Duphaston reception hours. Positive properties of Duphaston

Duphaston is a synthetic hormonal drug of the latest generation, which is an artificial analogue of the female hormone progesterone.

A unique feature of the drug lies in its chemical formula, which is almost identical to the structure of the natural hormone progesterone. It is necessary for the female body to ensure biological changes associated with the preparation for pregnancy and its normal course. The basis of the drug is the progestogen hormone - dydrogesterone. It acts directly on the uterine mucosa, which eliminates most of the side effects that accompany the use of other synthetic hormones.

On this page you will find all the information about Duphaston: complete instructions for use for this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Duphaston. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

The active ingredient of the drug dydrogesterone is an analogue of natural progesterone. Dufaston is a hormonal drug.

Terms of dispensing from pharmacies

Released by prescription.

Prices

How much does Duphaston cost? The average price in pharmacies is at the level of 480 rubles.

Release form and composition

Coated tablets, 10mg. 20 tablets in PVC/Al blister. 1 PVC / Al blister, together with instructions for use, is placed in a cardboard box.

• 1 coated tablet contains: active substance: dydrogesterone, 10 mg;
• Excipients: lactose monohydrate, hypromellose, corn starch, colloidal silicon dioxide, magnesium stearate;
• Sheath: Opadry white Y-1-7000 (hypromellose, polyethylene glycol 400, titanium dioxide (El 71)).

Round, biconvex, white, film-coated, beveled-edged tablet, scored on one side, engraved with an "S" above the "T" sign on one side of the tablet and "155" on the other side (on both sides of the notch).

Pharmacological effect

In terms of its molecular structure, pharmacological and chemical properties, dydrogesterone is close to natural progesterone. This element is not a derivative of testosterone, does not have side effects that are inherent in almost all synthetic progestogens, which are also called androgenic progestogens. Dydrogetestrone has no glucocorticoid, anabolic, androgenic, estrogenic, or thermogenic activity.

Duphaston according to the instructions is part of a complex HRT for menopause, the drug retains a beneficial effect on the blood lipid profile from estrogens. Unlike the estrogen hormones, which negatively affect the blood coagulation system, didrogestrone has no effect on the coagulation index. According to the instructions, the drug does not have a negative effect on the liver, carbohydrate metabolism when planning the conception.

When taken orally, dydrogesterone selectively acts on the endometrium, which helps prevent an increased risk of hyperplasia or carcinogenesis due to excess estrogen. The medication according to the instructions is indicated for endogenous progesterone deficiency. Dufaston does not have a contraceptive effect, because it is used when planning a pregnancy. The tool makes conception possible, ensures the preservation of pregnancy during therapy.

Indications for use

The use of Duphaston is indicated in cases where there is or is suspected a deficiency of endogenous progesterone, in cases where its positive effect has been clinically proven:

• infertility due to luteal insufficiency;
• threatened abortion;
• habitual abortion;
• premenstrual syndrome;
• dysmenorrhea;
• irregular cycle.

In addition, in combination with estrogen, Duphaston can be used for:

• secondary amenorrhea;
• dysfunctional uterine bleeding.

Contraindications

You can not take medication:

1. Lactase deficiency, galactose and glucose intolerance, malabsorption syndrome;
2. The period of breastfeeding;
3. Hypersensitivity to the components of the drug.

If the patient's history indicates itching during a previous pregnancy, Duphaston should be used with caution.

Use during pregnancy and lactation

According to the instructions, Duphaston is used during pregnancy according to indications.

Since dydrogesterone can be excreted in breast milk, if treatment with the drug is necessary, it is recommended to stop breastfeeding.

Instructions for use

The instructions for use indicate that Duphaston tablets are taken orally. The dosage of the drug should correspond to the diagnosis. Treatment is carried out only on prescription and under medical supervision.

