Is it possible to drink tablets with sweet soda. Dangerous mixture: what medicines should not be taken with tea, coffee and juices

According to doctors and pharmacists, no more than 20% of all patients strictly follow the doctor's prescriptions for taking medications. Most of those who are treated with various pills or potions, drops and syrups do not think at all about what they need to drink. In the course are cafes and tea, soda, mineral water with gas and even alcohol. As a result, some patients end up in the hospital with drug-induced alcohol poisoning, or suffer from their sores for years, because the wrong pills simply do not work. At the same time, they all stubbornly scold doctors!

Features of taking medications

Those chemical compounds that are the basis of the drug, when taking the drug, may react with the components of food or drink. This can not only reduce their effectiveness, but also lead to the formation of some toxic compounds. Toxins can harm the health of a patient who takes pills in the hope of healing. There may be such negative reactions as a decrease in the effectiveness of the drug, allergic reactions and digestive disorders, as well as poisoning. Therefore, before taking medicines, you need to think about how and with what they need to be washed down. Sweet soda, mineral sparkling water, coffee or tea, milk drinks for these cases, for the most part, are not suitable.

The joint use of tablets with tea, even herbal tea, often leads to a change in the chemical properties of medicines. The active substances contained in the composition of tea are to blame for this - tannin, caffeine and some other components. Thus, a combination with tannin can give, when used together with drugs, insoluble or toxic substances, which negatively affects the healing process. In addition, if you drink tea with medicines, they noticeably change the rate of absorption and assimilation. Such combinations are especially dangerous when using iron preparations, which give the precipitation of its toxic salts in the intestine.

Oral contraceptives can be considered typical examples of unsuccessful combinations of tea with pills, the effectiveness of which is significantly reduced. Antidepressants taken with tea are no less dangerous - their combined action gives overexcitation and insomnia, increased nervous tension.

Tea is not combined with antibiotics, neurological drugs, enzymes, nitrogenous substances, cardiovascular and many other drugs.

Coffee and antibiotics, and other unfortunate combinations…

It is highly recommended not to take any medicines with coffee drinks. The content of caffeine and many other active substances in them leads to a violation of the absorption and activity of antibiotics, anti-inflammatory drugs and sedatives. Often, antibiotics that were washed down with coffee lose their activity completely or, instead of a positive effect, have a toxic, negative effect, provoke an allergy. Caffeine almost completely neutralizes the effect of sedative and sedative pills, and also significantly reduces the analgesic effect of paracetamol, nurofen, and enhances the irritating effect of aspirin on the stomach.

Ethyl alcohol in combination with drugs increases their toxic effect on the liver, and many drugs provoke alcohol poisoning with severe symptoms, both during libations and in the morning. Some drugs give such a pronounced alcohol poisoning, even with a small intake of alcohol, that patients end up in a hospital. At the same time, it practically does not depend on the strength and type of drink, whether it be beer or wine, strong alcohol or cocktails. To avoid long-term alcohol poisoning, avoid drinking alcohol during treatment, and if you have a hangover, stop using dangerous medications (aspirin, antihistamines and antibiotics).

Why you can’t take medicine with dairy products: enzyme problems

Antibiotics, especially those of the tetracycline group, as well as enzymes taken to improve digestion, are not combined with milk. In addition, milk drinks slow absorption and inhibit the activity of many other drugs. It is not just that milk is recommended by traditional medicine for poisoning: its components are capable of binding many chemicals, including drugs. In addition to lowering the activity of enzymes, milk also interferes with the action of antacids (binding acid in the stomach), potassium and iron preparations.

It is forbidden to drink milk drinks with tablets and enzymes that have acid-resistant capsules, milk is capable of dissolving these shells, which prevents the drug from reaching the intestines.

Do not drink medicines with compotes, fruit drinks and juices. These drinks contain a lot of active fruit acids and biologically active components, which lead to the active destruction of chemical compounds in the basis of the drug or changes in their pharmacological properties. At best, the tablets will lose their activity, at worst, they will acquire allergenic or toxic properties. Antacids, sulfa compounds, and cardiac glycosides are at the highest risk of adverse effects when combined with these drinks. Juices can affect the composition of drugs for the treatment of the cardiovascular system and those that regulate blood cholesterol levels. Also, they disrupt the absorption of antibiotics and non-steroidal anti-inflammatory drugs. But they increase the effect of aspirin on the walls of the digestive tract to toxic effects.

Combinations of juices and compotes with drugs that affect the rheological properties of blood will also be difficult. So, taking cranberry fruit drinks and juices with avocados affects the absorption of warfarin, a drug used in the treatment of thrombosis.

