How to take omez before meals. Gelatin capsules "Omez D"

Omez (in Latin OMEZ) - antiulcer drug, the main active ingredient, which omeprazole has a restorative and stimulating effect on the walls of the stomach and duodenum. Also, the composition of the product includes such excipients as mannitol, lactose, sucrose, hypromellose and others. The form of release of the drug is different:

Tablets, coated with a fast-dissolving coating;
Capsules, highly soluble under the action of gastric juice;
Powder recommended before taking for dissolution in a certain amount of liquid;
Solution for injection - used intravenously;
special drops.

The manufacturer of the product is India, the Dr. Reddis company, more detailed information about which can be found on the online resource wikipedia.

Indications for the use of the drug Omez

Let's figure out why Omez is prescribed? Basically, the indications for the use of the drug are as follows:

stomach ulcer;
Gastritis (acute and chronic);
Erosion of the railway tract;
Oncological diseases;

Effectively, the medicine is used for heartburn, pancreatitis, with low acidity of the gastrointestinal tract. It is also indicated for the treatment of Zollinger-Ellison syndrome.

Omez: instructions for use

It is possible to take the drug correctly only as prescribed by the attending physicians and in accordance with the dosage indicated in the prescription. Omez is usually prescribed in a daily dose not exceeding 20 mg. For gastritis, stomach ulcers, heartburn, erosion, poisoning, oncology, it is better to drink it in the morning, in the morning before meals, a method different from this can only be prescribed by a specialist. The course of treatment is also determined by a doctor - a gastroenterologist or therapist, as a rule it is about 2 weeks (14 days). Alcohol during this period is strictly contraindicated.

When pregnant, how to take?

During pregnancy, the drug is clearly contraindicated, especially in the early stages. It should also not be used while breastfeeding.

With gastritis, take Omez before meals or after?

For gastritis and other diseases of the gastrointestinal tract, Omez capsules are indicated to be taken 20 hours before meals in the morning and after 2 hours after meals in the evening.

How long can Omez be taken without interruption? The course of treatment in time with this remedy is determined by the attending physician. And the question of how long you can take it without a break, the answer should be given by a specialist and expert in the medical field. Usually this continuous period does not exceed 14 days.

Analogues

Today, pharmacies offer the consumer all kinds of substitutes - analogues of the Indian remedy (in everyday life they are called synonyms), including the Swiss, German manufacturer, as well as the production of Russia. Domestic analogues, by the way, are very popular, since the composition differs slightly, and the cost is much lower, which plays an important role for the local consumer. Such drugs of this pharmacological group include copies from the list:

Ranitidine;
Losek Maps;
Ranitidine;
Nolpaza;
Omezol;
Ultop;
Ortanol;
Nexium;
Famotidine;
Emanera;
Controloc ;
Almagel;
Kwamatel;
Maalox;
Duspatalin;
Phosphalugel.

Finding analogues cheaper is not always the right decision, especially if the doctor himself prescribed a specific medication. The difference may seem insignificant to you, and the substitution in one or two components of the composition will be significant for the body. As for the price, you must immediately indicate the amount for which you can afford the treatment. And then the question related to cheaper drugs will not arise after you leave the specialist.

Omez or Omeprazole, which is better? Answering the question which is better Omez or Omeprazole, it should be noted that these drugs are almost identical. Omeprazole is an original medicine made in Russia, Omez is a generic drug from an Indian manufacturer with cheap auxiliary additives. Feedback from consumers on these two drugs are mostly positive.

Omez Insta- an antiulcer drug, a specific proton pump inhibitor: it inhibits the activity of H + / K + -ATPase in the parietal cells of the stomach, blocking the final stage of hydrochloric acid secretion, thereby reducing acid production.

Omeprazole is a prodrug and is activated in the acidic environment of the secretory tubules of the parietal cells of the stomach. The effect is dose-dependent and provides effective inhibition of both basal and stimulated acid secretion, regardless of the nature of the stimulating factor.

Elimination of heartburn after taking the drug occurs within 30 minutes. Inhibition of 50% of the maximum secretion of hydrochloric acid lasts 24 hours.

A single dose per day provides a quick and effective inhibition of day and night gastric secretion, reaching its maximum after 4 days of treatment and disappearing by the end of 3-4 days after the end of the dose.

In patients with duodenal ulcer, taking 20 mg of omeprazole maintains an intragastric pH above 3 for 17 hours.

Description of the drug Omez Insta is not intended for prescribing treatment without the participation of a doctor.

Pharmacokinetics

Absorption - high; the time to reach the maximum concentration (TCmax), on average, 30 minutes (10-90 minutes), bioavailability - 30-40% (with liver failure increases to almost 100%); having a high lipophilicity, it easily penetrates into the parietal cells of the stomach, the connection with plasma proteins is 95% (albumin and acid alpha1-glycoprotein). The half-life (T1 / 2) is about 0.5-1 hours (with liver failure - 3 hours); total plasma clearance - from 0.3 to 0.6 l / min. There is no change in T1 / 2 during treatment.

