Kagocel side effects in children. Kagocel - instructions for use in adults and children, dosage, analogues of antiviral medicine

Kagocel refers to antimicrobial agents for systemic use, namely antiviral drugs. The name of the pharmacological group in which Kagocel belongs includes immunomodulators, so the medicine has two directions of action.

The drug is capable of providing antiviral, antimicrobial, immunomodulatory effects, stimulating the production of interferon, which is the main nonspecific immune factor.

In addition, the drug stimulates the synthesis of alpha, beta and gamma interferons, the action of which is aimed at inhibiting the production of RNA and viral proteins. In addition, direct and indirect activity of interferons against tumor cells is observed.

The therapeutic effect after the first dose of Kagocel is noted within 4 hours, after which the high level of interferons is maintained for up to 4-5 days. The medicine does not have a toxic effect on the body and does not accumulate in tissues, provided that the recommended dosages are followed.

Kagocel is a powerful drug with an antiviral effect, stimulates the production of interferons and activation of the immune system. In addition, the medicine is considered an immunomodulator, which also has a detrimental effect on the course of the disease.

ATC

J05AX Other antivirals

Active ingredients

Pharmacological group

Antiviral agents

pharmachologic effect

Immunomodulatory drugs

Antiviral drugs

Indications for use Kagocel

Based on the main therapeutic properties of the drug, it is possible to identify diseases for which the drug will be most effective.

Thus, the indications for use of Kagocel imply its use in adults to prevent infection and treat pathologies of a viral nature. Most often, the medication is used for influenza infections and other respiratory pathologies of viral origin.

In childhood (from 3 to 6 years), Kagocel can be used only for therapeutic purposes for viral diseases. In particular, the drug is effective for ARVI with manifestations of rhinitis or nasopharyngitis.

As for older children (from 6 years old), Kagocel can be used not only for therapeutic purposes, but also for preventive purposes. It is especially important to use the medicine in winter, when the child’s body is weakened and susceptible to frequent viral attacks, as well as when a flu epidemic is approaching.

Indications for use of Kagocel also include the treatment of herpes infection in adults with its frequent clinical manifestations in the form of rashes and general symptoms (fever, weakness, headache and aching joints). In addition, the drug is effective in case of co-infection in the presence of respiratory disease and activity of the herpes pathogen.

As an auxiliary drug, Kagocel is used in the treatment of urogenital chlamydia.

Release form

The main active component of the drug is Kagocel. Among the auxiliary components, it is worth highlighting potato starch, calcium stearate, Ludipres (lactose monohydrate, crospovidone, povidone).

The release form of Kagocel is presented as a tablet preparation. Each tablet contains 12 mg of kagocel, which allows you to strictly adhere to the dosage and avoid the occurrence of adverse reactions and overdose.

The main physicochemical properties of the drug are its round shape, convex surface on both sides, and color - from light cream to brown with small inclusions.

This form of release does not allow the drug to be used in children under 3 years of age, however, each tablet contains a certain amount of the active substance, which ensures that the medication can be taken without dividing the tablet into parts.

The tablet form of the drug is convenient to use, as it is strictly dosed and does not cause a large number of adverse reactions.

Pharmacodynamics

Kagocel is an antiviral drug, which determines its mechanism of action. The medicine is a stimulator of interferon production.

Pharmacodynamics Kagocel ensures the production of late interferon, represented by a combination of alpha and beta interferons, which are characterized by a powerful antiviral effect. Kagocel stimulates its production in all cells responsible for the immune response. Among them, the most active are lymphocytes (T- and B-), granulocytes, endothelial and macrophage cells, as well as fibroblasts.

After a single dose of the drug, the interferon titer increases to a maximum level after two days. Subsequently, interferons circulate through the bloodstream for 4-5 days.

Pharmacodynamics Kagocel has a powerful antiviral, antimicrobial and immunomodulatory effect if the medicine is used no later than the 4th day after the acute onset of the infectious disease. To prevent illness, the drug can be taken at any time, especially after contact with an infectious source.

Pharmacokinetics

The drug is used for oral administration, after a single dose of which activation of interferon production is observed and after 48 hours it reaches its maximum level.

When used orally, only 20% of the drug dose enters the general bloodstream. After a day, the main active ingredient of the drug accumulates in the tissue of the liver and lungs, the thymus gland, urinary organs and lymph nodes.

Pharmacokinetics of Kagocel causes slight accumulation in muscles, plasma part of the blood, myocardium, brain tissue, testes and adipose tissue. The low content of the active substance in the brain is due to the significant molecular weight of the drug, as a result of which it is not able to penetrate the BBB.

The drug is transported through the bloodstream in a bound state. Thus, its carriers can be lipids, which bind kagocel by 47%, as well as proteins - up to 37%. The remaining 16% of the drug is the unbound portion.

When taking the medication regularly for 5-7 days, the pharmacokinetics of Kagocel ensures maximum grouping of the active substance in the spleen and nodes of the lymphatic system.

The process of eliminating the drug is carried out mainly through the digestive tract. A week after starting to use the medication, 90% of the accumulated volume of the medication is eliminated from the body. The intestines remove 90% of the drug, and the kidneys remove the remaining 10%. Excretion of Kagocel by the respiratory system was not detected.

