Xylene is a quick help in treating runny nose in children. Xylene (drops) - instructions, use, indications, contraindications, action, side effects, analogues, dosage, composition

There are many drugs on the pharmaceutical market that are used to treat various otolaryngological diseases in children. These are various aerosols, drops, gels, solutions. Xylene is considered one of the effective drugs. This medicine in the form of a spray or nasal drops belongs to the group, so it quickly helps eliminate many symptoms of ENT diseases.

However, it is important to know the specifics of using Xylene in childhood. This will help prevent the development of side effects, as well as avoid cases of overdose.

Xylene contains xylometazoline hydrochloride, which is the active substance of the drug. The auxiliary components of the drug include:

• Sodium hydrogen phosphate
• Potassium dihydrogen orthophosphate
• Trialon B
• Benzalkonium chloride
• Sodium chloride
• Purified water

The combination of these substances in Xylene has vasoconstrictor properties. Thanks to this, it has the following effects on the body:

• Prevents swelling of the nasal mucosa.
• Reduces hyperemia.
• Eliminates nasal congestion.
• Facilitates nasal breathing.
• Helps reduce rhinorrhea.

These properties are indispensable in the treatment of otolaryngological pathologies, therefore they are often prescribed in ENT practice.It is important to say that the effect of using the drug is observed after about five minutes and lasts up to ten hours.

In pharmacies you can buy Xylen in the following two forms:

• Nasal drops
• Spray for intranasal use

The drops are contained in dark glass bottles. Kislen is also available in polymer containers. These bottles are in cardboard packages. The box also contains special nozzles for instilling or spraying the medicine.

Depending on the age of patients it is intended for, the content of the active component in the drug is different. For children under six years of age, Xylen is prescribed at 0.05 percent.

Older children are prescribed drops and spray with a 0.1 percent concentration of the substance.

The instructions indicate that Xylene is good for three years from the date of manufacture. Then the medicine loses its properties and has no therapeutic effect.

When is Xylen prescribed to children?

Due to its actions, the drug is popular in the treatment of ENT diseases. It is prescribed to both adults and children.

Xylen is usually prescribed in childhood for the following diseases:

• in acute form
• Hay fever
• Sphenoiditis
• Rhinitis of allergic etiology

For otitis media, you also need to put drops in your nose, not your ear canals. There is an opinion that Xylen can be used as eye drops, but the instructions do not include eye diseases as an indication; on the contrary, it is not recommended to use the drug for patients with glaucoma.

It is also recommended to use the drug for heavy nasal discharge and nasal discharge, which are a sign of various respiratory and viral diseases.Xylene is used after nasal surgery and before certain medical procedures, such as rhinoscopy.

Dosage and application features

Xylene is used only intranasally.0.1 percent nasal drops are used to treat patients aged six years and older. The recommended dosage in this case is one to two drops in each nasal passage up to three times a day.

If Xylene is used in the form of a spray to treat a runny nose, then one injection into each nostril will be sufficient. The interval between doses should be at least eight hours. A 0.05 percent spray is used one to two times a day.

After using Xylene, you must rinse the spray nozzle and close the bottle with a lid.

The maximum duration of treatment is up to a week in adults. Children should be treated with Xylen for no longer than five days. This is explained by the fact that the drug can provoke addiction, which may result in the development of undesirable health consequences.

A special feature of nasal instillation with Xylen is preparation for the procedure. To do this, you must first clear the nasal passages of secretions. Therefore, it is important to blow your nose before using nasal drops, and then rinse. You can rinse your nose with a salt solution you prepare yourself. The pharmacy also sells products based on sea water for this procedure: Physiomer, Humer and others.

Nasal drops have a number of restrictions for use. Patients who suffer from the following diseases are not allowed to use the product:

• Atherosclerosis in an advanced stage
• Hypertension
• Glaucoma of various origins
• Atrophic rhinitis
• Tachycardia

A contraindication to the use of Xylene is individual hypersensitivity to any components of the drug. Also, drops are not prescribed to patients who have undergone surgical interventions affecting the lining of the brain.

Due to the incompatibility of the drug with antidepressants, as well as with monoamine oxidase inhibitors, Xylene is not prescribed for simultaneous treatment with drugs of this group. The interval between therapy with these drugs should be at least fourteen days.Caution when using this medication is important for people who have a history of diabetes mellitus, angina pectoris, hyperthyroidism and prostate adenoma.