We categorically do not combine grapefruit juice with any medicines, it contains many active substances that disrupt the absorption of drugs from the intestines and increase their toxic effects on the body.

What medications do not combine with is somehow not customary to discuss. The doctor believes that the patient knows everything himself or he will be prompted in a pharmacy. The pharmacist thinks that the doctor has told everything, again, the instructions for the drug are attached. And the unsuspecting patient comes home and, having opened the package, throws the insert away. For uselessness. As a result, drugs are taken at the wrong time and washed down with anything.

According to medical statistics, only 20% of patients more or less comply with the prescriptions of doctors. 60% forget completely - what, when and how to take. Another 20% consider medical recommendations to be something optional and unprincipled. The result, of course, is unpredictable: drugs do not help as expected, or become deadly.

The most common mistakes

Chemicals in medicines can react with drinks and food. Thus, they can not only reduce the effectiveness of treatment, but also damage health.

Remember: never drink medicines with what comes to your hand - soda, juice, tea, coffee, milk!

Coffee, tea and herbal teas change the properties of drugs

Tea in combination with some antidepressants leads to overexcitation, resulting in insomnia, nervous tension.

It is impossible to drink tablets with tea, especially if it is:

alkaloids (PAPAVERIN, PLATIFILLIN, CODEINE);
drugs used in neurology, psychiatry (AMINAZIN and some antipsychotics);
cardiovascular agents;
agents that stimulate the process of digestion,
agents for the treatment of stomach ulcers;
antibiotics;
nitrogen-containing agents (ANTIPIRIN, CAFFEINE, AMIDOPIRINE, CODEINE, PAPAVERINE, EUFILLIN).

Coffee very quickly removes antibiotics from the body: so quickly that they do not have time to be absorbed and produce the desired effect. In general, the effect of coffee can be unpredictable. In some cases, it inhibits the action of drugs, while in others, on the contrary, it enhances the medicinal effect (especially in the case of taking painkillers). The combination of painkillers (such as CITRAMON, CITRAPAR, PARACETAMOL, ASPIRIN) and large portions of coffee can have a very deplorable effect on the condition of the liver and other organs.

Combinations of coffee with drugs such as:

sedatives;
anti-inflammatory and analgesic (PARACETAMOL, ASPIRIN, etc.);
popular antibiotics of the penicillin series and erythromycin.

Anti-arrhythmia drugs and all drugs that regulate the functioning of the heart and blood vessels are best kept away from a cup of espresso, because caffeine increases blood pressure and speeds up the heartbeat. There is evidence that even a decaffeinated drink does not affect the functioning of liver enzymes in the best way, but this issue needs more research. Just in case, always find out if your doctor's prescription medication can be combined with coffee.

Very often, to enhance the effect, patients prefer to drink medications. herbal decoctions or tinctures, naively believing that by doing so they enhance the activity of certain drugs. In fact, everything happens with “exactly the opposite”. It is necessary to understand and remember: it is impossible to drink medicines with herbal decoctions! For example, a useful infusion of St. John's wort significantly reduces the properties of contraceptives and antidepressants.

Juices

Undoubtedly. Although with the caveat “not always and not to everyone” (read about this in). Knowing this, some people, in the hope of enhancing the positive effect, prefer to drink fresh juice with medicines. Plus and plus, in their opinion, should give 2 pluses.

In fact, this approach does not take into account the possible interaction of drugs with a huge amount of biologically active substances contained in any natural product. Juices and compotes contain fruit acids, that is, substances that destroy the structure of drugs, change their pharmacological effect. At risk:

antacids (to reduce the acidity of gastric juice);
cardiac glycosides (DIGOXIN, etc.);
sulfonamides (STREPTOCID, SULFALEN, etc.);
drugs to lower blood pressure and blood cholesterol levels.

When combined with other medications, juices can interact in unpredictable ways. They slow down the action of antibiotics ERYTHROMYCIN or AMPICILLIN (here ampicibarbiturates, nitrofurans), slow down the absorption of AMIDOPIRINE, IBUPROFEN, FUROSEMIDE. And the effect of ASPIRIN (acetylsalicylic acid), on the contrary, can increase to poisoning.

For those who take drugs that reduce blood clotting, it is advisable to learn by heart: no juice, especially cranberry! In this case, juices can become provocateurs of gastric bleeding.

Other fruits that can disrupt the enzyme are orange and pomelo, as well as noni and pomegranates.