Use of Kagocel during pregnancy

Throughout pregnancy, a woman’s body undergoes dramatic changes affecting almost all organs and systems. During all 9 months, enormous strength is required from a pregnant woman to ensure optimal conditions for the full growth and development of the fetus.

In addition to changes in hormonal levels, mammary glands and organs of the female reproductive system, a woman’s immunity is also subject to great “tests”.

The use of Kagocel during pregnancy is contraindicated due to the fact that the medicine has an immunostimulating effect, which can negatively affect the course of pregnancy and the health of the fetus.

Despite the fact that the formation of organs is observed during the first three months of pregnancy, their growth and development occur during the rest of the time.

The use of Kagocel during pregnancy is prohibited at any time in order to avoid the threat of miscarriage and deterioration of the condition of both the pregnant woman and the fetus.

In addition, the medicine is not allowed for use during the period when the baby is breastfed. When a woman takes the drug, the risk of the active ingredient getting into the milk and, accordingly, into the baby increases, which is unacceptable at his age.

Contraindications

Due to the fact that each body is unique, reactions to taking a drug can also be completely different. The presence of such manifestations is due to the individual characteristics of the body. One of the contraindications to the use of Kagocel is considered to be a person’s hypersensitivity to the main active ingredient or auxiliary components.

In addition, contraindications to the use of Kagocel include children under 3 years of age, however, under 6 years of age it is not recommended to use the medicine for prophylactic purposes, only for the treatment of infectious respiratory diseases.

One of the most important contraindications is the period of pregnancy and breastfeeding, since the use of Kagocel can have a negative impact on the course of pregnancy and the health of the fetus.

It is worth remembering that the drug cannot be used by people who have lactase deficiency or intolerance to this enzyme. In addition, glucose-galactose malabsorption is considered a contraindication.

Contraindications to the use of Kagocel suggest a ban on the use of such drugs if there has already been a history of adverse reactions to taking the drug.

Side effects of Kagocel

Depending on the composition of the drug and a person’s heredity, side effects from the drug may occur when used. After a single or several doses of Kagocel, a person may experience an allergic reaction.

Its main clinical symptoms are systemic manifestations in the form of weakness, dizziness, headache, nausea and abdominal pain. Side effects of Kagocel can manifest themselves exclusively as rashes on the skin, tingling sensation, itching, increased sensitivity and slight swelling.

Side effects of Kagocel can manifest themselves at any age, depending on the level of sensitivity of the body and genetic predisposition.

As soon as any clinical symptoms that are not characteristic of Kagocel are observed, its further use must be discontinued. In addition, you should contact a specialist to conduct research and rule out overdose.

In general, Kagocel is tolerated quite well, provided that the dosage and recommendations for frequency of use are followed. Also, before using the drug, it is necessary to familiarize yourself with the contraindications of the drug to avoid worsening the condition.

Directions for use and doses

Kagocel is administered orally in the prescribed dosage with a small amount of water. The method of administration and dose depends on the person’s age and health status. In addition, the purpose of using the drug should be taken into account - for treatment or prevention, which also affects the dose.

For the therapeutic purpose of an infectious disease, for example, influenza or acute respiratory viral infection, in the first 2 days after the acute onset of clinical symptoms, it is recommended to take 2 tablets three times a day. Then in the next 2 days you should not take more than 1 tablet three times a day. The duration of the therapeutic course is 4 days, during which a person takes about 18 tablets.

The method of administration and dosage for prophylactic purposes are somewhat different. Thus, to prevent influenza and ARVI, it is recommended to take it in courses. You need to start with a single dose of 2 tablets for 2 days, after which you need to take a break for 5 days. Then repeat taking the drug again and take a break again. Thus, the preventive course can last from a week to a month.

For therapeutic purposes, children from 3 to 6 years old can take 1 tablet twice a day for the first 2 days, after which 1 tablet twice a day for another 2 days is sufficient. The total duration of the treatment course is 4 days, during which the baby takes 10 tablets.

Children over 6 years of age should take 1 tablet three times a day for 2 days, after which the dose is reduced to 1 tablet twice a day, also for 2 days. The child takes 10 tablets over 4 days.

For preventive purposes, the course is carried out in 7-day cycles for children over 6 years old. For 2 days you should take 1 tablet once a day, after which you need to take a break for 5 days and repeat the dose again. The duration of the preventive course is from a week to a month.

To treat herpes infection, adults need to take 2 tablets three times a day for up to 5 days. The duration of the treatment course is 5 days, during which the total number of tablets is 30 tablets.

When using tablets in the treatment of urogenital chlamydia as an auxiliary drug, it is necessary to maintain a dosage of 2 tablets three times a day for 5 days.

Overdose

If the dosage and frequency of administration are observed, an overdose is practically excluded. However, it is still recommended to know the clinical manifestations of an overdose in order to stop the drug in time and take measures to remove the drug as quickly as possible.

An overdose may result in nausea, vomiting, dizziness, weakness and pain in the stomach. In this case, it is recommended to go to the hospital for gastric lavage in a hospital setting, as well as “forced diuresis”.

