Drops for the heart Elkar. Dosage and administration

Elkar is a vitamin preparation that takes an active part in metabolism, has a lipolytic effect, and also normalizes gastric secretion.

The main active component of the Elcar solution, levocarnitine, is a natural organic compound that is chemically related to B vitamins. It affects cell metabolism by facilitating the process of transferring certain fatty acids to the mitochondria, where they undergo oxidation with energy release.

By improving metabolic processes in cells, the drug has several positive therapeutic effects.

Clinical and pharmacological group

A drug that improves metabolism and energy supply of tissues.

Terms of sale from pharmacies

Can buy without a doctor's prescription.

Price

How much does Elcar cost in pharmacies? The average price is at the level of 370 rubles.

Composition and form of release

The Elcar solution as the main active ingredient includes the compound levocarnitine (carnifit). Its content in 1 ml of solution is 300 mg. Also, the composition of the drug includes auxiliary components, which include:

• Propyl parahydroxybenzoate.
• Methyl parahydroxybenzoate.
• Citric acid monohydrate.
• Purified water.

The solution is in a 50 ml vial. The cardboard pack contains one bottle of oral solution and annotation.

Pharmacological effect

Elkar contains levocarnitine (carnifit, L-carnitine) - a natural substance related to B vitamins. It is found in the body of a healthy child and takes part in the process of splitting proteins, fats and carbohydrates that come with food. Their chemical "destruction" leads to the release of a sufficient amount of energy, which is spent on the needs of the brain, muscles and other internal organs.

The main biological functions of L-carnitine include:

• normalization of metabolism in the body;
• strengthening the work of digestive enzymes;
• activation of the breakdown of fats with the release of 38.9 kJ of energy for each gram of the substance;
• increased production of adenosine triphosphate (ATP) - a universal source of energy for all biochemical processes in the human body;
• stimulation of protein and carbohydrate metabolism.

Another function of the drug is that it contributes to the normalization of body weight: overweight children become slim in a short time, and thin children quickly gain several kilograms. Children with a normal metabolism better adapt to physical and mental stress, tolerate stress more easily: levocarnitine increases the saturation of brain tissue with oxygen, improves the ability to memorize and concentrate. The extra energy helps kids cope with serious illnesses and recover faster after them.

But there are cases when the production of one's own levocarnitine is disturbed. The fact is that for the synthesis of a substance in the liver and kidneys, a sufficient content is required:

• vitamins B3, B6, B9, B12, C;
• gland;
• amino acids methionine and lysine;
• enzymes that control the rate of a chemical reaction.

Lack of any of these elements leads to a decrease in the content of L-carnitine in the body. The self-produced energy becomes insufficient for the baby, and it is urgently required to receive it from the outside. Then Elkar comes to the rescue, which makes up for the lack of carnifite and starts the processes of energy exchange.

Indications for use

• for the treatment of diseases of the pancreas and liver, digestive disorders, dermatological diseases, hyperthyroidism (in a mild form);
• in conditions accompanied by a deficiency of carnitine in the body;
• in conditions provoked by increased psycho-emotional and physical stress;
• with increased fatigue and decreased performance (in particular, in elderly people);
• in the rehabilitation period after surgery, injuries and past somatic diseases;
• patients suffering from anorexia nervosa syndrome.

The drug is used to treat brain lesions, accompanied by neurological symptoms.

Elkar is prescribed for growth vitamin deficiency, which is caused by diseases associated with impaired metabolism in muscle tissue, mitochondrial diseases or myocardial diseases, accompanied by electrical or mechanical dysfunction of the heart.

For patients with heart disease, taking the drug can increase exercise tolerance. In elderly patients, Elcar slows down the aging process of the brain, improves concentration and higher mental functions.

L-carnitine is also indicated for athletes to improve endurance and performance during training, increase strength and speed, improve coordination, reduce adipose tissue and increase muscle mass faster.

In addition, in sports medicine, the drug is prescribed to prevent and reduce the severity of symptoms of post-training syndrome, as well as to accelerate the regeneration of muscles damaged due to injuries.

The drug can also be prescribed to children born prematurely, as well as children in the period of active growth. Against the background of treatment, the child's appetite improves, body weight normalizes, and the development of skeletal muscles normalizes.