Grapefruit juice

The most famous example is grapefruit juice, which can dramatically slow down the metabolism of a number of drugs in the patient's body, which can lead to unpredictable consequences, including death. Here is a brief history of this find.

year 2000. There were first reports that grapefruit juice does not mix well with various drugs. American scientists from the Mayo Clinic (Mayo Clinic) noticed: if you drink heart drugs with this drink, their concentration in the blood becomes dangerously high.

2004 The alarming observation was confirmed. An article published in The American Journal of Nursing described a fatal outcome that occurred after drinking grapefruit juice with lipid-lowering drugs.

The story is like a fairy tale with a sad ending. A patient with hypercholesterolemia was prescribed atorvastatin. After 2 months, the patient moved from the North of America to sunny Florida, the land of fruit and sun. It would seem good for his health! However, after a while, the man develops muscle pain, weakness, fever, he ends up in intensive care and dies of acute renal failure. During the "debriefing" it was found that the only change in the patient's life after moving to the south was that he began to drink 2-3 glasses of freshly squeezed grapefruit juice daily.

The researchers then suggested that the ingredients of the drink compete with some drugs for one of the hepatic microsomal enzymes - cytochrome P450 3A4, which metabolizes both the substances contained in the juice and drugs. The result of this is a significant change in the pharmacokinetics of the drug, which immediately affects the duration of its exposure and the effect it has.

2006 The hazardous substance has been identified. It turned out to be furanocoumarin, which gives grapefruit and juice from it a characteristic bitterness. The situation has turned out to be so serious that the US Food and Drug Administration (FDA) now requires all new drugs to be tested specifically for compatibility with grapefruit juice.

So, you will have to forget about grapefruit juice (especially freshly squeezed) if you are taking one of the following drugs (it should be noted that many of them are very popular in Russia):

anxiolytics: Alprazolam, Buspirone, Midazolam, Triazolam;
antiarrhythmic: amiodarone, quinidine;
antibiotics: Clarithromycin, Erythromycin, Troleandomycin;
antihistamines: fexofenadine;
anticoagulants: warfarin;
antiepileptic: Carbamazepine;
beta blockers: carvedilol;
calcium channel blockers: Diltiazem, Felodipine, Nicardipine, Nifedipine, Nimodipine, Nisoldipine, Verapamil;
hormonal preparations containing: Cortisol, Estradiol, Methylprednisolone, Progesterone, Testosterone;
immunosuppressants: Cyclosporine, Sirolimus, Tacrolimus;
HMG-CoA reductase inhibitors (lipipidemic): Atorvastatin, Fluvastatin, Lovastatin, Simvastatin;
serotonin reuptake inhibitors (antidepressants): sertraline, fluvoxamine;
xanthines: Theophylline;
treatment of benign prostatic hyperplasia: Finasteride;
opioid analgesics: Alfentanil, Fentanyl, Sufentanil;
antiviral: Amprenavir, Indinavir, Nelfinavir, Ritonavir, Saquinavir;
anthelmintic: Albendazole;
antifungal: Itraconazole;
antitussives: Dextromethorphan;
antitumor: Cyclophosphamide, Etoposide, Ifosamide, Tamoxifen, Vinblastine, Vincristine;
repotents: Sildenafil, Tadalafil.

It should be emphasized that the listed active substances, and trade names of drugs can be very diverse. The name of the active substance is written on the package and indicated in the instructions for the drug.

Milk

Milk tends to reduce the effectiveness of many medications. Not without reason, with its help, they used to save from poisons, and today people who have been poisoned are soldered.

Antibiotics of the tetracycline series (TETRACYCLINE, OLETETRIN, etc.) are absolutely incompatible with milk and dairy products. Calcium cations from dairy products can bind drugs into strong compounds that do not have a therapeutic effect. As a result, the drug passes through the digestive tract through and through without being absorbed. The absorption of antibiotics is reduced in such cases by 20-80%, that is, their effect is close to zero.

Calcium caseinate also prevents the absorption of LINCOMYCIN HYDROCHLORIDE. Milk neutralizes the action of potassium and antacids (enzymes to improve digestion), reducing the acidity of gastric juice.

It is impossible to drink medicines with an acid-resistant shell (PANCREATIN, BISACODIL) with milk, as the coating will dissolve prematurely and the drug will collapse before reaching the intended absorption site.

Drinking ASPIRIN with milk, you completely neutralize its therapeutic effect. The milk simply curdles the Aspirin and it precipitates.

Acidic foods and tonic drinks

When prescribing antibiotics, you should be very careful about your diet. “Acid” foods should be excluded from it: fruits, juices, sodas and any dishes prepared with the addition of vinegar.

