Nitroglycerin and alcohol: possible death. Co-administration of nitroglycerin and alcohol - possible risks

Nitroglycerin is a compound of glycerol with nitric acid. The drug containing this component can be produced in capsules, tablets or solution. The main action of nitroglycerin is the rapid expansion of blood vessels. It helps to cope with an attack of angina pectoris or acute pain in the heart, eliminates the feeling of suffocation. Children and pregnant women should not take it, and it is also forbidden to combine nitroglycerin and alcohol.

The drug has the following actions:

• carries out blood flow to internal organs, including the heart;
• normalizes the work of the myocardium;
• accelerates metabolic processes in the heart;
• improves the contractile activity of the muscle;
• reduces the degree of damage to the heart in a heart attack.

The drug should be taken carefully, only by prescription, carefully following the instructions: a dose containing 2 grams can be fatal to the human body. The specific dosage depends on individual intolerance.

If negative consequences appear, urgent gastric lavage, intake of an absorbent substance and seeking help from a specialist are necessary. There are common side effects in case of intolerance or slight overdose.

Side effects

The most common adverse reactions are:

Side effects of Nitroglycerin

• headache, dizziness, tinnitus;
• decrease in hemoglobin;
• redness of the neck, face due to blood flow;
• sensation of heat, fever;
• attacks of arrhythmia and increased heart rate, violation of blood pressure;
• insomnia, lethargy;
• nausea, vomiting, diarrhea;
• decreased vision.

This drug is well absorbed, acts for an hour. It is important to remember that pills do not carry out treatment, their purpose is to relieve painful and unpleasant symptoms. To solve the problem of heart disease, an integrated approach and medical examinations are needed. Only a doctor can prescribe a course of treatment.

Combination of alcohol and nitroglycerin

A serious danger is associated with the combined use of nitroglycerin and alcohol. Nitroglycerin has an effect on the central nervous system, alcohol affects the entire body, that is, these two components reinforce each other.

Among the negative effects of combining nitroglycerin with alcohol, there are :

• rapid vasodilation due to taking the drug nitroglycerin can cause a headache, an alcohol-containing drink will only increase the pain;
• for a person with cardiovascular disease, drinking alcohol can create discomfort in the region of the heart;
• the function of the drug is to lower blood pressure, alcohol also affects pressure, together these substances create a risk of cardiac arrest.

Nitroglycerin and alcohol cause irreversible processes in the body. A tablet or capsule of nitroglycerin after alcohol can be taken at least 5 hours later. In the event of a heart attack after taking alcohol, it is strictly contraindicated to drink the drug.

The patient took nitroglycerin along with alcohol - procedure

The interaction of nitroglycerin and alcohol is impossible, and the simultaneous use is so dangerous that it can be detrimental to the body - lead to sudden cardiac arrest. If out of ignorance a person has taken a drug and a strong drink, it is important to help him in time. Immediate call for an ambulance is required.

The severe consequences are:

• blue lips, fingers;
• headache;
• dry mouth, severe nausea;
• fever, weakness, fainting;
• loss of orientation in space;
• convulsions and difficulty breathing.

Self-help to a person before the arrival of doctors is to provide him with a comfortable position and access to fresh air.

If the victim is unconscious, it is necessary to control:

• body position:
• pulse- easier to feel on the neck;
• breath- observe the movements of the chest; listen with your ear to your chest.

Instructions for assisting the victim - it is necessary to put the person on a flat surface, turn his head to the side

Health care

Stopping the heart rate and stopping breathing is clinical death. At this stage, there is a chance to bring the person back to life by carrying out urgent resuscitation. Before the arrival of specialists, this is an indirect heart massage and artificial respiration. Professional first aid consists of the following actions:

After the necessary procedures, the doctor determines the severity of the patient's condition and leaves him in the intensive care unit or sends him to the hospital for further treatment. In most cases, the patient's condition can be normalized.

It is important to remember that drinking alcohol while taking drugs is an unjustified risk that can lead to the most terrible consequences, even death.

A hangover, as you know, is a subtle thing, and manifests itself in different ways. But without exception, all citizens who are prone to alcoholic excesses suffer in the morning from high blood pressure. This is especially dangerous for people suffering from heart disease, including angina pectoris. Nitroglycerin is one of the best known first aid remedies for angina pectoris and high blood pressure. Let's figure out what kind of drug it is and whether it makes sense to take nitroglycerin with a hangover.

