Ruzam: medicine for allergies, instructions, price and analogues. A unique non-hormonal medicine for allergies Ruzam: instructions and price of a biologically active drug of protein nature Ruzam how to inject correctly

Allergies are one of the most common diseases that can occur with equal frequency in both children and adults. An allergic reaction most often manifests itself in the form of a rash, itching, burning and swelling of the skin, which brings discomfort to the patient. The instructions for use characterize the drug Ruzam as an effective remedy for the treatment of allergies.

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Composition, manufacturer and release form

Ruzam is produced in the form colorless solution, which is intended for subcutaneous injection. Packaged in glass ampoules, packed in aluminum foil blisters and cardboard packs. One package contains 5 ampoules of medicine with a dosage of 0.2 or 0.5 ml.

Allergy medicine

Composition of the drug:

• the main active ingredient is an extract from a culture of a thermophilic strain of Staphylococcus aureus;
• excipient – ​​phenol;
• sodium chloride solution.

The manufacturer of the drug is a Russian pharmacological company with the same name Ruzam-M. The product can be purchased at any pharmacy only with a doctor's prescription.

Medicinal properties

The instructions for use emphasize that Ruzam can only be used as prescribed by a doctor. This medicine belongs to antiallergic, anti-inflammatory and immunomodulatory drugs, used to treat various forms of allergic reactions.

Ruzam helps relieve swelling and allergic reactions

Main pharmacological properties of the solution:

1. Helps quickly relieve swelling of mucous tissues and skin.
2. Leads to a rapid decrease in the level of degranulated mast cells and eosinophils, which reduces inflammation.
3. Reduces the manifestation of allergic reactions.
4. Improves the functioning of the respiratory system and mucous tissues of the nasopharynx.
5. Helps increase the body's defenses.

Antiallergic drug administered subcutaneously. Within half an hour after the injection was given, you can notice a rapid decrease in the level of antibodies to the allergen, a decrease in the symptoms of cutaneous passive anaphylaxis.

Attention! The high effectiveness of the product has been proven in clinical settings. It was found that after 1-2 injections, the results of patients actively participating in the study demonstrated a rapid decrease in allergic inflammation, as well as a significant improvement in the patient’s condition.

Indications for use

Ruzam helps get rid of allergic reactions

Main indications for use of this product:

• chronic or seasonal runny nose of allergic origin;
• hives;
• angioedema;
• angioedema;
• bronchial asthma;
• dermatitis of allergic origin;
• photodermatosis;
• allergic conjunctivitis.

In addition, the use of a solution for subcutaneous injection is recommended if a person constantly experiences various infectious respiratory diseases. The drug is approved for use in children over 4 years of age.

Dosage and administration

Ruzam is available in the pharmacological form of a solution intended for injection under the skin. How to do them to get the most effective results?

The medicine should be injected into the upper shoulder, from the outside. The injection is not accompanied by pain or discomfort, so even small patients can easily tolerate it.

The dosage is selected by the doctor individually and depends on the age of the patient:

• children from 4 to 6 years old – 0.1 ml;
• children over 6 years old – 0.2 ml;
• adult patients – 0.2 ml.

Injections are given once a week. In this case, the duration of the course of treatment can last up to 9–10 weeks, that is, the entire course of therapy consists of 9–10 injections.

In the chronic form of an allergic disease, the patient may be prescribed 3-4 courses throughout the year with pauses of no more than 3 weeks. For severe, acute types of allergies, the dosage of the drug can be increased to 0.3 ml at a time, the frequency of injections is once every 5 days.

If a person is diagnosed with allergic pollinosis, it is recommended to start therapy with this drug approximately 7–8 weeks before the plant begins to flower, which causes the development of an allergic reaction. The attending physician will advise you on the specific timing of treatment.

Attention! The antiallergic solution Ruzam is highly effective in various forms and degrees of severity of allergic diseases, but this pharmacological agent is considered the most effective in the initial forms of pathological processes.

Contraindications

The drug is contraindicated during pregnancy

1. All trimesters of pregnancy.
2. Breastfeeding period.
3. Acute form of tuberculosis.
4. Infectious diseases in the period of exacerbation.
5. Individual sensitivity to components.

Pharmacological agent not used in the treatment of children under 4 years of age. Also, injections are strictly contraindicated during periods of exacerbation of various infectious diseases. The use of the drug is allowed only 4–5 weeks after illness.

In such cases, it is best to abandon the use of this solution and replace it with a drug with a similar mechanism of action.

It has not been established that Ruzam has any effect on the simultaneous use of other pharmacological drugs. His allowed to be combined with antibiotics, hormonal agents, as well as other antihistamines. Ruzam does not affect the absorption and effectiveness of other drugs.

It does not have a negative impact on a person’s ability to drive vehicles, complex production mechanisms, or engage in other activities that require increased concentration.

Attention! The solution must be used once - if there is medicine left in the ampoule after the injection, it should not be used.

Side effects and overdose

Ruzam solution for subcutaneous injections in most cases well tolerated by the body person. In medical practice, there is no information about cases of drug overdose.

In extremely rare cases, this medication can cause side effects in the form of a noticeable exacerbation of allergic diseases. Side effects noted when using Ruzam injections can be expressed in the form of coughing attacks, skin rashes, a jump in body temperature, chronic fatigue, weakness and apathy.

