Dexpanthenol: instructions for use of cream and ointment. Restoration of the nasal mucosa after vasoconstrictor drops Dexpanthenol instructions for use of the drop

Ointment for external use from white with a yellowish tint to light yellow, homogeneous, with a specific odor.

Excipients: petrolatum - 27 g, liquid paraffin - 10 g, lanolin - 17 g, cholesterol - 0.5 g, isopropyl myristate - 3 g, methyl parahydroxybenzoate - 0.07 g, propyl parahydroxybenzoate - 0.03 g, water - 37.4 g.

20 g - aluminum tubes (1) - cardboard packs.
25 g - aluminum tubes (1) - cardboard packs.
30 g - aluminum tubes (1) - cardboard packs.
35 g - aluminum tubes (1) - cardboard packs.
40 g - aluminum tubes (1) - cardboard packs.
50 g - aluminum tubes (1) - cardboard packs.
60 g - aluminum tubes (1).

black (1) - cardboard packs.
30 g - polymer jars (1) - cardboard packs.
35 g - polymer cans (1) - cardboard packs.
40 g - polymer jars (1) - cardboard packs.
50 g - polymer jars (1) - cardboard packs.
60 g - polymer jars (1) - cardboard packs.
70 g - polymer jars (1) - cardboard packs.
80 g - polymer jars (1) - cardboard packs.
90 g - polymer cans (1) - cardboard packs.
100 g - polymer jars (1) - cardboard packs.
5 g - dark glass jars (1) - cardboard packs.
10 g - dark glass jars (1) - cardboard packs.
15 g - dark glass jars (1) - cardboard packs.
20 g - dark glass jars (1) - cardboard packs.
25 g - dark glass jars (1) - cardboard packs.
30 g - dark glass jars (1) -.
100 g - dark glass jars (1) - cardboard packs.

Source: health.yandex.ru

Description of the active substance Dexpanthenol/Dexpanthenol.

Formula: C9H19NO4, chemical name: R-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide.
Pharmacological group: metabolism/vitamins and vitamin-like products/B vitamins/pantothenic acid derivative;
organotropic agents/dermatotropic agents;
regenerants and reparants.
Pharmachologic effect: stimulating regeneration, anti-inflammatory, dermatoprotective.

Pharmacological properties

Dexpanthenol eliminates pantothenic acid deficiency, has an anti-inflammatory effect, and enhances regeneration processes. In the body, dexpanthenol forms pantothenic acid (an active metabolite), which is a substrate stimulator of the formation of coenzyme A; this coenzyme in the body catalyzes acylation processes, takes part in almost all metabolic processes (tricarboxylic acid cycle, metabolism of fatty acids and fats, proteins, carbohydrates, phospholipids and others), ensures the synthesis of corticosteroids, the processes of choline acetylation with the formation of acetylcholine.

and local use, dexpanthenol is quickly absorbed into pantothenic acid and binds to plasma proteins (mainly albumin and beta-globulin). Stimulates skin regeneration. The eye gel has a high viscosity, which allows for prolonged contact of the drug with the corneal epithelium.

Indications

For topical and oral use: inflammatory diseases of the nose, oral cavity, larynx, respiratory tract (including the condition after tonsillectomy), gastric mucosa, treatment of defects in the uterine pharynx mucosa, paresthesia in neurological diseases. For parenteral use: paralytic ileus, pantothenic acid deficiency in malabsorption syndrome, postoperative intestinal atony.
For outdoor use: burns and wounds, dermatitis, abscesses, bedsores, boils, diaper rash, therapy and prevention of inflammation and cracked nipples during lactation, care for infants.
For eye gel: corneal erosion, keratitis of various origins, eye burns, dystrophic diseases of the cornea, prevention of corneal damage when using contact lenses.

