Dibazol indications. Dibazol (solution): instructions for use

One tablet contains

active substance - bendazole 20.0 mg,

excipients: sugar, potato starch, anhydrous colloidal silicon dioxide (aerosil), calcium stearate.

Description

Tablets are white or white with a slightly grayish or yellowish tint, with a flat surface. On one side of the tablet there is a chamfer and a risk, on the other - a chamfer and a company logo in the form of a cross.

Pharmacotherapeutic group

Peripheral vasodilators. Other peripheral vasodilators

ATX Code S04AX

Pharmacological properties

Pharmacokinetics

Bendazole, when taken orally, is rapidly absorbed from the gastrointestinal tract. It is biotransformed by methylation and carboethoxylation of the imino group of the imidazole ring of bendazole, forming two conjugates: 1-methyl-2-benzylbenzimidazole and 1-carboethoxy-2-benzylbenzimidazole.

Metabolized in the liver.

The effect of the drug appears 30-60 minutes after administration, the duration of the hypotensive effect is 2-3 hours.

It is excreted mainly with urine.

Pharmacodynamics

Vasodilator and antispasmodic. It has a hypotensive, vasodilating effect, stimulates the function of the spinal cord, has a moderate immunostimulating activity.

It has a direct antispasmodic effect on the smooth muscles of blood vessels and internal organs. The drug causes a short (2-3 hours) and moderate hypotensive effect, well tolerated.

Causes a short expansion of the cerebral vessels in chronic hypoxia of the brain caused by local circulatory disorders (sclerosis of the cerebral arteries).

Facilitates synaptic transmission in the spinal cord.

It has immunomodulatory activity. By regulating the ratio of concentrations of cyclo-guanosine monophosphate (cGMP) and cyclo-adenosine monophosphate (cAMP) in immune cells, it increases the content of cGMP, which leads to the proliferation of mature sensitized T- and B-lymphocytes, the secretion of factors of mutual regulation by them, a cooperative reaction and activation of the final effector cell functions. The drug stimulates the production of antibodies, enhances the phagocytic activity of leukocytes, macrophages, improves the synthesis of interferon, but the immunomodulatory effect develops slowly.

Indications for use

Spasm of smooth muscles of internal organs in peptic ulcer

stomach and duodenum, pylorospasm

Residual effects of poliomyelitis, peripheral facial paralysis

nerve, polyneuritis

Dosage and administration

With spasms of smooth muscles of the internal organs Adults: the drug is administered orally 2 hours before or 2 hours after a meal, 1-2 tablets (20-40 mg) 2-3 times a day.

The duration of the course of treatment is determined by the doctor, on average it is 3-4 weeks.

With residual effects of poliomyelitis, peripheral facial paralysis

nerve, polyneuritis

Adults and children over 12 years of age: ¼ tablet (5 mg) once a day,

daily or every other day, for 10-15 days.

A second course of treatment is carried out after 3-4 weeks.

In the future, courses of treatment with the drug are carried out with a break of 1-2 months.

Side effects

Allergic reactions (skin itching, hyperemia, rash, urticaria)

Dizziness, headache

Feeling hot, sweating, redness of the face

Nausea

Tachycardia, low blood pressure

Contraindications

Hypersensitivity to bendazole or other excipients

drug components

Diseases that occur with a decrease in muscle tone, convulsive

syndrome

Arterial hypotension

severe heart failure

Peptic ulcer of the stomach and duodenum, complicated

bleeding

Children's age up to 12 years

Drug Interactions

With the combined use of the drug with papaverine hydrochloride, theobromine, salsolin, the spectrum of their pharmacological action expands.

With the combined use of Dibazol with barbiturates, the effectiveness of long-acting barbiturates, in particular phenobarbital, is enhanced.

Dibazol is not compatible with salicylates and benzoates, since precipitation occurs when used together.

