How to take Nystatin, instructions for use: rectal suppositories, tablets, ointments. Nystatin tablets: what helps, instructions for use, reviews

Nystatin is an antifungal antibacterial drug that is active against yeast-like fungi of the genus Candida.

Release form and composition

• Film-coated tablets: light yellow with a greenish tint, have a slight smell of vanillin (10 pcs in blister packs; 20 pcs in glass jars; 20 pcs in polymer jars, 1 jar in a carton pack) ;
• Ointment: yellow or brownish-yellow (30 g each in aluminum tubes);
• Vaginal suppositories: torpedo-shaped, yellow (5 pcs in blister packs, 2 packs in a carton pack);
• Rectal suppositories: torpedo-shaped, yellow (5 pcs in blister packs, 2 packs in a carton pack).

Active ingredient - nystatin:

• 1 tablet - 250 thousand or 500 thousand units (action units);
• 1 g of ointment - 100 thousand units;
• 1 vaginal suppository - 250 thousand or 500 thousand units;
• 1 rectal suppository - 250 thousand or 500 thousand units.

Excipients:

• Tablets: OPMC, basic magnesium carbonate, calcium stearate, tropeolin O, titanium dioxide pigment, MC-16, tween-80, potato starch, vaseline oil, lactose, vanillin;
• Ointment: medical vaseline and anhydrous lanolin;
• Vaginal suppositories: propyl ester of paraoxybenzoic acid, witepsol W-35, witepsol H-15 and food citric acid;
• Rectal suppositories: propyl ester of paraoxybenzoic acid, witepsol W-35, witepsol H-15, vaseline oil and food citric acid.

Indications for use

For tablets and ointments:

• Therapy of candidiasis of internal organs;
• Treatment of candidiasis of the mucous membranes and skin;
• Prevention of candidiasis during long-term therapy with antimicrobial agents, especially in debilitated and malnourished patients.

For vaginal suppositories:

• Treatment of vaginal candidiasis;
• Prevention of fungal complications during local antimicrobial therapy.

For rectal suppositories:

• Treatment of candidiasis of the lower intestines;
• Prevention of fungal complications in the pre- and postoperative period.

Contraindications

For all dosage forms:

• Peptic ulcer of the stomach and duodenum;
• pancreatitis;
• Impaired liver function;
• Pregnancy;
• Hypersensitivity to the drug.

Method of application and dosage

In tablets, Nystatin should be taken orally, with candidiasis of the internal organs - regardless of the meal. Recommended doses:

• Adults: 500 thousand units 4-8 times a day, with generalized candidiasis, the daily dose can be increased to 6 million units;
• Children over 4 years old: 250 thousand units - 500 thousand units 4 times a day;
• Children 1-3 years old - 250 thousand units 3-4 times a day.

The duration of treatment is from 10 to 14 days, if necessary, after 7 days the course is repeated.

Nystatin ointment is used for candidiasis of the mucous membranes and skin. Its thin layer is applied to the affected areas daily 2 times a day for 7-10 days. If necessary, the ointment is combined with the tablet form of the drug.

Vaginal suppositories should be inserted deep into the vagina (after hygiene procedures), 1 pc. 2 times a day - in the morning and in the evening. The duration of therapy is 10-14 days. If necessary, repeated courses of treatment can be prescribed.

Rectal suppositories should be injected deep into the rectum, 1 pc. 2 times a day - in the morning and in the evening. The duration of treatment is also 10-14 days. If necessary, repeated courses of treatment can be prescribed.

Side effects

• Digestive system: when taking tablets and using rectal suppositories - nausea, vomiting, diarrhea;
• Allergic reactions: fever, chills and pruritus;
• Other: risk of developing resistance (requires discontinuation of the drug).

special instructions

In the event of side effects, the dose of Nystatin should be reduced or discontinued altogether.

There is no need to interrupt vaginal suppository therapy during menstruation. 4.9 - 23 votes

The main active ingredient of the drug Nystatin is a polyene antibiotic element. The principle of action of this element of Nystatin is based on its binding to sterol molecules. The latter, in turn, are part of the cell membrane of the fungus.

