Sodium bicarbonate. Soda solution for intravenous injection - indications

Soda (or sodium bicarbonate) is used in therapy as a means of alkalizing an acidified environment. Soda solution for intravenous administration is a colorless transparent liquid. For intravenous injections, 4% liquid for infusion is used. Also, a soda solution is administered together with drugs that have acidic pH to neutralize the causes of post-injection phlebitis.

Causes of acidosis

Why does an imbalance of acid-rich hormones towards oxidation (acidosis) occur? The causes of the pathology may be:

• preservatives and pesticides;
• unfavorable environment;
• drug abuse;
• emotions of fear, anger and anxiety.

Why does a disturbance in the emotional sphere lead to acidosis? Because with negative emotions, the activity of the kidneys is disrupted, which are unable to coordinate the alkaline balance of the blood. Severe acidification of the blood leads to various ailments.

Important! Against pathological acidification of the body, sodium bicarbonate preparations are used orally, topically, rectally or in the form of injections.

Indications for use

Soda injections are prescribed to overcome metabolic acidosis in diseases:

• intoxication of body tissues;
• in the postoperative period;
• with large blood losses;
• blood thickening;
• with prolonged hyperthermia;
• skin burn;
• with the development of acidosis;
• diabetic coma;
• with diarrhea complicated by vomiting;
• kidney/heart damage;
• severe hangover syndrome;
• severe form of neonatal hypoxia.

Soda solution is administered diluted or undiluted: prescribed according to the intensity of the symptoms of acidosis (acidification). Dilute the solution with a five percent glucose preparation in a 1:1 ratio.

For adults, soda solution is administered rectally or intravenously. For newborns - intravenously. The dose of the drug for adults is 200 ml per day (in two doses) by intravenous injection or in drip enemas - two doses of 50/100 ml.

The maximum daily dosage for adults is 315 ml. The dosage of the drug for newborns and small children is calculated taking into account body weight.

When the acid-base indicator shifts towards oxidation as a result of alcohol poisoning, a soda solution is administered as a dropper. Alcohol poisoning concentrates fatty acids, pyruvic and lactic acid, as well as glycerol in the blood.

Processing of alcoholization products accumulates in body tissues and causes symptoms of severe poisoning with consequences. The development of such a condition can lead to systemic destruction of the body and death. When relieving a severe hangover, undiluted sodium bicarbonate is administered orally.

Adverse reactions and overdose

Soda solution in the form of injections can cause complications of varying degrees of intensity:

• stomach pain, heaviness, bloating;
• nausea and vomiting;
• headache and dizziness;
• excessive worry and fear;
• alkalosis and tetanic convulsions.

A solution of soda when administered dropwise does not cause alkalosis, at least the manifestations of such a reaction are not pronounced.

In patients with acute kidney/heart disease, edema and heart failure may occur.

Application topically and internally

Locally, a soda solution is used to soften the epidermis and cleanse it of impurities. External use helps cleanse the nasopharynx during inflammatory processes caused by rhinitis and sore throat. Also, a solution of soda in the form of rinses and lotions is used for:

• conjunctivitis;
• stomatitis;
• inflammation of the gums.

Internal use extinguishes excess acid in the secretion of the stomach, dissolves pathological mucus and enhances motility. Taking the drug internally promotes a shift in the pH of the environment to the alkaline side, loosens cell membranes, neutralizes toxic substances and promotes the active removal of ballast elements to the outside.

For gastrointestinal diseases, sodium bicarbonate is used internally for:

• catarrhal gastritis;
• expansion of the stomach.

Local use of bicarbonate is indicated for:

• external treatment of furunculosis;
• cracks and scuffs on the heels;
• insect bites;
• fungal infections of the feet.

Important! It is not recommended to use sodium bicarbonate in large quantities to relieve heartburn. Frequent use of the powder causes the opposite effect - acid rebound. With this phenomenon, excess acid formation occurs, causing bloating and an unpleasant sensation of distension in the stomach.

In conclusion, here is a video about the treatment of cancer with sodium bicarbonate:

Intravenous urography - examination of the urinary system Intravenous laser irradiation of blood, indications and contraindications Is it possible to do Pentaxim after Infanrix - the answer to a difficult question

active substance: sodium bicarbonate;

100 ml of solution contains 4 g of sodium bicarbonate;

Excipients: disodium edetate, carbon dioxide, water for injection;

ionic composition per 1000 ml of the drug: sodium ion - 476 mmol, bicarbonate ion - 476 mmol.