Method of application of dexpanthenol and dose

Orally, regardless of food intake, with a small amount of water: children 100-300 mg per day, adults - 200-400 mg per day.
Parenterally (intravenously, subcutaneously, intramuscularly) - 500 mg per day.
In the form of plates for resorption, dexpanthenol is used at a dose of 200-600 mg per day.
The solution for external use is used for rinsing the throat and mouth, diluted (1:1 with boiled water) or undiluted; for inhalation - undiluted; for rubbing into the scalp - diluted (alcohol or water 1:3) or undiluted.
Cream or ointment is applied to the affected area of ​​the skin once a day; applied as a compress to the nipple area; when treating defects in the mucous membrane of the uterine pharynx - once or several times a day.
Conjunctivally: 3 – 5 times a day (depending on the severity and severity of symptoms) 1 drop.
If you miss the next use of dexpanthenol, you must do it as you remember, the next time after the set time from the last use.
Therapy of poorly healing skin grafts and trophic ulcers must be carried out under medical supervision. During eye gel therapy, you should not wear soft contact lenses (if you do use them, they should be removed before using the drug and put back on no sooner than after 15 minutes). The drug should be used with caution in patients with chronic renal failure.

Contraindications for use

Hypersensitivity; for parenteral use – mechanical intestinal obstruction, hemophilia.

Restrictions on use

Chronic renal failure.

Use during pregnancy and breastfeeding

It is possible to use dexpanthenol during lactation and pregnancy, but only according to indications.

Side effects of dexpanthenol

Allergic reactions: itching, urticaria; for eye gel - burning sensation, transient blurred vision, eye irritation.

Interaction of dexpanthenol with other substances

When using additional local treatment, the intervals between the use of the eye gel and other drugs should be at least 5 minutes (the gel should be used last). When parenteral use of dexpanthenol is combined with barbiturates and antibiotics, the possibility of allergic reactions increases.

Overdose

No data.

Trade names of drugs with the active ingredient dexpanthenol

Source: xn——8kceunaflgjrqyoqfbei8dxl.xn—p1ai

Clinical and pharmacological group:  

Alpha adrenergic agonists

Anticongestants

ATX:

R.01.A.B Sympathomimetics in combination with other drugs (excluding corticosteroids)

Pharmacodynamics:

Combined drug.

Xylometazoline

An imidazoline derivative, an α-adrenergic agonist, constricts the venous vessels of the nasal mucous membranes: swelling, exudation, and hyperemia are reduced. Facilitates nasal breathing during rhinitis. The effect occurs within a few minutes after application and lasts for several hours.

Dexpanthenol

Vitamin B, a derivative of pantothenic acid. In the body it turns into pantothenic acid, which is part of coenzyme A, due to which it participates in the processes of acetylation, the synthesis of acetylcholine, porphyrins, and glucocorticoids. Accelerates cell mitosis, increases the strength of collagen fibers. It has a metabolic, regenerating and anti-inflammatory effect.

Pharmacokinetics:

The drug is for local use and does not have a systemic effect on the body.

Indications:

Used to treat acute allergic rhinitis, sinusitis, hay fever. Used to reduce swelling of the nasopharyngeal mucosa in otitis media and to prepare the patient for diagnostic procedures in the nasal passages.

Contraindications:

Glaucoma, chronic and atrophic rhinitis, severe cardiovascular failure, individual intolerance, children under 6 years of age.

Carefully:

Angina pectoris, diabetes mellitus, prostatic hyperplasia, hypersensitivity.

Directions for use and dosage:

As a nasal spray with a metered pump, one spray into each nasal passage 3-4 times a day.

Side effects:

With frequent and long-term use:

local manifestations: swelling of the nasal passages, sneezing, burning and hyperemia of the conjunctiva, transient visual disturbances;

systemic manifestations: lethargy, vomiting, increased blood pressure, dizziness, insomnia, depression.

Allergic reactions.

Overdose:

Most often it manifests itself in children (with accidental ingestion) in the form of systemic disorders: hypothermia, bradycardia, hyperhidrosis, impaired consciousness (lethargy, stupor, coma).

Anticholinergic symptoms: unsteadiness, flushing, shortness of breath, hypotension, depression (loss of consciousness) or hyperstimulation (convulsions, hallucinations) of the central nervous system.

Treatment: drug withdrawal, symptomatic therapy.

The effectiveness of the drug decreases in acute colds.

Instructions

Source: www.lsgeotar.ru

Indications for use

Use is indicated in the following cases:

• For burns
• For cracked nipples
• For diaper rash in newborns
• Indicated for use in dermatitis
• Used for hands and eyes (in the ophthalmological field), if there are wounds that do not heal for a long time
• Suitable for external and oral use for various lesions of the oral cavity, nose, larynx, gastric mucosa, inflammatory processes in the respiratory tract, paresthesia in neurotic disorders
• What does it help with when taken orally – intestinal atony, lack of vitamin B5 in the body, paralytic ileus
• It should also be applied externally for abscesses, bedsores, boils, and defects in the mucous membrane of the uterine pharynx.