Gastric lavage is carried out in order to remove any remaining drug that is still in the stomach and stop further absorption of the drug.

In this article you can read the instructions for use of the drug Kagocel. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Kagocel in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Kagocel in the presence of existing structural analogues. Use for the treatment and prevention of influenza, ARVI and herpes in adults, children, as well as during pregnancy and breastfeeding (lactation). Composition of the drug.

Kagocel- antiviral drug. Interferon synthesis inducer.

Causes the formation in the body of so-called late interferon, which is a mixture of alpha and beta interferons with high antiviral activity. Kagocel causes the production of interferon in almost all cell populations involved in the body's antiviral response: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When one dose of Kagocel is taken orally, the interferon titer in the blood serum reaches maximum values ​​after 48 hours. The body's interferon response to the administration of Kagocel is characterized by prolonged (up to 4-5 days) circulation of interferon in the bloodstream. The dynamics of interferon accumulation in the intestine when taking the drug orally does not coincide with the dynamics of circulating interferon titers. In the blood serum, the interferon content reaches high values ​​only 48 hours after taking the drug Kagocel, while in the intestine the maximum interferon production is observed after 4 hours.

The greatest effectiveness in treatment with Kagocel is achieved when it is prescribed no later than the 4th day from the onset of acute infection. For preventive purposes, the drug can be used at any time, incl. and immediately after contact with an infectious agent.

Compound

Copolymer of gossypol (one of the pigments of cotton, a natural polyphenol, toxic in free form) with carboxymethylcellulose + excipients.

Pharmacokinetics

When taken orally, about 20% of the administered dose of the drug enters the general bloodstream. 24 hours after oral administration, the drug accumulates mainly in the liver, and to a lesser extent in the lungs, thymus, spleen, kidneys, and lymph nodes. Low concentrations are observed in adipose tissue, heart, muscles, testes, brain, blood plasma. The low content in the brain is explained by the high molecular weight of the drug, which impedes its penetration through the BBB. It is excreted mainly through the intestines: 7 days after administration, 88% of the administered dose is excreted from the body, including 90% in feces and 10% in urine. The drug was not detected in exhaled air.

Indications

  • prevention and treatment of influenza and other acute respiratory viral infections in adults and children aged 6 years and older;
  • treatment of herpes in adults.

Release forms

Tablets 12 mg. A special pediatric form of the drug is not noted.

Instructions for use and dosage

The drug is taken orally.

For the treatment of influenza and ARVI, adults are prescribed 2 tablets 3 times a day in the first 2 days, 1 tablet 3 times a day in the next 2 days. A total of 18 tablets per course lasting 4 days.

Prevention of influenza and ARVI is carried out in 7-day cycles: 2 days - 2 tablets 1 time per day, break for 5 days. Then the cycle is repeated. The duration of the preventive course varies from 1 week to several months.

For the treatment of herpes, 2 tablets are prescribed. 3 times a day for 5 days. Total for a course lasting 5 days - 30 tablets

Side effect

  • allergic reactions.

Contraindications

  • pregnancy;
  • lactation period (breastfeeding);
  • children under 3 years of age;
  • lactase deficiency, lactose intolerance, glucose-galactose malabsorption;
  • increased individual sensitivity.

Use during pregnancy and breastfeeding

The drug is contraindicated for use during pregnancy and lactation (breastfeeding).

Kagocel, when prescribed in therapeutic doses, is non-toxic and does not accumulate in the body. The drug does not have mutagenic or teratogenic properties, is not carcinogenic and does not have embryotoxic effects.

Use in children

The drug Kagocel is contraindicated in children under 3 years of age.

For the treatment of influenza and ARVI, children aged 3 to 6 years are prescribed 1 tablet 2 times a day in the first 2 days, 1 tablet 1 time a day in the next 2 days. A total of 6 tablets per course lasting 4 days.

For the treatment of influenza and ARVI, children aged 6 years and older are prescribed 1 tablet 3 times a day in the first 2 days, 1 tablet 2 times a day in the next 2 days. A total of 10 tablets per course lasting 4 days.

In children aged 3 years and older, the prevention of influenza and ARVI is carried out in 7-day cycles: 2 days - 1 tablet 1 time per day, a break for 5 days, then the cycle is repeated. The duration of the preventive course is from 1 week to several months.

special instructions

To achieve a therapeutic effect, taking Kagocel should begin no later than the 4th day from the onset of the disease.

Kagocel combines well with other antiviral drugs, immunomodulators and antibiotics.

Drug interactions

With the simultaneous use of the drug Kagocel with other antiviral drugs, immunomodulators and antibiotics, an additive effect is observed (they enhance the effect of each other).

Analogues of the drug Kagocel

The drug Kagocel has no structural analogues for the active substance.