Dosage form

Solution for infusion.

Basic physical and chemical properties: transparent colorless liquid. Theoretical osmolarity is about 952 mosmol/l, pH 7.4-8.5.

Pharmacotherapeutic group

Blood substitutes and perfusion solutions. Electrolyte solutions. Code ATX B05X A02.

Pharmacological properties

Pharmacodynamics.

A remedy for restoring the alkaline state of the blood and correcting metabolic acidosis. When sodium bicarbonate dissociates, a bicarbonate anion is released, it binds hydrogen ions to form carbon acid, which then breaks down into water and carbon dioxide, which is released during respiration. The solution, brought to a pH of 7.7-7.9, prevents spasmodic swelling and ensures smooth correction of acidosis while increasing alkaline blood reserves. The drug also increases the excretion of sodium and chloride ions from the body, increases osmotic diuresis, thickens urine, and prevents the sediment of uric acid in the urinary system. The bicarbonate anion does not penetrate inside the cells.

Pharmacokinetics.

Not researched.

Indications

Uncompensated metabolic acidosis in intoxications of various etiologies, severe postoperative period, widespread and/or deep burns, shock, diabetic coma, prolonged diarrhea, uncontrollable vomiting, acute massive blood loss, severe liver and kidney damage, prolonged febrile states, severe hypoxia of newborns. The absolute indication is a decrease in blood pH below 7.2 (normal 7.37-7.42).

Contraindications

Metabolic or respiratory alkalosis, hypokalemia, hypernatremia.

Special Security Measures

The drug should be used under the supervision of laboratory tests of acid-base and electrolyte balances.

Interaction with other drugs and other types of interactions

May enhance the antihypertensive effect of reserpine.

Features of application

It is necessary to monitor the acid-base and electrolyte balances of the blood. Patients with concomitant heart or kidney disease may develop heart failure and edema. If acidosis is resolved too quickly, particularly if ventilation is compromised, the rapid release of CO2 may worsen cerebral acidosis.

Use during pregnancy or breastfeeding

There is no experience with the use of the drug during pregnancy or breastfeeding. Prescribe if the expected benefit to the mother outweighs the potential risk to the fetus. It is possible to use the drug during breastfeeding only for health reasons.

The ability to influence the reaction rate when driving vehicles or other mechanisms

Data are not available due to the use of the drug exclusively in a hospital setting.

Directions for use and doses

Prescribe to adults intravenously or rectally; for children - intravenous drip. Depending on the severity of acidosis, use the drug with undiluted or diluted 5% glucose solution in a 1:1 ratio.

For adults, administer intravenously at a rate of approximately 60 drops per minute, up to 200 ml per day. Calculate the dose depending on blood gas parameters using the formula:

Volume of 0.5 molar buffered sodium bicarbonate 4.2% in ml =

base deficit (-BE) X kg of patient's body weight X 0,3 X 2

(a factor of 0.3 corresponds to a particle of extracellular fluid compared to total fluid).

For children over 1 year of age, administer at a dose of 5-7 ml per 1 kg of body weight.

The maximum dose of the drug for adults is 300 ml (with increased body weight - 400 ml) per day, for children from 100 to 200 ml depending on body weight.

Children

Use for children aged 1 year and older.

Overdose

If the dose of the drug is exceeded, hyperalkalosis, hypernatremia and hyperosmia, and tetanic disorders may develop. If signs of alkalosis appear (convulsions, including with manifestations of tetany, agitation, decreased potassium and calcium levels and increased sodium levels in the blood, increased pH levels), stop administering the drug and, if necessary, administer an isotonic sodium chloride solution or 5% glucose solution . If there is a danger of developing tetany, administer 1-3 g of calcium gluconate intravenously to adults.

Adverse reactions

Nausea, vomiting, anorexia, stomach pain, headache, anxiety, hypertension, convulsions, alkalosis.

Best before date

Storage conditions

Store at a temperature not exceeding 25 °C out of the reach of children. Do not freeze. Do not use the solution if there is sediment.

Incompatibility

The drug is incompatible with solutions of: ascorbic acid, nicotinic acid, cisplatin, codeine phosphate, dobutamine, dopamine, magnesium sulfate, morphine sulfate, norephedrine bitartrate, potassium salt of penicillin G, streptomycin sulfate, tetracycline. The drug is not recommended for use with drugs that have an acidic reaction and alkaloid salts. Do not mix with phosphate solutions.

