The action of trigan d. Tablets "Trigan D": what does the medicine help with

Trigan D poisoning is accompanied by severe consequences. Even timely assistance does not always avoid complications.

When used correctly, Trigan D is not dangerous.

Dangerous consequences of poisoning with Trigan D

Trigan D poisoning is quite common. This is because the seemingly harmless antispasmodic, which is prescribed to reduce pain in menstrual syndrome, intestinal colic, spastic constipation and other conditions caused by smooth muscle spasms, has negative side effects. To understand the danger of uncontrolled medication, you should familiarize yourself with its main active ingredients and their effect on the human body.

The composition of the drug and the effect of the application

Instructions for use for the drug indicates that Trigan D is a combination drug and it contains 2 active components:

Paracetamol. A well-known antipyretic drug with a slight antispasmodic effect.
Dicycloverine hydrochloride. A remedy often used to relax smooth muscles in pylorospasm, renal or biliary colic, and other similar conditions.

When these components are combined, Paracetamol enhances the effect of Dicycloverine hydrochloride and the indications for use will be the same as for these two drugs: smooth muscle spasm and slight fever.

Due to the fact that Trigan D combines antipyretic and antispasmodic properties, parents in a pharmacy can advise this drug for a child, as it helps not only with temperature, but also with muscle pain (these symptoms are often found in childhood hyperthermia).

Danger of taking medication

It would seem that the constituent components of the drug are safe and they can even be given to children to drink, but relatively harmless drugs alone, when combined, can cause the following negative effects:

Overdose. Moreover, for the appearance of signs of a minimal overdose, it is enough to take 4 tablets instead of those indicated in the instructions 2 at a time. In some patients, especially in children in childhood and adolescence, even a slight excess of the dosage can cause mild drug intoxication.
Mental addiction. Prolonged and uncontrolled intake of Trigan leads to the fact that a person feels discomfort and vague pain sensations that disappear only after taking the medicine. A person considers himself ill, goes to doctors, trying to establish the cause of pain, but in fact there is a mental dependence on the drug.

From the above, we can conclude that Trigan D is a drug and the main danger is that the drug is dispensed in pharmacies without a prescription.

Side effects

At observance of the dosages recommended by the doctor and at treatment by Trigan no more than 5 days side effects were not noted. With uncontrolled administration of the drug, adverse reactions may occur, similar to those that arise from an overdose:

nausea and vomiting;
dry mouth;
stomach ache;
blurred vision;
mild auditory and visual hallucinations;
dizziness;
subfebrile fever, accompanied by chills;
small cramps of the limbs;
bradycardia (lower heart rate to less than 60 beats per minute).

Abdominal pain is one of the symptoms of an overdose.

Apart from abdominal pain and vomiting, symptoms such as dizziness, mild hallucinations and visual disturbances provoke schoolchildren and adolescents to take additional doses of medication. Unfortunately, dependence on the drug develops quickly, and it is almost impossible to stop using Trigan D on your own. A person "addicted" to Trigan needs the help of a narcologist.

Combination with alcoholic beverages

The instructions indicate that alcohol and the drug are incompatible. But, some teenagers, to enhance the buzz, prefer to drink pills with beer or alcoholic energy drinks. This combination causes great harm to the body and the combination of alcohol with Trigan D often ends in death.

This is due to the following chemical and physiological reactions:

To get a minimum high, you need 4 tablets, which contain about 1 g of Paracetamol (the maximum single adult dose is 500 mg).
When interacting with even a small amount of low-alcohol drinks (0.5 weak beer), Paracetamol forms a highly toxic compound.
The action of the substance obtained when combined with alcohol causes acute irreversible renal and hepatic failure.

The death of a person occurs due to the massive death of kidney and liver cells.

Who should not take medicine

The constituents of Trigan are considered active potent components that are broken down in the liver and almost completely excreted from the body through the kidneys with urine. Because of these features, the drug is contraindicated in the following cases:

individual intolerance to the components;
dysfunction of the liver and kidneys;
diseases of the gastrointestinal tract during an exacerbation;
stomach ulcer;
pregnancy and lactation (the drug is able to penetrate the hemoplacental barrier, and it is also excreted in breast milk);
children under 12 years of age (if the pharmacy recommends Trigan D as a means to reduce fever and pain in young children, then you should be wary of such recommendations);
cardiovascular pathologies;
high intraocular pressure.