When combined with beta-blockers, the hypotensive effect of the drug does not change, but with long-term administration, it prevents an increase in total peripheral vascular resistance caused by beta-blockers.

Combination with phentolamine enhances the hypotensive effect (phentolamine and dibazole lead to a decrease in total peripheral vascular resistance).

The drug enhances the hypotensive effect of clonidine, reserpine, saluretics, agents that affect the renin-angiotensive system.

special instructions

Application in pediatrics

The drug is not used in children under the age of 12 years.

Pregnancy and lactation

Since there are no data on the safety of the drug for the fetus, its use during pregnancy is not recommended.

During lactation, it should be used with caution only if the benefit to the mother outweighs the potential risk to the child.

Features of the effect of the drug on the ability to drive vehicles and potentially dangerous mechanisms

During treatment, care should be taken when driving vehicles and working with potentially dangerous mechanisms due to possible side effects such as dizziness.

Solution contains 2 ml, 5 ml

active substance - bendazol 20.0 mg, 50.0 mg

excipients: ethanol 96%, glycerin (in terms of 100%), hydrochloric acid 0.1 M, water for injection.

Description

Clear colorless or slightly colored liquid

Pharmacotherapeutic group

Peripheral vasodilators. Other peripheral vasodilators

ATX Code S04AX

Pharmacological properties

Pharmacokinetics

When administered intramuscularly, the drug quickly penetrates into the systemic circulation. The maximum concentration in the blood is observed after 15-30 minutes from the moment of administration. Duration of action - 2-3 hours. Metabolized in the liver.

The biotransformation products of dibazole are two conjugates formed as a result of methylation and carboethoxylation of the imino group of the imidazole ring of dibazole: 1-methyl-2-benzylbenzimidazole and 1-carboethoxy-2-benzylbenzimidazole.

Metabolic products are excreted mainly in the urine.

Pharmacodynamics

Vasodilator and antispasmodic. It has a hypotensive, vasodilating effect, stimulates the function of the spinal cord, has a moderate immunostimulating activity.

It has a direct antispasmodic effect on the smooth muscles of blood vessels and internal organs. The drug causes a short (2-3 hours) and moderate hypotensive effect, well tolerated.

Causes a short expansion of the cerebral vessels in chronic hypoxia of the brain caused by local circulatory disorders (sclerosis of the cerebral arteries).

Facilitates synaptic transmission in the spinal cord.

Indications for use

Hypertensive crises as an additional remedy

Spasm of smooth muscles of internal organs in peptic ulcer

stomach and duodenum, pylorospasm

Residual effects of poliomyelitis, peripheral facial paralysis

nerve, polyneuritis

Dosage and administration

The drug is used intravenously, intramuscularly or subcutaneously.

For the relief of hypertensive crises, 30-40 mg (3-4 ml of a 1% solution) are administered. With a significant increase in blood pressure, intramuscular administration of 20-30 mg (2-3 ml of a 1% solution) 2-3 times a day is indicated.

The course of treatment is prescribed individually, the average is 8-14 days.

With spasms of smooth muscles of internal organs, 10-20 mg (1-2 ml of a 1% solution) intramuscularly or subcutaneously as symptomatic therapy.

In the treatment of nervous diseases, the drug is prescribed for adults at a dose of 2 ml 1 time per day or every other day for 10-15 days intramuscularly or subcutaneously.

Repeated course in 3-4 weeks. In the future, courses of treatment with the drug are carried out with a break of 1-2 months.

Side effects

Allergic reactions (skin itching, hyperemia, rash, urticaria)

Local reaction (local pain at the injection site)

Dizziness, headache

Feeling hot, sweating, redness of the face

Nausea

Tachycardia, low blood pressure

Contraindications

Hypersensitivity to bendazole or to auxiliary

drug substances

Diseases that occur with a decrease in muscle tone,

convulsive syndrome

Arterial hypotension

severe heart failure

Peptic ulcer of the stomach and duodenum, complicated

bleeding

Children's age up to 12 years

Drug Interactions

With the combined use of the drug with papaverine hydrochloride, theobromine, salsolin, the spectrum of their pharmacological action expands.