Package

100 ml or 200 ml, or 400 ml of the drug in bottles.

Vacation category

On prescription.

Manufacturer

Manufacturer's location and address of place of business

Vinnitsa, st. A. Ivanova, b. 55.

Applicant

Closed joint-stock company "Infusion", Ukraine.

The compound sodium bicarbonate (bicarbonate) is nothing more than ordinary baking soda. In everyday life, it is often used for various purposes: it perfectly cleans dishes, it is put into dough (for splendor). However, this substance has long been used for medical purposes. In the human body, soda neutralizes acids, significantly increases alkaline reserves, and helps maintain acid-base balance. In humans, the pH level of acidity in the blood is normally in the range of 7.35-7.47. When the value is less than 6.8 (highly acidified blood - severe acidosis), the person may die. The medicine "Sodium bicarbonate" eliminates acidosis.

Baking soda

In medicine, sodium bicarbonate (formula - NaHCO 3) of a high level of purification is used. It should not be confused with the compound calcium bicarbonate - they are different substances. According to the requirements of the State Pharmacopoeia (eleventh edition), the mass fraction of sodium bicarbonate in the drug should not be less than 99.3%. The admixture of ordinary baking soda (Na 2 CO 3) should not exceed 0.5%. Minor content of sulfates and chlorides is also allowed. To determine the intended purpose of the medicine “Sodium Bicarbonate”, you should refer to the pharmacological reference book of M. D. Mashkovsky (“Medicines”, 1985). This medicine belongs to the following pharmacological categories: perfusion and plasma-substituting compounds, antacids, drugs for regulating water-electrolyte and acid-base balances. This medication is supplied in tablets, powder, injection solutions, and suppositories.

pharmachologic effect

The medicine "Sodium bicarbonate" is an antacid. When taken orally, it interacts with hydrochloric acid (HCl) of gastric secretion, neutralizing the latter. The drug also increases the level of Cl- and Na+ excretion and osmotic diuresis, shifts the reaction of bronchial mucus to the alkaline side, reduces the viscosity of sputum, improves its separation and expectoration, and increases bronchial secretion. The drug “Sodium Bicarbonate” relieves pain from duodenal and gastric ulcers. The antacid effect occurs very quickly, but is only short-term. Moreover, carbon dioxide (CO 2), which is formed when sodium bicarbonate neutralizes hydrochloric acid, irritates the gastric mucosa, causes belching and discomfort in the epigastric zone, stimulates an increase in gastrin secretion with activation of secretion (secondary). When absorbed, the drug provokes the development of alkalosis. The medicine “Sodium Bicarbonate” alleviates the symptoms of air and sea sickness. The drug alkalinizes the urine, which causes precipitation of uric acid in the urinary ducts.

Indications

The drug is prescribed for the following diseases:

• excess acidity of gastric secretions;
• metabolic acidosis (including those caused by infections, intoxications, diabetes mellitus, postoperative);
• stomach ulcer;
• various inflammatory processes of the mucous membranes (oral cavity, eyes, upper respiratory tract);
• duodenal ulcer;
• to liquefy bronchial secretions;
• to eliminate discomfort in uncomplicated inflammation of the urinary tract;
• for alkalizing urine;
• as an ear wax remover;
• with renal tubular acidosis;
• with urate and cystine kidney stones.

Contraindications

The use of sodium bicarbonate is contraindicated in case of hypersensitivity, hypocalcemia (increases the risk of alkalosis, tetanic convulsions), alkalosis, hypochloremia (large losses of Cl - due to vomiting or prolonged decrease in absorption in the gastrointestinal tract).

Use of medication during lactation and pregnancy

Since sodium bicarbonate can cause alkalosis, when deciding whether to prescribe the drug during pregnancy, the level of risk and benefit must be assessed. Based on the level of effect on the fetus, this medicine belongs to Category C according to the FDA. It is not known for certain whether it can penetrate into mother's milk. Therefore, unless absolutely necessary, it is better not to prescribe sodium bicarbonate to pregnant women. There is no reliable information about its effect on the fetus.

