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Paracetamol tablets for children: instructions for use and dosage for different ages. Paracetamol tablets for children: instructions for use and dosage

active ingredient: paracetamol;

1 tablet contains paracetamol 200 mg or 500 mg;

excipients: corn starch, potato starch, gelatin, croscarmellose sodium, stearic acid.

Dosage form

Pills.

Tablets are white or almost white, flat-cylindrical, scored and chamfered.

Manufacturer name and location

PJSC "Lugansk Chemical and Pharmaceutical Plant".

91019, Ukraine, Lugansk, st. Kirova, 17.

Pharmacotherapeutic group

Analgesics and antipyretics. Paracetamol. ATS code N02B E01.

Analgesic, antipyretic. The mechanism of action is due to inhibition of prostaglandin synthesis due to inhibition of COX and other mediators of pain and inflammation mainly in the central nervous system, as well as a decrease in the excitability of the thermoregulation center of the hypothalamus.

After oral administration, it is quickly and almost completely absorbed from digestive tract, mainly upper sections intestines. The maximum concentration in blood plasma is observed 30-60 minutes after oral administration. Binding to plasma proteins is variable. Metabolized in the liver to form paracetamol glucuronide and sulfate. Penetrates the blood-brain barrier and is excreted into breast milk. The half-life is 1-4 hours. Excreted by the kidneys, mainly in the form of metabolites, less than 5% is excreted unchanged. In elderly patients, the clearance of paracetamol decreases and the half-life increases.

Indications for use

Major pain, including migraine and headache tension, back pain, rheumatic pain, muscle pain, periodic pain in women, neuralgia, toothache; relieving cold and flu symptoms such as fever, aches, and pain.

Contraindications

Hypersensitivity to the components of the drug, severe violations liver and/or kidney function, congenital hyperbilirubinemia, glucose-6-phosphate dehydrogenase deficiency, alcoholism, blood diseases, severe anemia, leukopenia.

Proper safety precautions for use

It is necessary to consult a doctor regarding the possibility of using the drug in patients with impaired renal and liver function.

Keep in mind that in patients with alcoholic liver damage, the risk of hepatotoxic action of paracetamol increases; the drug may affect the results laboratory research by blood glucose levels and uric acid.

Do not exceed the indicated doses.

Do not take the drug with other products containing paracetamol.

If symptoms do not go away, you should consult a doctor.

Use during pregnancy or breastfeeding

Pregnancy. Prescribing the drug during these periods is possible only if the expected benefit to the mother outweighs the potential risk to the fetus or child.

Breastfeeding period. Paracetamol passes into breast milk, but in clinically insignificant quantities. Available published data do not contain any contraindications for breastfeeding.

The ability to influence the reaction rate when driving a vehicle or working with other mechanisms

Directions for use and doses

The drug is intended for oral administration.

Adults and children over 12 years old: 500-1000 mg every 4-6 hours if necessary, with an interval of at least 4 hours between doses. No more than 4000 mg in 24 hours.

Children (6-12 years old): 200-500 mg every 4-6 hours if necessary, with an interval of at least 4 hours between doses. No more than 2000 mg in 24 hours. The duration of treatment is determined by the doctor individually.

Overdose

Liver damage is possible in adults who have taken 10 g or more of paracetamol, and in children who have taken more than 150 mg/kg body weight. In patients with risk factors (long-term treatment with carbamazepine, phenobarbital, phenytoin, primidone, rifampicin, St. John's wort or other drugs that induce liver enzymes; regular intake of excessive amounts of ethanol; glutathione cachexia (digestive disorders, cystic fibrosis, HIV infection, hunger, cachexia ) Taking 5 g or more of paracetamol may cause liver damage.

Symptoms of overdose in the first 24 hours: pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12-48 hours after overdose. Impaired glucose metabolism and metabolic acidosis may occur. At severe poisoning Liver failure can progress to encephalopathy, hemorrhage, hypoglycemia, coma and death. Acute renal failure with acute necrosis tubules may appear strong lumbar pain, hematuria, proteinuria and develop even in the absence of severe liver damage. Cardiac arrhythmia and pancreatitis were also noted.

With long-term use of the drug in large doses On the part of the hematopoietic organs, aplastic anemia, pancytopenia, agranulocytosis, neutropenia, leukopenia, thrombocytopenia may develop. When taking large doses from nervous system- dizziness, psychomotor agitation and disorientation; from the urinary system - nephrotoxicity ( renal colic, interstitial nephritis, capillary necrosis).

In case of overdose, an ambulance is needed medical care. The patient should be taken to the hospital immediately, even if there are no early symptoms overdose. Symptoms may be limited to nausea and vomiting or may not reflect the severity of overdose or the risk of organ damage. Treatment with activated charcoal should be considered if an excessive dose of paracetamol is used within 1 hour. Plasma concentrations of paracetamol should be measured 4 hours or later after administration (earlier concentrations are unreliable).

Treatment with N-acetylcysteine can be applied within 24 hours after taking paracetamol, but the maximum protective effect is obtained when it is used within 8 hours after administration. The effectiveness of the antidote decreases sharply after this time. If necessary, the patient is administered N-acetylcysteine intravenously according to the established list of doses. In the absence of vomiting, oral methionine may be used as an appropriate alternative in remote areas outside the hospital.

Side effects

Adverse reactions to paracetamol are very rare (< 1/10000):

allergic reactions: anaphylaxis, itchy skin, rashes on the skin and mucous membranes (usually a generalized rash, erythematous, urticaria), angioedema, multiform exudative erythema(including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome);

from the digestive tract: nausea, epigastric pain, increased activity of liver enzymes, usually without the development of jaundice;

from the outside endocrine system: hypoglycemia, up to hypoglycemic coma;

from the hematopoietic organs: anemia, sulfhemoglobinemia and methemoglobinemia (cyanosis, shortness of breath, pain in the heart area), hemolytic anemia;

respiratory system disorders: bronchospasm in patients sensitive to acetylsalicylic acid and other NSAIDs.

Interaction with other drugs and other types of interactions. The rate of absorption of paracetamol may be increased metoclopramide And domperidone and decrease cholestyramine. Anticoagulant effect warfarin and others coumarins may be exacerbated by concomitant long-term, regular daily use of paracetamol, with an increased risk of bleeding. Periodic use does not have a significant effect.