With the combined use of Dibazol with barbiturates, the effectiveness of long-acting barbiturates, in particular phenobarbital, is enhanced.

Dibazol is not compatible with salicylates and benzoates, since precipitation of these drugs occurs.

Combination with phentolamine enhances the hypotensive effect (phentolamine and dibazole lead to a decrease in total peripheral vascular resistance).

The drug enhances the hypotensive effect of clonidine, reserpine, saluretics, agents that affect the renin-angiotensive system.

special instructions

Application in pediatrics

The drug is not prescribed to children under the age of 12 years.

Pregnancy and lactation

Since there are no data on the safety of the drug for the fetus, its use during pregnancy is not recommended.

During lactation, it should be used with caution only if the benefit to the mother outweighs the potential risk to the child.

Features of the effect of the drug on the ability to drive vehicles and potentially dangerous mechanisms

During treatment, care should be taken when driving vehicles and working with potentially dangerous mechanisms due to possible side effects such as dizziness.

Overdose

Symptoms: sweating, feeling hot, dizziness, nausea, mild headache, arterial hypotension, which quickly pass when the dose is reduced or the drug is discontinued.

Treatment: drug withdrawal. With severe arterial hypotension under the control of blood pressure, transfusion therapy, vasopressor agents, and cardiac glycosides are prescribed.

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Latin name: Dibazol/ Dibazolum.

INN(international non-proprietary name): Bendazol / Bendazolum.

Group of drugs: Dibazol refers to myotropic antispasmodics.

Release form

1. Tablets 2; 3; 4 mg for children and 20 mg N10 for adults.
2. Ampoules of 0.5% and 1% solution, 1 each; 2 and 5 ml for parenteral administration.

Composition of Dibazol

Active ingredient: bendazole (2-benzylbenzimidazole hydrochloride)
Auxiliary components: talc, lactose, potato starch, calcium stearate, polyvinylpyrrolidone.

Physicochemical characteristics

White crystalline powder with a grayish or yellowish tint, bitter-salty taste. It is difficult to dissolve in water, quite easily soluble in alcohol. Hygroscopic.

pharmachologic effect

It has myotropic (effect on muscles), antispasmodic, vasodilating and moderate, short-term hypotensive (lowering pressure) action. It affects the smooth muscles of blood vessels (arterioles and venules) and vessels of internal organs. By reducing the tone of blood vessels, Dibazol thereby reduces blood pressure and increases blood supply to areas of myocardial ischemia, which is observed in coronary heart disease. Able to stimulate interneuronal transmission in the synapses of the spinal cord, which is widely used in neurology.

Dibazol also has a moderate immunomodulatory activity, as it is similar to levamisole, which is a drug that stimulates immune processes. The immunostimulating effect of Dibazol is due to the ability to enhance the production of endogenous interferon.

Indications for use

Early stage of arterial hypertension.
Diseases of the internal organs, accompanied by spasms of smooth muscles (gastric and duodenal ulcers, spasms of the pylorus and intestines, hepatic and renal colic, etc.).
Neurological diseases, especially residual symptoms of polio in children, the consequences of birth injuries, facial paralysis and other diseases of the nervous system in the recovery stage.
As a mild immunostimulant (in combination with ascorbic acid and Thymogen, Dibazol is effective in combating influenza and other catarrhal viral infections).

Contraindications

1. Individual intolerance to the drug.

If the first symptoms of an overdose occur, it is necessary to stop taking Dibazol, and consult a doctor about the advisability of continuing to take the drug.

special instructions

The use of Dibazol in the elderly

It is considered inappropriate to prescribe Dibazol as an antihypertensive agent for a long time to the elderly, since the drug can have a negative effect on electrocardiogram parameters.