1. Infertility caused by luteal insufficiency- appoint 1 tablet per day from the 14th to the 25th day of the cycle. The drug is taken for at least six months or 6 cycles. If conception has already occurred, then Duphaston should be taken further, as with a threat of abortion.
2. Endometriosis - dosage of 10 mg (1 tablet) 2 to 3 times a day. They start either from the 5th to the 25th day of the monthly cycle, or a permanent intake.
3. Habitual abortion - take 1 tablet 2 times a day. Treatment should be continued until the 20th week of pregnancy, then the dosage is gradually reduced.
4. Threatened abortion- take 40 mg (4 tablets) once. Then 1 tablet every 8 hours until the situation returns to normal. If the symptoms begin to increase again, then the dose of the drug should be increased again. Further, "Dufaston" should be taken until the 12-20th week of pregnancy.
5. Prolonged absence of menstruation (amenorrhea)- complex treatment - estrogen-containing drugs, 1 tablet per day, starting from the 1st day of the cycle. From the 11th day of the cycle, treatment is supplemented with Duphaston. These drugs should be taken until the 25th day of the cycle. Application is designed for at least 3 menstrual cycles.
6. Painful menstruation- 1 tablet 2 times a day. Application is indicated from the 5th to the 25th day of the cycle.
7. PMS - is prescribed 1 tablet 2 times a day. Treatment is carried out from the 11th to the 25th day of the cycle. The drug is prescribed for a period of 3 to 6 months.
8. Irregular monthly cycle- the drug is prescribed for 1 table. 2 times a day. "Dufaston" should be used from the 11th to the 25th day of the cycle.
9. Hormone Replacement Therapy- is prescribed in a pair with estrogens, 1 tablet 1 time per day for 2 weeks within a 28-day cycle. Usually the reception takes place in the last 14 days of the cycle. If the response to progesterone therapy is not detected by ultrasound and is not confirmed by tests, then the dose should be revised upwards.
10. Dysfunctional uterine bleeding- the dose is 1 tab. 2 times a day. The duration of treatment is from 5 to 7 days. As a prophylaxis of bleeding, the use of the drug is prescribed - 1 table. 2 times a day. Therapy is carried out from the 11th to the 25th day of the cycle.

Side effects

When taking Dufaston, the development of adverse reactions is possible:

1. The hematopoietic system may respond to the drug with symptoms of hemolytic anemia.
2. From the side of the central nervous system, dizziness and headaches are possible.
3. From the genital area, sometimes there are breakthrough uterine bleeding, sometimes there is pain and swelling of the mammary glands.
4. On the part of the skin, allergic manifestations are possible in the form of urticaria, itching, skin rash. In very rare cases, there is a development of such complications as angioedema.
5. In some cases, there is a problem with the liver, expressed in weakness and malaise, jaundice, some patients note that after Duphaston, the stomach hurts.

Uterine bleeding when taking the drug is easily stopped by increasing the dose of Duphaston. If adverse reactions occur, you should consult your doctor, you may need to adjust the dose, and in case of allergic reactions, stop the drug.

Overdose

There have been no reports of overdose symptoms. In case of accidental intake at a dose significantly higher than the therapeutic dose, gastric lavage is recommended. There is no specific antidote, treatment should be symptomatic.

special instructions

Currently, there are no data on the negative effect of dydrogesterone in chronic renal failure.

A thorough clinical examination is required if a history of a progesterone-dependent tumor (eg, meningioma) is indicated, as well as in case of its progression during pregnancy or during previous hormonal therapy.

In the case of prescribing dydrogesterone in combination with estrogens (for example, for hormone replacement therapy), contraindications and warnings associated with the use of estrogens should be taken into account.

Before starting hormone replacement therapy (HRT), a complete history should be taken. During treatment, it is recommended to periodically monitor the individual tolerance of HRT. The patient should be informed about any changes in the mammary glands she should report to the doctor. Investigations involving mammography should be performed in accordance with conventional patient screening.

Sometimes during the first months of treatment, breakthrough uterine bleeding may occur. If breakthrough bleeding occurs after a period of taking the drug or continues after a course of treatment, the cause should be investigated, an endometrial biopsy should be taken to exclude malignant changes in the endometrium.

Do not prescribe Duphaston tablets to patients with genetically determined galactose intolerance, lactase deficiency or malabsorption syndrome.

drug interaction

There may be some decrease in the effectiveness of Duphaston when taken in parallel with Rifampicin or Phenobarbital, which affect microsomal liver enzymes. These drugs are able to increase the rate of biological transformation of the hormonal drug Duphaston.

To date, there have been no reports of drug incompatibility of Duphaston with other drugs.

