Curantyl for pregnant women than can be replaced. Visitor survey results

Curantil is a drug that is dispensed from a pharmacy only by prescription, its cheap Russian and foreign counterparts, for the most part, too.

This article is not intended for you to replace your own doctor's prescription, it is for informational purposes and compares prices for Curantil and its synonyms and analogues, drugs with a similar effect!

Only a doctor can replace a drug, especially one as serious as Curantil, who will select an analogue not only taking into account the patient’s economic capabilities, but also after carefully studying the medical history. It is important to remember that even the same composition does not guarantee that the analogues will suit the patient.

Curantil: cheap analogues

In principle, Curantil has only one analogue, or rather, even a synonym, that is, a drug that absolutely and completely corresponds to Curantil itself in all respects. This is dipyridamole. Dipyridamole is produced by domestic manufacturers at a dosage of 25 and 75 mg per 1 tablet. Let's try to figure out why doctors prescribe this remedy and how the analogues differ from the original.

Curantyl and Dipyridamole: twin brothers

Despite the fact that the active ingredient in both drugs is dipyridamole at a dosage of 25 or 75 mg, patients, especially those prone to allergies, should be aware that auxiliary components may still differ slightly depending on the manufacturer. Therefore, in the presence of individual hypersensitivity reactions, the replacement of Curantyl with an analogue may not be suitable for such a patient.

Of course, Curantil will cost much more than its Russian-made counterparts. If Dipyridamole 25 mg in a package containing 100 tablets costs about 370 rubles ($ 6), then a similar package of Curantyl is already 580 rubles ($ 7.5).

Your doctor may also recommend other medications to replace. They are not synonymous with Curantyl and are not analogues, however, they can be used in the treatment of the same diseases as Curantyl due to its antiplatelet (antithrombotic) effect. Let's try to dwell on them in more detail.

There are many drugs with similar effects, ranging from the well-known pentoxifylline and xanthinol nicotinate to new drugs such as clopidogrel, but they are all available by prescription and
we will not focus on them.

From over-the-counter drugs, an analogue of chimes is aspirin and its derivatives and several herbal preparations.

Acetylsalicylic acid or well-respected Aspirin

Yes - yes, aspirin can not only lower the temperature and eliminate headaches, but also reduce blood viscosity. That is why he, like other analogues, can replace Curantil with such a medical indication. To thin the blood, regular intake of aspirin in reduced doses is used. By the way, most patients do not know that Aspirin has a wide range of contraindications and an even more extensive list of adverse symptoms. Without medical advice, its frequent use can greatly undermine health, even death. For comparison, Curantil is much better tolerated than acetylsalicylic acid and does not have such a harmful effect on the mucous membranes of the gastrointestinal tract. The price of the drug is cheap. For 10 tablets
you have to pay 6 rubles.

ATTENTION! Even the legendary and over-the-counter aspirin sometimes has fatal complications, especially in children (Reye's syndrome)!

Ginkgo biloba

ginkgo Biloba- herbal non-prescription drug according to the classification is classified in the group of analogues of chimes.

Ginkgo Biloba - a plant with anti-aggregation properties, is part of many combined food supplements, and is also used as an independent drug. It is very popular in the Russian pharmaceutical market, but in the USA it is not approved as a medicine.

Preparations based on Ginkgo Biloba have a very large range of prices, from 120 rubles ($ 2) to 1600 rubles ($ 25), it depends on the manufacturers and the number of tablets in the package.

There are no side effects as such, except for an allergy to the plant itself.

Fish fat

Also in the Russian Pharmacopoeia in the group of analogues of chimes is Eikonol- sold as
edible oil or in capsules, the active ingredient is Omega 3 triglycerides derived from fish oil. Omega-3 triglycerides have a wide range of prices. If omega 3 triglycerides are purchased in the form of fish oil, it can be very inexpensive, sold as an edible oil. Unlike Ginkgo Biloba, fish oil is registered as a heart medicine in the US.

Attention! Fish oil has contraindications!

Is it possible to replace chimes with fish oil?

Such a statement of the question is possible only in the office of your attending physician, who bears full responsibility for the result. Both Curantyl and its analogues, cheap or not, are often used in the treatment of serious diseases when the patient's condition approaches critical.