The use of Dibazol in pregnant women and during breastfeeding

Dibazol has found quite wide application as a means to lower blood pressure in obstetric practice. The drug is considered relatively safe, since no threatening effect of the main components of the drug on the fetus and on the child who is breastfeeding has been noticed.

An indication for the appointment of Dibazol during pregnancy is an increase in blood pressure above normal levels. This can occur with primary essential hypertension in a pregnant woman, with symptomatic hypertension (an increase in blood pressure is a symptom of another disease, such as glomerulonephritis, hyperthyroidism, etc.), with pregnancy complications (in particular, with gestosis).

With the injection route of administration, after 15-20 minutes, Dibazol begins to have a mild hypotensive effect, which is especially important in the state of pregnancy, since a sharp decrease in pressure in the mother can contribute to the appearance of fetoplacental circulation disorders, which is fraught with the development of intrauterine fetal hypoxia (i.e., its oxygen deprivation).

It must be remembered that during pregnancy, Dibazol is an emergency drug, and is not suitable for daily use.

With a persistent increase in blood pressure, it is necessary to select other antihypertensive drugs that are safe for the fetus and suitable for long-term use.

The use of Dibazol with other drugs

When Dibazol is taken together with drugs such as Reserpine, Clonidine, Phentolamine, an increase in the antihypertensive effect is observed, which must be taken into account when combined administration of several at once.

antihypertensive drugs of different groups.

The combination of Dibazol with papaverine hydrochloride significantly enhances the antispasmodic effect of both drugs.

Ascorbic acid enhances the immunostimulating effect of Dibazol.

The combination of Dibazol with papaverine

Quite often, Dibazol is combined with papaverine, which belongs to myotropic antispasmodics (quickly and effectively eliminates spasms of smooth muscles). When taken together, papaverine potentiates (enhances) the hypotensive and antispasmodic effect of Dibazol.

To achieve a quick effect, the drugs are prescribed in the following dosage: 0.5% 6-8 ml of Dibazol and 2% 4-6 ml of papaverine in one syringe, intravenously or intramuscularly.

It should be noted that the combination of Dibazol with papaverine is very favorable both during pregnancy and childbirth, but is completely unsuitable in the postpartum period. This is due to the direct effect of papaverine on the muscles of the uterus, followed by its relaxation, which is absolutely unacceptable immediately after childbirth, as it can lead to uterine hypotension and uterine bleeding. For these reasons, Dibazol is used in its pure form in the postpartum period.

Combined preparations with Dibazol

Dibazol is contained in some combined tablet preparations: Papazol, Andipal, Teodibaverin.

Tablets "Papazol" (Papazolum) contain 30 mg of papaverine and dibazol.
Indications for use: spasms of peripheral vessels, brain, mild arterial hypertension. It is prescribed 3 times a day, 1 tablet.

Tablets "Andipal" (Andipalum) contain 0.25 g of analgin, 0.02 g of phenobarbital and 0.02 g of dibazol. It is mainly used for vascular spasms. It has a vasodilating, antispasmodic and analgesic effect. It is prescribed 2-3 times a day for 1-2 tablets.

Tablets "Teodibaverin" (Theodibaverinum) consist of dibazole 20 mg, papaverine 20 mg and theobromine 15 mg.
Indications for use: vascular spasms of the brain, swelling of the legs and hands with heart and kidney failure.

It is prescribed up to 3 times a day, 1 tablet.

Analogues

There are several drugs with a similar structural structure for the active substance.

Bendazole;
Dibazol Darnitsa;
Dibazol UBF;
Dibazol Vial.

Storage conditions and shelf life

Dibazol belongs to the drugs of list B.

Dibazol powder is stored for 5 years, tablets and ampoules - up to 3 years.

Terms of sale in pharmacies

You can buy Dibazol in pharmacies without a doctor's prescription.