Everyone who read Jules Verne's novel "The Mysterious Island" as a child will surely remember how engineer Smith created an explosive of colossal destructive power from improvised natural materials. It was called nitroglycerin. It was discovered in 1847 by the Italian Ascanio Sobrero. Subsequently, Alfred Nobel began to make dynamite and smokeless powder from it. The production and transportation of nitroglycerin are still extremely dangerous processes. The substance explodes from friction, impact, heating even up to 25°C. During the explosion, a huge amount of energy is released, the temperature at the epicenter reaches 4110 ° C.

In addition to being used in military, construction and mining, nitroglycerin has a completely peaceful mission - to save people's lives and health. In medicine, the drug is used in a safe (not blasting) form. Due to the peculiarities of the absorption of nitroglycerin molecules in the human body, this substance has the ability to expand the walls of blood vessels almost instantly after entering the systemic circulation - mostly veins, but also arteries. As a result, blood is deposited in the venous bed, the preload on the heart is sharply reduced, it ceases to go astray and suffer from a lack of oxygen.

Expansion of the coronary arteries also reduces afterload, especially on the left ventricle, which drives blood through the systemic circulation. As a result, a few minutes after taking the drug, blood pressure indicators (primarily diastolic) return to a relative norm, pain and fear of death disappear, the subjective state of the patient improves significantly, although the drug is not able to affect the alcohol intoxication that caused the attack. When wondering whether it is possible to take nitroglycerin with a hangover, one must also remember that, along with the relief of symptoms, it is necessary to cleanse the body as soon as possible of the decomposition products of ethyl alcohol taken in a horse dose the day before.

The mechanism of action of nitroglycerin with a hangover

According to the chemical structure, nitroglycerin is an ester of glycerol C 3 H 5 (OH) 2 and nitric acid HNO 3. The molecule contains three nitro groups, which, when bound to blood proteins, instantly release chemically active free radicals NO. They, in turn, activate the specific enzyme guanylate cyclase, which is responsible for the statics of smooth muscle cells. These are, first of all, the walls of blood vessels, as well as all the hollow organs in which the circulation of physiological fluids occurs. Therefore, nitroglycerin with a hangover can be taken not only with an off-scale tonometer and pain behind the sternum, but also in case of colic in the abdominal organs.

It is no secret that alcohol intoxication can lead to exacerbations of such dangerous diseases as chronic pancreatitis and cholecystitis, cholelithiasis, inflammation of the urinary tract. Here, again, it must be remembered that the temporary elimination of the pain syndrome due to the relaxation of smooth muscles lubricates the clinical picture, but does not eliminate the cause of the pain. In acute pancreatitis or the passage of stones, every minute is precious. So about whether it is possible to take nitroglycerin with a hangover for abdominal pain, it is better to ask a doctor familiar with the anamnesis, and not rely on the advice of friends and reviews on the Internet.

Hangover nitroglycerin - can it be taken orally?

In pharmacies, the drug is available in the form of tablets weighing 0.5 g. They are taken sublingually - put under the tongue and absorbed until the tablet is completely dissolved by saliva. Nitroglycerin is perfectly absorbed through the mucous membrane of the oral cavity and its content in the blood plasma becomes maximum after four minutes, which allows you to quickly provide a vasodilating effect, stop an attack of angina pectoris or lower blood pressure.

When taken orally, a significant part of the drug is destroyed during the initial passage through the liver. The vasolidating effect persists, but it is significantly lower than with sublingual administration.

In addition to lozenges, there are edible and inedible patches that are glued to the oral mucosa. Such administration of the drug is called subbucal and provides a prolonged effect of the drug. Sprays for inhalation have also been developed. In the hospital and in the ambulance, nitroglycerin is administered intravenously, but this practice can hardly be attributed to cases of the use of nitroglycerin with a hangover.

Contraindications and side effects

Is it possible to drink nitroglycerin with a hangover with severe arterial hypotension? This is absolutely contraindicated! Even if alcohol intoxication caused an increase in blood pressure, the drug, being among the potent ones, can lead to a too sharp decrease in pressure and disturbances in the work of the heart.

People prone to tachycardia should not get carried away with nitroglycerin, as it increases the heart rate. It is also worth remembering that the drug provides vasilidation of the veins and coronary arteries, but causes the opposite effect on the cerebral vessels. If you suffer from a headache with a hangover, nitroglycerin can even increase it, is it possible to take such a drug - you be the judge.

There are also cases of individual intolerance to the drug, so experimenting on yourself in a state of severe withdrawal is not the best method.

