What foods contain methylsulfonylmethane. Possible Side Effects of Methylsulfonylmethane

Compound

Methylsulfonylmethane, microcrystalline cellulose, amorphous silicon dioxide, croscarmellose, magnesium stearate, stearic acid, hydroxypropyl methylcellulose, hydroxypropyl cellulose, polyethylene glycol, titanium dioxide

Description

MSM - to reduce inflammation in the joints, swelling, reduce pain, quick recovery of joints and muscles, including after training

Methylsulfonylmethane, an organic sulfur-containing compound, is a key metabolite of dimethyl sulfoxide (DMSO) and contains 34% organic sulfur. MSM is part of many endogenous proteins (including connective tissue proteins - collagen, elastin, keratin), hormones and other metabolically active compounds. MSM has anti-inflammatory and analgesic effects.

Numerous foreign studies have shown that MSM promotes faster recovery of joints and muscles after exercise, has anti-inflammatory, antioxidant, anti-allergic properties. MSM is involved in the formation of connective tissue, collagen biosynthesis, which contributes to skin elasticity and muscle strengthening, promotes wound healing, and has a positive effect on skin condition and hair growth.

MSM has been researched for its beneficial properties in the treatment of arthritis and other joint inflammation complications. The results of studies conducted by American scientists showed that with targeted intake of MSM as a biologically active food supplement in arthritis patients, the inflammatory process and the rate of cartilage destruction were significantly reduced.

Researchers say that MSM, when dosed correctly, can help:

Reduce inflammation in the joints;

Reduce swelling and stiffness of the joints;

Improve blood circulation and cell viability;

Relieve pain associated with inflammatory processes;

Break down calcium deposits.

1000 mg methylsulfonylmethane (MSM) contributes to:

Reducing inflammation in the joints and reducing pain;

Reducing swelling of the joints,

Rapid recovery of joints and muscles after training.

2 tablets contain - Methylsulfonylmethane - 1000 mg (1 gram)

Tablets are round, biconvex, white-coated, on a break of white color

Selling Features

Without a license

Special conditions

Indications

as a biologically active food supplement containing methylsulfonylmethane and helping to reduce inflammation in the joints and reduce pain, reduce swelling of the joints, quickly restore joints and muscles after training, improve the condition of the skin, hair and nails. Supports joint mobility and flexibility.

Contraindications

Individual intolerance to the components of the product, pregnancy, lactation.

Should You Take MSM? This compound is known to be a reliable remedy for reducing muscle pain and speeding up recovery. In this article, we will cover all the potential benefits of this dietary supplement.

Methylsulfonylmethane, or MSM (MSM) is a common food supplement. MSM has gained a lot of popularity in the bodybuilding industry over the past few years, as many large-scale studies have shown that it provides a host of health and performance benefits. In particular, MSM has been shown to reduce exercise-related pain and inflammation, reduce oxidative stress, and enhance recovery.

In this article, we analyze the available data on the uses and benefits of MSM to help you decide whether to include this supplement in your sports nutrition stack.

What is MSM?

Methylsulfonylmethane (MSM) is a naturally occurring chemical compound that originates from the sulfur in the earth's crust and diffuses into aquatic environments such as oceans, rivers and lakes, from where it then enters the soil. MSM contains organic sulfur, which is considered an essential dietary mineral. Sulfur is the third most abundant element in the human body in relation to body weight.

Due to its small molecular size and high ability to penetrate cell walls, MSM travels from the soil to plants and then to the animals that feed on them.

That's why MSM is found in most natural plant foods - fruits, vegetables, and grains. MSM can also be taken in supplement form, making it easier to get a higher dose of MSM than is possible with natural sources alone.

How MSM works

As a sports supplement, MSM is used to reduce pain and inflammation after exercise, and to improve overall performance. MSM is often included as an additional ingredient in supplements. As a result of research, it was concluded that in combination these products give a greater effect than when consumed separately.

MSM also works as an antioxidant, which reduces the harmful effects of free radicals in the body. This very small molecule moves easily within and between cells, which allows it to spread throughout the body and have a positive effect on the tissue and cellular level.

Proven Benefits of MSM

The positive effects of MSM supplementation on pain reduction and functional improvement of joints and ligaments are supported by both clinical and randomized controlled studies.


One study tested 1.5 and 3 gram daily doses of MSM for 30 days. It was found that when taking MSM, the subjects recovered faster from strength exercises and noted a decrease in muscle fatigue and soreness.

