How to take Mezim Forte for various gastrointestinal disorders? Mezim - indications, instructions, contraindications Mezim 10000 instructions for use for children.

What is Mezim forte 10000 for? There are situations in life when it is difficult for our stomach to cope with its immediate duties and there is a need to help it. The digestive system, as you know, is a complex biochemical conveyor, which means that the easiest way to quickly help is medication.

Among medicines, the best helpers, of course, are enzyme preparations. Enzymes themselves, in fact, are biological catalysts (in other words, they speed up chemical reactions). In the absence of them, all the reactions that ensure good performance of the gastrointestinal tract, although they took place, were so slow that people would most likely cease to exist.

An example can be given: a piece of wood in a normal environment, without ignition, would oxidize so slowly that this piece of wood can burn out in only a couple of million years. But when there is an effect of fire - fire is the physical analogue of an enzyme - this happens in a few minutes. Now you have the opportunity to imagine how long the process of digestion would take without enzymes.…

And by the way, I really want to remind you that there would be no discrepancies: enzymes and enzymes are essentially the same thing! When there is a lack of enzymes for digestion in the human body, then one of the reactions in the digestion cycle is necessarily not carried out, which means that our body does not get enough.

And as a conclusion, we can say that enzymes for digestion are precisely those magical substances that are responsible for the efficiency and, most importantly, the speed of all biochemical work in the digestive tract. The group of enzyme drugs includes biological catalysts such as lipase, trypsin, protease, elastase, chymotrypsin, alpha-amylase. What is the composition of Mezim forte 10000?

Mezim 20000: instructions for use (official)

The components of the drug Mezim forte and their action

From the list of enzyme preparations, we should separately talk about the pancreatin group. And the most famous among them is mezim forte. Every person at least once saw or heard an advertisement about how bad it is when there is heaviness in the stomach and about the presence of a magical remedy that makes it possible to digest a whole elephant, at least.

Mezim forte is an indispensable tool that helps when the pancreas is unable to cope on its own. This is also possible if there are problems with the pancreas and if the diet is too abundant.

Mezim forte 10000 are pink tablets, they acquired the color due to their shell, one tablet contains: Pancreatin with a slight intensity of enzymes:

1. Lipases - 10000 units. Ph.Eur. Pancreatic lipase is formed in the pancreas and is also contained in the pancreatic juice, then moves to the duodénum. Lipase consists of two components - hydrophobic and hydrophilic and works exclusively on the water-fat interface. It reacts in the cavity of the small intestine - the decomposition of food fats, triglycerides, into glycerol and higher fatty acids.
2. Amylase - 7500 U.Ph.Eur. Alfa-amylase is produced in the salivary glands and pancreas. Diastasis is produced in the pancreas. This enzyme helps in the process of breaking down starch and various carbohydrates in the duodenum. Amylase is excreted by the kidneys along with urine.
3. Protease - 375 U.Eur. Proteolytic enzymes (i.e. proteases) are proteins, peptide hydrolases, enzymes of the class of hydrolases that cleave amide bonds between organic amphoteric compounds in proteins and peptides. Protease plays a very important role in the breakdown of protein foods in our stomach and in the human intestine.

Is Mezim an analogue of Pancreatin and what does the latter consist of? Indeed, it is. Pancreatin is a digestive enzyme medicine that is actually an extract from the contents of the pancreas. It consists of such enzymes - lipase, amylase, protease.

It is these enzymes that are actively involved in the decomposition of fats, carbohydrates and proteins. From time to time, a small activity of its own enzymes occurs in the stomach, pancreatin compensates for this deficiency, thereby helping to improve the process of the gastrointestinal tract.

For what diseases is Mezim forte 10000 used?

Main indications for use:

1. The inflammatory process of the mucous layer of the stomach, which leads to a violation of the functions of this organ, in a word, gastritis;
2. To improve digestion in people with healthy gastrointestinal function, if there are any excesses in the diet;
3. Chronic pancreatitis is a disease that manifests itself as regular or irregular pain and signs of endocrine and exocrine insufficiency;
4. Also, if there is a need for x-ray or ultrasound examination of the abdominal cavity.

It is best to take Mezim forte 10000 before meals, but you can do it after meals and even during meals. The effect of a drunk tablet or capsule is achieved in about thirty or forty minutes. However, there is a very important rule in the use of the drug, which must be strictly followed so that the enzyme is not destroyed.

Mezim forte is covered with a special film that does not react to acid and can dissolve only if it enters the intestines, where an alkaline environment reigns. And this means - never try to chew, crush or crush Mezim forte tablets. And yet, you need to drink the drug with a sufficient amount of liquid: you can drink water or tea or juice, but be sure to avoid alkaline drinks!

The drug during pregnancy

Is it possible or not to take Mezim forte 10000 during pregnancy? There is no single answer here. The fact is that the composition of Mezim forte is not only enzymes, but also other excipients. If we pick up Mezim forte instructions for use, we can read there: “it is not forbidden to use Mezim forte during pregnancy and lactation”

In many cases, doctors say that it is possible to use the medicine for pregnant women, but there is also an opposite point of view. So it is possible or not to use the drug - the woman herself decides.

Mezim Forte: instructions for use (official)

Summary of Reviews

What are the reviews telling us? Very often, when reading reviews about Mezim forte 10000, you can come across disputes about which is better Mezim forte or Festal? In fact, these drugs differ from each other primarily in composition. Of course, Mezim forte has the largest composition of pancreatin, so it helps much faster and is highly preferred by the population. The composition of Festal also contains bile components, so it acts a little differently and is also not suitable for everyone.

And the price for Mezim forte is more attractive. The fact that Mezim is cheaper than many of its other analogues is also not an unimportant factor in our time. By the way, we note that Mezim forte 10,000 is cheaper than Festal.

How to take Mezim forte and cases of prohibition of use

How to take Mezim forte 10000? The amount of medicine is attributed to each separately, it all depends on the health problems and the quality of the food. In the absence of other indications, usually a single dose of Mezim is 2-4 tablets per meal, it is advisable to drink 1/3 or 1/2 of a single dose before meals, and the rest with a meal. How does Mezim work with other medicines?

It is not recommended to use mezim with iron-containing medicines, as this leads to a decrease in the digestibility of the latter. Also, the joint use of antacids containing calcium carbonate and / or Magnesium hydroxide is highly discouraged. As a result, a significant weakening of the effects of pancreatin.

What are the contraindications for taking Mezim? Do not take Mezim if present:

• high sensitivity to the components of the drug;
• acute pancreatitis;
• exacerbation of chronic pancreatitis.

I would like to emphasize separately that mezim should not be considered as a remedy for all gastronomic excesses, and also that this is an excellent tool for losing weight. If you need to use this drug for a long time, you should first consult with your doctor! Since the constant use of Mezim and especially an overdose can lead to an increase in the level of uric acid in the blood, in other words, hyperuricemia.