Side effects

With prolonged use, there is a high risk of developing alkalosis and its clinical manifestations: nausea, loss of appetite, vomiting, abdominal pain, headaches, anxiety; in severe cases - tetanic convulsions. An increase in blood pressure is also possible. As a rule, when using the drug in the form of suppositories, a laxative effect, the urge to defecate, flatulence, diarrhea, and rumbling are observed.

Peculiarities

It is recommended to use the medication only as prescribed by a doctor. Self-medication can be dangerous. It should be borne in mind that unsystematic and uncontrolled intake of sodium bicarbonate can be harmful to health. Even in cases where the medicine is prescribed by a doctor, at the first manifestations of alkalosis symptoms, you need to interrupt treatment or at least take a break. Taking medications to correct acidosis requires monitoring of acid-base balance. Long-term systematic use is also not recommended due to the likelihood of urine alkalization. This increases the risk of forming phosphate stones. A shift of acid-base balance to the alkaline side during short-term therapy does not cause clinical symptoms. However, with chronic renal failure, the patient's condition can seriously deteriorate. Vomiting, which often accompanies peptic ulcer disease, can intensify the symptoms of alkalosis. The intensity of carbon dioxide release in some cases leads to perforation of the walls of the gastrointestinal tract. In patients with cardiac or kidney disease, excessive Na+ intake can cause edema and heart failure. The drug “Sodium Bicarbonate” enhances the effect of antihypertensive drugs.

Dosage and method of administration

As a rule, the dosage regimen of this medication depends on the route of administration and indications. If the medicine is taken orally, then for adults the standard dose is 0.5-1 grams several times a day. For children - 0.1-0.75 grams (depending on age) per dose. In suppositories, the drug is prescribed in dosages of 300, 500 and 700 mg. In the form of injections and drips, the medicine is used against sea and airborne diseases. Moreover, one injection accounts for 140-180 ml (4% solution). For severe forms of seasickness, 5-7 injections are given, for moderate illness - 3 or 4 pcs. To prevent symptoms, 14-20 days before a sea voyage, people prone to motion sickness are given 3 or 4 injections in the dosages indicated above. The interval between injections is three days. For conjunctivitis, laryngitis, rhinitis, stomatitis, sodium bicarbonate is used in the form of a rinse (in pure form or in combination with other drugs). For inhalation, aqueous solutions (0.5-2%) are used. They are also used for washing the skin, upper respiratory tract, mucous membranes when toxic, irritating substances, as well as strong acids (sulfuric, nitric, hydrochloric, etc.) come into contact with them. For acidosis, aqueous solutions (1-5%) are administered intravenously (drip) in an amount of 50-100 ml. You can also deliver the medication using drip enemas (4%).

Additional Information

All information in this article is presented for informational purposes only. It is highly not recommended to use it and the medication without first consulting a doctor. It should be understood that self-medication is dangerous and can cause harm to health.

Structural formula

Russian name

Latin name of the substance: Sodium bicarbonate

sodium hydrocarbonas ( genus. sodium hydrocarbonatis)

Gross formula

C-H-O3Na

Pharmacological group of the substance Sodium bicarbonate

Nosological classification (ICD-10)

CAS code

144-55-8

Characteristics of the substance Sodium bicarbonate

White crystalline powder, odorless, salty-alkaline taste. Stable in dry air, slowly decomposes in humid air. Easily soluble in water (1:2) to form alkaline solutions (pH of 5% solution 8.1), practically insoluble in ethanol. Molecular weight 84.01.

Pharmacology

pharmachologic effect- expectorant, antacid, mucolytic, restoring the alkaline state of the blood.

In the stomach, when taken orally, it interacts with hydrochloric acid of gastric juice and causes its neutralization. Reduces the acidity of gastric juice, relieves pain from peptic ulcers of the stomach and duodenum. The antacid effect develops quickly, but is short-lived. The carbon dioxide formed in the neutralization reaction causes discomfort in the stomach (due to its distension) and belching, and also excites the receptors of the gastric mucosa, enhances the release of gastrin with secondary activation of secretion. Excessive release of carbon dioxide during gastric ulcer can provoke perforation of the gastric wall. For this reason, in case of poisoning with acids, sodium bicarbonate is not used for neutralization.

