Why do we need female hormones in tablets? About hormone treatment - an obstetrician-gynecologist answers questions.

From previous publications, we know about the abortive effect of hormonal contraceptives (GC, OK). Recently, in the media, you can find reviews of affected women from the side effects of OK, we will give a couple of them at the end of the article. To highlight this issue, we turned to the doctor, who prepared this information for the ABC of Health, and also translated for us fragments of articles with foreign studies on the side effects of HA.

Side effects of hormonal contraceptives.

The actions of hormonal contraceptives, like those of other drugs, are determined by the properties of their constituent substances. Most contraceptive pills prescribed for planned contraception contain 2 types of hormones: one gestagen and one estrogen.

Gestagens

Gestagens = progestogens = progestins- hormones that are produced by the corpus luteum of the ovaries (a formation on the surface of the ovaries that appears after ovulation - the release of the egg), in a small amount - by the adrenal cortex, and during pregnancy - by the placenta. The main progestogen is progesterone.

The name of the hormones reflects their main function - "pro gestation" = "to [preserve] pregnancy" by restructuring the uterine endothelium into a state necessary for the development of a fertilized egg. The physiological effects of gestagens are combined into three main groups.

  1. vegetative effect. It is expressed in the suppression of the proliferation of the endometrium, caused by the action of estrogens, and its secretory transformation, which is very important for a normal menstrual cycle. When pregnancy occurs, gestagens suppress ovulation, lower the tone of the uterus, reducing its excitability and contractility ("protector" of pregnancy). Progestins are responsible for the "maturation" of the mammary glands.
  2. generative action. In small doses, progestins increase the secretion of follicle-stimulating hormone (FSH), which is responsible for the maturation of ovarian follicles and ovulation. In large doses, gestagens block both FSH and LH (luteinizing hormone, which is involved in the synthesis of androgens, and together with FSH provides ovulation and progesterone synthesis). Gestagens affect the center of thermoregulation, which is manifested by an increase in temperature.
  3. General action. Under the influence of gestagens, amine nitrogen in the blood plasma decreases, the excretion of amino acids increases, the separation of gastric juice increases, and the separation of bile slows down.

The composition of oral contraceptives includes various gestagens. For a while it was believed that there was no difference between progestins, but now it is known for sure that the difference in molecular structure provides a variety of effects. In other words, progestogens differ in spectrum and in the severity of additional properties, but the 3 groups of physiological effects described above are inherent in all of them. The characteristics of modern progestins are shown in the table.

Pronounced or very pronounced gestagenic effect common to all progestogens. The gestagenic effect refers to those main groups of properties that were mentioned earlier.

Androgenic activity is not characteristic of many drugs, its result is a decrease in the amount of "good" cholesterol (HDL cholesterol) and an increase in the concentration of "bad" cholesterol (LDL cholesterol). As a result, the risk of atherosclerosis increases. In addition, there are symptoms of virilization (male secondary sexual characteristics).

Explicit antiandrogenic effect available for only three drugs. This effect has a positive meaning - an improvement in the condition of the skin (cosmetic side of the issue).

Antimineralocorticoid activity associated with an increase in diuresis, sodium excretion, and a decrease in blood pressure.

Glucocorticoid effect affects metabolism: there is a decrease in the body's sensitivity to insulin (risk of diabetes), increased synthesis of fatty acids and triglycerides (risk of obesity).

Estrogens

The other ingredient in birth control pills is estrogen.

Estrogens- female sex hormones, which are produced by the ovarian follicles and the adrenal cortex (and in men also by the testicles). There are three main estrogens: estradiol, estriol, and estrone.

Physiological effects of estrogens:

- proliferation (growth) of the endometrium and myometrium according to the type of their hyperplasia and hypertrophy;

- development of genital organs and secondary sexual characteristics (feminization);

- suppression of lactation;

- inhibition of resorption (destruction, resorption) of bone tissue;

- procoagulant action (increased blood clotting);

- an increase in the content of HDL ("good" cholesterol) and triglycerides, a decrease in the amount of LDL ("bad" cholesterol);

- retention of sodium and water in the body (and, as a result, an increase in blood pressure);

- ensuring the acidic environment of the vagina (normally pH 3.8-4.5) and the growth of lactobacilli;

- increased production of antibodies and activity of phagocytes, increased resistance of the body to infections.

Estrogens in oral contraceptives are needed to control the menstrual cycle, they do not take part in protection against unwanted pregnancy. Most often, the composition of the tablets includes ethinylestradiol (EE).

Mechanisms of action of oral contraceptives

So, given the basic properties of gestagens and estrogens, the following mechanisms of action of oral contraceptives can be distinguished:

1) inhibition of the secretion of gonadotropic hormones (due to gestagens);

2) a change in the pH of the vagina to a more acidic side (the effect of estrogens);

3) increased viscosity of cervical mucus (gestagens);

4) the phrase “ovum implantation” used in instructions and manuals, which hides the abortive effect of HA from women.

Gynecologist's commentary on the abortive mechanism of action of hormonal contraceptives

When implanted in the wall of the uterus, the embryo is a multicellular organism (blastocyst). An egg (even a fertilized one) is never implanted. Implantation occurs 5-7 days after fertilization. Therefore, what is called an egg in the instructions is actually not an egg at all, but an embryo.

Unwanted estrogen...

In the course of a thorough study of hormonal contraceptives and their effect on the body, it was concluded that undesirable effects are associated to a greater extent with the influence of estrogens. Therefore, the smaller the amount of estrogens in a tablet, the fewer side effects, but it is not possible to completely eliminate them. It was these conclusions that prompted scientists to invent new, more advanced drugs, and oral contraceptives, in which the amount of the estrogen component was measured in milligrams, were replaced by tablets containing estrogen in micrograms ( 1 milligram [ mg] = 1000 micrograms [ mcg]). There are currently 3 generations of birth control pills. The division into generations is due to both a change in the amount of estrogen in the preparations and the introduction of newer progesterone analogues into the composition of the tablets.

The first generation of contraceptives include "Enovid", "Infekundin", "Bisekurin". These drugs have been widely used since their discovery, but later their androgenic effect was noticed, manifested in the coarsening of the voice, the growth of facial hair (virilization).

Second-generation drugs include Microgenon, Rigevidon, Triregol, Triziston and others.

The most commonly used and widespread are third-generation drugs: Logest, Merisilon, Regulon, Novinet, Diane-35, Zhanin, Yarina and others. A significant advantage of these drugs is their antiandrogenic activity, which is most pronounced in Diane-35.

The study of the properties of estrogens and the conclusion that they are the main source of side effects from the use of hormonal contraceptives led scientists to the idea of ​​​​creating drugs with an optimal reduction in the dose of estrogen in them. It is impossible to completely remove estrogens from the composition, since they play an important role in maintaining a normal menstrual cycle.

In this regard, the division of hormonal contraceptives into high-, low- and microdosed preparations has appeared.

High-dose (EE = 40-50 mcg per tablet).

  • "Non-ovlon"
  • Ovidon and others
  • Not used for contraception.

Low-dose (EE = 30-35 mcg per tablet).

  • Marvelon
  • "Janine"
  • "Yarina"
  • "Femoden"
  • "Diana-35" and others

Microdosed (EE = 20 mcg per tablet)

  • "Logest"
  • Mercilon
  • "Novinet"
  • "Minisiston 20 Fem" "Jess" and others

Side effects of hormonal contraceptives

Side effects from the use of oral contraceptives are always described in detail in the instructions for use.

Since the side effects from the use of various contraceptive pills are approximately the same, it makes sense to consider them, highlighting the main (severe) and less severe ones.

Some manufacturers list conditions that should stop taking immediately. These states include the following:

  1. Arterial hypertension.
  2. Hemolytic-uremic syndrome, manifested by a triad of signs: acute renal failure, hemolytic anemia and thrombocytopenia (decrease in the number of platelets).
  3. Porphyria is a disease in which the synthesis of hemoglobin is impaired.
  4. Hearing loss due to otosclerosis (fixation of the auditory ossicles, which should normally be mobile).

Almost all manufacturers designate thromboembolism as rare or very rare side effects. But this grave condition deserves special attention.

Thromboembolism is the blockage of a blood vessel by a thrombus. This is an acute condition that requires qualified help. Thromboembolism cannot occur out of the blue, it needs special “conditions” - risk factors or existing vascular diseases.

Risk factors for thrombosis (formation of blood clots inside the vessels - thrombi - interfering with the free, laminar blood flow):

- age over 35 years;

- smoking (!);

- high levels of estrogen in the blood (which occurs when taking oral contraceptives);

- increased blood clotting, which is observed with a deficiency of antithrombin III, proteins C and S, dysfibrinogenemia, Marchiafava-Michelli disease;

- trauma and extensive operations in the past;

- venous congestion with a sedentary lifestyle;

- obesity;

- varicose veins of the legs;

- damage to the valvular apparatus of the heart;

- atrial fibrillation, angina pectoris;

- diseases of the cerebral vessels (including transient ischemic attack) or coronary vessels;

- arterial hypertension of moderate or severe degree;

- connective tissue diseases (collagenoses), and primarily systemic lupus erythematosus;

- hereditary predisposition to thrombosis (thrombosis, myocardial infarction, cerebrovascular accident in the closest blood relatives).

If these risk factors are present, a woman taking hormonal contraceptive pills has a significantly increased risk of developing thromboembolism. The risk of thromboembolism increases with thrombosis of any localization, both present and past; with myocardial infarction and stroke.

Thromboembolism, whatever its localization, is a serious complication.

… coronary vessels → myocardial infarction
… brain vessels → stroke
… deep leg veins → trophic ulcers and gangrene
... pulmonary artery (PE) or its branches → from pulmonary infarction to shock
Thromboembolism… ... hepatic vessels → liver dysfunction, Budd-Chiari syndrome
… mesenteric vessels → ischemic bowel disease, intestinal gangrene
... renal vessels
... retinal vessels (retinal vessels)

In addition to thromboembolism, there are other, less severe, but still uncomfortable side effects. For example, candidiasis (thrush). Hormonal contraceptives increase the acidity of the vagina, and in an acidic environment, fungi multiply well, in particular Candidaalbicans, which is an opportunistic pathogen.