Video: Treatment with hydrogen peroxide (Professor Neumyvakin)

The drug Mezim Forte is used to ensure better digestibility of certain types of products containing different amounts of fats, proteins and carbohydrates. Mezim is an enzymatic type of preparation, which is designed to ensure healthy digestion. The product is available in the form of tablets and is dispensed from pharmacies freely, thanks to the natural and safe composition.

Photo: Instructions for use Mezim Forte

The dosage of the agent should be selected individually (the dosage of the agent is also taken into account - 10,000 or 20,000). It depends primarily on the level of deficiency of pancreatic enzymes in the human duodenum. If Mezim Forte is used as an aid when eating a large amount of fatty, fried and difficult to digest food, doctors recommend using 1-2 tablets.

For digestive disorders, the recommended dose is 2-4 tablets. In case of urgent need, the dose is increased. It is worth increasing the number of tablets taken only under the supervision of a doctor, as stated in the instructions. Usually, an increase in the number of pills taken is due to such symptoms:

• nausea;
• indigestion;
• epigastric pain.

It is important to take into account that the daily dose of lipase cannot exceed 15-20 thousand units E.F. per 1 kg. adult body weight.

You need to take the tablets while eating. At the same time, they need to be washed down with plenty of water, without chewing and swallowing whole. The duration of treatment is determined by the doctor individually for each individual patient.

Mezim Forte for children under 12 years of age is prescribed in a daily dose that will normalize the stool. This dose should not exceed 1500 IU E.F. lipases per kilogram of body weight.

The full course of therapy can be a single dose of the drug or Mezim Forte for 2-3 days. Therapy can last for several months or even years. In the latter case, such a long course of treatment is necessary as a replacement therapy for serious pathologies or gastrectomy.

Compound

Tablets Mezim Forte

Mezim Forte is available in the form of tablets (droplets) of pink color and flat shape. Tablets have a slight smell of pancreatin. One package contains 20 or 80 tablets of the product.

The preparation contains the following active ingredients:

• pancreatin - 140 mg;
• lipase - 3500 IU;
• amylase - 4200 IU;
• proteases - 250 units.

Among the fillers are the following components:

• aerosil;
• sodium carboxymethyl starch type A;
• magnesium stearate.

The dragee shell consists of several components that form a film coating:

• hypromellose;
• talc;
• azorubine varnish;
• emulsion of simethicone 30%;
• polyacrylate dispersion 30%;
• macrogol 6000;
• titanium dioxide.

Indications

Mezim Forte is indicated for use as a therapeutic agent and prevention of diseases and dysfunction of the gastrointestinal tract during overeating. Also among the indications for use it is worth highlighting:

junk food, overeating

• pathologies of the digestive system caused by dystrophic and inflammatory processes in the tissues;
• dysfunctional disorders of the gastrointestinal tract resulting from chemotherapy, surgical interventions and characterized by stool disorder, digestion, bloating, epigastric pain;
• severe hyposecretion of pancreatic enzymes, causing functional disorders in the digestive tract;
• chronic diseases of the digestive system, including hepatitis, chronic pancreatitis, gastritis and enterocolitis;
• functional acceleration of the passage of food through the intestines;
• nutritional errors (overeating, eating incompatible foods, as well as dishes that can cause bloating, excessive gas formation and fermentation processes).

Mezim is also indicated for use before ultrasound or radiography of the abdominal organs as an auxiliary, preparatory agent.

Contraindications

bowel problems

It is unacceptable to use the drug in case of acute pancreatitis. Also, in no case should you use Mezim Forte during an exacerbation of chronic pancreatitis.

Treatment of children with Mezim without a doctor's appointment is not carried out. A visit to the doctor is necessary to determine the required dose of the drug for a particular child.

Reception is not possible with hypersensitivity to any component of the drug. If an allergic reaction to the drug is detected, the drug should be stopped immediately and consult a doctor for recommendations on symptomatic treatment of the condition.

The drug is not taken with intestinal obstruction of the obstructive type. Also a contraindication is the presence of obstructive jaundice in the patient. In case of inflammatory processes in the liver tissues, the drug can be taken only after consulting a doctor.

Side effects

The frequency of side effects from taking Mezim Forte is unknown.

From the side of the cardiovascular system, tachycardia may occur.

On the part of the immune system, hypersensitivity reactions are possible, including skin rashes, lacrimation, sneezing, bronchospasm.

From the gastrointestinal tract, a few side effects may occur, the frequency of which has also not been studied. Thus, in cystic fibrosis, patients may suffer from the formation of narrowing in the ileocecal region and in the colon. From the digestive system, allergic manifestations can also occur, including loose stools, abdominal pain, frequent diarrhea and nausea.

Photo: Abdominal pain

On the part of the skin, angioedema, urticaria, hyperemia, itching and redness may occur.

From the genitourinary system in patients with cystic fibrosis, an increased excretion of uric acid in the urine may occur. In this case, the amount of uric acid must be controlled.

Among the general disturbances, a sharp sensation of intense heat, low work capacity and weakness in the body are possible.

Use during pregnancy and lactation

The use of Mezim during pregnancy and lactation has been studied scientifically, but this did not give proper safety results. Thus, taking the drug is allowed only if the benefit from its use outweighs the risk to the fetus. It is possible to use the drug for pregnant and lactating mothers only after consulting a doctor and a thorough examination.

The use of Mezim forte with other drugs and alcohol

When using Mezim Forte simultaneously with other drugs containing pancreatin, patients may experience a deterioration in the absorption of folic acid. At the same time, patients can be recommended additional sources of obtaining this missing component.

When using Mezim Forte simultaneously with antacids, there may be a decrease or complete elimination of the therapeutic effect of Mezim. This applies to taking the drug simultaneously with those antacids that contain magnesium hydroxide or calcium carbonate in their composition.

There is no data on the incompatibility of Mezim Forte and alcohol. It should be borne in mind that the simultaneous use of strong drinks with the drug can lead to inhibition of the effects of the latter.

Overdose

In case of an overdose of the drug, patients may experience a significant increase in the side effects of the drug, including:

1. Narrowing of the ileocecal region of the intestine (typical for patients with cystic fibrosis).
2. Hyperuricemia.
3. Hyperuricosuria.

Therapy of these conditions in case of overdose is symptomatic, that is, aimed at eliminating the main signs that disturb the patient.

In case of overdose in younger patients, long-term effects may occur.

Shelf life and storage conditions

The shelf life of the drug is 3 years from the date of release of the drug. Store Mezim Forte in the original packaging. The storage location must be dark and dry. When exposed to high temperatures on the dragee (above 30 ° C), the properties of the product may be distorted.

The drug should be kept out of the reach of animals and children. In case of accidental use of a large number of pills by a child or an adult, you need to go to the hospital.

Price

What is the price?

The price of Mezim Forte in Moscow ranges from 300 rubles. The cost depends on the number of tablets in the package and the pharmacy chain where the product is purchased. In general, the price of the drug in the cities of Russia is as follows:

1. Moscow - from 83 to 298 rubles.
2. St. Petersburg - from 72 to 263 rubles.
3. Yekaterinburg - from 43 to 289 rubles.
4. Novosibirsk - from 64 to 302 rubles.
5. Nizhny Novgorod - from 59 to 273 rubles.
6. Kazan - from 49 to 295 rubles.
7. Rostov-on-Don - from 78 to 260 rubles.