Many drugs combined with tonic and carbonated drinks are not absorbed by the body. The reason is that these drinks often contain phosphoric acid and other chemical compounds (iron and calcium ions, etc.), which react with the active substances of the tablet. First of all, this concerns:

antacids (to improve digestion);
diuretic DIAKARB (diuretic);
preparations of CALCIUM;
antibiotics (ERYTHROMYCIN, SUMAMED, RULID, LINCOMYCIN, DALATSIN).

Alcohol increases the side effects of drugs, up to death

Ethyl alcohol changes the permeability of cell membranes. Due to this, the effect of all drugs, except antibiotics, is enhanced - as are their side effects. One should not hope that this method will help to reduce the dosage of an expensive drug: the load on the liver increases faster than the intended effect, and very quickly reaches dangerous limits.

Beer (including non-alcoholic) contains substances that inhibit the work of liver enzymes. Because of this, drugs are processed more slowly than the manufacturer intended, which also increases the risk of overdose.

Consequences: nausea, vomiting, headache. There are side effects of the drug, which was taken along with alcohol. There may be a malfunction in the liver, gastric bleeding.

Never mix alcohol and painkillers - this can lead to serious liver problems or stomach bleeding. It is strictly forbidden to combine antidepressants and alcohol: the bad consequences of unpredictable strength will affect not only the liver, but also the brain.

Drugs and alcohol in any form do not mix. At the time of treatment, all types of alcohol are prohibited.

This also applies to the hangover syndrome: at this time, it is unacceptable to take conventional painkillers that relieve headaches. For safety reasons, it is better to use other methods of dealing with a hangover that do not cause side effects.

For example if:

INSULIN + alcohol = hypoglycemic coma
Blood pressure medication + alcohol = circulatory collapse (loss of consciousness)
PARACETAMOL + alcohol = liver damage

The most famous victim was Antonio Benedi, an aide to US President George W. Bush. Once he had a cold and took 10 paracetamol tablets for 4 days. This is a standard therapeutic dose, but in combination with alcohol it is an explosive mixture, due to which the liver can “fail”. Not knowing this, Benedi remained true to one of his old habits - drinking 3-4 glasses of noble wine for tone and health. As a result, to save his life, he had to do an emergency liver transplant.

ASPIRIN + alcohol = gastritis, peptic ulcer.

What is the best way to take medicine?

When taking the medicine, you must adhere to the basic rule: if the doctor did not specify the features of taking the tablets, it is best to drink them with boiled water.

For these purposes, water at room temperature (about 20 degrees) is suitable. Water is a chemically neutral substance, which means it is a universal liquid.

Drink only water should be the following drugs:

drugs in gelatin capsules;
antiulcer drugs (DE-NOL, GASTROPHARM, etc.);
preparations of the tetracycline and lincosamide group (with plenty of fluids and better standing).

To drink a pill or capsule, ¼ cup is enough, and only in special cases (for example, while taking salicylates, antibiotics), more liquid may be required - at least a glass.

Liquids for special occasions

To achieve the desired effect, individual drugs are recommended to drink not with water, but with a well-defined liquid.

drugs that irritate the gastric mucosa, while not binding to milk proteins and calcium;
anti-inflammatory and analgesic drugs (for example, INDOMETACIN, RESERPINE);
some hormonal drugs;
preparations of iodine;
anti-tuberculosis drugs ETIONAMIDE and PROTIONAMIDE.

Sometimes drugs are recommended to drink alkaline drink(mineral water or water like Borjomi), this accelerates the transition of the medicinal substance from the stomach to the intestines and promotes rapid absorption and, therefore, the fastest therapeutic effect.

These drugs include:

ERYTHROMYCIN, which is taken only on an empty stomach and washed down only with alkaline mineral water, because the acidic environment of the stomach destroys it.
BISEPTOL, SULFADIMETOXIN and the entire group of sulfanilamide drugs (for example, STREPTOCID, SULFADIMETOXIN, NORSULFAZOL, FTALAZOL, ETAZOL), as well as ANALGIN, should be washed down with alkaline mineral water, which promotes the fastest absorption of the drug in the intestine.
ASPIRIN (note that one hour before taking ASPIRIN, you should not eat spicy food and citrus fruits, otherwise you will not be able to avoid irritation of the mucous membrane).

Sometimes drugs are taken kissel:

ASPIRIN and other drugs containing acetylsalicylic acid are best taken after meals, or washed down with something enveloping, such as jelly or rice water. The role of the mucus jelly is to reduce the contact time of this type of drug with the contents of the stomach and protect its mucosa.