With the parallel appointment of a progestogen with estrogens, it is advisable to take into account the indications and contraindications for the latter.

As it happens, when the menstrual cycle is stable, nothing needs to be taken to ovulate. But if you look around, you can see a lot of girls attending antenatal clinics, taking tests, undergoing treatment. Often, problems with conception are caused by hormonal disorders, and one of the drugs that solve these problems and is prescribed when planning a pregnancy is Duphaston. We'll talk about him.

When tests show that there is little in the body, doctors recommend the drug Duphaston. This remedy helps to restore normal and helps to get pregnant.

The medicine is prescribed when the body does not produce the right amount of progesterone. Sometimes it is not canceled until the third trimester - at this time it is already formed that produces progesterone. Even for a pregnant woman and a baby, the drug is absolutely safe. It also does not affect blood clotting, does not adversely affect the liver.

Is it possible to get pregnant after taking Duphaston? Yes, many gynecologists recommend this remedy, as it has shown itself to be excellent.

You can get pregnant on Duphaston - it compensates for the lack of progesterone and is its synthetic counterpart.

Doctors prescribe the drug in cases where problems with conception are associated with a lack of a hormone:

• uterine bleeding;
• amenorrhea.

It is important for the patient to know exactly how to drink Duphaston in order to get pregnant. The drug must be drunk on certain days of the menstrual cycle, otherwise it can act as a contraceptive.

Does Dufaston help to get pregnant? Yes, because it contains artificial progesterone, called the "pregnancy hormone." Under natural conditions, its production occurs in the postovular days of the cycle, preparing the uterus for a possible conception. To determine whether the cause of problems with conception is a deviation in the hormonal background, you need to contact the antenatal clinic and take tests.

How to drink the drug Duphaston when planning a pregnancy in the near future? It is usually taken from the 16th to the 25th day of the menstrual cycle. If pregnancy has occurred, then the reception continues until the 20th week, after which the dosage is gradually reduced.

Doctors prescribe the drug for at least three months. If conception has not occurred during this time, Duphaston can be taken up to 6 months.

The effect of the drug on the cycle

In a healthy woman, menstruation should be monthly. Infrequent cycle failures may be tolerable if they are intermittent. Long delays can be caused by an insufficient amount of progesterone. The indication for taking Duphaston is amenorrhea, which is caused by a malfunction of the ovaries. When “secondary amenorrhea” is diagnosed (no periods for more than 6 months), doctors prescribe hormonal treatment, which is combined with exercise and diet.

They drink Duphaston in the second phase of the cycle, making up for the deficiency of progesterone. Menstruation while taking the drug should become regular.

Sometimes women themselves begin to take the drug to combat amenorrhea without first consulting a doctor. This cannot be done, because even greater disturbances in the endocrine system may appear, which will be very difficult to cope with.

The drug can help prevent bleeding that occurs in the middle of the cycle, it also reduces pain during critical days. But to have a positive effect, you need to drink it regularly.

Contraindications for admission

Will Duphaston help me get pregnant? Of course, yes, but doctors must take into account both indications and contraindications for taking it. Wrong attitude to this issue can adversely affect a woman's health.

The main contraindications are as follows:

• chronic renal failure;
• hypersensitivity to the components of the drug;
• hereditary pathologies, for example, Dubin-Johnson and Rotor syndromes.

Before you drink Duphaston when planning a long-awaited pregnancy, you need to pay attention to your health. For example, if a patient has problems with the cardiovascular system or diabetes, then she needs to be careful when taking this drug. The doctor must constantly monitor the state of her health.

You can safely take Dufaston in order to get pregnant, as it is safe. The same applies to the period of pregnancy itself. But during lactation, it is desirable that the patient does not drink it. The main component of the drug, dydrogesterone, is excreted in mother's milk and makes it impossible to breastfeed the baby.

Correct drug intake

Before you drink Duphaston when planning a pregnancy, you need to read the instructions and remember that only a doctor can prescribe it. He monitors the patient, is familiar with the peculiarities of the course of the disease.