Almost completely metabolized in the liver with the participation of the cytochrome P450 (CYP) enzyme system, with the formation of six pharmacologically inactive metabolites (hydroxyomeprazole, sulfide and sulfonic derivatives, etc.). A significant part of the metabolism of omeprazole depends on the polymorphically expressed specific isoform of CYP2C19 (S-mephenytoin hydroxylase), which is responsible for the formation of hydroxyomeprazole, the main plasma metabolite. It is an inhibitor of the CYP2C19 isoenzyme. Excretion by the kidneys (70-80%) and bile (20-30%). In chronic renal failure, excretion decreases in proportion to the decrease in creatinine clearance. In elderly patients, excretion decreases, bioavailability increases.

Indications for use Omez Insta

and other symptoms associated with gastroesophageal reflux disease (GERD); non-erosive and erosive (reflux esophagitis) forms of GERD;
peptic ulcer of the stomach and duodenum (including prevention of recurrence);
eradication of Helicobacter pylori in infected patients with peptic ulcer of the stomach and duodenum (as part of combination therapy);
NSAID gastropathy;
hypersecretory conditions (Zollinger-Ellison syndrome, stress ulcers of the gastrointestinal tract, polyendocrine adenomatosis, systemic mastocytosis).

Dosage and administration

Inside, 30 minutes before meals.

Pour the contents of the sachet into a cup, add 1-2 tablespoons of water (do not use other liquids or food!), stir thoroughly until a homogeneous suspension is obtained and drink immediately. If necessary, you can drink a small amount of water. For quick relief of symptoms of heartburn, a single dose of 20 mg of the drug is sufficient.

Patients with non-erosive GERD - 20 mg 1 time / day. within 4 weeks.

Patients with erosive form of GERD (reflux esophagitis) - 20 mg 2 times / day. within 4-8 weeks, depending on the severity of the esophagitis.

For the prevention of exacerbation of reflux esophagitis - 20 mg / day, the duration of maintenance therapy is determined individually.

With exacerbation of gastric ulcer or duodenal ulcer, not associated with Helicobacter pylori - 20 mg in the morning 1 time / day. within 4-8 weeks.

For the eradication of Helicobacter pylori, therapy is used in various combinations:

within 7-14 days omeprazole 20 mg, amoxicillin 1 g, clarithromycin 500 mg - 2 times / day;
or omeprazole 20 mg, clarithromycin 500 mg, metronidazole 500 mg - 2 times / day;
or omeprazole 20 mg - 2 times / day, bismuth preparations at a dose of 120 mg - 4 times / day, metronidazole 500 mg - 3 times / day. and tetracycline 500 mg - 4 times / day.

For the prevention of gastric ulcer or duodenal ulcer - 20 mg in the morning 1 time / day. within 4-8 weeks.

For the treatment of NSAID-gastropathy - 20 mg 2 times / day. within 4-6 weeks, for prevention - 20 mg / day. for the period of NSAID use in patients with risk factors for the development of NSAID gastropathy.

In hypersecretory conditions - 20 mg in the morning 1 time / day. within 4-8 weeks.

In the treatment of Zollinger-Ellison syndrome, doses are selected individually, depending on the clinical condition. The recommended starting dose is 60 mg per day. In most patients, the condition is adequately controlled in the dose range of 20-120 mg. If it is necessary to use a dose of more than 80 mg, it is necessary to divide it into 2 injections.

In elderly patients and in renal insufficiency, there is no need to adjust the dose. In hepatic insufficiency, a daily dose of 20 mg may be sufficient.

Application features

Before starting therapy, it is necessary to exclude the presence of a malignant process (especially with a stomach ulcer), since treatment, masking the symptoms, may delay the correct diagnosis. Taking it with food does not affect its effectiveness. Omez® Insta does not affect the ability to drive vehicles and work with mechanisms. Due to the fact that dizziness and drowsiness may occur during therapy with Omez® Insta, care should be taken when driving vehicles and other mechanisms.

Side effects

In rare cases, the following, usually reversible adverse reactions may occur.

From the side of the hematopoietic organs:

rarely - leukopenia, thrombocytopenia;
very rarely - agranulocytosis, pancytopenia.

From the digestive system:

often - diarrhea or constipation, abdominal pain, nausea, vomiting, flatulence;
rarely - increased activity of "liver" enzymes, taste disturbances;
very rarely - dry mouth, stomatitis, candidiasis of the gastrointestinal mucosa;
in patients with previous severe liver disease - hepatitis (including jaundice);
very rarely - liver failure, incl. with the development of encephalopathy (in patients with a history of liver disease).

