What products contain methylsulfonylmethane? Possible side effects of methylsulfonylmethane

Compound

Methylsulfonylmethane, microcrystalline cellulose, amorphous silicon dioxide, croscarmellose, magnesium stearate, stearic acid, hydroxypropyl methylcellulose, hydroxypropylcellulose, polyethylene glycol, titanium dioxide

Description

MSM - to reduce inflammation in joints, swelling, reduce pain, quickly restore joints and muscles, including after training

Methylsulfonylmethane, an organic sulfur-containing compound, is a key metabolite of dimethyl sulfoxide (DMSO) and contains 34% organic sulfur. MSM is part of many endogenous proteins (including connective tissue proteins - collagen, elastin, keratin), hormones and other metabolically active compounds. MSM has anti-inflammatory and analgesic effects.

Numerous foreign studies have shown that MSM promotes faster recovery of joints and muscles after physical activity, and has anti-inflammatory, antioxidant, and anti-allergenic properties. MSM is involved in the formation of connective tissue, the biosynthesis of collagen, which promotes skin elasticity and muscle strengthening, promotes wound healing, and has a positive effect on skin condition and hair growth.

MSM has been studied for its benefits in treating arthritis and other complications of joint inflammation. The results of studies conducted by American scientists showed that with the targeted intake of MSM as a dietary supplement in patients with arthritis, the inflammatory process and the rate of cartilage destruction significantly decreased.

Researchers say that MSM, when taken in the right dosage, can help:

Reduce inflammation in joints;

Reduce swelling and stiffness of joints;

Improve blood circulation and cell viability;

Reduce pain associated with inflammatory processes;

Destroy calcium deposits.

1000 mg methylsulfonylmethane (MSM) helps:

Reducing inflammatory processes in joints and reducing pain;

Reducing swelling of the joints,

Rapid recovery of joints and muscles after training.

2 tablets contain - Methylsulfonylmethane - 1000 mg (1 gram)

The tablets are round, biconvex, white coated, white at the break

Selling Features

Without a license

Special conditions

Indications

as a biologically active food supplement containing methylsulfonylmethane and helping to reduce inflammation in the joints and reduce pain, reduce swelling of the joints, rapid recovery of joints and muscles after training, and improve the condition of the skin, hair and nails. Supports joint mobility and flexibility.

Contraindications

Individual intolerance to product components, pregnancy, breastfeeding.

Should you take MSM? This compound is known to be reliable in reducing muscle pain and speeding up recovery. In this article, we will cover all the potential benefits of this dietary supplement.

Methylsulfonylmethane, or MSM (MSM)– a common food additive. MSM has gained a lot of popularity in the bodybuilding industry over the past few years, with many large-scale studies demonstrating that it provides a host of health and performance benefits. Specifically, MSM has been shown to reduce pain and inflammation associated with exercise, reduce oxidative stress, and speed up recovery.

In this article, we'll review the available evidence on the uses and benefits of MSM to help you decide whether it's worth adding to your sports nutrition stack.

What is MSM?

Methylsulfonylmethane (MSM) is a naturally occurring chemical compound that is formed from sulfur in the earth's crust and penetrates into aquatic environments such as oceans, rivers and lakes, where it then enters the soil. MSM contains organic sulfur, which is considered an essential dietary mineral. Sulfur is the third most abundant element in the human body relative to body weight.

Due to its small molecular size and high ability to penetrate cell walls, MSM comes from the soil into plants, and then into the body of animals that feed on them.

This is why MSM is found in most natural plant foods - fruits, vegetables and grains. MSM can also be taken in dietary supplement form, making it easier to get a higher dose of MSM than is possible by consuming natural sources alone.

How MSM works

As a sports supplement, MSM is used to reduce pain and inflammation after exercise and to improve overall physical performance. MSM is often included as an additional ingredient in supplements. As a result of the research, it was concluded that when combined, these products provide a greater effect than when consumed separately.

MSM also works as an antioxidant, which reduces the harmful effects of free radicals in the body. This very small molecule moves easily within and between cells, allowing it to be distributed throughout the body and have positive effects at the tissue and cellular level.

Proven benefits of MSM

The positive effects of MSM supplementation on pain reduction and functional improvement of joints and ligaments are supported by both clinical and randomized controlled studies.

One study tested the consumption of 1.5 and 3 gram daily doses of MSM for 30 days. It was found that when taking MSM, subjects recovered faster from strength training and noted a decrease in muscle fatigue and soreness.