In most cases, side effects are reversible, that is, they disappear on their own after the end of the course of treatment. It is extremely rare that it may be necessary to discontinue Ruzam and replace it with a product with a similar principle of action.

Today, solution for subcutaneous injections Ruzam is considered a drug with original method of pharmacological action. This is because the main active component in the solution is an extract from a specific strain of Staphylococcus aureus. Due to the unique composition, there are no complete analogues of this medication.

Video: The best allergy drug

Ruzam is a modern, fast-acting allergy medicine. It is characterized by high efficiency, allows you to eliminate the manifestations of the disease and improve a person’s well-being. One injection every 7 days is enough to completely eliminate the manifestations of an allergic disease and significantly improve the patient’s well-being.

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To combat allergy symptoms, antihistamines are often used in tablets, spray, drops or gel form. Injections are used much less frequently. Injections are necessary for acute forms of allergies, as well as for prevention.

Ruzam is considered one of the effective medications on the market. Today it has no analogues. Using it, you can effectively stop the development of many types of allergic reactions.

Ruzam-M LLC produces Ruzam injections. The drug is both an antiallergic and an anti-inflammatory agent. Using it you can:

• Eliminate a number of allergy symptoms and alleviate the course of the disease.
• Block mast cell degranulation.
• Reduce the number of eosinophils in places where the inflammatory process occurs.
• Reduce swelling in the mucous membranes of the nose and respiratory organs.
• Reduce skin swelling.
• Reduce the amount of immunoglobulin E in the blood if its level is higher than normal.
• Increase the amount of secretory immunoglobulins A in the mucous membranes, because they protect the body from viruses and bacteria, and when they penetrate, they neutralize them.
• Reduce the accumulation of nitric oxide, which is an allergomarker, in the exhaled air stream.

Who is prescribed Ruzam for allergies?

Ruzam injections are prescribed to those who have:

• Hay fever and frequent respiratory infections.
• Allergic rhinitis (all-season) and bronchial asthma.
• Angioedema.
• Urticaria and allergic dermatitis (including chronic forms).

Instructions for use

Ruzam injections are administered under the skin to both children and adults. The dosage for children over 6 years old is 0.2 ml, and from 4 to 6 years old – 0.1 ml. The injection should be given no more than once every 7 days. The course of treatment is 5-10 weeks. During the year, the number of courses can reach up to 4. The minimum interval between courses must be at least 20 days.

With pollinosis, injections should be done 6-8 weeks before the flowering of plants that cause an allergic reaction. If respiratory infections are frequent, then Ruzam is used for prevention in spring and autumn.

It is permissible to increase the dose of the drug to 0.3 ml, if necessary. In this case, injections are administered every 5 days.

How long the treatment will take depends on the decision of the attending physician.

The drug may cause individual intolerance, and this occurs very rarely. It also practically does not cause any side effects.

Possible side effects from using the drug:

• If there is a chronic infectious disease, the symptoms intensify.
• With bronchitis, the cough becomes stronger.
• The temperature rises.

It is worth noting that even the presence of one or more side effects is not a cause for concern. They only indicate the start of the healing process. Therefore, you should not stop using the drug. Over time, the symptoms will completely disappear.

Ruza is contraindicated:

• Pregnant women, as well as while breastfeeding.
• Children under 4 years of age.
• For acute infectious diseases and tuberculosis.
• With decompensation of internal organs.

Price of medicine Ruzam for allergies

The drug is sold in pharmacies strictly according to a doctor's prescription. Its cost is quite high. This fact confuses many buyers, because the drug may not help.

A package with five ampoules of 0.2 ml each costs approximately 1,690 rubles. There are even ones at a price of 2270 rubles.

For treatment to be effective, the course must be completed over several weeks. This means that you need to expect to purchase 2-3 packages of the drug.

Active substance

Extract from the culture of thermophilic strain of Staphylococcus aureus (Staphylococcus aureus, strain C-2)

Release form, composition and packaging

Solution for subcutaneous administration

Excipients: (solution for injection 0.9%), phenol (0.025-0.05%).

0.2 ml - ampoules (5) - contour cell packaging (1) - cardboard packs.
0.2 ml - ampoules (5) - contour cell packaging (2) - cardboard packs.

Solution for subcutaneous administration in the form of a clear, colorless or slightly colored liquid with a slight phenol odor.

Excipients: sodium chloride (solution for injection 0.9%), phenol (0.025-0.05%).

0.5 ml - ampoules (5) - contour cell packaging (1) - cardboard packs.
0.5 ml - ampoules (5) - contour cell packaging (2) - cardboard packs.

pharmachologic effect

Has anti-inflammatory and anti-allergic effects. Reduces swelling of the mucous membranes and skin, reduces the content of eosinophils and degranulated mast cells at the site of inflammation and increases the concentration of secretory class A in the mucous membranes, thereby increasing their resistance to infection. Reduces the content of markers of allergic inflammation: total immunoglobulin class E in the blood and nitric oxide in the exhaled air.

Indications

Seasonal (hay fever) and year-round allergic rhinitis, urticaria and Quincke's edema, atopic and other allergic dermatitis, frequent respiratory infections.

Contraindications

Hypersensitivity to the drug, pregnancy and breastfeeding, children under 4 years of age, acute infection, in active form, decompensated diseases of internal organs.