Barbiturates reduce antipyretic effect paracetamol.

Anticonvulsants drugs (including phenytoin, barbiturates, carbamazepine), which stimulate the activity of microsomal liver enzymes, can enhance toxic effects paracetamol on the liver due to an increase in the degree of conversion of the drug to hepatotoxic metabolites. At simultaneous use paracetamol with hepatotoxic agents increases toxic effect drugs for the liver.

Concomitant use of high doses of paracetamol with isoniazid increases the risk of developing hepatotoxic syndrome. Paracetamol reduces effectiveness diuretics.

Do not use simultaneously with alcohol.

Best before date

Storage conditions

No special storage conditions are needed. Store in original packaging. Keep out of the reach of children!

Package

Tablets 200 mg, 10 tablets in a blister; 500 mg tablets, 10 tablets in a blister or strip; 500 mg tablets, 10 tablets per strip, 5 strips per pack.

Among all antipyretic drugs used in childhood, the most popular is Paracetamol. It effectively reduces fever and helps relieve pain different localization. Especially for children's use This drug is produced in the form of a sweet suspension and rectal suppositories. Depending on how old the child is, ordinary tablets may be suitable for him.

Release form and composition

Tablets "Paracetamol" are produced in different pharmaceutical companies, so in pharmacies you can find not only a medicine with that name, but also tablets, the box of which has a mark about the manufacturer (such drugs are called "Paracetamol MS", "Paracetamol-LEKT", "Paracetamol-UBF" and so on).

Usually the solid form of the medicine looks like small round tablets, who have white, but there may also be a white-yellow or white-cream shade. They are packaged in blisters and sold in boxes of 10 or more. The main ingredient of any of these medications is also called paracetamol. Depending on its quantity per tablet, the medicine is made in two dosages - 200 mg and 500 mg. Abroad, tableted Paracetamol is also available in a dose of 325 mg.

Auxiliary components Medicines vary from company to company. Among them you can see gelatin, starch, povidone and other ingredients.

If a child has an intolerance to such substances, they should be specified in the annotation for the selected tablets.

Operating principle

After the tablets enter the stomach, paracetamol is absorbed quite quickly, after which this substance penetrates through the bloodstream to the brain tissue and affects the centers of pain and thermoregulation. In these centers, under the influence of such a compound, cyclooxygenases are blocked (these enzymes affect the synthesis of prostaglandins), resulting in painful sensations are eliminated, and body temperature returns to normal.

IN peripheral tissues the action of paracetamol is inhibited cellular peroxidases. Due to their presence, the drug has virtually no anti-inflammatory effect, but also has no side effects on water-salt metabolism And the pills also don’t have any effect on the gastric mucosa.

Indications

Tablets "Paracetamol" is used in various cases:

As an antipyretic medicine for elevated temperature body caused by vaccination, childhood infection, influenza or other illness.
As an analgesic if the pain is not expressed or moderate (for earache, headache, sore throat, toothache and others).

Is it possible for children?

Paracetamol tablets are not used in the treatment of patients under six years of age. If the child is not yet 6 years old, for example, he is only 2 or 4 years old, then instead of the solid form they give Paracetamol in suspension or use suppositories. Medicine in these forms is allowed from 3 months of age and is most often chosen for both children under 1 year and preschoolers. They are often used in children 7-8 years old or older if it is difficult for a child to swallow a tablet.

Contraindications

The tablets should not be given to young patients with the following characteristics:

Intolerance to paracetamol or any auxiliary component.
Peptic ulcer or erosive changes in the wall of the gastrointestinal tract.
Lack of glucose 6 phosphate dehydrogenase in the body.
Bleeding from the walls of the digestive tract.

In addition, the medicine is not used if the child has serious blood diseases, impaired liver function, or renal failure.

Side effects

Taking Paracetamol may cause itchy skin, rashes or other signs of an allergic reaction. IN in rare cases such tablets have a negative effect on hematopoiesis, gastrointestinal tract or liver function. If any side effects it is advised to discontinue the medicine, but the child must show it to a doctor immediately.

Instructions for use

Paracetamol is taken 1 to 3 times a day, swallowing the tablet 1-2 hours after meals and washing it down with water. The dosage is determined taking into account the patient's age. If, say, a child is 7 years old, then 200 mg can be given per dose, and for a 14-year-old child the single dosage is 500 mg. Age also affects the maximum permissible daily dose - it is 1.5 g for patients 6-9 years old, 2 g for children 9-12 years old and 4 g for adolescents 12 years old and older.

The interval between taking tablets should not be shorter than 4 hours. If the medicine is prescribed for pain, the duration of use is up to 5 days; longer treatment is possible only under the supervision of a doctor.

If the tablets are used for an antipyretic effect, then the course of administration should not exceed three days.

Overdose

If a child takes too many Paracetamol tablets, it will cause vomiting, stomach cramps, loose stool, etc. negative symptoms gastrointestinal irritation. A very large dose of the drug is dangerous for the liver, and since signs of damage to this organ do not appear immediately and can lead to serious consequences, a child with an overdose must be examined by a doctor (even if his health is fine).

Combination with other drugs

You should not combine the use of Paracetamol and other drugs based on the same active ingredient, because this will increase the risk of overdose. Without a doctor's prescription, it is also not recommended to give tablets together with other antipyretic drugs (for example, acetyl salicylic acid or ibuprofen).

Storage Features

The shelf life of the medicine may vary depending on different manufacturers and is usually 3 years or 5 years. It is recommended to keep the medication at home at temperatures up to +25 degrees, choosing a place for storing it that is inaccessible to children.

Dosage form: capsules, effervescent powder for the preparation of solution for oral administration [for children], solution for infusion, solution for oral administration [for children], syrup, rectal suppositories, rectal suppositories [for children], suspension for oral administration, suspension

Pharmacological action: Non-narcotic analgesic, blocks COX1 and COX2 mainly in the central nervous system, affecting the centers of pain and thermoregulation. In inflamed tissues, cellular peroxidases neutralize the effect of paracetamol on COX, which explains practically complete absence anti-inflammatory effect. The absence of a blocking effect on the synthesis of Pg in peripheral tissues determines the absence of negative influence on water-salt metabolism (Na+ and water retention) and the gastrointestinal mucosa.