A recent meta-analysis of MSM studies conducted in 2017 refutes earlier suggestions that the benefits of MSM are not clinically significant. The study authors found that the health and performance benefits of MSM are well documented and substantiated in a variety of sources.

Recent research has shifted the focus to examining the benefits of MSM for people with metabolic syndrome.

Does MSM have side effects?

Consumption of MSM is considered completely safe. The Food and Drug Administration (USA) recognized MSM as a safe product back in 2007.

The longest MSM study to date, a 26-week supplement study, found no side effects even at 6 grams per day. However, pregnant and breastfeeding women are not recommended to take MSM due to insufficient research on the effects of MSM on this category of people.

Are there any natural forms of MSM?

In fact, it is not uncommon for you to consume MSM as part of your regular nutrition plan. MSM is found in large quantities in cow's milk, coffee and tea. Natural MSM is also found in tomatoes, corn, apples, raspberries and even beer!

However, the concentration of MSM in natural food sources is relatively low. That's why, as research points to the powerful pain-relieving and anti-inflammatory effects of MSM, a synthetically produced product has become widespread.

It has the same properties as natural, allowing you to supplement your diet with a higher dose of MSM without having to consume unrealistic amounts of food.

In most studies, MSM was taken orally, with dosages ranging from 500 mg to 3 g twice daily. The Recommended Daily Allowance (RDA) is determined in part by the intended outcome of consuming the supplement. For example, as part of a study on the effectiveness of antioxidant properties and therapy for osteoarthritis, the dose of MSM varied from 1.5 to 3 g per day. To improve recovery from soft tissue injuries, it is enough to take 50 mg of MSM. The highest reported dose of MSM intake in the scientific literature is 6 grams per day.

Does MSM interact with other medications?

When interacting with certain medications, MSM can cause drowsiness and have effects similar to antihistamines.

MSM occurs naturally in the human body through food and is safe to take in dietary supplement form. MSM provides a wide range of benefits, including improved joint function, increased recovery from exercise, reduced pain and inflammation, and reduced oxidative stress.

The cost of MSM supplementation is relatively low and is well worth it for people who are looking to reduce inflammation and joint pain and return to normal physical activity. For athletes and bodybuilders, MSM can be a valuable addition to a sports nutrition stack to improve recovery and reduce joint inflammation.

Active ingredients

• Not indicated. See instructions

Pharmacological action

• Not indicated. See instructions

Description of pharmacological action

Promotes regeneration (restoration) of damaged cartilage tissue.
It has an anti-inflammatory effect, relieves pain and tension in the joints, increases their mobility, and reduces swelling.
Participates in the formation and improves the trophism of connective tissue of articular surfaces, tendons, ligaments, synovial fluid, skin, bone tissue, nails, heart valves, blood vessels and mucous membranes of the digestive, respiratory and urinary tracts.
It has a beneficial effect on cartilage metabolism - enhancing anabolic and weakening catabolic processes.
Stimulates collagen synthesis.
Inhibits the activity of enzymes that destroy connective tissue, incl. cartilage.
Improves microcirculation of the vascular bed of periarticular tissues.
Stimulates the synthesis of hyaluronic acid, which provides lubrication necessary for the functioning of joints.
Participates in the processes of bone mineralization, regulating calcium balance and promoting ossification processes.
Has an antithrombotic heparin-like effect.
Chondroitin sulfate is also necessary for any pathological processes of connective tissue, not only cartilage, but also tendons, ligaments and, of course, skin. Therefore, not only sports doctors should have chondroitin sulfate in their arsenal, but also competent dermatologists and cosmetologists. Unfortunately, the latter very rarely turn to cosmetic products for oral administration. Chondroitin sulfate, like vitamins A, B, C, E, can be called enteral cosmetic preparations.
Promotes healing of fractures, wounds, erosions, ulcers.
Reduces the concentration of cholesterol in the blood, prevents the accumulation of atherosclerotic plaques on the walls of blood vessels, and improves blood circulation.
Methylsulfonylmethane (organic sulfur, MSM) provides the molecular structure of protein, is part of many amino acids, and is involved in the synthesis of antioxidants, in particular glutathione. Sulfur is essential for joint tissues, where it is responsible for the stability of cartilage tissue, capsule and ligaments. MSM has a positive effect on joint pain, helps restore joint mobility, and also improves the permeability of cell walls, allowing fluid and substances dissolved in it to more easily penetrate cell membranes. This facilitates the removal of substances such as lactic acid and taxins from the cells, and the entry of nutrients and microelements into the cells. MSM prevents an increase in intracellular pressure, which relieves pain.