Composition and release forms

Dexpanthenol ointment 5% consists of the active ingredient, as well as additionally: cosmetic petroleum jelly, almond oil, ethanol, liquid paraffin, lanolin, water.

Dexpanthenol gel additionally contains dimethyl sulfoxide, ethanol, pure water, glycerin, and carbomer.

Spray, additionally: sea salt, clean water, potassium hydrogen phosphate.

Solution for injection - sodium chloride, water for injections, potassium dihydrogen phosphate.

Dexpanthenol e - in addition to the working substance, the composition includes vitamin E. auxiliary: soft white paraffin, macrogol, ethanol, benzyl alcohol, diethanolamine, pure water, cosmetic paraffin, stearic acid.

The cream is a white viscous, opaque substance in aluminum tubes of 25 or 50 grams. The ointment has the same consistency and is packaged in 25 or 50 grams. In the form of an aerosol for spraying in metal cans, the eye gel is transparent, odorless, homogeneous, 15 grams per tube. The cream and ointment are produced in a consistency of 50 mg of the working component per 1 gram of product in a tube. Solution in injection form. Drops are not released.

Medicinal properties

The medication has a pronounced anti-inflammatory and regenerating effect on tissue. This is a derivative of the B vitamin - pantothenic acid, vitamin B5, and is not a hormonal drug. After superficial application, the product turns into its active vitamin form and stimulates reparative processes in the affected tissue areas.

Cream or ointment – ​​which is better? Both forms of release are well accepted by the body. Does the product interact with hormones or not? Joint use with hormonal ointments is not advisable.

Mode of application

Orally 200 – 400 mg per day. Children - from 100 mg to 300 mg per day. Solution for external use: for rinsing the mouth should be diluted in half in an equal ratio with water, for the scalp 1 to 3, for inhalation the solution should not be diluted.

Dexpanthenol 5% in external form (cream or ointment) is applied topically once a day, not washed off. The gel is also used, but with a frequency of 2-3 times a day. The aerosol is used intranasally. Children from 6 years old and adults 1-2 injections into each nostril 2-3 times a day. For newborns with diaper rash, it is necessary to first wash the affected area, wipe the skin dry, and only then apply the product. Infants usually tolerate the medication well.

During pregnancy and breastfeeding

During pregnancy, dexpanthenol is approved for use in external form. During lactation, if there are cracks in the nipples, a few drops of ointment or cream should be applied after feeding the newborn. The medication must be washed off before feeding.

Contraindications and precautions

Intolerance and hypersensitivity. Parenteral – intestinal obstruction or the presence of hemophilia.

Care should be taken to store the medicine so that children do not find it.

Cross-drug interactions

Antibiotics and barbiturates potentiate the occurrence of allergies.

Side effects

Local or systemic allergies rarely occur.

Analogs

Micropharm LLC, Russia

average price– 240 rubles per package.

One of the analogues of dexpanthenol. Panthenol cream has the same wide range of release forms and range of uses.

Pros:

• Variety of release forms
• Safe product.

Minuses:

• There are cheaper analogues
• Not suitable for everyone.

Grenzach Productions, Germany

average price in Russia – 590 rubles per package.

Bepanten plus is a combination of panthenol with chlorhexidine. Bepanten Plus copes well with diaper rash, burns and healing wounds.

Pros:

• Bepanten plus has a combined composition
• Those who have used Bepanten Plus note good effectiveness.

Minuses:

• There is a Russian cheaper analogue
• The price is not suitable for everyone.

Aqua Maris® spray is an isotonic solution (that is, it is ideal for the body, since the concentration of salt in it corresponds to its level in human blood plasma), and a convenient dispenser provides optimal irrigation and hydration of local areas of the nasal mucosa, without intensive rinsing. Therefore, it can be used every day, especially during outbreaks of colds.

