Valocordin calms. Indications for use

Valocordin: composition, properties, indications and contraindications, application features

The accelerated pace of life of a modern person, the wrong daily routine, constant nervous overload, psycho-emotional stress and irregular nutrition quite often lead to unpleasant symptoms from the central and autonomic nervous system.

Ignoring functional disorders due to lack of time for a visit to the doctor can lead to serious consequences - hypertension, heart attacks, strokes, stomach ulcers and other diseases. That is why a person experiencing chronic psycho-emotional stress should in no case ignore the appearance of unpleasant symptoms from the psyche, and in many cases it will be advisable to take drugs with a slight sedative (sedative) effect.

Of course, any drug must be prescribed by a doctor, especially when it comes to a potent substance in the composition of the drug, which can be sold in a pharmacy only by prescription. But there are sedative drugs that are completely harmless and available for sale in the pharmacy chain without a prescription. One of these drugs is valocordin.

Composition and mechanism of action of the drug

Valocordin is always available in the form of drops, the basis of which is water with 96% ethyl alcohol dissolved in it (411.97 mg and 469.75 mg, respectively). Phenobarbital and ethyl ester of bromisovaleric acid are dissolved in water, 18.4 mg of each substance. In addition, the composition of the drug includes peppermint oil (1.29 mg) and hop oil (0.18 mg).

The mechanism of action of valocordin, according to the instructions, is due to the properties of these substances that complement each other's effect.

So, phenobarbital has an anticonvulsant, sedative and mild hypnotic effect due to a slight inhibition of the transmission of impulses in the synapses of brain neurons.

Bromisovaleric acid ethyl ester similar in action to valerian rhizome, also having a hypnotic and sedative effect.

peppermint oil, the main active ingredient of which is menthol, promotes irritation of the receptors of the oral cavity and upper respiratory tract, which reflexively contributes to the expansion of the vessels of the heart, bronchi and brain. Thus, sedative and antispasmodic effects are also manifested.

Such effects are indispensable in the treatment of pathology of the nervous system, because this increases the blood supply to the brain, which reduces the risk of developing hypoxia - oxygen starvation. In addition, the processes of impulse conduction in the brain are inhibited in the patient, which is expressed in severe sedation within a few minutes after taking the drug.

Indications for taking valocordin

Usually, valocordin helps with functional disorders of the nervous system, while more serious diseases require the appointment of other drugs (antidepressants, tranquilizers, etc.). That is why it is better to consult a doctor before taking the drug. Nevertheless, any person can take valocordin situationally, for example, with strong psycho-emotional stress.

A course of valocordin is indicated for such disorders of the central nervous system as:

• Psycho-emotional lability, excessive and constant stress,
• Neurosis, in particular obsessive-compulsive disorder,
• Sleep disorders (, superficial short sleep, after which a person already wakes up tired and exhausted, nightmares, problems with falling asleep, etc.),
• Hypochondria, in which the patient looks for serious and dangerous illnesses, instead of recognizing the psycho-somatic factor.

In addition to functional disorders of the central nervous system, valocordin is indicated for vegetative-vascular dystonia, the manifestations of which are:

1. (pain in the region of the heart is not of an ischemic nature),
2. Headache, including migraine and/or tension headache,
3. The initial stages, especially in young patients due to constant stress, due to the relaxation of the smooth muscle of the vessels and a decrease in blood pressure,
4. - sweating, coldness of the skin of the extremities, chills and tremor of the extremities when exposed to a powerful stress factor, etc.),
5. Pain in the abdomen against the background of intense mental stress due to spasm of the smooth muscles of the intestine.

Quite often, valocordin is used to relieve an attack of angina, especially if the patient does not tolerate nitroglycerin. Some doctors are skeptical about taking valocordin in this case, because the “gold standard” for stopping an attack is precisely nitroglycerin. However, valocordin is really able to relieve an attack of pain in the heart for some time, as it has an effect that dilates the vessels of the heart, which ensures blood flow to the heart muscle. Of course Valocordin does not prevent the development of myocardial infarction, and sometimes even contributes to a serious outcome, because. the sedative effect often causes the patient to ignore the dangerous symptoms.

Contraindications

As a result of the fact that phenobarbital is metabolized in the liver cells, and the products of its metabolism (metabolites) are excreted from the body by the kidneys, the drug is contraindicated in severe stages of liver and kidney failure. In addition, phenobarbital affects the metabolism in the liver of other drugs, enhancing or weakening it. This can lead to the accumulation of metabolites of those drugs that the patient takes together with valocordin, and, as a result, to poisoning of the body.