Compound

Glucosamine sulfate (from 1500 mg potassium glucosamine sulfate complex) 1100 mg
MSM (methylsulfonylmethane) 300 mg
Chondroitin sulfate sodium (from bovine cartilage) 1200 mg
Sodium 110 mg
Potassium (potassium chloride) 245 mg
Other Ingredients: Gelatin (capsule) and magnesium stearate (vegetable source). Contains shellfish (crab, shrimp, lobster, crayfish).

Indications for use

Inflammatory and metabolic diseases and injuries of the osteoarticular system: osteoporosis, osteochondrosis, fractures, ankylosing spondylitis, tendovaginitis, bursitis, arthritis, arthrosis, gout, rheumatoid polyarthritis.
Recovery period after injuries, bone fractures, and “jumper’s knee” in athletes.
Wound healing effect (postoperative conditions, trophic ulcers).
Increased brittleness of nails, hair loss.
Cardiovascular diseases (varicose veins, heart defects, atherosclerosis).
In cosmetology to restore skin texture, improve tone, smooth out and reduce the number of wrinkles, skin rejuvenation, treatment of hyperpigmentation.

Release form

tablets 1650 mg;

Directions for use and doses

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25 °C.

Best before date

The description of the vitamin Glucosamine + Chondroitin + MSM is intended for informational purposes only. Before starting to use any drug, it is recommended to consult a doctor and read the instructions for use. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the project does not replace consultation with a specialist and cannot be a guarantee of the positive effect of the drug you use. The opinions of EUROLAB portal users may not coincide with the opinions of the site Administration.

Are you interested in vitamin Glucosamine+Chondroitin+MSM? Do you want to know more detailed information or do you need a doctor's examination? Or do you need an inspection? You can make an appointment with a doctor– clinic Eurolab always at your service! The best doctors will examine you, advise you, provide the necessary assistance and make a diagnosis. you also can call a doctor at home. Clinic Eurolab open for you around the clock.

Attention! The information presented in the vitamins and dietary supplements section is intended for informational purposes and should not be a basis for self-medication. Some of the drugs have a number of contraindications. Patients need to consult a specialist!

If you are interested in any other vitamins, vitamin-mineral complexes or dietary supplements, their descriptions and instructions for use, their analogues, information about the composition and form of release, indications for use and side effects, methods of use, dosages and contraindications, notes about the prescription of the drug for children, newborns and pregnant women, price and consumer reviews, or you have any other questions and suggestions - write to us, we will definitely try to help you.

Methylsulfonylmethane is a drug intended primarily for maintaining athletic fitness and beauty. Moreover, its leading effect is anti-inflammatory. You will learn why this substance has such an unusual combination of properties from this post describing the additive MSM-1000 (MSM-1000). Surely you will want to take it too!

MSM-1000 (MSM-1000): composition and release form

In each capsule:

• Methylsulfonylmethane - 1000 mg.

Release form: jar containing 120 capsules.

MSM-1000 (MSM-1000): properties

MSM is organically bound sulfur of natural origin. Sulfur is very important for the formation of joint components as well as skin fibers. In addition, sulfur-containing enzymes produced by the body have a fairly noticeable anti-inflammatory effect and affect the full functioning of the nervous system.

In more detail, MSM-1000:

• Accelerates the recovery of joints and ligaments after sports injuries: relieves inflammation, improves metabolic processes, accelerates healing. Some studies also suggest that MSM has an analgesic effect, that is, a pain-relieving effect.
• Improves skin condition as it promotes the formation of collagen and elastin.
• Helps increase attention, improve memory, accelerate thought processes, and normalize sleep.
• Provides faster growth of hair and nails, and with long-term use improves their quality.
• It has an effect that can conventionally be called anabolic. Sulfur is a necessary component of protein molecules, and protein is the basis of muscles. Taking dietary supplements improves the performance of sports training.

MSM-1000 (MSM-1000): indications and contraindications

Indications for taking MSM-1000 include:

According to experts from different countries, MSM is the best existing source of sulfur for the body, which is well absorbed by the body. For this reason, dietary supplements can be confidently considered an effective and safe remedy.

A contraindication to taking the supplement is intolerance to the active ingredient in the capsules. Rarely observed. It is worth noting that never in the entire practice of using methylsulfonylmethane has a drug overdose been detected in a single person.