The nasal mucosa is designed in such a way as to constantly filter the inhaled air. For this purpose, nature has provided it with special “microcilia”, which, making rhythmic wave-like movements, prevent the settling of pathogenic viruses and bacteria. Nasal mucus contains antiviral components, envelops and neutralizes trapped microbes. Thanks to the presence of useful microelements in the composition, Aqua Maris® supports the normal physiological functioning of the nasal mucosa under any unfavorable external circumstances (in winter or in an air-conditioned room). Zinc and selenium increase local immunity. Calcium and magnesium stimulate the motor activity of “microcilia”. Iodine and sodium chloride normalize the production of nasal mucus and also produce an antiseptic effect. Any oil-based nasal drops or ointments stick the “microcilia” together, disrupting the natural processes of air purification, clog the ducts of the mucus-producing glands, and can cause side effects such as a burning sensation, increased production of nasal mucus, or even swelling of the mucous membrane. Therefore, for the purpose of prevention, doctors recommend using Aqua Maris® - a modern remedy that supports the body's defenses without increasing the drug load and without changing the normal functioning of the mucous membrane.

Hardening is an accessible and common method of prevention. But we must take into account that all children naturally have different abilities to develop immunity, so in some cases, during hardening, an unpredictable reaction of the child’s body may follow. And the hardening process itself is fraught with difficulties, and prevention with Aqua Maris® spray takes no more than 30 seconds and requires minimal effort on the part of both mother and child.

For prevention, it is preferable to use the Aqua Maris® spray form, since in this case the nasal cavity is not washed, but rather irrigated (during irrigation, a mechanical spray dispenser gently sprays a solution of sea water over the surface of the nasal cavity). In a little more detail, when breathing, viruses enter “shallowly” and are located near the vestibule of the nose. In this case, there is no need to rinse; you just need to irrigate and remove viruses from the local surface. In addition, the compact size of the spray allows you to take it with you and use it at any time when the need arises. And you need to rinse your nose first of all to remove excess mucus, which interferes with normal breathing during a runny nose. In this case, aerosol forms are more suitable - Aqua Maris® Norm or Aqua Maris® Baby Intensive Rinse.

Aqua Maris® contains purified sea water, saturated with beneficial minerals and trace elements that can restore the protective functions of the nose. Zinc and selenium increase local immunity of the mucous membrane. Calcium and magnesium stimulate the motor activity of ciliated cells, as a result of which pathogenic viruses and bacteria cannot gain a foothold on the mucous membrane and cause inflammation. Iodine and sodium chloride normalize the production of nasal mucus and also produce an antiseptic effect. One of the main features of Aqua Maris® spray is precisely the moisturizing of the nasal mucosa. The safety and effectiveness of prevention has been proven by numerous studies by leading Russian specialists at various medical institutions: Russian State Medical University named after. N.I. Pirogov, Institute of Ear, Throat, Nose and Speech, St. Petersburg, Department of Health of Moscow, Scientific Center for Children's Health of the Russian Academy of Medical Sciences, Moscow, Center for Hygiene and Epidemiology, Moscow, Research Institute of Hygiene of the Ministry of Health of the Russian Federation, Novosibirsk, FPPS KSMA, Kemerovo. You can find out more about this information on our website.

Aqua Maris® spray should first be used after visiting public places, since the air in them is saturated with pathogenic microorganisms. In addition, there is a high risk of contact with ARVI carriers. Therefore, removing viruses and bacteria from the surface of the mucous membrane after such walks is a particularly important point! If possible, it is better to do this before visiting crowded places (kindergarten, school, metro, clinic, etc.) to maintain the mucous membrane in “combat readiness”.

A saline solution, apart from water and ordinary table salt, does not contain additional beneficial microelements. The water for the production of Aqua Maris® is obtained in the area of ​​the Adriatic Sea Biosphere Reserve; it contains 7-14% more useful trace elements and minerals* necessary for the full functioning of the nasal mucosa, compared to ordinary sea water. Zinc and selenium increase local immunity of the mucous membrane. Calcium and magnesium stimulate the motor activity of ciliated cells, as a result of which pathogenic viruses and bacteria cannot gain a foothold on the mucous membrane and cause inflammation. Iodine and sodium chloride normalize the production of nasal mucus and also produce an antiseptic effect. Aqua Maris® acts directly on the nasal mucosa, helping to maintain a normal, physiological state. Therefore, preventing colds and runny nose with Aqua Maris® is more effective than using saline solution.
*-Ion chromatographic method development for monitoring of seawater quality used in over-the-counter pharmaceutical industry. Tomislav Bolanča, Štefica Cerjan-Stefanovič, Melita Regelja, Danijela Štanfel. Journal of Separation Science, Volume 28, Issue 13, 2005.