Possible adverse reactions and overdose

Typically, Xylen nasal drops are tolerated normally by patients. But sometimes if the rules of use are violated, the following side effects may occur:

• Dry mucous membranes
• Sneezing
• Increased swelling
• Copious mucous discharge
• Burning and tingling sensation in the area where the drug was injected
• Sleep disorder

In rare cases, organ system disorders occur. These include migraine, high blood pressure, arrhythmia, decreased vision, tachycardia, depression, and vomiting. Typically, such phenomena are observed when the instructions for use of Xylene are not followed (exceeding the dose and amount of daily use).

It is important to say that if Xylen is treated for more than five days, then addiction to the active component is possible, which can provoke drug-induced rhinitis.

An overdose is possible when the dosage and daily amount of drops or spray are violated during treatment. Possible symptoms of overdose include:

• Blood pressure instability
• Convulsions
• Development of depression
• Increased heart rate

More information on how to treat a runny nose in a child can be found in the video:

There is no specific antidote to the drug substances. In order to eliminate such reactions, you need to contact a specialist. Usually in such cases he will prescribe remedies that eliminate these symptoms. Often these are drugs that stabilize the functioning of blood vessels and the heart.

In this article you can read the instructions for use of the drug Xylene. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Xylene in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Xylene in the presence of existing structural analogues. Use for the treatment of allergic rhinitis and sinusitis in adults, children, as well as during pregnancy and lactation. Composition and addiction to the drug with long-term use.

Xylene- a vasoconstrictor for local use in ENT practice. Alpha adrenergic agonist. When applied to the mucous membranes, it causes vasoconstriction, as a result of which local hyperemia and swelling are reduced. For rhinitis, it facilitates nasal breathing.

Compound

Xylometazoline hydrochloride + excipients.

Pharmacokinetics

When applied topically, it is practically not absorbed; plasma concentrations are so small that they cannot be determined by modern analytical methods.

Indications

• acute allergic rhinitis;
• sinusitis (sinusitis);
• hay fever;
• otitis media (to reduce swelling of the nasopharyngeal mucosa);
• preparing the patient for diagnostic procedures in the nasal passages.

Release forms

Nasal drops 0.05% and 0.1%.

Nasal spray 0.05% and 0.1%.

Instructions for use and dosing regimen

Apply topically for 7-14 days. The dose depends on the dosage form used and the age of the patient.

Side effect

• irritation of the mucous membrane, burning, tingling;
• sneeze;
• dry nasal mucous membranes;
• hypersecretion;
• swelling of the nasal mucosa (more often with long-term use);
• heartbeat;
• heart rhythm disturbances;
• increased blood pressure;
• headache;
• vomit;
• sleep disorders;
• visual impairment;
• depressive state.

Contraindications

• angle-closure glaucoma;
• atrophic rhinitis;
• arterial hypertension;
• tachycardia;
• severe atherosclerosis;
• hyperthyroidism;
• surgical interventions on the meninges (history);
• hypersensitivity to xylometazoline.

Use during pregnancy and breastfeeding

During pregnancy and lactation, it should be used only after a thorough assessment of the risk-benefit ratio for the mother and fetus; recommended doses should not be exceeded.

Use in children

Xylometazoline should be prescribed with caution to children under 2 years of age (gel - up to 7 years).

special instructions

It should not be used for a long time, for example, with chronic rhinitis, as addiction or dependence may develop. For colds, in cases where crusts form in the nose, it is preferable to administer it in the form of a gel.

Drug interactions

Incompatible with MAO inhibitors and tricyclic antidepressants.

Analogues of the drug Xylen

Structural analogues of the active substance:

• Brizolin;
• Galazolin;
• Grippostad Reno;
• For nose;
• Dr. Theiss Nazolin;
• Dr. Theiss Rhinotheiss;
• Asterisk NOZ;
• Influrin;
• Xylobene;
• xylometazoline;
• Xymelin;
• Xymelin Eco with menthol;
• Nosolin;
• Nosolin balm;
• Olint;
• Otrivin;
• Rinomaris;
• Rhinonorm;
• Rhinorus;
• Rinostop;
• Sanorin Xylo;
• Sialor;
• Snoop;
• Suprima NOZ;
• Tizin Xylo;
• Tizin Xylo Bio;
• Farmazolin;
• Eucazoline Aqua;
• Espazolin.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.