A significant side effect is the retention of sodium, and with it water, in the body. This may lead to edema and weight gain. Decreased tolerance to carbohydrates, as a side effect of the use of hormonal pills, increases the risk of diabetes.

Other side effects, such as: decreased mood, mood swings, increased appetite, nausea, stool disorders, satiety, swelling and soreness of the mammary glands, and some others - although they are not severe, however, affect the quality of life of a woman.

In the instructions for the use of hormonal contraceptives, in addition to side effects, contraindications are listed.

Contraceptives without estrogen

Exist gestagen-containing contraceptives ("mini-drank"). In their composition, judging by the name, only gestagen. But this group of drugs has its indications:

- contraception for lactating women (they should not be prescribed estrogen-progestin drugs, because estrogen suppresses lactation);

- prescribed for women who have given birth (because the main mechanism of action of "mini-drank" is the suppression of ovulation, which is undesirable for nulliparous women);

- in late reproductive age;

- in the presence of contraindications to the use of estrogen.

In addition, these drugs also have side effects and contraindications.

Particular attention should be paid to emergency contraception". The composition of such drugs includes either a progestogen (levonorgestrel) or an antiprogestin (mifepristone) in a large dose. The main mechanisms of action of these drugs are inhibition of ovulation, thickening of cervical mucus, acceleration of desquamation (desquamation) of the functional layer of the endometrium in order to prevent the attachment of a fertilized egg. And Mifepristone has an additional effect - an increase in the tone of the uterus. Therefore, a single use of a large dose of these drugs has a very strong simultaneous effect on the ovaries, after taking emergency contraceptive pills, there can be serious and prolonged menstrual irregularities. Women who regularly use these drugs are at great risk to their health.

Foreign studies of side effects of GC

Interesting studies on the side effects of hormonal contraceptives have been carried out in foreign countries. Below are excerpts from several reviews (translation by the author of the article of fragments of foreign articles)

Oral contraceptives and the risk of venous thrombosis

May, 2001

CONCLUSIONS

Hormonal contraception is used by more than 100 million women worldwide. The number of deaths from cardiovascular diseases (venous and arterial) among young, low-risk patients - non-smoking women from 20 to 24 years old - is observed worldwide in the range from 2 to 6 per year per million, depending on the region of residence, the estimated cardiovascular - vascular risk and the volume of screening studies that were carried out before the appointment of contraceptives. While the risk of venous thrombosis is more important in younger patients, the risk of arterial thrombosis is more relevant in older patients. Among older women who smoke and use oral contraceptives, the number of deaths is from 100 to just over 200 per million every year.

Reducing the dose of estrogen reduced the risk of venous thrombosis. Third-generation progestins in combined oral contraceptives have increased the incidence of adverse hemolytic changes and the risk of thrombosis, so they should not be given as first choice in hormonal contraceptive beginners.

Reasonable use of hormonal contraceptives, including avoidance of their use by women who have risk factors, is absent in most cases. In New Zealand, a series of deaths from PE were investigated, and often the cause was an unaccounted for risk by doctors.

Reasonable prescription can prevent arterial thrombosis. Almost all women who had a myocardial infarction while using oral contraceptives were either of an older age group, or smoked, or had other risk factors for arterial disease - in particular, arterial hypertension. Avoidance of oral contraceptives in these women may lead to a reduction in the incidence of arterial thrombosis, as reported by recent studies in industrialized countries. The beneficial effect that third-generation oral contraceptives have on the lipid profile and their role in reducing the number of heart attacks and strokes has not yet been confirmed by control studies.

To avoid venous thrombosis, the doctor asks if the patient has ever had a venous thrombosis in the past, to determine if there are contraindications to prescribing oral contraceptives, and what is the risk of thrombosis while taking hormonal drugs.

Nixodosed progestogen oral contraceptives (first or second generation) caused a lower risk of venous thrombosis than combination drugs; however, the risk in women with a history of thrombosis is not known.

Obesity is considered a risk factor for venous thrombosis, but it is not known whether this risk is increased with oral contraceptive use; thrombosis is uncommon among obese people. Obesity, however, is not considered a contraindication to oral contraceptive use. Superficial varicose veins are not a consequence of pre-existing venous thrombosis or a risk factor for deep venous thrombosis.

Heredity may play a role in the development of venous thrombosis, but its tangibility as a high risk factor remains unclear. Superficial thrombophlebitis in history can also be considered as a risk factor for thrombosis, especially if it is combined with aggravated heredity.

Venous thromboembolism and hormonal contraception

Royal College of Obstetricians and Gynecologists, UK

July, 2010

Do combined hormonal contraceptive methods (pills, patch, vaginal ring) increase the risk of venous thromboembolism?

The relative risk of venous thromboembolism increases with the use of any combined hormonal contraceptive (pills, patch and vaginal ring). However, the rarity of venous thromboembolism in women of reproductive age means that the absolute risk remains low.

The relative risk of venous thromboembolism increases in the first few months after starting combined hormonal contraception. As the duration of taking hormonal contraceptives increases, the risk decreases, but as a background it remains until the cessation of the use of hormonal drugs.

In this table, the researchers compared the incidence of venous thromboembolism per year in different groups of women (in terms of 100,000 women). From the table it is clear that in non-pregnant women and women not using hormonal contraceptives (non-pregnantnon-users), an average of 44 (with a range of 24 to 73) cases of thromboembolism per 100,000 women are registered per year.

Drospirenone-containingCOCusers - users of drospirenone-containing COCs.

Levonorgestrel-containingCOCusers - using levonorgestrel-containing COCs.

Other COCs not specified - other COCs.

Pregnantnon-users are pregnant women.

Strokes and heart attacks while using hormonal contraception

"New England Journal of Medicine"

Medical Society of Massachusetts, USA

June, 2012

CONCLUSIONS

Although the absolute risks of stroke and heart attack associated with hormonal contraceptives are low, the risk was increased from 0.9 to 1.7 with drugs containing ethinylestradiol at a dose of 20 mcg and from 1.2 to 2.3 with the use of drugs containing ethinyl estradiol at a dose of 30-40 mcg, with a relatively small risk difference depending on the type of gestagen included.

Risk of thrombosis of oral contraception

WoltersKluwerHealth is a leading provider of qualified health information.

HenneloreRott - German doctor

August, 2012

CONCLUSIONS

Different combined oral contraceptives (COCs) are characterized by a different risk of venous thromboembolism, but the same unsafe use.

COCs with levonorgestrel or norethisterone (the so-called second generation) should be the drugs of choice, as recommended by national contraceptive guidelines in the Netherlands, Belgium, Denmark, Norway and the UK. Other European countries do not have such guidelines, but they are essential.

In women with a history of venous thromboembolism and/or with known defects in the blood coagulation system, the use of COCs and other contraceptive preparations with ethinyl estradiol is contraindicated. On the other hand, the risk of venous thromboembolism during pregnancy and the postpartum period is much higher. For this reason, such women should be offered adequate contraception.

There is no reason to abstain from hormonal contraception in young patients with thrombophilia. Progesterone-only preparations are safe in relation to the risk of venous thromboembolism.

Risk of venous thromboembolism among users of drospirenone-containing oral contraceptives

American College of Obstetricians and Gynecologists

November 2012

CONCLUSIONS
The risk of venous thromboembolism is increased among users of oral contraceptives (3-9/10,000 women per year) compared with non-pregnant and non-users of these drugs (1-5/10,000 women per year). There is evidence that drospirenone-containing oral contraceptives have a higher risk (10.22/10,000) than drugs containing other progestins. However, the risk is still low and much lower than during pregnancy (approximately 5–20/10,000 women per year) and postpartum (40–65/10,000 women per year) (see table).

Tab. risk of thromboembolism.

What is not said about hormonal drugs. Some attribute miraculous properties to them, others scare them with terrible effects. Where are the myths and where is the reality?

Hormones are substances that have biological activity. In the human body, they are synthesized by the endocrine glands. Released into the blood, hormones spread throughout the body and have a regulatory effect on its physiological processes and metabolism. This ensures a balanced and stable functioning of the body. There are many hormones and each has its own specific effect. Therefore, it is not entirely correct to speak indiscriminately about the influence of all hormones in general. Nevertheless, let's try to clarify the most established statements about hormones.

Myth 1. If hormones are prescribed, then the disease is very serious.
It is not always so. Hormonal preparations treat both severe diseases and not so much. They are even prescribed to perfectly healthy people, for example, to prevent unwanted pregnancies. It is not necessary to judge the severity of your condition by the prescribed treatment. This question is best always clarified in an open conversation with your doctor.

Myth 2. Side effects appear even with short-term use of hormones.
It is not true. Hormones do not have toxicity, therefore, even in large doses, poisoning of the body will not occur. The occurrence of side effects is not related to the dose of the drug. They occur with frequent and prolonged use of hormones, even if the dose taken is scanty. And the longer the reception, the greater the severity of these effects. Therefore, doctors quite often practice the so-called “pulse therapy” with hormones, when high doses are prescribed for a short time.

Myth 3. If you take hormones in small doses, then there will be no particular harm.
Wrong. Hormones affect the human body in any dose. At the same time, in a small amount, the effect can be one, and in a large amount it is completely different, even directly opposite. Therefore, hormonal preparations should be taken only as prescribed by a doctor and only in those doses prescribed by a doctor. Self-medication in the case of hormones can not only not lead to the desired result, but also end badly.

Myth 4. Hormones make you fat.
Yes and no. It all depends on which hormones we are talking about. For example, with prolonged use of glucocorticosteroids, changes in body weight can be observed. And when taking thyroxine, on the contrary, you can lose in kilograms. In most cases, with properly selected doses of hormonal drugs, body weight does not undergo changes directly from the influence of hormones.