Admission rules for various pathologies:

• PMS and irregular critical days - from 11 to 25 days of the menstrual cycle. Dufaston when planning pregnancy in this case is taken at a dosage of 10 mg twice a day.
• Dysmenorrhea (mild critical days) - from 5 to 25 days. Dosage - twice a day, 10 mg.
• How to take Duphaston medicine to get pregnant with amenorrhea? From 11 to 25 days of the expected cycle. Dosage - twice a day, 10 mg. Additionally, you need to take estrogen.
• Duphaston for endometriosis during pregnancy planning is taken from 5 to 25 days. Dosage - 3 times a day, 10 mg.
• In case of infertility due to a lack of progesterone, the drug is taken from the 14th to the 25th day of the cycle. When planning pregnancy, the dosage of Duphaston in these circumstances is 10 mg once a day. The course lasts 6 cycles in a row. If Duphaston helped to get pregnant, then you should not stop taking it for another 3 months.
• The drug copes well with uterine bleeding. In this case, you need to take it for 7 days, twice a day, 10 mg.

Use during pregnancy

So, while taking Duphaston, you can get pregnant, but is it allowed to drink it after conception? Pregnancy sometimes proceeds with complications, so it is necessary to take this remedy in order to safely endure the baby. If uterine is observed, then the doctor may extend the course of therapy.

Refusal of the drug is developed by the doctor, since abrupt cancellation often provokes a negative reaction. If the pregnancy proceeds normally, the dosage of the drug is reduced by half, and the woman's well-being is controlled by the supervision of the attending physician. If there are fluctuations in the level of the hormone progesterone due to a decrease in dosage, the process of refusing the drug will continue for another 2-3 weeks.

Those who helped Dufaston get pregnant should remember that it should not be drunk after childbirth, because it has a negative effect on the baby's body, getting there along with mother's milk.

Duphaston or Utrozhestan - which is better?

The role of the first drug in planning conception and a successful pregnancy is well known. However, there are also effective analogues.

The main competitor of this drug - - when planning conception is also very effective. The drug contains progesterone, made from plant materials. For this reason, it is used in exactly the same way as its counterpart described above. There is no big difference in what to use when planning a pregnancy - Duphaston or Utrozhestan. Which particular drug to give preference to, the doctor decides.

The difference between these medicines is that Duphaston is a synthetic drug, and Utrozhestan is natural. But the former has far fewer side effects.

A significant difference between these drugs is that Utrozhestan can not only be drunk, but also injected directly into the vagina, which prevents the development of allergic reactions. And what kind of drug to prescribe for therapy, the doctor will decide.

Side effects of taking Duphaston

Duphaston can be used when planning a pregnancy because it has few side effects. It does not affect ovulation, and conception often occurs when taking it. But it is not 100% safe. There are such side effects as nausea, dizziness, bloating.

Taking Duphaston when planning pregnancy in rare cases can cause liver dysfunction and anemia. It is not recommended to take it to women with pathologies of the heart, liver, kidneys, pancreas.

To prevent side effects, you need to know how to properly take synthetic Duphaston when planning a pregnancy. To begin with, an examination is carried out, on its basis the gynecologist determines the duration of the intake and the desired dosage.

When the doctor recommends drinking Duphaston when planning a pregnancy, you do not need to refuse - the drug is safe if you follow the instructions for its use. The medicine has worked well. If a woman is interested in whether it is possible to get pregnant on Duphaston, then she needs to know that only the correct use of this drug under the supervision of a specialist will help solve the problem.

Useful video about pregnancy planning

Answers

In the proposed article, we will talk about a hormonal drug called Duphaston, which is currently widely used in the treatment of female diseases. We will discuss detailed instructions for the use of the remedy and consider cases in which you should not use this drug.

» instructions for use

• To date, Duphaston is the most commonly used hormonal drug in the field of gynecology. This drug is similar in its properties to the hormone progesterone.
• In accordance with the days of the female menstrual cycle, the predominance of the hormones estrogen and progesterone is cyclically replaced, and an insufficient amount of progesterone in the female body can cause the development of various pathologies
• Progesterone is involved in the process of preparing the female body to maintain and carry a pregnancy. Since an insufficient amount of this female sex hormone can cause the development of diseases, the drug Duphaston is often prescribed by gynecologists for therapy