In addition, pregnancy and lactation are an absolute contraindication for the use of valocordin, since not only ethyl alcohol, but also phenobarbital penetrates through the placenta and breast milk, which can have a negative effect on the developing brain of the fetus and newborn child. For pregnant and lactating women, it is only suitable to take valerian tablets (only as directed by a doctor!), But not valocordin.

Mode of application

The drug is used only inside, 15-30 drops three times a day before meals, after dissolving in a small amount of water, unless a different regimen is prescribed by the doctor. As a rule, the sedative effect occurs immediately, intensifying after a few days from the start of administration and reaching a maximum by the end of the first month of regular use. It is not recommended to take the drug for more than a month.

Are side effects possible?

Despite the fact that valocordin contains rather harmless substances, and phenobarbital is in low concentration, taking the drug can lead to undesirable consequences. So, the most common side effect is the occurrence of severe drowsiness and severe inhibition of psycho-motor reactions. Especially these phenomena often develop with an overdose.

When you first take the drug in extremely rare cases, allergic reactions may occur, from minor, like allergic dermatitis, to quite serious, like common urticaria and Quincke's edema. Of course, such reactions are very rare, but it is impossible to predict their occurrence due to the strictly individual reaction of each organism to a particular drug.

With prolonged use of the drug (more than a month), chronic bromine poisoning (in the composition of bromisovaleric acid) is possible, manifested by depression, apathy, chronic rhinitis and conjunctivitis).

Influence on the ability to drive transport

Due to the fact that valocordin should most often be taken by the patient more than once, but according to the course of treatment prescribed by the doctor, it is better for the patient to stop driving in the first days. If, after a few days, the patient is successfully adapted to increased inhibition in the cerebral cortex, and he does not have pronounced drowsiness and inhibition of the reaction, he can drive.

However, it should always be remembered that any reaction to the drug is strictly individual, and while some individuals retain the ability to have the normal reaction rate required when driving a car, then in another part of the patients, lethargy can be life-threatening and health as a result of insufficient concentration of attention behind the wheel.

Can I take the drug with alcohol?

Of course, in the life of every person, a situation may arise when he has the opportunity to drink alcohol - a birthday, a holiday with colleagues, etc. Phenobarbital, which is the main active ingredient, together with ethyl alcohol, which is in alcoholic beverages in an incomparably greater concentration, can give a rather unpredictable reaction. This is due to the fact that each person initially has a purely individual reaction to alcohol due to, again, the individual production of the alcohol dehydrogenase enzyme. If the work of this enzyme is insufficient, then the use of alcohol in combination with valocordin can lead to adverse consequences - severe intoxication, nausea, vomiting, up to alcohol poisoning. That is why the intake of alcoholic beverages during the course of treatment with valocordin is highly undesirable.

Drug analogues

Analogues of valocordin are drugs such as valoserdin and. The composition, mechanism of action and method of administration are identical, and the difference between them is only in the country of origin. So, valocordin is produced by European pharmaceutical factories, and these two analogues exist only in the Russian pharmaceutical market. The differences between these drugs are also in price - the cost of valocordin ranges from 150 rubles for 20 ml drops to 340 rubles for 50 ml drops. The cost of analogues is several times less - 16-20 rubles - the price of Corvalol and 50-70 rubles - the price of Valoserdin. In addition, the difference is a more convenient form of corvalol release in tablets, because it is not always possible to dissolve drops in water, and many people cannot tolerate the pungent smell of menthol in drops.

Thus, it should be noted that valocordin is a fairly effective drug that helps reduce psycho-emotional stress and manifestations of autonomic dysfunction. However, it should be understood that sedatives for the patient, like crutches for the lame, should only be used for the recovery period. That is, you can’t constantly take sedatives, and during their course you should make a lifestyle correction, rethink your attitude to constant nervous overload, learn how to rest and relax properly, in other words, develop a certain stress tolerance in yourself, because this is the key to a strong mind and healthy body.

Video: about valocordin in the program "Live healthy!"

Video: a report on the prospects of valocordin

For sleep disorders, insomnia, poor sleep, doctors recommend that patients take Valocordin. This complex acting drug has a relaxing effect on the central nervous system and helps to fall asleep faster, get rid of sleep problems. Familiarization with the instructions for use of the medication will allow you to use the product correctly.

What is Valocordin

According to the accepted medical classification, Valocordin drops are sedative (sedative) drugs. Additionally, it can be used as an antispasmodic, because it relaxes the smooth muscles of the internal organs. The drug has a complex composition - phenobarbital and ethyl bromisovalerianate are declared as active substances.