So is it possible or not

Let's summarize. It is impossible to give a clear answer to the question of whether it is possible to drink the drug nitroglycerin with a hangover. It is certainly indicated for patients with severe pathologies of the cardiovascular system and a tendency to arterial hypertension, but for such people it is better in principle not to allow a hangover, since it poses a real threat to life. Practically healthy people who overdid it the day before with alcohol, the drug will not hurt, but it is unlikely to bring a noticeable investment, but it can add a headache.

Nitroglycerin refers to drugs that require caution when using. It has a high intensity and speed of impact on the body.

Nitroglycerin - characteristics of the drug

Nitroglycerin is a drug that has an antianginal and coronary dilating effect.

Nitroglycerin causes:

1. activation of metabolic processes;
2. increase in the intensity of blood flow;
3. supply of additional oxygen;
4. normalization of cardiac activity;
5. reduction in the area of ​​myocardial damage at risk of a heart attack.

A distinctive feature of the drug is an almost instantaneous effect, relief occurs within 1-2 minutes. The effect of the drug lasts about an hour. A nitroglycerin tablet placed under the tongue immediately begins to dissolve, penetrating into the blood through the capillaries of the mucous membranes.

Chemical composition and action

The main active ingredient is glycerol trinitrate. Glucose, starch, calcium and other components are added to it. The drug should be used strictly on the advice of a doctor.

Dosage forms:

• tablets;
• capsules;
• ampoules with a solution;
• spray;
• drops;
• gum stripes.

Application features

The drug is used in cardiology, as well as, if necessary, urgent relief of pain.

It is prescribed for:

1. angina;
2. ischemia;
3. heart attack;
4. pathologies of the cardiovascular system;
5. exacerbation of pancreatitis;
6. suffocation and in other cases.

Possible Side Effects

Nitroglycerin quickly and effectively relieves pain, prevents heart attacks. But due to the intense expansion of blood vessels, it can cause side uncomfortable disorders.

Most often, patients report:

• dizziness;
• headache;
• pressure surges;
• violation of the heart rhythm;
• vision problems;
• a rush of blood;
• problems with the gastrointestinal tract.

Therefore, nitroglycerin is contraindicated in pregnant women, as well as patients with diagnoses in which a sharp vasodilation is dangerous: glaucoma, intracranial pressure, etc. The drug can only be taken on the recommendation of a doctor, he also calculates the optimal dose.

Nitroglycerin and alcohol - a deadly combination

Nitroglycerin itself is an unsafe drug that has a large number of side effects and contraindications.

It requires careful attention when taken, an overdose can provoke a sharp drop in pressure, up to collapse.

The danger increases many times with the combination of nitroglycerin and alcoholic beverages.

Alcohol combined with nitroglycerin is a killer combination.

Ethanol is a poison in itself, and the interaction with it of drugs designed to affect the human body can lead to the most unfortunate consequences.

Alcohol combined with nitroglycerin is one of the most dangerous combinations that can cause death in a person.

Video: Nitroglycerin application indication

In the first-aid kit of every person suffering from heart pathologies, there is "Nitroglycerin". This drug has been produced by pharmacological companies for a long time, and during this time many have managed to verify its effectiveness. On the other hand, holidays and celebrations are obligatory present in the life of all "cores". Therefore, they often have the question, is it possible to combine alcohol and Nitroglycerin?

The heart is considered one of the main structural elements of the human body. When his work fails, the malfunction is reflected throughout the body. Various factors can provoke problems with the cardiovascular system. This is the use of alcoholic beverages, and smoking, and a sedentary lifestyle. Doctors identify a huge number of so-called provocateur factors. To prevent and treat heart failure, doctors suggest using "Nitroglycerin".

Among its main pharmacological properties, it should be noted:

1. Normalization of the myocardium.
2. Providing the heart muscle with additional oxygen.
3. Pronounced vasodilating effect.
4. Restoration of metabolic processes in the heart.

Previously, the drug was sold exclusively in the form of tablets. There was no need to take the pill with water, just put it under the tongue. Today, the drug is sold both in the form of a spray, and in the form of stickers on the gums, as well as as a solution for injection. After entering the body, the drug begins to act within two minutes. Its therapeutic effect can last for about an hour.

Interaction with alcohol

After taking therapeutic pills, many patients complain of a severe headache. This symptom fully characterizes the clinical picture after taking nitrate drugs. Its appearance is due to a sharp expansion of the vascular beds, including in the brain. Such a vasodilating effect entails a drop in blood pressure, hot flashes and flushing of the skin. Therefore, the drug is not recommended for patients with high ICP, vascular insufficiency and cerebral hemorrhage. It is also better to refuse treatment for people with glaucoma, severe atherosclerosis and during pregnancy.

