Drops and eye ointment Maxitrol. Maxitrol eye drops Maxitrol eye drops instructions for use

Maxitrol is a combined topical ophthalmic preparation produced in Belgium. The tool can be used to treat infectious eye diseases, as well as to correct damage to the adnexa after medical procedures. If necessary, the use of Maxitrol is possible during pregnancy and lactation, but only if there are strong indications and under the supervision of a specialist. Information about the price of Maxitrol eye drops, as well as instructions for use, can be found on the Internet, but only the attending physician should diagnose and prescribe the dosage regimen.

Compound

Eye drops Maxitrol is a drug containing a combined formula of active ingredients, which is based on three components:

neomycin - an antibiotic produced in the form of sulfate and belonging to the group of aminoglycosides (3500 units in 1 ml);
dexamethasone - a glucocorticosteroid with anti-inflammatory and anti-allergic effects (1 mg in 1 ml);
polymyxin (in the form of polymyxin B sulfate) is an antibacterial component that reduces the permeability of the membrane membrane of bacterial cells.

The drug has a wide spectrum of antibacterial activity and is effective in infectious eye diseases caused by Haemophilus influenzae, aerobic bacteria, staphylococcus, Klebsiella and other types of gram-negative and gram-positive microorganisms.

The use of Maxitrol in diseases caused by streptococci is unjustified, since neomycin has a weak activity against these pathogens, and its use can provoke the development of superinfection against the background of secondary infection of the components of the eye.

The presence of dexamethasone in the composition allows the use of the drug in pathologies accompanied by inflammatory processes in the conjunctiva, cornea or retina. The agent has an anti-inflammatory effect, eliminates the manifestations of an allergic reaction, prevents the accumulation of exudate (fluid released from damaged blood vessels during inflammatory processes) in the eye cavity.

Dexamethasone promotes desensitization (desensitization) in older patients and reduces the risk of developing an infectious process.

Release form

Maxitrol (Latin name - Maxitrol) is available in two dosage forms:

solution for instillation into the conjunctival sac in the form of eye drops (in 5 ml vials with a dispenser nozzle);
eye ointment (in tubes of 3.5 g).

You can store the drug in the refrigerator (at a temperature not lower than + 8 °) or at room temperature (up to 30 °) for two years. Horizontal storage is not allowed. After opening the package, the medicine must be stored for four weeks. Shake the bottle before use.

Indications for use

Instructions for use of eye drops Maxitrol recommends using the remedy for infectious lesions of the components of the eye and its appendages.

The drug can be prescribed after surgery to prevent the inflammatory process and possible infection, which often occurs against the background of reduced local immunity. This is especially true for elderly patients, since the duration of the recovery period for them is almost 2 times longer than for patients of the middle age group.

Indications for the use of Maxitrol may be the following diseases:

chronic inflammation of the eyelids with the formation of purulent discharge (blepharitis);
infectious inflammation of the cornea, leading to clouding of the cornea, the occurrence of intense pain and the formation of ulcerative defects (keratitis);
bacterial infections of the mucous membrane (conjunctivitis);
inflammation of the choroid and iris (iridocyclitis).

Maxitrol is also effective in co-infections, such as keratoconjunctivitis, which often occur in immunocompromised patients over 50-55 years of age.

Side effects

Reviews of Maxitrol eye drops allow us to conclude that the drug is well tolerated, however, in some cases, side effects may occur. Negative reactions during treatment with the drug are most often caused by the content of dexamethasone. If Maxitrol is prescribed for more than 10 days, regular monitoring of intraocular pressure is required, since there is a high probability of damage to the optic nerve. Other side effects of topical glucocorticosteroids include:

visual field defects that occur against the background of a sharp increase in intraocular pressure (glaucoma);
clouding of the posterior wall of the lens of the subcapsular type (posterior cataract);
thinning of the cornea and ocular sclera with possible perforation (violation of integrity).

Maxitrol reduces the effectiveness of wound healing and regenerating drugs, so their simultaneous administration is not recommended.

Superinfection during treatment with Maxitrol

Superinfection is a rather rare complication of combination therapy, but the possibility of its occurrence cannot be completely excluded. The main factors contributing to secondary infection with bacteria or fungi are a steady decrease in the activity of immune cells and thinning of the cornea of the eye, which often occurs against the background of long-term (more than 10 days) treatment with topical steroid drugs.

The risk of developing superinfection is higher in patients older than 45-50 years, people with systemic chronic diseases, autoimmune disorders, as well as those living in unfavorable social and sanitary conditions. If signs of a secondary infection are found, treatment with Maxitrol should be stopped and another antibacterial drug should be selected, taking into account the identified pathogen and its resistance to antibiotics.