It may seem difficult to remember what you can and cannot drink this or that medicine with. But in fact, there is nothing complicated. It is enough to read the instructions (all the necessary information can be found in the description of the drug, that is, in its annotation) or ask the attending physician, and if it is not possible to do this, then drink the medicine with water and you will definitely not be mistaken.

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Based on materials: IFC Pharmacy, MED Encyclopedia, Russian Pharmacy Magazine.

Tablets can not be washed down with tea, you need to figure out what effect the drink has on the body. Tea is not the only drink that is not recommended to drink medicines. There are also features of the combination of medicines and drinks.

Tea and more: drinks that should not be washed down with pills

Drinks that should not be washed down with medicine:

Each of them has its own negative effect on the body when combined with a medicine. Caffeine, which is found in coffee and tea, is the strongest stimulant, so it is not recommended to mix it with other stimulants.

Tea also contains a chemical compound - tannin, which is able to suppress the beneficial effects of therapeutic agents. Coffee and tea can increase the effect of drugs or, on the contrary, slow it down. Especially unpredictable consequences can be if a woman drinks contraception with tea.

Juices and sodas contain citrates. These compounds are not combined with drugs that are supposed to reduce the acidity of the gastric juice. Combining the juice with a medicinal product will further reduce the acidity and interfere with the action of sedative drugs with antibiotics.

Aspirin should not be drunk with citrus juice, because they can cause ulcers due to excessive irritation of the mucosa. Cranberry juice is not compatible with anticoagulants. Useful in itself, grapefruit juice, along with tablets, will double their effect, which can lead to an overdose. This is dangerous with heart drugs, antidepressants and antibiotics.

In no case should the medication be combined with drinking alcohol. For various reasons, it does not correlate with many drugs. Mixing beta-blockers and clonidine with alcohol can lower blood pressure and cause unconsciousness. If you mix alcohol with anticoagulants, it will lead to an overdose and may cause a stroke. Drinking alcoholic beverages along with insulin and diabetic drugs can put a person into a diabetic coma.

How to drink medicines?

It is most correct to drink medicines with ordinary boiled water. If there are no special instructions in the instructions, it is best to drink water. To drink a dietary supplement, it is permissible to take juice (but not grapefruit).

Mineral water may not always be useful, because it interferes with the action of the medicine. But mineral water with a high level of alkali can be washed down with non-steroidal anti-inflammatory drugs such as aspirin. For drugs that can cause irritation of the mucous membrane, it is permissible to use milk.

The presence of caffeine is the main reason why tablets should not be taken with tea, but there are restrictions for most others. In addition, there are recommendations on the time of use of different types of drugs and the required amount of water.

Not everyone carefully read the attached instructions before taking the medicine. But it is especially important to familiarize yourself with the part where tips for use are prescribed. Many people think that tablets can be taken with any drink. But often the wrong combination of the drug and the drink can reduce the medicinal properties of the drug. Therefore, you need to know how to drink pills. A detailed answer to the question is presented in the article.

Dosage forms

Preparations intended for oral administration have different forms. They are produced in the form of tablets, capsules, solutions, tinctures, infusions, dragees, pills, powders. The form affects the rate of absorption of the active ingredient.

The most effective medicines are tablets. But they are not the same: some have a “glaze” shell, while others are produced without it. Such a coating is usually present when the tablet contains components that are aggressive to the stomach, or when the active substance needs to be protected from splitting by gastric juice. Cleavage of coated tablets occurs in the intestine.

There are drugs that have a multilayer protective coating. They have a long-term effect, since the active ingredient is released gradually. Glazed tablets should not be crushed or crushed, as the active ingredient is released prematurely with the destruction of the protective film.

Any tablets are required to be taken. This makes it easier to swallow, and also leads to the dissolution and absorption of the drug. Usually the instructions indicate which drink is better to use for this. In order for the drug to work and not cause side effects, you need to know how to drink tablets of different types. According to reviews, it is important to take into account the opinions of experts.

Water for drinking

Can the tablets be taken with water? Sometimes there are no special notes on this issue in the instructions. Then you can choose ordinary water at room temperature: boiled or bottled, but without gas. It has the property of a solvent, but the formula of the drug does not change with it. According to reviews, many people use water for drinking. It is the safest type of liquid and is suitable for most medications.

You need to drink as much liquid as indicated in the annotation. Especially in the instructions, it is recommended to drink at least ½ glass of liquid, and not 1-2 sips. When there is not enough water, the tablet will not be dissolved in the stomach in a timely manner and will not begin to act. As a result, the body will not receive the entire portion of the active ingredient, but only a part of what is in the preparation. Can you take the pill with sparkling water? This will be discussed in the next section.