The cost of the drug can be significantly lower if you purchase it in an online pharmacy. It should be borne in mind that this carries certain risks, since the tool may turn out to be a fake.

Analogues

The most common and well-known substitute for Mezim Forte is Pancreatin. Despite the fact that this drug also contains enzymes, the amount of active ingredient in Pancreatin is much less than in the original product.

The differences between Pancreatin and Mezim Forte are also in the manufacturer. Mezim is made in Germany, Pancreatin is a domestic drug. Many gastroenterologists point out that Mezim should be taken to treat digestive problems and gastrointestinal diseases. At the same time, Pancreatin is more suitable as a means of prevention.

Photo: Mezim or Pancreatin? Analogues

In addition to Pancreatin, there are a number of other means representing analogues of Mezim Forte. These drugs are also quite often used as substitutes for the original remedy.

1. Creon. This drug is manufactured in Germany. Gelatin capsules contain natural pancreatin. The cost of the drug varies 300 rubles.
2. Ermital. It is also produced in Germany and contains pancreatin as the main active ingredient. The price of the tool is 219 rubles.
3. Micrasim. This drug is produced in Russia and is a direct analogue of Mezim. The drug costs about 246 rubles.
4. Panzinorm. Strong drug made in Germany. This drug contains not only pancreatin, but also a number of additional components, including bile extract and extract of the mucous membranes of cattle. Medium the price of the drug is 171 rubles.
5. Solizim. The drug is rather weak, even in comparison with Pancreatin. The tool breaks down only fats, while ignoring proteins and carbohydrates. The price is about 1020 rubles.
6. Festal. This Indian equivalent of mezim has been used by humans for over 2 decades. The product contains not only pancreatin, but also an extract of bovine bile. The price of the drug is cheaper and fluctuates from 59 rubles.
7. Enzistal. Produced in India and is the same Festal. There are practically no differences between these drugs. The average cost of funds - 88 rubles.

Important! It should be understood that taking these drugs without the advice of a doctor is unsafe. The opinion that preparations containing enzymes are absolutely safe is erroneous.

Photo: Mezim forte 10000, reviews

Mezim is a fairly well-known drug that almost every person knows. Digestive problems are very common. And just at such a moment, Mezim comes to the rescue. It contains all the necessary enzymes that can help with the digestion of food.

Mezim: tablet release form

It should be said right away that Mezim is an enzyme preparation. The main component in it is pancreatin. Pancreatin is an enzyme that contains almost all those substances that are produced by the pancreas. It contains:

• Lipase. It is a water-soluble enzyme that is involved in the digestion of fats. The main purpose of this enzyme is the breakdown of lipids and the delivery of fatty acids to cells.
• Amylase. It is a substance that helps in the breakdown of carbohydrates. It breaks down starch into oligosaccharides. Thanks to this enzyme, you can feel a sweetish taste in your mouth if you chew potatoes or bread for a long time. This enzyme is also present in human saliva.
• Protease. This enzyme helps break down the peptide bond between amino acids.

Due to the fact that these enzymes are contained in Mezim, it perfectly helps to digest fats, carbohydrates and proteins, which play an important role in the human body. If we talk about the principle of action of the drug, then it is worth saying the following.

After the tablet has been taken, all the enzymes necessary for digestion begin to be produced. In this way, the body gets rid of the enormous stress that food stagnates in the stomach, which leads to nausea, bloating, and vomiting. Sometimes Mezim is recommended to be taken before each meal in order to restore pancreatic function.

Mezim is a very good drug, the action of which is based on helping to produce all the enzymes a person needs for a normal digestion process.

Indications for use

Mezim is prescribed for problems with the gastrointestinal tract

As mentioned above, Mezim is an enzyme preparation that has an auxiliary effect for the production of all the enzymes necessary for digestion. Mezim is usually prescribed if:

1. There is exocrine pancreatic insufficiency. In this case, those enzymes that are produced by the pancreas are not enough for the normal process of digestion. Due to such a failure, nutrients are not absorbed in the body, and as a result, a person constantly feels weak, loses weight, and also feels constant discomfort in the stomach. Among the main causes of such a problem are: malnutrition, excessive alcohol consumption, starvation, diseases of the digestive system and lack of certain vitamins.
2. There is such a disease as cystic fibrosis. This disease is associated with a gene mutation, and has another name "cystic fibrosis". It manifests itself mainly from the side of the respiratory organs. Usually, patients begin with a strong cough with a discharge of very thick sputum. Unfortunately, this disease is not curable, you can only keep a person alive by taking certain drugs.
3. There are diseases of the gastrointestinal tract, namely the small intestine, large intestine, stomach
4. Have liver or gallbladder disease
5. Have diffuse liver disease
6. A person has cirrhosis of the liver
7. There are toxic liver lesions that are caused by the abuse of alcoholic beverages
8. An operation was performed to remove the gallbladder, and as a result, the occurrence of a complication consisting in the loss of fatty acids
9. There are problems with the circulation of fatty acids, which occurred due to dysbacteriosis (violation of the composition of the intestinal microflora), biliary dyskinesia
10. There were problems with the regulation of the processes of formation and separation of bile, which occurred due to diseases such as gastritis, cholecystitis

Useful article? Share the link

In contact with

Classmates

Also, Mezim is recommended to be taken if there is a single failure in digestion. Separately, it should be said that sometimes it is necessary to take a Mezim tablet if you know that you have to eat a lot, and you are afraid that the stomach cannot cope with such a volume of food.

This usually happens when a person eats a lot of meat (mainly for kebabs and steaks), nuts that are hard to digest, especially if they were eaten late in the evening, before going to bed.

Mezim's analogue - Pancretin tablets

As for the use of Mezim during pregnancy, in this case there is no accurate data on the possible harm to the baby. That is why, taking Mezim is allowed only when the benefit to the mother outweighs the possible complications in the child.

Due to the action of the main constituent substance, pancreatin, Mezim has many positive effects, especially when it comes to helping with digestion. That is why its use is so widespread. But, despite the fact that the drug is dispensed without a doctor's prescription and is freely sold in the pharmacies of the city, it should be taken only on the recommendation of a specialist who will accurately tell you about the required dosage and duration of the course of treatment.

Dosage

It should be noted that the dosage is determined based on the individual characteristics of the organism. An example reception scheme can be written as follows:

1. If the drug is taken in order to help digest food in case of excessive consumption, then one tablet should be taken before the feast.
2. If there are obvious problems with digestion, which are manifested by pain, bad stools with undigested pieces of food, then you need to take 1 tablet before each meal
3. If digestive problems are found in a child, then in this case the dosage is prescribed only by a doctor, but usually it is one third of the tablet before meals.
4. In some cases, depending on how severely the functions of the pancreas are impaired, you can increase the number of tablets to 2 at a time.