Composition and form of release

From the instructions for use attached to each bottle, you can find out the detailed composition of Valocordin in drops:

Valocordin action

In small doses, the active substances of the composition have a sedative and hypnotic effect, in high doses they have a narcotic effect. Phenobarbital is a derivative of barbituric acid, inhibits the inhibitory system of the reticular formation, is able to slightly lower blood pressure. The substance is absorbed in the stomach, 35% of the dose binds to plasma proteins, the rest is filtered in the kidneys.

Reabsorption of phenobarbital occurs at a low level of acidity, and reverse diffusion is impossible due to the alkalinity of urine. 30% of the substance is excreted in the urine, part is oxidized in the liver. Prolonged use of the drug leads to the accumulation of the substance in the plasma, liver enzymes are induced. This leads to an acceleration of the oxidation process of phenobarbital.

Ethyl bromisovalerianate has sedative and antispasmodic properties, acts like a phenobarbital synergist, that is, it provides a rapid onset of effectiveness. The substance releases boron in the body, which is slowly excreted from the body. Long-term use of the drug threatens with chronic boron intoxication. Peppermint and hop oils have reflex, vasodilating and antispasmodic effects.

Indications for use

The main purpose of using the medication is to eliminate the violation of falling asleep. In addition, indications for the use of the drug are:

• insomnia, cardiovascular cardialgia;
• sinus tachycardia, neurotic conditions;
• pain in the heart, ischemia of the heart muscle;
• vegetative lability, increased irritability;
• hypochondriacal syndrome;
• early stages of arterial hypertension;
• spasm of the muscles of the gastrointestinal tract (intestinal, biliary colic);
• anxiety caused by psychosomatic phenomena;
• brain disorders, neuroses, accompanied by a sense of fear.

How to take Valocordin

The drug is taken orally before meals, 15-30 drops. Previously, they are dissolved in 30-50 ml of water, repeated 2-3 times / day. With tachycardia, a single dose can increase to 40-50 drops. Children are shown 3-15 drops / day. The dosage for a child depends on the age and clinical picture of the disease. The course of taking the solution is determined by the doctor.

How long does Valocordin work?

Doctors note that the drug begins to act very quickly. This is due to the immediate absorption of active ingredients from the stomach. When taken on an empty stomach, the properties of Valocordin begin to unfold after a few minutes. Similarly, side reactions are quickly observed with individual intolerance, therefore, during treatment, it is worthwhile to carefully monitor the patient.

In the early stages of hypertension, Valocordin can be used to reduce pressure. It dilates blood vessels, relieves spasms, increases the clearance between the vascular walls. At low pressure, the medication should not be used, as it can aggravate the patient's condition and lead to critical symptoms if the recommended dosage is exceeded.

special instructions

When taking Valocordin, you need to pay attention to some indications of the instructions. Excerpts from the Special Instructions:

• the drug reduces the concentration of attention and the speed of psychomotor reactions, therefore, during the period of treatment, you should be careful when driving a car and operating mechanisms;
• if pain in the heart area does not go away after taking the medicine, consult a doctor to exclude the risk of acute coronary syndrome;
• the drug is used with caution in hyperkinesis, hyperthyroidism, adrenal hypofunction, heart failure, severe arterial hypotension, persistent pain, acute drug intoxication;
• long-term therapy with Valocordin is not recommended due to the risk of developing drug dependence, accumulation of bromine and the development of poisoning with this substance.

Valocordin during pregnancy

The drug is prescribed with caution by doctors during pregnancy and lactation, because phenobarbital and bromine can have a negative effect on the fetus and newborn. If the potential benefit to the mother outweighs the possible risk to the baby, the doctor will allow the use of the medication, but will carefully monitor all vital signs.

drug interaction

Some combinations of Valocordin drops with drugs are undesirable due to the risk of toxicity. Risky combinations:

• drugs that depress the central nervous system mutually reinforce the sedative-hypnotic effect of the drug, which threatens to stop breathing;
• phenobarbital accelerates the metabolism of coumarin derivatives, antibiotics, sulfonamides, enhances the action of analgesics, antipsychotics, anesthetics, tranquilizers, increases the toxicity of methotrexate;
• when used together, the effectiveness of Metronidazole, indirect anticoagulants, tricyclic antidepressants is weakened;
• monoamine oxidase inhibitors prolong the effect of phenobarbital, Rifampicin weakens its effect;
• non-steroidal anti-inflammatory drugs lead to stomach ulcers and bleeding;
• Combinations of Valocordin with thyroid hormones, Doxycycline, antifungal drugs from the azole group, Chloramphenicol, Griseofulvin, oral contraceptives, stimulants and glucocorticosteroids are undesirable due to the weakening of the action.