Indications: Feverish syndrome in the background infectious diseases; pain syndrome (mild and moderate severity): arthralgia, myalgia, neuralgia, migraine, toothache and headache, algodismenorrhea.

Contraindications: Hypersensitivity, neonatal period (up to 1 month). With caution. Kidney and liver failure, benign hyperbilirubinemia(including Gilbert's syndrome), viral hepatitis, alcoholic liver damage, alcoholism, pregnancy, lactation, old age, early infancy(up to 3 months), glucose-6-phosphate dehydrogenase deficiency; diabetes mellitus(for syrup).

Side effects: From the outside skin: skin itching, rash on the skin and mucous membranes (usually erythematous, urticaria), angioedema, exudative erythema multiforme (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome). From the side of the central nervous system (usually develops when taking high doses): dizziness, psychomotor agitation and disorientation. From the outside digestive system: nausea, epigastric pain, increased activity of liver enzymes, usually without the development of jaundice, hepatonecrosis (dose-dependent effect). From the endocrine system: hypoglycemia, up to hypoglycemic coma. From the hematopoietic organs: anemia, sulfhemoglobinemia and methemoglobinemia (cyanosis, shortness of breath, heart pain), hemolytic anemia (especially for patients with glucose-6-phosphate dehydrogenase deficiency). With long-term use in large doses - aplastic anemia, pancytopenia, agranulocytosis, neutropenia, leukopenia, thrombocytopenia. From the urinary system: (when taking large doses) - nephrotoxicity (renal colic, interstitial nephritis, papillary necrosis). Overdose. Symptoms (acute overdose develops 6-14 hours after taking paracetamol, chronic - 2-4 days after exceeding the dose) acute overdose: dysfunction of the gastrointestinal tract (diarrhea, loss of appetite, nausea and vomiting, discomfort in abdominal cavity and/or abdominal pain), increased sweating. Symptoms of chronic overdose: a hepatotoxic effect develops, characterized by general symptoms(pain, weakness, adynamia, increased sweating) and specific, characterizing liver damage. As a result, hepatonecrosis may develop. The hepatotoxic effect of paracetamol can be complicated by the development of hepatic encephalopathy (thought disturbances, central nervous system depression, stupor), convulsions, respiratory depression, coma, cerebral edema, hypocoagulation, development of disseminated intravascular coagulation syndrome, hypoglycemia, metabolic acidosis, arrhythmia, collapse. Rarely, liver dysfunction develops at lightning speed and can be complicated by renal failure (renal tubular necrosis). Treatment: administration of SH-group donors and precursors for the synthesis of glutathione - methionine 8-9 hours after an overdose and N-acetylcysteine - after 12 hours. The need for additional therapeutic activities(further administration of methionine, intravenous administration of N-acetylcysteine) is determined depending on the concentration of paracetamol in the blood, as well as on the time elapsed after its administration.

Directions for use and dosage: Paracetamol 200 is taken orally, with a large number liquids, 1-2 hours after eating (taking immediately after eating leads to a delay in the onset of action). Adults and adolescents over 12 years of age (body weight over 40 kg) single dose- 500 mg; the maximum single dose is 1 g. The frequency of administration is up to 4 times a day. Maximum daily dose- 4 g; The maximum duration of treatment is 5-7 days. In patients with impaired liver or kidney function, with Gilbert's syndrome, in elderly patients, the daily dose should be reduced and the interval between doses should be increased. Children: maximum daily dose for children up to 6 months (up to 7 kg) - 350 mg, up to 1 year (up to 10 kg) - 500 mg, up to 3 years (up to 15 kg) - 750 mg, up to 6 years (up to 22 kg ) - 1 g, up to 9 years (up to 30 kg) - 1.5 g, up to 12 years (up to 40 kg) - 2 g. In the form of a suspension: children 6-12 years old - 10-20 ml (in 5 ml - 120 mg), 1-6 years - 5-10 ml, 3-12 months - 2.5-5 ml. The dose for children aged 1 to 3 months is determined individually. Frequency of appointment - 4 times a day; the interval between each dose is at least 4 hours. The maximum duration of treatment without consulting a doctor is 3 days (when taken as an antipyretic drug) and 5 days (as an analgesic). Rectally. Adults - 500 mg 1-4 times a day; maximum single dose - 1 g; maximum daily dose - 4 g. Children 12-15 years old - 250-300 mg 3-4 times a day; 8-12 years - 250-300 mg 3 times a day; 6-8 years - 250-300 mg 2-3 times a day; 4-6 years - 150 mg 3-4 times a day; 2-4 years - 150 mg 2-3 times a day; 1-2 years - 80 mg 3-4 times a day; from 6 months to 1 year - 80 mg 2-3 times a day; from 3 months to 6 months - 80 mg 2 times a day.

Special indications: If the febrile syndrome continues during the use of paracetamol for more than 3 days and pain syndrome for more than 5 days, a doctor’s consultation is required. The risk of developing liver damage increases in patients with alcoholic hepatosis. Distorts laboratory test results in the quantitative determination of glucose and uric acid in plasma. During long-term treatment painting control is required peripheral blood And functional state liver. The syrup contains 0.06 XE of sucrose per 5 ml, which should be taken into account when treating patients with diabetes.

Interaction with other drugs: Reduces the effectiveness of uricosuric drugs. Concomitant use of paracetamol in high doses increases the effect of anticoagulant drugs (decreased synthesis of procoagulant factors in the liver). Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants), ethanol and hepatotoxic drugs increase the production of hydroxylated active metabolites, which makes it possible to develop severe intoxications even with a slight overdose. Long term use Barbiturates reduce the effectiveness of paracetamol. Ethanol promotes development acute pancreatitis. Inhibitors of microsomal oxidation (including cimetidine) reduce the risk of hepatotoxicity. Long-term sharing paracetamol, etc. NSAIDs increase the risk of developing “analgesic” nephropathy and renal papillary necrosis, the onset of the terminal stage renal failure. Simultaneous long-term administration of paracetamol in high doses and salicylates increases the risk of developing kidney cancer or bladder. Diflunisal increases the plasma concentration of paracetamol by 50% - the risk of developing hepatotoxicity. Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.

