from the ampoule to the roots of washed and dried hair, massaging the skin (the hair itself does not require processing) and put on a warming cap. Keep 1.5 - 2 hours. If the substance is administered as a mask ingredient - no longer than 30 minutes. After the required time, rinse with warm water.

The frequency of procedures is 2 times a week, the course is 30 days; repetitions of courses with a two-month interval are possible. The daily dose for external use is 4 ampoules (or 8 powdered tablets).

IMPORTANT! Local allergic reactions are possible! Before use, you need to do a skin test: apply to the skin of the wrist from the inside, hold for 60 minutes. Monitor the reaction (appearance of itching, burning, redness, swelling). If there are manifestations, then this remedy is not for you.

What products contain

100 g of white mushroom contains 8.5 mg of vitamin PP

The highest content (more than 10 mg per 100 g of the product) is in the liver, cheeses, yeast, offal (heart, kidneys), coffee beans.

Vitamin B3 is present in some herbs: burdock root, chamomile, raspberry leaves, red clover, parsley, peppermint, rosehip, sorrel, ginseng, fennel seeds.

See the full table with products in a separate article:

Useful video

Video about the benefits and harms of nicotinic acid for hair:

Conclusion

Niacin (nicotinamide) is a drug. For therapeutic purposes, it should be used only as directed by a doctor. The use of complexes containing the vitamin in standard dosages does not require medical supervision.

Today, vitamin B3, vitamin PP, or nicotinic acid (all these are synonymous names for the same substance) are used in the prevention and treatment of many diseases. In addition, the tool has found wide application in the fight against hair loss, restoration of hair follicles, stimulation of the growth of beautiful, thick curls. In this article, we invite you to consider how nicotinic acid is useful for women, what the lack of this vitamin leads to, and in what cases its use is contraindicated.

From Cholesterol Stabilization to Migraine Prevention

To begin with, talking about the benefits of nicotinic acid for women, it should be noted that it is under the action of vitamin B3 that sugars and fats in the cells of the human body are transformed into energy. This is an important condition that ensures the normal functioning of cells, and hence tissues and organs of the human body.
In addition, it is thanks to vitamin PP that the enzymes necessary for the production of female sex hormones are activated.
Due to the above actions, the substance normalizes the ratio of lipid fractions, the content of cholesterol and triglycerides in the blood. Under the influence of nicotinic acid, blood vessels expand, which leads to an improvement in blood microcirculation in various tissues and organs. With the help of vitamin B3, it is possible to control the amount of cholesterol in the blood, reduce the risk of thrombosis, avoid the development and worsening of the course of cardiovascular diseases.
Also, the undoubted benefits of nicotinic acid for women are explained by the ability of vitamin PP to reduce pain and increase the mobility of diseased joints in arthritis and arthrosis.
Currently, vitamin B3 is used even in the treatment of diabetes. Due to nicotinic acid, it is possible to reduce the dosage of insulin prescribed to patients.
Even in the last century, doctors discovered that nicotinic acid has a powerful effect in the treatment of pellagra. This type of beriberi, even today, is common in Africa and South America. The main reason for the development of pellagra is long-term malnutrition.
The benefits of nicotinic acid for a woman's body are due to the ability of vitamin PP to relieve skin redness and irritation. The substance is used to combat acne, inflammation.
Representatives of the fair sex successfully use vitamin PP to correct weight. A substance that helps control cholesterol levels also helps to increase metabolism, cleanse blood vessels, and remove toxins and heavy metals from the body. But, of course, you should not expect a miracle: without a proper diet and moderate physical activity, nicotinic acid will be powerless. Only by combining diet, exercise and vitamin intake, you can achieve the expected result.
It is also important that vitamin B3 has a calming effect. It is noted that with its help it is possible to increase the effectiveness of drugs prescribed to patients suffering from depression, schizophrenia, anxiety, patients undergoing treatment for alcohol dependence. Taking niacin regularly can help prevent migraines.

How to recognize a vitamin deficiency?

The daily intake of vitamin for women varies depending on age. So, it is enough for teenage girls to consume about 18 mg of nicotinic acid per day. Adult women over eighteen need 20 mg per day. And for pregnant women and nursing mothers - 20-25 mg per day.

The first signals indicating a lack of nicotinic acid in the body will be fatigue, constant bouts of dizziness, lethargy, unreasonable irritability, loss of appetite, weight loss, dryness and pallor of the skin, palpitations, headaches, weakened immunity.

A long-term deficiency of a vitamin so important for our health can cause the development of pellagra and the corresponding unpleasant symptoms.

The benefits of nicotinic acid for women in hair care

It's no secret that the fair sex pays special attention to their appearance. In an attempt to give the curls a beautiful, well-groomed look, the ladies spare neither time nor money. Speaking about why women need nicotinic acid, one cannot fail to mention the use of vitamin B3 as a cosmetic product to strengthen and stimulate hair growth. An inexpensive remedy, sold in almost every pharmacy, helps to awaken dormant hair follicles, increases blood circulation in the cells of the scalp, and in the tissues - metabolic processes. As a result, hair loss is prevented, curls become noticeably thicker and stronger. Nicotinic acid does not dry the skin even with repeated use.