From the nervous system:

often - headache,
infrequently - dizziness, paresthesia, drowsiness,
rarely - a violation of taste.

Mental disorders:

infrequently - insomnia;
rarely - agitation, confusion, depression,
very rarely - aggression, hallucinations.

From the sense organs:

infrequently - vertigo;
rarely - blurred vision.

From the musculoskeletal system:

rarely - arthralgia, myalgia;
very rarely - muscle weakness.

From the side of the skin:

infrequently - dermatitis, itching, rash, urticaria;
rarely - alopecia, photosensitivity,
very rarely - erythema multiforme exudative, Stevens-Johnson syndrome, toxic epidermal necrolysis.

Allergic reactions: rarely - hypersensitivity reactions, including fever, angioedema and anaphylactic reactions (including anaphylactic shock).

From the genitourinary and reproductive system:

rarely - interstitial nephritis,
very rarely - gynecomastia.

Metabolic disorders:

rarely - hyponatremia,
very rarely - hypomagnesemia.

infrequently - malaise, peripheral edema,
rarely - bronchospasm, increased sweating.

Interaction with other drugs

Due to a decrease in the acidity of gastric juice during treatment with omeprazole, the absorption of other drugs (PM), the absorption mechanism of which depends on the pH of gastric juice, may decrease or increase. Reduces the absorption of ketoconazole and itraconazole. Increases the absorption of digoxin. The combined use of omeprazole at a dose of 20 mg 1 time per day and digoxin increases the bioavailability of digoxin by about 10%.

Omeprazole has been shown to interact with certain antiretroviral drugs. The mechanisms and clinical significance of these interactions are not always known. An increase in gastric pH during omeprazole therapy may affect the absorption of antiretroviral drugs. Interaction at the level of the CYP2C19 isoenzyme is also possible.

With the combined use of omeprazole and antiretroviral drugs, such as atazanavir and nelfinavir, during therapy with omeprazole, there is a decrease in their serum concentration. In this regard, the combined use of omeprazole with antiretroviral drugs such as atazanavir and nelfinavir is not recommended.

With the simultaneous use of omeprazole and saquinavir, an increase in the concentration of saquinavir in the blood serum was noted. Omeprazole inhibits CYP2C19, the main isoenzyme involved in its metabolism.

The combined use of omeprazole with other drugs, in the metabolism of which the CYP2C19 isoenzyme is involved, such as diazepam, phenytoin, warfarin, other vitamin K antagonists and cilostazol, can lead to a decrease in the metabolism of these drugs.

It is recommended to control the concentration of phenytoin in plasma while using phenytoin and omeprazole; in some cases, it may be necessary to reduce the dose of phenytoin. At the same time, in patients taking phenytoin for a long time, the combined use of omeprazole at a dose of 20 mg 1 time per day did not cause a change in the concentration of phenytoin in the blood plasma.

When using omeprazole in patients receiving warfarin or other vitamin K antagonists, monitoring of the international normalized ratio (INR) is necessary; in some cases, it may be necessary to reduce the dose of warfarin or other vitamin K antagonist. At the same time, in patients taking warfarin for a long time, the combined use of omeprazole at a dose of 20 mg 1 time per day did not cause a change in clotting time.

The use of omeprazole at a dose of 40 mg 1 time per day led to an increase in Cmax and area under the concentration-time curve (AUC) of cilostazol by 18% and 26%, respectively; for one of the active metabolites of cilostazol, the increase was 29% and 69%, respectively. Omeprazole does not affect the metabolism of drugs, the metabolism of which is carried out using the CYP3A4 isoenzyme, such as cyclosporine, lidocaine, quinidine, estradiol, erythromycin and budesonide.

With the simultaneous use of omeprazole and tacrolimus, an increase in the concentration of tacrolimus in the blood serum was noted. The CYP2C19 and CYP3A4 isoenzymes are involved in the metabolism of omeprazole. The combined use of omeprazole and inhibitors of CYP2C19 and CYP3A4 isoenzymes, such as clarithromycin and voriconazole, can lead to an increase in plasma concentrations of omeprazole by slowing down the metabolism of omeprazole.

The combined use of voriconazole and omeprazole resulted in a more than twofold increase in the AUC of omeprazole, which, however, did not require dose adjustment of omeprazole.

Drugs that induce CYP2C19 and CYP3A4 isoenzymes, such as rifampicin and St.

Contraindications

hypersensitivity,
fructose intolerance,
sucrase/isomaltase deficiency,
glucose-galactose malabsorption (due to the presence of sucrose in the preparation),
childhood,
pregnancy,
lactation period.

The drug should not be co-administered with atazanavir and nelfinavir. With caution - renal and / or liver failure.

Overdose

Symptoms:

headache,
dizziness,
lethargy,
confusion,
tachycardia,
arrhythmia,
blurred vision,
drowsiness,
dry mouth
nausea,
vomit,
flatulence.