Contraindications

Maxitrol contains only antibacterial components, so the agent is ineffective in the treatment of viral and fungal infections of the eyes. Treatment with the drug for herpes zoster is contraindicated - a viral disease manifested by characteristic skin rashes and acute pain.

Eye infections caused by mycobacteria (for example, tuberculosis infection) require the use of other antibiotics, since neomycin does not have sufficient activity against this group of microorganisms.

It is forbidden to use Maxitrol with purulent ulceration of the cornea and after surgery to remove a foreign body.

Pregnancy and lactation are not a contraindication for the use of the drug, but treatment in this category of patients should be carried out according to strict indications. Teratogenic and embryotoxic effects on the fetus during the treatment of pregnant women have not been identified.

In pediatric practice, Maxitrol can be used without age restrictions after laboratory diagnosis of biological material (tear fluid).

Instructions for use

The standard dosage regimen for Maxitrol for mild to moderate infections is 1-2 drops every 4-6 hours. Instillations should be carried out on both eyes to prevent infection of healthy tissues. The agent should be instilled into the conjunctival sac, tilting the head back and gently pushing the edge of the lower eyelid down.

In severe bacterial lesions of the eyes, the procedure must be repeated every hour. After reducing the main symptoms and improving the patient's condition, you should switch to the standard treatment regimen. The duration of therapy should not exceed 10 days.

Price

The price of Maxitrol eye drops depends on the region and method of sale (in online pharmacies, the cost is usually 3-10% lower compared to network pharmacies). The average cost of one bottle is:

in Moscow - 490 rubles;
in St. Petersburg - 472 rubles;
in Yekaterinburg - 513 rubles.

The minimum cost in online pharmacies is 414 rubles per bottle. On the territory of Ukraine, the drug can be bought for 120 hryvnia.

Analogues

Analogues of Maxitrol eye drops may be required if the drug is poorly tolerated, symptoms of an allergy to the components of the drug are detected, or treatment is ineffective. Listed below are medicines with a similar composition or similar medicinal properties.

Maxitrol (eye ointment). Ointment Maxitrol is an absolute analogue of eye drops with an identical composition. In some regions, the drug has been withdrawn from sale, so you can only buy it on order.
Dex-Gentamicin. Combination preparation containing dexamethasone and gentamicin sulfate (antibiotic). Contraindicated in the first trimester of pregnancy and childhood (up to 18 years). Available in the form of drops and ointments. The average cost is 126 rubles.
Tobradex. Tobradex eye drops contain dexamethasone and tobramycin (an antibiotic from the aminoglycoside group). Unlike Maxitrol, it has a high activity against streptococci. The cost of the medicine starts from 350 rubles.

Changing the drug without consulting a doctor is not allowed.

Redness of the eyes is not always caused by banal overwork. Sometimes the cause of a change in the color of the mucous membrane becomes one or another disease. The most common is conjunctivitis, an unpleasant ophthalmic ailment that anyone can experience, regardless of age and gender.

The disease can be both allergic and infectious. Moreover, the latter variety is easily transmitted by contact. Therefore, if you often visit crowded places, forget to wash your hands when you come from the street, then the likelihood of getting such inflammation of the eyes increases many times over.

Also at risk are people who, on duty, are forced to inhale the fumes of varnishes and chemical reagents. They also cause conjunctivitis.

Even ordinary shampoos and cleansers, as well as low-quality cosmetics, can cause inflammation of the eyes.

Therefore, it is important to know which drug will help you and your loved ones cope with this disease, which forms not only physical, but also aesthetic discomfort.

Note that Maxitrol eye drops not only relieve unpleasant symptoms - itching, redness, lacrimation, and others. They defeat inflammation and effectively fight infection.

This unique medical product has both anti-inflammatory and bactericidal effects, has virtually no side effects and has proven itself in the treatment of many ophthalmic problems.

Note! Eye drops "Maxitrol" are released exclusively by prescription.

Compound

This drug contains antibiotics and dexamethasone. This combination avoids further infectious development.

Note that Maxitrol is one of the drugs with proven effectiveness.

Components in the composition:

Neomycin. Antibiotic complex. It has antibacterial and bactericidal action.
Polymyxin B. Antibacterial, bactericidal substance. Active against microorganisms such as Salmonella, Bordetella pertussis, Enterobacter and others.
Dexamethasone. Belongs to the number of glucocorticosteroids (substances similar to natural steroid hormones). Helps relieve inflammation and swelling, as well as relieve allergic symptoms.

Additional components: water, sodium chloride, sodium hydroxide, benzalkonium chloride, hypromellose.

When to Use

Maxitrol eye drops are broad-spectrum drugs and are effective in the treatment of various diseases.