What kind of water is suitable?

You can take pills. Do not do this. But should you take the tablets with mineral water? Doctors note that there are warnings here. There are a lot of salts in such a liquid that are able to participate in reactions with the active ingredient or tablet shell.

Alkaline mineral water is suitable for Aspirin, Streptocide, Phthalazole. Due to the alkaline environment, the duration of the product increases, and the removal of toxins is simplified. If "Analgin" or "Tetracycline" will be washed down with alkaline water, then the dosage must be controlled, since the absorption of drugs increases due to such water. Bottled water is now on sale, which is ideal for drinking pills.

Therefore, it is not worth drinking the tablets with carbonated water, but non-carbonated or mineral water is just right. And Cola and sweet pops are not the best choice. Soda irritates the gastric mucosa, and when combined with drugs, this effect is enhanced. When using "Cola", the therapeutic effect of many drugs is noticeably reduced.

Tea

It is better not to drink tablets with tea. This is due to the fact that a drink made from tea leaves includes phenolic compounds from tannins (there are also in red wine). Why can't you take pills with tea? Phenolic components are incompatible with codeine, aminophylline, cardiac glycosides, since absorption is impaired with them.

Tea should not be consumed if iron medications are being taken as the mineral will not be absorbed. At different times, this drink and antibiotics, stomach and cardio drugs should be taken. Is it possible to curl antidepressant pills with tea? This combination leads to symptoms of overexcitation. And contraceptives won't work.

Coffee

What to take the pills besides water? Many people think that black coffee is suitable for this, they do not think about the consequences. This drink is incompatible with many drugs, as it reduces their effectiveness. This applies to vitamins, in particular, vitamin C, whose beneficial properties disappear due to coffee. The drink should not be combined with homeopathic remedies, as they will not work.

There is another reason why you should not drink coffee - this is the diuretic effect of the drink. The medicine will be quickly removed from the body without having time to act. But there are times when coffee enhances the effect of a medicine. This happens with pain medications that contain caffeine. But then there is a risk of drug overdose.

It will not be effective to take drugs that regulate blood pressure, heart function. It is also a threat to the diseased cardiac system. You should not drink sleeping pills with coffee, because the result will still not be.

Milk

It is widely believed that it is useful to drink a tablet with milk, since the product serves as a protection for the walls of the stomach from irritation. Sometimes this drink is combined with medicines. For example, with acetylsalicylic acid, non-steroidal drugs, fat-soluble vitamins (A, D, E, K), iodine-containing, anti-tuberculosis and some hormonal drugs.

But there is a list of drugs that are not combined with this drink. Can you take cardiac glycosides tablets with milk? To preserve the therapeutic effect, this is not worth doing. Another drink is not combined with caffeine-containing drugs, drugs for the treatment of ulcers, enzymes. Due to milk, the action of tetracycline, penicillin, cephalosporin antibiotics is lost. Due to their reaction with calcium, a substance appears that cannot be absorbed by the body, so there will be no effect from taking the remedy. Also, milk should not be consumed with iron-based preparations. This is also due to calcium, which prevents iron from being absorbed.

Tablets with an acid-resistant coating are not compatible with milk. These drugs have a special shell that protects against destruction by gastric juice. These drugs only work in the intestines. If you drink this remedy with milk, it will dissolve in the stomach, and the active ingredient will not enter the intestines, so there will be no result from the treatment. Often, manufacturers indicate how to drink pills, and what is better not to use.

Juices

Can I take the pill with juice? Many believe that if this drink is useful in itself, then when combined with drugs, there will only be benefits. But this is an erroneous opinion.

Vegetable and fruit juices can both reduce and enhance the therapeutic effect of certain drugs. For example, Ampicillin, Azithromycin, Erythromycin lose their effect when combined with this drink. And "Aspirin", "Paracetamol", "Ibuprofen" and nitrouranium products with acidic and vegetable juices enhance the effect.

If sulfanilamide is combined with tomato juice, then the antibacterial effect of the drug will noticeably decrease. The reason is the reaction with folic acid, which is in the drink. Another medicine of this group should not be washed down with acidic drinks. These are alkalis. There will be a chemical reaction between the substances, due to which the effect of the drug is leveled.

Psychostimulants should not be combined with pineapple or grape juice. This can lead to a hypertensive crisis. The combination of antacids and acidic juices is controversial. Medicines of this group protect the gastric mucosa from irritation with hydrochloric acid and bile. And fruit acids, which are in acidic drinks, lead to the destruction of the protective layer on the walls of the stomach, and an increase in acidity in it.