It is advisable to use Aqua Maris® spray a few minutes before going outside.

An air humidifier is a thing that is useful in everyday life. Yes, it indirectly helps moisturize the nasal mucosa. But you cannot pour sea water (it is the one that has a positive effect) into a humidifier, and its effect will end as soon as you find yourself outside the house. Aqua Maris® spray irrigates the mucous membrane with sterile sea water, saturating it with beneficial microelements and helping to restore its protective functions. You will agree that this is beyond the power of a humidifier!

Sea water must be diluted, since in its “natural” state it has an excessively high concentration of salts. By diluting seawater with distilled water, it is artificially brought to an “isotonic” state, at which the concentration of sodium chloride is 0.9%, which corresponds to the level in human blood plasma. It is upon contact with an isotonic solution that the nasal mucosa “feels” most comfortable and physiological. The water in the Aqua Maris® spray, taken from the cleanest areas of the Adriatic Sea, is especially rich in beneficial microelements, as proven by a study published in the Journal of Separation Science. In these places there are 7–14% more microelements and minerals than in other seawater bodies.

Aqua Maris® cannot be replaced with water and salt, since in this case only a solution of sodium chloride (table salt) is obtained. When preparing at home, it is almost impossible to accurately select the proportion of salt and maintain sterility, so there is a risk of doing more harm to the mucous membrane than good: the wrong concentration can cause swelling or even a burn of the mucous membrane. Aqua Maris® has a unique composition of microelements obtained from the water of the Adriatic Sea - one of the cleanest bodies of water on the planet. Zinc and selenium increase local immunity of the mucous membrane. Calcium and magnesium stimulate the motor activity of ciliated cells, as a result of which pathogenic viruses and bacteria cannot gain a foothold on the mucous membrane and cause inflammation. Iodine and sodium chloride normalize the production of nasal mucus and also produce an antiseptic effect. The sterility of Aqua Maris® in production is ensured by a special method of filtering sea water, thanks to which it is possible to preserve all useful microelements and remove organic particles (bacteria, substances of plant and animal origin) without the use of aggressive sterilization methods.

Dexpantonol ointment is used for various skin diseases caused by the adverse effects of external factors.

Indications for use

Use is indicated in the following cases:

• For burns
• For cracked nipples
• For diaper rash in newborns
• Indicated for use in dermatitis
• Used for hands and eyes (in the ophthalmological field), if there are wounds that do not heal for a long time
• Suitable for external and oral use for various lesions of the oral cavity, nose, larynx, gastric mucosa, inflammatory processes in the respiratory tract, paresthesia in neurotic disorders
• What does it help with when taken orally – intestinal atony, lack of vitamin B5 in the body, paralytic ileus
• It should also be applied externally for abscesses, bedsores, boils, and defects in the mucous membrane of the uterine pharynx.

Composition and release forms

Dexpanthenol ointment 5% consists of the active ingredient, as well as additionally: cosmetic petroleum jelly, almond oil, ethanol, liquid paraffin, lanolin, water.

Dexpanthenol gel additionally contains dimethyl sulfoxide, ethanol, pure water, glycerin, and carbomer.

Spray, additionally: sea salt, clean water, potassium hydrogen phosphate.

Solution for injection - sodium chloride, water for injections, potassium dihydrogen phosphate.

Dexpanthenol e - in addition to the working substance, the composition includes vitamin E. auxiliary: soft white paraffin, macrogol, ethanol, benzyl alcohol, diethanolamine, pure water, cosmetic paraffin, stearic acid.

The cream is a white viscous, opaque substance in aluminum tubes of 25 or 50 grams. The ointment has the same consistency and is packaged in 25 or 50 grams. In the form of an aerosol for spraying in metal cans, the eye gel is transparent, odorless, homogeneous, 15 grams per tube. The cream and ointment are produced in a consistency of 50 mg of the working component per 1 gram of product in a tube. Solution in injection form. Drops are not released.

Medicinal properties

The average cost in Russia is 122 rubles per package.