Dibazol: price

Buying the drug will not be difficult in any country, at a very affordable price.
Price in the Republic of Belarus: 0.5% solution 2 ml N10 - 7000 Bel. rubles; tablets 20 mg N10 - 3000 Bel. rubles.

In Moscow and St. Petersburg, the cost of the drug may vary in different pharmacies. Solution for injection 34-45 rubles, tablets 25-50 rubles.

In Ukraine, Dibazol can be bought for 1.5 gr. tablets 20 mg N10, and for 7-8 gr. ampoules of 1% solution of 2 ml of N10.

For more than 60 years, Dibazol has been produced at pharmaceutical factories, the use of which can still be called relevant. The drug is used in various fields of medicine, up to obstetrics. Therefore, today we will consider the instructions for using Diabazol, its price, reviews about it and the correct dosage.

Features of the drug

Dibazol is a drug that has a hypotensive, antispasmodic and vasodilating effect. According to the ATX code, it is referred to.

Compound

The main active ingredient is bendazole. Also, the drug contains auxiliary components such as talc, lactose, potato starch, calcium stearate and polyvinylpyrrolidone.

Dosage forms

The drug is supplied in the form of tablets with a dosage of 2, 3 and 4 mg (for children) and 20 mg (for adults),
as well as ampoules of 0.5% and 1% solution for parenteral administration.

The average cost of a solution is 50 rubles, the average price of tablets is 20 rubles.

pharmachologic effect

Dibazol is a vasodilator drug that:

reduces pressure;
dilates blood vessels;
stimulates the spinal cord;
has an antispasmodic effect on the smooth muscles of blood vessels and organs;
accelerates synoptic transmission in the spinal cord;

The drug has a moderate immunostimulating effect, which is due to the regulation of the concentration of cGMP and cAMP located in immune cells and the proliferation of sensitized lymphocytes. Taking Dibazol leads to a short expansion of the cerebral vessels, which determines its appointment for people suffering.

Pharmacodynamics and pharmacokinetics

When taken orally, the drug is rapidly absorbed from the gastrointestinal tract. The decrease in pressure occurs after 30-60 minutes. after taking the drug, lasts for 2-3 hours. With the introduction of an injection of Dibazol, the hypotensive effect develops after 15-20 minutes.

The pharmacokinetics of the drug is not described in detail.

Indications for Dibazol's use

Dibazol is prescribed for spasm of the coronary vessels, for example, coronary spasm or spasm of peripheral arteries, as well as during:

exacerbations;
spasm of smooth muscles of organs such as stomach ulcers, pyloric spasm, renal colic.
residual effects of poliomyelitis;
peripheral paralysis of the facial nerve;
polyneuritis.

Dibazol is often used to lower blood pressure in obstetric practice. Studies of the drug have shown that it does not have a strong effect on the developing fetus and the child who is breastfed.

However, Dibazol can be prescribed to a pregnant woman only in cases of emergency. If a woman has a persistent increase in pressure, then other antihypertensive drugs should be selected for daily intake.

Instructions for the drug

The instruction differs depending on the form of the drug. The solution for injection can be administered intravenously, intramuscularly and subcutaneously. Dosages are selected by the doctor depending on the patient's condition:

Patients over 18:
- with hypertensive crisis 3-5 ml;
- with exacerbation of hypertension 2-3 ml 2-3 r. per day intramuscularly. within 8-14 days;
Diabazol for children: 2.5-10 mg.

Persons over 12 years old are prescribed 20-50 mg of Dibazol 2-3 r. per day.
In diseases of the nervous system, 5 mg of the drug is prescribed every knocking - two.

Contraindications

The main contraindication to taking Dibazol is hypersensitivity to its components and. Also, contraindications to the prescription of the drug can be called:

violations of the kidneys;
peptic ulcer, accompanied by bleeding of the gastrointestinal tract.
diabetes;
convulsive syndrome;
diseases accompanied by reduced muscle tone;

With caution, the drug is prescribed to elderly patients, people whose work is related to the management of mechanisms and driving equipment, because Dibazol in some cases causes dizziness.