When taken orally, it is quickly absorbed. Sodium and carbonic acid ions are included in the metabolic cycle. Once absorbed into the blood, it shifts acid-base balance towards alkalosis, promotes the release of sodium and chlorine ions, increases osmotic diuresis, and alkalinizes urine (prevents the precipitation of uric acid salts in the urinary system). It should be taken into account that with vomiting that accompanies a peptic ulcer, chlorides are lost and alkalosis is enhanced due to hypochloremia. It shifts the reaction of bronchial mucus to the alkaline side, helps to thin sputum, and improves expectoration. Relieves symptoms of sea and air sickness.

A shift in acid-base balance towards alkalosis during the usual short-term course of treatment is not accompanied by clinical symptoms, but in case of renal failure it can significantly worsen the condition. In patients with concomitant heart or kidney diseases, excess sodium intake causes edema and heart failure.

There is information about the possibility of use for the prevention and treatment of kinetosis (iv, rectally).

Application of the substance Sodium bicarbonate

Increased acidity of gastric juice, peptic ulcer of the stomach and duodenum, metabolic acidosis (including during infections, intoxications, diabetes mellitus, in the postoperative period), the need to dilute bronchial secretions, inflammatory diseases of the eyes, oral cavity, mucous membranes of the upper respiratory tract (including when irritated by acids); to loosen earwax; relief of discomfort from mild urinary tract infections, alkalinization of urine; renal tubular acidosis, urate kidney stones, cystine kidney stones.

Contraindications

Hypersensitivity; conditions accompanied by the development of alkalosis; hypocalcemia (increases the risk of alkalosis and the development of tetanic convulsions), hypochloremia (loss of Cl -, including those caused by vomiting or prolonged decreased absorption in the gastrointestinal tract, can lead to severe alkalosis).

Restrictions on use

Edema, arterial hypertension (the condition may worsen), anuria or oliguria (increases the risk of excessive sodium retention).

Use during pregnancy and breastfeeding

It is necessary to compare the risk and benefit, because sodium bicarbonate can cause systemic alkalosis.

It is not known whether sodium bicarbonate passes into breast milk.

Side effects of the substance Sodium bicarbonate

With long-term use - alkalosis and its clinical manifestations: loss of appetite, nausea, vomiting, abdominal pain, anxiety, headache, in severe cases - tetanic convulsions; possible increase in blood pressure; when using suppositories - a laxative effect, urge to defecate, diarrhea, flatulence, rumbling.

Interaction

Combine with quinidine and sympathomimetics with caution.

Overdose

Updating information

Overdose

Symptoms: If the dose of sodium bicarbonate in the form of a solution for infusion is exceeded, the development of decompensated alkalosis and tetanic convulsions is possible.

Treatment: if alkalosis develops, stop intravenous administration of the drug; if there is a risk of developing convulsions, calcium gluconate is administered intravenously.

The powder for preparing solutions is a pure substance, sodium bicarbonate.

In the solution for infusion therapy, the active substance is present at a concentration of 50 g/l.

Optimize the absorption and effects of sodium bicarbonate, disodium edetate dihydrate and water for injection.

Release form

Powder for preparing a solution for infusion therapy. In bags of 50 g.

Powder for the preparation of a solution for topical use and oral administration. In bags of 10, 25 and 50 g.

Solution for infusion 4%. Available in 2 and 5 ml in disposable containers made of polymer materials; 100, 200 and 400 ml bottles; 100 and 250 ml in polymer containers.

Tablets 0.3 and 0.5 g.

Suppositories for rectal use 0.3, 0.5 and 0.7 g, 10 suppositories per package.

pharmachologic effect

A remedy for the treatment of acid-related diseases. Has an antacid effect and stimulates expectoration.

Pharmacodynamics and pharmacokinetics

Helps restore the disturbed balance of water and electrolytes, as well as acid-base balance.

During the dissociation (in chemistry and biochemistry - the reversible decomposition of complex substances into individual elements and/or constituent components) of sodium bicarbonate, the bicarbonate anion is released. It binds hydrogen ions, resulting in the formation of a carboxylic acid, which subsequently breaks down into water and carbon dioxide (released during respiration).

This causes an alkaline shift and an increase in the buffer capacity of the blood.

Sodium bicarbonate increases osmotic diuresis and excretion of Na and Cl ions from the body, reduces the acidity of urine, and prevents the sedimentation of uric acid in the urinary system.

Bicarbonate anion does not penetrate into the intracellular space.

The pharmacokinetic profile of the drug has not been studied.

Indications for use: what does baking soda treat?