As a cosmetic product, vitamin B3 is applied directly to the scalp with massage movements. The course of application is 14 procedures. The product must be used on clean, washed hair. Preferably slightly dried. You can use both a liquid remedy and a vitamin in the form of tablets. However, in the first case, you will not need to crush the tablet to a powdery state, and then mix it with water until a homogeneous consistency. Applying a ready-made liquid composition is much easier.

Who should not take nicotinic acid?

Taking the vitamin orally or by injection is contraindicated in peptic ulcers, gout, liver diseases or disorders, hypertension, and severe atherosclerosis.

Useful properties of nicotinic acid (niacin)

Power generation

Niacin is involved in a large number of chemical reactions, the body's reserves of energy. In particular, it converts proteins, fats and carbohydrates into usable energy. Nicotinic acid is also used to synthesize starch, which can be stored in the body's muscles and liver for later use as an energy source.

Fat metabolism

Vitamin B3 plays an important role in the chemical processing of fats in the body. Cell membrane formation requires fatty acids, which in turn require the presence of vitamin B3 for their synthesis. Niacin also causes the synthesis of hormone-like substances that regulate the metabolism in the body.

Normalization of cholesterol levels

Vitamin B3, according to studies, reduces the level of bad cholesterol, which disrupts blood circulation and leads to atherosclerosis. Niacin also reduces the amount of lipoproteins and triglycerides. At the same time, niacin is able to increase the level of good cholesterol. With these features reduces the risk of cardiovascular disease.

Support for genetic processes

DNA components require nicotinic acid for their production, and its deficiency (as well as the deficiency of other vitamins of the group) is directly related to genetic damage. The association between vitamin B3 and DNA damage appears to be particularly important in the context of cancer and its prevention.

Regulation of insulin activity

According to some studies, niacin is able to regulate insulin metabolism and blood sugar levels.

Improving brain function

Back in the middle of the last century, a study was conducted, according to which vitamin B3 in therapeutic doses can increase the percentage of remission among patients with schizophrenia. Niacin also has a mild sedative effect.

Video about vitamin B3

Eggs - 0.19 mg.

What is vitamin B3 for?

1. In order for the body to produce energy. Thanks to nicotinic acid, enzymes are formed in the body. And they are helpers of cells in the conversion of carbohydrates into energy.

2. For the digestive system. Vitamin PP is a direct participant in the breakdown of proteins, fats and carbohydrates, thereby helping the stomach to digest food more easily.

3. Vitamin B3 maintains optimal blood glucose levels. That is, if your day went smoothly and by the evening you are still full of energy, then nicotinic acid will not do anything. But in the case when, after a hard workout or physical exertion at work, your strength slowly leaves you and the only desire left is to go to bed and fall asleep, the action of vitamin PP is activated. He takes out energy reserves from pantries that allow you to finish the day with dignity, and not like a soft toy - where you put it, it will lie there.

4. You know that bones need calcium. Only in this case they will grow stronger and develop normally. The same can be said about the brain and vitamin B3. The first needs it, because without nicotinic acid it cannot work properly - and you suffer. Because: - remember less; - associative thinking is turned off; - the dream does not go.

That is why doctors prescribe vitamin PP when a person suffers from schizophrenia or other illnesses associated with a mental disorder.

Minimum daily intake of vitamin B3

Children:- from six months to a year - 6 mg; - 1.5 years - 9 mg;

The benefits of vitamin B3 or nicotinic acid

Vitamin B3 has many names: nicotinamide, nicotinic acid, niacin. It is one of the most important vitamins for the human body. In addition, nicotinic acid is also used as a drug. The benefits of vitamin B3 or nicotinic acid have long been proven by scientists and are very extensive. Read more about the beneficial properties of nicotinic acid in this article.

Vitamin B3 has many names - niacin, nicotinic acid, nicotinamide, vitamin PP - an abbreviation for "warning pellagra". This substance plays an important role in the functioning of the human body, maintaining its health. Nicotinamide is especially important for maintaining healthy skin. The benefits of vitamin B3 are expressed in its participation in metabolism. If this vitamin substance is present in the body in insufficient quantities, rather unpleasant symptoms occur.

Nicotinic acid is of great importance for redox processes, tissue respiration, carbohydrate and protein metabolism. It has vasodilating properties, and also has the ability to improve the secretion of gastric juice.

It is also worth noting another important role of nicotinic acid - its effect on the functioning of the nervous system. The benefit of vitamin B3 is that it ensures the stability of nervous activity. With its deficiency, the nervous system is vulnerable, unprotected.

Nicotinamide prevents skin disease such as pellagra, or rough skin. In addition, it is an important necessary link in the synthesis of genetic material, protein metabolism, the synthesis of fatty acids and useful cholesterol, and also contributes to the normal functioning of the central nervous system and brain.