Side effects

Most often, Dibazol is well tolerated by patients, however, in rare cases it can cause:

dizziness;
arterial hypotension;
allergic reactions;

During the administration of the drug in the form of a solution, severe pain may occur in the injection area.

Content

With spasms of blood vessels, doctors prescribe the medical drug Dibazol (Dibazol). This medication expands the lumen of arteries and arterioles, normalizes blood pressure, strengthens the structure of the myocardium, supplies the affected areas with blood (with cardiac ischemia). Before starting the course, you need to individually consult with your doctor. Self-medication is contraindicated.

Composition and form of release

The drug Dibazol is produced in the form of tablets for oral administration and a solution for intravenous, intramuscular or subcutaneous administration. On 1 blister pack, 10 tablets are distributed. 1 carton pack contains 1, 2, 5 or 8 packs, instructions for use. A colorless solution is poured into 1, 2 or 5 ml ampoules with a concentration of 5 or 10 mg / ml. Features of the chemical composition:

pharmachologic effect

Dibazol is a myotropic antispasmodic, a benzimidazole derivative. The drug has antihypertensive, immunostimulating, tonic, antispasmodic, vasodilating, tonic properties. The active substance relieves muscle spasm of blood vessels and internal organs, acts on venules and arterioles, accelerates synaptic transmission in the spinal cord. Due to a decrease in cardiac output and expansion of peripheral vessels, blood pressure decreases, blood flow to the zones of hypoxia and ischemia increases.

Bendazole, having moderate immunomodulatory properties, enhances the production of the endogenous form of interferon. The drug is characterized by a high degree of absorption from the digestive tract. The desired therapeutic effect occurs 1 hour after the application of a single dose, lasts for 3 hours. The metabolic process occurs in the liver with the release of two metabolites, which are excreted by the kidneys in the urine, slightly through the intestines.

Indications for Dibazol's use

This medication is used in cardiology, neurology, gastroenterology. For example, this antihypertensive drug is prescribed for spasms of vascular smooth muscle tissue, as an independent treatment or as an adjuvant. The instructions for use also describe other medical indications:

flaccid paralysis syndrome;
hypertensive crisis;
paralysis of the facial nerve;
polyneuritis;
renal, hepatic colic;
early stage of arterial hypertension;
coronary spasm;
polyneuropathy;
stomach ulcer;
spasms of blood vessels, pylorus, intestines;
treatment of residual effects of poliomyelitis.

Method of application and dosage

Instructions for use Dibazol describes the form of release and recommended daily doses. The medicine helps not only with an increase in blood pressure in adults, it can also be used in pediatrics. To stop the acute stage of the disease, intramuscular or intravenous injections are prescribed, after the patient is transferred to the tablet form of bendazole.

Tablets Dibazol

This form of drug release is recommended at the initial stage of arterial hypertension and not only to relieve spasm of smooth muscles. The tablet is required to drink after a meal or 2 hours before a meal, do not chew in the mouth, drink plenty of water. Daily doses depend on the nature of the pathological process, as maintenance therapy they are 20-50 mg 2-3 times a day for 3-4 weeks.

Solution

To quickly lower blood pressure, the doctor prescribes an injectable Dibazol solution. The injections are painful, but provide a quick therapeutic effect. The course of treatment lasts 7-14 days. Daily doses and the way the drug enters the body depend on the diagnosis:

hypertensive crisis: intravenously, 3-5 ml;
exacerbation of hypertension: intramuscularly, 3 ml of solution three times in 24 hours;
neurology: 5 mg every other day for a course of 5-10 days.