Analogs by pharmacological group (antiviral agents):

  • Avonex;
  • Alloferon;
  • Altevir;
  • Alfaferon;
  • Amizon;
  • Amiksin;
  • Anaferon;
  • Anaferon for children;
  • Arbidol;
  • Acyclovir;
  • Bonafton;
  • Valacyclovir;
  • Valtrex;
  • Vivorax;
  • Virazol;
  • Virolex;
  • Viferon;
  • Genferon;
  • Gerpevir;
  • Herpferon;
  • Groprinosin;
  • Zovirax;
  • Ingavirin;
  • Interferon;
  • Inferon;
  • Lavomax;
  • Medovir;
  • Nevirapine;
  • Neovir;
  • Oksolin;
  • Panavir;
  • Reaferon EC Lipint;
  • Relenza;
  • Remantadine;
  • Ribavirin;
  • Rimantadine;
  • Tamiflu;
  • Tiloron;
  • Famvir;
  • Famciclovir;
  • Cyclovir;
  • Epigen intimate;
  • Epigen labial;
  • Ergoferon.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.

Latin name: Kagocel
ATX code: J05A X
Active substance: Kagocelum
Manufacturer:"NEARMEDIC PLUS"
Hemofarm (Russia)
Conditions for dispensing from a pharmacy: Over the counter

Kagocel is a Russian modern medication with an antiviral effect, approved for treatment from 3 years of age.

Indications for use

The antiviral drug is developed for the treatment and prevention of influenza, acute respiratory viral infections and other viral infections. Designed for adults and children from 3 years of age.

The drug is also used to treat herpetic infections, but only in adult patients. Use for this purpose in pediatrics is prohibited.

Composition of the drug

One tablet contains 12 mg of Kagocel. The composition of other components that form the structure and properties of the pill is potato starch, calcium stearate, ludipress (includes lactose in the form of monohydrate, povidone and crospovidone).

Medicinal properties

The medicine has several effects at once - immunostimulating, antiviral.

The active component of Kagocel is a synthetic substance of the same name. Belongs to the polyphenol group and is an interferon inducer. The therapeutic effect is achieved due to the property of the substance to stimulate the body to produce various types of interferon - α, β, γ. In this way, better recognition and destruction of penetrating infection in various cells is achieved.

After taking a single dose, maximum activation of interferon production in the intestines is achieved after 4 hours, and peak plasma levels after two days.

Kagocel does not accumulate and does not have any negative effect on the body. It has practically no contraindications.

Due to its special structure (large molecule size), kagocel almost does not pass through the BBB, so its content in the tissues of the central nervous system is negligible.

The process of removing the substance from the body takes a long time - about a week. A significant portion is excreted in feces, about 10% in urine.

Kagocel: antibiotic or not

The drug is designed exclusively to stimulate the synthesis of interferon. It does not have any antibacterial properties. Therefore, the drug is not an antibiotic.

Does Kagocel affect men's health?

There is a widespread belief that the drug should not be given to boys and men, as it provokes infertility. They say that in this way the birth rate is controlled. It is difficult to say where this information came from and why it turned out to be tenacious. This is probably due to the fact that Kagocel contains gossypol. A natural substance obtained from cotton actually has the property of preventing conception, as it negatively affects spermatogenesis. But the drug contains gossypol of artificial origin, and therefore lacks contraceptive quality. In addition, over more than 10 years of existence, Kagocel has passed many tests that confirmed its safety. Clinical observations and animal experiments also did not confirm harm to men's health. Therefore, Kagocel is included in the list of vital drugs.

Release forms

Average cost of drugs: (10 pcs.) – 225 rubles.

The drug is developed in the form of tablets - pills convex on both sides. Color can vary: from white with a beige tint to pale brown. The structure contains inclusions of a more saturated color. The pills are packaged in blister packs of 10 pieces. A cardboard pack may contain 1, 2 or 3 tablets with an annotation.

Mode of application

Before you start taking an antiviral drug, it is advisable to get a prescription or consult with your doctor. If this is not possible, then you should take Kagocel tablets according to the instructions for use.

The timing of meals does not affect the effectiveness of the drug, so Kagocel can be taken orally at any time - before or after meals. It also does not matter in what form the tablet enters the body - chewed or whole. This does not affect the therapeutic effect.

Therapy for adult patients (over 18 years of age):

If during this time the symptoms do not disappear, but, on the contrary, persist or worsen, you should see a doctor. Perhaps a secondary infection has occurred, and the course needs to be supplemented with other medications.

Take 2 tablets three times a day. for 5 days. It is not recommended to prolong taking the pills on your own. The possibility of a repeat course should be discussed with your doctor.

How to take Kagocel for children

Features of therapy for children are determined not only by the severity of the condition, but also by the age of the child. Manufacturers recommend giving Kagocel to children according to the therapy regimen they have developed:

  • From 3 years to 6. The therapeutic course takes 4 days: in the first two days, take the highest daily dosage - drink 1 tablet twice a day, and in the remaining two days - once 1 pill.
  • From 6 to 9 years. The course also takes 4 days: 2 days – 3 r. 1 tablet each, in the next 2 days - 2 rubles. 1 table each As a result, you will need to take 10 pills during the course.

How to drink Kagocel for disease prevention

In addition to treatment, it is recommended to drink the drug for preventive purposes - to prevent the incidence of influenza and ARVI. Moreover, it can be used both during the epidemic season and after one-time contact with patients. After the first dose, the body activates the synthesis of its own interferon, which helps to significantly reduce the intensity of painful symptoms.

To avoid getting sick, they act according to the following scheme: take the drug for two days, then follow a 5-day break, after which they resume taking the drug for 2 days.