Problem	Description	Main symptoms
Conjunctivitis	A disease characterized by inflammation of the mucous membrane of the eye, allergic or infectious etymology	Eye redness, photophobia, eyelid swelling
Blepharitis	Chronic disease of the eyelids, characterized by their inflammation; it can be purulent, ulcerative, scaly, seborrheic, etc.	Swelling of the eyelids, itching, redness, loss of eyelashes
Keratitis	Inflammatory disease of the cornea	Tearing, decreased visual acuity, pain
Blepharoconjunctivitis	Inflammatory disease of the mucous membranes of the eyes and eyelids	Swelling and redness of the mucous membrane of the eye and eyelids, photophobia, itching
Keratoconjunctivitis	Inflammatory disease of the mucous membrane and cornea of the eye	Pain in the eye, redness, itching, lacrimation

If you notice one or several of these symptoms at once, Maxitrol eye drops can help you, including in complex therapy in combination with other ophthalmic drugs. But, of course, you will first need to consult with an ophthalmologist. The effectiveness of the treatment of inflammatory eye diseases directly depends on the correctness and timeliness of the diagnosis.

This is interesting! Drops "Maxitrol" are also used in otolaryngology. The drug is effective in the treatment of profuse rhinitis and otitis media. ATTENTION! If you are using this remedy for conjunctivitis and otitis at the same time, it is recommended to use different bottles for the eyes and ears. Otherwise, the risk of spreading the infection is increased.

Where to buy and who makes

Maxitrol eye drops are sold exclusively in pharmacies. Do not buy the drug from the hands! Indeed, in this case it is easy to stumble upon a fake, an expired medicine or a medicine that has become useless or even dangerous due to violation of storage conditions.

"Maxitrol" should be stored at a temperature not higher than 30 degrees and not lower than 8, in a dry place, away from sunlight.

The manufacturer of Maxitrol is the American company Alcon, a recognized leader in the ophthalmological market.

Maxitrol eye drops are medicines of the middle price range, available to a wide range of consumers.

Methods of application and dosage

The drug should be used in strict accordance with the instructions and recommendations of the attending physician.

In the first few days of use, the drug should be instilled, including at night with an interval of about 2 hours.

Dosage: 1-2 drops in each eye.

As treatment progresses, the number of instillations decreases to 5-6.

The course is from 5 to 7 days. However, in some cases, the doctor decides to increase the duration of the course.

Attention! If you wear contact lenses, then before using the drug, you must remove them. Re-installation is possible 20 minutes after using Maxitrol.

Video - How to drip drops into the conjunctival sac of the eye

Contraindications

Before using these eye drops, you should make sure that they are not contraindicated for you.

You can not use "Maxitrol" when:

chickenpox;
tuberculosis;
cataract (with caution);
glaucoma (with caution);
fungal eye infections;
hypersensitivity to the components of the drug;
purulent mucosal infection.

Note: cases of drug overdose have not been identified.

Things to Remember

If the doctor prescribed the ophthalmic drug "Maxitrol" for treatment, it should be borne in mind that:

after opening the package, these eye drops can be stored for no more than four weeks;
you can not use the drug simultaneously with other drugs, you should pause at least 10 minutes between instillations;
"Maxitrol" - eye drops for adults, in pediatrics, the appropriateness and effectiveness of the use of this drug have not been established;
drops are not recommended for use during lactation;
treatment of pregnant women - with caution, as directed by a doctor.

In addition, when using Maxitrol eye drops, side effects of a predominantly local nature may develop. So, the drug can cause an allergy, expressed in itching, swelling and redness. If such symptoms are noted, it is necessary to stop using the drops and consult with your doctor.

Should know! When using the drug for a long time - more than 10 days - you should be examined for an increase in intraocular pressure.

Maxitrol is designed to relieve inflammation from the eyes, it is a combination drug that is applied topically.

Indications for use

As mentioned above, Maxitrol is used to relieve eye inflammation. Shown in the following cases:

Bacterial inflammation of the eyelids (blepharitis)
Eye infection (conjunctivitis)
Keratitis
Iridocyclitis
Chemical contact with the mucous membrane of the eye, burns or mechanical damage
Preventive measures after surgery to prevent possible complications

Compound

The drug contains active ingredients: 1.0 milligrams of dexamethasone, 6000 IU of polymyxin B and 3500 IU of neomycin.

Additional substances: sodium hydroxide, polysorbate 20, sodium chloride, benzalkonium chloride, hypromellosum, distilled water.