Composition and form of release

Release form

• tablets of 250,000 IU and 500,000 IU;
• ointment;
• vaginal suppositories;
• rectal suppositories.

The composition of the tablets

Nystatin tablets are coated with a light yellow color with a slight smell of vanilla.

• One tablet of the drug contains 250,000 units or 500,000 units active ingredient.
• Auxiliary components are lactose, calcium stearate, magnesium carbonate, potato starch, titanium dioxide pigment, petroleum jelly, vanillin flavor.

Composition of candles Nystatin

Nystatin is available in the form of rectal and vaginal suppositories.

Vaginal suppositories Nystatin They are torpedo-shaped and light yellow in color. Two types of vaginal suppositories are produced: in the equivalent of 250,000 units and 500,000 units. Auxiliary substances are propyl ester of parahydroxybenzoic acid, citric acid, witepsol H-15 and W-35.

Composition of Nystatin ointment

Nystatin in the form of an ointment is used to treat candidiasis of the skin and mucous membranes.

• 1 g of ointment contains 100,000 units main active ingredient.
• excipients in this case, it is anhydrous lanolin and medical vaseline.

Storage: List B. Tablets should be stored in a dry and dark place at a temperature of 18 to 20 degrees above zero. Other forms of the drug are stored in the refrigerator at a temperature not exceeding 5 degrees.

Indications for the use of Nystatin

• candidiasis of the mucous membranes, skin, organs of the digestive system, vagina;
• antibiotic treatment;
• external use of antibacterial agents, for example, during the treatment of genital organs;
• preoperative and postoperative period in surgical interventions.

Contraindications

• pancreatitis;
• violations of the liver;
• ulcer after taking the remedy;
• individual intolerance to the components of the drug;
• During pregnancy and breastfeeding.

Side effects

Nystatin is not toxic and in most cases is well accepted by the body, however, there are cases of the following side effects:

• lack of appetite;
• diarrhea;
• nausea, which may be accompanied by vomiting;
• allergic reactions in the form of fever, itching, chills.

When the drug is discontinued, all side effects disappear.

Instructions for use

Nystatin has an antifungal and fungistatic effect. It is an antifungal drug and belongs to the group of polyenes. Shows particular activity against yeast-like fungi of the genus Candida. When using the drug, absorption from the gastrointestinal tract is very poor. When taken locally, absorption into the systemic circulation does not occur at all. Also, the cumulation process does not go through. The process of excretion of Nystatin occurs along with feces.

Method and dosage of tablets

Tablets can be taken both inside in the usual way, and prepare a solution from them. When prescribing, the composition must be taken into account in order to avoid individual intolerance to the drug.

Treatment of adults with nystatin

With candidiasis of the internal organs, an adult patient needs to take 500,000 units of the active substance three times a day, regardless of food intake. According to the instructions, the tablets should be swallowed whole, chewed or crushed in any other way is not recommended. The course of taking Nystatin tablets is about 10-14 days, depending on the degree of damage.

With constant relapses, the courses of treatment should be repeated periodically, making an interval of 14-21 days between them. The dosage is then increased to 6,000,000 units in 24 hours. In the treatment of stomatitis, the Nystatin tablet does not need to be swallowed orally. It should be put on the cheek and wait until it completely resolves. A single dose in this case is 500,000 units of the active substance. The drug should be taken only after eating and thoroughly brushing your teeth. The number of procedures per day is from 3 to 5.

Since the drug has a direct effect on the mucous membrane of the gastrointestinal tract, therefore, Nystatin is effective in the treatment of candidiasis of the digestive tract. For this purpose, Nystatin is taken in the amount of 1-2 tablets in the equivalent of 500,000 IU of the active substance 4 times a day. Duration of application is 14 days or more.