During the course, adults are supposed to take 2 tablets once a day, children - only 1 pill.

The duration of preventive measures should be determined by the attending physician, based on the indications. If necessary, it can take from 7 days to several months.

During pregnancy and breastfeeding

To date, no studies have been conducted on the effects of an antiviral drug on the body of a woman expecting a child. Therefore, Kagocel is prohibited for use during pregnancy at all stages.

It is also unknown how it affects lactation. Nursing mothers who are forced to take Kagocel while breastfeeding are advised to stop breastfeeding for the period of treatment.

Contraindications

The use of Kagocel medicine is prohibited if you have:

  • Increased reaction of the body to the constituent components of the drug
  • Children under 3 years of age (due to insufficient knowledge of the effect of drugs on the body)
  • Congenital lactase deficiency, lactose intolerance, glucose-galactose malabsorption syndrome.

Precautionary measures

The therapeutic effect of Kagocel largely depends on the time of initiation of administration. For it to have maximum effect, it must be taken no later than 4 days of illness. Manufacturers advise taking it at the first suspicion of illness - as soon as the first signs of deterioration appear.

You cannot drink drugs uncontrollably. Only a doctor should determine the need for its prescription, as well as how often Kagocel can be taken, based on the indications, diagnosis and other factors.

It is possible to use Kagocel during breastfeeding only if you stop lactation, since it is not yet clear how the active substance affects the infant’s body.

The drug is not intended for the treatment of herpes in children. For this category of patients, Kagocel is used only for the treatment and prevention of influenza and acute viral infections.

The course should not be interrupted at the first signs of improvement in well-being. The absence of symptoms after early interruption of treatment does not indicate recovery. To avoid complications, the prescribed therapy should be completely followed.

Cross-drug interactions

In the treatment of viral diseases, Kagocel monotherapy is insufficient, so the prescription of other medications is required. Kagocel can be combined with antibiotics, immunomodulators and various antiviral drugs. The compatibility of Kagocel with other drugs does not distort the effect of medicinal properties.

Kagocel and alcohol

The vast majority of medications cannot be combined with alcohol in any form (drinks or alcohol-containing medications). In relation to Kagocel, such a restriction does not exist, since there is no interaction between them.

However, this does not mean that such combination with alcohol is absolutely safe. The drug stimulates the active production of interferons, which affects the state of the central nervous system. The toxic effect of ethanol, coupled with the effect of the drug, can trigger the development of a depressive state, increased irritability and nervousness, mental changes or clouding of consciousness.

Therefore, during treatment with Kagocel it is necessary to exclude the intake of alcohol into the body. In addition, given that the active substance of the drug is eliminated from the body within several days (on average about 4-5), during this period you will also have to hold off on drinking alcohol.

Side effects

As a rule, Kagocel is well tolerated by the body. In isolated cases, allergic reactions are possible in people with an increased sensitivity threshold.

If during the therapeutic course any undesirable signs of deterioration in well-being occur, Kagocel should be discontinued and consult a doctor to clarify the further treatment regimen.

Overdose

If the recommended dosage and frequency of administration are observed, intoxication is unlikely. However, it is necessary to understand how the symptoms of an overdose of Kagocel manifest themselves so that it is possible to quickly provide assistance to the victim.

After taking overdoses of an antiviral drug, the following may develop:

  • Nausea
  • Vomiting attacks
  • Vertigo
  • Head pain
  • Discomfort or abdominal pain
  • General weakness.

To eliminate the cause of the malaise, it is necessary to take measures to remove the medicine from the body. Drinking plenty of fluids and inducing vomiting helps. If necessary, doctors can perform gastric lavage and prescribe forced diuresis.

To avoid an accident, care should be taken when treating children, as they are especially sensitive to medications.

Conditions and shelf life

The shelf life of the medicine is 4 years from the date printed on the packaging. Keep the drug away from light, protect from high humidity, and maintain a storage temperature of up to 25 ° C.

Analogs

To replace Kagocel with another medicine for influenza, you must consult a doctor. Ingavirin, Interferon, Grippferon, Ergoferon, etc. have a similar immunostimulating effect.

Arbidol Maximum

"Dalkhimpharm", "Pharmstandard-Leksredstva" (RF)

Price:(10 capsules) 425 rub.

The antiviral agent promotes the activation of interferon formation and has a suppressive effect on influenza pathogens. It has proven itself well in the treatment of bronchitis, pneumonia, and herpetic infections. It is also used for preventive purposes during postoperative periods to increase immunity levels.

The active substance is umifenovir.

The drug is approved for use from the age of 12, and is prohibited during pregnancy and lactation. Available in capsule form.

Pros:

  • Well tolerated
  • Almost no side effects.

Flaws:

  • Pregnant women should not drink
  • A little expensive.

Every parent has a desire to protect their child from various diseases. For this purpose, modern doctors prescribe antiviral drugs that have immunomodulatory activity. This is “Kagocel” for children and its analogues. Instructions for using this medication will be presented to your attention in the article. You will learn about what this drug is and how it works. It is also worth mentioning what Kagocel looks like. Instructions for use, indications, composition see below.

What does the medicine look like?