Xylene (active ingredient - xylometazoline) is a local vasoconstrictor from the group of alpha-adrenergic agonists for use in otolaryngological practice to facilitate nasal breathing. The nose, along with the throat, actually serves as an entry gate for infection to enter the body. It is the nasal cavity that is the very “Brest Fortress” that takes the main viral-bacterial “artillery” blow. In this regard, one of the most pressing issues in the autumn-winter period should be considered the relief of cold symptoms and improving the quality of life if the infection has not passed you by. The reason for the surge in acute respiratory infections is a number of factors, including the accumulation of “sneezing and coughing” masses of people in enclosed spaces, hypothermia, seasonal weakening of the immune system, the functioning of the heating system, etc. Thus, central heating contributes to a catastrophic decrease in humidity, as a result of which the mucous membrane of the nasal cavity dries out, its blood supply deteriorates and makes it more defenseless for viral and bacterial infections. All this greatly increases the chances of pathogenic microorganisms safely passing the mucous membrane of the nasal cavity and oropharynx and systemically penetrating the body. The first alarm bells of an infection are rhinorrhea, swelling of the nasal mucosa and difficulty in nasal breathing - in other words, everything that is popularly called a runny nose, and in the international classifier of diseases - acute rhinitis. Despite all the unpleasantness of its manifestation, it is necessary to point out that by running the nose and sneezing, the body tries to protect itself from foreign particles. The secretion secreted by the mucous membrane contains immune system factors such as the enzyme lysozyme and leukocytes. They protect the body from viral and bacterial invasion. Against the backdrop of a developing disease, the nasal mucosa is forced to literally work for wear and tear. Blood vessels dilate to allow air in the nasal passages to warm up more quickly and transport white blood cells to their destination.

As a result, swelling of the mucous membrane develops, which causes the same difficulty breathing characteristic of a runny nose. To more effectively remove foreign agents, mucus production increases significantly. Thus, during rhinitis, the human nasal mucosa is capable of producing about 1.5 liters of mucus per day. However, it is obvious that it is quite difficult to sit with your hands folded when it is pouring from your nose like a bucket, and you can only breathe through your mouth. In this regard, the pharmacological industry has created a huge number of drugs that can relieve cold symptoms and facilitate nasal breathing. One of these drugs is the domestic anticongestive drug xylene. When it comes into contact with the mucous membrane of the nasal cavity, it causes vasoconstriction, as a result of which the blood flow to its inflamed areas decreases and the swelling resolves. When applied topically, xylene is practically not absorbed into the systemic circulation, which minimizes its side effects. Moreover, the concentrations of xylometazoline, the active ingredient of the drug, are so low that they cannot be determined by modern analytical methods.

Xylene is available in two dosage forms: nasal drops and spray. The duration of use of the drug is on average from 7 to 14 days. The specific therapeutic dose is determined by the dosage form currently used and the age of the patient. Xylen should be prescribed with caution in children under 2 years of age. The same applies to pregnant or lactating women, who can use the drug only in cases where the expected benefit to the mother outweighs the potential risks to the child or fetus. The drug is not recommended to be taken for a long period of time, for example, when rhinitis has become chronic. Xylene is incompatible with monoamine oxidase inhibitors and tricyclic antidepressants.

Pharmacology

Vasoconstrictor for local use in ENT practice. Alpha adrenergic agonist. When applied to the mucous membranes, it causes vasoconstriction, as a result of which local hyperemia and swelling are reduced. For rhinitis, it facilitates nasal breathing.

Pharmacokinetics

When applied topically, it is practically not absorbed; plasma concentrations are so small that they cannot be determined by modern analytical methods.

Release form

10 ml - polymer bottles (1) - cardboard packs.

Dosage

Apply topically for 7-14 days. The dose depends on the dosage form used and the age of the patient.

Interaction

Incompatible with MAO inhibitors and tricyclic antidepressants.

Side effects

With frequent and/or prolonged use: irritation of the mucous membrane, burning, tingling, sneezing, dry nasal mucosa, hypersecretion.

Rarely: swelling of the nasal mucosa (more often with long-term use), palpitations, heart rhythm disturbances, increased blood pressure, headache, vomiting, sleep disorders, visual disturbances.

With long-term use in high doses: depressive state.

Indications

Acute allergic rhinitis, sinusitis, hay fever, otitis media (to reduce swelling of the nasopharyngeal mucosa), preparing the patient for diagnostic procedures in the nasal passages.