The medication has a pronounced anti-inflammatory and regenerating effect on tissue. This is a derivative of the B vitamin - pantothenic acid, vitamin B5, and is not a hormonal drug. After superficial application, the product turns into its active vitamin form and stimulates reparative processes in the affected tissue areas.

Cream or ointment – ​​which is better? Both forms of release are well accepted by the body. Does the product interact with hormones or not? Joint use with hormonal ointments is not advisable.

Mode of application

Orally 200 – 400 mg per day. Children - from 100 mg to 300 mg per day. Solution for external use: for rinsing the mouth should be diluted in half in an equal ratio with water, for the scalp 1 to 3, for inhalation the solution should not be diluted.

Dexpanthenol 5% in external form (cream or ointment) is applied topically once a day, not washed off. The gel is also used, but with a frequency of 2-3 times a day. The aerosol is used intranasally. Children from 6 years old and adults 1-2 injections into each nostril 2-3 times a day. For newborns with diaper rash, it is necessary to first wash the affected area, wipe the skin dry, and only then apply the product. Infants usually tolerate the medication well.

During pregnancy and breastfeeding

During pregnancy, dexpanthenol is approved for use in external form. During lactation, if there are cracks in the nipples, a few drops of ointment or cream should be applied after feeding the newborn. The medication must be washed off before feeding.

Contraindications and precautions

Intolerance and hypersensitivity. Parenteral – intestinal obstruction or the presence of hemophilia.

Care should be taken to store the medicine so that children do not find it.

Cross-drug interactions

Antibiotics and barbiturates potentiate the occurrence of allergies.

Side effects

Local or systemic allergies rarely occur.

Analogs

Micropharm LLC, Russia

average price– 240 rubles per package.

One of the analogues of dexpanthenol. Panthenol cream has the same wide range of release forms and range of uses.

Pros:

• Variety of release forms
• Safe product.

Minuses:

• There are cheaper analogues
• Not suitable for everyone.

Grenzach Productions, Germany

average price in Russia – 590 rubles per package.

Bepanten plus is a combination of panthenol with chlorhexidine. Bepanten Plus copes well with diaper rash, burns and healing wounds.

Pros:

• Bepanten plus has a combined composition
• Those who have used Bepanten Plus note good effectiveness.

Minuses:

• There is a Russian cheaper analogue
• The price is not suitable for everyone.

"Aquamaris Plus" consists of isotonic sea water. This solution contains a large amount of mineral salts and trace elements, which have a powerful anti-inflammatory and healing effect.

When the drug is instilled into the nose, swelling of the mucous membranes decreases and the discharge of thick mucus improves. In addition, the nasal passages are perfectly cleaned of dry crusts and moisturized.

Description

The active ingredient of the medicine is isotonic sea water. The medicine is sold from pharmacies in the form of a spray. "Aquamaris" with dexpanthenol contains such useful substances as:

• potassium;
• magnesium;
• chlorine;
• sulfur.

The drug is supplemented with additional components:

• water;
• dexpanthenol.

"Aquamaris" with dexpanthenol is produced in sterile dark glass bottles, thirty milliliters each. Each tube is equipped with a sprayer, which is tightly closed with a plastic cap.

The shelf life of the drug is twenty-four months. Once opened, it only needs to be used for sixty days. The medication should be kept in a cool and dark place, preferably in the refrigerator.

Before each use, the can should be warmed in your hands to room temperature.

Pharmacological properties

"Aquamaris" with dexpanthenol helps to thin out thick mucus and stabilize its production by the cells of the nasal mucosa. Other useful components, which are also present in the solution, improve the functioning of epithelial tissue and increase immunity.

If rhinitis (runny nose) is provoked by allergic reactions, then thanks to the nasal spray, the sources of the unpleasant condition are eliminated from the nasal mucosa and inflammation is reduced. The medicine can also be used for preventive purposes, to cleanse the nose of dust of various etiologies.

Positive Action

Thanks to the mineral salts and other useful components included in the drug, the spray has a softening effect and neutralizes dryness in the nose. Dexpanthenol is pantothenic acid that helps quickly restore tissue. This component in the human body has a beneficial effect on the skin and mucous membranes. Beneficial effects of provitamin B5:

1. Participates in metabolic processes.
2. Takes part in oxidation.
3. Helps connect acetylcholine and porphyrin.
4. Normalizes metabolic processes in cells.
5. Strengthens fabric strength.