Regardless of your knowledge, the drug Curantyl and its main synonyms, and medicines analogues require a medical prescription. Please contact your doctor for more information.

In this article, you can read the instructions for using the drug Curantyl. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Curantyl in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Curantyl in the presence of existing structural analogues. Use for the treatment of circulatory disorders and the prevention of thrombosis in adults, children, as well as during pregnancy and lactation. Composition and contraindications of the drug.

Curantyl- myotropic vasodilator. It has an inhibitory effect on platelet aggregation, improves microcirculation.

Dipyridamole (the active ingredient of Curantil) dilates arterioles in the coronary circulation system, when taken in high doses, in other parts of the circulatory system. However, unlike organic nitrates and calcium antagonists, expansion of larger coronary vessels does not occur.

The vasodilating effect of dipyridamole is due to two different mechanisms of inhibition: inhibition of adenosine uptake and inhibition of phosphodiesterase.

In vivo, adenosine is found at a concentration of approximately 0.15-0.20 µmol. This level is maintained due to the dynamic balance between ejection and recapture. Dipyridamole inhibits the uptake of adenosine by endothelial cells, erythrocytes and platelets. After the introduction of Curantyl, an increase in the concentration of adenosine in the blood and an increase in vasodilation caused by adenosine are detected. At higher doses, inhibition of platelet aggregation caused by adenosine occurs, and the tendency to thrombosis decreases.

The breakdown of cAMP and cGMP, which inhibit platelet aggregation, occurs in platelets under the action of the corresponding phosphodiesterases. At high concentrations, dipyridamole inhibits both phosphodiesterases, at therapeutic concentrations in the blood, only cGMP-phosphodiesterase. As a result of stimulation of the corresponding cyclases, the power of cAMP synthesis increases.

As a pyrimidine derivative, dipyridamole is an interferon inducer and has a modulating effect on the functional activity of the interferon system, increases the reduced production of interferon alpha and gamma by blood leukocytes. The drug increases nonspecific resistance to viral infections.

Compound

Dipyridamole + excipients.

Pharmacokinetics

Dipyridamole is almost completely bound to plasma proteins. Dipyridamole accumulates in the heart and in red blood cells. Dipyridamole is metabolized in the liver by binding to glucuronic acid. It is excreted in the bile as a monoglucuronide.

Indications

treatment and prevention of cerebrovascular accidents by ischemic type;
encephalopathy;
primary and secondary prevention of coronary artery disease, especially with intolerance to acetylsalicylic acid;
prevention of arterial and venous thromboses and treatment of their complications;
prevention of thromboembolism after heart valve replacement surgery;
prevention of placental insufficiency in complicated pregnancy;
when planning a pregnancy;
microcirculation disorders of any type (as part of complex therapy);
prevention and treatment of influenza, ARVI (as an interferon inducer and immunomodulator) - for taking the drug at a dose of 25 mg.

Release forms

Film-coated tablets 25 mg.

Coated tablets N 25 (25 mg).

Coated tablets N 75 (75 mg).

Instructions for use and dosage

The dose of the drug is selected depending on the severity of the disease and the individual response of the patient.

For the prevention and treatment of disorders of cerebral circulation, as well as for prevention, 75 mg is prescribed 3-6 times a day. The maximum daily dose is 450 mg.

To reduce platelet aggregation, Curantyl is prescribed at a dose of 75-225 mg per day in divided doses. In severe cases, the dose may be increased to 600 mg per day.

For the prevention of influenza and SARS, especially during epidemics, Curantil N25 and Curantil 25 are prescribed 50 mg (2 tablets or 2 tablets) per day in 1 dose. The drug is taken once a week for 4-5 weeks.

To prevent recurrence of acute respiratory viral infections in patients with frequent respiratory viral infections, Curantil N25 and Curantil 25 are prescribed 100 mg per day (2 tablets or dragees 2 times a day with an interval between doses of 2 hours). The drug is taken once a week for 8-10 weeks.

Tablets should be taken on an empty stomach, without breaking or biting, with a small amount of liquid. The duration of the course of treatment is determined by the doctor.