Myth 5. After taking hormones, mustaches begin to grow in women, and breasts in men.
Yes and no. It all depends on what specific hormones a person takes. For example, with prolonged use of glucocorticosteroids, such side effects may occur. True, the breasts in men increase due to obesity. The use of insulin will never lead to such an effect.

Myth 6. It is very dangerous to take hormones at a young age.
Wrong. In some cases, hormones can save a person's life. And it does not depend on age. With an attack of bronchial asthma or a severe allergic reaction, only the introduction of hormones can stop the pathological process and reverse it.

Myth 7. All hormonal contraceptives are the same.
This is not true. Different drugs contain different amounts and ratios of progestin and estrogen. In addition, there may be variations in the chemical composition of the components. This allows you to more accurately select the optimal drug for each woman individually with the maximum contraceptive effect and minimal side effects.

Myth 8. Hormones can be drunk irregularly, from time to time, it's not scary to miss a dose.
Not true. Hormonal drugs should be taken only according to the prescribed scheme and even by the hour. Otherwise, the hormonal background will fluctuate dramatically, which will not lead to the desired therapeutic effect, and may also adversely affect the health and course of the disease. For example, if insulin is not taken on time, the risk of coma with an unfavorable outcome increases.

Myth 9. Gradually, the body gets used to taking hormones.
To some extent this is true. If you take a hormonal drug for a long time, then your own glands begin to produce this hormone in smaller and smaller quantities. That is why doctors periodically prescribe periods of "rest" from a hormonal drug during long-term therapy.

Myth 10. Any hormone can be replaced by other drugs.
Most often this is not the case. For example, with a completely removed thyroid gland, it is necessary to take preparations of its hormones throughout life, and there is no alternative. The situation is similar with diabetes mellitus, when a person cannot live without insulin.

If the doctor prescribes you a hormonal drug, you do not need to be afraid of unpredictable consequences. Find out from the doctor all the incomprehensible moments, ask all the questions that concern you. Only with full confidence in the doctor and the treatment prescribed by him, you can achieve the maximum result.

The word "hormones" causes fear in 60% of modern women. This fact is not surprising: hormone therapy is indeed quite a serious and often not harmless therapeutic measure. The dangers of hormonal drugs are often and much spoken about, while their benefits are rarely remembered. But few people think that hormonal therapy can significantly improve the quality of human life, and sometimes even support this very life (for diabetes, thyroid disease, bronchial asthma, etc.).

Are hormone pills harmful?

As the hormone hormone discord, and hormonal agents differ in the degree of positive and negative effects on the body. The ratio of harm and benefit of hormonal drugs is determined by the type of hormone, its concentration, frequency, duration and method of application.

Yes, of course, hormonal drugs do some harm to the body. But, as a rule, they do not cause more damage to health than the disease for which this drug is used. Today, there are diseases that cannot be treated without hormones.

Why are hormonal drugs harmful?

It must be clearly understood that hormonal drugs of the 21st century cannot be compared with hormonal drugs of the 20th century. If our mothers associated the phrase “hormonal treatment” with excess weight, edema, unnatural hair growth, then in our time such side effects are minimized. But it is important to understand that the harm from the use of a hormonal drug will be minimal only if it is properly selected.

So, why are hormonal drugs harmful? To answer this question, you just need to read the instructions for use for a particular tool. In the "Side Effects" section, as a rule, the whole range of possible (but not mandatory) side effects is indicated, among them are the classic ones: metabolic disorders, weight gain, excessive hair growth, skin rashes, disruption of the gastrointestinal tract, and more.

The harm and benefits of hormonal contraceptives

Hormone therapy in women most often involves treatment with oral contraceptives (OCs), the main purpose of which is contraception, and the therapeutic effect is achieved as a positive side effect. Discussions about the benefits and harms of hormonal contraceptives have been going on for many years.

Some theorists and practitioners of medicine, including alternative medicine, are categorically against the use of hormonal contraceptives in medical practice, since they cause irreparable harm to the female body in the form of: suppression of ovarian function, changes in the natural background of a woman, dangerous side effects.

Another part of the experts claims, and numerous scientific studies confirm that everything written above has nothing to do with modern OK. Huge doses of hormones, which were contained in the hormonal preparations of the first generations, caused serious harm to the female body. Improved OK of the new generation are characterized by a mild effect on due to the maximum cleansing and the minimum quantitative content of the hormone. Against the background of OK reception:

The benefit-to-risk ratio for hormonal contraceptive pills is unambiguously positive.

And to the frequent question of women: “How harmful are hormonal pills?” the following answer can be given: in the absence of contraindications, subject to the correct diagnosis and the correct selection of the drug - practically nothing. The first three months of admission (the period of adaptation to the drug) side effects are possible: nausea, headaches and dizziness, breast engorgement, mood swings, decreased sexual desire.


I have a lot of examples when, after the cancellation of OK, the menstrual cycle did not start in women, because the ovaries forgot how to work.

Here I was disappointed and had to remember what condoms are. Then psychosis, depression, tearfulness began (I wake up and roar at night), fears and panic (in two weeks I redid the ultrasound of all organs, I’m looking for cancer), terrible headaches, I walk with red tearful eyes, nausea. Melodramas about love began to cause touching squelching in the cynical me. Estrogens in oral contraceptives are needed to control the menstrual cycle, they do not take part in protection against unwanted pregnancy. But unfortunately the story does not end there. A sharp refusal to take hormonal pills is justified only in cases where side effects are observed: high blood pressure, headache, bleeding, dizziness, etc. The other ingredient in birth control pills is estrogen. Yes, I thought I was the only one. kapets what they do OK with the body After the birth of the second daughter and how she stopped breastfeeding, she inserted a novaring ring for herself.

The period of restoration of the menstrual cycle of the female body after the abolition of birth control pills has occurred depends on the following factors: Which drug was taken (high-hormonal or low-hormonal). Previously, doctors advised taking a break of 3-4 months after 2 years of using the drug. The doctor said that since I have no complaints and outwardly noticeable problems, tests for hormones would be a waste of money. There was an operation, but two years after the birth of the child, the cysts reappeared and with varying success I fought them (compresses with sea salt, gels, herbs, drops), plus signs of endometriosis appeared, the struggle continued until the gynecologist advised me to drink Lindinet 20 hormones, over time, the cysts resolved themselves, endometriosis dissolved like a morning dream. Switch to another type of contraceptive. All the more that on the sly began to think about the birth of a child.

Stopped drinking hormones consequences: in more detail

I drank it for 3 months, as soon as I canceled it, then all my problems began, namely panic attacks, hot flashes, a decrease and increase in pressure, weight loss, immunity, terrible depression, there was hell in my soul, indifference to everyone and everything. Dropped Jess. And what do you think? Diagnosis: head venous thrombosis. Therefore, think a hundred times before taking pills. Thrombosis Risk of Oral ContraceptionWoltersKluwerHealth is a leading provider of expert health information.

If, after six months from the day when the woman stopped taking hormonal pills, menstruation did not come, she should definitely consult a doctor. In a few months I will think about how to get off the antidep-ta, one pulls the other. She was operated on right away. The story happened 5 years ago when I was 36 years old. I know there are a lot of people like me, but I haven’t given birth yet, I’m 25, and I want a baby.

And they send me to hospitals, they only say that I didn’t eat right, that I had an inactive lifestyle (although before that I was active) I don’t know, maybe I already have problems with blood clots ... And my face is all covered with terrible acne, my skin became flabby and Stretch marks everywhere from legs to belly! Hair falls out, but where it is not necessary they grow. Please write what kind of product it is. It is better not to start taking any hormonal. In their composition, judging by the name, only gestagen. I got pregnant as planned, it was the third birth. the pregnancy was excellent, but there were problems with childbirth, the cervix did not open more than 4 cm, thanks to the doctor, I rushed off but gave birth. Vaginal discharge and others.

I'll go to the gynecologist, maybe I'll change OK. Physiological effects of estrogens: proliferation (growth) of the endometrium and myometrium according to the type of their hyperplasia and hypertrophy; development of genital organs and secondary sexual characteristics (feminization); suppression of lactation; inhibition of resorption (destruction, resorption) of bone tissue; procoagulant action (increased blood clotting);

Stopped drinking hormones consequences: what you did not know

increasing the content of HDL (“useful” cholesterol) and triglycerides, lowering the amount of LDL ("bad" cholesterol); retention of sodium and water in the body (and, as a result, an increase in blood pressure); ensuring the acidic environment of the vagina (normally pH 3.8-4.5) and the growth of lactobacilli; enhancing the production of antibodies and the activity of phagocytes, increasing the body's resistance to infections. Porphyria is a disease in which the synthesis of hemoglobin is impaired. WHY DOES NO ONE TELL US ABOUT THIS. My name is Anya, I'm 21. In some cases, there may be copious discharge. By the end of the fourth week, desperate to wait for PMS, I took a pregnancy test. Spotting begins no earlier than 21 days after the start of the course of contraceptives. The third week I passed, all the time something humming under my breath, smiling at passers-by and making devastating raids on the refrigerator. But this group of drugs has its indications:

how to stop drinking hormonal contraceptives (video on the topic)


contraception for lactating women (they should not be prescribed estrogen-progestin drugs, because estrogen suppresses lactation); prescribed for women who have given birth (because the main mechanism of action of "mini-drank" is the suppression of ovulation, which is undesirable for nulliparous women); in late reproductive age; in the presence of contraindications to the use of estrogen.