In acute hypoxic conditions (for example, with ischemic stroke, acute cerebral hypoxia or transient ischemic attack); acute, subacute and rehabilitation period of circulatory disorders in the brain; DEP, brain lesions of various origins, after surgical interventions; patients on hemodialysis with a deficiency of levocarnitine in their body; with ischemic disease, hypoperfusion due to cardiogenic shock, and other pathological processes in the myocardium, Elcar can be prescribed intravenously.

Contraindications

Contraindications to the appointment of Elkar are hypersensitivity and intolerance to the components of the drug, high levels of carnitine in the body, severe diseases of the digestive system.

With caution, the drug is prescribed during pregnancy and breastfeeding, in children under 3 years of age.

Dosage and method of application

As indicated in the instructions for use, Elcar is taken orally 30 minutes before meals, further diluted with liquid.

children the drug is prescribed as an additive to sweet dishes (jelly, compote, juices).

1. Children under 3 years old the dosing regimen is set individually. Children from 3 to 6 years old- in a single dose of 100 mg (5 drops) 2-3 times / day, daily dose - 200-300 mg (11-16 drops). The course of treatment is 1 month. Children aged 6 to 12 prescribed in a single dose of 200-300 mg (11-16 drops) 2-3 times / day, the daily dose is 400-900 mg (22-48 drops). The course of treatment is at least 1 month.
2. With growth retardation - 250 mg (13 drops) 2-3 times / day. The course of treatment is 20 days. The course of treatment is repeated after a 1-2 month break or prescribed for 3 months without a break.

Dosages for adults are somewhat different:

1. For adults with prolonged physical and psycho-emotional stress, the drug is prescribed at a dose of 750 mg (1/2 scoop or 2.5 ml) 3 times / day to 2.25 g (1.5 scoop or 7.5 ml) 2-3 times / day.
2. With anorexia nervosa, as well as during the rehabilitation period after illnesses and surgical interventions and injuries - 1.5 g (1 scoop or 5 ml) 2 times / day. The course of treatment is within 1-2 months.
3. In the complex therapy of chronic gastritis and chronic pancreatitis with reduced secretory function, the drug is prescribed 375 mg (1/4 measuring spoon or 1.25 ml) 2 times / day. The course of treatment is within 1-1.5 months.
4. For the treatment of skin diseases - 750 mg (1/2 measuring spoon or 2.5 ml). The course of treatment is within 2-4 weeks.
5. With mild hyperthyroidism, the drug is prescribed 250 mg (13 drops) 2-3 times / day. The course of treatment is 20 days. The course of treatment is repeated after a 1-2 month break or used for 3 months without a break.
6. With brain damage of vascular, toxic and traumatic origin - 750 mg (1/2 measuring spoon or 2.5 ml) / day. The course of treatment is within 3-5 days. If necessary, a second course is prescribed after 12-14 days.
7. In diseases accompanied by a lack of carnitine (primary and secondary carnitine deficiency), the drug is prescribed at a dose of up to 50-100 mg / kg (2-5 drops / kg) of body weight. Multiplicity of reception - 2-3 times / day. The course of treatment is within 3-4 months.

Adults in sports medicine and during intensive training are prescribed 2.5 g 1-3 times / day (daily dose 2.5-7.5 g); in case of use for therapeutic purposes - 70-100 mg / kg / day (5-7.5 g / day). Reception courses: 3-4 weeks in the pre-competitive period, during the training process - up to 6-8 weeks.

Adverse reactions

In general, the solution for oral (oral) use of Elcar is well tolerated. Sometimes, against the background of its reception, the development of several negative reactions is possible, which include:

1. Pain in the stomach (gastralgia).
2. Dyspeptic phenomena in the form of nausea, unstable stool, bloating.
3. The appearance of pain in the muscles (myasthenia gravis), which may occur in patients with a concomitant increase in the concentration of urea (uremia).
4. Allergic reactions - a rash on the skin, accompanied by itching, urticaria, resembling a nettle burn, angioedema angioedema with an increase in peripheral tissues (mainly in the face and external genitalia) in volume due to the release of the liquid part of the blood from the vessels into the intercellular substance.

With the development of negative pathological reactions after the start of taking the Elcar solution, you should contact a medical specialist who will determine the possibility and expediency of its further use.