Treatment: symptomatic. If necessary - gastric lavage, activated charcoal. Hemodialysis is not effective enough.

Questions and answers on the topic "Omez Insta"

Question:Hello! I was diagnosed with erosive gastritis. They prescribed Omez with antibiotics and Maalox. At the same time, maalox one hour before meals, then omez half an hour later. My question is: will Maalox interfere with the absorption of Omez?

Answer: Such a combination of drugs is acceptable and can be used if there are objective indications.

Question:Hello! In connection with a sore knee, the doctor prescribed me to drink Ketonal-duo, and also said to drink Omez so that there were no stomach problems. The question arose: if you need to drink Ketonal during or after a meal, and Omez before a meal, then what is the best way to take these pills? Before eating Omez, and after this Ketonal? Or First Ketonal, and before the next meal drink Omez?

Answer: Hello! Before meals - Omez, after meals - Ketonal.

Question:Hello, I am 30 years old. I have gastritis and inflammation of the duodenum 12, prolapse of the stomach of the second degree, I have lost a lot of weight. I was prescribed omez, and the therapist - Elkar, is it possible to combine these drugs?

Answer: You can combine these drugs. Pain in the stomach can be disturbing when lowered, so you need to restore body weight.

Recently, the group of medicines for the gastrointestinal tract has been constantly updated on the market of medications. But most patients prefer the well proven Omez to treat gastritis. The drug gently affects the body, preventing the negative effects of aggressive drugs, while perfectly relieving the symptoms of the disease.

The main active ingredient of the drug is omeprazole, the mass fraction of which is 20 mg.

Additional substances that make up the granules are mannitol, lactose, sodium lauryl sulfate, sodium hydrogen sulfate, etc.

The granules have an enteric coating consisting of methacrylic acid, sodium hydroxide, talc and titanium dioxide.

Release form

The drug Omez is available in two forms: in the form of a powder and in capsules. These two types differ in the amount of active substance. Capsules are also available with the addition of domperidone. This component improves the functioning of the peristalsis of the stomach.

Omez is a dragee placed in small capsules, size "2". The granules are white or slightly creamy in color. Gelatin capsules are absolutely transparent in appearance and are covered with a pink cap. Each part of the capsule is labeled "Omez" in black. Omez with Domperidone has a purple cap.

Capsules Omez 20 mg are located in 10 pieces per blister. 3 strips are placed in a cardboard box.

average price

Omez has a clear advantage over other antigastritis drugs. For its high performance, the drug has a fairly low price and is available to buyers with a low family budget.

Omez is widely represented in the pharmacy chain. The average cost of 10 mg capsules per blister in a cardboard box is 69 rubles.

Omez 20 mg No. 30 on three blisters in one box has an average price of 169 rubles.

The action of the drug

Omez (active ingredient Omeprazole) is a drug responsible for the level of acidity of gastric juice. The capsule contains a large number of small pills, which, after entering the stomach, begin to act after two hours. According to the attached instructions, one capsule will be enough to carry out the synthesis of hydrochloric acid with gastric juice. This interaction creates the necessary healthy environment for the normal functioning of all organs of the gastrointestinal tract. Auxiliary components of the drug affect the production of gastric juice and block its irritants.

Omez is a fairly safe drug, it is prescribed even to patients suffering from minor problems in the functioning of the kidneys and liver. The liver processes all the components of the medicine perfectly and naturally removes it from the body. Therefore, experts prescribe Omez for the treatment of gastritis with high acidity.

The main effect of Omez is the protection of the gastric mucosa. But its properties are not limited to this. After ingestion, the granules of the drug block the main symptoms of gastritis, such as heartburn, heaviness in the stomach, and belching. This becomes possible due to the antimicrobial properties of the drug, aimed at suppressing the pathogenic bacteria Helicobacter pylori.

Here are the main properties of Omez:

Reducing the negative impact of taking antibiotics;
No effect on the reaction rate, so taking Omez is allowed while driving;
It is well tolerated, so the course of taking Omez can be two months or more;
Has a powder form for the treatment of serious advanced diseases;
Excretion from the body in a short time;
Application for the prevention of gastric ulcer.

How to use

Reception of Omez, as well as any other drug, should be carried out only as prescribed by the attending physician, who will establish the dosage and regimen of administration. The instruction gives only general rules for the use of the medicine.

It is recommended to take Omez one capsule 20 mg once a day for fourteen days. To be effective, the medicine should be drunk in the morning on an empty stomach. The drug relieves painful symptoms in a short time, and the patient soon gets relief. It is permissible to change the treatment regimen, but only after consultation with a specialist.

As already mentioned, the treating substance is a granule placed in a capsule. During treatment, it must be swallowed without opening or chewing. Since the therapeutic effect will be optimal only if the capsule shell dissolves on its own in the stomach.