What is Kagocel? Instructions for use and description of the drug indicate that the medicine is available in tablet form. The color of the pills ranges from white to cream or brown. Each capsule has its own inclusions and dividing line.

10 tablets are packaged in a single plate, which fits into the package. The pack contains the name “Kagocel”. An abstract is included in each package.

Composition of the drug

What is children's Kagocel made of? The instructions for use indicate that the active substance is the component of the same name. It is he who has the main effect on the body of the patient receiving treatment. The amount of the main substance in one tablet is 12 milligrams.

You may also find additional compounds in the medicine. Among them are potato starch in an amount of 10 mg, calcium stearate weighing 0.65 mg, and Ludipress up to 100 mg. Be sure to pay attention to the ingredients when using any medication.

When is the medication "Kagocel" prescribed?

Instructions for use, reviews from doctors indicate that the drug can be used to treat various pathological conditions or taken for preventive purposes. The main indications for the use of tablets are the following cases:

  • influenza of various types;
  • viral diseases;
  • herpes of different localization;
  • decreased immunity;
  • bacterial lesions (in complex therapy).

For the children's medicine "Kagocel", the instructions for use clearly describe all situations in which the use of the drug is necessary. However, this does not mean that you can give this medicine to your child yourself. Before using the described medication, you should definitely consult your doctor and get individual recommendations.

Contraindications: are there any?

Many doctors report that children's "Kagocel", the instructions for use of which are described in the article, are very well tolerated by patients. In most cases, the product does not cause a negative reaction. However, the medication has its contraindications. Some sources report that the tablets are not prescribed to children under six years of age. Others specify the age of three years as a limit.

The drug should not be taken if you are hypersensitive to one or more of its components. The medication should not be used for children who have congenital or acquired lactase deficiency.

Possibility of unpleasant reactions

Children's "Kagocel" (the instructions for use indicate this) usually does not cause side effects. The drug is well tolerated by young patients. However, like any medicine, it can lead to allergies in a child.

If the medicine is used incorrectly and overdose, there is a risk of headaches, abdominal cramps and gas formation. If you give the medicine to a child with cow protein intolerance, stool upset and other unpleasant symptoms may occur. If these appear, you should immediately contact your doctor and receive appropriate prescriptions.

"Kagocel" (children): instructions for use

The price of the drug will be presented to your attention later. Before this, it is worth talking about how to use the medicine. The children's drug is also used for adults. The dose of medication for children from 6 to 12 years old is one tablet three times a day. This scheme must be followed for 2 days. After this, the medicine is taken for another 2 days, 1 capsule. For the full course you will need one package of medication.

Children from 3 to 6 years old are recommended to use the medicine according to the following scheme. In the first two days - one capsule twice. After this, take 1 capsule per day for another 2 days. The total number of tablets is 6. This is less than one package.

If the medicine is prescribed to adults, the following scheme is used. Two capsules three times a day for the first 2 days. Then one tablet three times a day. The course will require 18 pills. That's almost two packs.

Use for babies: reviews from doctors

As you already know, information from the annotation for the drug varies. Some instructions state that the tablets can only be given to children over six years of age. Other sources allow treatment as early as three. What do doctors say about this?

Doctors report that the manufacturer bases its restrictions only on the fact that no studies have been conducted among children. As you know, a new drug is always tested on patients. Only after this is information about contraindications and side effects compiled. Doctors say that even when using the medication, no negative reaction was observed among children in the first year of life. However, only an experienced pediatrician should allow such a correction. In this case, an individual dosage of the medicine is always selected.

Cost and analogues

You have learned what the instructions for use and reviews say about the drug “Kagocel”. Indications for use and composition are also described above. What is the cost of packaging the medicine? The average price of a product is 215 rubles. If treatment is performed on an adult, then the full course will cost you 400-500 rubles.

Among the absolute analogues of the drug, which are approved for use in children, one can highlight the drug “Tsitovir”. This is an oral syrup with an identical composition. You can also replace the medicine with the tablets “Anaferon”, “Cycloferon”, “Isoprinosine”, “Licopid” and others. They have a different composition, but the same effect on the patient’s body.

About half of this time occurs in November-December. At this time of year, the maximum spread of influenza and ARVI is observed.

The pace of modern life in large cities requires a person to save time and effort. Undoubtedly, the above diseases have a very unfavorable effect on health and general well-being. However, despite the fact that colds and flu are considered relatively benign diseases, preventing or alleviating these diseases is not an easy task. Once in the body, the virus multiplies quickly, provoking a number of symptoms: rhinitis, cough, headache, loss of strength and loss of general tone, hyperthermia.

Today, people increasingly need effective and convenient drugs that will prevent, or minimize and alleviate the course of the disease.

Humanity still does not have drugs at its disposal that can cope with viral infection with 100% efficiency. Today, antiviral medications are imperfect, but their number and variety are growing, and their effectiveness is increasing every year.

Russian antiviral drug Kagocel- This is another domestic drug for colds, flu and acute respiratory diseases.