Medicinal properties

The effective drug Maxitrol (ointment, drops) relieves inflammation and kills bacteria. The most active ingredient in the composition of the drug is dexamethasone (a corticosteroid). In combination with antimicrobial agents, it stops inflammatory processes. The bactericidal action is provided by the antibacterial auxiliary component of neomycin sulfate. Selective action (selective), which is directed to gram-negative bacteria, has polymyxin B sulfate.

Additional components of the drug Maxitrol are easily absorbed when the tissues of the eye are injured after external use. The corticosteroids present in the preparation are absorbed into the cornea, iris, retina and ciliary body.

Drops "Maxitrol"

Average price: 450 rubles

Maxitrol eye drops are a white or yellowish opaque suspension in a 5 ml bottle with a dropper cap.

Dosage and administration

Shake the bottle before using Maxitrol eye drops. In mild forms of the disease, it is recommended to instill 1-2 drops of the drug into the conjunctival sac 4 to 6 times a day. With the course of the infectious process in a severe form, the drug can be dripped in an hour and a half. To avoid infection in the eyes, do not touch the vial dispenser. After instillation, the cork must be tightly closed.

To properly drip Maxitrol eye drops, it is recommended to do the following:

Wash the hands
Tilt your head back
Pull the lower eyelid down slightly, look up
Make an instillation between the eyelid and the eye
Close your eyes and press the corners (internal) 1-2 minutes.

Ointment "Maxitrol"

Average price: 400 rubles

Eye ointment is opaque, white to light yellow in color, the tube contains 3.5 g of the product.

Packaging - 1 tube in a cardboard box, plus instructions for use.

Dosage and administration

Ointment, lay behind the eyelid three times a day with a column thickness of 1-1.5 centimeters. Additionally, you can apply the ointment before bedtime. When using the ointment, in no case should you touch the tip of the tube.

Contraindications

Do not prescribe Maxitrol (drops, ointment) to patients who are intolerant to the components of the drug, with eye diseases caused by a viral infection, with lichen or fungus in the eye area, with infectious diseases with pus.

Particular attention is required to prescribe a remedy for cataracts or glaucoma.

When using the drug, precautions should be taken. Do not use in hypersensitive skin. Do not wear contact lenses during treatment.

Pregnancy and lactation period

Volumetric reliable data on the use of Maxitrol during lactation and pregnancy are not available. It can be used by a pregnant woman, but only the doctor in whom she is observed can make an appointment. For the period of breastfeeding, the use of the product is prohibited.

drug interaction

Studies show that no interactions of Maxitrol with other drugs have been identified when used in ophthalmology. With the simultaneous use of the drug with ophthalmic drops or ointments, it should be instilled with a break of 10-15 minutes.

Side effects

Sometimes the use of the drug may be accompanied by concomitant phenomena:

Increased intraocular pressure
Allergy
Corneal perforation

Overdose

Long-term use of Maxitrol in large quantities can cause a number of side effects. Maintenance therapy is required in case of overdose.

If during the application more drops got into the eyes than provided for by the instructions, the mucous membrane must be rinsed with warm water.

Terms and conditions of storage

Store the vial or tube at a temperature of 10–30 °C. Preferably away from the sun. Exclude the possibility of access to children.

The validity period is 24 months. After opening - 1 month.

Analogues

Synonyms for Maxitrol are:

Manufacturer - E.I.P.I. Co., Egypt.
Price- 400-500 rubles.

The preparation of the three components of neladex (polymyxin B, glucocorticosteroid and neomycin). Unflavored whitish suspension. It has an antibacterial effect and relieves inflammation.

Pros:

Rapidly absorbed
Has a systemic effect.

Minuses:

Not recommended for use during pregnancy
When applied, a secondary infection may develop.

You came to us, dear user, and you can be sure that you will not regret it. And do you know why? Because our site first of all thinks about you! We specifically try to present all the information, even the most complex, in such a way that it is as clear as possible to you.

The questions we are considering here are very different and we do not want to lose those who regularly use our articles. Therefore, we speak simply and accessible even about diseases and medicines. For example, now we will talk about what maxitrol is, the instructions for use of which can help you decide whether it will cure your particular problem?

What is the drug?

Let's start with you, to begin with, we will understand the composition and pharmacological properties of this eye, combined remedy. Let's start with the fact that this drug is widely used in ophthalmology. To be a little more specific, he fights against inflammatory and infectious processes that occur in the eyes.

Dexamethasone (1mg) - acts against allergies, inflammation and excessive vascular permeability.
Polymyxin B - effectively blocks the excessive permeability of the membrane (cytoplasmic).
Neomycin sulfate - having a bactericidal effect, it prevents protein synthesis in a foreign, microbial cell.

The main component that has an effect on the diseased organ is precisely dexamethasone. Maxitrol is used exclusively locally (installations). And if antibiotics are used along with it, the risk of infection is significantly reduced.