A recent 2017 meta-analysis of MSM studies refutes earlier suggestions that the benefits of MSM are not clinically relevant. The authors of the study found that the benefits of MSM for health and productivity are well documented and substantiated in various sources.

In recent research, the focus has shifted to examining the benefits of MSM for people with metabolic syndrome.

Does MSM have side effects?

MSM consumption is considered completely safe. The US Food and Drug Administration recognized MSM as a safe food back in 2007.

In the longest study of MSM to date, a 26-week study of the supplement, no side effects were found, even at a dosage of 6 grams per day. However, pregnant and lactating women are not recommended to take MSM due to insufficient research on the effects of MSM on this category of people.

Are there any natural forms of MSM

In fact, it's not uncommon for you to consume MSM as part of your regular meal plan. MSM is found in large quantities in cow's milk, coffee and tea. Natural MSM is also found in tomatoes, corn, apples, raspberries and even beer!

However, the concentration of MSM in natural food sources is relatively low. That's why, as more studies point to the powerful pain-relieving and anti-inflammatory effects of MSM, a synthetically produced product has become widespread.

It has the same properties as natural, which allows you to supplement the diet with a higher dose of MSM without the need to consume unrealistic amounts of food.

In most studies, MSM was taken orally, in a dosage range of 500mg to 3g twice daily. The Recommended Daily Allowance (RDA) is partly determined by the intended outcome of consuming this supplement. For example, in a study of the effectiveness of antioxidant properties and the treatment of osteoarthritis, the dose of MSM ranged from 1.5 to 3 g per day. To improve recovery from soft tissue injuries, it is sufficient to take 50 mg of MSM. The highest reported dose of MSM in the scientific literature is 6 grams per day.

Does MSM interact with other drugs?

When interacting with certain medications, MSM can cause drowsiness and have an effect similar to antihistamines.

MSM occurs naturally in the human body through food and is safe to take as a dietary supplement. MSM provides a wide range of benefits, including improved joint function, faster recovery from exercise, reduced pain and inflammation, and reduced oxidative stress.

The cost of MSM supplements is relatively low and well worth it for people who are looking to reduce inflammation and joint pain and return to normal physical activity. For athletes and bodybuilders, MSM can be a valuable addition to the sports nutrition stack to improve recovery and reduce joint inflammation.

Active ingredients

  • Not indicated. See instructions

Pharmacological action

  • Not indicated. See instructions

Description of the pharmacological action

Promotes regeneration (recovery) of damaged cartilage tissue.
It has an anti-inflammatory effect, relieves pain and tension in the joints, increases their mobility, reduces swelling.
Participates in the formation and improves the trophism of the connective tissue of articular surfaces, tendons, ligaments, synovial fluid, skin, bone tissue, nails, heart valves, blood vessels and mucous membranes of the digestive, respiratory and urinary tracts.
It has a beneficial effect on cartilage metabolism - strengthening anabolic and weakening catabolic processes.
Stimulates collagen synthesis.
Inhibits the activity of enzymes that destroy connective tissue, incl. cartilage.
Improves microcirculation of the vascular bed of periarticular tissues.
Stimulates the synthesis of hyaluronic acid, which provides the lubrication necessary for the functioning of the joints.
Participates in the processes of bone mineralization, regulating calcium balance and favoring the processes of ossification.
It has an antithrombotic heparin-like effect.
Chondroitin sulfate is also necessary for any pathological processes of connective tissue, not only cartilage, but also tendons, ligaments and, of course, skin. Therefore, not only sports doctors should have chondroitin sulfate in their arsenal, but also competent dermatologists and cosmetologists. Unfortunately, the latter very rarely turn to oral cosmetics. Chondroitin sulfate, as well as vitamins A, B, C, E, can be called enteral cosmetic preparations.
Promotes healing of fractures, wounds, erosions, ulcers.
Reduces the concentration of cholesterol in the blood, prevents the accumulation of atherosclerotic plaques on the walls of blood vessels, improves blood circulation.
Methylsulfonylmethane (organic sulfur, MSM) provides the molecular structure of the protein, is part of many amino acids, and is involved in the synthesis of antioxidants, in particular glutathione. Sulfur is necessary for articular tissues, where it is responsible for the stability of cartilage, capsule and ligament tissues. MSM has a positive effect on joint pain, helps restore joint mobility, as well as improve the permeability of cell walls, allowing fluid and substances dissolved in it to more easily penetrate cell membranes. This facilitates the removal of substances such as lactic acid and taxins from the cells and the entry of nutrients and trace elements into the cells. MSM prevents the increase in intracellular pressure, which relieves pain.