Most antiviral drugs sold in Russia have a positive effect only when treatment is started early (on days 1-2 of the disease). Kagocel, in turn, is effective at any stage of the disease. It not only alleviates and shortens the course of the disease, but also significantly reduces the likelihood of complications. In addition, the drug is safe and does not cause side effects (with the exception of rare cases of allergic reactions). Therefore, it is approved for use in children over 3 years of age.

Kagocel was developed by the Nearmedic Plus company (RF), created on the basis of the Research Institute of Epidemiology and Microbiology named after. N.F. Gamaleya RAMS. The drug was approved by the Russian Ministry of Health and Social Development as a drug recommended for the prevention and treatment of acute respiratory viral infections, influenza, as well as for the treatment of pathologies associated with herpes virus infection. In addition, the drug was included in the list of vital and essential medicines, due to which it was included in the state system. procurement Produced since 2005. Available in pharmacies without a prescription.

Interferon inducers

Since the production of interferon is one of the first immune responses to viral infection, stimulators of the production of this protein occupy a special place among antiviral drugs.

Interferon inducers do not cause an immune response and are not capable of causing an overdose. Once in the body, drugs of this group stimulate the production of interferons in optimal quantities.

Interferon inducers are divided into two groups: artificial and natural. The drug Kagocel, in turn, belongs to the second group. It stimulates the production of alpha, beta, and gamma interferons in the human body, which have a high antiviral effect.

Mechanism of action of the drug

Since during the preparation of the drug the active substance is bound to the cellulose base, Kagocel is practically not absorbed in the digestive tract (no more than 20% of the active substance is absorbed).

Kagocel enhances the activity of interferons (specific cellular proteins that protect the body from viruses) in the body.

By acting on the body, Kagocel induces the production of interferons in the body, which have a pronounced antiviral effect. The effect of the drug lasts 5-7 days. Due to the long-lasting effect of the drug, it is convenient to use it for the prevention of acute respiratory diseases and influenza in small doses, short courses and for any period of contact with the spreader of the disease.

Kagocel enhances the production of interferon in all cells that are part of the antiviral immune system: in B-cells, macrophagocytes, granular leukocytes, fibroblasts, endothelial cells.

However, the effect of Kagocel is not limited to the induction of interferon production. The drug also stimulates the release of cytokines, activates cellular immunity and natural killer cells.

The effect of the drug on the body lasts on average 5 days, during which the produced interferon circulates in the circulatory system. At the same time, the active substance accumulates in the intestines 4 hours after administration. After a single use of the drug in a standard dose, the concentration of interferon in the blood increases significantly, reaching a maximum after two days. The maximum concentration of interferon in the blood persists for 2-3 days.

According to the results of numerous clinical trials, with repeated daily use of the drug, the active substance enters various organs and tissues in uneven proportions. A day after entering the body, most of the active substance is concentrated in the liver. Also, in small concentrations, the drug accumulates in the lungs, spleen, kidneys, thymus gland and lymph nodes. The drug accumulates least in muscle tissue, heart, adipose tissue, brain and blood. When taken orally, approximately 20% of the active substance enters the bloodstream. In the blood, 47% of kagocel is bound to blood lipids, 37% to proteins, 16% circulates in free form. The molecules of kagocel are quite massive, so it does not penetrate the blood-brain barrier, which prevents it from entering the brain. The drug is eliminated mainly through the digestive tract. 6-7 days after completion of the course of treatment, approximately 88% of the active substance is removed from the body. In this case, 90% is excreted through the gastrointestinal tract, and 10% through the kidneys. Excretion of the drug through the lungs has not been established.

Indications

  • For adults, Kagocel is indicated for the treatment of viral infectious diseases, as well as the prevention of colds, flu and other acute respiratory infections, for the treatment of diseases associated with herpes virus infection;
  • for children over 6 years of age, the drug is indicated for the prevention and treatment of influenza, colds and other acute respiratory diseases;
  • Children 3-6 years old are indicated for the treatment of influenza, colds and other acute respiratory infections.

Contraindications

  • hypersensitivity to the components of the drug;
  • age up to 3 years;
  • pregnancy period;
  • intolerance to glucose and galactose.

Directions for use and doses

Kagocel is administered orally.

For adults
For flu, colds and other acute respiratory infections, take two tablets. 3 times a day for the first 2 days, then one tablet 3 times a day. The duration of the course is 4 days.
To prevent influenza, colds and other acute respiratory infections, 2 tablets are prescribed. 1 time per day for 7 days. Then a 5-day break is taken, after which, if necessary, the 7-day cycle is repeated. The duration of the preventive course is determined by the attending physician and ranges from 7 days to 3-5 months.
To treat herpes virus infection, take 2 tablets. 3 times a day. The duration of the course is 5 days.

Children 3-6 years old
For flu, colds and other acute respiratory infections, take 1 tablet. 2 times a day for two days, then 1 tablet. per day. The duration of the course is 4 days.

Children over 6 years old
For flu, colds and other acute respiratory infections, take 1 tablet. 3 times a day for two days, then 1 tablet. 2 times a day.
To prevent influenza, colds and other acute respiratory infections, 2 tablets are prescribed. 1 time per day for a week. Then a 5-day break is taken, after which the 7-day cycle is repeated. The duration of prophylaxis depends on various factors and is determined by the attending physician. Prevention lasts from 7 days to 3-5 months.