Before taking an antispasmodic, you must familiarize yourself with all contraindications.

Reasons for an overdose

For Trigan D, an overdose can be:

Random. This may be due to the fact that the effect of the drug begins only an hour and a half after ingestion. Carefully read the instructions. The patient may decide that the medication did not work and take an additional dose. In addition, there is a group of patients who, when using drugs based on Dicycloverine hydrochloride, do not have an analgesic effect due to resistance to the drug.
Deliberate. Consciously taken a large (4 or more) number of pills to get high. Paradoxically, even people on whom Dicycloverine does not have a therapeutic effect are subject to drug addiction from Trigan.

But, in both cases, exceeding the dose is dangerous for the body and can cause irreversible changes. The severity of the condition is estimated by the number of tablets taken:

4 - slight reversible disorders of body functions.
6-8 - severe damage to the kidneys and liver, the patient may fall into a coma;
10 or more is a lethal dose, which in most cases leads to death.

Signs of a deliberate overdose of medication

A person who is under the influence of high doses of Trigan develops symptoms similar to the manifestation of schizophrenia:

"glazed" look, when a person looks somewhere in the distance and does not react to what is happening;
psychomotor agitation;
inappropriate behavior;
frequent breathing;
palpitations (the number of heart contractions can reach up to 180-200 beats per minute, creating an increased load on the organ);
appearance of visual and auditory hallucinations.

Like the schizophrenic, the Trigan person is unable to distinguish between hallucination and reality. Unlike schizophrenia, the danger of taking high doses of pills is that gradually the excitation is replaced by depression of consciousness, and the patient gradually falls into a coma.

First aid for overdose

When the first symptoms of an overdose appear, you need to call an ambulance

If you suspect accidental or intentional use of high doses of Trigan D need to call an ambulance immediately. If the patient is conscious, then before the arrival of the doctors, you need to do the following:

Rinse the stomach. Give a person to drink 3-4 glasses of water and induce vomiting by pressing the tip of a spoon on the root of the tongue. Repeat the procedure until clear water comes out of the stomach.
Give Activated charcoal, Smecta or other available sorbents.

If the victim is unconscious, lay on his side and make sure that the vomit does not enter the respiratory tract.

All cases of drug overdose are subject to treatment in a hospital.

Consequences of exceeding therapeutic doses

The most dangerous consequences of an overdose include:

the occurrence of renal and hepatic insufficiency;
coma;
fatal outcome.

But even if help is provided in a timely manner, due to the action of the drug, the patient may develop serious mental disorders. Such patients are forced to be under the supervision of a psychiatrist until the end of their lives.

To avoid the dangerous consequences of an accidental overdose, you should carefully study the instructions and do not exceed the recommended dose. And for those who consciously take a large number of pills “for a buzz”, it is recommended to think about whether a few hours of dubious pleasure are worth ruined health.

Video

If used improperly, Trigan D is dangerous for the body! Trigun D is a drug?

The drug belongs to the group of analgesic and antispasmodic drugs. Trigan-d is combined and has the main properties: relieves pain, reduces temperature and relaxes the smooth muscles of the body. It is quickly absorbed in the gastrointestinal tract, so the therapeutic effect occurs already about an hour after ingestion.

Trigan-d - what helps

Trigan-d is used in many pathological conditions:

Pain during menstruation;
Headache;
Migraine;
Toothache;
Various types of spasms of internal organs (hepatic, renal, intestinal colic);
Spasm of the gallbladder with cholelithiasis;
Relief of pain in inflammatory diseases of the gastrointestinal tract (duodenitis, gastritis, colitis, and so on);
Temperature exceeding 38 degrees Celsius;
Arthritis and arthrosis;
Neuritis and neuralgia;
Radiculitis;
Pain in the muscles.

Contraindications for use

Since trigand has a strong effect on the body, not all people tolerate it well. And there are conditions in which it is generally prohibited for use. Here is some of them:

Duodeno-gastric reflux;
myasthenia;
Pregnancy period;
Gastric ulcer decompensated;
Exacerbation of peptic ulcer of the duodenum 12;
Lactation;
Individual intolerance to the components;
Glaucoma;
Exacerbated diseases of the excretory system (kidney stones, glomerulonephritis, and so on);
Age up to 15 years;
Intestinal obstruction.