Application of the drug

Of course, we have already informed you that Maxitrol is released as a remedy for treating eye diseases. But let's take a closer look at exactly which of them are in his "paraphia":

keratitis,
conjunctivitis (-kerato-, -blepharo-),
chronic and bacterial blepharitis,
uvitis (iridocyclitis, cyclitis, iritis),
damaged cornea (trauma, radiation, chemicals, foreign bodies, thermal burns).

Can be used in conjunction with antimicrobials if microorganisms in the eye are too high or there is a high chance of infection. It is also practiced for preventive purposes, in the postoperative period, in the fight against infectious complications.

It is acceptable to treat cataracts and glaucoma, but it is important to be careful when taking and using caution. Before you start taking the medicine, be sure to consult with your doctor.

How to use Maxitrol

But how is the instillation procedure performed, and in what doses should it be done? It is best to perform all actions strictly according to the instructions and under the supervision of an experienced ophthalmologist. After all, treatment and doses directly depend on how long the disease has dragged on and to what “stage” it has reached. It makes the following recommendations:

mild form of the disease. 1 or 2 drops of liquid should be instilled directly into the conjunctival sac. Depending on the course of the disease, do this about 4-6 times a day.
Severe form of the disease. In this case, the procedure should be carried out, almost every hour, all also 1-2 drops.

All treatment should last about 6, and a maximum of 10 days. When instilling, try not to touch the tip of the bottle not only to the eye, but also to any objects around you.

To facilitate this process, try to pull the lower eyelid and look up, and then close and press the inner corner of the eye with a cotton swab. This will increase the effect of the drug and reduce some unpleasant side effects.

Side effects

As with any drug, Maxitrol also has consequences that may manifest itself in those who have a special sensitivity or disease that reacts negatively to the drug. Let's pay attention to them to be extremely careful:

dry eyes,
burning,
redness,
pain sensations,
feeling of the presence of a foreign body,
decreased vision,
blurred eyes,
high pressure (intraocular),
nerve damage (ocular)
long wound healing
tearing,
allergic reaction (irritation, redness, itching, rash),
angioedema,
anaphylactic shock.

These side effects are due to the action of the steroid. As a result of their long-term use, a fungal infection may even develop.

Contraindications

As for pregnant women, they are not included in the risk zone. The exception is mothers who are breastfeeding their babies. But those who have the eye diseases described below should seriously think before proceeding with treatment:

fungal diseases;
personal intolerance to the components;
eye tuberculosis;
after removal of a foreign body;
purulent infection of the mucosa;
corneal ulcer;
lichen (shingles);
special sensitivity to antibiotics.

About whether it is permissible to use this remedy for the treatment of children, nothing is said in the instructions. If you use Maxitrol in parallel with other similar drugs, then keep an interval of approximately 10-15 minutes.

Some Directions

The shelf life of this tool is 2 years, but this is provided that you did not open it and it was in a dry, cool and dark place. If you have already opened it, then the period is reduced to one month.

And one more reminder: before opening, the bottle must be shaken well, and after use, be sure to close it. It must be in a vertical position.

On this, I would like to end our excursion into the world of the drug "Maxitrol". We really hope that you are satisfied, our dear user. In any case, please know that we have tried very hard to make you feel comfortable with us.

One milliliter of eye drops contains 3500 units. neomycin sulfate and 6000 units. polymyxin (B) sulfate, as well as 1 mg dexamethasone and excipients: neutral additives, polysorbate 20, hydroxypropyl methylcellulose (0.5%), distilled water. 0.004% benzalkonium chloride was used as a preservative.

Eye drops are available in 5 ml bottles with Drop-Taner drip. Each bottle is sealed in a cardboard box.

It has a local antibacterial and anti-inflammatory effect.

Maxitrol eye drops is a combination drug that is used in ophthalmology. Neomycin able to disrupt protein synthesis (bactericidal action, development of resistance is slow and to a small extent) in bacteria such as:

Staphylococcus aureus(Staphylococcus aureus);
bacteria-diphtheria pathogens(Corynebacterium diphtheriae);
low pathogenic streptococcal bacteria (Streptococcus viridans);
coli(Escherichia coli);
Friedlander's stick (Klersiella pneumoniae);
common proteus (Proteus vulgaris);
gram-negative rod-shaped bacterium (Aerobacter aerogenes);
hemophilic bacillus (Haemophilus influenzae).

Wherein neomycin not active against pathogenic fungi, viruses and anaerobic flora.

The active substance of this drug is Polymyxin B sulfate acts by blocking the permeability of the cytoplasmic membrane of cells of a number of bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, coli And Friedlander sticks, and bacilli Koch-Weeks, causing conjunctivitis.