Overdose symptoms

With the correct dosage of the drug, there is no risk of overdose. If a child accidentally drank a large amount of the drug, he should be vomited as soon as possible by pressing on the root of the tongue. After that, the introduction of enterosorbents and the provision of medical care in a hospital setting are recommended.

special instructions

Treatment of children under the age of 3 years should be carried out under the supervision of a physician.

The drug does not affect the performance of potentially hazardous activities that require special attention and speed of psychomotor reactions (driving a car and other vehicles, working with moving mechanisms, the work of a dispatcher and operator, etc.)

Compatibility with other drugs

With the simultaneous use of corticosteroids, they contribute to the accumulation of carnitine in tissues (except the liver), anabolic agents enhance the effect of the drug.

Elkar (levocarnitine) is a drug that improves metabolism and helps provide tissues with energy. The normal course of metabolic processes in the human body is under constant threat. Stress, excessive physical and mental stress, pregnancy, breastfeeding, dietary errors, surgical interventions, side effects of certain medications - all these factors can have a negative impact on metabolism. Levocarnitine (L-carnitine) is a substance that can ensure normal metabolism and replenish energy deficits. In some sources, it is called vitamin W or B11, but this is not entirely true, because. unlike true vitamins, it can be synthesized in the body. Its biological role is to provide energy to tissues that experience the greatest physiological stress - skeletal muscles, brain, liver and especially the heart (lack of levocarnitine can provoke cardiomyopathy). L-carnitine acts as a carrier of fatty acids to the "energy furnaces" of the body - cellular mitochondria, where they are utilized with the release of a large amount of energy. The lack of this substance is manifested by rapidly developing fatigue, weakened immunity, dyspeptic disorders, and hypersensitivity reactions. In stressful situations, there is an increased elimination of L-carnitine from the body, as a result of which its intake from the outside is necessary. In 2000, pharmaceutical technologists of the domestic company Pik-Pharma created the drug Elcar, the key active ingredient in which is the biological "passionary" - the active L-isomer of carnitine. Subject to the recommended dosing regimen, this drug is able to completely close the "carnitine window" created when this compound is deficient. Good tolerability and a favorable safety profile make the drug affordable even for newborns and elderly patients - the most vulnerable population groups in terms of susceptibility to metabolic disorders and side effects from the use of drugs.

Compliance with the standards of efficacy and safety of the drug is confirmed by clinical studies and almost twenty years of experience in its use for the treatment of diseases associated with metabolic disorders and energy metabolism in children of preschool and school age, pregnant and lactating women, athletes, patients of mature and advanced age, who are most need levocarnitine. Elkar has a complex effect on the body, including:

Strengthens the immune status;

Increases endurance, psycho-emotional stability, physical performance due to the active utilization of fatty acids with the release of energy available for use by the body;

Eliminates increased fatigue, muscle weakness;

Normalizes energy exchange and metabolism;

Changes body composition: increases the proportion of muscle tissue by reducing the proportion of adipose tissue;

Helps to deal with stress;

Normalizes the work of internal organs - the heart, liver, kidneys, as well as the central nervous system;

Stimulates mental and physical development in children;

It slows down the processes of natural biological aging of the body.

Elkar is indispensable in the spring, when hypovitaminosis comes with the first clear and saturated sunny ultraviolet days, all kinds of chronic diseases become aggravated. At this time, it is especially important to bring the body into tone and maintain it in this state, which Elkar will cope with honorably: in 1-2 months of regular intake, it will make up for the lack of levocarnitine, restore working capacity to its previous level, protect against diseases and stress. The fat-burning effect of Elkar is also in great demand: if you follow the diet and regular physical activity, the drug allows you to effectively get rid of extra pounds and make your figure slim and fit.

Elcar is for oral use. The specific dose and duration of the therapeutic course is determined by the doctor on an individual basis. Anabolic drugs potentiate the effects of the drug. Glucocorticosteroids contribute to the accumulation of levocarnitine in tissues (with the exception of the liver).

Pharmacology

Vitamin B group (vitamin B T), an amino acid derivative that is an essential cofactor in fatty acid metabolism. Normalizes protein and fat metabolism. Has anabolic effect. Contributes to the normalization of basal metabolism in hyperthyroidism.