Carefully. It should be used with caution in the presence of foci of chronic infection (chronic tonsillitis, sinusitis) due to the possibility of their exacerbation.

Dosage

Subcutaneously adults And children over 6 years 0.2 ml 1 time per week, children from 4 to 6 years old 0.1 ml 1 time per week; course 5-10 weeks. From 1 to 4 courses can be conducted during the year. For hay fever, the drug is administered 6-8 weeks before the flowering period of the allergenic plant; for frequent respiratory infections, prevention should be carried out in spring and autumn.

Side effects

Increase in body temperature to low-grade levels, weakness, exacerbation of a chronic source of infection, short-term worsening in chronic bronchitis, increased rash on the skin due to skin allergies. These symptoms, as a rule, are mild and transient and do not require discontinuation of the drug.

Drug interactions

Interactions of the drug RUZAM with other drugs have not been registered. RUZAM can be prescribed together with antihistamines, glucocorticosteroids or antibiotics.

For the treatment of various allergic ailments, not only local antiallergic, anti-inflammatory and decongestant drugs, as well as systemic drugs, are used, but also drugs with a direct antiallergic effect. Such drugs include Ruzam. In our article we will describe the instructions for use of the drug Ruzam, analogues of this drug, adverse reactions and contraindications.

Ruzam is a solution with antiallergic effect. This drug has a clear anti-allergic and anti-inflammatory effect. After its use, swelling of the skin and mucous membranes decreases, and the concentration of eosinophils in the blood and degranulated mast cells in the inflammatory focus also decreases. In addition, Ruzam injections help increase the amount of secretory immunoglobulin A, which is concentrated in the mucous membranes. Thanks to this medication, the human body’s resistance to all kinds of infections increases. After its use, the concentration of markers of the allergic inflammatory process decreases, that is, nitric oxide in the air exhaled by the patient, and total immunoglobulin E in the blood plasma.

Instructions for use and composition

The main active ingredient of the antiallergic drug is an extract of Staphylococcus aureus, namely its thermophilic strain. The drug Ruzam also contains the following auxiliary components:

• sodium chloride;
• phenol.

The drug is supplied in ampoules of 0.2 and 0.5 ml. They are placed in blister packs of five pieces. One cardboard box can contain 1 or 2 contour packages.

Indications for the use of this medicine are as follows:

• allergic year-round rhinitis and seasonal rhinitis (hay fever);
• angioedema;
• hives;
• bronchial asthma;
• skin diseases, namely atopic dermatitis and the presence of other allergic dermatitis;
• frequent incidence of respiratory infections.

No specific drug interactions with other medications have been identified. Ruza is allowed to be used in conjunction with antibiotics, glucocorticosteroid drugs and antihistamines.

Side effects

This allergy medicine has the following contraindications for its use:

1. Hypersensitivity to some ingredients of the drug;
2. The period of bearing a baby;
3. Breast-feeding;
4. The medicine is not prescribed to children under four years of age;
5. Acute infectious processes are a contraindication to the use of this drug;
6. Active form of tuberculosis;
7. Pathologies of internal organs (decompensated).

Attention! Ruzam is prescribed with extreme caution if there are chronic infectious foci in the patient’s body, for example, with chronic sinusitis or tonsillitis. This is due to the fact that while taking the medication, infectious processes may worsen.

When using any drug, side symptoms are observed. As for the drug Ruzam, the side effects from its use are as follows:

• during treatment, body temperature may increase (only to subfebrile levels);
• exacerbation of chronic infectious processes in the human body;
• general weakness;
• with chronic bronchitis, a rapid increase in cough may be observed;
• if there are skin allergic reactions, the rashes may worsen.

As a rule, the appearance of the above adverse reactions is mild and passes quickly, so you should not refuse to use the drug. If you purchased Ruzam, the instructions for use state that the drug does not have a negative effect on the speed of reactions, so you do not have to stop driving vehicles and performing potentially dangerous activities for the duration of treatment.

Dosage and administration

The drug is administered subcutaneously to children over six years of age and adults in a volume of 0.2 ml once a week. For the treatment of children from four years of age to 6 years of age, a volume of the drug equal to 0.1 ml is used, which is also administered subcutaneously once every seven days. The duration of therapy is from five to ten weeks. You can conduct from one to four such courses per year.

To treat hay fever, the drug is administered six or eight weeks before the start of the flowering period of grasses, trees and plants to which the patient is allergic. When preventing frequent respiratory infectious diseases, a course of treatment is carried out in the spring and autumn.

Analogues of the drug

Many patients are looking for analogues of Ruzam, but as pharmacists and doctors themselves say, this drug has a unique composition, so it has no analogues. If you cannot find Ruzam in the pharmacy, the only thing that can be advised in such a situation is to consult a doctor again to prescribe other antiallergic tablets or injections. Remember that only a doctor can select drug analogs or drug replacements.

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IDermatolog.ru

Ruzam

Active substance:

Pharmgroup:

Other immunomodulators

Instruction:

Clinical and pharmacological group

13.003 (Drug with antiallergic effect)

Release form, composition and packaging

0.2 ml - ampoules (5) - blister packs (1) - cardboard packs. 0.2 ml - ampoules (5) - blister packs (2) - cardboard packs.

Solution for subcutaneous administration in the form of a clear, colorless or slightly colored liquid with a slight phenol odor.