« Duphaston "when planning pregnancy

"Dufaston" when planning pregnancy

• Since Duphaston is an analogue of progesterone, the pregnancy hormone, it is often prescribed during pregnancy planning and gestation.
  The substance has a high rate of absorption from the gastrointestinal tract and the maximum substance in the blood plasma occurs after 2 hours
• To ensure a sufficient level of progesterone in the blood of a woman during pregnancy planning, a special scheme for its administration has been developed.
• It is prescribed in the second phase of the menstrual cycle after the onset of ovulation, that is, on average from 11 to 25 days of this cycle. During this time, it is recommended to take 1 tablet of the drug 1 time per day. If necessary, the dose of the drug is increased by the attending gynecologist
• For a positive effect of treatment, the drug is prescribed for a duration of 6 months, and only after this period is it recommended to plan the conception of a baby. The same recommendations apply to preparing a woman for IVF.
• Before prescribing a course of this therapy, it is necessary to pass a series of tests for the content of sex hormones in the blood and determine their level at the moment before starting therapy with Duphaston
• For the accuracy of the tests taken, it is necessary to know exactly the day of ovulation, for this, a woman must monitor her basal temperature for a month
• It should be noted that pregnancy occurs already at 3-6 months of Duphaston therapy.

« Duphaston" on the days of the cycle "Dufaston" from the 16th to the 25th day of the cycle

"Dufaston" on the days of the cycle "Dufaston" from 16 to 25 day of the cycle

• Strange as it may sound, not all women correctly calculate their menstrual cycle. Therefore, to begin with, let's determine how long a woman's cycle lasts
• The days of the cycle begin to count from the first day of the onset of menstruation to the first day of the onset of the next menstruation. On average, this period is 28 days, but the interval from 25 days to 35 on average can serve as the norm.
• As we mentioned earlier, for treatment in preparation for conception, Duphaston is prescribed for admission after ovulation. This is done in order to get into the biological rhythm of increasing the concentration of progesterone in the female body. And this happens precisely in the second phase of the menstrual cycle.
• Depending on the day of ovulation and the length of the cycle, this period falls in the middle of the time interval between the beginning of the last two menstruation
• For example, if your cycle lasts 25 days, and ovulation occurred on the 16th day of the cycle, then Duphaston is prescribed from the 16th to the 25th day. Then the reception is interrupted until the next ovulation

Menstruation after Duphaston

Menstruation after "Duphaston"

• Duphaston is prescribed precisely in those cases when the menstrual cycle is disruptive and delayed due to a lack of the hormone progesterone in the female body. Normally, progesterone affects the endometrium of the uterus, stimulating its thickening and loosening. All these processes prepare the uterus for implantation. fertilized eggs
• With a shortage of the hormone, the endometrium does not grow and menstruation may be scarce or absent altogether. In this case, the drug is most effective
• Duphaston does not have a depressing effect on the reproductive function of the ovaries, therefore, in the absence of ovulation, it is also prescribed. At the same time, progesterone artificially provokes the onset of menstrual bleeding, and when it is canceled, ovarian function is often recovering on one's own

« Duphaston » indications for use

"Dufaston" indications for use

Duphaston is prescribed not only in planning or maintaining pregnancy. This drug has a number of indications for use in the following diseases:

development threat spontaneous abortion
Infertility due to lutein deficiency
Endometriosis
habitual abortion
Premenstrual syndrome (PMS)
Algodysmenorrhea(painful passage of menstruation and violation of the cycle)
Amenorrhea (lack of menstruation)
Uterine bleeding associated with dysfunction
Hormone Replacement Therapy
Maintaining or planning a pregnancy

« Duphaston » dosage

"Dufaston" dosage

For each of these diseases, a specific course of treatment with this drug is prescribed with a specific regimen. The dose of use can vary quite a lot, depending on the indications of the content of the hormone progesterone in the woman's blood.

The duration of the course, the regimen and the dose of taking this drug can only be determined by the attending gynecologist. Do not take the remedy on your own, as uncontrolled intake of the hormone can harm you.

Average doses:
With endometriosis 10 mg up to 3 times a day (5-25 days of the cycle)
Infertility -10 mg 1 time per day (14-25 days of the cycle)
Threatened miscarriage 10 mg 2 times a day (up to 20 weeks)
PMS - 10 mg 2 times a day (11-25 days of the cycle)

Remember!!! The scheme and dose of admission is prescribed only by the doctor.