But my dislike for OK is persistent. I also took Diana-35 for 5 months. I only drank 5 because the weight started to increase. If birth control pills were prescribed to correct the hormonal background, then a blood test for the concentration of sex hormones will definitely be required. Hormonal contraceptives increase the acidity of the vagina, and in an acidic environment, fungi, in particular Candida albicans, multiply well. which is an opportunistic pathogen. Mechanisms of action of oral contraceptives

So, given the basic properties of gestagens and estrogens, the following mechanisms of action of oral contraceptives can be distinguished: 1) inhibition of the secretion of gonadotropic hormones (due to gestagens); 2) a change in the pH of the vagina to a more acidic side (the effect of estrogens); gestagens); 4) the phrase ovum implantation used in instructions and manuals, which hides the abortive effect of HA from women. Here someone wrote that you need to wait until the hormone leaves the body Complete nonsense, the hormone leaves after 24 hours and there is no trace. Microdosed (EE = 20 mcg per tablet)

Side effects of hormonal contraceptives Side effects from the use of oral contraceptives are always described in detail in the instructions for use. There are currently 3 generations of birth control pills. And Mifepristone has an additional effect - an increase in the tone of the uterus. Well, who believes in those terrible side effects on the wrapper? In general, after 6 months severe headaches began. As a result, I canceled Yarina, dizziness passed, menstruation came after 1 month. But my body is still feverish (4 months have passed): immunity fails, tearfulness, irritability, fatigue, muscle weakness. Now I will be treated surgically and will try never to take hormones again. All are alive and well.

I quit drinking birth control pills consequences (video on the topic)


For some, they even stop for a certain period. A friend of mine recently, really scared that OK causes a decrease in sexual activity in women, I hope this is just stupid gossip!) Girl, try to cancel them and you will understand what people are talking about while you drink, everything is fine, all these horrors begin after cancellation. I began to paint lips and eyelashes, and even bought a couple of new lipsticks, which I had not done for five years. While the risk of venous thrombosis is more important in younger patients, the risk of arterial thrombosis is more relevant in older patients. For a while it was believed that there was no difference between progestins, but now it is known for sure that the difference in molecular structure provides a variety of effects. My emotions and reactions changed so much that I didn't recognize myself. Venous thromboembolism and hormonal contraceptionRoyal College of Obstetricians and Gynecologists, UK Do combined hormonal contraceptive methods (pills, patch, vaginal ring) increase the risk of venous thromboembolism?

The relative risk of venous thromboembolism increases with the use of any combined hormonal contraceptive (pills, patch and vaginal ring). Nixodosed progestogen oral contraceptives (first or second generation) caused a lower risk of venous thrombosis than combination drugs; however, the risk in women with a history of thrombosis is not known. Levonorgestrel-containingCOCusers - using levonorgestrel-containing COCs. Recommended by a qualified gynecologist. It was these conclusions that prompted scientists to invent new, more advanced drugs, and oral contraceptives, in which the amount of the estrogen component was measured in milligrams, were replaced by tablets with estrogen content in micrograms (1 milligram [mg] = 1000 micrograms [mcg]). Doctors diagnosed rheumatoid arthritis! They began to treat everything, but the disease progressed. Frequent colds because immunity has fallen. But recently I began to swell and the lymph nodes are swollen all over my body.

And now, almost a year has passed, but there is no baby, it doesn’t work out. I have been on contraceptives for 10 years. 8 years took Diana35, 2 years on Belar.

Finish the started pack. I just constantly replay in my head the moment when I opened a pack of Jess and drank the first pill and dreamed of returning the past ... I write and sob excitedly, because there are already some forces and no money for recovery. The first month was addictive from 8 to 18 smeared, when the placebo went, my head started to hurt terribly. Gynecologist's commentary on the abortive mechanism of action of hormonal contraceptives When implanted in the uterine wall, the embryo is a multicellular organism (blastocyst). And you can't for the rest of your life.

But the gynecologist said that contraception does not affect the immune system. I have a lot of examples when, after canceling OK, there are no changes in the body. I'm tired of going to hospitals. In addition, these drugs also have side effects and contraindications.

They are able to disrupt the normal physiology of the gonads, as well as the stability of the female monthly cycle, thus causing unpleasant consequences. And there is the drug alprazolam, which is prescribed by a psychiatrist. What are the consequences? ”During or after taking oral contraceptives, the lower abdomen, chest, head, eyes, etc. may hurt. As a result, antidepressants, and these are also not vitamins ADah you understand a lot and you start solving and moving many problems. Before marriage, she also drank Femoden, after the abolition of any side effects, the cycle immediately recovered, all pregnancies are normal. When I came to the doctor with a request to pick up pills for me, they did a full set of tests, except for hormonal ones. If a girl has just started taking birth control pills, her lower abdomen can be very sore, monthly bleeding can linger, etc. And I have a son. A friend said that his wife, having stopped taking pills, became a different person - livelier, more open, more feminine, and recovered! A doctor friend explained that there is practically no research on the effect of hormonal contraceptives on the emotional background, and even a full range of hormone tests will not give any guarantee of your emotional safety, and doctors most often simply dismiss questions and complaints about this topic. I understand that what has been done cannot be returned, I now have only one question how to get out of these states. how to raise health now, I know that it is simply necessary to fight for life.

And every day something hurts, then your heart will stab, then your lower back, then your head will hurt or feel sick. Estrogens are female sex hormones that are produced by the ovarian follicles and the adrenal cortex (and, in men, also by the testicles). Therefore, a single use of a large dose of these drugs has a very strong simultaneous effect on the ovaries, after taking emergency contraceptive pills, there can be serious and prolonged menstrual irregularities. However, the rarity of venous thromboembolism in women of reproductive age means that the absolute risk remains low. We will give you some simple tips. Obesity, however, is not considered a contraindication to oral contraceptive use. Heredity may play a role in the development of venous thrombosis, but its tangibility as a high risk factor remains unclear. The husband was unable to work. Compared to previous experiences, I was noticeably worse, especially on the first day. Before pregnancy, only a genetic examination was carried out and 2 polyps were found on the cervix.

When a woman has made the decision to stop taking oral contraceptives, she should do the following: 1. Do not despair. Everything is being treated. I hope my article will help someone. Health to you. The doctor says that everything is serious, a heart attack is close and they can’t understand what affects, they sent him to an endocrinologist - everything is in order, to a neuropathologist - she appointed her examination, but she is silent about heart attacks. The glucocorticoid effect affects metabolism: there is a decrease in the body's sensitivity to insulin (the risk of diabetes), an increase in the synthesis of fatty acids and triglycerides (the risk of obesity). After all, the body is used to them, and the cancellation is sharp. Health is excellent, apart from problems with the spine, but this is family and has nothing to do with contraceptives. So girls, if you are prescribed hormones, ask them to do hormone tests and select them individually, and not what they advertise in advertisements and magazines, and drink vitamins, and PANANGIN is MANDATORY.

Hormonal contraceptives are a business that cripples. (video on the topic)


The girls will be attentive and for your nonsense, I listened to the doctor. It was only after reading the reviews that I now wondered what would happen after the cancellation. And for several days in a row, an unreasonable increase in pressure to 150/110 mm Hg. (no stress or other precipitating factors). My friend went to the gynecologist, she told her to immediately stop drinking them, because they are deadly! I decided to stop drinking too, linking all my ailments with jess! What is happening right now is horrendous. It was a plus.

Side effects of hormonal contraceptives. For example, candidiasis (thrush). It's all due to hormonal contraceptives. After the wedding, they decided to give birth to a child, the drug had to be canceled for menstruation, it seemed hard labor, but I had to endure it. There are three main estrogens: estradiol, estriol, and estrone.

Reasonable prescription can prevent arterial thrombosis. Through the failure of hormonal indicators in the body. It is strange to read that someone is going to jump out of the window because of contraceptives. Every day something hurts somewhere. I worked as a chief accountant. I was in constant stress from inspections, so I didn’t pay much attention. but it didn't end there. As soon as I started taking Yarina, everything changed. By the way, I still doubt that hormone tests would save me from those nuances that arose over time. I drink Yarina for a year. Antimineralocorticoid activity is associated with an increase in diuresis, sodium excretion, and a decrease in blood pressure.

We need to somehow hold out for another two months. Girls without tests for hormones, don’t drink anything on the advice, believe me, I’m afraid, now I’m afraid that it will only get worse after cancellation (((support me! Maybe someone drank a boron uterus later?

Her grandmother, the sorceress, prescribed it to me even before I started taking these ok. Usually such patients are treated with hormones, you can’t see me. The situation was saved by a colleague who, counting on her fingers, suggested that I was ovulating. If these risk factors are present, a woman taking hormonal contraceptive pills has a significantly increased risk of developing thromboembolism. A few days later, I fainted on the subway.

In this table, the researchers compared the incidence of venous thromboembolism per year in different groups of women (in terms of 100,000 women). Getting better. Hemolytic-uremic syndrome, manifested by a triad of signs: acute renal failure, hemolytic anemia and thrombocytopenia (decrease in the number of platelets). Delayed bleeding can be caused by a sudden change in a woman's weight. I started using it at the age of 18.

Later, shortness of breath and tachycardia, mood swings, headaches, eternal fatigue and a constant desire to sleep began. Eventually. despite all the difficulties, I like it more. Drospirenone-containingCOCusers - users of drospirenone-containing COCs.

Change of mood. And of course I wish you to find a good gynecologist. For this reason, such women should be offered adequate contraception. My opinion is that ok just provoke an already existing neurosis and deeply driven depression. Immunity is normal. Further, the attending physician will develop an optimal scheme for refusing to take oral contraceptives.

Before that, she was a healthy person, happy and very beautiful. To avoid venous thrombosis, the doctor asks if the patient has ever had a venous thrombosis in the past, to determine if there are contraindications to prescribing oral contraceptives, and what is the risk of thrombosis while taking hormonal drugs. Particular attention should be paid to emergency contraception. Physiologically, it is possible to get pregnant after birth control pills a month after the end of their intake. In some situations, this can take up to several months. Went happy as an elephant.

The risk of thromboembolism increases with thrombosis of any localization, both present and past; with myocardial infarction and stroke. Masked depression, senestopathy and other charms Whom I just didn’t, in the end, of course, ended up with a psychotherapist. In the end, it is better to give birth to a bunch of children than to suffer the rest of your life later. And now more than 180/110 and pulse up to 167. This is especially important for those who are planning a pregnancy. Before that, there were three pregnancies, one ended in childbirth. Keep alive.