The medicine should be taken strictly before meals. In addition, the tablet does not need to be chewed, it must be washed down with water. Of course, if you decide to crack her friend, then nothing bad will happen. That's just the taste and smell of the medicine is very specific and rather unpleasant.

Side effects

Side effects when taking Mezim are very rare. But in cases where they took place, the main manifestations were:

• Allergic reaction to some components of the drug
• Nausea
• Violation of the stool, it can be either constipation or, conversely, diarrhea
• Sometimes, if the drug was taken for a very long period of time in large doses, an increase in uric acid can be detected in the patient's blood.

Mezim is a good drug to help the pancreas and stomach to digest food. In addition, this drug is considered relatively safe and is approved for use even in children. True, despite the fact that he is released without a doctor's prescription, before you start taking it, you need to consult a specialist in order to avoid unpleasant consequences.

How Mezim helps digestion, the video will tell:

Violation of the process of digestion of food in a child or adult is a common occurrence, accompanied by various unpleasant symptoms, such as bloating, nausea, diarrhea, constipation, etc. Mezim forte tablets are an affordable drug, the use of which is aimed at filling the lack of gastric enzymes and restoring functions of the digestive tract. To quickly improve your health, you need to know how to use the medication correctly, and in what dosage.

What is Mezim forte

This medicine belongs to the group of enzyme preparations designed to improve the processes of digestion of food. Doctors recommend using Mezim for diseases associated with pancreatic insufficiency and dysfunction of the digestive tract. Release form of the drug:

• Mezim forte 10000: pink-coated tablets of a flat, cylindrical shape with beveled edges. They are made in a blister of 10 pieces, the package is packed with 20 or 50 pills;
• Mezim forte 20000: tablets coated with a smooth white or grayish shell with possible internal brown patches, have a pronounced odor. Packing in a blister - 10 pieces, available in a package of 10, 20 or 50 pieces.

The benefits and harms of Mezim

The drug is prescribed for digestive disorders, both in severe form and with minor deviations. It is important to remember that, regardless of the effectiveness of the drug, course therapy is carried out only with the permission of the doctor. Subject to all the rules, the drug has a beneficial effect on the body. Supporting the work of the pancreas, Mezim forte helps to normalize the process of digestion of carbohydrates, proteins and fats, increase the absorption of valuable substances in the small intestine, relieve the feeling of heaviness when overeating.

Self-medication, accompanied by an uncontrolled number of tablets, can cause significant harm to patients if Mezim is taken in the presence of contraindications. Possessing a powerful effect, in case of an overdose, the drug increases the severity of symptoms, leads to poisoning. There are conditions in which drinking pills is strictly prohibited. These include, for example, acute pancreatitis, intolerance to components.

Compound

If the doctor prescribed Mezim, the composition of the tablet will help you find out what this drug is, what is its principle of work. The medicine contains active and auxiliary elements. The main active ingredient is pancreatin - a polyenzymatic component designed to compensate for the insufficiency of exocrine secretory function. Pancreatin enzymes act as additional ingredients:

• lipase;
• amylase;
• protease;
• trypsin;
• chymotrypsin.

The drug Mezim 10000 differs from Mezim 20000 in that the latter includes twice as many active ingredients that can quickly and effectively cope with the symptoms. Mezim 10000 is relevant for the treatment of diseases associated with the function of the gastrointestinal tract, it is used for intestinal infections, stool disorders, and also as an emergency remedy to help digest fatty foods. Mezim 20000 is indicated for chronic pancreatitis and other diseases of the stomach that have passed into the chronic stage.

pharmachologic effect

Pancreatin is obtained by extracting the porcine pancreas. This substance helps to digest proteins, fats, carbohydrates. In this case, the absorption of the digestive enzymes themselves does not occur - they are excreted naturally through the intestines. After taking Mezim forte, the process of absorption of trace elements improves, which allows you to increase important indicators of blood composition. Amylase is effective in the treatment of cystic fibrosis. The enteric coating protects enzymes from the effects of gastric juice, providing lipolytic activity of the drug.

What helps

Mezim forte is a good tool that helps the body cope with heavy food during its use. The drug compensates for the lack of enzymes, facilitates the absorption of food, prevents the development of complications due to malnutrition. The main indications for the use of the drug are:

• chronic pancreatitis;
• inflammation in the gallbladder, liver and stomach;
• cystic fibrosis;
• secretory pancreatic insufficiency;
• intestinal infectious diseases;
• flatulence;
• violation of the process of digestion of food;
• stool problems (diarrhea, constipation).

How long does Mezim work

The maximum effect of therapy after the use of the drug is observed after half an hour. According to patients, Mezim forte has excellent tolerance, quickly eliminates discomfort, and relieves abdominal pain. Patients using the medication noticed an improvement in well-being after 10 minutes. After a short time, bloating, heaviness disappears, discomfort stops.

Instructions for use Mezim forte

The drug is dispensed without a prescription, but with prolonged use, the dose is determined by the doctor individually. Before taking Mezim, it is recommended to carefully read the annotation. The treatment regimen depends on the type and severity of the disease, the number of symptoms. Standard therapy involves:

1. adults 1-2 tablets 1-3 times a day;
2. children aged 12-18 no more than 20,000 IU of lipase per 1 kg of body weight;
3. a child under 12 years old - up to 1500 IU per 1 kg of weight.

Tablets are taken orally before meals or during a meal. The medicine is drunk whole, without chewing, accompanied by a large volume of water, so as not to destroy the acid-resistant top layer. The treatment course can last from 1 day to several months. If, when diagnosing digestive pathologies, the specialist prescribed replacement therapy with Mezim, the method of application provides for its constant use according to the doses indicated by the doctor.

Instructions for use for children

Mezim is prescribed to a child as a supportive agent in case of disruption of the digestive tract. A single dose of the drug helps to eliminate the consequences of accidental overeating, poisoning or errors in the diet. It is effective for the treatment of children suffering from pancreatitis, diseases of the biliary tract and duodenum. Capsules are prescribed to children according to the following scheme:

1. 1-7 years - ¼ -1 dragee no more than 3 times a day;
2. 7-12 years - 1-2 tablets up to 3 times a day;
3. 12-18 years - up to 20,000 IU of lipase per 1 kg of weight.

The duration of therapy depends on the state of health and ranges from 4 to 30 days. To avoid a decrease in the medicinal effect, it is better to swallow the capsule whole with a sufficient amount of liquid. Small children can be given the product crushed in water using a plastic syringe. It is not recommended to use enzymes for newborns and babies under 1 year old.

During pregnancy and lactation

Developed for the Mezim preparation, the instructions for use allow the medication to be taken during pregnancy. However, doctors advise resorting to treatment only in extreme cases, when the benefit to the mother is higher than the possible risks to the fetus. If side effects occur, the use of enzymes should be discontinued immediately. During breastfeeding, drinking enzymes is not prohibited.

drug interaction

With the simultaneous use of the drug with iron-containing medicines, the level of absorption of iron into the blood decreases. Indicators of poor digestibility of this microelement are: weakness, dizziness, development of anemia. Taking Mezim together with antacids, including magnesium and calcium, is possible when using high doses of the drug, since the effectiveness of the enzyme ingredients is significantly reduced.