Preparations with warfarin should not be washed down with cranberry juice, otherwise negative consequences are likely. The berries contain components that thin the blood. Due to an overdose of components, bleeding may occur.

According to doctors, the combination of tablets with grapefruit juice is dangerous. This is due to the fact that the drink contains various components that affect the enzymatic work of the liver, which is why the chemical components can have an unpredictable effect. Grapefruit juice should not be combined with heart medications, antidepressants, antibiotics, anti-allergy, anti-fungal, or anti-virus medications, or medications that lower blood pressure. Acidic juices are not used to drink coated tablets, as this is dangerous for the digestive system.

Compote or jelly

Many people like drinks such as jelly and compote. They are tasty and healthy. Compotes contain vitamins and other nutrients, and jelly has an enveloping effect, which has a positive effect on gastritis or stomach ulcers.

Although drinks are useful, they should not be combined with medical products. If the tablet is washed down with jelly, then the therapeutic effect will noticeably decrease. Compote, saturated with fruit acids, changes the pharmacological action of drugs, especially those that treat hypertension, heartburn.

Alcohol

No alcohol should be combined with drugs. Such drinks not only neutralize the therapeutic effect. Alcohol also leads to chemical reactions, due to which there are severe poisoning, violations of the functions of internal organs and the psyche. For example, many cough or headache remedies contain codeine, which reacts with ethanol to cause respiratory depression. If a glass of wine is drunk on the date of taking the drug with codeine, then it is advisable not to take the pill.

It is dangerous to combine alcohol with sleeping pills, antidepressants, analgesics, antibiotics, antipyretics and antiallergic drugs, since ethanol enhances the effect of these drugs and significantly increases the load on the liver.

With the regular combination of alcohol with "Aspirin", a stomach ulcer may appear. And means for lowering blood sugar can lead to hypoglycemia. Soluble cold preparations with ethanol increase blood pressure.

Features of the absorption of tablets

To ensure a therapeutic effect, the drug must enter the bloodstream. And for this, the active ingredient is absorbed through the walls of the stomach or intestines. A strong effect on this process has an acidic environment, which is different in different places of the digestive tract. Acid preparations are usually absorbed in the stomach, while alkaline preparations are absorbed in the intestines.

Another test that the drug passes in the body is considered to be Many drugs, when in contact with food enzymes, lose their effect. This applies to protein and polypeptide components, such as insulin and vasopressin. Some hormonal agents cannot act with enzymes.

There are tablets that are not swallowed, but dissolved in the mouth. This method of administration allows the main component to quickly enter the bloodstream without passing through the liver. These are not all factors affecting the absorption and effect of drugs. Food is important, which affects the formation of gastric juice and enzymes in different ways, which affects the absorption of the tablet.

When is the best time to take the tablets?

If there are no special instructions in the instructions for the medicine, this does not mean that it can be taken at any time. Usually tablets are taken 20-30 minutes before meals, when the active ingredient is easier to digest.

If an acid-base environment is required for its absorption, then the exact period of taking the drug is indicated in the instructions. Often, food intake affects the duration of the medicine.

For half an hour, the reception is supposed to:

drugs that act on the formation of gastric juice;
hormonal agents;
preparations based on live bacteria;
homeopathic medicines;
decoctions of medicinal herbs.

During the meal, enzymes are taken that improve the absorption of products. There are remedies to be taken after meals. This applies to most medications, drugs that irritate the gastric mucosa, vitamins and dietary supplements.

Thus, different drinks are used to drink tablets. This information must be sought in the instructions for a particular tool. Taking into account the recommendations presented in the article will make the effect of any drug more effective.

Our expert - doctor-therapist, candidate of medical sciences Alexandra Shnurova.

Often, in order to take a pill, we take the liquid that is at hand at the moment. But in vain. After all, the chemicals contained in various drinks can react with the components of drugs. As a result, the drug can not only lose its effectiveness, but also be toxic to the body.

Water, but not

The general rule is that medicines should be washed down with boiled water at room temperature. And although there are exceptions to any rule, nevertheless, other drinks should be used only if this method of consumption has been recommended by the attending physician. Therefore, unless your doctor specifically stipulates this item, use drugs only with plain, filtered and boiled water.

Even mineral water is not always suitable for this purpose - it can interfere with the absorption of certain drugs. However, non-steroidal anti-inflammatory drugs, aspirin, analgin, many sedatives, iodine preparations and other drugs that irritate the gastric mucosa, it is even useful to drink mineral water with a high alkali content. But in no case should you use sweet soda for this. No matter how great the desire to sweeten the bitter pill is, it is better to refrain from this method - since insoluble compounds form in the body from such a combination.