How do "Nitroglycerin" and alcohol behave? This drug is categorically incompatible with alcoholic beverages. Their components are dangerous for the human body. Therefore, with simultaneous use, the likelihood of irreversible, and in some cases even fatal consequences increases several times. Sometimes doctors prescribe to patients a constant intake of Nitroglycerin tablets. In this case, it must be remembered that drinking alcohol is permissible after at least 5 hours.

If during a holiday or celebration, when strong drinks were taken, an angina pectoris attack suddenly occurred, it is forbidden to use heart pills. First of all, you need to call a team of medical workers. After that, provide the victim with a constant supply of fresh air, if necessary, unfasten the buttons on the clothes, loosen the tie.

Lethal dosage

"Nitroglycerin" within a few minutes stops the pain attack due to its lightning-fast effect on the nervous system elements. Abuse of tablets or exceeding the prescribed dosage can lead to death.

An overdose usually provokes a sudden drop in blood pressure. As a result, the patient develops convulsions, tachycardia, nausea. Sometimes the lips turn blue, shortness of breath occurs, the temperature rises. If these symptoms appear, you should seek medical help, rinse the affected stomach with warm water.

There is no so-called lethal dosage for this drug. The strength of the therapeutic effect shown may depend on many factors. For example, one patient will feel unwell after three pills, and another will feel good after 10 pills. However, according to some sources, a dosage of 100 mg of the drug per kilogram of body weight is considered fatal.

Likely consequences

Cardiologists warn their patients that Nitroglycerin and alcohol should not be taken together. The interaction of the substances that make up the drug with ethanol can lead to sad consequences. If there is an urgent need, you can drink strong drinks only after 5-6 hours. On the other hand, it is better to take the medicine after alcohol after the final sobering up. If the patient's clinical picture is supplemented by a hangover syndrome, it is necessary to wait for the condition to normalize.

Why do doctors give such recommendations? First of all, ethanol several times enhances the side effects of taking Nitroglycerin. These are, first of all, anemia, headaches and a decrease in blood pressure. The attending physician should tell in more detail about the negative consequences. Also, such information can be obtained from the annotation to the medication.

On the other hand, the active ingredients of the tablets increase the toxicity of strong drinks and even lower its lethal dosage. As for the first question, it usually concerns people who use counterfeit products. If the drink was already made in violation of the technology, low-quality components were used in it, it can be harmful to health. And "Nitroglycerin" only multiplies this kind of negative effect.

The second question concerns the majority of conscientious citizens. For example, a person after a bottle of alcohol first feels a slight degree of intoxication, and in the morning he tries to find a cure for a hangover. With the simultaneous use of "Nitroglycerin" and alcohol, you can not live up to a hangover.

Summing up

Is it possible to combine "Nitroglycerin" and alcohol? The opinion of most modern cardiologists on this issue is unanimous. They argue that it is impossible to combine ethanol with the drug. Alcohol in small quantities is allowed approximately 5 to 6 hours after taking the pill.

Otherwise, the likelihood of hazardous consequences for human health increases. They can be very diverse, starting with a banal malaise and ending with a fatal outcome. In addition, Nitroglycerin should be taken only in the dosages recommended by the attending physician. Even a slight excess of them can also provoke an undesirable effect.

Absolutely any drug, and "Nitroglycerin" in this matter is no exception, in combination with alcoholic beverages can cause consequences that are dangerous to the patient's health. This cardiac drug sometimes provokes the development of a severe coma, adversely affects the functioning of the myocardium. That is why doctors do not recommend mixing alcohol with therapy, including if the pain has become very strong and taken the person literally by surprise. When this kind of situation arises, it is better to call a team of medical workers and strictly follow their recommendations to eliminate the ailment.

Means and is widely used in cardiology for the relief of symptoms of angina attacks. It is produced in the form of tablets and spray and is an indispensable tool in the first aid kit of every "core". Consider further the indications and effects of the active substances of the drug on the body, and the combination of Nitroglycerin with alcohol.