Dexpanthenol has a mild anti-inflammatory effect. A derivative of this component is pantothenic acid, which helps to quickly regenerate the mucous membrane. Without provitamin B5 in the body, the skin cannot function properly.

Indications

According to the instructions for use, "Aquamaris" with dexpanthenol is prescribed both for preventive purposes and to eliminate pathological processes in the nasopharynx and other otolaryngological organs. The main indications for the use of the drug are the following conditions and diseases:

1. Rhinitis (an inflammatory process in the mucous membrane of the nasal cavity, which is manifested by swelling and nasal congestion, discharge of copious mucous secretions from the nose, burning, tickling and scratching in the nasal cavity, deterioration of the sense of smell).
2. Sinusitis (inflammation of the mucous membrane of one or more paranasal sinuses).
3. Colds.
4. For rapid healing of the mucous cavity after surgical interventions on the nasal cavity.
5. For allergies and vasomotor rhinitis.
6. To reduce the likelihood of colds.
7. To eliminate dryness of the nasal mucosa.

In addition, "Aquamaris" can be used for prevention for those people whose respiratory organs regularly experience harmful effects from the outside. This medication is recommended to irrigate the nasal passages of smokers, as well as workers in hazardous industries, in poor environmental conditions.

"Aquamaris" with dexpanthenol during pregnancy is the number one drug during this period. This medication has no effect on the body of the expectant mother and child.

Restrictions

According to the instructions for use of Aquamaris, it is known that it is not recommended for use if you are intolerant to the substances of the drug. In addition, contraindications include age up to one year. But doctors sometimes ignore this restriction and prescribe Aquamaris to newborns; the dosage in this situation may be reduced.

The spray is not a toxic medicine, so the ban on the use of the drug in infants may be due to the lack of practice in sea water therapy for this category of patients.

Mode of application

According to the instructions for use, it is known that the dosage of the medication depends on what the medicine is used for. If Aquamaris is used for therapeutic purposes, the concentration of the active substance will be as follows:

1. Patients from one to seven years of age are prescribed two irrigations four times a day.
2. "Aquamaris" with dexpanthenol for children from seven to sixteen years old is recommended to use two sprays in each nostril, up to six times a day.
3. Adolescents over sixteen years of age and adult patients are prescribed two spray irrigations, up to eight times a day.

The duration of therapy is approximately four weeks. After a short "rest" the course of treatment can be repeated.

For preventive purposes, children and adults are injected into the nasal passages with two doses of the medication four times a day for fourteen days. Children of primary preschool age are recommended to use one injection of Aquamaris twice a day.

It is advisable to rinse your nose at regular intervals; in this case, the pharmacological effect of the drug will be slightly higher.

Adverse reactions

"Aquamaris" with dexpanthenol contains natural substances that are non-toxic. As a rule, the nasal spray is well tolerated by both adult patients and children.

In special situations, with increased sensitivity, certain negative effects may be observed.

Adverse reactions manifest themselves in the form of itching and swelling of the nasal mucosa, and urticaria may also appear around the nasal passages.

All negative effects are eliminated almost immediately after stopping use of the drug.

Interaction

"Aquamaris" with dexpanthenol does not interact with other medications, since it does not have any effect on the body as a whole. The solution can be used in complex therapy, together with antimicrobial, as well as antiviral and anti-inflammatory drugs.

The drug can be used to rinse the nasal passages before using vasoconstrictor drops. Sea water delicately cleanses the nose of mucus and dried crusts.

After irrigation, you should wait about fifteen minutes and then carefully blow your nose. For young patients, the nasal passages are carefully cleaned with a cotton swab.

Sea water, which is included in the structure of the spray, cleanses the nasal cavity well of secretions. The medicine has anti-inflammatory and anti-edematous effects, and dexpanthenol helps to quickly regenerate cells.

Generics

Analogs of "Aquamaris" with dexpanthenol are the following medications:

1. "Aquamaster."
2. "Aqua-Rinosol".
3. "Sialor Aqua".
4. "Nazol Aqua".

Before replacing the original product with a generic, it is recommended to consult a doctor.

Dexpanthenol is an ointment for external use that has a regenerating and metabolic effect, as well as some anti-inflammatory effect.