Dexamethasone is glucocorticosteroid, which has an anti-inflammatory, anti-allergic, anti-exudative and desensitizing effect. In combination with antibiotics significantly reduces the risk of infection.

Pharmacokinetics

Topical application is characterized by a low level of systemic absorption.

Maxitrol eye drops are usually used for various infections of the eyes and appendages:

at blepharitis;
conjunctivitis;
keratoconjunctivitis;
keratitis;
iridocyclitis;
as well as prevention V postoperative period at inflammation front eyes.

The drug should be used with caution when glaucoma And cataract.

Local side effects usually manifest as allergic reactions accompanied by itching, swelling of the eyelids And reddening of the conjunctiva.

The steroid component causes increased intraocular pressure with subsequent development glaucoma, damage to the optic nerve and visual fields, posterior cataract of the subcapsular type, delayed wound healing.

In addition, the course of treatment - more than 10 days requires monitoring of intraocular pressure;

In addition, there may be:

secondary infection with glucocorticosteroids And antibiotics;
fungal infection cornea with long-term use steroids up to education non-healing ulcers testifying to fungal invasion.

Method of application: topically, in the conjunctival sac. Before use, shake the bottle with drops, after - be sure to close.

The instruction for Maxitrol eye drops differs from the severity of the infectious process:

mild form - 1-2 cap. must be instilled every 4-6 hours;
severe infectious process - 1-2 drops. should be instilled every hour, as the inflammation decreases, the frequency of instillations of the drug can be reduced.

At the moment, there are no cases of overdose with topical application.

If it is necessary to use other local ophthalmic agents, the interval before using the next drug should be at least 10 minutes.

The drug is dispensed in pharmacies only by prescription.

In a place inaccessible to children. Keep the temperature between 8-30° Celsius and keep the vial in an upright position.

Two years. After opening the vial - up to 4 weeks.

Analogues of eye drops that can reduce the risk of developing inflammatory processes:

Dex-Gentamicin
Dex-Tobrin
Medetrom
Polydex
Polydex with Felinefrin

Reviews of eye drops are few, since the drug is dispensed in pharmacies only by prescription, but those who used Maxitrol note that it helps, does not burn the eyes and does not cause other adverse and allergic reactions.

The price of eye drops in a 5 ml bottle is 350-440 rubles.

Maxitrol 0.1% eye drops 5ml dropper bottleAlcon-Couvreur N.V.S.A.

MaxitrolAlcon-Couvreur, Belgium

MaksitrolAlcon-Couvreur (Belgium)

Maxitrol eye drops 5 ml

Maxitrol 3.5 g eye ointment

Clinical and pharmacological group

Drug with antibacterial and anti-inflammatory action for local use in ophthalmology

5 ml - polyethylene bottles with a dropper Drop-Teiner (1) - packs of cardboard.

pharmachologic effect

Neomycin has a bactericidal effect, disrupting the bacterial cell protein synthesis. Active towards Staphylococcus aureus, Corynebacterium diphteriae, Streptococcus viridans, Escherichia coli, Klepsiella pneumoniae, Proteus vulgaris, Aerobacter aerogenes, Haemophillus influenzae.

The mechanism of action of polymyxin B is mainly due to the blockade of the permeability of the cytoplasmic membrane of bacterial cells. Active towards Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Klersiella pneumoniae, Koch-Weeks bacillus.

Dexamethasone

GKS. It has anti-inflammatory, anti-allergic and desensitizing effect. Has an anti-exudative effect. Dexamethasone effectively suppresses inflammatory processes.
The combination of corticosteroids with antibiotics can reduce the risk of developing an infectious process.

Pharmacokinetics

Infections of the eye and its appendages:

Blepharitis;

Conjunctivitis;

Keratoconjunctivitis;

Keratitis;

Iridocyclitis.

Contraindications

Individual hypersensitivity to the components of the drug;

Viral eye diseases (including keratitis caused by Herpes simplex, chickenpox);

mycobacterial eye infection;

Tuberculous diseases of the eyes;

Acute herpes zoster;

Fungal diseases of the eyes;

Condition after removal of a foreign body of the cornea;

Purulent infection of the mucous membrane of the eye and eyelids, caused by neomycin-resistant microorganisms, purulent corneal ulcer.

Carefully prescribed for glaucoma, cataracts.

Dosage

locally. At mild infectious process 1-2 drops in the conjunctival sac 4-6 times / day.

At acute severe infectious process 1-2 drops in the conjunctival sac every 60 minutes with a decrease in the frequency of drug instillations as inflammation decreases.