Pharmacokinetics

When taken orally, it is well absorbed. Cmax is achieved after 3 hours, the therapeutic concentration is maintained for 9 hours. When administered intramuscularly, it is found in plasma for 4 hours. After intravenous administration, it disappears from the blood after 3 hours. Easily penetrates into the liver and myocardium, more slowly - into the muscles. It is excreted by the kidneys mainly in the form of acyl esters.

Release form

The oral solution is clear, colorless or slightly colored; presence of a specific smell is allowed.

Excipients: citric acid monohydrate - 1.2 mg, methyl parahydroxybenzoate - 0.5 mg, propyl parahydroxybenzoate - 0.2 mg, purified water - up to 1 ml.

25 ml - plastic bottles (10) - packs of cardboard with partitions.
25 ml - plastic bottles (20) - packs of cardboard with partitions.

Dosage

Taken inside. Doses and duration of treatment are set individually depending on the indications.

Interaction

With the simultaneous use of anabolics enhance the effect of levocarnitine.

With the simultaneous use of GCS, they contribute to the accumulation of levocarnitine in tissues (except the liver).

Side effects

Perhaps: nausea, vomiting, diarrhea, abdominal pain, allergic reactions, muscle weakness (in patients with uremia); with rapid administration (80 drops / min or more), pain may occur along the vein, passing with a decrease in the rate of administration.

Rare: body odor.

Indications

Micropediatrics and pediatrics: malnutrition, hypotension, adynamia, consequences of birth trauma and asphyxia, conditions after serious illnesses and operations. Psychiatry and neurology: anorexia nervosa, physical exhaustion, traumatic encephalopathy. Gastroenterology: chronic gastritis with reduced secretory function, chronic pancreatitis with reduced exocrine function. Endocrinology: growth retardation in children under 16 years of age, mild forms of thyrotoxicosis. Dermatology: psoriasis, seborrheic eczema, scleroderma.

Contraindications

Hypersensitivity to levocarnitine.

Application features

special instructions

The possibility of using levocarnitine for the treatment of mitochondrial myopathy caused by zidovudine is currently being studied.

Which were released and approved for sale in many countries of the world, as well as in Russia.
This drug has been used in medicine for more than ten years. Thanks to its wide application and numerous clinical experiences, the absolute safety of Elcar has been proven. The drug received particular popularity and wide opportunities for use in such branches of medicine: pediatrics, neurology, cardiology, endocrinology, gastroenterology, and sports medicine.
Producer: the manufacturer of Elkar is the pharmacological company PIK-PHARMA, Russia.

Active substance: the main active ingredient in the preparation is

Elcar: dosage form and composition

Elkar is prescribed as a solution for oral administration. 1 ml of the drug includes:
Active substance - levocarnitine (carnifit) - 300 mg and excipients:
Citric acid monohydrate 1.2 mg - cleanses the body of carcinogens, removes toxins and salts of heavy metals, has a tonic effect;
methyl parahydroxybenzoate 0.5 mg - has antiseptic properties, increases the shelf life of the drug;
propyl parahydroxybenzoate 0.2 mg - a preservative, allows the drug to last longer;
purified water up to 1 ml.

Elcar testimony

In complex therapy, Elkar is prescribed for such conditions:
- to improve performance in case of excessive physical and mental overload, as well as to increase endurance, reduce fatigue, especially in the elderly;

During the recovery period of the body after operations, injuries, as well as to accelerate the healing of tissues;

As part of complex therapy for the treatment of chronic gastritis with low acidity, as well as chronic pancreatitis;

As part of complex therapy in the treatment of diseases of the skin (psoriasis, seborrheic dermatitis, focal scleroderma, lupus erythematosus);

mild hyperthyroidism;

Neurological disorders in brain lesions (vascular, traumatic, toxic);

With anorexia syndrome on a nervous basis;

In diseases that are accompanied by a lack of carnitine or its increased loss (with myopathies, cardiomyopathies, mitochondrial diseases, some hereditary diseases). To compensate for the lack of carnitine in the human body;

With intense physical exertion for people who play sports;

For a rapid increase in muscle mass during a period of enhanced physical training;

To accelerate rehabilitation after physical overload;

With muscle injuries, for speedy rehabilitation.