For the treatment of gastritis with high acidity, Omez is taken in the morning on an empty stomach for 14 days. The drug is also taken for preventive purposes. In this case, it is drunk before going to bed for three hours during the same two weeks.

With the development of a severe form of the disease, the doctor prescribes treatment using a powder for invasive administration. To prepare injections, it is necessary to prepare a vial with 100 ml of five percent glucose, take 5 ml from it and inject it into a vial with Omez powder. Mix everything thoroughly, draw the resulting solution back into the syringe and add it to a large vial of glucose. The solution for the dropper is ready. It is worth clarifying that use only a freshly prepared solution and inject into a vein for at least thirty minutes.

Omez D is prescribed for esophageal reflux, one capsule in the morning half an hour before meals and in the evening after dinner at 20.00. Omez D is good for heartburn and dyspepsia. But it is worth remembering that it is not recommended to take the drug with Domperidone in the treatment of gastritis caused by Helicobacter pylori bacteria, since antibiotics are taken for its treatment, and Domperidone inhibits its action.

Before meals or after?

Patients who are first prescribed Omez for the treatment of acute gastritis are wondering how to take it - before meals or after. There is a general rule for taking medications aimed at treating diseases of the gastrointestinal tract - this is taken before meals. The action of these drugs is aimed at preparing the gastric mucosa for eating by covering erosions and small ulcers with a protective film and reducing the secretion of hydrochloric acid.

Omez is the most effective medicine for the treatment of acute gastritis and is an effective drug for restoring the gastric mucosa. Therefore, it should be taken thirty minutes before meals. But it can also be taken after meals, only after two hours, when the contents of the stomach move into the intestines. In addition to the main treatment, Omez helps to get rid of the symptoms of gastritis - heartburn and heaviness in the stomach.

Omez for gastritis with high acidity

Omez is a drug that reduces the level of stomach acid, and belongs to the group of proton pump inhibitors, which are responsible for the activity of special glands located on the gastric mucosa. Omez inhibits the production of an enzyme - a proton pump, which is responsible for the production of hydrochloric acid. The components of the drug, getting into an acidic environment, reduce the production of hydrochloric acid. Due to this, the internal environment of the stomach acquires an alkaline basis, which makes it impossible for the development of pathogenic microorganisms.

Omez for gastritis with low acidity

As a rule, gastritis causes an increased production of hydrochloric acid, and the action of Omez is aimed at suppressing its secretion. But there are forms of gastritis, in which the production of an insufficient amount of hydrochloric acid is observed. At the same time, food stagnates in the stomach, its fermentation occurs. In this case, taking Omez is contraindicated, as it will aggravate the situation.

There is a form of gastritis in which Omez is prescribed. This is atrophic gastritis. The disease is characterized by a violation of the digestive process due to atrophy of the gastric mucosa. In this case, Omez reduces the level of acid exposure to epithelial damage. For the treatment of atrophic gastritis, Omez is not a single drug, but is included in a complex of drugs, among which enzymes are necessarily present to improve the functioning of the gastrointestinal tract.

Also, Omez is prescribed if the cause of gastritis is Helicobacter pylori bacteria. For their comfortable development, an acidic environment is necessary, and Omez, by lowering the production of acid, makes it impossible for the development of pathogenic microorganisms.

In the case of fasting food in the stomach and ejecting it into the lower esophagus, the hydrochloric acid in the food causes irritation in the form of heartburn. Omez in such a situation reduces the production of gastric juice and, thereby, relieves heartburn, and also prevents the development of pathologies of the esophagus.

Omez and De-Nol at the same time

Inflammation of the gastric mucosa is often accompanied by painful symptoms such as nausea, vomiting, heaviness, and discomfort. The patient's condition worsens if Helicobacter pylori bacteria are involved in the inflammatory process. Therefore, the doctor prescribes a complex treatment, which includes Omez and De Nol. The first affects the production of hydrochloric acid, reducing its amount, De Nol stops pathogenic bacteria by reacting with hydrochloric acid and creating a protective film. This film helps to speed up the healing process of gastric erosions, which prevents the occurrence of ulcers.

Many believe that these two drugs have the same effect. But this is an erroneous opinion. They complement each other and enhance the healing effect.

It is important to remember that with the simultaneous use of drugs, it is necessary to observe an interval between their doses of at least an hour. The fact is that De Nol, reacting with hydrochloric acid, reduces the effect of Omez. Therefore, the intake of these drugs must be diluted in time.

What is better Omez, De Nol or Omeprazole for gastritis?

These drugs are aimed at combating gastritis with high acidity. Although they have a similar principle of operation, there are still some differences.

Omez and Omeprazole have the same therapeutic effect, the difference is represented by additional components. Omeprazole has the maximum amount of active ingredient, Omez has much less of it, but the excipients that make up its composition reduce the likelihood of side effects. In addition, Omeprazole has a lower price.