The benefit of vitamin B3 also lies in the fact that it is a very effective tool designed to normalize blood cholesterol. This vitamin substance helps to maintain the efficiency of the heart, as well as increase blood circulation.

Nicotinic acid is a participant in many reactions associated with the conversion of fats and sugar into energy. It has a beneficial effect on the functioning of the cardiovascular system, promotes the expansion of peripheral blood vessels, improves blood circulation, cleanses the vessels of dense lipoproteins, reduces pressure, and reduces the likelihood of developing cardiovascular diseases.

Vitamin B3 is used in the treatment of the following diseases:

Diabetes. Nicotinamide prevents the destruction of the pancreas, which leads to the fact that the body loses the ability to produce insulin on its own. Patients diagnosed with diabetes when taking vitamin B3 need injections with less insulin.

Neuropsychiatric disorders. Vitamin B3 has a calming effect, and therefore it is used in the treatment of decreased attention, depression, schizophrenia, and alcoholism.

Osteoarthritis. With the help of nicotinic acid, they reduce pain and joint mobility during illness.

Pellagra. Vitamin PP is used to prevent this skin disease associated with the development of various dermatitis, inflammatory lesions of the mucous membranes of the tongue and mouth, atrophy of the mucous membranes of the gastrointestinal tract.

Sources of nicotinic acid

The benefits of vitamin B3 are most pronounced if a person receives it with natural products, and not with synthetic drugs. The following foods contain nicotinic acid: meat, liver, fish, vegetables, milk, and also cereals.

In addition, nature provides for the possibility of independent synthesis of vitamin B3 by the human body. It is produced from the amino acid tryptophan. That is why experts recommend saturating the diet with foods that contain tryptophan. These are bananas, oats, sesame, pine nuts.

Dosage of vitamin B3

The need for nicotinic acid for an adult is 12-25 mg per day. The dosage depends on the age of the person, his physical activity, the presence of certain diseases. During pregnancy or breastfeeding, with intense physical, mental stress, with nervous strain, while taking antibiotics and other drugs, in very hot or, conversely, cold climates, the dosage of vitamin B3 should be increased.

Nicotinic acid deficiency

Lack of nicotinic acid provokes a lot of unpleasant symptoms. This state is evidenced, first of all, by a variety of emotional manifestations, such as anxiety, fears, aggressiveness, irritability, decreased concentration, anger, weight gain.

In addition, a deficiency of nicotinic acid can lead to headache, weakness, insomnia, irritability, depression, decreased ability to work, digestive disorders, nausea, and loss of appetite.

In order to avoid such manifestations, it is necessary to carefully monitor nutrition and be sure to include foods rich in nicotinic acid in the diet.

An excess of nicotinic acid

An overdose of vitamin B3 usually does not provoke any dangerous consequences. Sometimes it causes slight dizziness, facial redness, muscle tingling, and numbness. With prolonged overdose, fatty degeneration of the liver, stomach pain, loss of appetite can be observed.

In addition, people with exacerbations of peptic ulcer, complex liver damage, severe forms of hypertension and atherosclerosis, gout, excess uric acid in the blood should know that taking vitamin B3 is contraindicated for them.

As for harm, it occurs in the case of an allergic reaction and stomach ulcers. In this case, it is better for a person not to take vitamin B3.

Nicotinic acid for hair growth

Now let's talk about the non-standard use of vitamin B3. Most girls want to have long beautiful hair. Therefore, they are looking for all sorts of natural ways to activate hair growth. Note that inexperience in this case can play a cruel joke on you.

As mentioned above, not all people understand that vitamins are, first of all, drugs that also have an impressive list of contraindications and side effects. But here, when buying, the very word "vitamins" plays a decisive role, which, unlike "antibiotics", allegedly does not involve a risk to health.

So, girls sometimes take both nicotinic acid tablets and rub the contents of the ampoule into the scalp. And in that, and in that method of application, you harm your body.

If you take the pills on an empty stomach, you can become a victim of severe nausea and vomiting. And an overdose (when taking 2 tablets a day) leads to an allergic reaction, which manifests itself in the form of hives on the body and a rash on the face. Agree, the picture is not the most pleasant, and, moreover, the end does not justify the means.

Many girls who used nicotinic acid ampoules noted that after rubbing it they had a severe headache that did not go away within 1-2 days. And this happens because vitamin B3 in large quantities increases blood pressure, and the heart begins to "pump" blood intensively. And such a load on the vessels is simply dangerous.

But what about hair? Is there an effect, given the suffering that the fair sex had to go through? The thing is, you can't see it instantly. It takes some time here. But it is considered the norm when hair grows 1-2 cm per month.

And to speed up this process, you can use an alternative, and, most importantly, safe way - use pepper tincture.

Thus, a vitamin such as nicotinic acid should only be used as prescribed by your doctor, and not on personal initiative, which, as you know, is punishable. And here you will almost have to pay with your health, which is priceless!

Read about health:

The use of nicotinic acid

Nicotinic acid has nothing to do with cigarettes. This is vitamin PP, one of the components of the B-complex. Nicotinic acid has a beneficial effect on the human body, it is used both in medicine and in cosmetology.