How and how much to take trigan-d

Trigan-d is available in tablet form, has a rounded shape, often white. Also, with severe pain, you can use the medicine in the form of a solution for injection.

The composition of the drug includes: paracetamol 0.5 g and dicycloverine hydrochloride 20 mg.

A potent remedy must be taken under the supervision of a physician. The dosage and course are highly dependent on the severity of pain and the clinical picture of the disease that provoked them.

The usual reception scheme looks like this:

Trigan-d tablets are taken orally after a meal, while they are washed down with water in sufficient quantities. The adult dose is one tablet up to three times a day. A maximum of two tablets can be taken at a time. The time between doses is about 5 hours. The daily dose for adults is limited to 4 tablets;
In time, you should not take the medicine for more than five days if you need to get rid of pain. To achieve a hypothermic effect, the reception should not be more than three days;
If the pain syndrome is strong enough, then trigan-d is prescribed in ampoules. Staging is performed in the muscle, should not exceed two milliliters at a time. The drug in this form is put no more than 3 times / day. On average, the duration of this course is about 4 days.

Side effects

Side effects found in studies include:

polyuria;
Arrhythmia;
Urticaria, itching, skin rashes, allergic edema;
Decreased appetite;
dry mouth;
Various violations of visual functions;
Changes in blood counts (decrease in sugar, hemoglobin).

They were observed mainly with prolonged use or overdose.

Trigan-d and alcohol

Paracetamol (included in the composition) has a hepatotoxic effect. But against the background of alcohol intake, the negative effect on the liver increases significantly. Therefore, it is obvious that it is contraindicated to mix trigan-d (and any drugs in general) with alcohol-containing liquids. After all, the consequences can be the most unexpected: from ordinary nausea to anaphylactic shock.

Trigan-D

Compound

Trigan-D tablets
Active ingredients (in 1 tablet): paracetamol - 500 mg, dicyclamine hydrochloride - 20 mg.
Inactive ingredients: calcium hydrogen phosphate, talc, starch glycolate, magnesium stearate, sugar, gelatin.

Trigan-D solution for injections
Active ingredient (in 1 ampoule): dicyclamine hydrochloride - 20 mg.
Inactive components: water for injections.

pharmachologic effect

Combined pain reliever. The mechanism of action of Trigan-D is associated with the anticholinergic activity of the components of the drug. The analgesic effect is manifested in spasms of smooth muscles.
Dicyclomine hydrochloride is a tertiary amine with a weak non-selective M-anticholinergic and myotropic antispasmodic action. Shows antispasmodic, antimuscarinic effect (relaxes the smooth muscle elements of the walls of blood vessels and the digestive tract). Does not have the effects of atropine. It is especially effective in diseases of the digestive system that are associated with spasm of the smooth muscle membrane of the intestinal wall (for example, in irritable bowel syndrome).
Paracetamol is a non-steroidal anti-inflammatory drug. Acts in synergy with dicyclomine hydrochloride, increases its effectiveness and accelerates its analgesic effect.
Dicyclomine hydrochloride after oral administration is rapidly absorbed, accumulates in sufficient quantities in the blood plasma after 1-1.5 hours. The half-life is 30-70 minutes. Excreted from the body by the kidneys - approximately 79.5%.
Paracetamol is completely and rapidly absorbed from the digestive tube. The maximum concentration is recorded after oral administration after 30 minutes. The analgesic effect begins after 0.5 hours, and after 2 hours the peak of the analgesic effect is observed.

Indications for use

Symptomatic treatment for abdominal pain:
Colic (renal, hepatic, intestinal);
irritable bowel syndrome with the presence of spastic contraction of the smooth muscle membrane of the intestine;
dysmenorrhea.

May be prescribed for short-term pain relief in neuralgia, sciatica, myalgia, arthralgia, after surgical or diagnostic interventions. It can also be used for antipyretic effect in case of colds.

Mode of application

The recommended regimen for use in adults and adolescents from 12 years of age: 1-2 tablets 2-4 r / day. Take 15 minutes before meals. The maximum single dose is 2 tablets. The maximum daily dose is 4 tablets. In acute pain syndrome, it is prescribed parenterally (intramuscularly), 2 ml (20 mg dicyclamine) 4 r / day.
The course of treatment - no more than 5 days.