Omez and De Nol also have a similar principle of action and the same mass fraction of the active substance, but De Nol contains bismuth subcitrate in its composition.

Indications for use

Omez is taken for gastritis both for treatment and for the prevention of the disease in adults. Also, the drug is prescribed as part of the complex treatment of various diseases of the gastrointestinal tract.

The main indications for taking Omez:

For the treatment or prevention of gastritis with high acidity;
Ulcer of the stomach and duodenum;
Dyspepsia of the stomach;
Inflammation of the pancreas;
To prevent reflux of stomach contents into the esophagus.

Side effects

The impact of the active substance on the work of the cell center can cause irritation and a decrease in the secretion of gastric juice and manifests itself in the form of the following side effects:

If side effects occur while taking the drug, then it is necessary to stop taking the drug or replace it with a similar one with a weaker effect.

After completion of the course of treatment, it is imperative to constantly monitor the state of health. For prophylactic purposes, it is good to take Omez twice a year at the dosage prescribed by the attending physician.

Contraindications

Omez is a rather gentle medicine and its use does not have any negative consequences for the body. But like any pharmacological drug, Omez has a number of contraindications:

Children's age up to 12 years;
The period of bearing a child and lactation;
Individual intolerance to the components of the drug, causing allergic reactions of the body;
Functional disorders of the urinary system;
Gastritis with reduced secretion of hydrochloric acid;
atrophic gastritis;
Threat of gastric or intestinal bleeding.

The active substance accumulates in the tissues of the body, and it is its increased concentration that can cause side effects. Therefore, without special indications, it is unacceptable to increase the dosage or course of treatment.

Cheap analogues

The drug Omez belongs to the budget group of products, but it also has a number of cheap analogues. This:

What is gastritis

Gastritis is a disease of a modern business person. Due to the constant lack of time for proper nutrition, the lack of liquid food, inflammatory processes occur on the gastric mucosa. There are several causes of the disease:

Throwing of food debris or bile from the stomach into the esophagus;
Pathogenic bacteria Helicobacter pylori. Excessive development of pathogenic microorganisms leads to damage to the gastric mucosa;
Nervous tension and constant stress often lead to disruption of the functioning of the digestive system;
Violation of the regime of the day, especially in people working on the night shift;
Unsystematic treatment with nonsteroidal drugs that have an aggressive effect on the gastric mucosa.

In all these cases, as a result of inflammation, the secretion of hydrochloric acid increases. Excess gastric juice acts on the foci of inflammation, corroding the epithelium of the protective layer of the stomach deeper and deeper. Increased acidity is the main cause of gastritis.

The antiulcer drug fights gastritis and prevents the development of peptic ulcer. The drug perfectly relieves the symptoms of pathology, while not having a negative effect on the body. Many doctors and patients recommend buying exactly the medicine. Omez (instructions for use for gastritis are below) - belongs to a new group of drugs that reduce the acidity of gastric juice, controlling its synthesis and hydrochloric acid.

When is the medicine indicated?

A unique remedy helps with many diseases of the gastrointestinal tract. Indications for the use of the drug Omez:

tumor of the islet apparatus of the pancreas;
peptic ulcer, which appeared as a side effect after the use of non-steroidal anti-inflammatory drugs;
inflammatory process occurring in the pancreas;
cutaneous-visceral mastocytosis (multiplication of mast cells and their infiltration in the internal organs);
GERD is an inflammatory process that occurs in the walls of the lower esophagus;
gastritis with high acidity;
pathological reflux of stomach contents into the esophagus.

What else is he needed for? The drug is prescribed for erosive and ulcerative disease of the stomach and duodenum, provoked by a bacterial infection of Helicobacter pylori.

Dosing regimen and scheme of application

Before and after using the drug, the victim must undergo an endoscopic examination to exclude the development of a malignant tumor in the stomach. Instructions - how to apply the medicine:

For pain in the stomach, the drug is taken 2 times a day, 1 capsule. Treatment lasts 7 days. Then you need to switch to taking the medicine 1 time per day. Drink 10 days.
When diagnosed with acute gastritis, Omez is drunk 2 times a day: in the morning 20 minutes before a meal, in the evening two hours after a meal. After the evening medication from dinner, it is advisable to abstain. The duration of therapy is 2 months.
Chronic gastritis is treated with this drug for 4 months. The drug is taken according to the following scheme: the dosage of the active substance is 20 mg per day, that is, 1 capsule.

For diseases such as gastritis, prophylaxis should be carried out annually. The disease worsens in spring and autumn. Therefore, taking the drug for prophylactic purposes begins in February or August. Application for gastritis for each patient is prescribed individually, but the general course of treatment should not be less than a month.

Important! Even when the disease does not bother you need to take the medicine until the end of the month. This is a treatment, therefore, for best effectiveness, you must complete the full course of Omez.