Paracetamol is given to a child for high fever, headache and toothache. He is considered safe medicine, because even with a three-fold overdose it does not cause complications. However, like any medicine, Paracetamol has its own specifics, and must be treated with caution. Before treatment, you should carefully study the instructions for use of Paracetamol, special attention referring to the calculation of the dosage of tablets for children 1 year and older.

Composition and release forms of the drug

Paracetamol for children is an antipyretic and analgesic with a slight anti-inflammatory effect. Its effectiveness is especially high for viral infectious diseases; for bacterial diseases it helps little.

The therapeutic effect of the drug is based on inhibition of production chemical compounds, which are responsible for the development of inflammatory processes, stimulate an increase in temperature and the appearance pain syndrome. The analgesic and anti-inflammatory effect is achieved due to the effect of the drug on the cells of the central nervous system.

The advantage of the drug over other anti-inflammatory drugs is that it does not have any special irritant effect on the gastric mucosa. Paracetamol quickly enters the blood, where its highest concentration is achieved in the period from 30 minutes to one and a half hours - depending on the form of the drug. The drug is excreted from the body along with urine after processing in the liver within 4 hours.

Active substance The medicine bears the same name, it is also known as para-acetaminophenol. For children, Paracetamol is available in different forms:

Candles - they contain components that are safest for children. The drug administered rectally is absorbed into the blood more slowly than when swallowed (an hour and a half), which is why the effect occurs later, but it is longer lasting. Doctors may prescribe suppositories for treatment one year old child and even babies from 3 months.
Suspension – excipients include glycerol, sorbitol, flavorings and sucrose. Can be used from 1 month (only as directed by your pediatrician).

Syrup – contains ethanol (96%), excipients, flavorings, dyes. The maximum concentration in the blood is observed half an hour after ingestion. The product is recommended for ages from six months to 12 years.
Tablets or capsules – available in dosages of 200 and 500 mg. Children can be given from 3 years of age (subject to the dosage).
Effervescent tablets for preparing a solution.

IN lately Paracetamol, produced in the form of sweet syrups and suspensions, has gained particular popularity. By taking these drugs, along with active medicinal components, the baby receives huge amount flavorings, sweeteners, flavoring additives. They can provoke allergic reactions, while allergies to Paracetamol itself are very rare. This means that ideal option for small children - candles.

Indications for taking Paracetamol tablets (200 and 500 mg)

Paracetamol is effective for:

temperature caused by colds, flu, scarlet fever, measles, vaccinations, etc.;
headaches, including those caused by overexertion;
toothache (caries, teething, etc. (which medications can be given to a child for toothache?), etc.);
pain manifestations not associated with inflammation;
relief of symptoms of colds or flu such as fever, aches;
inflammation of the middle ear (otitis) as a complex therapy.

Paracetamol is used as an antipyretic and pain reliever. When is the drug contraindicated?

Like any medicine, Paracetamol has contraindications. These include:

allergy to the components of the drug;
serious problems with the kidneys and liver, which are involved in processing and removing drugs from the body in urine;
congenital hyperbilirubinemia, or Gilbert's syndrome - increased level bilirubin in the blood (a breakdown product of red blood cells);
some varieties severe infections(eg sepsis);
leukopenia (low white blood cell count);
blood diseases;
deficiency of the enzyme glucose-6-phosphate dehydrogenase;
severe anemia;
taking certain medications ( anticonvulsants, barbiturates, rifampicin, etc.);
inflammation of the rectal mucosa (for the use of suppositories).

Instructions for use of tablets

Although Paracetamol is effective in relieving fever and headaches, if you have a serious illness, it will not reduce the temperature.

Dr. Komarovsky calls this medicine a kind of marker: if the fever has decreased after taking it, there is a high probability that the disease is not dangerous - it is a common ARVI. If there is no effect from the drug, the problem is serious, you should urgently call a specialist.

Dosage for children of different ages

Paracetamol tablets are allowed for children over three years of age. For adults, the maximum daily dose is 60 mg/kg. In what dosage is Paracetamol given to children:

norm from 3 to 6 years – 100-200 mg at a time;
from 6 to 12 years – 1-2 tables. (200-400 mg);
adolescents and adults – 500 mg.

Before giving your baby a tablet, you should read the instructions and find out how much paracetamol it contains. If the doctor has prescribed a dose of 100 mg, the 200 mg capsule should be divided into 2 parts, the tablet containing 500 mg should be divided into 5 parts. A slight overdose is not dangerous.

How many times a day can you take the drug?

According to the instructions, children should drink Paracetamol every 4 hours. More frequent use is not recommended because better effect there will be no effect from increasing the dose multiplicity. Paracetamol is absorbed into the blood 30 minutes after entering the stomach and begins to act actively. Maximum concentration and positive effect reached after 2 hours - the temperature begins to decrease.

It is recommended to take the drug every 4 hours; less often - possible, more often - no

As soon as Paracetamol enters the child's blood, the kidneys and liver begin to process it and remove it from the body. After 4 hours, 50% of the substance leaves the body, which leads to a decrease in the effect of the drug. The medicine is completely eliminated after 8 hours. As you recover, the need for frequent use the medication disappears, so the interval can be increased to 5-6 hours.

Duration of treatment

The doctor should tell you how long the course of treatment with Paracetamol will last. At high temperatures, the product can be taken for no more than 3-5 days. Whether it is worth continuing to use the drug and what dose is prescribed per day is determined by the doctor. Irrational use of the drug can cause necrosis of liver cells, kidneys and other problems.

Long-term use of Paracetamol for headaches and toothaches is not advisable, since it can relieve symptoms, but not cure the underlying disease. Diseased teeth need to be treated as soon as possible, as they not only cause pain to the baby, but can also negatively affect growth permanent teeth. An unreasonable headache should alert you, as it may indicate serious illnesses and be a reason for further diagnosis.

Side effects

The use of Paracetamol rarely causes side effects. However, their absence cannot be completely ruled out after taking the medicine.