Side effects

Local. An allergic reaction, accompanied by itching and swelling of the eyelids, conjunctival hyperemia. Side effects caused by the steroid component: increased intraocular pressure with possible subsequent development of glaucoma, damage to the optic nerve and visual fields (when using the drug for more than 10 days, monitoring of intraocular pressure is necessary); posterior subcapsular cataract, slowing down the wound healing process. Topical application of steroids for diseases that cause thinning of the cornea or sclera can lead to their perforation.

secondary infection. The development of a secondary infection is observed after the use of combined preparations containing corticosteroids in combination with antibiotics. With prolonged use of steroids, the development of fungal infections of the cornea is possible. The appearance of non-healing ulcers on the cornea after prolonged treatment with steroid drugs may indicate the development of a fungal invasion. Secondary bacterial infection may occur as a result of suppression of the patient's protective reaction.

drug interaction

Interaction with other drugs is currently not known.
In the case of use with other local ophthalmic preparations, the interval between their use should be at least 10 minutes.

The safety and efficacy of the drug in children have not been established.

The drug is dispensed by prescription.

Tradename: Maxitrol

International Nonproprietary Name/Group Name:
Dexamethasone + Neomycin + Polymyxin B

Chemical Name:
Dexamethasone: 9-fluoro-11β, 17, 21-trihydroxy-16α-methylpregna- 1,4-diene-3,20-dione
Neomycin sulfate: 2-deoxy 4-0-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-0-D-streptamine (neomycin B) sulfate
Polymyxin B sulfate: a mixture of polypeptide sulfates

Composition of 1 ml of the preparation
Active substances: dexamethasone 1.0 mg;
neomycin sulfate 3500 ME;
polymyxin B sulfate 6000 ME.

Excipients: benzalkonium chloride solution, equivalent to benzalkonium chloride; sodium chloride, polysorbate 20, hypromellose* (4000 mPa.s), concentrated hydrochloric acid and/or sodium hydroxide to adjust the pH, purified water.
* Synonym: Hydroxypropyl methylcellulose

Description: opaque suspension from white to light yellow

Pharmacotherapeutic group
Glucocorticosteroid + antibiotics (aminoglycoside and cyclic polypeptide).

ATX code: S0lCA0l

pharmachologic effect

Pharmacodynamics
Combined preparation for topical use in ophthalmology.

Neomycin has a bactericidal effect, disrupting the bacterial cell protein synthesis. Active against Staphylococcus aureus, Corynebacterium diphteriae, Streptococcus viridans, Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Aerobacter aerogenes and Haemophilus influenzae.

The mechanism of action of polymyxin B is mainly due to the blockade of the permeability of the cytoplasmic membrane of bacterial cells. Active against Pseudomonas Aeruginosa, Aerobacter aerogenes, Escherichia coli, Klebsiella pneumoniae and Koch-Weeks bacillus.

Dexamethasone is a glucocorticosteroid. It has anti-inflammatory, anti-allergic and desensitizing effect. Has an anti-exudative effect. Dexamethasone effectively suppresses inflammatory processes. The combination of a glucocorticosteroid with antibiotics can reduce the risk of an infectious process.

Pharmacokinetics
When applied topically, systemic absorption is low.

Indications for use
Infections of the eye and its appendages:

blepharitis;
conjunctivitis;
keratoconjunctivitis;
blepharoconjunctivitis;
keratitis;
iridocyclitis;

Prevention of postoperative infectious complications.

Contraindications

individual hypersensitivity to the components of the drug;
viral eye diseases (including keratitis caused by Herpes simplex, chickenpox);
mycobacterial eye infection;
tuberculosis diseases of the eyes; acute herpes zoster; fungal diseases of the eyes;
condition after removal of a foreign body of the cornea;
purulent infection of the mucous membrane of the eye and eyelids caused by neomycin-resistant microorganisms, purulent corneal ulcer

Carefully
Be wary appoint glaucoma, cataracts.

Use during pregnancy and lactation
Sufficient experience in the use of the drug during pregnancy and lactation is not. It is possible to use for the treatment of pregnant women as prescribed by the attending physician, if the expected therapeutic effect outweighs the risk of possible side effects. It is necessary to interrupt the use of the drug for the period of breastfeeding.

Application in pediatrics
The safety and efficacy of the drug in children have not been established.

Dosage and administration
locally. With a mild infectious process, 1-2 drops in the conjunctival sac 4-6 times a day.

In acute severe infectious process, 1-2 drops into the conjunctival sac every 60 minutes, with a decrease in the frequency of drug instillations as inflammation decreases.

Side effects

Local. An allergic reaction, accompanied by itching and swelling of the eyelids, conjunctival hyperemia.