There are a bunch of other contraceptives. Doctors can't tell why I'm swollen and why my veins hurt, especially on my left arm, part of my head and legs. I just can’t exist like this anymore ... Hello girls! I have read your reviews! I myself drank jess for about 2.5 years! In principle, everything suited me, but my immunity was greatly reduced, my temperature was constantly 37.4, and before that I was very healthy, no illness could break me! I felt terrible, but I couldn't connect it with Jess.

There were delays of up to 3 months. Therefore, the smaller the amount of estrogens in a tablet, the fewer side effects, but it is not possible to completely eliminate them. Describing what happened to me is terrible. The consequences of long-term use of hormonal pillsMany women are interested in how many years you can take birth control so as not to harm your reproductive system. As a result, gastritis, pancreatitis, disorders of the kidneys and liver, VVD are put in hospitals when they bring me blue and with chills.

People who read your post may believe that the contraceptive is safe, but it is not. But now this advice is considered highly controversial, because after the studies it has become clear that the break causes stress for the body. If the menstruation came earlier, this indicates an insufficiently high level of the hormone in the tablets, which are not able to cause the ovaries to stop secreting estrogen. In this regard, the division of hormonal contraceptives into high-, low- and microdosed preparations has appeared. Gestagens \u003d progestogens \u003d progestins - hormones that are produced by the corpus luteum of the ovaries (a formation on the surface of the ovaries that appears after ovulation - the release of the egg), in a small amount - by the adrenal cortex, and during pregnancy - by the placenta. The tea smelled of perfume, the sausage smelled of herring, the coffee smelled of gasoline. Second-generation drugs include Microgenon, Rigevidon, Triregol, Triziston and others. Sometimes heavy bleeding may occur while taking contraceptives, which indicates a decrease in the level of the hormone, but this is the norm in the first two cycles from the start of taking the pills.

The pain was hellish, I even had to drink ketanov and no-shpu, which I did not do all those years that I was on pills. When pregnancy occurs, gestagens suppress ovulation, lower the tone of the uterus, reducing its excitability and contractility ("protector" of pregnancy). The age of the woman taking these drugs.

I do not recommend. By the way, a colleague, who herself has recently been on pills, scared me a lot, dreamily stretching out: Oh, well, now you will have PMS. Dizziness, depression, etc. In 2013, after consulting a doctor, I started taking these pills. Terribly tired of hospitals, calling an ambulance 2 times a week, and most importantly, no one can help, they just prescribe pills for blood pressure and that's it. High-dose (EE = 40-50 mcg per tablet). And she prescribed me the newest and lightest pills at that time.

I quit drinking jess consequences (video on the topic)


The actions of hormonal contraceptives, like those of other drugs, are determined by the properties of their constituent substances. On the other hand, the risk of venous thromboembolism during pregnancy and the postpartum period is much higher. I have a young man, I love him and he is fighting for my life, but in all clinics they tell me that this is because of my nerves. Among older women who smoke and use oral contraceptives, the number of deaths is from 100 to just over 200 per million every year. Menstruation after birth control Women often ask the question: “I stopped drinking birth control, which periods are considered normal in this case?” Sometimes, after the abolition of contraceptives, there is a delay in menstruation, or the discharge appears very scarce, or they are not at all. Now I'm being treated by a neurologist, I'm sitting on tranquilizers. But Yarina broke me: endless pyelonephritis (high white blood cells in the tests), cystitis, depression, panic attacks, decreased immunity, pain in the lower back and sides, etc. The gynecologist did not believe in my complaints, but I myself already realized that the matter was ok.

After examination by a cardiologist, the diagnosis was ventricular exasistolia (arrhythmia), the heart beats at a frequency of 43 beats per minute to 186 beats. For the general condition, I can’t say anything because I didn’t have time to watch it. I failed for 2 weeks in the trombone department with grannies over 70-80, after which I took coumadin for a year and donated blood once a week. saw diana-35 6 months, skin, hair, chest, cycle everything was perfect. Now the doctor says start taking Chloe, he supposedly will help. The main progestogen is progesterone. I have other results! She suffered from painful periods up to loss of consciousness, and then a cyst was found on the right ovary, the cycle was not regular.

When I finished taking Jez, a ball appeared on my leg above the knee, it slowly grew, it didn’t really bother me, but I wanted to remove it during pregnancy, the doctor didn’t allow it. 4 months after the birth, I was operated on, I thought it was all over, but I was wrong . came the histology of this formation MELANOMA! Now I don’t know what to do, where to run and how much I have left. Reasonable use of hormonal contraceptives, including avoidance of their use by women who have risk factors, is absent in most cases. Hi girls, after this article I decided to stop drinking hormones, I have had heartburn for a month now, hemoglobin is elevated, my head hurts, even if only the ovary hurts better than a whole bouquet!

Saw Logest 1.5 years old, had endometriosis, turned into left-sided adnexitis and adhesions, there was a break in the summer, but they said that I still need to drink, damn it, I can’t anymore, well, nafik, now I need to treat the stomach and pancreatic colitis It all started after childbirth, thank you God has a son. Recently discovered endometriosis. I became much more feminine, calmer and softer, as if I made friends with myself, from the inside. Depression, I can connect with the beginning of taking the drugs, but not with the end. In my opinion, birth control is the most reliable contraception.

I also look at Remens or Cyclodinone, all the same, these drugs are herbal. A significant advantage of these drugs is their antiandrogenic activity, which is most pronounced in Diane-35. At first everything was fine, painless menstruation, clean skin, breasts a size larger .. after about 2 years I took a break for a month, acne appeared, which I never had, menstruation did not occur for 3 months, I had to call, and then take Chloe again by recommendation doctor for the time of admission there were several terrible things: firstly, terrible headaches for several months, and secondly, I woke up from a strong sharp pain in my right ovary, I barely crawled to the bathroom, my face was yellow-blue, vomiting and unbearable pain, as if the ovary had burst ( as a result, it turned out for a snake that an egg cell made its way through the oppressed ovaries and ruptured a blood vessel.

Now I’m taking vitamins Lavita and haven’t changed OK for half a year) My hair also got better, my skin cleared up and in general the state of the body became better)) For a year I drank 3 types of hormones due to ovarian endometriosis (before that, I drank Yarina 5 years ago, after adaptation there was no period of side effects, after the abolition, the condition of the hair and skin worsened for a while: first, duphaston (to make sure that the cyst was not functional), then janin, then yarin. All these symptoms have not gone away so far. Girls! Be especially careful if you have a history of VVD and varicose veins. Thromboembolism, whatever its localization, is a serious complication. And after adaptation, the woman again begins to drink pills, thereby causing a reverse restructuring of the endocrine system. All attempts to reduce it were absolutely unsuccessful: 5 kg will go away, so 8 will be typed. And there is nothing to worry about. The second attempt was much more curious.

Hello Anastasia. The general health of the woman. The result is pancreatitis. Menstruation did not start, but the gynecologist advised me to give injections that include the ovaries. From this article, you will learn how to properly refuse hormonal pills without harm to health. And it seems that everything began to stabilize, but only the cycle became either a week earlier or 10 days later. God forbid you experience this. After a week of insomnia, I still called an ambulance. I've been suffering for four years and I can't do anything about it.

Although perhaps all individually. It's been like this for a whole month, the pressure is constantly increased, a lot of tests and everything is also relatively normal. The first generation of contraceptives include "Enovid", "Infekundin", "Bisekurin". Gestagens affect the center of thermoregulation, which is manifested by an increase in temperature. But doctors recommend not to rush and wait at least three months. After canceling due to problems with the intestines, she went on a diet, as a result, she lost 4 kg in a month. By the sixth week, it dawned on me. Now they will need some time to tune in to the desired mode of operation.

No panic attacks or mood changes. When, while taking medical contraceptives, there is a delay in menstruation, the lower abdomen hurts, nausea, dizziness is observed - take a pregnancy test. Although it doesn't sound like me, I've always been an optimist!

In general, I curse these tablets, I save myself with only one product that stabilizes the hormonal background and which is completely natural! Slowly recovering, there are improvements! Girls, I read the reviews, it's terrible, don't think about suicide! I can only recommend the product that I drink Hello!

You need to check your head and go to a psychiatrist, and not sin on contraceptives. God forbid everything will work out for everyone who has encountered problems after taking contraceptives. Strokes and heart attacks when using hormonal contraception"Medical Journal of the New England»

I quit drinking Jeanine the consequences (video on the topic)


Massachusetts Medical Society, USA Although the absolute risks of stroke and heart attack associated with hormonal contraceptives are low, the risk was increased from 0.9 to 1.7 with drugs containing ethinyl estradiol at a dose of 20 mcg and from 1.2 to 2 ,3 - when using drugs containing ethinyl estradiol at a dose of 30-40 mcg, with a relatively small risk difference depending on the type of gestagen included. On the contrary, I was overwhelmed by tenderness for the world around me and complete harmony with myself.

As the duration of taking hormonal contraceptives increases, the risk decreases, but as a background it remains until the cessation of the use of hormonal drugs. The composition of such drugs includes either a progestogen (levonorgestrel) or an antiprogestin (mifepristone) in a large dose. To prevent this, you need to contact a gynecologist as soon as a long delay has begun. A significant side effect is the retention of sodium, and with it water, in the body. I will cancel the drug. I quit drinking hormones, now I have not had my period for three months.

It would seem that platelets should rise, but I have the opposite, I take an analysis from Vienna and the blood stops only after an hour. about using the GK Hello girls! for 2 years I have been on a variety of hormonal: injections of Zoladex, Jeanine, Duphaston, Novinet, Nova Ring. In other words, progestogens differ in spectrum and in the severity of additional properties, but the 3 groups of physiological effects described above are inherent in all of them. As a result, the cycle was restored, I became pregnant for 3 cycles after the cancellation. And only 1 out of 10 who stopped taking contraceptives will not be able to get pregnant over the next year. But in order to avoid problems, she should be examined twice a year by a gynecologist and once by a mammologist. To highlight this issue, we turned to the doctor who prepared this information for the ABC of Health. and also translated for us fragments of articles with foreign studies of side effects of HA. Hearing loss due to otosclerosis (fixation of the auditory ossicles, which should normally be mobile).