Use in medicine is indicated for diseases that are accompanied by an increase in the acidity of digestive juice in the stomach, , metabolic acidosis (including when which develops in the postoperative period or against the background , infectious disease , intoxication ).

Treatment with the drug is used for inflammatory ophthalmological diseases , and also when inflammatory diseases of the mucous membranes of the upper respiratory tract and oral cavity .

The medicinal properties of baking soda are used in cases where there is a need to loosen earwax and liquefy secretion of bronchial glands , to alkalinize urine and reduce discomfort during mild urinary tract infections , at tubular (canalicular) renal acidosis .

Sodium bicarbonate is also used in therapy that aims to remove cystine And urate kidney stones .

Contraindications

Contraindications for treatment with baking soda:

• hypersensitivity;
• conditions that are accompanied by the development alkalosis .

In addition, contraindications for use are hypochloremia And hypocalcemia . In the first case, taking sodium bicarbonate can provoke a long-term decrease in absorption in the digestive canal and vomiting, which in turn leads to a significant loss of chlorine ions by the body, including severe alkalosis .

Taking soda when hypocalcemia may be accompanied by tetanic seizures and increased risk alkalosis .

Side effects

Long-term use of sodium bicarbonate leads to alkalosis (increased blood pH), the clinical manifestations of which are:

• nausea;
• vomit;
• deterioration of appetite (to the point of complete loss);
• stomach ache;
• tetanic convulsions (in especially severe cases);
• increase in blood pressure.

When using suppositories, a laxative effect may develop, the urge to defecate, rumbling, And .

Sodium bicarbonate: instructions for use

Instructions for use of sodium bicarbonate powder

Sodium bicarbonate powder is used to prepare aqueous solutions for washing, rinsing and inhalation use.

Treating Cancer with Baking Soda: Sodium Bacarbonate Against Cancer

Tullio Simoncini (a doctor from Italy) believes that cancer is nothing more than a greatly overgrown colony of fungi of the genus Candida, and the traditional interpretation of the nature of the disease is fundamentally incorrect.

Following this theory, it can be assumed that the fungus, which is usually well controlled by the immune system of a healthy person, begins to actively multiply in a weakened body, forming a large colony.

When an organ becomes infected thrush , the immune system reacts to it by building a protective barrier from the body's cells. Metastasis can be explained by further growth of the colony and migration of the fungus in the body.

Only cells of a normally functioning immune system can destroy the fungus. Thus, the key to recovery is a strong immune system.

The reason for decreased immunity and, consequently, the occurrence of many serious diseases is a decrease in pH. If we talk about oncological diseases , then the optimal environment for their development is an acidic environment, that is, an environment in which the pH value does not exceed 5.41.

In a newborn child, for comparison, it is 7.41, and in a healthy adult it should range from 7.3 to 7.4.

The recommendations in the Physician's Handbook, dated 1973, indicate that patients with a pH of 7.25 or lower should be prescribed alkalizing therapy, or, in other words, they are recommended to take from 5 to 40 grams of soda per day.

Soda restores intracellular metabolism , prevents potassium loss and enhances oxygen absorption.

Sodium bicarbonate for the treatment of cancer is taken on an empty stomach, half an hour before meals, starting with a volume equal to a fifth of a teaspoon, and gradually increasing the dose by 2-3 times.

A single dose is diluted in 200 ml of hot milk (very warm water) or washed down with the same amount of water/milk. You need to take the “medicine” 2 or 3 times a day.

Overdose

If the recommended instructions are exceeded, the development of hyperalkalosis And tetanic convulsions . During development hyperalkalosis you should stop administering the drug. If there is a risk of developing tetany , the patient is prescribed 1-3 grams of calcium salt of gluconic acid ( ).

Interaction

Under the influence of sodium bicarbonate, urine pH increases, which leads to:

• decreased excretion amphetamine ;
• reduced toxicity and increased excretion ;
• delayed excretion from the body and an increased risk of developing side effects associated with its use - sleep disturbances, increased anxiety, , .

When using a maintenance dose, sodium bicarbonate helps to reduce the plasma concentration of lithium, which is due to the influence of Na ions.

The drug helps reduce absorption tetracyclines when taken orally.

A solution for infusion when administered by drip into a vein can enhance the antihypertensive effect .