In some cases, the drug may cause gastrointestinal upset

They may appear:

nausea, diarrhea, vomiting, stomach pain, dizziness;
a decrease in the level of leukocytes, erythrocytes, platelets in the blood (extremely rare);
liver pathologies;
allergies;
bronchospasm.

Overdose

The child should not take more than 60 mg of active substance per kg of body weight per day. A dosage of 150 mg/kg is toxic for a baby. This means that if a baby weighs 20 kg, he can die if he takes 3 g of paracetamol during the day.

Overdose causes side effects and signs of intoxication: pale skin, vomiting, sweating, loss of consciousness. If the liver fails, jaundice is possible, hepatic coma, death. Acute renal failure may occur, which will make itself felt by lower back pain, pancreatitis, arrhythmia, and the appearance of protein and blood in the urine.

Analogues of the drug

Paracetamol is included in many medicines– Coldrex, TeraFlu, Antigrippin, Panadol, Antiflu, Caffetin, etc. Their main differences are excipients, manufacturer, price.

If the medicine does not help, it is replaced with an analogue with another active component. Similar action have medications based on ibuprofen - Nurofen, Ibufen, etc. In any case, you must remember: even the most harmless medications cannot be prescribed to yourself in order to avoid unpredictable consequences.

When a child has a fever, the first medicine that parents use to stabilize the condition is paracetamol, and this is not without reason.

The World Health Organization included this drug in the list of the most effective, safe and cost-effective medicines.

Let's take a closer look at the instructions for using Paracetamol tablets for children (200 and 500 mg): recommended dosages for fever, is it possible to give medicine to a child at all and how much, what to do if the norm is exceeded?

Description and action

Paracetamol is not a new pharmaceutical. It has been used for treatment since 1893. This is one of the safest non-steroidal anti-inflammatory drugs.

The drug has almost no effect on cyclooxygenase, or COX, produced in peripheral organs and tissues. That's why it has fewer side effects than other NSAIDs.

So, the medicine does not irritate the gastric mucosa, does not lead to disruption of water-mineral metabolism.

At the same time, the drug affects COX, which is produced by the brain, which determines the antipyretic and analgesic properties, the ability to influence inflammatory processes the drug has almost none.

Paracetamol is well absorbed from gastrointestinal tract , therefore, tablet dosage forms along with rectal suppositories most preferred.

The drug acts quickly, and within 30 minutes after administration its highest concentration is observed inside. The effect lasts up to 4 hours.

The lack of effect when using Paracetamol is a reason for immediate appeal for medical help.

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Release form and composition

The drug is available in tablets of 0.2 g and 0.5 g(200 and 500 mg). This form is recommended for children over 6 years of age due to possible overdose.

Can be used from 2 years of age, although other forms are preferable at this age.

By physical properties It is a pure white or creamy, pinkish crystalline powder that is soluble in alcohol and insoluble in water.

Indications

The drug is used if:

the temperature rises to 38 °C and above (age up to 5 years), to 38.5 °C (age after 5 years) and lasts for at least 4 hours;
complaints of toothache, headache, muscle pain.

Paracetamol is effective for viral infections(ARVI).

The product is also used for chicken pox, measles, flu, rubella, teething, after injuries and burns.

It doesn't help with bacterial infections, complications of ARVI, the effect is short-lived or absent.

Contraindications

The list of contraindications is small in comparison with other drugs. This includes:

individual intolerance;
age up to 2 years;
diseases of the gastrointestinal tract with the formation of ulcers and erosions, stomach bleeding, inflammation, active bleeding;
progressive pathologies of the kidneys, liver, severe forms of failure of these organs;
intolerance acetylsalicylic acid or other NSAIDs;
hyperkalemia ( increased content potassium in the blood).

How much and how to give

Maximum course of treatment is:

up to 6 years - 3 days;
after 6 years - 5 days.

What dose of Paracetamol tablets is needed for children and how to take the medicine correctly?

When prescribing doses, they are guided not by age, but by the weight of the baby. 10–15 mg is prescribed per 1 kg active substance.

Thus, a single dosage of Paracetamol in tablets for children weighing 10 kg is 100–150 mg (0.1–0.15 g), or 1/2–3/4 tablets with a dosage of 200 mg (0.2 g).

Re-appointment should be no earlier than after 4-5 hours. 4–5 doses are allowed per day.

Safe daily dose - up to 60 mg/kg body. This means that a child weighing 10 kg should not be given more than 3 tablets of 200 mg per day.

For teenagers over 12 years of age who weigh more than 40 kg, maximum single dose - 1 g (5 tablets of 0.2 g), daily - 4 g (20 tablets of 0.2 g).

Directions for use, special instructions

The drug is given orally. After eating, 1-2 hours must pass, otherwise absorption will slow down. Drink a lot clean water. If the child is small, then the tablet is crushed into powder.

Paracetamol is an emergency medicine that does not cure, but only eliminates the manifestations of the disease. If the cause of the disease is not eliminated, the fever and pain will return.

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Reception features

The question of what dose of paracetamol to give a child in tablets must be decided after consultation with a doctor. When treating, take into account the following features of admission:

if there is liver disease, the dose is reduced;
when using other drugs simultaneously, you need to make sure that they do not contain paracetamol;
Do not give your child alcohol-containing products, as alcohol enhances the absorption of the medicine.

Overdose

Taking the drug in a single dose of more than 150 mg/kg of the child’s body weight causes severe, and in some cases fatal, liver damage.

Stages of poisoning:

For development liver failure indicate:

neuropsychic disorders (feels sleepy, dizzy, speech impaired, hallucinations);
pain in the right side under the ribs;
swelling, abdominal enlargement;
jaundice;
bleeding;
heart rhythm disturbances;
failure of the function of other organs.

Death from an overdose occurs within 3–5 days.

In case of overdose, wash the stomach, give to the patient activated carbon, cause ambulance. The antidote for paracetamol is acetylcysteine.

In case of liver failure, hospitalization is carried out, treatment is symptomatic. In severe cases, a liver transplant may be required.

Children suffer from poisoning more easily than adults, especially those under 6 years of age., due to the characteristics of metabolism. In mild cases, treatment is carried out at home.

How can an overdose occur?

Drug dosage 0.2 mg is safe. So, for a child weighing 10 kg to become poisoned, he needs to take 1.5 g of the drug per day orally, which is 7.5 tablets.