Alcohol compatibility

It is forbidden to combine Valocordin with alcohol, because they are both broken down in the liver. The composition of the drug also contains ethanol, so the liver has a double load. Ethyl alcohol increases the effect of phenobarbital and increases the toxicity of other components. Possible problems of the combination of the two components are painful colic, inhibition of the activity of the central nervous system, excitability or severe lethargy. The person suddenly falls asleep, there is a strong tremor of the limbs.

Side effects

The use of Valocordin entails the manifestation of side effects. Common are:

• drowsiness, dizziness, allergic reactions;
• decreased concentration, depression, apathy;
• rhinitis, conjunctivitis, hemorrhagic diathesis;
• chronic bromine poisoning, drug dependence, asthenia;
• weakness, impaired coordination of movements;
• nystagmus, ataxia, hallucinations;
• agitation, insomnia, fatigue, slow reactions;
• headaches, osteogenesis, rickets, osteopenia, osteoporosis;
• nausea, vomiting, constipation, heaviness in the epigastrium;
• agranulocytosis, anemia, thrombocytopenia, bradycardia;
• decrease in pressure, urticaria, angioedema;
• skin rashes, itching, acne, lacrimation, anxiety.

Overdose

Symptoms of an acute overdose of barbiturates are dizziness, fatigue, deep sleep (it is difficult to wake the patient), swelling of the face, rash, itching. Severe poisoning is manifested by tissue hypoxia, coma, palpitations, arrhythmia. Vascular collapse may occur, reflexes may be lost. Left untreated, pulmonary edema or respiratory paralysis develops, leading to death. Prolonged use of Valocordin leads to bromine poisoning, manifested by confusion, ataxia, apathy, depression, colds and acne.

Treatment of an overdose is to stabilize and normalize breathing, blood circulation in a hospital. The patient is given artificial respiration, the shock is eliminated by the introduction of plasma substitutes. For gastric lavage, activated charcoal and sodium sulfate are used. You can carry out forced diuresis, hemodialysis, hemoperfusion. Accelerates the excretion of bromine table salt solution with saluretic agents. In hypersensitivity reactions, antihistamines are indicated.

Contraindications

Valocordin is prescribed with caution during pregnancy, lactation. Contraindications for its reception are:

• hypersensitivity to components;
• severe liver or kidney failure;
• porphyria, diabetes mellitus;
• depression, myasthenia gravis;
• alcoholism, drug, drug addiction;
• respiratory diseases with shortness of breath, obstructive syndrome;
• severe arterial hypotension;
• acute myocardial infarction.

Terms of sale and storage

The drug is dispensed without a prescription, stored for five years at temperatures up to 25 degrees away from children.

Analogues

There are no complete analogues of Valocordin in composition, only approximate synonyms with the same active substances are distinguished. Substitutes include products with a similar effect. Drug analogues:

• Barboval - contains menthol in ether, is available in drops and capsules;
• Valecard - drops and tablets with a similar composition;
• Corvalcaps - capsules with a high percentage of active ingredients;
• Darvilol, Carditab, Corvalol, Corvaldin, Korvaltab, Morozov's drops are inexpensive analogues of the remedy.

Valocordin price

You can buy Valocordin in pharmacies and online stores. The cost of the drug depends on the volume and level of the trade margin. Approximate prices for a drug produced by the German company Crevel Meiselbach and its counterparts in Moscow will be.

Valocordin is a combination drug primarily used in cardiology. It is most often used to eliminate heart pain, tachycardia, nervousness or insomnia. At the same time, the medicine has a minimum of side effects, is relatively cheap, which contributed to its popularization. How to use Valocordin correctly? What dosage should be followed? Is it possible to overdose and what are its symptoms?

Valocardin is a solution based on the following components:

• ethyl ester of alpha-bromoisovaleric acid (2%);
• phenobarbital (2%);
• mint oil (0.15%);
• hop oil (0.01%).

As a medicinal base, ordinary ethyl alcohol is used in combination with distilled water. Alcohol also acts as a preservative that prevents the oxidation of the main components.

The ethyl ester of alpha-bromoisovaleric acid acts as a sedative, also gives a slight hypnotic effect, and at the same time is an antispasmodic.