Why Elcar for newborns and children

This drug is widely used in pediatrics for the treatment of newborns and children under 3 years of age. Under the strict supervision of a doctor, Elkar is prescribed for such conditions: nursing premature babies, newborns with trauma during childbirth or suffocation, children with a weak sucking reflex and poor weight gain, infants with reduced muscle tone. Also, the drug is widely used to treat children with insufficient development of motor reflexes and mental disorders.
Elkar is prescribed for the treatment of children who are at risk, as well as for low body weight in adolescents under 16 years of age.
Due to the fact that L-carnitine is an analogue of human carnitine, which is produced by the body, the drug helps to increase the protective forces of the immune system, improves metabolism and overall energy metabolism.

Children more than adults need additional intake
L-carnitine, since the absorption of this substance is only 12%, which is much less than the daily requirement. That is why Elkar is recommended for children from the first days of life.
L-carnitine is found in breast milk, and if the mother is breastfeeding, then the daily need for this substance is fully satisfied. However, very often a woman's lactation is disturbed, and she stops breastfeeding a child in the first months of his life. Insufficient intake of L-carnitine in the body of a child leads to a violation of important functions of its development, immunity decreases, and there is a tendency to become infected with various diseases.
In addition to immune-boosting drugs, children need additional sources of L-carnitine to ensure proper development and growth.
The need for L-carnitine increases significantly during periods of intense physical activity, as well as with colds and viral diseases. Parents who care about their child choose L-carnitine to strengthen the baby's immune defenses.

Use during pregnancy and lactation

Studies regarding the safety of the drug during pregnancy and lactation have not been conducted, so the use of Elkar is not recommended.

Side effects

When taking the drug, allergic manifestations on the skin, pain in the stomach, dyspeptic symptoms and myasthenia gravis are possible.

The use of Elkar and the dosage of the drug

The drug is prescribed in combination with other drugs inside, half an hour before meals, diluted in a small amount of water.
With excessive physical and psychological stress - starting from 0.75 g (half a measuring spoon or 2.5 ml) three times a day, or 2.25 g (one and a half measuring spoons, or 7.5 ml) 2-3 times a day ;
With anorexia due to nerves or during the recovery period of the body after surgery, injuries - 1.5 g (1 scoop or 5 ml) twice a day. The course of therapy is 1-2 months;
In the complex in the treatment of chronic forms of gastritis or chronic pancreatitis with reduced secretions - 0.375 g (a quarter of a measuring spoon or 1.25 ml) twice a day. The course of therapy is 1-1.5 months.
In the treatment of diseases of the skin - 0.75 g (half a measuring spoon or 2.5 ml). The course of therapy is 2-4 weeks.
In the treatment of mild hyperthyroidism, 0.25 g (13 drops) twice a day. The course of therapy is 20 days. Repeatedly the drug is prescribed 1-2 months after the previous dose, or for 3 months without a break.
For vascular, traumatic and toxic lesions of the brain, 0.75 g (half a measuring spoon or 2.5 ml) 1 time per day. The course of therapy is up to 5 days. If necessary, the treatment is repeated after 2 weeks.
In diseases that occur against the background of a lack of carnitine (primary and secondary forms of carnitine deficiency) - up to 50-100 mg / kg (2-5 drops per kg) 2 to 3 times a day. The course of therapy is 3-4 months.

As a rule, children are prescribed this drug as an additive to sweet drinks (jelly, compote, juice). For children who are under 3 years old, only the doctor determines the dosage.
Dosage according to age:
3-6 years 0.1 g once (5 drops) twice a day. The daily dose is 0.2-0.3 g (11-16 drops), the course of therapy is more than 1 month;
6-12 years 0.2-0.3 g one-time (11-16 drops) twice a day. The daily dose is 0.4-0.9 g (22-48 drops), the course of therapy is at least 1 month;

With growth retardation, 0.25 g (13 drops) twice a day, the course of therapy is 20 days. If necessary, the treatment is repeated 1-2 months after the previous dose, or prescribed for 3 months without interruption.
With intense physical exertion in sports, 2.5 g is prescribed 1-3 times a day. The daily dose is 2.5-7.5 g. If Elkar is prescribed for therapeutic purposes, then the dose is 70-100 mg / kg per day (5-7.5 g per day). The course of therapy is 3-4 weeks before sports competitions. During the period of enhanced training, the drug is taken for 1.5-2 months.