Exceeding the dose occurs for several reasons:

parents in a hurry did not pay attention to the content of the active substance;
other drugs were given at the same time with paracetamol;
increased the frequency of administration;
the baby accidentally took the medicine on his own because it was in an accessible place.

Side effects

Although Paracetamol is well tolerated in most cases, he calls side effects :

IN recent years scientists started talking about harm and toxicity.

Studies have shown that children who were frequently prescribed paracetamol at 1–3 years of age develop allergic diseases -

Eczema, allergies.

Safety is maintained with infrequent use.

There is also evidence that at long-term use paracetamol more than 1 tablet per day, if the total amount of medication taken is 1000 or more tablets over a lifetime, the risk of developing severe forms analgesic nephropathy (kidney disease), which leads to end-stage renal failure (complete loss of kidney function).

Drug interactions

Paracetamol interacts with other drugs, which may affect the safety of therapy.

The following effects may be observed:

promotion harmful effects on the liver, reducing the antipyretic effect of paracetamol - in combination with barbiturates of antiepileptic drugs, rifampicin;
enhancing the effect of coumarin derivatives, salicylic acid, caffeine, codeine;
an increase in the level of methemoglobin - with simultaneous use with phenobarbital.

Do not combine Paracetamol tablets with other means that contain this active ingredient (Parafex, Paravit, Cold-flu, Coldrex and others).

Average price

The average price of Paracetamol 0.2 g, 10 tablets is 6 rubles.

Storage conditions and periods

The expiration date is indicated on the packaging(usually 36 months). Store the drug at a temperature no higher than 25 °C, choosing a place inaccessible to minors.

Recipe for purchase medicine not needed.

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Reviews

Now you know how to give paracetamol tablets to children, how much medicine to give and what dosage to follow to avoid an overdose. Let's also consider reviews from parents.

Natalya, 28 years old: “Paracetamol helped our son at first. Then they gave me pills, the effect lasted for an hour. Then she gave Nurofen syrup and put suppositories with paracetamol.”

Elena, 30 years old: “Paracetamol has no effect on my baby’s body. I gave the pill, waited an hour and a half, and the effect was zero.”

Yulia, 32 years old: “For bacterial acute respiratory infections, I use Ibuprofen or Paracetamol: the first acts in a quarter of an hour, the second in an hour. For viruses, I give either one or the other drug, both work within an hour. If the temperature persists, we alternate these remedies.”

Among popular means To combat fever and pain in children, there are tablets containing paracetamol as the active substance. It is considered the most effective and safe for the child’s body.

Paracetamol-based drugs have three main properties: they relieve fever, inflammation and pain.

Advantages of the drug:

Fights high body temperature during colds, ARVI or flu. It can be given to children aged 2 months, after first reducing the permissible dose.
The decrease in temperature begins quickly and has long lasting effect- its further increase is not observed.
In some children, high fever may be accompanied by seizures. Paracetamol is also allowed for such unpleasant symptoms.
Reduces or eliminates pain. For example, dental or headache.
Other medications can be given at the same time. Nurofen contains ibuprofen as an active ingredient, so alternating them is allowed.

It should be taken into account that paracetamol eliminates only the symptoms of the disease, but is not intended for its treatment. The underlying cause of pain or fever should be identified and children treated with other medications.

Dosage of the drug

Paracetamol comes in three main forms: suppositories, tablets and syrups. You can buy a product at the pharmacy where this active ingredient is in pure form- Panadol for example. Panadol tablets, in addition to the active substance, contain sodium bicarbonate, which creates an alkaline environment in the body. Thanks to this, Panadol works faster.

Candles

They are administered rectally - into anus child. Before the procedure, you must first wash your hands. Place the child, turn him on his side, bend his legs and press them to his tummy. Slowly and carefully introduce the suppository. The active substance is absorbed by the intestinal walls and has quick effect at high temperature. For children under three months, the dosage is selected only by a doctor..

At the pharmacy you can find the following dosage of the drug:

from 3 months to a year, 0.08 gram suppositories are prescribed;
from 1 year to 3 years – 0.17 grams;
from 3 years to 6 – 0.33 grams;
starting from 6 years and older, two suppositories of 0.33 grams are prescribed.

You should not use more than 4 suppositories per day.

Pills

They are allowed for children starting from two years old. The child is given medicine, previously crushed and diluted in water. Children's paracetamol tablets are available in a dosage of 200 mg:

from 2 to 6 years, 1/2 tablet is prescribed at a time;
from 7 to 12 years, one full tablet is allowed;
Children over 12 years of age are allowed to take two tablets at a time.

In some cases this form Can also be taken by children up to one year old. Especially when it comes to a very high temperature with the appearance of seizures. In such cases, the use of the medicine is allowed in the following dosage:

from birth to 3 months, the dosage is 10 mg per kilogram;
from 3 months to a year, the maximum daily dose is 120 mg;
from one year to 2 years, the maximum daily dose is 150 mg.

Syrup

This dosage form has a liquid consistency and good taste, so children swallow it easily. Syrup can be given as early as two months. Sometimes doctors, taking into account the child’s condition at the time of illness, can prescribe syrup in the first weeks of life.

The kit includes a convenient dispenser syringe or measuring spoon, with which the exact amount of suspension is measured. The drug should not be diluted with water; it is better to give the child something to drink after taking it.

The exact dosage is drawn according to the divisions on the syringe:

from birth to 6 months, the dosage is calculated by the attending physician;
from 6 months to one year maximum dosage is 5 mg, minimum – 2.5 mg;
up to 3 years, the dosage is 5 – 7.5 mg;
from 3 to 6 years – the maximum dosage is 10 mg;
from 7 to 12 years – about 15 mg.

The medicine begins to act within 30 minutes after administration. At high temperatures, the syrup is given for no more than three days. As a painkiller, the drug can be taken for up to five days.

An analogue of the drug Paracetamol is Panadol. It is approved for children aged 3 months and older. Panadol Baby can be used to relieve fever, inflammation and pain. Can also be used after vaccinations.

Features of application

Before giving medicine to a child, you should consult your pediatrician. He will appoint correct dosage and will tell you about the rules of admission.