Overdose

In case of an overdose of Kagocel, drinking plenty of fluids followed by inducing vomiting is indicated. It is strongly recommended that you seek medical advice before resuming treatment.

Side effects

Rarely - an allergy to the components of the medication.

Interaction with other drugs

The drug Kagocel combines well with immunostimulants, antibiotics (complements their effect), and other antiviral medications.

special instructions

The maximum therapeutic effect of the drug is achieved if treatment is started within a period not exceeding 3 days from the onset of the acute phase of the disease. To prevent influenza, colds and other acute respiratory diseases, the drug is used at any time, or after contact with the spreader of the disease. Before use, you should consult a specialist.
Reviews

I took Kagocel at the first symptoms of ARVI, unfortunately it didn’t help me, I gave it to children too, I didn’t feel any visible effect, but at the pharmacy it was highly recommended, sometimes you buy an unknown drug, but it’s really effective, for example, Tiloram once helped me like that.

If you start drinking it at the very beginning of the disease before the 4th day, then the effectiveness of Kagocel is at its best. With the use of the drug, colds and viruses have avoided me for a couple of years now.

This year I got sick for the third time, but for the first time I decided to get treatment and not just endure the sores on my legs. The doctor prescribed Kagocel in the complex. Thanks to him, I was sick not just for two weeks, but for only 5 days. In fact, my first symptoms never developed into a full-fledged cold. I think that in my case Kagocel really helped.

Apparently viruses mutate, because ascorbic acid doesn’t help me at all now, and this despite the fact that in childhood, when I had a cold, it was the only treatment I had. Now, if I don’t start taking an antiviral, I might get sick for a week or two. Fortunately (the year before last), I discovered Kagocel, and that’s the only way I can save myself. With this drug I recover in 3-4 days, quickly and always guaranteed, and I don’t need more.

One of the best and safest antiviral drugs. I personally like it. I drink myself and force my husband, but he needs to be controlled, he always forgets.

Kagocel helped me a lot in early spring. The cold struck quite unexpectedly and, as usual, at the most inopportune moment, a few days before the wedding of my only sister. The doctor recommended that I start taking Kagocel among all the antiviral medications. With him, in 4 days all the symptoms disappeared and I returned to life.

For several years now, thanks to Kagocel, I have been living without colds, flu and ARVI. Of course, I sneeze and sometimes snot flows, but for my bones or body to ache, and even more so for my temperature to rise, this is no longer the case. This is an excellent prevention against viral infections. You can, of course, try to support the body using folk methods, but I would still advise drinking Kagocel and using raspberries and currants as auxiliary means.

I took Kagocel according to the regimen indicated on the package. I thought that everything would pass much faster, but alas, I lay in bed for 5 or 6 days. But still, the drug helped, because... my runny nose and sore throat went away by the 4th day, although usually this all drags on for at least two weeks, even with a general improvement in well-being.

The year before last, I was careless and allowed a common cold to cause severe complications in my ears, and then I had to treat otitis media for a long time. Therefore, now I am wary of viral infections. In order to protect myself from germs, I drink Kagocel. My sister, with his help, has been carrying out preventive care for several years in a row, I didn’t even know. She claims that she gets sick much less often. And, in a good moment, I also stopped getting sick with Kagocel.

Whenever I am sick with ARVI, I buy Kagocel, it has proven itself well, with it we recover quickly, easily and without complications. It has been tested against dozens of diseases in two years, and it has never failed.

I read that Kagocel is not so harmless at all... in this regard, I prefer to drink Galavit if I have a cold, a good, proven antiviral. Although, of course, if you are not lazy, it is better to drink for prevention.

For the second year now, before the start of the winter epidemics of influenza and ARVI, I have been taking Kagocel for prevention, and as a result, I have never been seriously ill in these two years. In general, I didn’t stop getting sick, but it was more of a mild cold, not acute at all, and certainly not the flu. So Kagocel performs its preventive function, as well as it cures, I didn’t have to find out, since there was no particular need for it.

I caught a cold, felt very bad, bought Kagocel for treatment and already on the second day there were no body aches, no headaches, no chills... no symptoms at all. Without Kagocel, I’m sure I would have been fully ill, but I ended up with a slight fright.

For Kagocel to work, it must be taken exactly according to the instructions, strictly in recommended doses, and always with the first symptoms of the disease. You will do everything exactly, you will definitely not complain about the ineffectiveness, because Kagocel can quickly improve your health.

I have been taking Kagocel as a preventive drug for several seasons now, and I am satisfied with the effect. Since the time I met him, I have never caught a cold. True, for the sake of health, I also gave up cigarettes and started going to the gym. And, as a result, the second half of winter, and I didn’t even have a runny nose, not that more serious symptoms appeared.

I was treated with Kagocel twice and these were my mildest ARVIs, it all started very frighteningly - high fever, runny nose, terrible cough, weakness, I constantly wanted to sleep, I woke up only to drink water and take Kagocel, and the very next day I felt much better, a day later, the temperature returned to normal, my health improved, and already on the 5th day my sick leave was closed. And without Kagocel, with such symptoms, I was sick for one and a half to two weeks, the difference is certainly noticeable.

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