« Duphaston side effects

"Dufaston" side effect

Side effects of taking this drug include the following conditions:

Development iron deficiency anemia
The development of allergic reactions to the constituent components of the drug
Migraines and headaches
Very rarely, so-called breakthrough uterine bleeding can develop, associated with a high level of progesterone in the blood, while the breasts can also swell and be painful on palpation
The liver can also very rarely be affected. accompanied the development of pain in the epigastric region and symptoms of hepatitis
Skin manifestations of an allergic reaction in the form of itching and redness, an edematous condition may also develop

« Duphaston » contraindications

"Dufaston" contraindications

The drug is contraindicated in the following conditions:
When an increased sensitivity to this drug or its constituent components
Marked itching or redness of the skin during previous pregnancies
Do not prescribe "Dufaston" in the presence of malabsorption syndrome or with intolerance galactose woman
With caution, the drug is prescribed if a woman has migraines, a history of epileptic seizures and metabolic diseases
When using a drug for substitution therapy, constant ultrasound monitoring of the condition of the pelvic organs and regular mammography are required.

« Duphaston » for children

This drug is not usually prescribed in childhood. The exception is the onset of puberty in a girl and the impossibility of establishing her menstrual cycle for up to a year.

If the cycle has not been established, then it is possible to use hormonal drugs, but strictly according to the prescription of a pediatric gynecologist and under the control of blood tests and other research methods.

« Duphaston » analogues

The drug has no structural analogues. He has others patented names :
Utrozhestan
Prajesan

Video: Duphaston

One of the most commonly prescribed drugs in gynecological practice is duphaston, a synthesized analogue of the natural female hormone progesterone, which is necessary for a number of important biological changes in the female body. All these adjustments serve one great purpose: preparing for pregnancy and ensuring its normal course. The results of the activity of progesterone are manifested in an increase in the secretory activity of the uterus, suppression of the contractile activity of its smooth muscle fibers, suppression of the immunological reactions of rejection of the embryo by the mother's body, and much more.

Modern pharmaceuticals has several effective substitutes for this hormone at once, but most of them were synthesized on the structural basis of male sex hormones, and therefore their intake is accompanied by such side effects as the appearance in women of secondary male sexual characteristics in the form of increased body hair on unusual for the female body areas (beard, mustache), coarsening of the voice, acne, etc. In addition, there may be complications in the functional activity of the liver and a shift in the ratio of lipid blood fractions.

Duphaston, on the other hand, has a completely different chemical structure, which has nothing to do with male sex hormones. On the contrary, it is as close as possible to the structure of progesterone produced by the body itself. Therefore, its use is not associated with the negative effects inherent in most similar drugs. Moreover, due to certain components, some experts tend to consider duphaston even more preferable than a natural natural hormone.

Duphaston is a very popular pharmacological drug that has been successfully used to treat pathologies caused by a lack of the female hormone progesterone. However, improper use of the drug can seriously harm your health. Therefore, it is so important to listen to the recommendations of doctors on how to use Duphaston.

Different pathologies - one solution

The importance of progesterone for women's health cannot be overestimated. The lack of this hormone leads to many pathologies: endometriosis, menstrual irregularities, difficulty conceiving , habitual miscarriages and other serious problems.

In the event that a woman's body does not produce enough progesterone, synthetic analogues come to the rescue.

The hormone dydrogesterone, which is part of Dufaston, is as close as possible in its composition to natural progesterone, therefore this drug is actively used in hormone replacement therapy and to combat diseases caused by progesterone deficiency in the body.

Purpose

Duphaston is used for infertility associated with functional insufficiency of the corpus luteum, "habitual" abortions associated with increased activity of uterine smooth muscles, various menstrual disorders, endometriosis, etc. In combination with other medications, duphaston is effective in the treatment of uterine bleeding and the pathological absence of menstruation . This drug is often prescribed after estrogen treatment in order to prevent cancerous transformation of the uterine mucosa that has grown against the background of estrogens.

Contraindications for treatment with duphaston are some liver diseases resulting in an increase in the amount of bilirubin in the blood. Also, you can not use the drug in the presence of allergic reactions to its constituent ingredients. With caution, the drug is used in the presence of severe diseases of the heart and kidneys, as well as in epilepsy. If there are appropriate indications, the medication is allowed to be taken during pregnancy, but it is undesirable during the feeding period due to the ability to be excreted in breast milk. Duphaston practically does not have side effects, however, uterine bleeding is sometimes possible.