Properties of nicotinic acid

Without nicotinic acid, the human body would not be able to function normally. It affects metabolic and educational processes:

improves liver function;
restores the hematopoietic system in the bone marrow;
dilates blood vessels;
lowers blood sugar levels;
improves the functioning of the cardiovascular and central nervous systems.

Scientists have proven that after the use of nicotinic acid, lipid metabolism improves, in addition, in patients with atherosclerosis and hypercholesterolemia, the level of cholesterol in the blood decreases. With pellagra, after the first intake of a course of acid, the effect of treatment is already visible. At the same time, not only this disease is eliminated, but diseases of the gastrointestinal tract and the central nervous system also disappear in parallel, the skin is cleansed. After three weeks from the start of the course, the manifestations on the skin practically disappear, and intestinal and stomach disorders stop. After two months from the start of therapy, a person completely gets rid of pellagric psychoses. It is also popular to use this remedy for weight loss and hair beauty.

For the drug to work, it is necessary to choose the right dosage and method of taking it, prescribe nicotinic acid in the form of tablets or dragees, as injections intramuscularly, intravenously or subcutaneously. These injections are very painful, so they are rarely prescribed.

The dosage is prescribed by the doctor, based on the disease that should be cured. Usually nicotinic acid is taken 0.1 g at a time three times a day. All tablets are taken after meals. As a preventive measure, nicotinic acid is taken in a smaller dosage - 0.020 g at a time, also three times a day.

Injections with nicotinic acid are done twice a day, 0.1 g intramuscularly and half the dose - intravenously. The course of treatment with the drug depends on the complexity and type of the disease. It can last from 3 to 5 weeks, then there is a break for 2 weeks and you can continue taking it again. MirSovetov does not recommend exceeding the daily dose of the drug - 5 grams for tablets and 0.3 grams for injections.

Nicotinic acid for hair

Due to its ability to dilate blood vessels, nicotinic acid is widely used for hair care. After the drug is applied to the hair roots, it is absorbed by the scalp and delivered to the skin cells through the blood vessels, enriching them and the hair follicles with nutrients. This method is the property of traditional medicine, sometimes trichologists also recommend it.

For one course of treatment, you need to purchase 30 ampoules. The ampoule must be opened and, without delay, transfer the liquid into a small container with a syringe. Everything must be done quickly, as the drug loses its beneficial properties in the air very quickly. It is necessary to apply the drug only on a clean head, especially for those with oily hair, since fat can become an obstacle to the penetration of the vitamin into the hair. Silicone shampoo is also not necessary during this period. It is necessary to apply the drug on slightly damp hair so that it is evenly distributed.

You can apply liquid to the hair with a syringe without a needle or with your fingers, first covering the temporal part of the head, then along the partings and along the entire length of the hair. It is best to use one ampoule, although at first glance it may seem small. It's okay if the solution does not get on the entire part of the head or there are gaps, because, getting into the blood, nicotinic acid will be distributed over the entire surface of the skin.

After applying the drug, a slight burning sensation and redness of the skin is possible, as it should be. If there is hives, itching and headache, then the person has an individual intolerance or allergy. You should immediately wash your hair thoroughly and do not use more nicotinic acid.

It is not necessary to wash off the drug from the hair, it will not leave impurities. This procedure must be repeated daily for a month. Then you should take a break for a month. Judging by the reviews of the girls, such a procedure can provoke hair growth of up to three centimeters per month.

Nicotinic acid for skin

Without nicotinic acid, oxygen exchange would not occur in skin cells. In addition, it dilates blood vessels and improves blood circulation, as a result of which the skin looks elastic and healthy. It also works well on edematous skin, removes excess fluid from the cells. Therefore, all decongestant cosmetics, as a rule, contain nicotinic acid.

This vitamin also participates in protein metabolism, in the formation of collagen and elastin, which make the skin smooth, elastic and well-groomed. Also, acid affects the formation of sex hormones in women, when their level in the body is high, wrinkles do not appear on the face. It is useful to use cosmetic products with nicotinic acid in sunny weather, as this drug reduces the risk of melanoma due to ultraviolet radiation.

Nicotinic acid is also useful in the fight against cellulite. For thermoactive wrapping, you need to dilute the drug ampoule in water in a ratio of 1:3. Soak a wide bandage in this solution and wrap it around problem areas. Wrap tightly, but not tight. Wrap the top with cling film and a warm towel or blanket. The skin should warm up well, and even better - sweat. You need to start the procedure from 15 minutes, if the skin responds well to wrapping, then the time can be increased. In cosmetology stores, bandages with ready-made impregnation are sold. Their width is about 15 cm, one package is enough for several procedures. In addition to nicotinic acid, the wrapping liquid contains essential oils, caffeine, and plant extracts.

Contraindications and side effects

When taking nicotinic acid, side effects may occur:

redness on the skin;

Nicotinic acid is a provitamin of nicotinamide (a water-soluble anti-pellagric B vitamin).