Side effects

Mezim is well tolerated by the body and is practically devoid of negative aspects. To eliminate the consequences, a diet and refusal of the medication are prescribed. Side effects are observed with prolonged use of the drug or overdose. Among them are noted:

• nausea;
• aching pains affecting the entire abdominal cavity;
• allergy;
• malfunction of the intestines;
• increase in the concentration of uric acid;
• hyperuricemia.

Contraindications

The use of enzymes is not recommended if there is a high sensitivity to at least one of the components that make up the drug. Do not use Mezim in the presence of intolerance to enzymes of animal origin. A contraindication to taking the drug is an exacerbation of pancreatitis and chronic pancreatitis in an acute form.

Analogues

There is a wide range of enzyme supplements on the pharmaceutical market. They are similar in composition, differing only in the amount of amylase and excipients. Medicines of this group are intended to restore the digestive processes, maintain the function of the gastrointestinal tract of people who lead an inactive lifestyle, so they should always be in the first-aid kit. The main analogues of Mezim include:

• Pancreatin;
• Festal forte;
• Creon 10000;
• Gastenorm forte;
• Enzistal;
• Panzinorm;
• Vestal.

Price

The drug is an affordable tool, effective in the treatment of diseases of the stomach and pancreas. The price of tablets depends on the form of release, the manufacturer.

Release form Mezima

Video

Digestive problems are familiar to almost everyone. Unpleasant sensations in the abdomen are most often observed after eating. The lack of enzymes necessary for the digestion process can be compensated by special medications. Instructions for use "Mezim forte 10000" recommends using the medicine for violations of the digestive system.

What is a remedy?

The stomach does not always cope with its direct duties. The role of the main assistants in this case is played by medicines, which contain enzymes - biological catalysts that speed up chemical reactions in the body. The most popular enzyme preparation is Mezim forte 10000 manufactured by the German pharmaceutical company Berlin-Chemie. The main effect of the drug is aimed at normalizing the process of digestion of food and the absorption of nutrients.

With a lack of digestive enzymes, over time, the development of diseases of the liver, pancreas, and gallbladder is observed. After establishing the cause of the pathological condition, the specialist may prescribe the drug "Mezim forte". The enzymes contained in the product contribute to the absorption of fats, proteins and carbohydrates necessary for the full functioning of all organs and systems. Depending on the patient's condition, a certain dosage of active substances is selected ("Mezim forte 10000" and "Mezim forte").

What helps?

The drug has an auxiliary effect and contributes to the production of the amount of enzymes necessary for the digestion of food by the pancreas. According to the official instructions, "Mezim forte" is taken according to the following indications:

• Violation of the function of the (external) pancreas. This can be caused by diseases such as cystic fibrosis (damage to the external secretion glands), chronic pancreatitis.
• Inflammatory processes in the gastrointestinal tract (acute and chronic form).
• Digestive disorders caused by surgery (gastric resection), irradiation of the digestive tract, kidneys, liver, gallbladder.
• Infectious lesion of the intestine, which provoked prolonged diarrhea.
• Eating disorders (overeating, eating unfamiliar and hard to digest food).
• Chronic pathologies of the liver.
• Preparation before examination of the stomach, intestines (endoscopy, X-ray, ultrasound).

The composition of the drug

The main component of the product is pancreatin - a substance in the form of a powder made from the pancreas of porcine glands. The minimum lipatic activity of pancreatin is 3500 IU. Instructions for use "Mezim forte 10000" indicates that this enzyme contains substances necessary for normal digestion:

1. Lipase - refers to water-soluble enzymes and is an integral component of pancreatic juice. Promotes the absorption of fats. One tablet contains 10,000 units.
2. Protease - is responsible for the normalization of microflora in the digestive tract. The action of the substance is aimed at good digestion of proteins and cleavage of the peptide bond between amino acids. One tablet contains 375 IU.
3. Amylase - necessary for the proper breakdown and absorption of carbohydrates. This enzyme was first discovered by scientists. Produced by the salivary and pancreas. One tablet contains 7500 IU.

Mode of application

It is necessary to understand that it is possible to get rid of digestive problems only by determining the true cause of the pathological condition. In case of violation of external digestion, doctors most often recommend taking "Mezim forte". What does the drug help? First of all, it will improve the digestion of food and relieve unpleasant discomfort and heaviness after eating.

Tablets should be taken with meals or immediately after a meal. Chewing the medicine is prohibited! Tablets should be washed down with a large amount of alkaline liquid - mineral water, juice.

Dosage

Before taking Mezim Forte, you should get expert advice on the optimal dosage, which is calculated based on the patient's condition. If the enzyme preparation must be taken constantly, as a replacement therapy, only the attending physician can adjust the daily dose.

Usually a single dose is 2-4 tablets per meal. Depending on the type of product and the amount of active substances in the composition, the dosage may vary. To eliminate temporary problems with digestion caused by errors in the diet, a minimum dose of substances in the composition of Mezim Forte is prescribed. The price of the drug also depends on the dosage and the number of tablets in the package. The minimum cost of the drug is about 75 rubles. (20 tablets).

Is an enzyme preparation given to children?

In pediatric practice, there are often cases when substitution therapy is indispensable. The enzyme preparation "Mezim forte" for children is prescribed if it is necessary to establish and improve the digestive process. Pancreatic enzymes in the composition of the tablets help to cope with increased gas formation, eliminate discomfort after eating. Also, the drug is prescribed after surgery, with intestinal infections, diarrhea.

According to the instructions, the enzymatic agent is contraindicated for use in children under 3 years of age. The daily dose should not exceed 1500 IU per 1 kg of the child's weight. Usually, before eating, you should give the baby a third of the tablet.

For children from 12 years of age, the dose may increase to 15,000 IU. Doctors recommend that you do not use the medicine for the treatment of children on your own and first consult a pediatrician.

Causes of Enzyme Deficiency

With the right diet, the use of healthy foods, the body is able to independently produce the required amount of enzymes. The lack of these substances can develop against the background of the following factors:

• Constant overeating.
• Eating insufficiently processed food.
• The presence of inflammatory processes in the digestive organs.
• Problems with metabolism.
• Poor chewing of food.
• Eating foods high in fat, protein and carbohydrates.

Also, deterioration of the condition is observed with intestinal dysbacteriosis, congenital diseases of the digestive tract. To eliminate the problem associated with enzyme deficiency, the drug "Mezim forte" will help. The dosage may vary depending on the diagnosis. The maximum daily dose is not more than 20,000 IU per day.

Contraindications for use

Enzyme drug "Mezim forte" has a number of contraindications regarding treatment with this drug:

• Pancreatitis in the acute phase or exacerbation of the chronic form.
• Hypersensitivity to the components in the composition of the tablets.
• Intolerance to active substances.
• Age up to 3 years.
• Lactose intolerance.
• Syndrome of glucose-galactose maldsorption.