Side effects

From the digestive tract: difficulty in swallowing and speaking, thirst, vomiting, decreased mobility and tone of the gastrointestinal tract, dry mouth, constipation.
From the side of the cardiovascular system: tachycardia, arrhythmia, short-term bradycardia.
From the nervous system: dizziness, staggering, drowsiness.
On the part of the eyes: increased intraocular pressure, photophobia, dilated pupils with loss of accommodation.
Others: urinary incontinence, dryness and redness of the skin, allergic reactions, oppression of hematopoiesis.

Contraindications

Obstructive diseases of the urinary system, gastrointestinal tract and hepatic tract;
in case of acute bleeding in case of instability of the state of the cardiovascular system;
reflux esophagitis;
myasthenia gravis;
· glaucoma;
Severe ulcerative colitis
Severe violations of the hepatic and (or) renal functions;
Decompensated cardiovascular insufficiency;
prostatic hypertrophy;
Hypersensitivity to paracetamol and any other of the components of Trigan-D;
diseases of the blood system;
· collapse ;
deficiency of glucose-6-phosphate dehydrogenase;
Age up to 12 years.

Pregnancy

Contraindicated for pregnant women. If the drug is prescribed to a nursing woman, breastfeeding for the period of taking the drug is temporarily stopped.

drug interaction

Potentiate the action of Trigan-D antipsychotics, amantadine, monoamine oxygenase inhibitors, tricyclic antidepressants, benzodiazepines, narcotic analgesics, anticholinergics, sympathomimetics, nitrates and nitrites, corticosteroids.
Reduces the effectiveness of the drug, the simultaneous appointment of antacids. Trigan-D potentiates the action of digoxin.
The hepatotoxicity of Trigan-D is enhanced when taken with barbiturates, rifampicin, alcohol and zidovudine.

Overdose

With an overdose, loss of accommodation, bradycardia, drowsiness, photophobia, arrhythmia are possible.
Treatment: initiation of vomiting, gastric lavage, enterosorbents, drugs that increase conjugation reactions (methionine inside) and drugs that cause the formation of glutathione (acetylcysteine intravenously). If an overdose is suspected, examination and treatment is carried out in a hospital setting.

Release form

Tablets Trigan D, cream or white, round shape, with beveled edges, smooth surface and notch on one side. In a blister - 20 tablets.
Solution for injection Trigan-D, in ampoules of 2 ml, 20 mg of dicyclamine (does not contain paracetamol). In a cardboard box - 5 ampoules.

Storage conditions

At a temperature not exceeding 25°C, in a place away from children and protected from light. Prescription leave. Storage - according to list B. do not use after the expiration date indicated on the package.

Additionally

At high air temperatures, prescribe with caution, since the drug reduces sweating, due to which heat stroke and hyperthermia can develop.
When combined with anticholinergic drugs, confusion, psychosis, disorientation, hallucinations, weakness, euphoria, insomnia, short-term memory loss, dysarthria, coma, ataxia, inadequate emotional reactions, agitation may occur. These symptoms decrease or disappear after 12-24 hours.
With caution (under the supervision of a physician) appoint with a tendency to bronchospasm and lower blood pressure, liver and kidney diseases. The drug can affect the psychomotor state when taken simultaneously with alcohol and drugs that depress the central nervous system. When taking Trigan-D, it is not recommended to drive vehicles and work in hazardous industries.

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Official instructions for the drug Trigan-D.

Attention!
Description of the drug Trigan-D" on this page is a simplified and supplemented version of the official instructions for use. Before purchasing or using the drug, you should consult a doctor and read the annotation approved by the manufacturer.
Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide on the appointment of the drug, as well as determine the dose and methods of its use.

This pain reliever has a combined effect. Due to this, Trigan D is indicated for use in cases where the effect needs to be obtained quickly, and other medicines are powerless. The medicine can be compared with a narcotic substance, but if taken correctly, any side effects can be avoided.

Trigan D action

Doctors show Trigan D for use by many patients. The speed of action of the drug is ensured by its composition. The drug is based on two main substances: dicycloverine and paracetamol. Dicycloverine is responsible for pain relief. The most effective substance copes with spasms in smooth muscles. it is added to the medication in order to accelerate and enhance the analgesic effect.

After taking Trigan, its active ingredients are quickly absorbed and absorbed by the body. Their maximum concentration is observed after about half an hour. By this time, the patient's condition should already be normal. Most of the drug is excreted in the urine, the rest - in the feces.