Method and dosage of suppositories

The instructions note that it is necessary to administer Nystatin vaginal suppositories only after hygiene procedures, using 1 suppository for one procedure. For a day it is necessary to carry out two such procedures, in the morning and in the evening. The course of treatment is from 10 to 14 days, depending on the severity of the disease. After the full course, control laboratory tests are carried out, which can show the presence of a fungus and require a repeat of the treatment.

Rectal suppositories Nystatin are injected into the rectum deep enough, 1 suppository twice a day. One procedure should be carried out in the morning, the second - after 12 hours. The course of treatment is from 10 to 14 days. The composition of rectal suppositories is completely similar to vaginal suppositories.

Method and dosage of ointment

For treatment, areas affected by the fungus should be covered with a thin layer twice a day. The full course of treatment is at least a week. This method of using Nystatin can be combined with oral administration of tablets.

Nystatin during menstruation

When using Nystatin suppositories during the monthly effect of the treatment, there will be no effect, since the active substance does not have time to act on the Candida-affected areas and is excreted with menstrual flow.

Nystatin for children

The medicine is quite popular in pediatrics for the treatment of candidiasis. Oral thrush, which often affects breastfed babies. For treatment, a special solution is prepared on the basis of the drug. Grind 1 tablet with 250,000 IU of the active substance into powder and mix with a solution of vitamin B 12. Lubricate the affected areas of the mouth with the resulting solution using gauze. If it is impossible to take a vitamin, it can be replaced with purified water.

The dose of Nystatin depends entirely on the age of the child. Patients up to a year are prescribed 100-125 thousand units of the active substance 3-4 times a day. Children up to three years old 250 thousand units 3-4 times a day. Children under 13 years of age are prescribed a dose of 250 or 400 thousand three times a day. Adolescents need to take 250 or 500 thousand units of the active substance 3-4 times in 24 hours.

During pregnancy and lactation

According to the official instructions during pregnancy and lactation, the use of Nystatin in any form is contraindicated.

Overdose

Cases of drug overdose, regardless of the form of release, have not been identified.

Interaction with other drugs

The peculiarity of the passage of Nystatin through the body when taken orally in the form of tablets, the number of medications with which it interacts is limited:

• Tetracycline. In combination with this drug, Nystatin has a positive effect on the effect of tetracycline on the body. The antifungal and antimicrobial effect of both drugs is enhanced.
• The action of Clotrimazole in combination with Nystatin is reduced.
• The effect of the drug is enhanced when taken simultaneously with Polymyxin and Nifuratel, as well as Chymotrypsin.
• The effect of the drug is reduced when combined with the use of all indirect anticoagulants, such as Coumadin or Warfarin.
• Reduce the effect of Nystatin and bactericidal antibiotics.
• The effectiveness of taking oral contraceptives, which include estrogen, while using Nystatin, is significantly reduced. It also increases the risk of heavy bleeding between menstrual cycles.

Domestic and foreign analogues

Amphoglucamine

It is used to treat fungal diseases of the digestive system and internal organs. It is especially active against yeast-like fungi, as well as mycoses, which are systemic in nature. This analogue is administered orally after meals twice a day. The course of treatment is at least 10 days. If necessary, the course of treatment should be repeated after laboratory tests.

Amphotericin B

This drug has an antifungal effect on the body against yeast-like fungi, pathogens of systemic mycoses. Amphotericin B is poorly absorbed from the digestive system, and is also completely non-toxic when taken in other ways. Indications for taking the drug are fungal diseases, the treatment of which with other antifungal drugs was unsuccessful. This analogue is administered by intravenous drip for 6 hours, the intervals between doses should be at least 24 hours. In the case of the appointment of an ointment, apply the drug in a thin layer twice a day for two weeks.

This drug shows high efficiency in the treatment of lesions of yeast-like fungi such as Candida. Can be used to treat children from the age of two years.

Mycoheptin

An antifungal drug that is used to treat visceral mycoses. Treatment with the use of Mycohepatin should be carried out under the strict supervision of a doctor who, throughout the course of treatment, controls the level of concentration in the blood of urea, creatinine.