During pregnancy and lactation, an enzyme agent can be prescribed to improve digestion. Instructions for use "Mezim forte 10000" says that there are no data on the use of the drug for this category of patients. At the same time, doctors often prescribe the drug for women in a position where periodically there is a feeling of overeating, heaviness in the epigastric region. The drug should be used with caution and only in emergency cases. You should first consult with your gynecologist.

Side effects

The development of side effects caused by taking an enzyme preparation is extremely rare. Some negative reactions can develop only in case of long-term drug therapy, allergies to components or exceeding the recommended daily dose.

Side effects are expressed in the form of rashes, itching, nausea, indigestion (constipation, diarrhea). An increase in the values ​​of uric acid in the blood is observed during long-term treatment with Mezim Forte.

Price and reviews

The cost of the drug depends on the number of tablets in the package and dosage. You can buy "Mezim forte" at a pharmacy kiosk for 75-90 rubles. (pack of 20 tablets). "Mezim forte 10000" will cost the patient 200-250 rubles. (20 tablets).

Instructions for use "Mezim forte 10000" positions the tool as the most effective and safe of this category of pharmaceutical products. Numerous positive recommendations from patients confirm the presence of a pronounced therapeutic effect and improvement in the condition as early as 20 minutes after taking the tablets. Subject to the dosage and recommendations for treatment, the drug does not cause side effects and is well tolerated by the body.

It is the composition of Mezim that determines its high therapeutic efficacy. The drug belongs to the group of enzyme preparations that are used to restore the functional activity of the gastrointestinal tract. Mezim improves digestion, promotes proper absorption of nutrients and biologically active substances. But do not forget that the tablets are not intended for continuous use. Like all pharmacological preparations, Mezim has contraindications for use. Therefore, before using the drug, you should consult a gastroenterologist, and if necessary, undergo a complete examination of the digestive tract.

Enzymes that are part of the drug Mezim improve the functioning of the digestive gland

The composition of the drug and the release form

Thanks to the active substance Mezim pancreatin, it is used in the treatment of stomach diseases for the breakdown of proteins, fats and carbohydrates during the digestion of food. After taking the pills, dyspeptic disorders disappear - nausea, bloating, heartburn and belching. To give the drug maximum therapeutic efficacy, the developers supplied Mezim with special auxiliary ingredients.

Active ingredient and auxiliary ingredients

Manufacturers produce Mezim in the form of coated tablets. It is necessary to protect the active substance of the drug from the aggressive hydrochloric acid produced by the glandular cells in the stomach. The presence of the shell allows pancreatin to freely penetrate into the small intestine, where its therapeutic activity is manifested. Without such protection, most of the active substance would be destroyed directly in the stomach. For the formation of tablets and their protective shell, organic and inorganic compounds are used:

• milk sugar;
• simethicone;
• polyethylene glycol 6000;
• titanium dioxide;
• sodium hydroxide;
• magnesium stearate;
• silica;
• hypromellose;
• polysorbate 80.

The characteristic pink color of Mezim forte and Mezim 10000 tablets is given by the coloring matter azorubine. This compound is absent in Mezim 20000, so the shell of the dosage form is white, and when broken, small blotches of a darker color are noticeable. Tablets have a specific smell, which gives them the active substance.

Varieties of the drug

Depending on the stage of the course and the type of gastric pathology, patients may be assigned one of the following types of Mezim:

• Mezim forte 100 mg No. 20 and No. 80;
• Mezim 10000 125 mg No. 20 and No. 50;
• Mezim 20000 250 mg No. 10, No. 20, No. 50.

The amount of active ingredient in Mezim tablets can vary only slightly. A preparation with a small amount of pancreatin is usually used for mild digestive disorders. Mezim 20000 is intended for patients whose pancreas produces few enzyme compounds.

The primary packaging of all forms of Mezim is blisters made of metallized foil with contour cells. This is necessary to protect the drug from exposure to:

• temperature;
• direct sunlight.

The fact is that all digestive enzymes are not stable, they can decompose under the influence of adverse factors. The secondary packaging of Mezim is a cardboard box with an enclosed detailed annotation. In connection with the increasing cases of counterfeits of this drug, manufacturers have provided each pack of tablets with a hologram. When removing the top protective layer, a stylized letter "M" is revealed.

The unique composition of Mezim will help travelers cope with unusual foods

The effect of the drug on the human body

The enzymes that make up Mezim are vital for the proper functioning of not only the gastrointestinal tract, but the entire human body. Various types of enzymes are responsible for the breakdown and processing of nutrients, as well as their absorption. Each enzyme is unique, designed to perform only a specific task. The combined composition of Mezim contains several groups of enzymes, so the drug is used in the treatment of numerous pathologies.

Pancreatin is a complex of enzymes that the human pancreas produces in a normal state of health. The main biologically active substances include:

• Lipase. The enzyme is highly soluble in water, has an effect on esters, stimulating the processes of their catalysis. Lipase is directly involved in the breakdown and digestion of neutral lipids, as well as their dissolution and fractionation. The enzyme is active under the action of bile, dissolving fats, fatty acids, fat-soluble vitamins;
• Amylase. The biologically active compound is involved in the metabolism of complex and simple carbohydrates. The main part of amylase is produced by the pancreas, and a small amount is produced by the salivary glands. After the breakdown of carbohydrates by the enzyme, oligosaccharides are formed, which are completely absorbed in the human body;
• Protease. This is the largest group of enzymes that are involved in protein metabolism. They break down proteins into free amino acids by breaking peptide bonds. In the gastrointestinal tract, these compounds are in inactive forms - proenzymes and zymogens. But under the influence of the pH of the medium or enzymes of another type of protease, they are activated.

Mezim acts as a stimulant for the secretion of its own enzymes by the pancreas, stomach, and small intestine. Under the influence of pancreatin, bile secretion improves and the functional activity of the digestive organs is restored, which allows even very fatty, heavy foods to be fully absorbed. Mezim shows therapeutic properties only in the alkaline environment of the intestine 30-40 minutes after taking the tablets.

The active substance of the drug is not adsorbed by the mucous membranes of the gastrointestinal tract. Digestive juices and beneficial bacteria break down and denature pancreatin. Mezim is excreted from the human body with each bowel movement.

The enzymes that make up Mezim will help to avoid indigestion after heavy feasts

Pros and cons of the drug

Like all pharmacological preparations, Mezim can exhibit side effects that are harmful to the human body. As a rule, negative symptoms appear when patients do not comply with medical recommendations - exceeding daily and single dosages, as well as the duration of taking pills. But it is difficult to overestimate the positive properties of the drug used in the treatment of various diseases. The benefits and harms of Mezim are directly dependent on the rationality of his intake.

Benefit

The main purpose of Mezim is the normalization of the activity of the pancreas for the production of digestive enzymes. Therefore, gastroenterologists recommend a course of Mezim when diagnosing the following diseases in a person:

• cystic fibrosis;
• pathologies of the gastrointestinal tract, accompanied by insufficient production of enzymes by the pancreas;
• deficiency of enzymes after operations on the intestines or stomach;
• motility disorders of the gastrointestinal tract;
• increased gas production.