Today, this drug is available in several forms:

nicotinic acid in tablets of 0.05 g (50 tablets per pack);
dragees in a dosage of 0.005 g or 0.015 g (50 pieces per pack);
1% solution - injections of nicotinic acid, on sale in ampoules of 1 ml;
powder in sticks of 0.015 g.

Pharmacological properties of the drug

Nicotinic acid is an extremely important vitamin for our body, contributing to the normal course of most metabolic and educational processes. It improves liver activity, has a trophic, healing effect on wounds and ulcers, stimulates the hematopoietic function of the bone marrow, eliminates spastic conditions of blood vessels, activates the production of the gastric mucosa and gastrointestinal motility, facilitates detoxification processes, and reduces blood glucose. Also, the use of nicotinic acid has a beneficial effect on the functioning of the heart, blood vessels and the central nervous system.

It has been proven that the use of nicotinic acid has a beneficial effect on lipid metabolism, and also significantly lowers blood cholesterol levels in patients with hypercholesterolemia and atherosclerosis.

The use of nicotinic acid in pellagra is extremely effective. With the first course of taking the drug, a rapid therapeutic effect is noted. At the same time, positive dynamics is noted both from the side of gastrointestinal and skin phenomena, and from the side of the central nervous system. After three weeks of therapy, skin symptoms completely disappear, dyspepsia (gastrointestinal disorders) stops. And within two months of treatment, pellagric psychoses completely disappear.

However, this is not a complete list of the useful properties of this drug. The use of nicotinic acid is effective as an antipruritic, detoxifying, desensitizing, vasodilating agent. Nicotinic acid for hair is actively used. The use of nicotinic acid for weight loss is also popular.

Rules for the use of nicotinic acid

Tablets and injections of nicotinic acid are prescribed for liver diseases, for multiple sclerosis, and also as a vasodilator for endarteritis and other processes associated with angiospastic phenomena.

Vitamin PP is often used in the treatment of diseases of the skin and mucous membranes: eczema, photodermatosis, lupus erythematosus, neurodermatitis, dermatitis, psoriasis, parapsoriasis, skin porphyria, cheilitis, aphthous stomatitis, glossitis. This drug is also used in the treatment of dermatoses that cause peripheral circulatory disorders.

Vitamin PP is used as a detoxifying agent for the treatment of sulfonamide poisoning, as well as in long-term therapy with antimalarial and anti-tuberculosis drugs.

Often this substance is also used as a diagnostic tool for the detection of syphilitic roseola and erythema leprosy.

In the treatment of various diseases and disease states, the correct dosage and method of taking the drug should be prescribed. The drug can be administered orally (nicotinic acid in tablets or dragees), administered intramuscularly, subcutaneously or intravenously (injections). Given the pain of injections of nicotinic acid, the drug is rarely prescribed intramuscularly and subcutaneously.

Usually, nicotinic acid tablets are prescribed at a dosage of 0.02-0.1 g per dose up to 3 times a day. They should be taken after meals. For prophylactic purposes, nicotinic acid tablets are prescribed at a dosage of 0.015-0.025 g per dose, three times a day (adults) and 0.005-0.02 g per day (children).

Injections of nicotinic acid (1% solution of 1-5 ml) are usually administered intramuscularly at 0.1 g or at a dosage of 0.05 g (intravenously) 1-2 times a day. Niacin injections for children are prescribed intramuscularly at the rate of 0.002–0.003 g per 1 kg of body weight once or twice a day.

Depending on the complexity and type of the disease, the duration of the course of treatment can be from three to five weeks, if necessary, a second course of treatment is prescribed after a 10-14-day break. The maximum daily dose when using injections is 0.3 g, when taken orally up to 5 g.

The drug has low toxicity and in most cases is well tolerated by patients.

Nicotinic acid for hair

The benefit of nicotinic acid for hair lies in the ability of this drug to dilate blood vessels. That is, when applied to the hair roots, this substance is absorbed into the scalp and, thanks to the blood vessels, is supplied to the cells of the skin on the entire surface of the head, enriching the skin and hair follicles with essential nutrients. To strengthen the hair and improve their growth, it is necessary to conduct a 30-day course of therapy. Of course, such techniques are not prescribed by the attending physicians, unless the trichologist can recommend them to strengthen the hair. But for the most part, this therapy is a find of traditional medicine and this recipe is passed "by word of mouth" as recommendations. So how is nicotinic acid used for hair? Everything is quite simple: a small amount of the solution is applied to the scalp, rubbing it with light massaging movements. A ready-made solution in ampoules is used, it is not necessary to dilute it. At a time, it is necessary to use no more than 1 ampoule, it should be applied literally drop by drop to different parts of the head: in the temporal zone, on the back of the head, along the parting line. It is better to pour the contents of the ampoule into a plastic container and, dipping your fingertips into the solution, apply the product to the scalp. This procedure is done daily after shampooing for 30 days. However, do not use more than 1 ampoule per day and exceed the course of rehabilitation therapy, otherwise you can cause an allergic reaction. In this case, temporary redness of the scalp after applying the drug is considered normal.