Phenobarbital supplements the action of ether, and at the same time expands the lumen of blood vessels. Due to the latter, blood pressure is slightly reduced. This effect is complemented by mint oil, which also has a vasodilating effect on blood vessels and the cardiovascular system as a whole.

According to the instructions, indications for the use of Valocordin are:

• nervousness;
• high blood pressure (without severe hypertension in the chronic stage);
• tachycardia;
• spasms (narrowing) of the coronary vessels;
• insomnia;
• general irritability;
• sinus tachycardia.

Regarding hypertension, Valocordin can only be used in the initial stages of the disease. In an advanced case, the solution is not recommended for use, since the therapeutic effect will be insufficient.

Release form

At the moment, Valocordin is produced exclusively in the form of a ready-made solution for oral administration. Vials - 20 and 50 milliliters in a carton box with a special dispenser for easy counting of drops. Previously, Valocordin was also produced in the form of micro-vials for a single dose, but later manufacturers abandoned it (for financial reasons).

• 15-20 drops before the planned meal, washed down with a small amount of water, 2-3 times a day - with nervousness, high blood pressure;
• 30-40 drops before meals with water or unsweetened cool tea - with tachycardia, heart pain - up to 2 times a day;
• 3-10 drops 2 times a day - up to 18 years (the exact dosage should be checked with your doctor or pediatrician).

The course of treatment for each patient is compiled individually.

It should be borne in mind that with prolonged use of Valocordin, an addictive effect (slight dependence) occurs, and with a sharp cessation of administration, a “withdrawal” syndrome occurs. This is due to an increase in the concentration of bromine in the blood and subsequent "bromism" in the process of long-term therapy.

It is allowed to dissolve the drops before taking them in water or cooled unsweetened tea. The only caveat is no more than 30 milliliters of liquid per 10 drops. If there is more water, then the effectiveness of Valocordin will decrease due to the slow absorption of active ingredients into the blood.

Price

The average cost of Valocordin in pharmacies of the Russian Federation is 150 rubles. Different suppliers have slightly different prices (no more than 10 rubles).

Analogues

Analogues, completely identical in composition are the following drugs:

• Barboval. The composition is completely the same. Differences - only in the form of release. This medicine is available in 25 ml vials and oral capsules. The average price is 55-60 rubles (drops);
• Valecard. It also has an identical composition, but without mint oil and hop extract. Considered slightly less effective. The average price is 40-45 rubles (drops, 20 milliliters in a bottle);
• Corvalcaps. The same Valocordin, but in the form of capsules for oral administration. One pill corresponds to 15 drops. The average price is 100 rubles per package (10 tablets).

But analogues with a different composition, but with a similar effect, can be called the following drugs:

• Reladorm. It is mainly used to treat insomnia and nervousness. Available in tablets, the active substance is Diazepam and Calcium Cyclobarbital. Average price - 450 rubles (pack, 10 tablets);
• Somnol. The active substance is Zopiclone. It is mainly prescribed for sleep disorders, with emotional overstrain (single dose, without a course). Price - from 89 to 120 rubles.

If the doctor prescribed Valocordin, then you should not replace it with analogues at your discretion. In this regard, you should additionally consult with your doctor.

Contraindications

Contraindications, according to the official instructions, are:

• liver or kidney failure;
• hypersensitivity to active ingredients.

The drug is prescribed with caution during pregnancy and during lactation (lactation). Some active ingredients penetrate the bloodstream and from there are transported to the fetus or mother's milk.

A categorical contraindication is the simultaneous use of other sedative drugs. Their combination can adversely affect the functioning of the cardiovascular system, or even provoke a heart attack, severe hypotension.

With caution, Valocordin is also prescribed to people of retirement age (after 60-65 years) due to the possible negative impact on the cardiovascular system. For them, it is recommended to reduce the dosage to the lowest possible value (10 drops 2 times a day). In this regard, you need to consult with your cardiologist.

Possible side effects

Taking Valocordin may be accompanied by the following side effects:

• dizziness and headaches;
• drowsiness;
• slow reaction and decreased ability to concentrate;
• stomach upset;
• allergic reaction (hypersensitivity to the main components).

Long-term use of the drug may be accompanied by a slight dependence. To eliminate its symptoms, no manipulations should be taken. It is enough to refrain from taking Valocordin for 5-10 days.