In what cases is Trigan indicated for use?

The medicine copes well with pain of various origins. But most effectively it eliminates the discomfort that occurs in the organs of the gastrointestinal tract.

The main indications for the use of Trigan are the following problems:

renal, hepatic or;
dysmenorrhea - a purely female disease that manifests itself during menstruation;
irritable bowel syndrome, in which spastic contractions of the smooth muscles of the intestine are observed.

In addition, Trigan D is used for temporary anesthesia for neuralgia, myalgia, sciatica, arthralgia. The drug is also able to cope with common headaches and migraines. It is sometimes prescribed for severe toothaches and during recovery after serious diagnostic measures or surgery.

Even a cold can be treated with Trigan. Paracetamol, which is part of the composition, effectively reduces the temperature in infectious and inflammatory diseases. But this medicine is not suitable for everyone.

The use of the drug Trigan D

Trigan should be taken orally. The dosage in each case is determined individually. But basically, doctors prescribe to drink a tablet two or three times a day. In the most difficult situations, the dose is increased, and two tablets can be taken at a time. In this case, the daily dose should not exceed four pills.

If you start taking Trigan without consulting a specialist, do not forget that you can drink it regularly for no longer than five days. Those people who, for health reasons, are supposed to use the medicine for a longer period, need to control peripheral blood and regularly monitor the functional state of the liver. In case of an overdose, the development of liver failure is possible.

Trigan D - contraindications for use

Sometimes Trigan not only does not help, but also aggravates the general condition. This can be avoided by knowing well the contraindications to the use of the drug. And it is prohibited when:

Like most other painkillers and analgesics, Trigan D should not be given to children under twelve years of age.

Among the drugs, the benefits of which are actively contested, antidepressants are predominantly listed, however, some antispasmodics in the form of tablets - like Trigan-D - also have a bad reputation. This medicine is even classified by people who are far from medical education as drugs that can be easily bought at a pharmacy, but is it really that dangerous? How do these pills affect the body and do they have health benefits?

What is Trigan-D

If you read the reviews and articles on this drug, the first thing that catches your eye is the presence of the word "drug" next to the name. However, Trigan-D tablets are not officially related to the group of narcotic drugs: the negative attitude of consumers and a number of doctors towards them is due to the mass of adverse reactions from the nervous system with an overdose of the drug, the most striking of which is the appearance of hallucinations.

Compound

The active substances of the drug Trigan-D are dicycloverine hydrochloride in the amount of 20 mg per tablet and paracetamol (500 mg). The latter component is familiar to consumers from pain and antipyretic drugs used during colds, viral infections, etc. Paracetamol has the following properties:

analgesic;
antipyretic.

Doctors call dicyclomine hydrochloride or dicyclomine more dangerous: this is a substance that has an antispasmodic effect, belonging to the number of anticholinergics. The main field of application is gastroenterology: dicycloverine hydrochloride is used in patients with irritable bowel syndrome, enuresis, hepatic colic, and other spasms of the digestive system.

Additionally, Trigan-D includes:

starch;
cellulose;
povidone;
silica;
magnesium stearate.

pharmachologic effect

The key function of this drug is the ability to suppress pain, relieve fever caused by the inflammatory process. The main load lies on paracetamol, which acts as an inhibitor of cyclooxygenase processes in the central nervous system and peripheral tissues, as a result of which:

areas responsible for the severity of pain sensations are blocked;
inflammation is reduced;
effect on thermoregulation.

Dicycloverine hydrochloride has a similar effect, but it works with smooth muscle tissue of internal organs, also having an antispasmodic effect. In tandem, the active substances of the pill help to cope with pain of any etiology, reduce body temperature (however, you should not use Trigan-D as an anti-cold remedy). The drug is able to anesthetize in half an hour or an hour - the time it takes to form the maximum level of active substances in the blood.

Regarding the metabolization of paracetamol, which occurs in the liver, it is necessary to clarify that:

Most of the decay products are excreted through the kidneys, about 20% - with feces.
One of the metabolites of paracetamol can be dangerous for the liver and kidneys.