Elcar Reviews

The drug quickly gained popularity among consumers as a wonderful versatile, and most importantly - an effective tool. It is widely used in pediatrics, in the future - its wider use by an adult audience.

Elcar: price

The price of a 25 ml oral drug in a vial is about 290 rubles, the price for a similar 50 ml drug is already much more profitable - about 330 rubles, which once again confirms the share of the cost of packaging in the price of many products. The cost of a bottle of the drug for oral administration with a volume of 100 ml is more than 500 rubles, and the drug in ampoules costs about 350 rubles.

Elkar is a drug with a metabolic effect with the active ingredient levocarnitine, produced by the pharmaceutical company Pik-Pharma. Produced in the form of an injection solution, it is used intramuscularly and intravenously. Outwardly, it is a clear, colorless liquid, contains 100 mg of the active substance (levocarnitine or carnifite) per 1 ml. Prepared on the basis - water for injection. Release form - 5 ml ampoules, ampoules contain a break point or line for more convenient use.

Pharmacologically, Elkar is intended for the correction of metabolic processes. L-carnitine is involved in metabolic processes as a transporter of fatty acids through the cell membrane from the cytoplasm to the mitochondria, it is in the mitochondria that these acids are converted by beta-oxidation with the release of energy in the form of ATP.

Due to its action, L-carnitine increases the tolerance of the nervous tissue to negative external and internal factors (hypoxia, traumatic influences, intoxication, etc.), inhibits the synthesis of keto acids and the processes of anaerobic glycolysis, thereby reducing the degree of lactic acidosis. Elkar normalizes the acid-base composition of the blood, leads to the restoration of the processes of self-regulation of cerebral hemodynamics and normalization of blood circulation in the affected area, accelerates the recovery processes in the lesion, is a good and safe anabolic.

Pharmacokinetically, Elcar after intravenous administration is almost completely eliminated from the blood after three hours. It freely penetrates into the liver and heart tissues, more slowly into the muscles. It is excreted by the kidneys, mostly in the form of acyl esters (the main metabolite of Elkar).

Indications

Elcar is used in complex therapy in case of stroke (ischemic stroke, transient ischemic attack, etc.). Elcar is prescribed in all periods of cerebrovascular accidents. It is also used for the consequences of trauma and toxic brain damage.

It can be used as a restorative agent in the recovery period after neurosurgical interventions. Elcar is indicated for carnitine deficiency (both primary and secondary), including in patients with chronic renal failure undergoing hemodialysis.

It can be used for cardiomyopathies, coronary artery disease (angina pectoris, myocardial infarction, postinfarction cardiosclerosis), circulatory disorders due to cardiogenic shock, as well as other metabolic disorders in the myocardium.

Contraindications

Elcar is contraindicated in case of individual intolerance. Not applicable during lactation and during pregnancy.

Mode of application

One ampoule contains 500 mg of L-carnitine. Elkar is used intravenously by drip or jet (administration time 2-3 minutes) or intramuscularly. Immediately before the drip, the Elcar ampoule is dissolved in 200 ml of saline or a 5% glucose solution.

In cases of stroke, Elkar is prescribed at a dosage of 1 gram per day (2 ampoules) for the first 3 days, then therapy continues at a dose of 0.5 grams per day (1 ampoule) for a week. After 2 weeks, repeated courses of therapy lasting 3-5 days are acceptable.

When using Elcar in the subacute and recovery periods of a stroke, with dyscirculatory encephalopathy, with other brain lesions, as well as deficient conditions on the part of carnitine, Elcar solution is administered to patients at the rate of 1-2 ampoules per day for a week. If necessary, repeat the course after 2 weeks.

Intravenous administration is used for secondary carnitine deficiency, which is formed during regular hemodialysis. Dose - 2 grams once (after each procedure). In acute myocardial infarction, Elkar is used at a dose of 3-5 grams per day, divided into 2-3 doses in the first 2 days, then the dose is reduced to 1-2 grams; in case of cardiogenic shock, the dosage is 3-5 grams per day, divided into 2-3 doses until the patient exits the state of shock. After leaving the acute state, they switch to oral administration of Elcar

Side effects

Allergic reactions may develop. There is a possibility of muscle weakness (primarily in patients with uremia). With rapid administration (more than 90 drops per minute), pain may develop along the course of the vein, decreasing with a decrease in the rate of administration.