The solution reacts with acids ( ascorbic, nicotine etc.), alkaloids (caffeine, , apomorphine , ), calcium salts, heavy metals (copper, zinc, iron), magnesium, cardiac glycosides , which is accompanied by precipitation or hydrolysis (decomposition) of organic compounds. Therefore, these substances should not be dissolved in sodium bicarbonate solution.

Also, do not mix sodium bicarbonate with solutions that contain phosphorus.

Terms of sale

All dosage forms of Sodium bicarbonate, with the exception of the solution for infusion therapy, are over-the-counter products.

Storage conditions

The optimal temperature for storing sodium bicarbonate is 15-30°C.

Best before date

special instructions

What is sodium bicarbonate? All about baking soda

Everyone knows what soda is. It is a fine white crystalline powder with a specific salty-alkaline taste. According to Wikipedia, the substance is completely non-toxic to the human body, and is also explosion and fireproof.

The Pharmacopoeia states that the powder is stable in dry air, practically insoluble in 95% alcohol and highly soluble in water. Decomposes slowly when exposed to moisture.

If sodium bicarbonate is calcined, it loses weight. When the powder is calcined at a temperature of 280-300°C, its mass decreases by at least 36.6%.

The substance is known as sodium bicarbonate, baking (or drinking) soda, sodium bicarbonate (or bicarbonate). Baking soda is a pure substance and is an acid salt of sodium and carbonic acid (H2CO3).

Neutralizes acids (quite often there are instructions like “hydrochloric or nitric acid was neutralized with soda”).

The chemical formula of baking soda (or, in other words, the formula of sodium bicarbonate) is NaHCO3. The rational formula of sodium bicarbonate is CHO3Na.

The name of the substance in Latin is Sodium bicarbonate (Sodium hydrogen carbonate).

Sodium bicarbonate is produced in accordance with GOST 2156 76. The standard is valid and applies to the product that is produced for the needs of the chemical, light, food, pharmaceutical and medical industries, retail trade and non-ferrous metallurgy.

Are soda ash and baking soda the same thing? Soda ash - what is it?

Sodium bicarbonate and soda ash are two different products that should not be confused. What is soda ash? This is a substance with the chemical formula Na2CO3. Its main difference from sodium bicarbonate is the degree of alkaline activity.

If sodium bicarbonate is a weak alkali with a pH value of 8.1, then soda ash exhibits strong basic properties (its pH value is 11).

In the All-Russian Classifier of Products, baking soda and soda ash are assigned different OKPD codes.

Soda ash is used for household needs: softening water, cleaning dishes, tiles, washing floors, clearing pipe blockages, preventing scale formation, etc.

Healing properties, benefits and harms of baking soda

The areas of application of sodium bicarbonate are quite diverse. It is used to prevent strokes, treat cancer and a number of other serious diseases, alcoholism, tobacco and any other types of addiction (including toxic and narcotic substances), to remove harmful substances and toxins from the body, and for hair care.

Soda destroys acidosis and provokes an alkaline shift, which is accompanied by alkalization of digestive juices, dissociation of water contained in the body into OH- and H+ ions due to amino acids, enzymes, amine alkalis, D- and RNA nucleotides and general improvement of the body.

In an alkaline environment, biochemical activity increases significantly , , vitamin PP , pyridoxine ,cobamide .

With increased acidity, saliva also becomes acidic, which is why a person’s tooth enamel gradually begins to deteriorate. Therefore, for treatment and alkalization of saliva, the use of fluoride-containing pastes is supplemented with the use of soda.

A teaspoon of baking soda diluted in a glass of water is a well-known remedy for heartburn. Sodium bicarbonate is also used for the face: adding a pinch of soda every day to the foam or gel for washing, you can thoroughly cleanse the skin of blackheads and a layer of keratinized surface cells, relieve inflammation and get rid of acne.

A mask made from oatmeal (1 cup) and baking soda (1 teaspoon) ground into powder helps very well with rashes. Mix the ingredients well and pour into a glass jar. To prepare the mask, pour a tablespoon of the mixture with water to make a paste. The mass is applied to the face for 15-25 minutes.

The big advantage of the product is that it has no contraindications and is suitable for all skin types.

Baking soda is used for insect bites, sunburn, , bad breath and foot odor, diaper rash, and colds.

Large doses of soda are not absorbed with water and cause diarrhea, which makes it possible to use sodium bicarbonate as a mild laxative.