Nicotinic acid for weight loss

It must be said right away that nicotinic acid for weight loss is not used as a fat-burning agent. This drug does not have the ability to burn fat cells, but it perfectly normalizes metabolic processes in the body, stimulates the production of a sufficient amount of gastric juice and lowers blood cholesterol levels. Effective nicotinic acid for weight loss and the fact that it will help cleanse the body of toxins and toxins, normalize blood circulation and saturate the body with useful substances.

Side effects and contraindications

With the rapid introduction of the drug, there may be weakness, a decrease in blood pressure, a deterioration in appetite. Quite often, after taking the drug, there may be a temporary reddening of the skin of the face, fever, a feeling of a rush of blood to the head. However, these events pass quickly.

Instructions for use:

Nicotinic acid is a vitamin preparation, also referred to as vitamin PP.

pharmachologic effect

Nicotinic acid is a compound similar in structure to nicotinamide.

The use of nicotinic acid is important for stimulating blood circulation, brain activity, the metabolism of amino acids, fats, carbohydrates, and proteins.

This vitamin is of great importance for the prevention of cardiovascular diseases. It helps to reduce the level of cholesterol, lipoprotein and triglyceride - substances that clog blood vessels, increase pressure and the formation of blood clots, limit blood supply.

Release form

Release nicotinic acid in tablets, in the form of a solution.

Indications for the use of nicotinic acid

Vitamin is administered intravenously, taken orally, subcutaneous and intramuscular injections of nicotinic acid are made.

The agent is used for the treatment and prevention of pellagra, the treatment of mild forms of diabetes, heart disease, gastrointestinal ulcers, liver, enterocolitis, gastritis with low acidity, poorly healing skin lesions, to relieve spasms of the vessels of the brain, arms and legs, kidneys.

Also, the agent is included in the complex therapy of neuritis of the facial nerve, atherosclerosis, and various infections.

Contraindications

You can not enter the vitamin intravenously with hypertension, do not use the remedy for hypersensitivity.

With increased individual sensitivity to the drug, you can replace the acid with nicotinamide, except in those cases when the acid was prescribed as a vasodilator.

Application instruction of Nicotinic acid

For prevention, nicotinic acid is prescribed for adults at 15-25 mg, for children 5-20 mg per day.

For the treatment of pellagra, adults take nicotinic acid in tablets of 100 mg up to four r / day for 15-20 days. You can enter a 1% acid solution - 1 ml up to two r / day for 10-15 days. Children are given 5-50 mg two or three r / day.

According to other indications, adults take the vitamin at 20-50 mg, children - 5-30 mg up to three r / day.

As a vasodilator in ischemic stroke, 1 ml of nicotinic acid is administered intravenously.

Intramuscular and subcutaneous injections of nicotinic acid, unlike intravenous administration, are painful. In order to avoid irritation, you can apply the sodium salt of nicotinic acid.

Due to the ability of this vitamin to dilate blood vessels, nicotinic acid is useful for hair - it stimulates their growth. For hair treatment, the solution is rubbed into the scalp for 30 days, 1 ml (one ampoule).

Apply the solution in its pure form, on slightly damp, washed hair. After a month of hair treatment with nicotinic acid, there is a cleansing of the scalp from dandruff, strengthening of the roots, hair grows by 4-6 cm. If necessary, rubbing courses can be repeated periodically, with interruptions of 15-20 days.

Successfully use nicotinic acid for weight loss. Weight correction is facilitated by the fact that the vitamin speeds up metabolism, helps cleanse blood vessels, even out cholesterol levels, and remove heavy metals and toxins. The dosage of nicotinic acid for weight loss for each person is individual, and is 100-250 mg per day. They usually take nicotinic acid in tablets, no more than 1g per day, several times a day. A reaction to acid is considered normal in the form of reddening of the skin and a flush of heat. With increased acidity of the secretion of the stomach, take the vitamin only after meals.

Side effects

The use of nicotinic acid can cause: redness of the skin of the face, upper half of the body, rash, numbness in the limbs, dizziness, hot flashes. These side effects go away on their own.

With the rapid introduction of a vitamin intravenously, pressure can drop sharply, and with prolonged use and in high dosages, the agent can provoke the appearance of fatty hepatic degeneration. To prevent this disease, the vitamin is prescribed simultaneously with methionine.

Nicotinic acid, produced in tablets and ampoules for injections, has great benefits for the body. This vitamin replenishes the deficiency of substances, improves health, has a positive effect on metabolic processes and energy production. Familiarize yourself with the indications for its use, dosage, methods of administration. The amount of funds used differs according to individual characteristics.

What is nicotinic acid

Vitamin PP, B3 or nicotinic acid is an important substance for the body. Once inside, it breaks down to niacinamide, which is involved in the process of fat metabolism. The main purpose of a vitamin is to convert food into energy. The daily requirement for nicotinic acid is 5-10 mg, for pregnant women - 15 mg. The attending physician prescribes it if indicated.