Contraindications

Angle-closure glaucoma, atrophic rhinitis, arterial hypertension, tachycardia, severe atherosclerosis, hyperthyroidism, surgical interventions on the meninges (history), hypersensitivity to xylometazoline.

Features of application

Use during pregnancy and breastfeeding

During pregnancy and lactation, it should be used only after a thorough assessment of the risk-benefit ratio for the mother and fetus; recommended doses should not be exceeded.

Use in children

special instructions

Should not be used for a long time, for example, for chronic rhinitis. For colds, in cases where crusts form in the nose, it is preferable to administer it in the form of a gel.

Use in pediatrics

Xylometazoline should be prescribed with caution to children under 2 years of age (gel - up to 7 years).

Xylene is a drug for local use from the group of alpha-adrenergic agonists; it has a vasoconstrictor effect when applied to the nasal mucosa, reduces swelling and local redness, and generally makes nasal breathing easier.

What is the composition of the medicine Xylene (drops)?

The drug Xylene is available in nasal drops in concentrations of 0.1 and 0.05%. 10 milliliters of medicine are placed in a container represented by a polymer dropper bottle. In addition, a bottle of tinted glass is available, which comes with a dropper attachment.

The medicine Xylene contains the active substance represented by xylometazoline hydrochloride, in addition, some auxiliary ingredients are present in the solution. The storage temperature of the medication varies from fifteen degrees to 25. The shelf life is three years, after this time it is necessary to refrain from further use of the medication.

What is the effect of the drug Xylene (drops)?

The vasoconstrictor Xylen is used topically in the practice of ENT doctors. Under the influence of the active component, the blood vessels in the nasal cavity narrow, which leads to the removal of swelling, in addition, the severity of redness of the mucous membrane decreases, as a result, nasal breathing noticeably improves, which is important if the patient has rhinitis.

When used topically, the drug is not absorbed; as a result, the concentration of the active component of the drug in the plasma is so minimal that it cannot be determined by modern methods.

What are the indications for use of the medicine Xylene (drops)?

The instructions for use of the drug Xylene allow it to be prescribed for, when identified, when, it is an effective remedy for, since there is a decrease in swelling of the mucous membrane lining the nasopharynx.

In addition to the listed indications, the drug Xylen is used before preparing the patient for diagnostic procedures that are planned to be carried out in the nasal passages.

What are the contraindications for use of Xylene (drops)?

The instructions for use prohibit the use of Xylene (drops) for treatment in the following cases:

With previous interventions on the membranes of the brain;

Do not use the product for;

In addition, vasoconstrictor drops are not prescribed to patients with diagnosed hyperthyroidism.

What are the uses and dosage of Xylen (drops)?

Xylen is used in drops locally; treatment procedures should last no more than one or two weeks. It is worth noting that the medicine is incompatible with tricyclic antidepressants, as well as with MAO inhibitors.

The drops are used intranasally, that is, they are instilled into the nasal cavity. Moreover, before each use of the medication, it is recommended to thoroughly clean the nasal passages of accumulated mucous contents. After the treatment procedure is completed, you need to wipe the dropper nozzle with a clean napkin, and then you need to tightly close the bottle with a lid.

Adults are usually prescribed the drug Xylene, one or two drops, which should be placed into the nasal passage; it is recommended to repeat this procedure twice or thrice throughout the day.

In pediatrics, the drug is usually used in 1 or 2 drops, while Xylene 0.05% is used, the medicine is instilled into the nose up to two times a day. The minimum interval between use of the medication should be eight hours.

What are the side effects of Xylen (drops)?

Xylene drops, which we continue to talk about on this page www.site, can have some side effects when used topically. They usually manifest themselves in the form of irritation of the mucous membrane, a burning sensation is observed, tingling is noted, the patient may complain of frequent sneezing, in addition, there is dryness of the nasal mucosa, and the development of hypersecretion is also possible.

With long-term use of Xylene nasal drops, swelling of the nasal mucosa can rarely develop, in addition, some systemic manifestations are added in the form of sleep disorders, arrhythmia is characteristic, blood pressure increases, headaches, blurred vision are observed, and a depressive state is also noted, in addition, possible dyspepsia in the form of vomiting.

special instructions

Xylen drops should not be used for a long time. Do not freeze the container with the medicine, since under the influence of low temperatures the effectiveness of the vasoconstrictor will be lost.

How to replace Xylene (drops), what analogues should I use?