Price in pharmacies

The price of Nystatin in different pharmacies can vary significantly. This is due to the use of cheaper components and the pricing policy of the pharmacy chain.

Read the official information about the drug Nystatin, the instructions for use of which include general information and a treatment regimen. The text is provided for informational purposes only and is not a substitute for medical advice.

The drug "Nystatin" refers to antifungal agents. It is mainly used to treat infections such as yeast-like fungi - candida, as well as to prevent diseases caused by them. For example, candidiasis of various localizations caused by the suppression of the flora of the gastrointestinal tract during antibiotic treatment. Especially in the treatment of "Tetracycline", "Neomycin" and other drugs. For preventive purposes, "Nystatin" is also prescribed to patients with weakened immune systems.

The mode of action of this drug is the destruction of the cell membrane, getting inside the cell and then destroying it from the inside. It takes some time for Candida to adapt to Nystatin. If the treatment is delayed, the drug loses its effectiveness. Therefore, if the treatment of a fungal disease or the prevention of the latter is prescribed for use, it is extremely important.

The forms of release of the drug are different, since it acts directly on the area of ​​​​active growth of candida. "Nystatin" in the form of tablets or granules for dilution with water (for babies) is used to treat candidiasis in the gastrointestinal tract. In the form of vaginal suppositories, the drug is used to prevent and treat vaginal candidiasis, which is popularly called thrush. Another form of release - rectal suppositories - is necessary for the treatment of colon candidiasis. And, finally, the last form is Nystatin ointment. Its use is the treatment of skin areas affected by the fungus.

Such a variety of release forms is due to the fact that "Nystatin" is poorly absorbed in the gastrointestinal tract, as a result of which it cannot fight fungi that affect the mucous membrane of the respiratory system, mouth, as well as vaginal fungal infections. It should not be taken uncontrollably as it has side effects. Diarrhea, abdominal pain, nausea and vomiting - this is a list of such side effects that Nystatin can cause. Instructions for use determines the doses of the drug required in the treatment of candidiasis and its prevention, and also clearly indicates in which case it is preferable to use certain forms of release of this drug.

In particular, the instructions indicate in what quantity and for how long Nystatin should be used for various types of candidiasis. Rectal suppositories are used twice a day for 1-2. They are introduced into the anus after cleansing the rectum naturally or with an enema. The duration of treatment is 1.5-2 weeks. Vaginal suppositories "Nystatin" are inserted into the vagina in the same amount and over the same period of time. At the same time, the instructions stipulate that when used simultaneously with clotrimazole, "Nystatin" reduces the effectiveness of this drug.

Tablets are taken orally. Depending on the severity of the disease, adults are prescribed 250 or 500 thousand units. active substance 3 or 4 times a day, children under the age of one year - 125 thousand units, from one year to five years - 250 thousand units each, children under 13 years old are invited to give the usual adult dose, but it is necessary to divide it for more receptions. With particularly complex diseases, it is allowed to take up to 6,000 thousand units.

Cases of allergic reactions to "Nystatin" are known. Instructions for use prohibits taking it to pregnant and lactating women, as well as to all other patients in the presence of body sensitivity to this drug. Moreover, in recent years, quite a lot of other drugs have appeared that successfully replace Nystatin in the fight against fungal diseases, the spectrum of action of which is wider.

It is known that "Nystatin" is necessary in the treatment of antibiotics only in cases where the patient's body is weakened by a serious illness. For example, patients with HIV infection or cancer patients. In other cases, the human body is able to cope with fungal infections on its own, without the use of the drug "Nystatin". The instructions for use also indicate that the period of treatment with the drug should last at least 10-14 days, since if these terms are violated, there is a possibility of developing resistant types of fungi that are not sensitive to it. In this case, the use of the drug must be stopped immediately.

It must be remembered that when using "Nystatin" or any other antifungal agent, it is recommended to combine them with the intake of dietary supplements, which include various vitamin complexes. This will enable the immune system to cope with the disease much faster.