Compound

Glucosamine sulfate (from 1500 mg potassium glucosamine sulfate complex) 1100 mg
MSM (methylsulfonylmethane) 300 mg
Chondroitin sulfate sodium (from bovine cartilage) 1200 mg
Sodium 110 mg
Potassium (potassium chloride) 245 mg
Other Ingredients: Gelatin (capsule) and magnesium stearate (vegetable source). Contains shellfish (crab, shrimp, lobster, crayfish).

Indications for use

Inflammatory and metabolic diseases and injuries of the osteoarticular system: osteoporosis, osteochondrosis, fractures, Bechterew's disease, tendovaginitis, bursitis, arthritis, arthrosis, gout, rheumatoid arthritis.
The recovery period after injuries, bone fractures, with the "knee of jumpers" in athletes.
Wound healing effect (postoperative conditions, trophic ulcers).
Increased fragility of nails, hair loss.
Cardiovascular diseases (varicose veins, heart defects, atherosclerosis).
In cosmetology for restoring skin texture, improving tone, smoothing and reducing the number of wrinkles, skin rejuvenation, treatment of hyperpigmentation.

Release form

tablets 1650 mg;

Dosage and administration

Storage conditions

In a dry, dark place, at a temperature not exceeding 25 °C.

Best before date



The description of the vitamin Glucosamine + Chondroitin + MSM is for informational purposes only. Before using any drug, it is recommended to consult a doctor and read the instructions for use. For more information, please refer to the manufacturer's annotation. Do not self-medicate; EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the project does not replace the advice of a specialist and cannot be a guarantee of the positive effect of the drug you are using. The opinion of EUROLAB portal users may not coincide with the opinion of the Site Administration.

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Attention! The information provided in the vitamins and dietary supplements section is for informational purposes only and should not be used as a basis for self-treatment. Some of the drugs have a number of contraindications. Patients need specialist advice!


If you are interested in any other vitamins, vitamin-mineral complexes or dietary supplements, their descriptions and instructions for use, their analogues, information on the composition and form of release, indications for use and side effects, methods of application, dosages and contraindications, notes about prescribing the drug for children, newborns and pregnant women, the price and consumer reviews, or if you have any other questions and suggestions - write to us, we will definitely try to help you.

Methylsulfonylmethane is a drug intended primarily for maintaining fitness and beauty. At the same time, its leading effect is anti-inflammatory. Why this substance has such an unusual combination of properties, you will learn from this post describing the additive MCM-1000 (MSM-1000). Surely you will want to take it too!

MSM-1000 (MSM-1000): composition and form of release

In each capsule:

  • Methylsulfonylmethane - 1000 mg.

Release form: jar containing 120 capsules.

MSM-1000 (MSM-1000): properties

MSM is an organically bound sulfur of natural origin. Sulfur is very important for the formation of joint components as well as skin fibers. In addition, sulfur-containing enzymes produced by the body have a fairly noticeable anti-inflammatory effect and affect the full functioning of the nervous system.

In more detail, then MSM-1000:

  • Accelerates the recovery of joints and ligaments after sports injuries: relieves inflammation, improves metabolic processes, accelerates healing. Some studies also show that MSM has an analgesic effect, that is, an analgesic effect.
  • Improves the condition of the skin, as it promotes the formation of collagen and elastin.
  • Helps to increase attention, improve memory, accelerate thought processes, normalize sleep.
  • Provides faster growth of hair and nails, with long-term use improves their quality.
  • It has an effect that can conditionally be called anabolic. Sulfur is a necessary component of protein molecules, and protein is the basis of muscles. The intake of dietary supplements improves the effectiveness of sports training.

MSM-1000 (MSM-1000): indications and contraindications

Indications for taking MSM-1000 include:

According to experts from different countries, MSM is the best existing source of sulfur for the body, which is well absorbed by it. For this reason, dietary supplements can be safely considered an effective and safe remedy.

Contraindication to taking the supplement is intolerance to the active substance of the capsules. Rarely observed. It is worth noting that never in the entire practice of using methylsulfonylmethane in a single person has an overdose of the drug been detected.