Medicine Xylometazoline hydrochloride, Xylometazoline, Suprima-NOZ,

In the treatment of runny nose in adults, various vasoconstrictors, for example, Xylene, are in great demand. But is it possible to use such a drug in children and how to do it correctly so as not to harm the child?

Release form

Xylene is available in the form of drops and also as a spray. The drug is presented as a transparent liquid without color or with slight coloring.

Xylene nasal drops are sold in glass or plastic bottles with a capacity of 10 ml. The bottle can be equipped with a dropper cap or a pipette attached to it.

Xylen nasal spray is produced in polymer bottles or dropper bottles of different capacities. One bottle can contain 10, 15, 20 or 30 ml of the drug.

Compound

The main component in both Xylene drops and spray is a substance called “xylometazoline hydrochloride”. The 0.05% preparation contains 0.0005 grams per 1 ml, and each milliliter of the drug with a concentration of 0.1% contains 0.001 g. Additionally, Xylene contains disodium edetate, sodium chloride, benzalkonium chloride, sodium hydrogen phosphate dodecahydrate, potassium dihydrogen phosphate and purified water.

Operating principle

The active substance of any form of Xylene is an alpha-adrenergic agonist, used topically to constrict the vessels of the nasal mucosa. After entering the nasal cavity, the drug eliminates redness and swelling, which helps restore the patency of the nasal passages, as well as facilitate breathing through the nose.

Xylene begins to act 3-5 minutes after administration into the nose, and the effect of using the drug lasts up to ten hours. In this case, the medicine is almost not absorbed, so it enters the blood in a minimal amount.

Indications

Xylen is prescribed:

• For acute rhinitis, including allergic.
• For ARVI, the symptom of which is a runny nose.
• For nasopharyngitis.
• For sinusitis.
• For otitis media (as one of the means of complex treatment).

The drug is also used before rhinoscopy to facilitate such a diagnostic procedure.

At what age is it allowed to take

Treatment of children with a 0.05% solution of Xylene is permissible from 2 years of age, and a 0.1% drug can be used in children 6 years of age and older.

Use at an earlier age (for example, children under one year old) is possible only after a doctor’s prescription.

Contraindications

The drug is prohibited for use in patients with hypersensitivity to its components.

• Atrophic form of runny nose.
• Arterial hypertension.
• Glaucoma.
• Tachycardia.
• Having undergone surgery on the meninges in the past.

Very careful administration of the drug is indicated for diabetes mellitus and hyperthyroidism. In adults, the drug is contraindicated when carrying a child and breastfeeding, as well as atherosclerosis.

Side effects

If you use Xylene too often or for longer than recommended by the instructions, this will lead to dryness and irritation of the nasal mucosa, a burning sensation, increased secretion and frequent sneezing. In rare cases, administration of the drug into the nose leads to swelling of the mucous membrane, headaches, increased blood pressure, increased heart rate, vomiting, arrhythmia, sleep disturbances, depression or vision problems.

Another side effect of using Xylene is addiction. Some patients, after treatment with this drug and its discontinuation, experience nasal congestion and difficulty breathing through the nose. To eliminate this problem, it is recommended to dilute Xylen with saline and drip the diluted medicine, gradually reducing the concentration of the drug.

Instructions for use

Dosage

• After a doctor's prescription, infants and children under 6 years old are instilled with 0.05% Xylene drops in a dose of 1-2 drops in each nostril. The frequency of use of this form of medication is once or twice a day.
• For the treatment of children over 6 years old, use 0.1% medicine in drops in a single dosage of 1-2 drops for each nasal passage. You can bury your nose 2-3 times during the day. Often the medication is prescribed for 3-5 days.
• A nasal spray with a concentration of 0.05% is prescribed to children 2-6 years old (for example, at 4 years old) one spray per day. Sometimes your doctor may prescribe two nebulizations of this medication.
• A spray with a higher concentration (0.1%) is used in children over 6 years of age in a single dose of 1 spray. The frequency of administration of this form of Xylene into the nose is 2-3 times a day.

Cautions

When using Xylene in childhood, it is important to consider the following nuances:

• The child's nasal passages must be cleaned before administering the medication.
• The medicine should not be administered into the nose more than 3 times a day.
• The minimum interval between medications is considered to be 8 hours.
• If a dose is missed, Xylene should be instilled into the nose within an hour after the required time of administration. If more than an hour has passed, the medicine is not administered, and the next time the dose is not doubled.
• The duration of continuous use of the drug should not exceed 5 days.