Before meals or after taking medicine? We have already mentioned this above, the remedy is drunk in the morning before meals, and in the evening after.

Application of Omez to children

How to give to children and is it possible? Gastroenterologists do not recommend giving medicine to crumbs under two years of age. Treatment of gastritis in babies is possible with the help of Omez. many prescribe the drug to 2-year-old babies, others are of the opinion that the medicine should not be given to children under 4 years of age.

Attention! The medication can be given to children after consulting a doctor. In order to avoid side effects, it is better that the dosage of the medicine is prescribed by an experienced doctor.

The instructions say that the drug is prohibited for children whose weight is less than 20 kg, but modern doctors simply reduce the dose for babies with less weight. Usually prescribed in powder form of the drug, it can also be given in capsules. The powder for the preparation of the suspension is poured into a cup, diluted with 2 tbsp. l. warm water and let the child drink. The capsule should not be mixed with anything (mashed potatoes, water, juices), otherwise the medicine will be ineffective.

Therapy of gastritis with Omez should not exceed two months. Method of application for children by age:

from 2 years, 1 capsule (20 mg) per day;
after 4 years, 20 mg in combination with other drugs.

After taking the capsule, the child should drink plenty of water.

Contraindications to the use of the drug

The drug Omez, among other things, has a small range of contraindications. The drug should not be taken with increased sensitivity to the drug. Omez tablets are strictly forbidden to be taken in any trimester of childbearing, while breastfeeding.

The drug is contraindicated if there is a risk of gastrointestinal bleeding, with pituitary adenoma, mechanical obstruction of the intestines and stomach. Also, the drug is undesirable to take with perforation of the intestines and stomach.

You cannot start using Omez on your own without consulting a doctor if you have been using nutritional supplements, dietary supplements, antifungal agents, diuretics, cardiotonic and antiplatelet drugs, medicines for the treatment of AIDS and HIV, antixiolytic and antiepileptic drugs for about 5 days.

Side effects of Omez

Those who have tried the medicine claim that it is well tolerated, however, the instructions for use for children and adults say the occurrence of side effects. Angioedema with urticaria, impaired bronchial patency, accumulation of fluid in the intercellular space - all this is an allergic reaction to one of the components of the drug.

In rare cases, taking the medication is accompanied by diarrhea or diarrhea, increased gas formation, severe stabbing pain in the abdomen, dry mouth, stomatitis, nausea and vomiting. Also, the use of the drug helps to reduce the level of leukocytes, their decrease in the total cellular composition of the blood; severe pathological condition of the blood, in which there is a decrease in all the enzyme elements of the blood. According to the instructions, reversible side effects most often appear in the form of:

pathological partial or complete hair loss;
anaphylactic shock;
thrombocypenia;
inability to sleep at night;
excitement and depression.

On the part of the digestive organs, there is also a transient increase in the level of liver enzymes in the blood, a violation of its functions. Perhaps the appearance of arthralgia, myalgia and muscle weakness.

Medication cost

The drug Omez is available in every pharmacy in Russia. The price of the drug directly depends on the number of capsules or tablets, the form produced and the selling pharmacy. For example, capsules 40 mg 28 pcs. cost 295 rubles, and powder 20 mg No. 5 - 81 rubles.

What can replace Omez?

If for some reason this medicine does not fit, it is replaced with an analogue. Before replacing the drug, you should consult with your doctor. Omez analogs: Omeprazole, Famotidine, Alumag, Pariet, Ulsepan, Parastamik, Loseprazol, Magnagel, Omeprazole-vocate, Peptipak, Zolopent, Ezokar, Rabeprazole, Famo, Dalargin, Escape, Omegast, Pantap, Lansobel, Ulcavis, Ontime, Omeprazole-akri , Novobismol.

Self-administration of drugs and the appointment of dosage is strictly prohibited. But, if this happens, carefully read the instructions for use, paying special attention to the block with contraindications and side effects.

In this article, you can read the instructions for using the drug Omez. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Omez in their practice are presented. We kindly ask you to actively add your reviews about the drug: the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Omez in the presence of existing structural analogues. Use for the treatment of peptic ulcer of the stomach and duodenum, as well as erosive and ulcerative lesions of the digestive tract in adults, children, as well as during pregnancy and lactation. Types of the drug Omez D and Insta and their difference from the original Omez.

Omez- antiulcer drug. Omeprazole (the active substance of the drug Omez) inhibits the enzyme H + -K + -ATPase (proton pump) in the parietal cells of the stomach and thereby blocks the final stage of hydrochloric acid synthesis. This leads to a decrease in the level of basal and stimulated secretion, regardless of the nature of the stimulus.