MSM-1000 (MSM-1000): instructions for use

If the remedy is taken for the treatment of joint disorders, it can be combined with dietary supplements such as glucosamine, chondroitin.

MCM-1000 is taken 1-2 times a day. For 1 time drink 2 capsules of the drug. It is recommended to continue the course for at least 1 month.

It is not a medicine (BAA).

MSM-1000 (MSM-1000): price and sale

In order to buy MSM-1000, you just need to dial the phone number of our store or send an application through the website. Our employees will discuss with you all the necessary nuances and promptly send the parcel in the most convenient way for you. The price for MCM-1000 is indicated above. If you wish, after ordering, you can pick up your purchase yourself from our office in Moscow.

For regions, there is a free number 8 800 550-52-96.

The drug is manufactured by NOW Foods, Bloomingdale, IL 60108 U.S.A.

Delivery in Moscow and Moscow region:

P when ordering from 9500 rub. FOR FREE!

When ordering from 6500 rub. delivery in Moscow and outside the Moscow Ring Road (up to 10 km) - 150 rub.

For orders less than 6500 rub. delivery in Moscow - 250 rub.

When ordering outside the Moscow Ring Road for the amount less than 6500 rub- 450 rubles + transportation costs.

By courier in the Moscow region - the price is negotiable.

Delivery in Moscow is carried out on the day of ordering the goods.

Delivery in MO is carried out within 1-2 days.

Attention: You have the right to refuse the goods at any time before the departure of the courier. If the courier arrived at the place of delivery, you can also refuse the goods, BUT by paying for the courier's departure according to the delivery rates.

Sale and delivery of medicines is not carried out.

Delivery in Moscow is carried out only with an order amount over 500 rubles.

Delivery across Russia:

1. Express mail 1-3 days (door to door).

2. Russian Post within 7-14 days.

Payment is made by cash on delivery, or by transfer to the current account (download details).

As a rule, the cost of express delivery is slightly higher than the delivery of goods by Russian post, but you have the opportunity to receive the goods in a guaranteed short time with home delivery.

When ordering goods by cash on delivery, you pay:

1. The price of the goods ordered by you on the site.

2. Shipping cost depending on the weight and delivery address.

3. Postal commission for sending the cash on delivery amount back to the seller (by prepayment to the current account, you save 3-4% of the total purchase amount).

Important: With an order amount of up to 1500 rubles, parcels in the Russian Federation are sent only on prepayment.

Important:All orthopedic goods are sent to Russia only on prepayment.

You can check the final amount of payment for the order with our managers.

You can track the delivery of the ordered goods using a special service on the website www.post-russia.rf in the "postal tracking" section, where you will need to enter your mailing ID, which is sent to you by managers in the process of sending the goods. Also, for your convenience and minimizing the time for receiving the parcel, delivery service managers track the movement of the parcel, and on the day the parcel arrives at your post office, informs you by SMS. Having received an SMS message, you can, by presenting the identifier number, pick up your order from the post office without waiting for the mail notification of the arrival of the parcel.

Artra MSM forte: instructions for use and reviews

Artra MSM forte is a combined anti-inflammatory drug that stimulates the process of cartilage tissue regeneration.

Release form and composition

Dosage form Artra MSM forte - film-coated tablets: from dark orange to light yellow-orange, biconvex oval; the presence of a specific smell is acceptable (in a cardboard bundle 1 polyethylene bottle of 30, 60 or 100 pieces or 2-4, 6, 9 or 10 blisters of 10 or 15 pieces each).

Active substances in 1 tablet:

  • sodium hyaluronate (in terms of hyaluronic acid) - 10 mg;
  • glucosamine hydrochloride - 500 mg;
  • chondroitin sodium sulfate - 400 mg;
  • MSM (methylsulfonylmethane) - 300 mg.

Auxiliary components:

  • core: colloidal silicon dioxide - 4 mg; microcrystalline cellulose - 199.4 mg; croscarmellose sodium - 50 mg; calcium hydrophosphate dihydrate - 119.6 mg; stearic acid - 48 mg; magnesium stearate - 10 mg;
  • shell: Opadry II orange (dye sunset yellow aluminum varnish - 0.92 mg; medium chain triglycerides - 0.6 mg; hypromellose - 17.56 mg; maltodextrin - 4.68 mg; polydextrose - 7.92 mg; dye titanium dioxide - 0.44 mg; talc - 7.88 mg) - 40 mg.