MSM-1000 (MSM-1000): instructions for use

If the drug is taken for the treatment of joint disorders, it can be combined with dietary supplements such as glucosamine, chondroitin.

MSM-1000 is taken 1-2 times a day. Drink 2 capsules of the product at a time. It is recommended to continue the course for at least 1 month.

It is not a medicine (dietary supplement).

MSM-1000 (MSM-1000): price and sale

In order to buy MSM-1000, you just need to dial the phone number of our store or send a request through the website. Our employees will discuss with you all the necessary nuances and promptly send the parcel in the most convenient way for you. The price for MSM-1000 is indicated above. If you want, after ordering you can pick up your purchase yourself from our office in Moscow.

For regions there is a toll-free number 8 800 550-52-96.

The drug is manufactured by NOW Foods, Bloomingdale, IL 60108 U.S.A.

Delivery in Moscow and the Moscow region:

P when ordering from 9500 rub. FOR FREE!

When ordering from 6500 rub. delivery in Moscow and beyond the Moscow Ring Road (up to 10 km) - 150 rub.

When ordering less than 6500 rub. delivery in Moscow - 250 rub.

When ordering outside the Moscow Ring Road for the amount less than 6500 rub.- 450 rubles + transportation costs.

By courier in the Moscow region - price is negotiable.

Delivery in Moscow is carried out on the day the goods are ordered.

Delivery within Moscow region is carried out within 1-2 days.

Attention: You have the right to refuse the goods at any time before the courier leaves. If the courier has arrived at the delivery point, you can also refuse the goods, BUT paying for the courier's departure according to delivery rates.

Sale and delivery of medicines is not carried out.

Delivery in Moscow is carried out only for order amounts over 500 rubles.

Delivery across Russia:

1. Express mail 1-3 days (to your door).

2. By Russian Post within 7-14 days.

Payment is made by cash on delivery or by transfer to a bank account (download details).

As a rule, the cost of express delivery is not much higher than delivery of goods by Russian Post, but you have the opportunity to receive the goods in a guaranteed short time with home delivery.

When ordering goods by cash on delivery you pay:

1. The price of the product you ordered on the website.

2. Delivery price depending on weight and delivery address.

3. Mail commission for sending the cash on delivery amount back to the seller (by prepaying to a bank account, you save 3-4% of the total purchase amount).

Important: For order amounts up to 1,500 rubles, parcels within the Russian Federation are sent only with prepayment.

Important:All orthopedic products are shipped within Russia only upon prepayment.

You can check the final payment amount for your order with our managers.

You can track the delivery of the ordered goods by using a special service on the website www.postal-rossii.rf in the "postal tracking" section where you will need to enter your mailing ID, which is sent to you by managers during the process of sending the goods. Also, for your convenience and to minimize the time it takes to receive your parcel, delivery service managers track the movement of the parcel, and on the day the parcel arrives at your post office, they inform you via SMS message. Having received an SMS message, you can present your ID number and pick up your order from the post office without waiting for a postal notification of the parcel's arrival.

Artra MSM Forte: instructions for use and reviews

Artra MSM Forte is a combination drug with an anti-inflammatory effect that stimulates the process of regeneration of cartilage tissue.

Release form and composition

The dosage form of Artra MSM forte is film-coated tablets: from dark orange to light yellow-orange in color, biconvex oval shape; the presence of a specific odor is acceptable (in a cardboard pack there is 1 polyethylene bottle of 30, 60 or 100 pcs., or 2–4, 6, 9 or 10 blisters of 10 or 15 pcs. each).

Active ingredients in 1 tablet:

• sodium hyaluronate (in terms of hyaluronic acid) – 10 mg;
• glucosamine hydrochloride – 500 mg;
• sodium chondroitin sulfate – 400 mg;
• MSM (methylsulfonylmethane) – 300 mg.

Auxiliary components:

• core: colloidal silicon dioxide – 4 mg; microcrystalline cellulose – 199.4 mg; croscarmellose sodium – 50 mg; calcium hydrogen phosphate dihydrate – 119.6 mg; stearic acid – 48 mg; Magnesium stearate – 10 mg;
• shell: Opadry II orange (sunset yellow aluminum varnish dye – 0.92 mg; medium chain triglycerides – 0.6 mg; hypromellose – 17.56 mg; maltodextrin – 4.68 mg; polydextrose – 7.92 mg; dye titanium dioxide – 0.44 mg; talc – 7.88 mg) – 40 mg.