The dosage of the drug depends on the age and weight of the child.
Paracetamol tablets should be given to relieve fever at intervals of 6 hours. No more than four times a day.
In children under the age of one year, the temperature should be reduced if it rises above 38 degrees.
Paracetamol should not be given to infants for more than three days. Their internal organs are not yet fully formed, which creates an extra load on the liver.
This antipyretic should not be given for prophylaxis.
For a small child, the tablet must first be dissolved in water.
You should not use a tablet intended for adults - it is impossible to accurately determine the dosage.
Nurofen has more irritating effect on the stomach than Panadol. Therefore, it is better to stop at the last drug.

Tips for taking medications that contain paracetamol

There are various shapes release of this active ingredient. It can be in candles, syrups or in the form of a suspension. They are best suited for children under one year old.
To reduce the harmful effects on the liver, the medicine should be given after meals.
Dangerous for child's body The dosage is 150 mg per kilogram of weight.
An overdose can be recognized by the following symptoms: the skin becomes pale, nausea and vomiting appear. In this case, you need to urgently consult a doctor.

Sometimes, when the temperature is high and falls heavily, children are prescribed two drugs at the same time: Nurofen and Paracetamol. These drugs are given at intervals. Nurofen acts quickly and the effect is longer lasting.

You can combine Nurofen with paracetamol at the same time. In this case, half the dose is taken from each drug.

Contraindications

Overdose of the drug is not allowed and frequent use, which negatively affects the functioning of the liver. Nausea and vomiting appear.
Individual intolerance to the components of the drug. Allergic reactions may occur.
For children under two years of age, paracetamol should be given with caution - the drug can cause asthma.
Do not give two paracetamol-based medications at the same time. This will lead to poisoning of the body. Can be given with other antipyretics, for example, Nurofen.
An overdose can occur if the interval between doses of the medication is not observed. It's better to combine drug treatment with folk remedies.
The drug is contraindicated for diseases such as anemia, hyperbilirubinemia, and disorders of the kidneys and liver.

If at least one symptom appears, then it should be replaced this medicine to another. Nurofen causes allergies less often and causes less harm internal organs. Just like paracetamol, Nurofen is available in the form of suppositories, tablets and syrup.

There are many medications in pharmacies that contain paracetamol. Panadol is available in tablets, suppositories and syrups. Panadol Baby is specially produced for the little ones

Do not forget that all medications must be kept away from children. It is better to store medications for adults separately from children's ones, so that during the period of illness the child does not mix up medications due to increased anxiety.

Before giving paracetamol to a child, you should consult your doctor. It is he who will tell you which dosage form is best to choose and whether it is worth combining it with other antipyretics. Calculate the exact permitted dosage. Only by following the rules and recommendations can you reduce side effects and overdose.

With the development of colds, the first sign in children is an increase in temperature. If pediatricians prohibit giving children antipyretics at elevated temperatures, then if the thermometer readings are above 39 degrees, you should definitely resort to medication. One of the most effective ways Reducing high fever is a medicine called Paracetamol. Is it possible to give children Paracetamol in tablets, at what age should it be used, as well as the specific dosage of the drug, we will find out further.

Dosage of Paracetamol tablets

Paracetamol for fever is available in three forms: tablets, syrup and rectal suppositories. All forms of the drug are intended to reduce high fever. Paracetamol in certain forms of release should be given to a child depending on his age.

The main advantage of the drug in tablet form is its low cost, especially when compared with syrups. Many parents resort to medication in tablets only when the child turns 5 years old. It is at this age that a baby can swallow a pill without it getting stuck in the throat. Some parents are in no hurry to resort to using the drug in tablets, and give it from the age of 6.

The instructions for use indicate that children can be given the drug in tablet form at 2 years of age and older. However, it is important to note that at 2-3 years of age it is preferable to give syrup to children, and before 2 years of age it is best to use rectal suppositories. It is possible for young children to take Paracetamol in tablet form if they have a fever, but the tablet should initially be crushed and then given to drink with sweetened water.

Important to know! At high temperatures, children can be given Paracetamol no more than 4 times a day. The break between subsequent doses should be 4-6 hours. The duration of therapy should not be more than 3 days.

How to give Paracetamol tablets to children depends on their age and weight. Paracetamol for children with fever should be calculated based on the following dosage: per 1 kg of baby’s body weight, 10 mg of the drug is required. For a baby whose weight is 10 kg, 100 mg of the drug will be required.

Interesting to know! The drug can bring down a child’s temperature approximately 25-30 minutes after administration.

Dosage of Paracetamol 200 mg in tablet form

We have already found out whether Paracetamol can be given to children. It is only worth noting that if a child of 5-6 years old cannot swallow the tablet whole, it should be divided into parts or crushed into powder. It is not recommended to give the drug to infants in tablet form, so it is better to resort to rectal suppositories.

The drug Paracetamol 200 mg is very popular. The tablets are quickly absorbed by the body, so within 30 minutes a positive effect from its use occurs. In addition, the tablets do not contain flavorings or dyes, which can harm the baby if taken orally. You can not only bring down the temperature with the drug, but also reduce pain symptoms for toothaches, headaches, neuralgia and osteochondrosis. Let's find out in more detail how to lower the temperature with the help of the medicine in question.

It is not recommended to give antipyretic tablets to children under two or three years of age. Moreover, if the doctor has prescribed the use of the drug for the baby in this form, then you can resort to such treatment.
Children under the age of five or six years can be given the medicine in tablet form, but only at a dosage of 100 mg. Paracetamol can be given to a child at this age no more than 2 times a day.
Children under 12 years of age are given the drug at a dosage of 200 mg. The dosage of Paracetamol depends primarily on weight, so before giving the medicine to your baby, you need to read the instructions.
Older children from 12 years of age can be given Paracetamol at a dosage of 500 mg.

The instructions indicate that children under 12 years of age can be given tablets with a dosage of 500 mg, but the dose must be calculated correctly. It is also important to note the fact that before giving medicine at a temperature of 38 and above, you should consult a specialist. Your local or attending physician will tell you how to take it, how much of the drug you need, and how often you can take it.

Important to know! You need to lower your baby’s temperature if the thermometer shows above 39 degrees. An adult can begin to reduce the fever if the mark exceeds 39-39.5 degrees.