Side effect

heartbeat;
tachycardia (especially with the simultaneous use of other vasodilators);
bradycardia;
flushes of blood to the face;
flushing of the skin of the face;
coronary steal syndrome (when using the drug at a dose of more than 225 mg per day);
decrease in blood pressure;
nausea, vomiting;
diarrhea;
pain in the epigastric region;
thrombocytopenia, changes in the functional properties of platelets;
bleeding;
increased bleeding during or after surgery;
dizziness;
noise in the head;
headache;
skin rash;
hives;
weakness;
feeling of fullness in the ear;
myalgia;
rhinitis.

Contraindications

acute myocardial infarction;
unstable angina;
widespread stenosing atherosclerosis of the coronary arteries;
subaortic stenosis of the aorta;
heart failure in the stage of decompensation;
arterial hypotension;
collapse;
severe arterial hypertension;
severe cardiac arrhythmias;
chronic obstructive pulmonary disease;
chronic renal failure;
liver failure;
hemorrhagic diathesis;
diseases with an increased risk of bleeding (including peptic ulcer of the stomach and duodenum);
hypersensitivity to the components of the drug.

Use during pregnancy and lactation

It is possible to use the drug during pregnancy according to indications.

The use of the drug during lactation is possible only if the expected benefit of treatment outweighs the possible risk.

Use in children

special instructions

With the simultaneous use of tea or coffee (contain xanthine derivatives), the vasodilating effect of Curantyl may decrease.

Influence on the ability to drive vehicles and control mechanisms

Caution should be exercised when driving vehicles and operating mechanisms, since as a result of a drop in blood pressure while taking Curantyl, the ability to concentrate and speed of psychomotor reactions may worsen.

drug interaction

With the simultaneous use of Curantyl with anticoagulants or acetylsalicylic acid, the antithrombotic effect of the latter increases and, accordingly, the risk of developing hemorrhagic complications.

With the simultaneous use of Curantil enhances the effect of antihypertensive drugs.

When used together, Curantil may weaken the anticholinergic effects of cholinesterase inhibitors.

With simultaneous use, xanthine derivatives weaken the vasodilating effect of Curantyl.

Analogues of the drug Curantil

Structural analogs of the active substance.

During pregnancy, every woman should be careful about taking medications. In the next article, we will take a closer look at why doctors prescribe chimes during pregnancy.

Curantyl during pregnancy

Pregnancy is a celebration of life, a sea of unforgettable sensations and a great joy for parents who are looking forward to the birth of a child. The responsibility for a small life falls on a woman from the moment of conception and continues not only throughout pregnancy, but throughout life. Therefore, it is very important to monitor your health, change your habitual lifestyle, eat well, and of course, visit a gynecologist who will monitor the growth, development of the fetus and the pregnancy itself.

Given the modern pace of life, poor ecology, inadequate food quality, many pregnant women face a number of problems that can negatively affect the health of the fetus or the woman herself. Unfortunately, with the development of disorders in the body of a pregnant woman, it is difficult to do without drug treatment. Drug correction of pregnancy pathologies and their preventive measures are gaining more and more momentum, and it no longer surprises anyone that an outwardly healthy woman swallows various pills in order to maintain a long-awaited pregnancy.

One of the frequently prescribed drugs during pregnancy is "Kurantil", which helps to improve blood flow to the placenta, reduce the risk of developing fetal hypoxia, and prevent dystrophic changes in the placenta that can lead to premature birth or death of the fetus.

Future mothers do not always agree to take pills, as many believe that any medication during pregnancy is harmful. However, many obstetricians and gynecologists strongly recommend taking Curantil. What is this drug, how does it work, does it have contraindications and should it be used during pregnancy? Let's try to answer these questions, but it is worth noting that only a doctor can prescribe "Kurantil", and before use, you should read the instructions for the drug.

Often expectant mothers refuse to take prescribed medications.

What is the effect of Curantyl

"Kurantil" is a drug from the group of antiplatelet agents and immunomodulators, which improves blood microcirculation, supplying the cells of the body with necessary and useful waste products through small vessels. The active substance of the drug is dipyridamole - which has a vasodilatory myotropic effect, improves immunity, prevents the formation of blood clots, stimulates the formation of interferon, protects the body of a pregnant woman from the invasion of pathogenic viruses.