Side effects caused by the steroid component: increased intraocular pressure with possible subsequent development of glaucoma, damage to the optic nerve and visual fields (when using the drug for more than 10 days, monitoring of intraocular pressure is necessary); posterior subcapsular cataract, slowing down the wound healing process. Topical application of steroids for diseases that cause thinning of the cornea or sclera can lead to their perforation.

secondary infection. The development of a secondary infection is observed after the use of combined preparations containing glucocorticosteroids in combination with antibiotics. With prolonged use of steroids, the development of fungal infections of the cornea is possible. The appearance of non-healing ulcers on the cornea after prolonged treatment with steroid drugs may indicate the development of a fungal invasion. Secondary bacterial infection may occur as a result of suppression of the patient's protective reaction.

Interaction with other drugs
Interaction with other drugs is currently not known. In the case of use with other local ophthalmic preparations, the interval between their use should be at least 10 minutes.

special instructions
The bottle must be closed after each use. Shake the bottle before use.

Release form
Eye drops. 5 ml in a Droptainer™ dropper bottle made of low density polyethylene. 1 bottle with instructions for use in a cardboard box.

Storage conditions
List B. Store at a temperature of 8 to 30°C. Keep out of the reach of children.

Best before date
2 years. Use within 4 weeks after opening the vial.
Do not use after the expiry date stated on the package!

Holiday conditions
By prescription.

When it comes to antibiotics in the field of ophthalmology, first of all, Maxitrol drops should be mentioned. Thanks to their action, an important process of suppressing infection begins to occur in the body, which leads to recovery. This drug is combined, and is used not only in the treatment of diseases of a bacterial nature. It is also effective in the treatment of inflammatory processes caused by a virus and allergies.

Like all such drugs, Maskitrol is available in special small bottles, only 5 ml in volume. For convenience, the bottle is made in such a way that it is convenient to use it at any time and in any place, that is, together with a dropper. It is a suspension, the color of which can vary from white to yellowish.

These drops are designed to have an antibacterial effect, and serve as an anti-inflammatory agent. The main tasks are performed due to active substances:

Neomycin.
Dexamethasone.
Polymyxin B sulfate.

Thanks to the latter substance, the body blocks the penetration of a number of bacterial pathogens, such as Pseudomonas aeruginosa and E. coli, Friedlander's bacillus, and bacilli that can provoke some diseases.

Auxiliary components include:

non-alkonium chlorite preservative,
sodium chloride,
polysorbate 20,
hypromellose,
distilled water.

First of all, the medicine is produced to get rid of infections of the eye organs and their appendages, such as:

bacterial keratitis.
Conjunctivitis of an allergic and non-purulent form.
Keratoconjunctivitis.
Iridocyclitis.
For burns, barley.
As a preventive measure after surgery.

The drug has a lot of contraindications, so you should study the instructions before you start using this remedy. It is completely forbidden to use the drug with diseases such as:

Tuberculosis of the organs of vision.
Fungal and viral infections.
With purulent forms of infections, including suppuration on the cornea.
Glaucoma and cataract.
If a foreign body is removed.
In cases of infectious damage to the eardrums.
If a person has chickenpox.

There are no special instructions regarding pregnant women, so the decision to use Maxitrol remains with the doctor. If the need to take the medicine outweighs the possible risks, during pregnancy and lactation, the patient is used, but with extreme caution.

For children, there are also no contraindications, nor any special effective or safe effects of the drug, therefore, if it is possible to replace it with another remedy, this should be done.

Try to keep the medicine in a place where children do not have access. And another important point that should be considered before the instillation procedure is shaking the vial.

In cases where an overdose is observed, or the solution accidentally got inside the body, gastric lavage should be done and the doctor should be notified.

Local side effects may occur, such as an allergic reaction in the form of itching or swelling. Intraocular pressure can increase under the influence of steroids. This, in turn, can provoke the development of glaucoma, as well as slow down the healing process. If there is any hint of side effects, Maxitol should be discontinued.

Be sure to check the effect of eye drops on the reaction.

Secondary infections also occur. This occurs after prolonged use. With immune suppression, fungal infections can occur.

It should be used for mild forms of diseases by instillation of one or two drops up to six times a day. If the process is acute and has certain complications, the frequency of taking the remedy increases several times and can be renewed every hour.

Cures for barley on the eye

What is laser coagulation of the retina is described here.

All about Cromoglin drops

Self-medication with this drug is prohibited. Only if the instructions are followed exactly, the medicine can have the desired healing effect. It is released strictly with a prescription, and its use is carried out under the supervision of the attending doctor, this is due to possible serious complications.

Also read about drops such as Pharmadex and Baraplan.