Release form

A carton box containing 10 strips or 2 blisters with small round tablets without relief (excluding the central risk on the front side) is the only option for Trigan-D. The surface of the tablet is smooth, without a shell; when it enters the oral cavity, the tablet immediately begins to slowly dissolve under the influence of saliva. The classic Trigan (only dicycloverine hydrochloride) is available as a solution for intravenous administration.

Indications for use

spasms of smooth muscles of the digestive tract;
colic in the liver, kidneys;
dental pain;
muscle pain;
migraine;
neuralgia;
pain during the menstrual cycle.

It is not excluded the possibility of taking Trigan-D tablets during infectious and inflammatory diseases, in which there is an increase in temperature, but the effect of the drug in this situation will be mild. In the absence of a positive reaction of the body to Trigan-D after taking the first dose, there is no point in adding another pill to yourself: you need to find another antispasmodic.

Instructions for use Trigan-D

The use of this drug should be carried out with the utmost care, since both paracetamol and dicycloverine hydrochloride are substances whose overdose leads to serious consequences. An increase in the daily rate of tablets, especially in relation to dicyclomine, leads to mental disorders. In case of an overdose, it is required to wash the stomach, give the patient an adsorbent, and inject acetylcysteine.

The basic rules for taking Trigan-D are as follows:

You can not drink more than 2 tablets at a time, and the daily norm is 4 pcs.
The classic scheme for the use of Trigan-D is 3 tablets per day with an equal interval between them.
The course cannot exceed 5 days if Trigan-D is used as an antispasmodic, and 3 days if you bring down the fever with this drug.
While you are taking Trigan-D tablets, it is forbidden to drive.

Pregnancy and lactation

In women who are carrying a child and breastfeeding, Trigan-D cannot be used, since the active substances of the tablet penetrate into the bloodstream. It is possible that the doctor may prescribe the drug individually to a pregnant woman at a dosage 50-75% lower than the standard one, but Trigan-D is not the safest analgesic, since it can stimulate uterine tone and lead to impaired fetal development.

Application in childhood

It is forbidden to use Trigan-D even for the purpose of one-time spasm relief by persons whose age is less than 15 years. Individual situations can be discussed with the attending physician, and if the potential benefit outweighs the degree of harm, the specialist will prescribe an individual dosage of tablets and the duration of the course. It is forbidden to give Trigan-D to a child without prior consultation with a doctor.

Use in the elderly

In persons over 50 years of age, Trigan-D can be used as an analgesic, but it is advisable to calculate the dosage of the drug together with the doctor, focusing on the state of the patient's body. Of particular importance here are the liver, kidneys, the hematopoietic system and the heart, which bear the brunt of an overdose of these pills. It is desirable that Trigan-D in old age be taken once.

drug interaction

Combining Trigan-D with other drugs that have the ability to relieve pain and reduce inflammation is prohibited, since they will reinforce each other and give an overdose effect. Additionally, it is undesirable to combine Trigan-D with drugs that affect the nervous system. With regard to other medications, you need to understand that the tandem of paracetamol and dicyclomine:

should not be taken together with anticholinergics, so as not to provoke adverse reactions;
helps to reduce the effectiveness of taking uricosuric drugs;
causes intoxication if combined with stimulants of microsomal oxidation in the liver.

Trigan-D with alcohol

At the time of using this drug, alcohol-containing drinks should not be consumed - one of the negative features of paracetamol is a conflict with alcohol, resulting in toxic damage to liver cells. If the patient already has pathologies of this organ, the danger increases. Combining dicyclomine with alcohol is also not recommended, since this increases the degree of negative effect on the nervous system, provokes memory lapses, hearing and vision disorders.

Contraindications and side effects

Subject to therapeutic doses of the drug and a short course of treatment, the body tolerates Trigan-D tablets well, but even without an overdose, an individual reaction from almost all internal systems is not excluded. With increased frequency, the drug makes itself felt:

decreased appetite, disruption of taste buds, epigastric pain, hepatonecrosis, increased activity of liver enzymes;
hypoglycemia (possible coma);
urticaria, pruritus, Quincke's edema;
psychomotor agitation, problems with orientation, drowsiness, hallucinations;
hemolytic anemia;
pain in the heart;
convulsions;
urinary retention;
potency disorders;
an increase in the level of dioxin in the blood.

In the presence of pathologies of vision, Trigan-D can increase intraocular pressure, therefore it is prohibited for people with glaucoma. Additionally, there are a number of contraindications to the drug.