Pharmacological properties

Pharmacodynamics

Artra MSM forte has an analgesic and anti-inflammatory effect. The components of the drug have the ability to inhibit the progression of osteoarthritis. Other effects include suppression of destruction and stimulation of cartilage tissue regeneration, improvement of blood flow in the subchondral bone, and a decrease in the need for non-steroidal anti-inflammatory drugs.

The main properties of the components of Artra MSM forte:

  • chondroitin sodium sulfate - takes part in the synthesis of connective tissue and is an additional substrate in the formation of a healthy cartilage matrix. Stimulates the synthesis of proteoglycans and type II collagen, the formation of hyaluronan, and also maintains the viscosity of the synovial fluid, protects hyaluronan from the damaging effects of free radicals and enzymatic cleavage (by suppressing the activity of hyaluronidase);
  • glucosamine hydrochloride - takes part in the synthesis of connective tissue; with the introduction of exogenous glucosamine, the production of cartilage matrix is ​​enhanced and non-specific protection against chemical damage to the cartilage is provided;
  • MSM is a sulfur-containing organic compound (natural sulfur content is 34%). It has an analgesic and anti-inflammatory effect. It is one of the key metabolites of dimethyl sulfoxide. It is part of many endogenous proteins (including connective tissue proteins - elastin, collagen, keratin), hormones and other metabolically active compounds;
  • hyaluronic acid - is a polysaccharide of the group of acidic glycosaminoglycans, is one of the important components of the synovial fluid and determines its viscoelastic properties. The substance forms a covering layer on the entire inner surface, which helps protect the articular cartilage and synovial membrane from mechanical damage, as well as from inflammatory factors and free radicals.

Pharmacokinetics

When taken orally, the bioavailability of glucosamine is 25% (first pass effect through the liver).

Plasma concentration of chondroitin sulfate with a single oral dose of 800 mg (or 400 mg twice a day) for 24 hours increases dramatically. The absolute bioavailability is 12%. As high-molecular and low-molecular derivatives, approximately 10 and 20% of the dose taken are absorbed, respectively.

In experimental models, when administered orally, a certain bioavailability of hyaluronic acid was noted.

Chondroitin sulfate is distributed in tissues. Its highest concentrations are found in articular cartilage, kidneys and liver. Approximately 30% of the dose taken persists for a long time in muscle and bone tissue.

Glucosamine is excreted mainly unchanged by the kidneys; partly through the intestines.

Chondroitin sulfate is metabolized by desulfurization. Excreted with urine. T 1/2 (half-life) - more than 5 hours.

Indications for use

  • osteocondritis of the spine;
  • osteoarthritis of the peripheral joints.

Contraindications

Absolute:

  • pregnancy and lactation;
  • age up to 15 years;
  • individual intolerance to the components of the drug.

Relative (Artra MSM forte is prescribed under medical supervision):

  • diabetes;
  • blood clotting disorders;
  • seafood intolerance (shellfish, shrimp);
  • bronchial asthma.

Instructions for use Artra MSM forte: method and dosage

Artra MSM forte tablets are taken orally.

The duration of the course is at least 3 months.

Side effects

Possible adverse reactions: disorders of the digestive system (in the form of epigastric pain, flatulence, diarrhea, constipation, nausea, vomiting), allergic reactions.

Overdose

There are no reports of overdose cases.

Probable main symptoms: nausea, vomiting, diarrhea, hemorrhagic rashes.

Therapy: symptomatic (gastric lavage).

special instructions

In the presence of chronic diseases, a medical consultation is required before the start of the course.

Use during pregnancy and lactation

According to the instructions, Artra MSM forte is not prescribed during pregnancy / lactation.

Application in childhood

Patients under 15 years old Artra MSM forte is not prescribed (the safety profile has not been studied).

drug interaction

Artra MSM forte is compatible with non-steroidal anti-inflammatory drugs and glucocorticosteroids.

Possible interactions:

  • semi-synthetic penicillins: reducing their effect;
  • tetracyclines: increase their absorption;
  • indirect anticoagulants, antiaggregants, fibrinolytics: strengthening their action.

Analogues

The analogues of Artra MSM forte are Teraflex M, Piascledin 300, Adgelon, Alflutop, ARTRA, Biartrin, Wantong, Chondroflex, Artiplas, Rumalaya, Rumalon, KONDRONOVA.

Terms and conditions of storage

Store in a place protected from moisture at a temperature of 10-30 °C. Keep away from children.

Shelf life - 3 years.

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