Reviews about the action of duphaston are mostly positive: the drug does not have a depressing effect on the reflex reactions of the nervous system, so it does not impair the ability to drive a vehicle. Patients taking duphaston can lead a full life.

How to use duphaston

Duphaston is taken orally (that is, through the mouth), as it is very quickly absorbed from the gastrointestinal tract. After a couple of hours, the concentration of the drug in the blood reaches its maximum, however, it is very quickly excreted: after a day, only 15% of the drug remains in the body, and after three days it does not remain at all. Hence the two- or three-time intake regimen during the day. The main route of elimination is through the kidneys.

Dufaston can be safely combined with other drugs. Almost the only medications that are not recommended to be combined with duphaston due to the weakening of its therapeutic effect are phenobarbital homologues.

Despite a minimum of contraindications and side effects, duphaston should not be used as part of self-medication. So, before prescribing a therapeutic course with this drug, a general medical, including a gynecological examination, is necessary. It is also advisable to take a chest X-ray, the frequency of which will be determined by the attending physician.

Correct Application

Duphaston is taken orally, in the form of tablets. This method of administration is undoubtedly more convenient than injections, since a woman can be treated on her own. Within two hours, the concentration of the hormone in the blood is maximum. The drug is excreted through the kidneys, and this also happens quickly: already three days after taking Duphaston, there is not a trace of it left. That is why regular intake of this drug is recommended, which allows you to constantly maintain the required concentration of the hormone in the body.

Methods of application and doses of Duphaston depend on which pathology needs to be eliminated.

So, for the treatment of endometriosis, Duphaston should be drunk from the fifth to the twenty-fifth day of the cycle, ten milligrams daily two to three times a day. According to the same scheme, you should drink the drug for dysmenorrhea.

With irregular menstruation and premenstrual syndrome, Dufaston is prescribed twice a day, one tablet from the eleventh to the twenty-fifth day of the cycle. For the treatment of amenorrhea Duphaston is drunk according to the same scheme, in addition, estrogen preparations are also taken from the first to the twenty-fifth day of the cycle.

To stop dysfunctional uterine bleeding, Duphaston is taken for five to seven days, ten milligrams twice a day. To prevent bleeding, the drug should be drunk from the eleventh to the twenty-fifth day of the cycle twice a day for ten milligrams.

This drug is used to treat infertility caused by luteal insufficiency. The course of treatment is at least six months (six cycles in a row), and when pregnancy occurs, it is recommended to continue taking Duphaston for several months, as with a habitual abortion. The drug should be taken once a day, one tablet from the fourteenth to the twenty-fifth day of the cycle.

Together with estrogen, Duphaston is used in hormone replacement therapy. The dosage regimen depends on the estrogen regimen. So, if estrogens are taken continuously, then Duphaston is prescribed one tablet per day for fourteen days. This is followed by a two-week break, and the drug is again resumed for fourteen days. If estrogens are taken on a cyclic basis, Duphaston should be taken one tablet per day during the last twelve to fourteen days of estrogen intake. In this case, regular ultrasound examinations are prescribed to monitor the effect of the drug. In some cases, the dose of Duphaston is indicated to be increased to twenty milligrams per day.

During pregnancy

With a habitual abortion, Duphaston must be taken until the twentieth week of pregnancy, one tablet twice a day every day. After that, the doctor gradually reduces the dose of the hormone. It is very important that the dose reduction be exactly gradual: a sharp refusal to take the drug can provoke a miscarriage.

Duphaston is also indispensable in case of a threatened abortion: if dangerous symptoms appear, you should drink 4 tablets once, and then drink ten milligrams of Duphaston every eight hours until the symptoms disappear.

The drug Duphaston is a hormonal agent that has a fairly wide spectrum of action and helps to deal with the problems of the female genital area. This is polycystic ovaries, and disruptions in the menstrual cycle, and endometriosis, and even infertility. How does he act in each of these cases?

Features of the drug

Duphaston is an analogue of the female hormone progesterone dydrogesterone, created in a laboratory. It is absolutely safe for the body. In its structure, the drug is very similar to a natural hormone.