Mezim is indicated for admission to patients in preparation for surgery or endoscopic examination.

Warning: “If a person eats unbalanced, often passes or likes to snack on the run, then sooner or later a failure occurs in the body. All vital systems begin to experience an acute shortage of nutrients and biologically active substances, which negatively affects the well-being and appearance of a woman or a man.

Harm

With improper use of Mezim, its side effects are manifested - peristalsis disorder, nausea and vomiting. Irrational use of the drug is facilitated by intrusive television advertising, suggesting the use of a drug to improve digestion. With the constant intake of Mezim, the pancreas reduces the production of its own enzymes. Therefore, after the abolition of tablets, a person has serious problems with the digestion of food.

Some people use Mezim for constipation. The drug has nothing to do with laxatives, so it is not used for quick bowel movements. Such an effect can occur only in one case - if a person takes an excessive amount of tablets, which provokes a side effect of the drug - diarrhea. Gastroenterologists warn about the inadmissibility of self-medication with Mezim, which will cause serious harm to the human body.

Enzyme preparation

Active substance

Release form, composition and packaging

◊ Coated tablets pink, flat-cylindrical, with almost plane-parallel surfaces and beveled edges, with a characteristic smell of pancreatin.

Excipients: microcrystalline cellulose, sodium carboxymethyl starch (type A), colloidal silicon dioxide, magnesium stearate.

Shell composition: talc, hypromellose, azorubine varnish (E122), simethicone emulsion 30% (dry weight), polyacrylate dispersion 30% (dry weight), titanium dioxide (E171), macrogol 6000.

20 pcs. - blisters (1) - packs of cardboard.
20 pcs. - blisters (2) - packs of cardboard.
20 pcs. - blisters (4) - packs of cardboard.
20 pcs. - blisters (5) - packs of cardboard.

pharmachologic effect

The drug compensates for the insufficiency of the exocrine function of the pancreas.

The enzymes lipase, amylase and protease that are part of pancreatin facilitate the digestion of fats, carbohydrates and proteins, which contributes to their more complete absorption in the small intestine.

Indications

- insufficiency of the exocrine function of the pancreas, (chronic, cystic fibrosis);

- chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gallbladder. Conditions after resection or irradiation of these organs, accompanied by disorders of food digestion, diarrhea (as part of combination therapy);

- to improve the digestion of food in patients with normal gastrointestinal function in case of nutritional errors;

- preparation for X-ray and ultrasound examination of the abdominal organs.

Contraindications

- hypersensitivity to the components of the drug;

- acute pancreatitis;

- exacerbation of chronic pancreatitis.

Dosage

The dose is determined individually depending on the degree of indigestion.

Adults: 1-2 tab. before meals, without chewing and drinking water. If necessary, take another 1-4 tablets during meals.

At children the drug is used as prescribed by the doctor.

The duration of treatment can vary from a few days (if the digestive process is disturbed due to errors in the diet) to several months or years (if you need constant replacement therapy).

Side effects

In isolated cases, in patients suffering from cystic fibrosis, the formation of strictures in the ileocecal region is observed after taking high doses.

drug interaction

With the simultaneous use of pancreatin with iron preparations, a decrease in the absorption of the latter is possible.

The simultaneous use of antacids containing calcium carbonate and / or magnesium hydroxide can lead to a decrease in the effectiveness of pancreatin.

Mezim is a drug of the enzyme group, the main function of which is the replacement of protease and lipase in the pancreas. Mezim will help to strengthen the efficiency of digestion, to balance the work of the organs of the intestinal tract.

Composition release form

Mezim forte 20000 includes the following components:

• Pancreatin.
• Lipase-3500 units.
• Amylase-4200 units.
• Proteases - 250 units.

Additional items:

• Cellulose.
• Silica.
• Sodium carboxymethyl starch.
• magnesium stearate.

The shell of the drug includes:

• emulsion of simethicone.
• Talc.
• Azorubine varnish.
• Titanium dioxide.
• Macrogol 6000.

Mezim Forte 10000 consists of the following substances:

• Pancreatin-137.5 milligrams.
• Lipase-10000 units.
• Amylase-7500 units.
• Proteases - 375 units.

Mezim is offered in the form of tablets with a special shell (resistant to the acidity of gastric juice). Due to this, the tablets do not immediately dissolve under the influence of hydrochloric acid.

The drug easily penetrates into the intestinal cavity, promotes the natural process of splitting proteins, fats and carbohydrates in the body.

Pharmacological properties

1. Mezim Forte acts on the body as a pancreatic protector due to natural pancreatin. It is specially isolated from the pancreas of CRH, Household.
2. Lipase and amylase helps to normalize the functions of the pancreas, helps to eliminate endocrine disorders.
3. After dissolution of the shell, the active components of the drug are released and begin to act in the cavity of the duodenum.
4. Enzymes are absorbed in the digestive tract and act in the intestinal lumen.

For children and adults, Mezim Forte is prescribed as an additional therapy to improve the functioning of the gastrointestinal tract.

Before taking the drug, it is necessary to find out the exact cause of problems with the work of the intestines, any medication should be performed only by the attending physician.

Instructions for use "Mezim Forte 10000"

Mezim Forte 1000 helps with the following disorders:

Dosage:

• If there are no additional doctor's prescriptions, take 1-2 tablets for indigestible food and related problems.
• With pathological processes, ulcers, colitis, obstruction 3-4 tablets at a time. If necessary, the dose can be increased, after consulting with a gastroenterologist.
• In this case, the daily dose of lipase in the composition of the drug should not be more than 15000–20000 OD.E.F. per kg of body weight.

Take mezim during meals, do not chew, do not put under the tongue, swallow whole with a glass of warm water.

Method of application of the drug "Mezim 20000"

The use of the drug is prescribed in each case separately by the attending physician, it helps in the following cases:

Swallow the medicine whole, drink plenty of water. Do not exceed the dose, the daily norm of lipase should not exceed 15,000–20,000 OD.E.F. per 1 kg of body weight. Continue therapy on the recommendation of a doctor, from 3-5 days to several years for complex diseases.

Contraindications to the use of Mezim

With the following phenomena, it is strictly forbidden to use Mezim Forte:

• Acute pancreatitis.
• Complicated course of chronic pancreatitis.
• Hypersensitivity to active components.
• Children under 3 years old.
• Galactose intolerance.
• Lactase deficiency.
• Syndrome of glucose-galactose adsorption.

Side effects of Mezim

Despite the high efficiency and safety in case of improper use, neglect of precautions, side effects appear:

• Allergy.
• Changes in the consistency of feces.
• Pain and tightness in the epigastric region.

Long-term use of Mezim Forte can cause the following phenomena:

• An increase in the level of urea in the urine (hyperuricoseria).
• Increased levels of blood and acid in the urine (hyperuricemia).
• In the treatment of cystic fibrosis, the patient often shows symptoms of narrowing of the lumen of the intestinal area.