Dangerous acid

There are drugs that work most effectively with acidic juice (for example, aspirin, paracetamol, anti-tuberculosis drugs), but for most drugs this neighborhood is detrimental. For example, it is known that acid destroys calcium preparations, neutralizes the effect of antibiotics and many other drugs.

Fruit juices, especially acidic ones, negate the effect of taking antacids that reduce the acidity of gastric juice. Do not drink acidic juice or compote with cardiac glycosides and sulfonamides - drugs that are also alkalis. It is especially dangerous to combine pills with grapefruit juice, as this "hellish mixture" causes many adverse reactions. This tasty and healthy drink, when consumed together with medicines, is able to activate their action by 2 times. This is how people often overdose on heart medications, as well as antidepressants and antibiotics, medicines designed to lower blood pressure and regulate cholesterol levels and heart rate. Therefore, people, especially the elderly and not very healthy, who are forced to regularly take strong medicines (for example, heart medications), it is better to forget about grapefruit juice forever.

Maybe a seagull?

Using coffee and tea for the quickest swallowing of medicines is also not useful. Firstly, the tannins found in these drinks, when interacting with the components of many preparations, form a precipitate. Secondly, this combination can have a bad effect on the heart. In particular, this applies to nitrogen-containing drugs: papaverine, codeine, caffeine, aminophylline, cardiac glycosides.

The effect of coffee on drugs is even more unpredictable than that of tea. In some cases, it inhibits the action of drugs, while in others, on the contrary, it enhances the effect. So, while taking painkillers such as citramone and aspirin and large portions of coffee, the condition of the liver and other organs may worsen.

However, the wrong combination of medicine and drink will not necessarily lead to poisoning, but may simply reduce the expected effect of the drug. Which in the case of, for example, oral contraceptives is not so harmless. It is known that, drinking contraceptive drugs with tea or even a decoction of medicinal herbs (for example, St. John's wort), you can achieve not quite the effect that you expected.

Milk should not be taken with anti-ulcer drugs (cimetidine, ranitidine), heart medications, iron preparations, enzymes and some antibiotics. At the same time, the fat contained in this wonderful product contributes to better absorption of fat-soluble vitamins (D, E, K, A), iodine preparations, as well as indomethacin or reserpine.

How not to drink to health?

Of course, it is hardly necessary to elaborate on the fact that it is very harmful to use drugs along with alcohol. This is already obvious, because ethyl alcohol, which is part of alcohol, is in itself a rather aggressive active substance. Therefore, it either conflicts with the equally active ingredients of the drugs, or enhances their effect. Therefore, in combination with alcohol, drugs (especially antibiotics) usually become toxic.

Taking alcohol along with anticoagulants prescribed for the threat of blood clots can even lead to a stroke. However, still few of the sane people would think of drinking pills with vodka. But it turns out that in order to get drug poisoning, it is not necessary to do this. It is enough to drip vasoconstrictor drops into the nose, and then go to a party. And even if you drink only one mug of beer or a small cocktail in a warm company, then all the symptoms of a severe hangover in the morning, and maybe even earlier, will be guaranteed to you. And the thing is that alcohol in combination with such drugs dramatically increases blood pressure. Up to a hypertensive crisis.

Admission rules

Many people remember how, in childhood, mothers and grandmothers crushed them between two tablespoons of tablets into powder. It turns out that this should be done not only to make it easier to swallow a large pill. By crushing the tablet, you can reduce its irritating effect and accelerate the absorption of active substances by the body. You can’t just do this trick with capsules and tablets coated with a protective shell. After all, the top layer of such drugs specifically serves to ensure that they reach the stomach unharmed. "Effervescent" tablets, before drinking them, must be dissolved in the amount of water indicated in the instructions.

Most drugs are taken on an empty stomach, since the gastric juice released during eating has a destructive effect on a number of drugs. But many medicines are indicated to be taken strictly before or after meals. For example, enveloping and choleretic agents that help with ailments of the gastrointestinal tract are taken before the start of the meal.

During meals, they drink enzyme preparations that help to properly digest food, as well as some diuretics and fat-soluble vitamins A, D, E. Anti-acid drugs are recommended to be taken after meals. However, by and large, it is not necessary to memorize all these complex rules for taking medications, since it is necessary to use specific drugs strictly according to the instructions indicated on the insert for the drug, and in accordance with the doctor's recommendations.