Benefit and harm

Nicotinic acid is harmful in the form of allergic reactions and stomach ulcers, which are aggravated when it is taken. The benefit of the drug is a positive effect on metabolism and the following effects on the body:

lowers cholesterol levels;
removes toxins;
speeds up metabolism;
reduces inflammatory processes;
nicotine for blood vessels expands them, thins the blood;
prevents atherosclerosis.

Compound

In medical practice, over-the-counter nicotinic acid preparations are used. They are available in the form of powder, tablets and ampoules. It is recommended to store all varieties away from sunlight, out of reach of children. The composition of the preparations includes pyridinecarboxylic-3-acid. It is a white crystalline powder, poorly soluble in cold water and alcohol, but readily soluble in hot water.

pharmachologic effect

Vitamin B3 plays an important role in ensuring the vital activity of the body; it is a component of the prosthetic groups of codehydrase enzymes. The latter carry hydrogen and carry out redox processes. Vitamin B3, getting inside the body and breaking down to nicotinamide, transfers phosphates. Without them, pellagra develops.

Release form

According to pharmacological definitions, the following forms of release of this vitamin preparation are distinguished:

vitamin B3 in ampoules - 1 ml, glass ampoules, pH of the solution for injection 5-7;
powder for injection;
tablets (50 pcs.) - a drug to compensate for acid deficiency, the content of the active substance is 0.05 g;
sodium nicotinate solution -0.1% nicotine solution.

Indications for use

According to the instructions in medicine, the following use of nicotinic acid for medicinal purposes takes place:

Electrophoresis with nicotinic acid - used in the treatment of osteochondrosis. The method quickly removes lactic acid from tissues affected by inflammation, relieves pain and swelling, and enhances the healing process. For the procedure, a 1% solution is used, a course of 10 days, once a day.
For the treatment of pellagra, improvement of carbohydrate metabolism, mild forms of diabetes, diseases of the liver, heart, ulcers, enterocolitis, poorly healing wounds, myopathy.
Lowering the level of lipoproteins in the blood, lowering the concentration of triglycerides, treatment of hypercholesterolemia.
Specific remedy for gastritis, vasospasm, brain.
Stimulates hair growth (30-day course, rub 1 ml into the scalp every day), according to reviews, eliminates dandruff.
For the activity of losing weight, from cellulite - taking tablets of 1 g per day, several times a day.
Prevention of diabetes, reduction of pain in osteoarthritis.
Improving the effectiveness of drugs for the treatment of depression, anxiety.
Body detoxification, migraine prevention.

Nicotinic acid preparations

Vitamin is an integral component of the preparations Vitaiodurol, Vicein, Xanthinol Nicotinate, Lipostabil, Nikoverin, Nikospan, Spazmokor. It is found in two forms - acid and nicotinamide. Both formats are active components of the drugs, have the same pharmacological purpose, a similar therapeutic effect. Nicotinamide is included in the preparations:

tablets and solution for injection Niacinamide;
Nikonacid;
Tablets and solution Nicotinamide;
Apelagrin;
Niacin;
Nikoverin;
Enduracin.

Instructions for use of nicotinic acid

According to the annotation, vitamin PP can be used in the form of tablets (orally after meals) and ampoules (parenterally). As a preventive measure, adults are prescribed 0.015-0.025 g per day. When pellagra is taken for 15-20 days, 0.1 g 2-4 times / day, or injections of a 1% solution of 1 ml are administered twice a day for 10-15 days. For other diseases, adults take up to 0.1 g of the drug per day. If there are no side effects, in the treatment of atherosclerosis and lipid metabolism disorders, a single dose can be increased to 1 g, and a daily dose to 4 g.

Pills

Vitamin PP in tablets is used for long-term therapy and disease prevention. In the first case, they are recommended to be taken in autumn and spring for people with circulatory problems in the lower extremities. It is allowed to take 1-2 tablets three times a day, while using methionine preparations to protect the liver. If the patient has increased acidity of gastric juice, the medication is taken after meals, washed down with mineral water or warm milk.

If you drink tablets before meals, this can provoke discomfort: burning in the stomach, nausea. Dosage depends on age, weight and disease:

for prevention, up to 25 mg / day is taken;
with the appearance of pellagra 100 mg 3-4 times / day in a course of 15-20 days;
with atherosclerosis 2-3 / day, 3-4 doses;
in violation of fat metabolism in the first week, take 500 mg once, in the second twice, in the third three times, the course is 2.5-3 months;
to increase the concentration of high density lipoproteins, take 1 g / day;
to reduce the risk of heart disease 500-1000 mg / day;
courses of therapy are repeated with an interval of a month.

injections

The drugs can be administered as subcutaneous, intravenous or intramuscular injections. Nicotinic acid injections are injected into a vein slowly, in a stream, in a hospital due to the possible risk of severe allergic reactions. Subcutaneous and intramuscular injections are allowed for independent use at home. They are very painful, so you should choose the right place.