Knowing everything about what baking soda is and how healthy it is, you should determine whether you can always drink it. So, when can sodium bicarbonate, instead of being beneficial, harm the body?

The drug is dangerous in case of any concomitant diseases of the kidneys and heart, individual intolerance, as well as if it comes into contact with the mucous membrane of the eyes.

When taken systematically, carbon dioxide begins to be released in the stomach, which has a stimulating effect on the receptors of the gastric mucosa, stimulates the release of gastrin and can cause a secondary increase in secretion. Regular use also increases the risk of phosphate stone formation.

The removal of carbon dioxide can cause perforation of the walls of the digestive canal.

What are the benefits of drinking soda in everyday life?

In everyday life, sodium bicarbonate is used in baking bakery and confectionery products, to retain unpleasant odors in the cat's litter box, to clean the trash can from dirt and odors, to wash tiles, wallpaper and bathroom fixtures, to wash hands after working with strong-smelling products (onions, garlic, etc.). d.), speeding up the cooking of legumes, as a remedy for ants.

How to clean your heels with baking soda? What are soda foot baths made from?

Baking soda is often used to soften heels and eliminate unpleasant foot odor. To prepare a bath, add a tablespoon of sodium bicarbonate and a couple of drops of any essential oil to a liter of warm water. Keep your feet in water for 15 minutes (it’s better to take a bath at night).

After the skin has softened, it should be carefully treated with pumice. Then the feet are rinsed with water and lubricated with a rich cream, and socks are put on top.

You can use warm milk instead of water.

To prepare a foot scrub, you can mix 1 teaspoon of vegetable oil (for example, olive) with a tablespoon of soda, or you can simply dilute the soda with water to a paste. The mixture is applied to the skin and massaged well to remove rough skin.

Helena Roerich about baking soda

Roerich E.I. (Russian religious philosopher, public figure and writer) considered the healing properties of baking soda to be so strong that regular use of this simple and affordable remedy twice a day can prevent many diseases, including cancer.

When under severe stress, Elena Ivanovna herself took up to 8 coffee spoons of baking soda per day, pouring them onto her tongue and washing it down with water. She advised children to dilute soda in hot milk. This recipe in folk medicine is often used to treat colds that are accompanied by a severe cough.

Hot milk and soda, brought almost to a boil, relieves not only pain and inflammation in the throat, but also body aches.

Drinking baking soda is the easiest and most natural method to solve the problem of constipation. In addition, the substance neutralizes toxic substances well.

In the works of E.I. Roerich also mentions the treatment of cancer with sodium bicarbonate. The author points out that soda is an important component of human blood. She is present in plasma And lymphoplasm , in which they are located . Presumably, soda is necessary for energy nutrition lymphocytes - cells that are responsible for the body's immune response.

Precautionary measures

When signs appear alkalosis you should take a break from treatment. If the drug is used for correction acidosis , the ASR indicators should be kept under control.

Analogs

Synonyms are drugs Soda Buffer And Sodium bicarbonate . Level 4 ATC code is the same as Glyuksilom , , , Xylate , Lactoxyl , , , Plerigo , .

Lose weight with baking soda. The benefits and harms of baking soda

Baking soda for weight loss is used to change acidity in the body, normalize digestion and facilitate a number of other physiological processes, as well as reduce appetite.

The recipe for baking soda for weight loss is as follows: freshly squeezed juice of 3 lemons and 1 tbsp. spoon of sodium bicarbonate per liter of water.

The danger of using baking soda for weight loss is that systematically taking sodium bicarbonate solution can provoke the occurrence of a number of diseases of the digestive system (or aggravate existing diseases).

A safer recipe for losing weight is soda baths. Sodium bicarbonate in hot water (36-37°C) stimulates the opening of pores and the removal of toxins, due to which the body is freed from excess weight and reduces its volume.

To prepare a 150-200 liter bath, dilute 200 g of soda in a small volume of very hot water.

Even if such a procedure does not radically solve the problem of excess weight, its benefits for the body will be enormous, since it will cleanse lymphatic system , reduce manifestations cellulite (especially if you add essential oils to the water), improve skin condition and strengthen the nervous system.

During pregnancy

There is no data that soda is contraindicated during pregnancy and lactation, but in these cases the drug must be administered with caution and under the control of the blood hormone.

It is not known whether sodium bicarbonate can pass into milk. According to the FDA classification, it belongs to category C.