Nitroglycerin has an immediate vasodilating effect

The main active ingredient of this drug is nitroglycerin, which is obtained by the chemical combination of glycerol and nitric acid. Nitroglycerin is widely used in cardiology, as it has an instant vasodilating property. In addition, when taking the drug, the following effect is noted:

• Functionality normalization
• Reducing the area of ​​damage to the heart muscle in a heart attack
• Acceleration of metabolic processes in the heart
• Instant expansion of blood vessels and an increase in blood flow to all organs
• Provides oxygen to heart tissues
• Normalizes the contractile function of the heart

Until recently, Nitroglycerin was produced exclusively in tablet form. They should be used one at a time under the tongue during a heart attack. If after 5 minutes there is no relief, you can take another pill, but not more than 4-5 pieces at a time.

If, after taking the third Nitroglycerin, relief does not occur, this indicates an onset, so you should immediately call an ambulance. Modern medicine offers this drug in the form of drops.

In chronic heart disease, cardiologists recommend carrying Nitroglycerin tablets or drops with you.

But drops are taken exclusively with sugar, so it’s still easier to get by with pills on the road. According to the impact of any dosage form of this drug is absorbed very quickly and begins to act. Therefore, Nitroglycerin is considered the best remedy for getting rid of pain and "lack" of air during a heart attack.

The mortal danger of the drug

Two grams - about the same amount of nitroglycerin can kill a person

Nitroglycerin, like any drug, is not recommended to be taken without a doctor's prescription. In addition to indications, it has contraindications and precautions. In order not to harm your health, it is important to follow the dosage.

Each organism is individual, and therefore the lethal dose for each may be different. On average, this is 2 grams of the drug. In addition to death, there are a number of side effects:

• Spasms of cerebral vessels
• Rush of blood to face and neck
• Migraines, dizziness, tinnitus
• Seizures
• Nausea and vomiting, indigestion, diarrhea
• Sharp
• Decreased sharpness and visual acuity
• Violation of the central nervous system - insomnia, apathy, emotional indifference

If one of the described symptoms appears, it is required to wash the stomach, drink an absorbent drug and consult a doctor.

Most often, side effects or poisoning with nitrate drugs are observed in "lazy" patients. For chest pains, it is easier for them to take a Nitroglycerin tablet than to visit a cardiologist, get tested and undergo a full medical examination. You should know that this drug only relieves symptoms, but does not cure.

For example, during an attack, a pill normalizes the heart rate, relieves pain, but does not have a therapeutic effect. In order to cure heart disease, a long course and an integrated approach are needed. And only a specialist can prescribe it, based on the results of the examination of each patient individually.

It is important to keep the medicine out of the reach of children, as their curiosity can end in failure.

It is also worth considering that with prolonged use, this drug is addictive and ceases to work. That is, it does not help with pain, but at this time it simply poisons the body.

Why nitroglycerin can kill and not save, see this video:

Interaction between alcohol and nitroglycerin

Nitroglycerin should not be taken with alcohol. By itself, alcohol "slows down" many intracellular processes and has a detrimental effect on the body.

Nitroglycerin can also negatively affect life processes, but the combination of these two substances can be a deadly combination, especially for patients with a weak heart.

If circumstances are such that after glycerin you have to drink an alcoholic drink, then this can be done no earlier than 5 hours after taking a Nitroglycerin tablet.

If there is alcohol in the body, and suddenly it starts, the nitrate drug should not be taken in any case. It is necessary to immediately call the doctors.

As an aid, you need to seat the patient, unbutton his top buttons (tie, scarf) so that he can breathe fully. Be sure to open the windows, or take the person outside until the ambulance arrives.

Consequences of drinking alcohol after Nitroglycerin

It is forbidden to use nitroglycerin along with alcohol

The chemical compounds that make up Nitroglycerin can change the properties of alcohol and significantly reduce its lethal dose. For example, if usually after a certain dose of alcohol a person felt only intoxication, then in combination with pills it may occur.

Alcohol, which is an integral substance in alcoholic beverages, several times enhances all the side effects that may occur as a result of the use of Nitroglycerin - tachycardia, disruption of the gastrointestinal tract, headaches and others.

In conclusion, I would like to note that Nitroglycerin is one of the most valuable drugs in cardiology. He is one of the few who can relieve a heart attack within one or two minutes, by expanding blood vessels and accelerating blood circulation. Thus, oxygen with blood enters all vital organs.

When taking drugs of similar effects and composition, it is important to take into account their "strength".

They have a certain number of side effects, so it is necessary to use nitrate agents with great care and in no case should they be combined with alcoholic beverages.

The worst thing that can happen is instant cardiac arrest, but besides this, nitroglycerin and alcohol cause irreversible processes in the body that can leave a person disabled. Given all these factors, before using the drug, it is necessary to consult the attending physician.