The formation of blood clots is observed with multicellular adhesion of aggregation cells, which provoke blockage of blood vessels, blocking the access of blood to individual organs, including the placenta. In pregnant women, vascular disorders requiring the use of "Kurantil" may develop due to metabolic disorders, hormonal imbalance, high blood cholesterol, concomitant diseases of the cardiovascular system, and other pathologies or anomalies of the body.

"Kurantil" during pregnancy allows you to relax the walls of blood vessels, eliminate blockages, improve blood circulation to the placenta, as a result of which a sufficient amount of oxygen and nutrients will be supplied to the fetus for full growth and development. Taking this drug helps prevent the development of severe toxicosis (preeclampsia of pregnancy) in the second trimester of pregnancy, increase the mother's resistance to viral infections.

In addition, taking "Kurantil" by pregnant women improves blood circulation not only in the placenta, but also in the uterus, kidneys and other organs and systems. The main immunomodulatory mechanism of "Kurantil" is that it promotes the production of interferon (blood protein), which has an antiviral and antitumor effect. The activity of interferon production increases immunity, which is extremely necessary during pregnancy, since viral diseases can cause severe complications that violate the condition of the mother and fetus.

Curantyl during pregnancy: indications

During pregnancy, all the internal organs of a woman work in an enhanced mode and need nutrition and oxygen. High aggregation of blood cells in the body of a pregnant woman can lead to serious complications that adversely affect the body of the future mother and fetus.

Complete or partial blockage of the vessels of the placenta leads to fetal hypoxia (lack of oxygen), preeclampsia (prolonged toxicosis), vasospasm, edema and other severe disorders. "Kurantil" for pregnant women is prescribed for the treatment and prevention of the following diseases or disorders:

Violation of cerebral circulation, encephalopathy;

Violation of placental circulation;

Prevention of hypoxia and intrauterine growth retardation;

Varicose veins, thrombophlebitis, thrombosis;

Violation of the microcirculation of small vessels in complex therapy with other drugs;

Premature aging of the placenta;

Fetoplacental insufficiency, preeclampsia, fetal hypotrophy;

Spasm of blood vessels, convulsions;

Prevention and treatment of viral infections;

Hypercoagulability (increased blood clotting);

Pathologies of the cardiovascular system: angina pectoris, heart failure, arterial hypotension or hypertension;

kidney failure;

Decreased immunity.

Curantyl will provide oxygen to the fetus

In addition, "Kurantil" will save a woman from swelling of the limbs, headaches, and normalize the work of the heart. Also, this drug increases the production and activity of interferon, which allows you to increase immunity and protect a woman from viral and infectious diseases. The advantage of the drug is the fact that it has a positive effect only on the placenta and does not affect the fetus in any way. After taking the drug, it does not linger in the body, it is broken down in the liver and excreted in the bile.

Contraindications, side effects Curantyl

Like any other drug, "Kurantil" has a number of contraindications:

hypersensitivity to the composition of the drug;

diseases with the development of bleeding;

hemorrhagic diathesis;

severe arrhythmias;

tonic atherosclerosis of the coronary arteries;

arterial hypotension and other diseases of the heart, blood vessels.

Usually "Kurantil" is well tolerated, only in rare cases, nausea, vomiting, dizziness, general weakness of the body and other symptoms may occur:

redness of the skin of the face;

tachycardia and bradycardia.

abdominal pain, diarrhea, vomiting, nausea;

noise in the head, headache;

allergic reactions: itching, urticaria, rash;

increased weakness, drowsiness.

In cases of an overdose of the drug, the symptoms of side effects increase, in which case it is urgent to rinse the stomach and seek medical help.

At what time is Curantyl prescribed

"Kurantil" is prescribed at different stages of pregnancy. In some cases, this remedy is used by a woman for 9 months, with short short breaks. In addition, many obstetricians and gynecologists recommend using the drug at the planning stage of conception. With premature aging of the placenta, "Kurantil" is prescribed in the last months of pregnancy.