Due to the fact that taking the drug is accompanied by a decrease in the speed of attention, it is worth taking it with extreme caution to people whose work directly depends on their reaction (drivers, conveyor line operators, and so on).

drug interaction

Taking Valocordin together with other sedatives leads to an increase in the effect of both drugs. The same applies to tranquilizers, antipsychotics, alcohol (and medicines based on it).

Joint reception with stimulants of the central nervous system reduces the effectiveness of the latter, and at the same time can contribute to a sharp increase in the frequency of contraction of the heart muscle.

Due to the fact that some components of Valocordin are absorbed in the liver (phenobarbital), it is not recommended to combine its administration with other drugs that also affect the functioning of the liver - this can provoke acute liver failure. And phenobarbital, as clinical trials show, inhibits the effect of oral contraceptives (non-hormonal type). Accordingly, it is temporarily worth refusing to take them, replacing them with condoms.

Overdose symptoms

The manufacturer of the drug does not report exact data on overdose. However, it is known that a single dose of more than 20 milliliters of Valocordin (corresponding to 1 bottle) can cause symptoms of combined intoxication. This is complemented by severe drowsiness, impaired coordination of movements. Visually, this is similar to the usual alcohol intoxication.

Excessive excess of the dose can provoke vascular collapse, as well as disruption of the central nervous system. The worst scenario is a violation of the respiratory function (from the side of the brain). If the victim is not provided timely assistance, then there is a high probability of death.

What to do with an overdose? First of all, rinse the stomach with plenty of water or potassium permanganate solution, and then symptomatic treatment is applied. Reception of sorbents will not give a positive effect. In critical cases, the patient is resuscitated (artificial respiration, chest compressions, forced ventilation).

Corvalol raises or lowers blood pressure. Composition of the drug, action and indications. Rules for taking Corvalol with high blood pressure.

Valocordin lowers blood pressure
How does corvalol affect blood pressure?
Corvalol is a well-known sedative that until recently was always in every home first aid kit. It is still used for various ailments associated with disruption of the cardiovascular system.

Corvalol dilates blood vessels, relieves tension, soothes. Its analogue is the equally well-known drug valocordin.
Corvalol contains the following substances:
ethyl ether;
phenobarbital;
alpha-bromoisovaleric acid;
mint oil.
relieves spasms;
significantly dilates blood vessels;
stabilizes the nervous system.
The main indications of Corvalol:
neuroses of any origin;
tachycardia;
insomnia;
vegetovascular dystonia with high blood pressure;
irritability, excitability, tearfulness.
Corvalol and pressure
Does corvalol increase or decrease blood pressure?

This question interests many who resort to his help for various reasons. This drug is a vasodilator, which means it lowers blood pressure. In this regard, the drug is often used by hypertensive patients to reduce blood pressure.
Corvalol is not recommended for people with low blood pressure, because it does not increase it, but lowers it.

Hypotensive patients can replace it with sedatives with a similar effect, but which do not affect blood pressure in any way. If a person with low blood pressure needs to drink Corvalol, you need to adhere to a certain dosage. Doctors in this case do not recommend taking more than 15 drops. Exceeding the dosage may result in fainting.
In what cases can Corvalol be taken as an antihypertensive agent?

It is allowed to take the drug to lower blood pressure in the following cases:
if high blood pressure is due to stress;
if high blood pressure is associated with vasospasm;
if the pressure has increased due to lack of sleep.
How to take Corvalol to lower blood pressure?
Drops drink from one to three times a day before meals. To do this, 30 drops are diluted in 50 ml of warm water and drunk in one gulp. After about half an hour, the pressure will decrease and improvement will come. If necessary, the dosage can be increased according to the doctor's prescription and be 40 drops.

If the drug is in tablets, you should drink one or two tablets twice a day.
Doctors categorically do not recommend drinking this remedy for hypertension for long courses. Its use is justified only if it is necessary to urgently reduce pressure, but there is no drug that a person usually takes with him.

If you still have to drink it, you need to take breaks or alternate with other drugs of the same effect. Doctors are categorically against the use of Corvalol as a means of preventing hypertension.
What is dangerous?
Nowadays, the attitude in the world to this drug is ambiguous. It is banned in some countries.

Corvalol is available in Russia, but doctors advise caution when using it. The fact is that taking it for a long time can lead to addiction. With regular use, a person may experience a bad reaction, dizziness, lethargy, constant drowsiness, nausea, short-term loss of consciousness. It contains phenobarbital, which has a hypnotic effect, so Corvalol should not be drunk by people whose activities are associated with increased concentration.
The benefits of Corvalol
Despite some negative effects, the drug also has useful qualities, including the following:

Corvalol relieves pain in the heart and promotes rapid falling asleep, deep and restful sleep.
It quickly eliminates emotional stress and panic, relieves irritability, palpitations, anxiety and excitement, and helps with stress.
Eliminates pain during intestinal spasms, relieves their manifestations.
It helps with headaches, so people suffering from this pathology take it in addition to the main pills.