One of the cheapest pharmaceutical drugs to combat thrush is nystatin tablets. What does this remedy help with, what are its contraindications, how effective and safe is it? Why do patients today often make a choice not in favor of Nystatin? And can it be used to treat candidiasis in children?

Ageno problem? Can Nystatin compete with new drugs?

Nystatin is a polyene antibiotic, that is, it acts on fungal cells, but is not active against bacteria. The drug destroys the cell membrane of fungi, which leads to their death. It has been used as an antifungal agent since the 1950s and is used today to treat related infections of the skin, mouth, esophagus, and vagina. It is effective against yeast-like fungi Candida and Aspergillus. The main active ingredient of this fungicide is nystatin. The composition of the ointment also contains lanolin and petroleum jelly.

The main advantages of this drug, thanks to which it has not left the pharmacological market for more than half a century, are low toxicity, local action and affordability. But its effectiveness has become lower over time, as the fungi have developed resistance to it.

WhenIs Nystatin indicated?

When can Nystatin tablets be used? Here's what they help with:

• prevent the development of candidiasis after antibiotic therapy, including topical application;
• prevent intestinal candidiasis in the preparation of surgery and the postoperative period;
• treat thrush of the vagina and organs of the gastrointestinal tract;
• relieve candidiasis of the mucous membranes of the skin.

INin what cases is it forbidden to use this tool?

• a woman who is pregnant or breastfeeding a baby;
• the patient suffers from pancreatitis and ulcers;
• a person has been diagnosed with severe liver damage;
• with increased individual sensitivity to nystatin.

Howaccept?

Most often, Nystatin is used in tablets for thrush. How to take them? You can drink both on an empty stomach and after eating. The tablet must be swallowed whole. To defeat thrush, you must complete a full course of treatment, and it ranges from 10 to 14 days. It is not recommended to stop taking the medicine at the first signs of improvement in the condition, since in this case there may be a relapse.

The instructions for the drug Nystatin contain such recommendations for the use of tablets for thrush in adults: 250 thousand units. from 6 to 8 times a day or 500 thousand units. 3 to 4 times a day. With generalized candidiasis, the standard dose can be increased by 2 times. In chronic thrush, treatment is carried out in 2-3 courses with a two-week break.

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With candidiasis of the oral cavity, the following scheme is used: 1 table. (500 thousand units) placed on the cheek and kept there until completely absorbed. Before taking the medicine, ensure oral hygiene. Use 1 tab. 3-5 p. a day before meals.

ABOUTWhat undesirable consequences does the manufacturer warn?

Side effects from taking the drug are limited to disorders of the digestive system and allergic reactions:

• when taking tablets and using rectal suppositories, indigestion and stools are possible, unexpressed pain in the abdomen;
• fever, fever, itching, skin rash;
• with prolonged treatment, there may be a decrease in the effectiveness of the drug, since the fungi form resistance to it.

Nystatinin pediatrics

The described antifungal drug is also prescribed for small patients, because it does not enter the systemic circulation. Usually the medicine is used externally as a treatment for thrush of the skin and mucous membranes. But Nystatin tablets are also used to treat children. The instruction prescribes to prepare a composition for treating the oral cavity from them: 1 table. 250 units grind, mix with 1 ml (1 ampoule) of vitamin B12 (or boiled water at room temperature).

When taken orally, children are given 1 table. from 3 to 4 p. in a day. The daily dose for a child is calculated using the following formula:

• babies one year old - tab. 100-125 thousand units, total dose - 400-525 thousand. units;
• from 1 to 3 years - 250 thousand rubles units, put on - 750-1000 units;
• 3-13 years - 250 or 400 thousand rubles units at1reception;
• adolescents over 13 years old - 250-500 thousand rubles each units

"Notthe strongest, but sometimes only he helps ": reviews of Nystatin

Despite the huge variety of antifungal drugs, Nystatin tablets are still used for thrush. Reviews about its effectiveness are mixed. Nystatin helps to achieve a positive result only if it is prescribed after taking a bacteriological smear. During this analysis, the sensitivity of fungi to various active substances is determined. If the smear showed that the bacteria are “afraid” of nystatin, then you can safely buy an inexpensive drug in order to recover from an extremely unpleasant disease. If you take it, only focusing on the price, then the result may be unsatisfactory.