Dibazol for children

According to the detailed instructions for use, the indicated medication, according to indications, can be used in pediatrics. Daily doses depend on the age of the small patient, the nature of the pathological process, and are adjusted by the attending physician on an individual basis:

special instructions

Dibazol in tablets and injections is carefully prescribed to elderly patients. Daily doses are adjusted individually. It is important to regularly monitor the level of blood pressure, indicators of cardiac activity (perform an electrocardiogram), kidney and liver function. The instructions for use also describe other recommendations for patients that you need to read before starting the course:

Long-term use of Dibazol for arterial hypertension is not recommended, doctors do not exclude the so-called "addictive effect".
During treatment, it is important to refuse to drive a vehicle, not to engage in intellectual activities and types of work that require a high concentration of attention.
Dibazol flu tablets must be taken for a long time - at least 1 month without a break.
Doctors recommend Dibazol to increase immunity. Under the influence of small doses, the production of interferons is stimulated, the level of interleukins, endorphins, natural killers and phagocytes increases.

Dibazol during pregnancy

The drug is not recommended for use during gestation, since clinical studies in this category of patients have not been conducted. The effect of bendazole on intrauterine development of the fetus has not been established. During lactation, it is also desirable to refrain from such a pharmaceutical appointment. Otherwise, the baby needs to be temporarily transferred to adapted mixtures.

drug interaction

Dibazol from pressure is prescribed as part of complex therapy. Instructions for use contains information about drug interactions:

In combination with beta-blockers, bendazole reduces peripheral vascular resistance.
Simultaneous use with diuretics and antihypertensive agents enhances the hypotonic effect.
Phentolamine in combination with bendazole enhances the antihypertensive effect of the latter.
The combination of Dibazol with papaverine hydrochloride enhances the antispasmodic effect of both drugs.
Ascorbic acid enhances the immunostimulating effect of bendazole.

Side effects

In most clinical cases, Dibazol treatment proceeds without complications. The instructions for use describe the following side effects:

from the digestive tract: nausea, rarely - vomiting;
from the nervous system: dizziness, migraine, convulsive syndrome;
on the part of the skin: urticaria, skin rash and itching;
others: increased sweating, pain in the injection area.

Overdose

With a systematic excess of the daily dosages of Dibazol, the patient experiences a feeling of heat, sweating increases, dizziness and nausea are disturbing. It is not excluded the appearance of allergic reactions on the skin. There is no specific antidote. With symptoms of an overdose, the patient needs to wash the stomach, take saline solutions with a laxative effect, for example, dilute the Polysorb adsorbent powder according to the instructions. Further treatment is symptomatic, on the recommendation of a doctor.

Contraindications

With increased sensitivity of the body to the synthetic components of the specified medication, such a pharmaceutical prescription must be abandoned. The instructions for use provide a complete list of medical contraindications:

arterial hypotension;
tendency to low blood pressure;
severe renal failure;
intestinal and gastric bleeding with peptic ulcer;
diabetes;
convulsive syndrome;
heart failure;
reduced muscle tone.

Terms of sale and storage

Dibazol is sold in pharmacies, is a prescription drug. After purchase, store the medicine in a cool, dark place, avoid exposure to sunlight. The shelf life of the solution in ampoules is 4 years, tablets - 5 years from the date of manufacture indicated on the package. Expired medicine must not be used.

Dibazol's analogs

If the effect of the drug has weakened or side effects have occurred at the initial stage of conservative treatment, it is recommended to choose an analogue. Reliable antihypertensive agents:

Bendazol. The drug provides a short hypotensive effect, has a minimum of contraindications. According to the instructions, the recommended dose varies from 0.02 to 0.05 g 2-3 times a day. The course of treatment lasts from 3 to 4 weeks.
Glyophene. The drug quickly relieves spasm of peripheral vessels, is intended for oral, intravenous or intramuscular use. Daily doses depend on the diagnosis and condition of the patient, are described in detail in the instructions.

Dibazol price

The cost of the drug in the form of a solution is less than 100 rubles. Tablets are cheaper - up to 60 rubles per pack. The medicine is affordable, available in all city pharmacies. The final price depends on the form of release, configuration, reputation of the pharmacy.