Conclusion
Corvalol is a well-known, affordable and inexpensive drug. This makes it very popular for use in various situations associated with nervous tension and various experiences, with violations in the work of the cardiovascular system, including with an increase in pressure.

Despite the fact that the drug helps to reduce blood pressure, it is not recommended to abuse it. For the treatment of hypertension, there are many effective means, the choice of which is individual and is within the competence of a cardiologist.

It is very difficult for people who live in the modern world to avoid stressful situations. Many women and men experience irritability, suffer from neuroses. As a result, the general condition worsens, lethargy, insomnia, spasms, tachycardia appear, fatigue and blood pressure increase. It is important to monitor your health and use special sedatives in a timely manner. One of them is Valocordin - a sedative that is prescribed for disorders of the nervous system and the presence of cardiovascular diseases.

Composition of Valocordin

The drug is available in two dosage forms. Valocordin drops look like a clear liquid with a strong aromatic odor. They can be purchased in glass dropper bottles of 20 and 50 ml, packed in cardboard boxes. Another sedative is produced in the form of regular and soluble tablets (10 pieces per blister).

The composition of Valocordin is as follows:

Valocordin action

Drops and tablets are a combined medicine, the therapeutic effect of which is based on the pharmacological properties of the constituent elements. Valocordin contains ethyl bromisovalerianate (ethyl ester of α-bromisovaleric acid) and phenobarbital. These components have a hypnotic or sedative effect on the body, depending on the dosage. Phenobarbital refers to derivatives of barbituric acid, the substance inhibits the inhibitory system of the reticular formation. Sedative and antispasmodic effect gives ethyl bromisovalerianate.

Phenobarbital is absorbed very actively in the stomach. Further, 35% of the substance is bound by blood plasma proteins, and the rest is filtered in the kidneys. Reabsorption (reabsorption of fluid) occurs at a low pH level. Approximately 30% of phenobarbital is excreted unchanged from the body with urine, the rest of the substance is oxidized by the liver. If Valocordin is used for a long time, then the active component accumulates in the plasma, and the induction of liver enzymes also occurs. The procedure for the oxidation of phenobarbital is activated.

Indications for use

There are a number of conditions and diseases for which a sedative is prescribed. Instructions for the use of Valocordin include the following indications:

• insomnia, sleep disturbance;
• headache (migraine);
• flatulence (complex therapy);
• sudden attacks of angina pectoris (chest pain);
• neuroses;
• pain in the region of the heart (for example, cardialgia) caused by spasm of the coronary vessels;
• psycho-emotional overexcitation, which is provoked by a stressful situation;
• spasms of the gallbladder and intestines (if there is no obstruction of these organs);
• hypertension of the first stage (frequent and persistent increase in blood pressure).

How to take Valocordin

According to the instructions, drops or tablets are taken orally. The dosage and duration of the medication is prescribed by the doctor on an individual basis. Approximate average dosage of drops:

• high blood pressure, nervousness: 15-20 drops two to three times a day before meals with a small amount of water;
• tachycardia, pain in the heart area: twice a day, 30-40 drops, drink sweet tea or water;
• children from 14 to 18 years old 1-2 times a day, 3-8 drops.

Sometimes Valocordin is prescribed in tablets. The dosage of this dosage form is as follows:

• single dose: 15-25 mg per day;
• for the treatment of allergy symptoms: 25 mg every 4-6 hours (no more than 150 mg per day);
• children from 6 to 12 years: 6.25-12.5 mg every 6 hours.

special instructions

To avoid the manifestation of adverse reactions and not aggravate well-being, it is necessary to study the special instructions for the use of Valocordin. The main features that you should know when using the medication:

The drops contain 55% ethyl alcohol (ethanol).

When a person who has been taking phenobarbital for a long time abruptly stops the course of treatment, he may develop a withdrawal syndrome (accompanied by convulsions, delirium, a fatal outcome is likely).

The substance phenobarbital can be addictive. Physical and psychological dependence can manifest itself with prolonged use of drops or tablets in a large dosage. If the body quickly becomes addicted to the active ingredient, then the dose for effective therapy is increased.

Patients with acute or chronic pain should take phenobarbital with caution. This is due to an increased risk of paradoxical arousal and masking of serious clinical signs.