Women who regularly use these drugs are at great risk to their health. In New Zealand, a series of deaths from PE were investigated, and often the cause was an unaccounted for risk by doctors. Some manufacturers list conditions that should stop taking immediately. I began to take these pills on the advice of a gynecologist about alopecia and endometriosis of the cervix. I definitely won’t drink the third package, it’s not worth it! Vegetative manifestations are just terrible shortness of breath, there is tachycardia, some kind of hot flashes, you feel like a grandmother in menopause. Either drink them all your life, or don't drink them.

But, by the way, it is better to drink a course of vitamins along with OK. I'm buying a women's complex "Lavita". Thank God, now there are two kids. Hello! I am also one of those affected by OK. As a result, the risk of atherosclerosis increases. Prescribed jess. Health is excellent, apart from problems with the spine, but this is family and has nothing to do with contraceptives. A rash appeared on my face, I thought it was due to nerves or an allergy to drugs, the tests danced, showing either positive tumor markers or the norm! Probably only my husband knows what we had to endure!

In general, with a non-falling temperature of 39, pain in the joints and throughout the body, I was taken to Orenburg to the rheumatology department, and there they finally made the correct diagnosis of SLE. After the 9th tablet with attacks of terrible suffocation, numbness of the limbs, and a complete lack of normal consciousness, 2 times within an hour, the husband and parents brought to the ambulance. I spent a whole month in the hospital on antidepressants, it became easier, I gained weight, my mood improved. To be honest, in one of them I noticed the same stiffness. We decided to have a second child. Oh, girls, I read and shed tears. 6 years ago I thought. that against the background of hormones insomnia and depression. I wanted it always and everywhere. But then my gynecologist advised me to take some other vitamins along with OK, because with them the side effects from OK will decrease to a minimum. I'm trying to get myself under control, but it doesn't quite work.

So, what is next? With these pills, at least my endometrium stopped falling off in pieces and the cycle was adjusted, but my heart and nerves are just to hell. I did not understand at all what was happening to me, and even panicked a little, as if, having thrown the pills, I had forgotten how to think. "Climbing" off hormonal pills: personal experience If you believe in progress, have a permanent partner and do not consider abortion a means of protection, there is a huge chance that sooner or later you will get hooked on oral hormonal contraceptives. Health does not deteriorate overnight, unfortunately.

generative action. DO NOT DRINK. Before, everything was fine with me, the only thing was the cycle was broken. It hurt so much that nothing was removed. If I knew that it would be so, I would not take contraceptives. Superficial thrombophlebitis in history can also be considered as a risk factor for thrombosis, especially if it is combined with aggravated heredity. Hi all! I have been taking Chloe for 5 years.

When choosing hormonal preparations, special attention should be paid to the composition of synthetic hormones, since their presence or absence affects the functioning of the girl's body and can have such consequences as: Menstrual cycle failure. Who knew that it was like drugs, and how long it will last now, I don’t know.

When the drug is chosen correctly, the adaptation of the female body takes place during the first 2-3 months, after which the bleeding should enter the normal mode and begin strictly on the 28th day of the cycle. Many friends who are on Milian, who are on Dimiya. If you find one or more of these syndromes, there is no time to hesitate, you should immediately contact your gynecologist. After such a story, you yourself understand that hormonal drugs are a sore subject for me. Most often, the composition of the tablets includes ethinylestradiol (EE). Horror.

It is impossible to completely remove estrogens from the composition, since they play an important role in maintaining a normal menstrual cycle. In addition, there are symptoms of virilization (male secondary sexual characteristics). Third-generation progestins in combined oral contraceptives have increased the incidence of adverse hemolytic changes and the risk of thrombosis, so they should not be given as first choice in hormonal contraceptive beginners. And if he were to be left all alone. I constantly wind myself up, some kind of mania. I took Triziston and Triquilar for almost five years. Climate change. In most cases, such a decision is caused by the desire to have a baby or switch to another type of contraceptive. The gynecologist prescribed chloe to drink for 6 months.

Good day. Action of tablets

I stopped drinking regulon the consequences (video on the topic)


Girls often turn to a gynecologist with the question: “I take anti-pregnancy pills, why don’t I have periods?” The use of contraceptives in the form of birth control pills causes hormonal changes in the body of any girl. Before taking Diana, there were no problems on the part of the psyche, she was always very cheerful. And after that, doctors from different clinics continue to prescribe this dangerous drug to Diana -35. And hot flashes, and pressure, and wanted to hang herself. Therefore, there is no reason to say that the consequences of contraceptive use are infertility, obesity, uncontrolled bleeding and other health problems. On the basis of such stress, I started a strong hormonal failure (I will not describe the symptoms, otherwise you will be scared) and no one can do anything. Help advice. Such reactions are observed briefly in all after childbirth.

As soon as these symptoms occur, consultation with your doctor is necessary - perhaps the drug is not suitable and needs to be replaced. I drank oral contraceptives for three years, and still, as an invalid, I cannot leave the house. Visual impairment. The next day I had a terrible pain in my lower abdomen.

Also, the use of these drugs may have other consequences: Nausea. Unwanted estrogen In the course of a thorough study of hormonal contraceptives and their effects on the body, it was concluded that undesirable effects are associated to a greater extent with the influence of estrogens. For the time being, I still believe that it is necessary to pick up the oormon. A pronounced or very pronounced gestagenic effect is inherent in all progestogens. To be honest, I didn't like it. After hormonal 18 years, I am unsuccessfully treated for infertility.

So, why is there a delay / cessation of menstruation while taking birth control? Main reasons: Due to improper prescription and use of drugs. These pills have taken my life. Pregnantnon-users are pregnant women. But the doctor recommended taking more antidepressants for 6 months.

It is expressed in the suppression of the proliferation of the endometrium, caused by the action of estrogens, and its secretory transformation, which is very important for a normal menstrual cycle. Strong stress. During this time, a woman's natural hormonal background normalizes, and her body will be ready to conceive and bear a child. My joints started to hurt! And so, all year long, someone coughs, I get sick with a temperature of 39 and a terrible pain in the joints, it got to the point that I could not hold a spoon. I also suffered from them for a long time, every now and then I had to change OK. Frequent colds, cystitis, mood swings, fatigue. I live in Krasnodar. Appetite woke up not at all for sweet and fatty, but simply for everything! The fourth week began with olfactory hallucinations.

The study of the properties of estrogens and the conclusion that they are the main source of side effects from the use of hormonal contraceptives led scientists to the idea of ​​​​creating drugs with an optimal reduction in the dose of estrogen in them. It is worth drinking these drugs in compliance with a strict regimen, because missing at least one day of admission can cause the most unpleasant consequences: from menstrual irregularities to unexpected pregnancy. On the third pack appeared girdle pain in the abdomen and lower back. This indicates that the body has failed. The division into generations is due to both a change in the amount of estrogen in the preparations and the introduction of newer progesterone analogues into the composition of the tablets. I don't know how to live on. The correct refusal to take birth control pills In the life of almost every woman there comes a moment when she wants to stop taking birth control pills for one reason or another.

The pressure jumped 170/120, they called an ambulance, they sent me to a madhouse. Therefore, when planning a pregnancy in the first three months after giving up birth control pills, experts recommend not rushing to conceive, but using barrier-type contraceptives (condoms and spirals). Hello, I also drink Belura, almost 2 years, everything is regular, I passed all the tests well).

As soon as I started drinking the battle, the hair on my head began to fall out, and on my chest to grow. I have been drinking Femoden for 7 months, there are no side effects. I began to think that I was somehow fake, frozen. Risk of venous thromboembolism among users of drospirenone-containing oral contraceptives American College of Obstetricians and Gynecologists CONCLUSIONS The risk of venous thromboembolism is increased among users of oral contraceptives (3-9/10,000 women per year) compared with non-pregnant and non-users of these drugs (1-5/10,000 women per year). ). After I went around all the existing doctors, I’m even afraid to remember how much money was spent, I got to a psychiatrist.

When changing coil. Jess was protected for 2 months and put the spiral again. And here, based on the topic, there will only be bad reviews, those who are not lucky. Took OK for a short time. It seemed like the perfect effect. AND NOW IT'S LATE to me 38 and having got rid of one danger, I expose myself to the danger of an early infact. Below are excerpts from several reviews (translation by the author of the article of fragments of foreign articles)

Contraceptive pills: harm or benefit? (video on the topic)


Oral contraceptives and the risk of venous thrombosis New England Journal of Medicine Massachusetts Medical Society, USA

Hormonal contraception is used by more than 100 million women worldwide. From the table it is clear that in non-pregnant women and women not using hormonal contraceptives (non-pregnantnon-users), an average of 44 (with a range of 24 to 73) cases of thromboembolism per 100,000 women are registered per year. This is fine?"

In the first three months of taking hormonal drugs, the body adapts. My condition has been going on for two months now. Decreased female libido. A month ago I got my first wrinkle. They do an ultrasound and make a diagnosis. It happened to me twice at nineteen and twenty-four. The physiological effects of gestagens are combined into three main groups. After the cancellation, she almost lost her life: panic attacks, anxiety, weight loss up to 42 kg at the age of 30. Suddenly, one fine day about a year ago, I felt that I needed to stop taking pills.

2. The nominal background has not been restored. I just pray and dream to return that day... I really want to live. I can’t sleep, because when I change my body position from vertical to horizontal, my heart works with great disturbances. Over the period from twenty-four to twenty-eight years, my body must have changed a lot, and I don’t even know what I really am. And I decided to quit. At first I was strewn with small pimples and I became like a teenage girl.