Excipients: sodium chloride (solution for injection 0.9%), phenol (0.025-0.05%).

0.5 ml - ampoules (5) - blister packs (1) - cardboard packs. 0.5 ml - ampoules (5) - blister packs (2) - cardboard packs.

pharmachologic effect

Has anti-inflammatory and anti-allergic effects. Reduces swelling of the mucous membranes and skin, reduces the content of eosinophils and degranulated mast cells at the site of inflammation and increases the concentration of secretory immunoglobulin class A in the mucous membranes, thereby increasing their resistance to infection. Reduces the content of markers of allergic inflammation: total immunoglobulin class E in the blood and nitric oxide in the exhaled air.

Dosage

Subcutaneously for adults and children over 6 years old, 0.2 ml once a week, for children from 4 to 6 years old, 0.1 ml once a week; course 5-10 weeks. From 1 to 4 courses can be conducted during the year. For hay fever, the drug is administered 6-8 weeks before the flowering period of the allergenic plant; for frequent respiratory infections, prevention should be carried out in spring and autumn.

Drug interactions

Interactions of the drug RUZAM® with other drugs have not been registered. RUZAM® can be prescribed together with antihistamines, glucocorticosteroids or antibiotics.

Side effects

Increase in body temperature to low-grade levels, weakness, exacerbation of a chronic source of infection, short-term increase in cough in chronic bronchitis, increase in skin rashes in skin allergies. These symptoms, as a rule, are mild and transient and do not require discontinuation of the drug.

Storage conditions and periods

Store the drug in a place protected from light and out of reach of children at a temperature of 4 to 20°C.

Shelf life: 4 years, do not use after the expiration date indicated on the package.

Indications

Seasonal (hay fever) and year-round allergic rhinitis, bronchial asthma, urticaria and angioedema, atopic and other allergic dermatitis, frequent respiratory infections.

Contraindications

Hypersensitivity to the drug, pregnancy and breastfeeding, children under 4 years of age, acute infection, active tuberculosis, decompensated diseases of internal organs.

Carefully. It should be used with caution in the presence of foci of chronic infection (chronic tonsillitis, sinusitis) due to the possibility of their exacerbation.

special instructions

The drug does not affect the performance of potentially hazardous activities that require special attention and quick reactions (driving a car, etc.).

Do not use the remaining solution in the ampoule.

Conditions for dispensing from pharmacies

The drug is available with a prescription.

Registration numbers

Solution for subcutaneous administration 0.2 ml: amp. 5 or 10 pcs LS-000791 (2025-11-10 – 2025-11-15)
solution for subcutaneous administration 0.5 ml: amp. 5 or 10 pcs LS-000791 (2025-11-10 – 2025-11-15)

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aznaetelivy.ru

Compound

Ruzam contains extract from a culture of a thermophilic strain of Staphylococcus aureus(Staphylococcus aureus, strain C-2). In addition, the composition includes phenol 0.025–0.05%, 0.9% sodium chloride solution.

Release form

Pharmacies sell a solution for subcutaneous injection. The cell packaging contains 5 ampoules. The packages are placed in a cardboard box.

pharmachologic effect

Antiallergic And immunomodulatory means.

Pharmacodynamics and pharmacokinetics

Ruzam represents anti-inflammatory And antiallergic medicine. It reduces edema mucous membranes and skin, increases the level secretory Ig class A in mucous membranes, helps reduce the amount degranulated mast cells And eosinophils at the site of inflammation, and also reduces the level markers of allergic inflammation. Expressiveness allergic reactions when taking this drug it decreases.

Indications for use

The medicine is used for:

Contraindications

Prohibited to do injections in case of a negative reaction to the components of the drug, lactation, pregnancy, acute infection, decompensated diseases internal organs and tuberculosis in an active form. In addition, contraindications include age under 4 years.

Side effects

Possible exacerbation reactions: malaise, weakness, low-grade fever body, worsening cough or rash. Usually these symptoms are mild, go away on their own and do not require discontinuation of use.

Instructions for use of Ruzam (Method and dosage)

Instructions for use Ruzama states that the drug is administered subcutaneously. From the age of 6 years, injections of 0.2 ml are given. For children 4-6 years old, dosages of 0.1 ml are recommended. The injection is given once every 7 days. Treatment can last from 5 to 10 weeks. There can be from 1 to 4 such courses per year. The interval between them should be at least 20 days.

When hay fever injections done 6-8 weeks before the plant that causes the allergy begins to bloom. For the purpose of prevention with frequent respiratory infections the drug is used in spring and autumn.

Instructions for use of Ruzam indicate that, if necessary, the dose can be increased to 0.3 ml, which is administered every 5 days.

Overdose

No information on overdose was provided.

Interaction

There is no significant interaction with other agents.

Terms of sale

The medicine is sold in the pharmacy network only with a doctor's prescription.

Storage conditions

The medicine should be kept out of the reach of small children and in a dark place. The storage temperature for ampoules with the drug is 4-20°C.

Best before date

Four years. Do not use ampoules with medicine after the expiration date indicated on the packaging.

Ruzam's analogs

Level 4 ATX code matches:

Currently, the drug is considered unique in its properties. Structural analogues of Ruzam with the same active ingredient are not available.

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Instructions for use

Ruzam is an antiallergic drug for the treatment of adults and children with an original mechanism of action. Produced in ampoules with a solution for subcutaneous injections.

The body has several different “links” of immunity: humoral, cellular, etc. When one of them is stimulated, the other is inhibited. Allergy is an excessive response of the humoral link. Ruzam stimulates the cellular link, automatically suppressing humoral and, as a consequence, the production of IgE and allergic reactions.

Indications

The drug is prescribed for the following diseases:

1. Year-round allergic rhinitis and seasonal (hay fever).
2. Bronchial asthma.
3. Hives.
4. Quincke's edema.
5. Allergic dermatitis (including atopic).
6. Frequent respiratory infections.

Dosage and administration

The drug is used for subcutaneous injections.

Adults and children over 6 years of age receive one injection per week. A single dosage of the drug is 0.2 ml.

Children aged 4-6 years are administered 0.1 ml once a week subcutaneously.

The duration of treatment is from 5 to 10 weeks. You can take up to 4 such courses per year.

In case of hay fever, the drug should be treated 6-8 weeks before the flowering of the plant that causes the allergy. In case of frequent acute respiratory infections, prevention should be carried out twice a year - in spring and autumn.

Contraindications

The drug should not be used to treat children under 4 years of age. Ruzam is also contraindicated in the following diseases:

• active tuberculosis;
• acute infections;
• decompensated diseases of internal organs;
• drug hypersensitivity.

The drug is prescribed with caution to patients with chronic tonsillitis, sinusitis and other foci of chronic infection, since there is a risk of their exacerbation.

Pregnancy and lactation

The drug is prohibited for use during pregnancy and lactation.

Overdose

There are currently no reports of overdose. If you encounter this phenomenon, be sure to tell your doctor about it.

Side effects

During treatment with Ruzam, side effects develop such as:

• low-grade fever;
• short-term increase in cough in chronic bronchitis;
• increased rashes on the skin due to dermatitis;
• lethargy, loss of strength;
• exacerbation of a chronic source of infection.

The occurrence of side effects indicates the positive dynamics of treatment. Symptoms are usually mild and do not require discontinuation of the drug or dose adjustment. After completing the course of therapy, the patients’ well-being is restored.

In isolated cases, side effects worsen. To reduce their intensity, you can take antibiotics, antihistamines, and glucocorticosteroids. You should consult a doctor to select medications.

Compound

Ruzam is a solution for subcutaneous injections. In appearance it is a clear liquid with a characteristic odor.

The drug contains the following components:

• extract from the culture of a thermophilic strain of Staphylococcus aureus, strain C-2. The drug does NOT contain a live culture of the microorganism;
• sodium chloride solution 0.9%;
• phenol 0.025 or 0.05%.

Pharmacology and pharmacokinetics

Ruzam has anti-inflammatory and antiallergic effects. The drug reduces swelling of the skin and mucous membranes, lowers the levels of eosinophils and mast cells at the site of inflammation. Activates the cellular component of immunity and reduces the reaction of passive cutaneous anaphylaxis and the level of antibodies in the blood.

It also increases the content of secretory immunoglobulin class A in the mucous membranes, thereby increasing their resistance to infections.

Analyzes of a patient undergoing treatment with Ruzam demonstrate a decrease in the levels of markers of allergic inflammation. The level of immunoglobulin E in the blood decreases, and there is less nitric oxide in the exhaled air.

Interaction with other drugs

Ruzam can be prescribed simultaneously with antibiotics, glucocorticosteroids and antihistamines.

No negative reactions due to any drug combinations were identified.

Best before date

Storage conditions

Store in a dark place at a temperature of +4 to +20 degrees.

Conditions for dispensing from pharmacies

On prescription.

Reviews

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* — Average value among several sellers at the time of monitoring, is not a public offer

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Compound

This unique product belongs to the modern class of drugs with active anti-inflammatory properties. Peptides are highly effective protein substances with high activity of biological components.

Ruzam contains a processed strain of a conditionally pathogenic microorganism - Staphylococcus aureus (there is no live culture in the medicine). Under the influence of high temperature, the peptide (adaptive protein) acquires pronounced anti-inflammatory and antiallergic properties. For this reason, successful therapy requires a minimum dosage of a modern drug.

The drug is sterile, side effects during therapy are rare. The unique drug not only suppresses acute reactions to irritants, but also strengthens the body's antiviral defense. The development of Russian scientists is certified, and the product is internationally recognized.

Release form

The manufacturer Ruzam-M LLC offers antiallergic medicine in the form of an injection solution. Dosage - 0.2 ml. The composition is intended for subcutaneous administration. There are 5 ampoules in a cardboard package. The medicine is suitable for adults and children, the difference in use is in the daily dosage.

The second option for eliminating negative signs of allergic diseases is Ruzam cream. In addition to a specially processed complex of bacteria, the product contains a bisphosphonate, olive oil, purified water, glycerin, two types of alcohol, and fragrance.

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Action

This unique drug has a positive effect on the body and reduces the signs of allergic reactions. The medicine exhibits not only antiallergic, but also active anti-inflammatory effects.

After the full course, a noticeable therapeutic effect appears. Many patients suffering from manifestations of bronchial asthma confirm that attacks occur much less frequently or stop altogether. A good result is noticeable in the treatment of allergic diseases accompanied by skin rashes.

Indications for use

An antiallergic drug is prescribed for the following diseases:

• allergic rhinitis (seasonal and year-round form);
• generalized and recurrent urticaria;
• bronchial asthma;
• hay fever;
• atopic dermatitis;
• allergic reactions that occur when stung by a bee or wasp;
• drug, latex and food allergies.

Contraindications

The biologically active agent should not be used for the following diseases and conditions:

• active form of tuberculosis;
• excessive sensitivity to the ingredients of the medicinal solution;
• patient age up to four years;
• breastfeeding period;
• decompensated pathologies of internal organs;
• pregnancy.

Time restrictions for injections of the drug Ruzam:

• asthmatic attacks, a decrease in peak expiratory flow below 80% of the optimal value;
• relapse of a chronic disease or development of acute respiratory viral infection;
• vaccination.

Instructions for use and dosage

• injections of a new generation antiallergic drug are prescribed by a doctor: The drug is not sold in pharmacies without a prescription;
• Children over 12 years of age and adult patients receive 1 injection per week, dosage - 0.2 ml. Duration of therapy - 5-10 weeks;
• for children aged 4 to 6 years, the course of therapy is shorter - from 6 to 8 injections, dosage - half the adult norm (0.1 ml);
• At least five days must pass between injections, the maximum interval to maintain the therapeutic effect is 20 days;
• if you are sensitive to the pollen of some plants, injections of the drug Ruzam are given 1-2 months before the start of the dangerous season with the obligatory continuation of the course during the flowering of allergenic plants;
• in severe cases of the disease, it is allowed to combine a unique remedy with traditional antihistamines and steroid compounds;
• if there is a high risk of colds, if the patient often suffers from acute respiratory viral infections, for prevention, doctors prescribe Ruza injections in the spring and autumn, during periods of greatest decline in immunity;
• the duration of treatment is determined by the doctor. Previous therapy does not affect the purpose and nature of use of the new allergy medicine;
• in the absence of seasonal exacerbations, you need to take 2 or more courses of Ruzam. Interval - 3 months. With this scheme of therapy, the greatest antiallergic effect is noticeable.

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Side effects

Negative reactions to a drug with a unique formula appear in isolated cases. Children and adults tolerate Ruzam injections well; after applying antiallergic cream, negative reactions also rarely occur.

Possible side effects:

• weakness;
• increase in subfertile temperature;
• increased cough;
• an increase in the volume of rashes.

Cost and analogues

Against the backdrop of the positive effects and high efficiency of the modern antiallergic composition, many patients are upset by the cost of the medicine. Ruzam is an expensive drug: a package of injection No. 5 costs 1260 rubles. For optimal results, a course of several weeks is needed. The patient should check with the doctor about the duration of treatment in order to calculate the cost of therapy (most often 2-3 packages are needed).

The antiallergic drug has a unique formula. Today there are no exact analogues to the development of Russian scientists.

Antiallergic cream Ruzam

Features of the remedy:

• The unique product contains the medicine Ruzam, olive oil, bisphosphonate, glycerin, flavoring, alcohol, purified water;
• a cream with a unique composition is suitable for treating epidermis prone to irritation;
• product for topical application for allergic reactions, inflammation, skin irritation;
• action: soothes irritated epidermis, moisturizes, nourishes, relieves redness, reduces the volume of rashes;
• a non-hormonal anti-inflammatory agent is applied two to three times a day to problem areas;
• the local remedy is effective for skin reactions that often accompany diseases of allergic origin;
• Ruzam cream is sold in pharmacies. You should not use the medicine without a prescription from an allergist;
• The protein drug is well tolerated by most patients; negative reactions are rare. In the absence of individual sensitivity, the cream is allowed to be used in children under one year of age (from 4 months).

allergiinet.com

Allergy medicine "Ruzam"

Manufacturer

• The drug Rusam is produced by the Russian company Ruzam-M LLC.

pharmachologic effect

• Ruzam is an antiallergic and anti-inflammatory drug.

After using it:

• reduction in the number of eosinophils in the focus of the inflammatory process;
• blocking mast cell degranulation;
• elimination of some allergy symptoms, alleviation of the disease in general;
• decrease in swelling of the mucous membranes in the nasal cavity and organs of the respiratory system;
• reduction of skin swelling;
• a decrease in the blood level of class E immunoglobulins, which, when exceeding the permissible norm, provoke an allergic reaction;
• a decrease in the concentration of nitric oxide (one of the markers of allergies) in exhaled air;
• an increase in the level of secretory immunoglobulin class A in the mucous membranes, which performs protective functions and prevents the penetration of microorganisms into the body, deactivates viruses and bacteria.

Release form and composition of the drug "Ruzam"

• Ruzam is sold in pharmacies in the form of a colorless (or slightly tinted) transparent solution for subcutaneous administration with a faint odor of phenol. Ampoules are packed in a cardboard box - five pieces each. You can purchase ampoules with a volume of 0.2 or 0.5 milliliters.
• The main active component of Ruzam (regardless of the volume of the ampoule) is an extract isolated from a thermophilic strain of Staphylococcus aureus (strain C-2 Staphylococcus aureus). This substance is successfully used in the treatment of not only allergic diseases, but also some infectious diseases (bronchitis, acute respiratory infections).
• The auxiliary components are an injection solution of sodium chloride 0.9% and phenol (0.025-0.05%).

Sales in pharmacies

• It is possible to purchase Ruzam in pharmacy chains only with a doctor’s prescription.

Shelf life

• 4 years (do not use after expiration date)

Prescription of antiallergen "Ruzam"

Ruzam is prescribed for the treatment of:

• hay fever;
• allergic rhinitis (all-season);
• Quincke's edema;
• bronchial asthma;
• systematic respiratory infections;
• hives;
• allergic dermatitis, including chronic (atopic dermatitis).

Dosing of the drug Ruzam

To prevent respiratory diseases, treatment with Ruzam is carried out in spring and autumn.

If you suffer from hay fever (seasonal allergic rhinitis provoked by pollen), then injections should be given one and a half to two months before the allergen plant begins to bloom.

At the discretion of the doctor, the dosage and frequency of injections may be increased. Some patients are prescribed Ruzam 0.3 ml every five days.

Contraindications for Ruzam

The drug is not prescribed (temporary contraindications):

• children under four years old;
• pregnant and lactating women;
• patients with tuberculosis (during its course in the active stage);
• with infectious diseases that occur in severe form, with complications.

Absolute contraindications for treatment with Ruzam

• with individual intolerance to the components of Ruzam;
• diseases and pathologies of internal organs in the stage of decompensation.
• in case of chronic infections (sinusitis, tonsillitis, etc.)

What side effects to expect from anti-allergen "Ruzam"

According to the manufacturer, the use of Ruzam injection solution in some cases may be accompanied by the following side effects:

• lethargy, general weakness;
• short-term increase in cough (with chronic bronchitis) or rashes on the skin (with allergic skin lesions);
• increase in body temperature up to 37-38 (subfebrile fever).

Such reactions are observed rarely, are short-term in nature and do not differ in particular intensity. They usually go away on their own; you don’t need to stop Ruzam injections for this.

What is known about overdose

There have been no cases of overdose with Ruzam. It is only important to follow the doctor’s instructions and not exceed the prescribed doses and frequency of injections.

additional information

No interaction of Ruzam with other drugs has been established. Injections with Ruzam can be done during treatment with antibiotics, glucocorticosteroids or other antiallergic drugs.

Ruzam does not affect the body’s coordination abilities, so it can be used by people whose professions involve risk and require increased attention and quick reaction.

It is not recommended to use the remaining solution in the ampoule in the future. Once the bottle has been opened and the required dose has been dispensed, it should be thrown away along with the unused liquid.

How and how long can Ruzam be stored?

Ruzam has a long shelf life - 4 years. Expired product should not be used for injections.

The drug should be stored at a temperature of 4 to 20 degrees, in a dark place inaccessible to children.

Price for the drug

Antiallergic solution Ruzam is not a cheap medicine. This is noted by many patients to whom it was prescribed. The cost of a package of five 0.2 ml ampoules is 1600-2100 rubles.

What can replace the medicine?

Ruzam is a drug unique in its composition and mechanism of action, which has no structural analogues.

Consumer rating

In general, you can find a lot of positive reviews about Ruzam in terms of its effectiveness. For many, the injections helped relieve the symptoms of hay fever, allergic rhinitis and urticaria, reduce the frequency of attacks and alleviate the general condition of bronchial asthma. But there were also those whom Ruzam did not help. The reason for this, as the patients themselves later admitted, lay in an incorrectly diagnosed allergen and the use of the drug without a doctor’s prescription.

Among the shortcomings, they note the inaccessibility of Ruzam both in terms of price (according to many, the medicine is a bit expensive) and in terms of its availability in pharmacies (in many cities it is possible to buy it only through online pharmacies).

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Composition and release form of the product

When creating this drug, pharmacists use an extract from a culture of the isolated thermophilic strain C-2 of Staphylococcus aureus. Phenol and sodium chloride are used as additional components. A colorless or slightly colored solution for subcutaneous injection with a characteristic odor is packaged in ampoules with a dosage of 0.2 and 0.5 ml.

In a cardboard pack of the drug, in contour packages, there are 5 or 10 ampoules, depending on the type of packaging. In the pharmacy chain, the medicine “Ruzam” (the instructions warn about this) is dispensed only with a prescription from the treating doctor.

How the drug works: pharmacological properties

The mechanism of action of the drug “Ruzam” is quite original, as it affects several parts of the immune system. In the human body, such a chain is quite large. But the humoral “link” is responsible for the manifestation of allergies, which, under the influence of an allergen, exhibits an excessive reaction.

As described by the available drug « Ruzam" instructions for use, its active substance activates the cellular mechanism of immunity, thereby suppressing the humoral link. As a result of this effect, the level of eosinophils in the patient’s blood decreases, and the number of mast cells in the site of inflammation decreases. Already 20-30 minutes after the injection, the level of antibodies to the allergen sharply decreases, and the manifestation of cutaneous passive anaphylaxis also significantly decreases.

Advantageous features of the medicine

In addition to the pronounced antiallergic effect of Ruzam, the instructions describe its anti-inflammatory properties. They are achieved by increasing the content of secretory immunoglobulin A class in the mucous membranes. As a result, their resistance to various infections increases significantly.

After just one injection, the test results of patients clearly demonstrate an active decrease in the indicators of the allergic inflammatory process. Doctors also note a reduction in the level of immunoglobulin E class and the amount of nitric oxide in exhaled air.

Who is the drug indicated for?

Thanks to the complex original mechanism of action, the instructions recommend using “Ruzam” (an allergy medicine) for the following diseases:

• angioedema;
• bronchial asthma;
• allergic rhinitis;
• seasonal hay fever;
• dermatitis of allergic origin.

The medication is used to prevent frequent respiratory ailments in pediatrics. It is prescribed to children from 4 years of age who suffer from seasonal acute respiratory viral infections and acute respiratory infections.

Medicine dosing system

This medication is used exclusively for subcutaneous injections. The recommended single dose for adult patients and children over 6 years of age is 0.2 ml. The interval between injections is 7 days. The duration of therapy is prescribed individually and varies from 5 to 10 weeks.

As for the youngest group of patients, from 4 to 6 years old, who are prescribed the drug "Ruzam", the instructions for use for children limit them to a single dosage of 0.1 ml. The treatment regimen for small patients is identical to the recommendations for adult patients - the injection should be given once a week.

The decision on the need for repeated courses of treatment rests with the attending physician. If necessary, the patient can undergo 4 courses of therapy per calendar year. With severe seasonal hay fever, patients are recommended to undergo treatment 6-8 weeks before the onset of the allergen. For children who often suffer from seasonal respiratory infections, pediatricians prescribe 2 courses per year. It is advisable to carry them out in autumn and spring.

Contraindications: who should not use the product?

It is strictly prohibited to use the medicine to treat allergies in children under four years of age. The instructions for use do not recommend using the product “Ruzam” (0.2 ml) for patients suffering from the following ailments:

• active form of tuberculosis;
• decompensated diseases of internal organs;
• acute infections.

Hypersensitivity to the active substance or auxiliary components of the drug is also a serious reason to refuse its use.

The instructions recommend prescribing Ruzam to patients with chronic infections, including sinusitis and tonsillitis, with caution, since in these cases the risk of exacerbations increases significantly.

Use of drugs during pregnancy and lactation

For expectant mothers, using the medicine throughout pregnancy is strictly prohibited, since the effect of an extract from a strain of Staphylococcus aureus on the fetus has not been studied.

The drug is also not prescribed during lactation, because the active substance enters the newborn’s body with mother’s milk and can cause a number of dangerous reactions. In situations where it is not possible to replace the medicine with another, women are advised to stop breastfeeding and only then begin therapy.

Side effects of the medication

When prescribing treatment with Ruzam, the doctor must inform the patient about the following possible reactions of the body:

• an increase in body temperature within the subfebrile range;
• loss of strength and lethargy;
• drowsiness;
• increased cough (short-term) in patients with chronic bronchitis;
• and for skin dermatitis, a slight increase in rashes.

Unlike other drugs, the instructions for use of Ruzam do not recommend stopping it if such reactions occur. Such manifestations, on the contrary, indicate positive dynamics. Typically, side effects are mild and do not require adjustment of the dosage system.

In isolated cases, when the symptoms described above are clearly manifested, it is necessary to consult a doctor who can select effective medications. These can be antibacterial or antihistamine drugs, the action of which neutralizes the side symptoms of the drug "Ruzam".

After completing the course of therapy, the patients’ well-being improves significantly, and side symptoms disappear.

Overdose and interaction with other drugs

During the entire period of use of the drug, no cases of overdose were recorded. All complaints about various reactions of the body were only a consequence of the side effects of the active substance.

But if, by chance, a large dose of medication was injected subcutaneously, you must immediately contact a medical facility. Doctors will select appropriate symptomatic therapy.

Based on the results of numerous studies, it has been established that the use of the drug can be combined with antibacterial therapy, as well as with the use of glucocorticosteroids and antihistamines.

The occurrence of any adverse reactions with various combinations was not established. Therefore, when prescribing the drug “Ruzam”, it is recommended to take into account only the patient’s age and the presence of diseases for which it is contraindicated.

Structural analogues of the product

The composition of the drug “Ruzam” is unique, since it is based on an extract of one of the strains of Staphylococcus aureus. Therefore, the drug has no structural analogues in the form of a solution.

The only medicine based on an identical active ingredient is Ruzam cream. The instructions for use recommend using it as a prophylactic for skin care for people prone to allergies. The cream softens the skin and strengthens the cellular immune system, which increases the resistance of the epidermis to various infections and allergic reactions.

Cream "Ruzam": application features

The drug is applied to the skin in a thin layer once a day for prophylactic purposes. If the first signs of infection or a characteristic allergic rash have already appeared on the skin, it is recommended to double the daily dose. That is, the cream must be applied to the affected areas in the morning and before bed. The duration of treatment is completely individual, and should only be determined by an experienced doctor.

Like the solution, the cream has a number of contraindications that need to be taken into account before starting treatment. These include:

• acute infectious processes of various etiologies;
• active form of tuberculosis;
• individual hypersensitivity to the components of the product;
• pregnancy and lactation;
• age up to 4 years;
• decompensated diseases of internal organs.

How to replace the product: analogues

If you need to replace the Ruzam product, the instructions for use do not describe analogues. And this is quite logical, because, as already mentioned, the medicine has no structural analogues. Therefore, if for some reason the patient cannot purchase the product or does not want to use it, fearing the consequences of side effects, it is recommended to consult a doctor.

The specialist will select an effective medicine or a set of medicines that will help cope with allergies. Self-medication in such a situation is strictly prohibited, because the body’s reaction can be unpredictable. ">