Overdose

There are no cases of overdose in the scientific literature.

special instructions

Glucocorticosteroids contribute to the accumulation of Elkar in tissues (except the liver), other anabolics enhance the existing effect of the drug.

Storage conditions

Elcar is stored in a cool, dark place at temperatures up to 25 °C. Shelf life 3 years.

Analogues

An analogue of the drug Elkar in injectable form is the drug Karniten.

Price

Elcar in injectable form is a prescription drug. The average prices for ampoules of 5 ml per pack of 10 ampoules are 370-420 rubles.

You should not prescribe medications for yourself. Before using Elcar in injectable form, consult a doctor!

Elcar 30 represents a group of one-component products. The main purpose of the drug is the normalization of metabolism. Thanks to him, the resistance of the nervous tissue to negative factors increases. At the same time, the blood supply to the organs is restored. The drug stands out from the background of analogues due to the minimum number of restrictions, side effects.

1 Registration number and ATX

LSR-006143/10

2 Name

Trade: Elkar.

Latin: Elcar.

INN: Levocarnitine.

3 Indications for use

The drug is advisable to use in the following cases:

• the need to improve performance (mental and physical);
• intense psycho-emotional stress;
• elimination of such a symptom as rapid fatigue;
• activation of tissue regeneration processes after surgery, traumas of varying severity;
• elimination of negative manifestations, and sometimes the causes of gastritis, chronic pancreatitis, provided that in these cases there is a violation of secretion production, the drug can only be used as part of complex therapy;
• treatment of pathological conditions with manifestations on the external integument: psoriasis, eczema, scleroderma, lupus erythematosus;
• anorexic disorders of a nervous nature;
• disruption of the brain of various etiologies (vascular, traumatic, toxic nature), contributing to the development of neuralgia;
• deficiency of carnitine or its rapid loss by the body, which can be the cause of various pathologies, disruption of the work of various organs and systems;
• for the prevention of athletes, in this case Elkar is used as a source of trace elements and vitamins, helps to maintain the musculoskeletal system, improve speed and strength, reduce fat and increase muscle mass;
• weight loss, provided that the drug is used in combination with other measures: a properly composed diet, sufficient physical activity.

4 Pharmacological action

The main task of the drug in therapy is the normalization of metabolic processes. Levocarnitine in the composition (or L-carnitine) is a substance of natural origin. It is often confused with B vitamins, however, the main component in Elcar has only a similar mechanism of action. Levocarnitine is produced by the human body. To a greater extent accumulates in the tissues of striated muscles, liver.

Thanks to this component, the activity of coenzyme A is maintained. Levocarnitine transforms long-chain fatty acids into the mitochondrial matrix. Violation of its synthesis occurs with a deficiency of certain nutrients. This is due to the fact that the process of production of L-carnitine is supported with the participation of vitamin C, group B, iron, methionine, lysine, and a number of enzymes. Also, its synthesis slows down due to the development of genetic disorders, as a result of severe kidney damage, with antibiotic therapy.

Considering that in childhood, levocarnitine is supplied to the body with food to a greater extent, since it is produced naturally in small quantities (12% of adult concentration), it is recommended to provide high-quality nutrition. The main source of carnitine are animal products (milk, cottage cheese, meat).

Pharmacodynamics is based on supporting the transformation of fats into energy. Carnitine is involved in the last step of this process. With its participation, the oxidation of fatty acids is carried out, the production of ATP in mitochondria. Without carnitine, the delivery of fatty acids to the mitochondria is disrupted.

Thanks to the support of the function of coenzyme A, the activation of carboxyl-containing metabolites is noted. As a result, levocarnitine is included in metabolic processes, participates in various biochemical reactions.

For example, it supports the removal of short-chain fatty acids from the mitochondria, which contributes to the release of intramitochondrial coenzyme A. This stage is the most important in the process of optimizing metabolic catabolism.

Levocarnitine inhibits the production of ceramides, due to which the protective function of the substance manifests itself in controlled cell death. In addition, this component in the composition of Elcar exhibits a neuroprotective effect when methamphetamine is administered, since it prevents metabolic disorders, which could lead to energy loss. Other properties of carnitine:

• helps to reduce excess body weight;
• normalizes the content of fat in muscles;
• replenishes glycogen deficiency in soft tissues, liver;
• participates in the process of restoring the structure of nerve tissues.