Dear women, when you start drinking pills and feel side effects, you don’t need to quit right away, wait 3 months, the body gets used to it, or finish the pack to the end, throwing it in the middle will cause more harm to yourself. The first week flew by unnoticed. In large doses, gestagens block both FSH and LH (luteinizing hormone, which is involved in the synthesis of androgens, and together with FSH provides ovulation and progesterone synthesis). Excessive physical and mental stress. The composition of oral contraceptives includes various gestagens. I think I got lucky with him. But you need to do it right, following the instructions and advice of experts, then health problems can be avoided.

It would be better to be killed immediately than such treatment. These drugs have been widely used since their discovery, but later their androgenic effect was noticed, manifested in the coarsening of the voice, the growth of facial hair (virilization). And the attacks returned and every day at the same time pressure surges up to 190H and pulse 130. One strip! So I lived up to the first pill-free menstruation. "Non-ovlon" "Ovidon" and others are not used for contraceptive purposes. Good afternoon!

I also developed depression in the form of panic attacks, sleep disturbances, anxiety, etc. 2.5 months after Yarina was canceled. Yeah, and why didn’t I come across such an article when Jess started drinking? I drank them for three years. No weight gain, no acne. After all, this is also stress with the cessation of the flow of certain hormones. I went to all the specialists with complaints and found nothing. You need to check your head and go to a psychiatrist, and not sin on contraceptives. In the instructions for the use of hormonal contraceptives, in addition to side effects, contraindications are listed. And I know for sure that this is because of the contraceptives, because. at the first break, such a difficult physical condition also began, but then I was a little younger and stronger, apparently, and passed after the resumption of counter-x. As you know, hormonal drugs affect appetite, which can lead to obesity.

For a long time I could not understand the true cause of this condition, p.ch. I have been married for 10 years, I have been working for 6 years, there have always been stresses, there is no way in the cities without them, but so that the body did not fly off like that. And off we go. In general, a new life has been going on for three months, and my personal impressions are also ambiguous:

Gynecologist about the consequences and complications after using hormonal contraception (video on the topic)


- my skin has deteriorated greatly, it has ceased to dry constantly, as it was all the pill years, but it began to periodically become irritated and covered with pimples; - I became harder to endure menstruation; - my character improved a lot and everyone noticed it; a bunch of more important and constructive things than to immediately build everyone; - I always know when I ovulate; - olfactory hallucinations continue, in the last month taste hallucinations have been added to them, it’s even funny. Read to get acquainted, God bless!

Hello. 11 years ago I was prescribed Diana-35. The doctor said that this is an adaptation of the body, it will pass. Glory, hello! I read your comment, I realized that exactly this happened to me, how are you? how did you overcome it? I don’t recognize myself, they put up attacks, and I understand that from Diana 35 exactly the same thing happened. How are you? Slava, do you know how contraceptives work? Can you imagine what happens in the body when they are taken? Do you have friends who take contraceptives for a long time and remain healthy until old age? I am almost sure that you have no answers, unfortunately, and then you are right no too talk about that. Contraceptives without estrogen

There are gestagen-containing contraceptives ("mini-drank"). From my personal experience, after 2 packs of Yarina, the veins on the legs became much larger, spider veins appeared. I was diagnosed with diffuse fibrocystic bridge disease at the age of 15. By the way, a hormone analysis before using Ok is not mandatory, because the level of hormones changes even when you are worried or happy. And I'm tired of being sick. If you come to the doctor complaining that your lower abdomen hurts while taking birth control, most likely he will prescribe other drugs. They say that I screwed up myself, that I'm crazy. This means that you need to drink stronger hormonal pills.

The attitude of the doctors was similar. I thought it was a very good product. Very serious consequences of the reception, I had to quit my job and live in this hell for almost a year, Thank God the psychotherapist doctor saved me with the appointment of the antidepressant venlaxor.

Saw (Yarina, Regulon, Marvelon, Belara, Diana-35). Other side effects, such as: decreased mood, mood swings, increased appetite, nausea, stool disorders, satiety, swelling and soreness of the mammary glands, and some others - although they are not severe, however, affect the quality of life of a woman. Only three drugs have a clear antiandrogenic effect. There was a severe migraine, dizziness, nausea, difficulty, frequent, painful urination, burning and shooting pains in the perineum, spasms in the stomach and intestines, severe constipation, diarrhea, severe pain in the heart, tachycardia, fever, constant pain in the lower abdomen, pain in the legs , tearfulness, pain in the lower back and on both sides, pain and difficulty urinating after intercourse. I read your review, you write about taking a product that helps to normalize hormonal levels.

My veins began to ache and bulge. It all started with panic attacks, numbness of the limbs, various pains in the body ... Nobody believed me. Such impression now you will be disconnected and that then it will be unknown. Thromboembolism is the blockage of a blood vessel by a thrombus. It was a completely irrational feeling. The pressure is low all my life - it started to jump, not much yet, but this is enough for me to start headaches. But I know that I can't live like this.

You just need to choose for yourself. Anyone who has experienced this will understand. that living like this is simply not living. So it turned out to be the result of a trip to the doctor. OK, it's like a lottery, really. But taking ok and after even with the time of pregnancy and childbirth gave this result. For me, for example, other methods are not so reliable, and the consequences, you know. With hormonal pills, I am relatively calm about surprises. The first time for 3 months and nothing, probably lucky, but the 2nd time for 2 months in total, now for the 3rd month I have not been drinking anything, as doctors say hormonal withdrawal syndrome. If, even after changing contraceptives, the pain does not stop, but rather becomes sharp, cutting, the body temperature rises, you should stop using these drugs. Think when you publicly express your opinion.

Consequences of hormonal contraception. (video on the topic)


Risk factors for thrombosis (the formation of blood clots inside the vessels - blood clots - interfering with free, laminar blood flow): age over 35 years; high levels of estrogen in the blood (which occurs when taking oral contraceptives); increased blood clotting, which is observed with a deficiency of antithrombin III, proteins C and S, dysfibrinogenemia, Marchiafava-Michelli disease; injuries and extensive operations in the past; venous congestion with a sedentary lifestyle; varicose veins of the legs; damage to the valvular apparatus of the heart; atrial fibrillation, angina pectoris; diseases of the cerebral vessels (including transient ischemic attack) or coronary vessels; arterial hypertension of moderate or severe degree; connective tissue diseases (collagenoses), and primarily systemic lupus erythematosus; hereditary predisposition to thrombosis (thrombosis, myocardial infarction, cerebrovascular accident in the closest blood relatives). Avoidance of oral contraceptives in these women may lead to a reduction in the incidence of arterial thrombosis, as reported by recent studies in industrialized countries. After scolding the parents, they nevertheless took an ECG and injected a sedative, and everyone said it was not for us. They prescribed treatment, she was treated in neurology, antipsychotics, antidepressants, I still drink periodically. Holding my breath, I began to wait for PMS. Superficial varicose veins are not a consequence of pre-existing venous thrombosis or a risk factor for deep venous thrombosis. These states include the following:

Arterial hypertension. One side. temperature in the evening 37. Two years later, she and her husband decided to increase the family, they already have one child.

Thromboembolism cannot occur out of the blue, it requires special “conditions” of risk factors or existing vascular diseases. The moral of the story is this: do not take hormonal drugs. Others may conceive within a few months of stopping contraceptives, but no sooner than three months. And this, in turn, affects the hormonal background of the body and directly affects the female secretions. The doctor will examine the condition of the mammary glands and genital organs, if necessary, the specialist will also offer to do additional tests. Progesterone-only preparations are safe in relation to the risk of venous thromboembolism. Because contraceptives lead to a deficiency in the body of a number of vitamins. This is normal, but only if it does not happen often. And all these reactions are the body's reaction to stress after cancellation. But the worst thing was that after taking the drug for six months there was no menstruation.

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Thanks

general information

Hormones are active substances that are involved in all physiological processes. They are produced by the endocrine glands and coordinate various processes: growth, reproduction, metabolism, and so on.

Hormone therapy in children

This type of treatment requires special qualifications from doctors, since the use of even the “lightest” hormonal agent necessarily reduces the activity of the gland that secretes it. At the same time, it must be understood that the final endocrine glands develop only by the age of twenty-five. Therefore, the inept use of hormones can disrupt the natural process of the formation of the endocrine system.

Children are prescribed hormonal drugs only in special cases and those that are quickly destroyed in the body ( prednisolone, hydrocortisone). It is better to give a medicine containing hormones to the baby at the time ( or before) breakfast.
Insulin preparations are prescribed very carefully for babies. The presence of glucose in the urine does not necessarily indicate diabetes. There are many diseases that are similar in their manifestations to diabetes, but not all of them are associated with a lack of insulin. Usually, in the treatment of such diseases in hospitals, hormonal agents are not used.

After infectious diseases and in case of disruption of the endocrine glands, in some cases, babies are prescribed anabolic steroids, but they categorically cannot be used for ailments of an infectious-allergic nature ( e.g. collagenoses, glomerulonephritis).
Any hormonal drugs can be given to babies only after consulting an endocrinologist and in strict accordance with the prescribed dosage.
During the course of treatment, you need to carefully monitor the condition of the baby, his body weight, and the work of the digestive system.
If prednisolone is prescribed, it is necessary to periodically check the amount of calcium and sugar in the blood, make sure that the child does not have an increase in body hair, pressure does not rise, and there are no signs of a decrease in adrenal function.

Replacement therapy for menopause

During menopause, a woman's body produces not only less female sex hormone - estrogen, but also its weaker form - estrone. Thanks to the introduction of replacement therapy, the level of the female sex hormone in the body normalizes, which has a beneficial effect on the state of the body.