Use in children

Starting from the age of 3, it helps children in the treatment of digestive diseases and is prescribed in a standard dose - 1-2 tablets during a meal. Children under 12 years of age are prescribed a maximum dose of lipase no more than 15,000 OD.E.F. per day.

Use during pregnancy and lactation

To date, there have not been enough studies showing the effect of Mezim Forte on a pregnant woman and fetus. But doctors do not recommend taking risks and using the drug.

During pregnancy and lactation, the use of an enzyme agent can be carried out only after consulting a doctor and in extreme situations.

Mezim cost

The drug Mezim Forte is offered in pharmacies without a doctor's prescription. The average cost of an enzyme agent is from 100 to 300 rubles , depending on the package configuration and composition.

Analogues

If it is impossible to take Mezim, analogue enzyme medicines have been developed today.

Festal

Enzyme agent "Festal" has a similar composition, the drug is developed on the basis of pancreatin.

Indications for use:

Shows the use of 2 tablets 3 times a day before or after meals.

Contraindications:

• Hepatitis.
• Jaundice.

Penzital

The composition of the enzyme medicine includes pancreatin, lactose, titanium dioxide, povidone, MCC and many auxiliary elements. Due to this, the drug can completely replace the missing secret of the pancreas, to normalize the process of digestion of food.

Indications for use:

The dosage is prescribed 1-2 tablets 3 times a day, children are prescribed to take 1 tablet 2 times a day.

Contraindications:

• Acute pancreatitis.
• Severe form of chronic pancreatitis.
• Allergy to one of the components.

Side effects:

Creon

The enzyme product is developed on the basis of pancreatin, additionally it contains macrogol 4000, dimethicone 1000, hypromelase phthalate, gelatin, iron oxide, etc.

Indications for use:

• Therapy of pancreatic secretion insufficiency.
• Helps with constipation of various etiologies.
• Cystic fibrosis.
• Pancreectomy.
• Helps after gastrectomy.
• Shwachman-Diamond syndrome.

Contraindications include patient intolerance to one of the components that make up the enzymatic agent.

metoclopramide

The composition of "Metoclopramide" includes the main substance - metoclopramide hydrochloride, additionally included:

• Potato starch.
• calcium stearate.
• Povidone.
• lactose monohydrate.

Indications for use:

Adults drink 10-20 mg per 10 kg of body weight, children - 10 mg per 10 kg of body weight. It is necessary to take the drug 3 times a day. Take the tablets 30 minutes before a meal, swallow immediately and drink plenty of water.

Contraindications:

• Hypersensitivity to components.
• Bleeding in the stomach.
• Intestinal obstruction.
• Perforation of the stomach.
• Epilepsy.
• Extramyramidal dysfunction.
• Tumors and neoplasms.
• Pregnancy.
• Children up to 12 years old.

Motilium

The composition includes: Domperdon, corn starch, potato cellulose, magnesium stearate, lactose, vegetable oil, hydromellose, polyvodone.

Indications for use:

• Gastrointestinal reflux.
• Helps with nausea, vomiting.
• Intestinal problems associated with Parkinson's disease.
• regurgitation syndrome.
• Changes in gastric motility in children.

The method of application depends on the specific disease, it is prescribed only by a doctor after a complete examination.

Contraindications:

• Perforation of the walls of the stomach, intestines.
• Tumor of the pituitary gland.
• Prolactinoma.
• Bleeding in the stomach.
• Allergy to domperidone.

Side effects:

• Gynecomastia.
• Amenorrhea.
• epigastric disorders.
• Allergy in the form of a rash, itching.

Which is better: "Festal" or "Mezim"?

Both drugs are enzyme agents used as adjunctive therapy. Despite their effectiveness and safety, a healthy person cannot use them. They have their own contraindications and side effects.

Indications for use of Festal and Mezim

Both medicines are prescribed for violations of the secretory system, pancreas, and are also prescribed for chronic diseases of a dystrophic nature, inflammatory processes.

Festal and Mezim are prescribed after partial or complete removal of the intestines, other organs of the digestive system to help in the digestion of food.

How are the drugs different?

Before taking this or that drug, you need to know what exactly the difference between drugs is.

Festal	Mezim
The difference is that in addition to the main component (pancreatin), the composition of Festal also includes hymecellulase, bovine bile. Therefore, "Festal" acts much faster and the intestinal walls are more actively absorbed, normalizing its work. Therefore, many people choose Festal, in comparison with Mezim.	Many doctors consider both remedies to be quite effective, depending on the individual characteristics of the patient's body, the specialist makes an appointment.
The cost of both medicines is not particularly different, "Mezim" is offered in pharmacies for 20–40 rubles cheaper.

Any drugs that improve fermentation, such as Mezim, Festal, are strictly forbidden to drink along with anti-anemia drugs. The combination of these drugs limits the ability of iron to be absorbed into the blood.

"Mezim" or "Creon" - which is better?

Medicines "Mezim" and "Creon" both belong to the enzyme group and are prescribed by doctors for violations of the digestive system, the normal functioning of the pancreas.

Similarity of drugs

Both medicines "Mezim" and "Creon" are analogues, according to the composition of the basic active components, they are completely similar (pancreatin, amylase, lipase, protease).

As additional components, the drug "Mezim" includes sodium carboxymethyl starch, magnesium stearate.

Enzyme tablets "Creon" additionally include liquid paraffin, methylhydroxypropylcellulose phthalate, dimethicone, polyethylene glycol.

Both drugs, getting into the body:

• Break down into fatty acids.
• Helps improve carbohydrate digestion.
• Break down proteins into amino acids.

Choosing the most powerful of the two drugs, you can give your preference to Creon 25000 tablets, which has more pancreatin content.

Also, both enzyme preparations have similar contraindications:

• Acute diseases of the pancreas.
• Exacerbations of pancreatitis.
• Allergic reactions to the components of the composition.

Drug differences

Mezim	Creon
Experts recommend using Mezim for general disorders of the digestive system, to facilitate the digestion of spicy, fried and heavy foods.	Then, as the enzyme preparation "Creon" is prescribed as a replacement therapy for violations of the patency of the bile ducts, chronic pancreatitis. The drug acts in a targeted manner, due to the high concentration of the active ingredient.
Tablets "Mezim" are prescribed one-time.	The drug "Creon" can be prescribed a course of therapy from 2-3 weeks to several years.
The mechanism of action of drugs differs based on the dosage and direction of action.
Mezim tablets are mixed with food for a long time and unevenly, they do not immediately reach the intestinal cavity.	Enzyme agent "Creon" is offered in the form of capsules with a special shell, in which microspheres are located. Thanks to this solution, when they enter the stomach, they release active substances, but are not destroyed. After a therapeutic effect, the shells are broken down into proteins, carbohydrates.
	Due to the fact that "Creon" is offered in the form of microspheres, they are mixed with products and split in gastric juice.

To select a specific enzyme agent, it is necessary to be based on the disease and characteristics of the patient. Be sure to consult with a specialist before taking.