Pharmacological properties

Pharmacodynamics

Artra MSM forte has an analgesic and anti-inflammatory effect. The components of the drug have the ability to inhibit the progression of osteoarthritis. Other effects include suppressing the destruction and stimulating the regeneration of cartilage tissue, improving blood flow in the subchondral bone, and reducing the need for non-steroidal anti-inflammatory drugs.

The main properties of the components of Artra MSM Forte:

• sodium chondroitin sulfate - takes part in the synthesis of connective tissue and is an additional substrate in the formation of a healthy cartilage matrix. Stimulates the synthesis of proteoglycans and collagen type II, the formation of hyaluronan, and also maintains the viscosity of synovial fluid, protects hyaluronan from the damaging effects of free radicals and enzymatic breakdown (by suppressing the activity of hyaluronidase);
• glucosamine hydrochloride – takes part in the synthesis of connective tissue; with the introduction of exogenous glucosamine, the production of cartilage matrix is ​​enhanced and nonspecific protection against chemical damage to cartilage is provided;
• MSM is a sulfur-containing organic compound (natural sulfur content – ​​34%). Has analgesic and anti-inflammatory effects. It is one of the key metabolites of dimethyl sulfoxide. Part of many endogenous proteins (including connective tissue proteins - elastin, collagen, keratin), hormones and other metabolically active compounds;
• hyaluronic acid is a polysaccharide of the acid glycosaminoglycan group; it is one of the important components of synovial fluid and determines its viscoelastic properties. The substance forms a covering layer on the entire internal surface, which helps protect articular cartilage and synovial membrane from mechanical damage, as well as from inflammatory factors and free radicals.

Pharmacokinetics

When taken orally, the bioavailability of glucosamine is 25% (first pass effect through the liver).

The plasma concentration of chondroitin sulfate with a single oral dose of 800 mg (or 2 times a day 400 mg) increases sharply for 24 hours. Absolute bioavailability is 12%. Approximately 10 and 20% of the dose taken, respectively, is absorbed as high-molecular and low-molecular derivatives.

In experimental models, when administered orally, a certain bioavailability of hyaluronic acid was noted.

Chondroitin sulfate is distributed in tissues. Its highest concentrations are found in articular cartilage, kidneys and liver. Approximately 30% of the dose taken persists for a long time in muscle and bone tissue.

Glucosamine is excreted mainly unchanged by the kidneys; partly through the intestines.

Chondroitin sulfate is metabolized through desulfuration. Excreted in urine. T1/2 (half-life) – more than 5 hours.

Indications for use

• osteocondritis of the spine;
• osteoarthritis of peripheral joints.

Contraindications

Absolute:

• pregnancy and lactation;
• age up to 15 years;
• individual intolerance to the components of the drug.

Relative (Artra MSM forte is prescribed under medical supervision):

• diabetes;
• bleeding disorders;
• intolerance to seafood (shellfish, shrimp);
• bronchial asthma.

Instructions for use of Arthra MSM Forte: method and dosage

Artra MSM Forte tablets are taken orally.

The duration of the course is at least 3 months.

Side effects

Possible adverse reactions: disorders of the digestive system (in the form of epigastric pain, flatulence, diarrhea, constipation, nausea, vomiting), allergic reactions.

Overdose

There are no reports of cases of overdose.

Probable main symptoms: nausea, vomiting, diarrhea, hemorrhagic rashes.

Therapy: symptomatic (gastric lavage).

special instructions

If you have chronic diseases, a medical consultation is required before starting the course.

Use during pregnancy and lactation

According to the instructions, Artra MSM forte is not prescribed during pregnancy/lactation.

Use in childhood

Artra MSM forte is not prescribed to patients under 15 years of age (the safety profile has not been studied).

Drug interactions

Artra MSM Forte is compatible with non-steroidal anti-inflammatory drugs and glucocorticosteroids.

Possible interactions:

• semisynthetic penicillins: decreased effect;
• tetracyclines: increasing their absorption;
• indirect anticoagulants, antiplatelet agents, fibrinolytics: enhancing their action.

Analogs

Analogues of Artra MSM Forte are Theraflex M, Piaskledin 300, Adgelon, Alflutop, ARTRA, Biartrin, Wantong, Chondroflex, Artiplas, Rumalaya, Rumalon, CONDROnova.

Terms and conditions of storage

Store in a place protected from moisture at a temperature of 10–30 °C. Keep away from children.

Shelf life – 3 years.