After a single dose of the drug inside, the effect of omeprazole occurs within the first hour and lasts for 24 hours, the maximum effect is achieved after 2 hours. In patients with duodenal ulcer, taking omeprazole at a dose of 20 mg maintains an intragastric pH of 3 units. within 17 hours. After discontinuation of the drug, secretory activity is completely restored after 3-5

Pharmacokinetics

Omez is rapidly absorbed from the gastrointestinal tract. Omeprazole is almost completely metabolized in the liver. It is excreted mainly by the kidneys in the form of metabolites.

Indications

peptic ulcer of the stomach and duodenum;
reflux esophagitis;
erosive and ulcerative lesions of the stomach and duodenum associated with the use of NSAIDs, stress ulcers;
erosive and ulcerative lesions of the stomach and duodenum associated with Helicobacter pylori (as part of complex therapy);
Zollinger-Ellison syndrome.

Release form

There is an erroneous opinion that there is such a form of release of the drug Omez as tablets, we hasten to upset, and maybe please - it is produced in all forms, except for tablets.

Capsules, soluble in the intestine 10, 20 and 40 mg.

Omez D, in addition to omeprazole, also contains domperidone, which enhances intestinal motility and promotes digestion. In capsules of 20 mg.

Omez Insta is a powder for oral suspension, with a pleasant smell, very suitable for children.

Instructions for use

It is taken orally with a small amount of water; the contents of the capsule should not be chewed.

Peptic ulcer of the duodenum in the acute phase: 20 mg (1 caps.) per day for 2-4 weeks, in resistant cases - up to 40 mg (2 caps.) per day.

Peptic ulcer of the stomach in the acute phase and erosive and ulcerative esophagitis: 20-40 mg (1-2 capsules) per day for 4-8 weeks.

Erosive and ulcerative lesions of the gastrointestinal tract caused by taking NSAIDs: 20 mg (1 capsule) per day for 4-8 weeks.

Eradication of Helicobacter pylori: 20 mg (1 caps.) 2 times a day for 7 days in combination with antibacterial agents.

Anti-relapse treatment of peptic ulcer of the stomach and duodenum: 20 mg (1 caps.) per day.

Anti-relapse treatment of reflux esophagitis: 20 mg (1 caps.) per day for a long time (up to 6 months).

Zollinger-Ellison syndrome: the dose is selected individually depending on the initial level of gastric secretion, usually starting with 60 mg per day. If necessary, the dose is increased to 80-120 mg per day, in which case it is divided into 2 doses.

Omez D

It is taken orally with a small amount of water, 1 capsule 2 times a day, 15-20 minutes before meals.

Omez Insta

The drug should be taken orally 30 minutes before meals. Pour the contents of the sachet into a cup, add 1-2 tablespoons of water (do not use other liquids or foods), mix thoroughly until a homogeneous suspension is obtained and drink immediately. If necessary, you can drink a small amount of water.

For quick relief of symptoms of heartburn, a single dose of the drug at a dose of 20 mg is sufficient.

Side effect

diarrhea or constipation;
nausea, vomiting, flatulence;
abdominal pain;
dry mouth;
taste disorders;
stomatitis;
hepatitis (including with jaundice);
headache, dizziness;
agitation, drowsiness, insomnia;
paresthesia;
depression;
hallucinations;
muscle weakness;
myalgia, arthralgia;
leukopenia, thrombocytopenia;
agranulocytosis, pancytopenia;
itching, urticaria, angioedema;
bronchospasm;
anaphylactic shock;
visual impairment;
peripheral edema;
increased sweating.

Adverse reactions are rare and are reversible.

Contraindications

childhood;
pregnancy;
lactation period;
hypersensitivity to the drug.

Use during pregnancy and lactation

The drug is contraindicated for use during pregnancy and lactation.

special instructions

Before starting therapy, it is necessary to exclude the presence of a malignant process (especially with gastric ulcer), since treatment, masking symptoms, may delay the correct diagnosis.

Taking the drug simultaneously with food does not affect its effectiveness.

In patients with severe hepatic insufficiency, the daily dose should not exceed 20 mg.

drug interaction

Long-term use of Omez at a dose of 20 mg 1 time per day in combination with caffeine, theophylline, piroxicam, diclofenac, naproxen, metoprolol, propranolol, ethanol, cyclosporine, lidocaine, quinidine and estradiol did not lead to a change in their plasma concentrations.

There was no interaction with concomitantly taken antacids. Changes the bioavailability of any drug whose absorption depends on the pH value (for example, iron salts).

Analogues of the drug Omez

Structural analogues for the active substance:

Gastrozole;
Demeprazole;
Zhelkizol;
Zerocide;
Losek;
Omezol;
Omecaps;
Omeprazole;
Omeprus;
Omephez;
Omizak;
Omipiks;
Omitox;
Ortanol;
Ocid;
Pepticum;
Petipak;
Promez;
Romesek;
Ulzol;
Ulkozol;
Ultop;
Helicide;
Helol;
Cisagast.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.