The optimal sites for injections are the upper part of the shoulder, the anterior surface of the thigh, the anterior abdominal wall, provided there is no excess weight, the upper outer quadrant of the buttocks. When administered subcutaneously, it is better to put injections in the area of \u200b\u200bthe forearm and the anterior wall of the abdomen. Use for intravenous, intramuscular and subcutaneous injections can be 1.5 or 2.5% solutions administered 1-2 times a day. The dosage depends on the type of disease:

with pellagra and deficiency symptoms - 50 mg intravenously or intramuscularly, 100 mg 1-2 times / day for a course of 10-15 days;
with ischemic stroke - 100-500 mg intravenously;
in other diseases and children use tablets.

How to inject intramuscularly

After choosing a place, wipe it with an antiseptic, draw a solution into the syringe, release a few drops, lifting the needle up to expel air bubbles, inject, treat the puncture site with alcohol or chlorhexidine. For each injection, choose a new place, deviating from the previous 1-1.5 cm. Intramuscular injection is done as follows: insert the needle deeply, slowly press the piston and release the solution.

Nicotinic acid during pregnancy and lactation

If the pregnancy is proceeding normally, vitamin PP is not prescribed. In cases of drug dependence, multiple pregnancy, impaired functioning of the placenta, pathology of the liver and biliary tract, the drug is indicated for use. When carrying a child, the remedy eliminates spasm, improves blood circulation, and reduces its viscosity. Vitamin B3 prevents the formation of blood clots, blockage of placental vessels, reduces the risk of fetal death and premature birth. Tablets are shown to increase lactation, but with caution and monitoring the condition of the child.

Use in children

Children under two years of age should not take ampoule vitamin B3. The child can only be given a tablet format of the drug, orally after a meal with cold drinks, mineral water. Dosage depends on the purpose:

for prevention - 0.005-0.02 g per day;
with pellagra - 0.005-0.05 g 2-3 times a day;
other diseases - 0.005-0.03 g 2-3 times a day.

Nicotinic acid and alcohol

Practitioners and scientists note the intoxication effect of vitamin B3. It helps to quickly remove toxic substances from the body, binds free radicals, and neutralizes the effect of poisons on the cells of organs and tissues. The drug is widely used in the removal of a hangover syndrome, in the treatment of alcoholism and drug addiction, exposure to harmful substances in the workplace.

drug interaction

Before prescribing vitamin PP, tell your doctor if you are taking any other medications, as it has the following drug interactions:

when combined with fibrinolytics, cardiac glycosides and antispasmodics enhances the effect;
while taking barbiturates, neomycin, sulfonamides, anti-tuberculosis drugs, it is accompanied by an increase in toxic effect;
increases the risk of side effects when used with antihypertensive drugs, aspirin, anticoagulants;
nicotinic acid develops a toxic effect with lipid-lowering drugs;
reduces the severity of the effect of the anti-diabetic drug system.

Alcohol compatibility

According to the instructions for the use of vitamin B3, it is incompatible with alcohol, preparations that include ethanol. A dangerous effect is an increase in the toxic effect on the liver, a decrease in the absorption of bile acid sequestrants. It is worth refraining from taking alcohol-containing drinks and medicines while taking the drug.

Side effects and overdose

With an incorrectly prescribed dose of vitamin PP, the following side effects may occur:

redness of the face, upper body (when taken on an empty stomach or by persons with hypersensitivity), hot flashes;
dizziness;
urticaria, skin rash;
paresthesia (numbness of the limbs);
lowering blood pressure (with rapid intravenous administration);
gout;
acanthosis;
increased blood sugar levels;
increased frequency of arrhythmia attacks;
Blurred vision due to retinal edema.

Contraindications

Instructions for use of vitamin B3 in ampoules and tablets contain instructions on contraindications:

severe forms of hypertension, atherosclerosis (intravenously);
hypersensitivity to components;
long-term use threatens with fatty degeneration of the liver (you can get rid of this by combining the intake of funds with products rich in methionine, prescribed drugs of methionine or lipotropic action)

special instructions

The annotation embedded inside each package of nicotine contains special instructions that must be followed when taking the product:

high doses of vitamin are contraindicated during pregnancy, lactation;
during therapy, liver function should be regularly monitored;
use nicotinic acid with caution in hyperacid gastritis, ulcers (irritated mucous membrane), hepatitis, cirrhosis, diabetes mellitus;
for the correction of dyslipidemia in diabetics is not used;
at the initial stage of use, the content of fats, sugars, uric acid is monitored;
long-term use threatens to wash out vitamin C.

Analogues

According to the active substance, the following structural analogues of the drug in question are distinguished, having a similar therapeutic effect, produced by domestic or foreign manufacturers:

Niacin;
Nicotinic acid Bufus or Vial;
Enduracin;
Apelagrin;
Liplite;
Nicodon;
Nikonacid;
Nicoten;
Nikovit;
Peviton;
Vitaplex.

Price

Vitamin B3 preparations can be bought in an online store or ordered from a catalog through a pharmacy. The cost depends on the form of release, the manufacturer. Approximate prices: