Prescription of medicine asparkam. Asparkam - official instructions for use (in tablet form), indications and contraindications, analogue drugs

What is Asparkam used for? Its use in medicine is quite widespread. It is effective for restoring electrolyte balance, heart rate, and regulating metabolism in the human body. It also helps with urolithiasis, promoting the removal of stones based on calcium compounds.

Composition and release form

Asparkam is a medication that affects metabolic processes in the body.. Its mechanism of action lies in the ability of aspartates to introduce potassium and magnesium ions inside cells, which contributes to their direct participation in metabolism. This leads to the restoration of electrolyte balance, replenishing the lack of potassium and magnesium.

The drug contains 2 active ingredients:

In addition to the main components, there are excipients that differ depending on the form of release. The method of administration of the drug also depends on the form. Asparkam is produced:

1. In the form of tablets. The medication Asparkam, which is available in tablet form, is taken orally. They are drunk half an hour after eating (this is how maximum benefits are achieved). They are white in color and have an oblong, convex shape. One tablet contains 175 mg of potassium and the same amount of magnesium, as well as additional substances: starch, talc, calcium stearate, copovidone. They go on sale in 10 and 50 pieces in blisters, which are packed in cardboard boxes.
2. In the form of a solution for injection. It is contained in glass ampoules of 5, 10 and 20 ml. Ampoules are packed in boxes of 5 and 10 pieces. A 10 ml ampoule contains 0.45 g of potassium and 0.4 g of magnesium. It is administered intravenously by jet method very slowly (about 5 ml in 60 seconds), dissolving the drug in sodium chloride or glucose solution.
3. In the form of a solution for droppers. Available in 400 ml glass bottles. In addition to potassium (about 11 g) and magnesium (about 8 g), it contains 20 g of sorbitol. The rate of administration should not exceed 25 drops in 60 seconds.

The dosage of the drug and the duration of treatment depend on the severity of symptoms, the age of the patient, and possible contraindications. Their appointment and control is carried out by the attending physician.

In general, the Asparkam tablet regimen should be taken as follows:

The drug is quickly absorbed, the maximum concentration of the active ingredients is observed within 2 hours after taking it. It is excreted mainly due to the functioning of the kidneys and partly the intestines.

When should you take the drug?

When prescribing Asparkam, patients do not always know what it is used for. Its action is aimed at restoring the lack of potassium and magnesium, which can be caused by many phenomena.

So, for the drug Asparkam, the indications for use are as follows:

Important! Also, simultaneous use of the drug Diacarb with Asparkam effectively eliminates high intracranial pressure. This can save the patient from a stroke.

Asparkam has a number of features that should be taken into account when using:

Important! Improper use of the drug can lead to many unpleasant phenomena, as well as the death of the patient.

Overdose, contraindications and side effects

When using the drug in the form of injections or infusions (intravenous drips), an overdose sometimes occurs. Its characteristic symptoms:

• a sharp decrease in blood pressure;
• severe redness and swelling of the skin on the face;
• strong thirst;
• rapid breathing (sometimes with wheezing);
• convulsions;
• sometimes the patient may fall into a coma.

When such symptoms appear, first of all, you need to stop taking Asparkam. Next, you should intravenously inject a solution of calcium gluconate, which is capable of removing excess potassium from the body. In the most severe cases, blood purification is prescribed.

Like any medicine, it has limitations that must be considered before prescribing treatment. The contraindications for Asparkam are as follows:

Treatment with Asparkam is not recommended for pregnant women (especially during the first trimester), nursing mothers (can pass into breast milk), and small children. However, in practice, it is sometimes still prescribed to children (for example, for an epileptic seizure). In this case, the doctor must take into account the possible harm that is caused to the child’s body.

You should not drink alcohol while taking the drug, as it can negatively affect the kidneys' ability to eliminate the drug.

Taking Asparkam (especially long-term) may cause some side effects. Among them are the following negative phenomena:

Sometimes patients fall into a long-term coma. This condition greatly complicates the treatment process. Lethal (fatal) outcome is also possible.

To avoid this, it is worth remembering that if any side effects are detected, it is necessary to reduce the dosage of the drug or stop taking it altogether.

Asparkam is a medication that helps restore metabolic processes in the body due to a lack of potassium and magnesium. It is effective for restoring electrolyte balance, regulating metabolic processes, and combating heart rhythm disturbances.

Asparkam is a complex drug, a source of magnesium and potassium ions, which regulate metabolic processes in the body. The active ingredient is potassium and magnesium aspartate.

A source of potassium (K+) and magnesium (Mg2+) ions, regulates metabolic processes, helps restore electrolyte balance, and has an antiarrhythmic effect.

Potassium- participates both in the conduction of impulses along nerve fibers and in synaptic transmission, the implementation of muscle contractions, and the maintenance of normal cardiac activity.

Impaired potassium metabolism leads to changes in the excitability of muscles and nerves. Active ion transport maintains a high K+ gradient across the plasma membrane.

In small doses, potassium ions dilate the coronary arteries, in large doses they narrow them. It has a negative chrono- and bathmotropic effect, in high doses - a negative ino- and dromotropic effect, as well as a moderate diuretic effect.

Magnesium- is a cofactor for 300 enzyme reactions. An irreplaceable element in processes that ensure the supply and consumption of energy. Participates in the balance of electrolytes, ion transport, membrane permeability, neuromuscular excitability.

It is part of the structure of (pentose phosphate) DNA, participates in RNA synthesis, the apparatus of heredity, cell growth, and in the process of cell division. Limits and prevents excessive release of catecholamine under stress, lipolysis and release of free fatty acids are possible.

It is a “physiological” BMCC. Promotes the penetration of potassium ions into cells.

Asparaginate promotes the penetration of K+ and Mg2+ into the intracellular space, stimulates the intercellular synthesis of phosphates.

Asparkam is produced in the form of tablets, solution for injections and for infusion.

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Price in pharmacies

Information about the price of Asparkam in Russian pharmacies is taken from online pharmacies and may differ slightly from the price in your region.

In Moscow pharmacies, the price of Asparkam tablets for 20 pieces is from 31 to 37 rubles, tablets for 50 pieces are from 45 to 58 rubles.

Conditions for dispensing from pharmacies - tablets are sold without a prescription.

Store in a dry place, at a temperature of 15–25 °C. Shelf life – 3 years.

A list of analogues is presented below.

What does Asparkam help with?

The drug Asparkam is prescribed in combination with drugs that stimulate the heart in the presence of heart failure, disturbances in heart rhythm, and conditions after myocardial infarction.

Additionally used to maximize the effectiveness of cardiac glycosides and improve their tolerability. The drug will also be effective in cases of deficiency of potassium and magnesium ions.

The drug is also used in case of intolerance or toxic effects of digitalis preparations on the body.

Diacarb and Asparkam in combination are used for increased intracranial pressure (including in children over four months of age), for edema syndrome, epilepsy, glaucoma, gout, Meniere's disease, as well as for potassium and magnesium deficiency.

Instructions for use of Asparkam, doses and rules

The tablets are taken orally, after meals, with clean water.

The standard dosage of Asparkam, according to the instructions for use, is 2 tablets \ 3 times a day (morning\lunch\evening). The minimum course of treatment is up to 4 weeks. Further use of the drug is possible as prescribed by a doctor.

For prophylaxis, Asparkam is taken 1 tablet \ 3 times a day for a monthly course.

Asparkam injections (ampoules)

The solution is administered intravenously by drip or intravenous stream slowly.

For intravenous infusion, 20 ml is diluted in 100-200 ml of sodium chloride 0.9% or glucose solution 0.5%. The dose for adults is 10-20 ml \ 1-2 times a day, the rate of administration is 25 drops per minute.

For intravenous injection, a 10 ml ampoule is diluted in 20 ml of 0.9% sodium chloride solution. Inject Asparkam into a vein no faster than 5 ml per minute.

Important information

With rapid intravenous administration of Asparkam, all symptoms of hyperkalemia (nausea, vomiting, diarrhea, paresthesia) and hypermagnesemia (hyperemia of the facial skin, thirst, bradycardia, decreased blood pressure, muscle weakness, fatigue, paresis, coma, areflexia, respiratory depression, convulsions) may appear. .

In patients receiving the drug for a long time, it is necessary to monitor ECG data, as well as serum concentrations of K and Mg.

With rapid injection into a vein, skin hyperemia may develop.

Use during pregnancy and lactation

The use of the drug during pregnancy is possible only if the expected benefit to the woman outweighs the potential risk to the fetus.

If the drug is used during breastfeeding, it is recommended to stop breastfeeding.

Features of application

Before using the drug, read the sections of the instructions for use about contraindications, possible side effects and other important information.

Side effects of Asparkam

The instructions for use warn of the possibility of developing side effects of the drug Asparkam:

• Possible nausea, discomfort or burning in the epigastric region (with cholecystitis and anacid gastritis).

These phenomena usually disappear with a reduction in the dose of the drug.

Contraindications

The use of Asparkam is contraindicated for the following diseases or conditions:

• hypersensitivity to the components of the drug;
• acute and chronic renal failure;
• oliguria, anuria; Addison's disease;
• hyperkalemia, hypermagnesemia; AV blockade II–III degree;
• cardiogenic shock (with systolic blood pressure<90 мм рт. ст.);
• children and adolescents under 18 years of age (there is insufficient clinical data on the use of the drug in this age group of patients).

Overdose

At the moment, no cases of overdose have been registered.

Theoretically, in case of overdose, symptoms of hyperkalemia (nausea, vomiting, diarrhea, abdominal pain, metallic taste in the mouth, bradycardia, weakness, disorientation, muscle paralysis, paresthesia of the extremities) and hypermagnesemia (redness of the facial skin, thirst, arterial hypotension, hyporeflexia, impaired neuromuscular transmission, respiratory depression, arrhythmia, convulsions).

The ECG records an increase in the amplitude of the T wave, a decrease in the amplitude of the P wave, and an expansion of the QRS complex.

It is necessary to discontinue the drug, symptomatic therapy (iv administration of calcium chloride solution at a dose of 100 mg per minute), and if necessary, hemodialysis.

List of analogues of Asparkam

If it is necessary to replace the drug, there are two options - choosing another medication with the same active substance or a drug with a similar effect, but a different active substance. Drugs with similar effects are united by the same ATC code.

Analogues of Asparkam, list of drugs:

1. Aspangin,
2. Potassium and magnesium aspartate,

Matches by ATX code:

• Asparkam-Farmak,
• Potassium and magnesium aspartate,
• Pamaton,
• Panangin.

When choosing a replacement, it is important to understand that the price, instructions for use and reviews of Aspark do not apply to analogues. Before replacing, you must obtain the approval of your doctor and do not replace the drug yourself.

Special information for healthcare workers

Interactions

The simultaneous use of Asparkam with potassium-sparing diuretics or ACE inhibitors increases the possibility of developing hyperkalemia.

The drug helps reduce sensitivity to cardiac glycosides.

special instructions

Do not use for rhythm disturbances in combination with AV blockade.

For one bottle: potassium aspartate - 4.64 g, magnesium aspartate - 3.16 g, sorbitol - 8.00 g, water for injection - up to 400 ml.

Pharmacotherapeutic group

Plasma replacement and perfusion solutions. Solutions for intravenous administration. Solutions affecting electrolyte balance. ATS code: В05ВВ01.

pharmachologic effect

The drug helps eliminate potassium and magnesium deficiency, has an antiarrhythmic effect, improves metabolism in the myocardium, and normalizes electrolyte balance. It is a donor of potassium and magnesium ions and promotes their penetration into the intracellular space. Entering cells, aspartate is included in metabolic processes. Mg 2+ ions reduce the excitability of neurons, slow down neuromuscular transmission, participate in many enzymatic reactions, activate Na + -K + -ATPase, removing Na + from the cell and returning K +, reduce the concentration of Na +, and prevent the exchange of Na + on Ca 2+ in vascular smooth muscles, reducing their resistance. K+ ions stimulate the synthesis of ATP, glucogen, proteins, acetylcholine, etc., reduce the excitability and conductivity of the myocardium, and in high concentrations inhibit automaticity. Both ions are involved in maintaining intracellular osmotic pressure, the processes of conduction and transmission of nerve impulses, and the contraction of skeletal muscles.

Indications for use

To eliminate potassium and magnesium deficiency as part of combination therapy for chronic heart failure, in the post-infarction period, heart rhythm disturbances (tachyarrhythmias, extrasystoles, including arrhythmias due to intoxication with cardiac glycosides).

Directions for use and doses

The drug is administered intravenously, 300-400 ml of solution 1-2 times a day at a rate of 20-25 drops per minute. The dose and duration of administration of the drug is determined individually.

Side effect

When the recommended drip rate was followed, side effects were rarely observed.
With rapid intravenous administration, symptoms of hyperkalemia and hypermagnesemia may occur: nausea, vomiting, muscle weakness.
From the central nervous system: paresthesia, paresis, hyporeflexia, coma.
From the cardiovascular system: bradycardia, arrhythmia, marked decrease in blood pressure, paradoxical increase in the number of extrasystoles, atrioventricular block.
If the above adverse reactions or adverse reactions not listed in these instructions for medical use of the drug occur, you should consult a doctor.

Contraindications

Acute renal failure;
- chronic renal failure;
- hyperkalemia;
- hypermagnesemia;
- atrioventricular block;
- myasthenia gravis;
- insufficiency of adrenal cortex function, including Addison's disease;
- cardiogenic shock (BP<90 мм рт. ст.).
- hypersensitivity to the components of the drug;
- hemolysis;
- oliguria, anuria;
- arterial hypotension;
- acute metabolic acidosis;
- dehydration;
- age under 18 years (efficacy and safety in children under 18 years of age have not been studied).
Carefully:
- severe liver dysfunction;
- metabolic acidosis;
- heart failure with peripheral edema;
- pulmonary edema;
- risk of edema;
- impaired excretory function of the kidneys;
- decreased kidney function if it is impossible to regularly monitor the magnesium content in the blood serum (the danger of accumulation and increase in magnesium content to a toxic level);
- hypophosphatemia;
- pregnancy and breastfeeding period.

Overdose

Overdose is accompanied by symptoms of hyperkalemia and hypermagnesemia.
Symptoms of hyperkalemia: increased fatigue, muscle weakness, paresthesia, disturbances of consciousness, cardiac dysfunction (bradycardia, atrioventricular block, arrhythmias, cardiac arrest).
Symptoms of hypermagnesemia: decreased neuromuscular excitability, nausea, vomiting, lethargy, decreased blood pressure, especially with high levels of magnesium in the blood, disappearance of deep reflexes, respiratory paralysis, coma.
For symptomatic treatment of overdose, it is recommended to stop the infusion of Asparkam-L and prescribe intravenous calcium chloride 100 mg/min, with dialysis if necessary. Therapy involves intravenous administration of solutions of calcium and sodium salts, intravenous drip administration of glucose with insulin (1 unit of insulin for every 3-5 g of glucose). For peripheral paresis caused by the toxic effect of Mg ions, especially with paralysis of the respiratory muscles, physostigmine can be administered. In the presence of renal failure, extrarenal elimination can be achieved by hemodialysis or peritoneal dialysis.

Precautionary measures

Only use clear solutions in undamaged bottles. After opening the bottle, the drug must be used immediately. Intravenous administration should be done slowly. If turbidity or opalescence occurs when mixing the drug with other injection solutions, then such mixtures should not be administered. In elderly patients with chronic heart failure, large volumes of fluid should be avoided. It is necessary to monitor the pressure in the jugular veins and the condition of the lower parts of the lungs for crepitus. In elderly and somatically ill patients, it is recommended to monitor diuresis and central venous pressure.
The use of the drug is not recommended in the presence of AV blockade. Particular attention should be paid to patients who suffer from diseases in which hyperkalemia may develop; For this category of patients, it is recommended to regularly monitor the level of electrolytes in the blood.

Use during pregnancy and lactation

There have been no studies on the safety of using the drug Asparkam-L during pregnancy, therefore the use of the drug is possible only for health reasons.
Since it is unknown whether potassium and magnesium aspartate passes into breast milk, caution should be exercised when using the drug during breastfeeding.

One of the most effective over-the-counter drugs that correct arrhythmia is Asparkam. The essence of its action is the normalization of metabolism and electrolytes. It is a metabolite, a source of potassium and magnesium. Due to this, it normalizes the heart rhythm. The medicine belongs to the most affordable price segment, but this does not prevent it from being more effective than many expensive analogues. Asparkam is loved by athletes for its ability to lose extra pounds while drinking more.

Compound

Asparkam is available in the form of tablets and solution for injection. The package contains 50 tablets or 10 ampoules of 5, 10 ml.

• Each tablet contains 0.2 g of potassium and magnesium, as well as excipients for the cachet.
• Asparkam solution contains anhydrous magnesium aspartate – 40 mg and potassium – 45 mg. This is equivalent to 3 mg of pure magnesium and 10 mg of pure potassium. In addition, the injection form contains sorbitol and water.

Potassium ensures the passage of nerve impulses, exhibits diuretic properties and plays a major role in muscle contraction. Magnesium is responsible for enzyme activity, participates in ion transport and cell growth.

The mechanism of action is to correct metabolic processes with potassium and magnesium. These elements easily overcome the cell membrane and replenish the deficiency of microelements lost due to time or pathological changes. A normalized electrolyte balance leads to a decrease in myocardial conductivity, dampens its excitability and allows the electrical impulses of the cardiac conduction system to work in the usual manner.

At the same time, metabolic processes improve, the susceptibility of the myocardium to cardiac glycosides becomes better, since their toxicity drops sharply. The coronary vessels also respond to these changes, since the normal rhythmic contractility of the heart allows them to provide optimal blood supply to organs and tissues with nutrients and oxygen.

Magnesium ions activate ATP, which balances the flow of sodium into the intercellular space and potassium into the intracellular space. A decrease in Na+ concentration inside the cell blocks the exchange of calcium and sodium in the smooth muscles of blood vessels, which automatically relaxes them. An increase in K+ stimulates the production of ATP - a source of energy, glycogen, proteins and acetylcholine, which prevents cardiac ischemia and cellular hypoxia.

Asparkam enters the bloodstream through the digestive tract, and from there in the form of asparginate into the myocardium, where it begins to work.

Properties

They are caused by the combined effect of potassium and magnesium on the heart muscle and help restore it after a heart attack. K+ improves the contractility of the heart, reducing excitability and improving muscle conduction. It expands the lumen of the great vessels of the heart. Magnesium stimulates the synthesis of muscle tissue necessary to compensate for the defect and stimulates cell division, promoting rapid regeneration.




These properties are used in the treatment of glaucoma and high intracranial pressure. Normalization of metabolism and electrolyte balance relieves almost all negative symptoms associated with vascular overload. The side effect is accelerated, which turned out to be important for athletes. Therefore, Asparkam is quite popular in strength sports.

Potassium and magnesium

Cardiologists constantly talk about the importance of these microelements. There is nothing surprising about this. The rhythm of heart contractions is determined by the quality of the conduction system of the myocardium, in which impulses are generated independently and, passing through bundles of special nerve fibers, activate the periodicity of contraction of the atria and ventricles in a certain sequence. The normal conductivity of these fibers depends on the concentration of magnesium and potassium in them.




The heartbeat is normal, which means the person feels good, since each organ receives appropriate nutrition and oxygen on time and with a clear sequence. With a lack of magnesium, problems begin in the coronary vessels. They soften and become wide. As a result, the blood slows down, the organs begin to experience discomfort, and the patient begins to feel worse.

The opposite effect is observed with excess potassium: the coronaries become fragile and narrow. But this also brings nothing but trouble to the bloodstream, since blood cannot enter the main lines in normal quantities and be pumped to the organs. The loss of magnesium by cells, its release into the intercellular space entails the destruction of complex carbohydrates, and hyperkalemia occurs.




Magnesium takes part in all metabolic processes without exception. It is a catalyst for cell division, RNA synthesis, and provides the laying of hereditary information. But if its concentration decreases, the cell membrane becomes an insurmountable obstacle for the trace element. Magnesium Asparkam helps get into it with an additional amount of the element.

There are pitfalls here. An overdose of the drug is fraught with hypermagnesemia, and this is the cause of cardiac arrest. Therefore, self-prescription of a “harmless” drug is unacceptable.

The concentration of potassium and magnesium in the cell is especially important during pregnancy. They ensure stable development and growth of the fetus. But Asparkam is prescribed to pregnant women with great caution, preferring German Panangin, a vitamin for the heart. Symptoms of overdose are fatigue and dysuria.

Another nuance: a lack of potassium changes nervous excitability, and a deficiency of intracellular magnesium causes an imbalance in the generation and expenditure of energy, which stimulates convulsions, numbness of the limbs, and lethargy.

Indications for taking Asparkam

The main function of Asparkam is the transport of microelements into the cell. The drug is prescribed in the following cases:

• Deficiency of K+ and Mg+ in the body.
• Heart rhythm disturbance.
• IHD, post-infarction condition.
• Ventricular extrasystole.
• Foxglove intolerance.
• State of shock.
• Chronic circulatory disorder.
• Atrial fibrillation.
• Heart failure.
• From 4 months it is recommended in combination with Diacarb to correct intracranial pressure. This combination treats glaucoma, epilepsy, edema, and gout.



Sport

It cannot be said that Asparkam has a significant effect on muscle growth. Therefore, in theory, this is not the drug of choice for sports. But, nevertheless, its popularity among athletes is great. This is explained simply: when gaining extra pounds, athletes eat a large amount of calories in the form of proteins, carbohydrates, and fats. At the same time, microelements account for a very small part of the diet. It is clearly not enough for normal cardiac activity. Moreover, a lack of potassium and magnesium leads to high fatigue due to metabolic imbalances. Asparkam in this case is irreplaceable.

Compact, easy to take and rich in essential K+ and Mg+ preparation:

1. Relieves the feeling of fatigue.
2. Replenishes micronutrient deficiencies.
3. Relieves muscle weakness.
4. Makes myocardial function stable.
5. Stimulates endurance.
6. Prevents AMI and stroke.

Body-building

As for bodybuilding, here Asparkam acts as an excellent metabolite. It is during strength training that its side effect of building muscle mass is in demand. Potassium has a positive effect on the speed of metabolic reactions, magnesium is involved in. In this case, cell growth occurs without fat accumulation and fluid retention in the body. This is a very important point, since during training athletes consume large amounts of water, which washes away microelements. This means that their replenishment becomes an urgent necessity.

Weight loss

The rationality of taking the drug is based on the same already familiar properties of magnesium and potassium. Mg+ is needed by the central nervous system, and K+ helps all muscles in the body. Together they correct the water-salt balance and remove swelling. Because of this feature, Asparkam is used for weight loss: removing fluid from the body allows you to lose weight. At the same time, the amount of fat deposits remains unchanged, so the drug has never been classified as a means of helping to lose weight. Taking it thoughtlessly is dangerous, since it is a metabolite, and metabolism is a very delicate substance. An excess of microelements has undesirable consequences, but in no way accelerates metabolic processes.

Contraindications and method of use

There are few contraindications, but they are important:

• Individual intolerance or sensitization of the body.
• Impaired function of the adrenal glands and kidneys.
• Myosthenia.
• Cardiogenic shock.
• Blockade 2-3 degrees.
• Metabolic acidosis.
• ARF and chronic renal failure, anuria.
• Hemolysis.
• Dehydration.
• Age up to 18.

The effect of Asparkam on the body has not been studied in detail. For this reason, it is used with caution during pregnancy and is not prescribed to children. Elderly patients are also at risk, since their metabolism is a priori slowed due to age-related changes. However, for diseases of the cardiovascular system, the drug can be taken without restrictions. The usual method is a couple of tablets three times a day after meals.

Side effects

Asparkam has not only positive side effects, but also negative ones. They are visualized by the following symptoms:

Feeling weak, tired, dizzy.

• Muscle weakness.
• Skin rashes.
• Nausea.
• Dyspepsia.
• Dry mouth.
• Bloating.
• Hypotension.
• Hyperhidrosis.
• Dyspnea.
• Vein thrombosis.

In addition, an overdose is possible, which manifests itself:

• hyperkalemia;
• hypermagnesemia;
• crimson cheeks;
• thirst;
• arrhythmia;
• convulsions;
• arterial hypotension;
• heart blockades;
• depression of the respiratory center in the brain.

These symptoms require consultation with a doctor. In general, long-term use of Asparkam requires monitoring of electrolyte levels, because:

1. the absolute safety of the drug has not been proven;
2. when combined with tetracyclines, iron and fluorine, the medicine inhibits their absorption (the interval between medications must be at least three hours);
3. there is a risk of developing hyperkalemia.

Compatibility

It has a different focus. From a pharmacodynamics point of view, combination with diuretics, beta blockers, cyclosporines, NSAIDs, heparin stimulates the development of asystole and arrhythmia. The combination with hormones stops this situation. Potassium ions reduce the negative effect of cardiac glycosides. Magnesium ions – neomycin, streptomycin, polymyxin. Calcium reduces the activity of magnesium, so such drugs must be combined with great caution, according to health indications.

Pharmacokinetics warns about the incompatibility of Asparkam with astringent and enveloping drugs, since they reduce the absorption of the drug in the digestive tube and recommends, if necessary, maintaining a three-hour interval between doses.

Comparison with Panangin

Potassium and magnesium are part of another popular medicine. We are talking about Panangina. Comparative characteristics of drugs are presented in the table.

Component	Pills		Solution
	Panangin	Asparkam	Panangin	Asparkam
Potassium aspartate	160 mg	180 mg	45 mg/ml
Magnesium aspartate	140 mg		10 mg/ml
Conversion to K+ ions	36 mg
Conversion to Mg+ ions	12 mg		3.5 mg/ml
Aids	Silica, povidone, talc, magnesium stearate, starch, macrogol, titanium salts, methcric acid copolymers.	Starch, talc, calcium stearate, Tween-80.	Injection water.	Water for injection, sorbitol.

Obviously, the active substances in both drugs are identical, the difference is in the cachet, which does not affect the medicinal properties of the drugs. However, Panangin has a film coating that protects the gastric mucosa and teeth from the chemical toxicity of the product. Therefore, Panangin is recommended to everyone who has problems with the digestive system, the price of which is several times higher than the cost of Asparkam.

Asparkam is considered one of the effective substances that improve the metabolic process. Due to the high content of potassium and ions, this medicine is prescribed for various diseases, including the regulation of intracranial. What is special about the drug, how does it affect the human body? How to take Asparkam so as not to harm your health? Let's look at these and other questions now.

Release forms, composition

At the moment, the drug is available in the form of tablets, a solution for intravenous injection in ampoules and in bottles (for droppers). Ampoules are 5 ml, 10 ml, 20 ml, and bottles are 200-400 ml. All presented forms of Asparkam contain magnesium and potassium aspartate (salts). Thanks to their excellent penetration, they act at the intracellular level.

Asparkam tablets consist of potassium and magnesium aspartate (174 mg each), corn starch, stearate, polysorbate-80, and talc. The solutions contain only water and sorbitol.

How does the medicine work?

Potassium and magnesium are involved in many biochemical processes occurring in the body. Therefore, taking tablets eliminates the deficiency of these elements and regulates metabolic processes. Potassium stimulates the synthesis of adenosine triphosphoric acid, which plays an important role in the development and vital activity of each cell. In addition, glycogen, protein and acetylcholine are produced. We can say that it is potassium that affects the speed of cell work and their ability to renew.

Magnesium is involved in metabolic processes and enhances the effectiveness of potassium.

Asparkam is a drug that is involved in regulating metabolic processes, replenishes the lack of potassium and magnesium in the body, and has an anti-inflammatory effect.

The effect of aspartate is most noticeable in the treatment of the heart. This drug has been part of the classical treatment regimen for many years. Taking Asparkam has the following effects:

• Normalizes metabolism in the heart muscle;
• Reduces the likelihood of myocardial injury;
• Improves the tolerance of cardiac glycosides;
• Helps increase cardiac endurance.

When to use

Many people are interested in what Asparkam helps with and is it really that effective? Quite often, doctors recommend using the drug without fail for heart failure. Due to the penetration of substances into the intercellular space and normalization of metabolism, positive changes are observed after some time. Indications for use of Asparkam are quite varied:

• Post-infarction period;
• Irregularities in heart rhythm;
• Digitalis intoxication (cardiac glycosides);
• Potassium and magnesium deficiency in the body;
• Prolonged and intense physical activity;
• Neurocirculatory.

Quite often, Diacarb and Asparkam are prescribed together to normalize intracranial, epileptic conditions, as well as edematous syndrome. Newborns are sometimes diagnosed with increased intracranial pressure, which is brought back to normal with the help of these drugs. At the same time, it is important to follow a certain regimen for taking Diacarb and Asparkam so as not to harm the child’s body. Reception of funds is allowed from the age of 4 months. The regimen, according to the instructions for use of Asparkam tablets, must be prescribed by the attending physician and strictly followed in order to eliminate the risk of disrupting the normal development of the baby.

Asparkam: instructions for use

Depending on the form of release, as well as the problem, the dosage and methods of using the drug vary.

Asparkam tablets must be swallowed without chewing. You just need to fill them with a small amount of water. Usually, when prescribing treatment, doctors recommend taking 2 tablets three times a day. The course lasts a month. Then you need to take a break for 2-3 months and repeat the intake again. When using the drug for preventive purposes (for potassium and magnesium deficiency), you need to drink 3 tablets a day immediately after eating. How long this course will last depends on the individual characteristics of the body. Some athletes take this remedy on an ongoing basis. At the same time, you need to take tests every month to monitor potassium levels and to prevent an overdose of the drug. There is no point in taking more than 6 tablets per day, since the excess is simply excreted from the body along with urine, and is not absorbed by the body. This increases the load on the kidneys, which does not always have a good effect on this organ.

While Asparkam tablets can be used as prophylaxis, intravenous solutions are prescribed only for treatment. The medicine is administered using a syringe or as a dropper directly into a vein. After opening the ampoule, the solution should be used immediately.

Important! If the solution becomes cloudy or there is a precipitate in it, then the substance should not be used under any circumstances. This indicates damage to the medicine.

The instructions for Asparkam indicate that in case of heart disease, the solution is administered intravenously at 10-20 ml for the first 5 days. In this case, the medicine is mixed with saline or dextrose. For a dropper or intravenous drip, use a 300 ml jar (2 times a day for 5 days).

Contraindications

The use of Asparkam has a number of limitations under which it is worth abandoning this drug. These include:

• Dehydration of the body;
• Metabolic acidosis;
• Myasthenia gravis in severe form;
• AV block;
• Chronic;
• Risk of edema;
• Tendency to excrete small amounts of urine;
• Individual sensitivity to aspartate.

In addition, the product cannot be used if the analysis shows an excess of active substances in the human body.

Asparkam is prescribed to children in its pure form extremely rarely. This usually happens if the infant is diagnosed with hypokalemia. In this case, injections are not used, unless there is a threat to the baby’s life, but only in tablet form. In this case, the dosage for a child under one year is ¼ tablet per day. The combination of Diacarb and Asparkam is more acceptable and is a kind of classic treatment for ICP in children. The duration of treatment is explained by the fact that Diacarb has a diuretic property, which makes it possible to neutralize the accumulation of potassium and magnesium salts in the child’s body. and phlebitis of the veins, as well as irritation of the walls of blood vessels (with intravenous administration).

Asparkam: analogues

Some people want to know if there is anything they can do to replace the drug. Pharmacies offer a wide range of analogues of this medicine.

In the domestic pharmaceutical market, analogues of Asparkam include drugs that also contain potassium aspartate and magnesium aspartate as active substances.

Such analogues of Asparkam include the following drugs:

• Aspangin;
• Asparkam –UBF;
• Asparkam Avexima;
• Pamaton;
• Forte;
• Potassium and magnesium aspartate.

Most often they buy Asparkam or Panangin. What makes the products distinctive is the dosage of active ingredients. Although the effects of the drugs are the same, Panangin does not cause drowsiness, which is an important point for some people. At the same time, the price of Asparkam is slightly lower. The advantage of an expensive analogue is considered to be a special shell that facilitates the swallowing process. Therefore, everyone chooses for themselves whether it is better to buy Panangin or Asparkam.

Many athletes prefer to take Riboxin Asparkam, which they need during periods of intense physical activity. Thanks to this drug, the myocardium is pumped and the heart becomes more resilient.