Many women do not like that Nystatin must be drunk for 10 or even 14 days, while new drugs allow you to say goodbye to candidiasis in just 1 day, after a single dose of the medicine. It is not very convenient to use, but it is well tolerated, less injurious to the liver and almost does not cause adverse reactions.

The medical preparation Nystatin is positioned for use as a means to combat fungal infection. Doctors quite often prescribe medication when diagnosing candidiasis in patients, provoked by fungi of the genus Candida and Aspergillus. The tool effectively copes with the defeat of pathogenic microorganisms of the oral cavity, skin, intestines and vagina.

The drug acts locally and does not penetrate into the systemic circulation, while it is also noted that the agent does not have any effect on the natural microflora of the body. If oral administration is indicated for Nystatin, then excretion is carried out almost completely unchanged through the defecation process.

The mechanism of action of the drug lies in the destructive ability directed against the cell membranes of fungal microorganisms. After the penetration of the active components into the cell, they lead to the suppression of its reproduction or complete death.

The main difference between Nystatin and competitors is that fungi do not develop resistance to it for a long period, which makes it possible to carry out treatment for as long as possible. It is also worth noting that the drug has several forms of release and a low level of toxicity. Due to this, it can be prescribed to patients of various age groups and categories. The only prohibition is individual intolerance to the constituent components and the period of bearing a child.

Form

Currently, there are several forms of the drug Nystatin: tablets, suppositories, granules and ointment. In the first case, the drug contains 250,000 or 500,000 units of the main component. The medicine is packaged in blisters of 10 pieces, and each pack contains 2 such palettes.

The concentration of the active ingredients of the drug Nystatin in the form of granules is 100,000 in each granule. The vials contain 7.5 grams, and the name of the medicine is Fungostatin.

In some cases, it will be more effective to use Nystatin ointment. The drug in this form contains 100,000 units of the active ingredient for each gram of the drug. The product is packaged in aluminum tubes of 15 or 30 grams.

Nystatin suppositories can be rectal and vaginal. In the first case, the package contains 10 suppositories at a concentration of 500,000 units of the active ingredient, in the second case, the concentration is 250,000 or 500,000, also 10 pieces per package.

Indications

As the instructions for Nystatin indicate, the drug in the form of tablets or granules can be used in the treatment of fungal infections of various etiologies, as well as for preventive purposes. The main indications for the appointment are:

1. Preventive therapy for the likely development of candidiasis if the patient has been taking antibiotics for a long time.
2. Preventive therapy before surgical treatment, which helps to prevent the development of intestinal candidiasis before and after the procedure.
3. Preventive therapy for the development of candidiasis of the vulva, if antibacterial drugs are used in the same way.
4. Therapy of candidal lesions of the intestines and stomach, as well as the vagina.
5. Therapy of candidiasis of the skin and oral mucosa.

It is also noted that the granular medication is used in pediatrics (a suspension is prepared from it). As for tablets, they can be taken either orally, or they can also be prepared as a solution, previously diluted with water.

Contraindications

Among the contraindications to the use of the drug Nystatin in therapy, the following are distinguished:

• pancreatitis;
• Erosive and ulcerative lesions of the mucous membrane of the stomach or intestines;
• Severe liver pathology;
• High level of sensitivity to the active and additional components of the product.

Nystatin is not prescribed during pregnancy, as well as during the natural feeding of the child.

Adverse reactions

After Nystatin, some negative consequences may develop:

1. Nausea, sometimes bouts of vomiting, loose stools, discomfort and pain in the abdomen, if the drug was taken orally;
2. Allergic reactions of various types when using vaginal suppositories;
3. Resistance of fungal microorganisms to the active substance and loss of therapeutic efficacy if the drug was taken for a long period of time;
4. Any oral form can provoke allergic reactions in the form of fever, chills, skin rashes and itching.