Can children take medicine in tablets?

Doctors say that children can take pills if certain conditions are met.

If the thermometer reading is above 38.5-39 degrees. For children under 3-4 years old, it is necessary to reduce the fever above 38-38.5 degrees.
There is no need to rush to bring the fever down below 38. If the thermometer readings are above 38, you should initially try to use folk method, for example, wiping with a vinegar solution. If the fever continues to rise or lasts four hours or more after the parents have tried all methods to reduce it, then this medicine can be given.
Is it possible for a child to take Paracetamol, and in what dosage should it be used for high fever, toothache and weakness. It can not only be given, but it is also necessary. If the drug does not bring down the fever, but the pain during teething has decreased, then you need to consult a specialist or replace the medication with Ibuprofen.

Paracetamol is excellent remedy in the fight against high fever in children different ages. With age, the form of the drug can be changed, and the name of the drug can remain the same, but on one condition that the drug gives a positive effect.

Is it dangerous to overdose on a medicine?

The instructions indicate that in case of an overdose of the drug you should consult a doctor. We found out how to give Paracetamol to children, but why is an overdose so dangerous? this tool? In fact, Paracetamol is one of the safest antipyretic drugs. In case of a slight overdose, this will not affect the baby’s health in any way, especially if the medicine is used in a single dosage.

Important to know! Before using Paracetamol in tablets for children with fever, you should familiarize yourself with the dosage of the medicine, and then select it according to the baby’s weight.

Depending on the excess amount of the drug, the baby may experience side symptoms from an overdose. Excessive doses of the drug are set negative impact to organs such as the kidneys and liver. Most often, with a regular overdose of the drug, liver damage develops, as well as hepatic comas.

Symptoms of a Paracetamol overdose include:

nausea and vomiting;
abdominal pain;
problems with stool;
the occurrence of drowsiness.

Most dangerous sign overdose is intoxication. In this case, you definitely need to go to the hospital for help. Therefore, the question of whether a child can take Paracetamol should be answered in such a way that the medicine is not only allowed, but also necessary if necessary. In order not to make a mistake with the dosage, you must carefully read the instructions or consult a specialist.

At what months can you give your baby goat milk? At what age can you give your baby coffee with milk?

Paracetamol is a common, popular medicine that is often prescribed to relieve headaches and reduce fever. The drug acts as an analgesic, has an antipyretic and mild anti-inflammatory effect.

Paracetamol is included in the list essential drugs WHO. He is also on the vital list necessary medications, approved by the Government of the Russian Federation.

The drug is available in various dosage forms. At the pharmacy you can buy an injection solution, syrup, capsules, etc. Most often, tablets with different dosage main substance - 200 and 500 mg.

In what cases is Paracetamol 200 mg used, the instructions for use contain information about what its dosage should be for children and adults - you will learn about this today on the pages of the Popular About Health website.

Indications for use of tablets

The instructions for the product will clearly indicate the indications for use of the drug, namely:

Fever caused by an infectious disease.

Painful feeling light or medium degree expressiveness.

Toothache, headache, migraine.

Arthralgia, myalgia, as well as neuralgia and algodismenorrhea.

When using Paracetamol as a pain reliever, you need to know that it will be effective only for mild or moderate pain. At severe pain it is better to use other drugs, for example, Nurofen, Tempalgin, Nalbufin Serb, Tramadol, etc.

Paracetamol 200 for children - indications

High temperature due to infectious diseases (bacterial or viral).

The period of teething to alleviate the baby's condition.

Feverish conditions of various etiologies.

Headache, toothache, muscle pain.

Injuries, skin damage, including burns.

Flu, colds accompanied by temperature.

Neurological pathologies (as part of complex treatment).

Dosage Paracetamol 200 mg for children:

For children under 3 years of age - a single dose of no more than 15 mg per 1 kg of body weight. For example, if the child weighs less than 7 kg, the dose per dose should not exceed half a tablet.

For children over 3 years of age, the drug is also prescribed based on their body weight. By medical indications The child can be given 1-2 tablets at a time. Daily dosage for children should not exceed 1-2 g, in 3-4 doses.

The necessary dosage regimen for children, Paracetamol 200 mg, in a particular case, is determined by the doctor individually, taking into account age, diagnosed disease and condition of the body. little patient.

Dosage for adults

For adults, Paracetamol 200 mg, as well as for adolescents over 12 years of age, if the body weight is 40 kg or more, the permissible single dosage per dose should not exceed 1 g of the drug. Adults are usually prescribed the drug to take 500 mg at a time. Reception - up to 4 times per day. The maximum daily dose is 4 g.

Treatment is usually carried out for 5 to 7 days. The final dosage regimen and treatment period are determined by the doctor, taking into account the diagnosis and individual characteristics patient.

Instructions Paracetamol 200 mg also informs that patients with severe kidney and liver diseases, suffering from Gilbert's syndrome, as well as elderly patients can take the drug only in a reduced dosage, with an increased interval between doses.

Contraindications

The drug is contraindicated in people with hypersensitivity to drug components, newborn children (up to 1 month).

With caution: in case of liver and kidney failure, viral hepatitis, as well as in alcoholism and alcohol impairment liver.

Also, with caution, the drug is prescribed to elderly patients, pregnant women and children under 3 months.

Side effects

Possible allergic manifestations - skin rash, urticaria and angioedema.

With long-term use of the drug in high dosages - 4000 mg per day or more, hepatotoxic effects, nausea, discomfort, painful sensations in the stomach.

Hemolytic and aplastic anemia. Methemoglobinemia, pancytopenia, thrombocytopenia and agranulocytosis may develop.

Papillary necrosis, pyuria, and interstitial nephritis.

May go down blood pressure. Hypoglycemia, dyspnea, and vasculitis may occur.

Subject to availability similar conditions While taking the drug, you should stop treatment with Paracetamol and consult a doctor.

In conclusion, it should be noted that the drug is not intended for long-term use. The need to take tablets for more than one week should be discussed with your doctor.

It must be remembered that the medicine has contraindications and many side effects. Therefore, before you start using Paracetamol 200 mg, you should carefully study the instructions for use and do not exceed the recommended dosages.