Chronic poisoning with a sedative drug can cause irritability, sleep disturbance, confusion, and somatic problems. Symptoms of an overdose are similar to those of a chronic form of alcoholism.

Valocordin during pregnancy

The drug should not be taken during pregnancy. Phenobarbital, which is contained in Valocordin, can cause a delay in fetal development, and ethanol can provoke the development of congenital malformations, anomalies, and even serious damage to the internal organs of the embryo. During lactation (breastfeeding), the use of a sedative medication is also contraindicated. Its active elements are able to penetrate into breast milk, and with it enter the body of a newborn. As a result, severe poisoning and depression of the central nervous system (CNS) develops.

drug interaction

The instructions for use describe the interaction of the drug with other drugs. During therapy, the following points should be considered:

1. If you use drops simultaneously with other sedative medications, antipsychotics and tranquilizers, then the effect of phenobarbital is greatly enhanced.
2. The active ingredient can reduce the effectiveness of oral contraceptives, griseofulvin and coumarin derivatives, and glucocorticosteroids.
3. If you use antipsychotics and tranquilizers with CNS stimulants, then the effect of phenobarbital is reduced.
4. Alcohol can enhance the medicinal effect of Valocordin by increasing the level of toxicity of the drops.
5. Doctors do not recommend drinking phenobarbital with drugs that are metabolized in the liver. Some of the components of the sedative may accelerate hepatic metabolism and increase the concentration of the constituent substances of Valocordin.

Side effects

In most cases, Valocordin is normally tolerated by the human body. If the dosage of the drug is not observed, personal intolerance to the drug and other reasons, side effects may occur:

1. Respiratory system: apnea (stopping respiratory movements), hypoventilation (lack of oxygen for tissues and organs).
2. Digestive system: attacks of nausea, vomiting, constipation.
3. Nervous system: mental disorders, agitation, anxiety, confusion, insomnia or drowsiness, ataxia (loss of coordination), hallucinations, nervousness, depression of the central nervous system.
4. Cardiovascular system: decreased blood pressure, bradycardia (slow heart rate), dizziness, fainting.
5. The development of anemia (decrease in hemoglobin concentration) with prolonged use of Valocordin. For the same reason, chronic bromine poisoning can occur with the following symptoms: apathy, hemorrhagic diathesis, impaired coordination of movements, rhinitis, depression, conjunctivitis.

Overdose

If you take Valocordin for a long period of time and do not follow the permitted dosage, then health problems may occur. The main symptoms of an overdose:

• weakness;
• bradycardia (sudden slowing of the heart rate);
• apathy;
• difficulty breathing, lack of oxygen;
• psychomotor disorders;
• intoxication of the body;
• dizziness, fainting;
• vascular collapse, impaired reflexes;
• a sharp drop in blood pressure.

Contraindications

In some cases, therapy with Valocordin is prohibited. Contraindications described in the instructions for the drug:

• age category up to 14 years;
• acute myocardial infarction;
• liver and kidney failure;
• brain diseases;
• traumatic brain injury;
• individual intolerance to the remedy;
• alcoholism;
• pregnancy, breastfeeding;
• cardiogenic shock.

Terms of sale and storage

You can buy a sedative at any pharmacy without a prescription. It is necessary to store drops or tablets out of the reach of children, at a temperature not exceeding 15º C. The shelf life of the sedative is 5 years.

Analogues

When a patient cannot be treated with Valocordin for a number of reasons, the doctor prescribes analog drugs. Often it is replaced by such drugs:

Valecard - drops with a sedative effect. They are prescribed for neurosis, functional lesions of the cardiovascular system, states of strong nervous excitement.

The drug Barboval, when used correctly, has an antispasmodic, sedative, hypotensive effect. The solution effectively relaxes the muscles and eliminates flatulence (bloating).

Another analogue of Valocordin is Corvalol tablets and drops. This drug gives a pronounced antispasmodic and sedative effect.

Corvaldin is a solution that restores normal sleep, calms the nervous system, relieves spasms.

Corvaltab tablets fight well with insomnia, help reduce the excitability of the central nervous system, and have a sedative effect.

Corvalcaps are capsules that are prescribed for tachycardia, minor spasms of the coronary vessels, neurosis with high irritability, vegetative dystonia, and insomnia.

Valocordin price

You can buy a drug in almost every pharmacy in Moscow and the region. It is also ordered in the online store at an affordable price (promotions, discounts apply). The approximate cost of funds is presented in the table.