"Kurantil" does not have a harmful effect on the fetus, but only improves the condition of the expectant mother and baby, increases resistance to infections that are certainly not needed during pregnancy, improves blood circulation and nourishes the cells of the body with useful and nutritious substances.

What can replace "Kurantil" during pregnancy?

If there are doubts about Curantil, or a woman has side effects, the doctor may prescribe another drug - an analogue. There are several analogues of "Kurantil", they all have the same mechanism of action, composition, indications, they are only produced by other technologies of different pharmaceutical companies.

The analogues of "Kurantil" include: "Dipyridamole", "Parsedil", "Persantin" and others, which are produced by domestic or foreign manufacturers. You can use analogues of the drug only after consultation with your doctor.

During pregnancy, it is worth following all the recommendations of a gynecologist or obstetrician, on which the health of the unborn child often depends. Do not forget about the right lifestyle, proper nutrition and other important factors that will only have a positive effect on the child and the pregnancy itself.

Curantil is a powerful myotropic agent that dilates blood vessels and provides active blood circulation, and therefore, the medication is used for cerebrovascular accidents, thrombosis and. Also, the drug promotes the production of interferon, therefore it is used as an immunomodulator in the prevention of diseases of a viral nature - influenza and SARS.

Features of the drug Curantil

The main active ingredient of the drug is dipyridamole. From the content in the composition of the drug Curantyl active substance in the amount of 25, 50, 75 or 100 mg, the drug is called:

Curantyl 25;
Curantyl 50;
Curantyl 75;
Curantyl 100.

It is from the dosage in the preparation of dipyridamole that its purpose depends. So, in order to prevent and treat cerebral circulation, as well as to reduce platelet aggregation, Curantyl 75 is prescribed, as a rule, during influenza and SARS epidemics, Curantyl 25 is indicated.

What can replace Curantyl?

The drug Curantil has analogues for the active substance. The most famous analogues of Curantil tablets are drugs produced by different pharmaceutical companies:

Agrenox;
Dipyridamole;
Persanthin;
Parsedyl;
Sanomil-Sanovel;
Trombone.

There are no structural differences between the drugs, and the difference lies in the form of release and cost. It should be borne in mind that the higher the dosage of the active substance in the drug, the higher its cost. Thus, a package of Curantyl 25 out of 120 tablets costs 4.5 USD, while the cost of Curantyl 75 manufactured by Berlin-Chemie (Germany) in retail sales is 12-16 USD.

Persanthin

An analogue of the drug Curantil 75 is an injection solution Persantin. This drug is administered intravenously and quickly enters the bloodstream, in connection with which Persantin is used as a vasodilator drug (expanding the lumen of the coronary vessels) for obliterating arterial diseases of the extremities and as a therapeutic (prophylactic) agent for thrombosis, thromboembolism. The cost of the drug is approximately 4.5 USD.

Trombone

Another generic - Trombonil is available in the form of coated tablets, dragees and injections. Thrombonil dilates coronary vessels, increasing blood flow velocity, and reduces platelet adhesiveness, preventing the formation of blood clots. Experts note the special effectiveness of the pharmaceutical drug Trombonil in progressive atherosclerosis.

Agrenox

For the treatment and prevention of ischemic stroke, doctors recommend taking an analogue of Curantyl - Agrenox. According to medical studies, the drug reduces the risk of stroke by 37%. Agrenox is sold in pharmacies in capsule form. Hard gelatin capsules are packaged in tubes of 30 and 60 pieces. Agrenox costs an average of 20 USD.

Dipyridamole

In order to prevent viral diseases, the most commonly used analogue of Curantyl 25 is the drug Dipyridamole. The drug, acting on interferons, strengthens the immune system, and, accordingly, the body better resists influenza and SARS. Dipyridamole is available in tablet and oral suspension form. As a prophylactic, it is recommended to take 6 teaspoons (300 mg) of the suspension per day. The cost of Dipyridamole is less than $2.

Curantyl and its analogues in therapy are quite popular due to their high effectiveness. It is also valuable that when taking these drugs, side effects are observed relatively rarely, they can also be used during pregnancy with placental insufficiency, if the therapeutic effect outweighs the potential risk to the fetus.