If any symptom has made itself felt, or their complex has developed, you should stop the prescribed therapy as soon as possible and report this condition to your doctor. The specialist will select a different antifungal drug, tell you how to use it. All symptoms disappear quickly after withdrawal.

Dosage

If the question arises as to how to take Nystatin, you should ask your doctor. Instructions for use contains standard recommendations for dosages and duration of treatment. These data can be adjusted depending on the effect of treatment, the age and condition of the patient, the diagnosis.

The use of Nystatin suppositories of the rectal or vaginal type must be made taking into account the daily dosage of 250 or 500 thousand units of the drug 2 times a day (preferably in the morning and evening).

When treating adult patients with a drug in the form of tablets, it is necessary to take 250,000 units of the drug 6 to 8 times a day. If there is no such dosage, then Nystatin 500,000 units can be used, but the frequency of administration will be 3 or 4 times. In the treatment of candidiasis of the generalized type, it is permissible to double the dose.

The ointment should be applied to the affected area twice a day, in a thin layer.

In pediatrics

The dosage of Nystatin for children is always calculated taking into account their age. When taken orally, the standard recommendations are:

• From 0 to 12 months - 100 or 125 thousand units of the drug three times a day;
• From 12 months to three years - 250,000 units three times a day;
• From three to 13 years - 250 or 400 thousand units three times a day;
• Over 13 years old - 250,000 or 500,000 units three times a day.

The manufacturer also draws the attention of parents to the fact that it is better to use the medicine in granules, since it will be more convenient to select a single amount of medicine this way. As the instructions for Nystatin describe to children, it can be taken if necessary to get rid of candidiasis of the oral cavity and other localization.

During pregnancy

Currently, during the period of bearing a child, the drug is practically not prescribed. In exceptional cases, Nystatin suppositories can be administered during pregnancy, but the dose should be adjusted by the attending physician.

As the instructions for use describe, the drug is prohibited in any trimester of fetal growth, however, if the potential benefit to the mother outweighs the risks of a negative effect of the drug on the fetus, then therapy may be prescribed by a gynecologist.

With thrush

The drug Nystatin for thrush is prescribed in the form of rectal or vaginal suppositories, as well as ointments and tablets. Before you start using suppositories, a girl should definitely carry out hygiene procedures. The introduction is performed in the vagina or anus.

Nystatin suppositories

In most cases, to eliminate the symptoms of thrush, it is necessary to take 500,000 units of the drug, but if the disease is mild, then the dose may correspond to 250,000. Suppositories are administered twice a day, preferably in the morning and evening. The duration of therapy is about 14 days, but can be increased by a doctor.

Do not use suppositories for menstrual bleeding.

Interaction

With a combination of Nystatin and Tetracycline, antifungal efficacy increases, but in tandem with Clotrimazole, on the contrary, it decreases. Increase the effect of the drug Polyximin and Nifuralet, Chymotrypsin.

Price

Depending on the form of release of the drug Nystatin, its cost will differ:

1. The price of tablets in a concentration of 250,000 and 500,000 is within 15 and 30 rubles, respectively (for 20 pieces);
2. Granules will cost about 400 rubles for a package of 7.5 grams;
3. Vaginal and anal suppositories cost 35 and 50 rubles for 10 pieces at a concentration of 2,500,000 and 500,000 units, respectively;
4. The price of an ointment for a tube of 15 and 30 grams is in the range of 30 and 40 rubles, respectively (the concentration is 100,000 units in each gram).

The data is based on the monitoring of pharmacies on the Internet. Depending on the region of purchase, they may differ.

Analogues

Among the substitutes, doctors most often prescribe such drugs: Vilprafen, Ofloxacin, Azitsin, Levomycetin and Macropen. The selection of analogues should be carried out exclusively by a leading specialist, and only after a thorough examination of the patient.

About the drug (video)