The active substance is a derivative of pantothenic acid and belongs to the B vitamins.

In tissues, dexpanthenol is converted into pantothenic acid, which is part of coenzyme A. As part of coenzyme A, pantothenic acid takes part in the processes of acetylation, lipid and carbohydrate metabolism, the formation of acetylcholine, porphyrins and corticosteroids.

Dexpanthenol ointment stimulates the regenerative processes of the mucous membranes and skin, accelerates mitosis, increases the density of collagen fibers, and also normalizes cellular metabolism.

When used externally, it penetrates into the deep layers of the skin and systemic blood flow. Metabolized in tissues to form pantothenic acid, which binds to beta globulin.

Composition of Dexpanthenol ointment - 1 g contains the active ingredient - dexpanthenol - 0.05 g. Auxiliary components - cholesterol, petroleum jelly, methyl parahydroxybenzoate (nipagin), petrolatum oil, white petrolatum, isopropyl myristate, propyl parahydroxybenzoate (nipazole), purified water.

Indications for use

What does Dexpanthenol ointment help with? According to the instructions, the drug is prescribed in the following cases:

• violation of the integrity of the skin as a result of mechanical, chemical, temperature effects (sunburns and burns of other etiologies, abrasions, scratches, wounds, bedsores) or after surgery (poorly healing skin grafts, postoperative aseptic wounds);
• skin inflammatory processes, dermatitis, boils, trophic ulcers on the lower extremities, skin care around gastrostomies, tracheostomas or colostomies;
• prevention and treatment of the consequences of exposure to adverse environmental factors on the skin: cold, wind, dampness;
• source of dexpanthenol and neutral fats as protection for dry skin;
• prevention or treatment of inflammation and cracked nipples during breastfeeding.

For children for the treatment and prevention of diaper rash, diaper dermatitis, scratches and minor skin irritation after exposure to sunlight, X-ray or ultraviolet irradiation.

Instructions for use of Dexpanthenol ointment, dosage

The ointment is intended for external use by applying a thin layer to the affected area of ​​the skin and rubbing in with light massaging movements.

When treating an infected skin surface, pre-treatment of the problem area with any antiseptic is required.

When treating cracked nipples in nursing mothers, the surface of the nipple should be lubricated with ointment after each breastfeeding.

For the prevention and treatment of diaper rash and diaper dermatitis in infants, Dexpanthenol ointment is used after water procedures or with each change of linen.

To treat inflammatory processes of the vagina and mucous membrane of the cervix, the ointment is applied to a gauze swab and inserted into the vagina at night once a day.

Side effects

The instructions warn about the possibility of developing the following side effects when prescribing Dexpanthenol:

• Allergic reactions: urticaria, itching.

Contraindications

It is contraindicated to prescribe Dexpanthenol ointment in the following cases:

• individual intolerance to the components included in the composition.

Dexpanthenol in the form of an ointment or cream can be used to treat skin problems in children from birth.

Approved for the treatment of pregnant women according to indications and under medical supervision.

Interaction with other drugs

Dexpanthenol, when used simultaneously, can increase the duration of action of succinylcholine. If it is necessary to simultaneously use other medications on the same area of ​​the skin, it is necessary to maintain a certain time interval between their applications.

The ointment can enhance the therapeutic effect of local antiseptics.

When using the ointment to treat pathologies of the vagina and cervix, it is not recommended to simultaneously use vaginal suppositories or douching. Any drug interactions should be discussed with your doctor.

Analogues of Dexpanthenol, price in pharmacies

If necessary, you can replace Dexpanthenol ointment with an analogue for therapeutic action - these are the following drugs:

1. D-Panthenol,
2. Pantoderm,
3. Panthenol-Teva.

When choosing analogues, it is important to understand that the instructions for use of Dexpanthenol, price and reviews do not apply to drugs with similar effects. It is important to consult a doctor and not change the drug yourself.

Price in Russian pharmacies: Dexpanthenol ointment 5% 30g – from 106 to 168 rubles, ointment tube 5% 100g – from 470 rubles, according to 725 pharmacies.

Store at temperatures up to 25 °C in a place protected from moisture, aerosol - away from heating devices. The shelf life of the ointment is 2 years. Conditions for dispensing from pharmacies - without a prescription.