Pros:

  • The work of the brain is activated,
  • Sleep is normalized
  • Normalizes blood pressure
  • Normalizes heart rate
  • Collagen fibers are strengthened in blood vessels, cartilage, skin,
  • Prevention of atherosclerosis increases the amount of high-density lipoprotein - good cholesterol),
  • Reduces the likelihood of a heart attack, heart attacks, reduces the likelihood of death from coronary diseases by half,
  • Reduces the risk of stroke by 50%
  • 50% less chance of fractures due to osteoporosis,
  • Eliminates symptoms of menopause such as vaginal dryness, itching of the vulva, atrophy of the vaginal mucosa, impaired urination,
  • The work of the thyroid gland is regulated,
  • Does not increase body weight under the influence of testosterone.
Contraindications:
  • Severe forms of diabetes,
  • Violation of the liver,
  • Vaginal bleeding of unknown nature.
A large selection of drugs for substitution therapy, as well as modern diagnostic methods, make it possible to choose an individual course of treatment for each of the fair sex. There are very few hormones in such drugs, which reduces the likelihood of side effects.

Before prescribing medications, the doctor will send you for an examination that reveals common diseases, the course of which can be aggravated when taking hormones. You will need to go to a gynecologist's appointment, do an ultrasound examination of the pelvic organs, take an analysis for oncocytology, examine the condition of the chest, check blood pressure, body weight, donate blood for cholesterol and a general analysis, for sugar, as well as a urine test.
During the course of replacement therapy, it is necessary to undergo annual examinations by a doctor and ultrasound control.

Replacement therapy in gynecology

Indications:
  • Menopause,
  • Previous ovarian failure
  • Hypogonadotropic amenorrhea,
  • gonadal dysgenesis,
  • Normalization of the state of the endometrium after surgery or in the chronic form of endometritis,
  • Medical menopause.
When treating women with infertility, hormone therapy is prescribed during ovulation stimulation, during in vitro fertilization, when using donor oocytes.

Steroid hormones are used in treatment because they affect many internal organs. Their lack negatively affects the state of fatty tissue, liver, dermis, bones, digestive system, reproductive organs, blood vessels, brain.

Hormonal preparations of the latest generations, practically, one to one, imitate natural ones, their concentration in the blood. The treatment uses small doses of sex hormones that do not interfere with ovulation and do not have a contraceptive effect.
The use of hormones in the treatment of infertility boils down to the fact that with a natural lack of hormones in the patient's body, with the help of their artificial analogues, conditions are created that are as close to normal as possible. Thanks to this, fertilization and gestation of the fetus is carried out. When prescribing dosages of drugs, one of the most important indicators is the condition of the endometrium.

With amenorrhea and early menopause, hormonal drugs are taken in cycles. Treatment continues until the age of normal menopause. If a woman wants children, hormone intake is not interrupted, as it helps to normalize the condition of the endometrium.

Tumors are divided into three groups:

  • hormonal,
  • hormone-dependent,
  • Hormone dependent.
hormone-dependent neoplasms that appear as a result of disruption of the endocrine system are called. One of these tumors is breast cancer, which develops when the function of the ovaries or thyroid gland is impaired.
The appearance of such a tumor does not in all cases indicate the advisability of hormone treatment.

Hormonally active are tumors that secrete hormones. Such neoplasms have a double destructive effect on the body. These include cancer of the adrenal or pituitary gland, pancreas, thyroid gland. They can also appear on other organs that do not produce hormones in a healthy state ( e.g. intestines or lungs).

Hormone dependent - These are neoplasms, the existence of which is impossible without the presence of certain hormones. A change in the hormonal background of the body, the cessation of the production of the hormone necessary for the tumor, leads to inhibition of tumor development. Some tumors of the breast, testicles, ovaries, prostate, kidneys, thyroid, and uterus can be included in this category. That's for the treatment of such tumors and hormone therapy is needed.

Hormone therapy is usually used for metastasis ( occurrence of secondary tumors). The effect depends on how sensitive the tumor is to hormones. Sometimes this method is prescribed in the early stages in combination with other methods.
The most significant results have been achieved in the treatment of breast and prostate cancer with hormones.

Therapy for breast cancer

The female sex hormone estrogen in many cases is an activator of the appearance of malignant tumors of the breast. Estrogens interact with proteins in the upper layers of the neoplasm and accelerate the division of malignant cells.

The use of hormones in breast cancer leads to:

  • Decrease in the amount of estrogen produced by the ovaries,
  • Inhibition of the activity of breast receptors for progesterone and estrogen,
  • Decreased production of estrogen by the adrenal glands
  • Inhibition of the activity of the hormone itself by increasing the level of male sex hormones.
Hormonal treatment is often combined with chemotherapy. It is easier to tolerate and has less effect on the functioning of the body as a whole.
If the tumor is sensitive to this type of therapy, then it can eliminate itself completely along with metastases. Often, it is thanks to this type of treatment that patients live longer by several decades.

Therapy after removal of the ovaries

After the removal of the ovaries, young patients begin to experience the sensations that are observed in menopausal women. Already after 15 - 20 days, symptoms of malaise appear, which begin to seriously annoy 8 - 12 weeks after the operation. This is due to the fact that estrogen residues are gradually removed from the body and an early menopause develops.
The woman begins to experience fever, increased work of the sweat glands, tachycardia, she has unstable pressure and mood, often has a headache, poor sleep and no interest in the opposite sex.
After some time, these unpleasant signs will disappear, but other, more dangerous ones will come in their place: dysfunction of blood vessels, urinary organs, and external genital organs.

Some hormones are produced by the adrenal glands. However, their work is not enough. Therefore, women are prescribed hormone replacement therapy. Hormonal drugs can be drunk until the end of life, which will prevent the development of early menopause and allow a woman to feel good for a long time.
In the event that the removal of the ovaries was about a malignant tumor, hormonal treatment is usually prohibited. Then homeopathic remedies are prescribed instead.

For psoriatic arthritis

In severe cases of joint damage with psoriasis, the following drugs containing glucocorticoids are prescribed:
  • Kenalog ,
  • Flosteron ,
  • Diprospan ,
  • Hydrocortisone ,
  • Metipred .
Positive effect of treatment:
The patient's condition quickly improves: pain in the affected joints is relieved, their mobility increases, fever and lethargy disappear.

Negative effect of treatment:

  • Immunity is suppressed, which provokes abscesses on the body,
  • Drugs are addictive
  • Side effects: hypertension, obesity, diabetes mellitus, edema,
  • It is forbidden to use drugs constantly and for a long time,
  • May contribute to the development of stomach ulcers,
  • The drug should not be canceled immediately, as the patient's condition will worsen sharply.

Against acne

Hormone treatments can sometimes help those who suffer from acne on the face and body. The use of hormonal drugs reduces the production of sebum by the skin glands, so the skin is actually cleared.
But many notice that after the end of taking the drug, acne appears again. In order for the effect to last, hormones should be combined with skin treatment with special antibacterial agents. Means should be selected on the basis of natural ingredients, not containing antibiotics and chemicals.

Side effects observed when taking hormonal drugs to cleanse the skin of acne:

  • Headache,
  • Increase in body weight,
  • Depressed mood
  • swelling,
  • Individual intolerance to the drug.
You should not experiment with drugs on your own. It is better to get the advice of doctors: a dermatologist and an endocrinologist.

Transsexuals and hormone therapy

Estrogen preparations are used to suppress the production of testosterone and give the body female features. In addition, progestogens are used, under the influence of which the mammary glands increase.
Antiandrogens suppress the production of male sex hormones. The use of these hormones makes it possible to reduce the dosage of estrogen drugs and reduce the sensitivity of internal organs to the action of testosterone.
In order to suppress the production of estrogen, testosterone preparations are taken.

Hormone therapy for sex change is divided into two phases:
1. First months of treatment six months) hormonal drugs are taken in large dosages, which allows you to achieve the desired result in a shorter time. As soon as the desired result is obtained or if the maximum dosage of hormonal drugs is taken, the doses should be slowly reduced. Hormonal preparations should be completely canceled 20 to 30 days before surgery to reduce the likelihood of developing blood clots. This phase of treatment suppresses the work of the gonads and helps the appearance of signs of the desired sex. Also, the treatment helps to prevent a severe complication of the operation - post-castration syndrome, characterized by lethargy, weakness and craving for sleep.

2. The second phase begins after the operation. After removal of the testicles, antiandrogens are stopped. After the removal of the uterus and ovaries, the dosage of drugs to suppress the production of female sex hormones is reduced. However, in order for the hormonal background to match the chosen sex, therapy is carried out throughout life.

Taking hormonal therapy allows you to achieve a change in the appearance of a transsexual according to the desired sexual type.
Most often, hormones are taken orally in the form of tablets. But there are drugs in the form of patches, gels, liquids for injection.
Since the use of hormone therapy increases the density of the blood, thrombosis, stroke, and heart attack may develop as a side effect. The likelihood of developing heart and vascular diseases, breast cancer, osteoporosis and Alzheimer's disease increases.
To minimize the likelihood of developing side effects, you need to give up nicotine, balance the menu, lead a healthy lifestyle and from time to time carry out general diagnostics. In no case should you cancel or prescribe hormonal drugs yourself.

It should be understood that the effect of taking hormonal drugs comes gradually and rather slowly. Only 24 months after the start of treatment, you can achieve the maximum result.
The effect of the drugs may be stronger or less depending on age, genetic characteristics. The strongest effect is observed in people aged 18 to 21 years. But if the patient is over 30 years old, magic will not happen.

But there are indicators that even hormones cannot affect.
It:

  • Facial hair. The hair will not be as coarse, but it will not disappear completely,
  • The chest may increase quite a bit,
  • Shoulder width, height and size of legs and arms will not change,
  • The voice will not change either.

The consequences of therapy in men

Hormone therapy with female sex hormones causes:
  • Decreased attraction to the opposite sex
  • Flushing to cheeks and upper body
  • Osteoporosis and bone fractures
  • Enlargement and tension of the mammary glands,
  • Decrease in the level of red blood cells,
  • Decreased memory function
  • Decrease in muscle mass, increase in body weight due to fat,
  • Lethargy and fatigue
  • An increase in the amount of cholesterol in the blood,
  • Depressed mood.
In men taking such treatment, the risk of diabetes, hypertension, and heart disease increases.
Before use, you should consult with a specialist.
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