It has an effect on the uterine mucosa, in particular, on the receptors that are most sensitive to it.

Lack of progesterone in the body leads to headaches, mood swings, swollen breasts and swelling of the abdomen, excessive fatigue. If this is the period before menstruation, an insufficient amount of the hormone leads to a sharp weight gain and severe pain in the lower abdomen. Duphaston helps to solve these problems.

Why accept?

Why is Duphaston prescribed in each case? Its action depends on the situation.

Before conception

When planning a pregnancy, a woman needs to be tested for the level of progesterone in the blood. If it is underestimated, the doctor will prescribe Duphaston as the main treatment. It will speed up conception and contribute to an easy pregnancy in the first 3-4 months.

There are several cases when treatment with Duphaston is mandatory:

Problems with the endometrium

When a woman's body lacks progesterone, the endometrium (uterine lining) greatly increases in size. It can flake off the walls of the uterus and cause severe bleeding.

In most cases, Duphaston helps to defeat this disease:

When the pregnancy has already begun

Why is Duphaston prescribed to pregnant women:

1. During pregnancy, the drug reduces the tone of the uterus, which can provoke a miscarriage or premature birth.
2. Participates in the preparation of the breast for feeding.
3. Helps the body store the fat needed to carry a baby.
4. Stops the process of removing the fetal egg from the uterus (spontaneous abortion).
5. Improves the condition of the endometrium.

Disruptions in the hormonal system

In the work of the reproductive system of a woman, disturbances may occur. They are caused by different reasons. Most often, violations relate to the menstrual cycle. These are dysmenorrhea (severe pain in the lower abdomen before and during menstruation), severe premenstrual syndrome (PMS), amenorrhea (no menstruation).

How does Dufaston deal with these problems? Regular menstruation is a sign that a woman's body clearly performs all its functions. The duration of the menstrual cycle is on average 28 days. If there is no menstruation after this time, then a failure has occurred. It is usually caused by disorders in the hormonal system, in particular, a lack of progesterone. Dufaston is prescribed in order to bring the menstrual cycle back to normal.

What does the correct cycle look like? In the second week of the cycle, the ovary membrane ruptures, after which a mature egg emerges from it. At the same time, the corpus luteum appears, which is responsible for the production of progesterone. A sufficient amount of it triggers such important processes as the growth and renewal of the endometrium. It also allows the body to bear the child.

A low level of progesterone does not allow to finish the job, and Duphaston helps the mother's body cope with the task assigned to it.

At the moment when the level of progesterone returns to normal, the menstrual cycle becomes regular. Sometimes disorders in the hormonal system lead to the appearance of neoplasms. Cysts form in the cavity of the corpus luteum. They will resolve themselves if there is enough female hormone in the body. Otherwise, the cyst will continue to grow. Reception of Duphaston in this case is mandatory.

Polycystic

Polycystic ovaries is a disease associated again with disorders in the hormonal system. Duphaston is prescribed in order to normalize the hormonal background.

Women who suffer from polycystic ovaries are more at risk of miscarriage than others. In the early stages, they may have a miscarriage, or spontaneous abortion. Preterm labor or isthmic-cervical insufficiency (the cervix can no longer hold the fetus in the womb) often occurs.

With polycystic disease, Duphaston is prescribed until the 16th week of pregnancy. It is during this period that the placenta itself begins to produce progesterone.

Important Rules

Duphaston is a hormonal drug. Therefore, it should be prescribed exclusively by the attending physician. He also determines the dose and duration of treatment. The use of Duphaston must obey certain rules:

How to use

The dosage of the drug depends on the specific case.

Sometimes Duphaston is prescribed for menopause. It is usually combined with other drugs that restore the hormonal background of a woman. The duration of treatment is 14 days.

Duphaston is a synthetic hormone that has a huge effect on a woman's body. It not only restores the endometrium and promotes its renewal, but also prevents the formation of cysts and polyps in the uterus. Duphaston promotes the conception and fixation of the embryo in the uterus, after which the fetus can grow and develop. Thanks to him, the risk of premature birth is minimized.

This remedy regulates the menstrual cycle and restores a woman's ability to have children. But it is worth remembering that this is a hormonal medicine, and only a doctor should prescribe it.