Based on a number of studies, an opinion was formed that the drug is able to alleviate the patient's condition in chronic ischemia (while reducing the area of ​​tissue damage). With exacerbation of the symptoms of this pathological condition, on the contrary, there is a decrease in the effectiveness of the drug, which is due to a decrease in its concentration and a weakening of the protective effect on the body during apoptosis processes.

Pharmacokinetics: while taking drops orally, rapid absorption is noted, the drug begins to act after 3 hours (peak activity of levocarnitine). The achieved therapeutic effect is maintained for the next 9 hours. It is permissible to administer the medicinal substance intramuscularly (injection solution), then carnitine is retained in the blood for 4 hours, and when administered intravenously, after 3 hours, no traces of the compound remain in the plasma.

5 Composition and form of release

The active substance is levocarnitine. In the designation of the agent in question, its concentration is encrypted - 30%. 1 ml of liquid medicine contains 300 mg of levocarnitine. In this amount, the active ingredient is part of the oral solution. Other substances that do not show metabolic activity:

• citric acid monohydrate;
• methyl parahydroxybenzoate;
• propyl parahydroxybenzoate;
• purified water.

You can buy the drug in this form in a 100 ml bottle.

6 How to take Elcar 30 correctly?

The treatment regimen differs for most pathological conditions in which it is permissible to use this remedy.

Dosage

Instructions for the use of various violations:

• excessive physical or psycho-emotional stress: 2.5-7.5 ml of solution, with the minimum dose prescribed 3 times a day, and the maximum amount (7.5 ml) taken 2-3 times a day;
• in case of anorexic disorders of a nervous nature, as well as during the recovery period after injuries or operations, treatment is carried out according to a single scheme: 5 ml twice a day, the course lasts no longer than 2 months;
• as part of complex therapy for chronic gastritis and pancreatitis: 1.25 ml 2 times a day, duration of treatment - up to 1.5 months;
• skin diseases: 2.5 ml per day, duration of therapy - no more than 4 weeks;
• violation of cerebral circulation: 2.5 ml per day, the duration of the course of treatment is up to 4 days;
• in order to compensate for the deficiency of carnitine in the body, 2-5 drops / kg of body weight are prescribed, the frequency of taking such a dose is 3 times a day, the course of therapy cannot last longer than 4 months.

Before meals or after?

To achieve the desired results of treatment, it is recommended to take the solution half an hour before meals. The drug should be taken with water.

Application duration

The duration of the course of treatment depends on the type of pathological condition and can vary from 3 days to 4 months.

7 Features of the use of Elkar 30

When treating children under 3 years of age, medical supervision is necessary.

Pregnancy and lactation

Due to the lack of data on the degree of negative effect of levocarnitine on the fetus, the agent in question is not prescribed during the gestation period. When breastfeeding, it is not used for the same reason.

Childhood

The drug is approved for use in the treatment of patients under 18 years of age. There are no age restrictions. For patients under 16 years of age, Elkar is prescribed to correct growth disorders, with a lack of body weight. It is permissible to use this remedy for the restoration of newborns, the treatment of children up to a year in a number of cases:

• insufficient weight gain;
• movement disorders;
• weak sucking reflex;
• therapy for infants who suffer birth trauma or breath holding.

Dosage in violation of growth: 13 drops 2-3 times a day. The duration of treatment is 20 days, then take a break for 1-2 months and resume therapy. For other disorders, the dose is determined taking into account age and can be 5-16 drops. The course of therapy in each case is 1 month.

Elderly age

It is allowed to use the drug for the treatment of patients in this group. The dosage is not adjusted.

8 Side effects

Negative reactions that can develop during therapy with this drug:

• violation of the digestive function;
• pain in the epigastric region;
• reduced muscle tone;
• allergies: itching, rash, redness of the skin.

Impact on vehicle control

The drug does not affect the reaction rate, the level of attentiveness. For this reason, it is allowed to drive a car during therapy.

9 Contraindications to the use of Elkar 30

The remedy is not used in case of a developing negative reaction of an individual nature.

10 Interaction with other drugs

Medications of the group of glucocorticosteroids help to slow down the process of excretion of a substance from the body, as a result, its accumulation in tissues is noted. However, this process bypasses the liver.