Cycloferon in ampoules: what you need to know about the action and use of the injection solution. Instructions for use

The composition of the injection solution of Cycloferon includes:

• active substance - meglumine acridone acetate (acridone acetic acid) - a low molecular weight interferon inducer with a wide spectrum of bioactivity;
• excipient - water for injection.

The main cells producing interferon after administration of Cycloferon are T- and B-lymphocytes, macrophages. Depending on the type of infection, one or another part of the immune system begins to predominate.

In addition, the drug stimulates the formation of granulocytes, activating bone marrow stem cells.

Cycloferon is highly effective against influenza viruses, herpes, papilloma, hepatitis, tick-borne encephalitis, human immunodeficiency virus, cytomegalovirus and others.

The use of medication for acute viral hepatitis prevents the disease from becoming chronic.

In case of HIV infection at the stage of primary manifestations, immunity indicators stabilize.

The effectiveness of Cycloferon as an immunotherapy in the complex treatment of acute and chronic bacterial infections - chlamydia, urogenital infections, bronchitis, pneumonia, neuroinfections, chlamydia, postoperative complications has been clinically confirmed.

In the case of rheumatic and systemic connective tissue diseases, the drug suppresses autoimmune reactions and has an anti-inflammatory and analgesic effect.

1.5-2 hours after the injection, the maximum level of the drug in the blood is observed. After a day, the substance is already contained in trace quantities.

Cycloferon is characterized by low toxicity and does not cause mutations or allergic reactions. The drug quickly dissolves in the tissues of the body and is excreted from the body naturally (through the kidneys) without consequences. With long-term therapy, the substance also does not accumulate in organic tissues.

Indications for use

Possessing a wide range of biological activity (immunomodulatory, antiviral, anti-inflammatory, etc.), Cycloferon solution is effective in the treatment of a number of diseases:

• Leyme disease;
• herpetic infection;
• chlamydial infections;
• HIV infection (stages 2A - 2B);
• flu;
• ARVI;
• secondary immunodeficiency;
• meningitis;
• cytomegalovirus infections;
• encephalitis;
• viral hepatitis A, B, C, D;
• rheumatic and systemic connective tissue diseases (systemic lupus erythematosus, rheumatoid arthritis);
• degenerative-dystrophic diseases of the joints (deforming osteoarthritis, etc.).

Directions for use and dosage

Cycloferon solution can be administered into the body through intramuscular and intravenous injections. The ampoule is opened immediately before administration of the drug.

In most cases, injections are given once a day according to the following scheme:

• one injection on the 1st and 2nd day of the course;
• then on days 4, 6 and 8 of treatment;
• then at 11 and 14, 17 and 20, 23 and 26, 29 days.

• cytomegalovirus infection - no more than 10 injections, the total dose of which should not exceed 2.5 g of solution.
• neuroinfection - from 10 to 12 PMG injections every other day in combination with a course of etiotropic therapy.
• viral hepatitis - pre-injections of 400 mg for three months.
• rheumatic diseases - 4-5 injections every other day for 3-4 months with a two-week break in the middle of the cycle.

The dosage of Cycloferon solution for children is calculated according to body weight - approximately 6-10 mg of medication per 1 kg of child weight. The specific treatment regimen is determined only by the pediatrician.

• nausea and vomiting;
• panic attacks and insomnia;
• skin rashes;
• general malaise.

Contraindications

Cycloferon injections are contraindicated for:

• decompensated cirrhosis of the liver;
• kidney and liver dysfunction;
• the presence of individual intolerance to the components of the drug;

• pregnant and lactating women;
• children under 4 years of age.

Patients with erosive or ulcerative pathologies of the duodenum or stomach in the acute stage, gastritis, duodenitis, as well as people prone to allergies should take the drug with caution.

Cycloferon - injections

Cycloferon is a drug that is available in various forms, including for injection (injections). Cyfloferon injections are prescribed to enhance immunity and prevent diseases in cases where the body’s immune defense is weakened and is not able to overcome the disease on its own, and the risk of infection or complications is high. Cycloferon injections are often recommended by doctors for flu and colds, and for herpes virus infection. What else is Cycloferon prescribed for in the form of injections, how this drug acts on the body, what are its contraindications and side effects, we will consider further.

Effect of Cycloferon injections and indications for their use

The drug in question is based on an active substance such as meglumine acridone acetate. This component, upon penetration into the human body, stimulates the production in tissues and organs containing elements of lymphoid tissue (lymph nodes, liver, spleen, intestines, tonsils, etc.) of a large amount of their own interferon. As is known, the protein interferon is one of the main “defenders” of the body from foreign agents (infectious agents, malignant cells), therefore, the higher its content, the more effectively pathological processes will be suppressed. In addition, Cycloferon causes activation of other protective cells in the body (granulocytes, T-lymphocytes, T-killers), suppresses autoimmune reactions, has anti-inflammatory, analgesic and antitumor effects.

• HIV infections;
• serous meningitis and encephalitis;
• tick-borne borreliosis;
• hepatitis of viral etiology;
• herpes virus infection (including cytomegalovirus);
• acute intestinal infections;
• chlamydial infection;
• syphilis;
• mycoplasmosis;
• rheumatoid arthritis;
• systemic lupus erythematosus;
• deforming osteoarthritis;
• influenza and ARVI;
• tumor processes.

Thanks to the use of Cycloferon for most diseases, a decrease in the intensity of symptoms, the duration of the disease, and the prevention of the development of various complications are achieved. In the treatment of bacterial infections, this drug significantly increases the effectiveness of prescribed antibiotic therapy. During the season of outbreaks of respiratory viral diseases, the use of Cycloferon will help protect the body from infection and the development of severe forms of infection.

Contraindications and side effects of Cycloferon injections

In most cases, injections with this drug are well tolerated, because Cycloferon does not have toxic, carcinogenic or mutagenic properties. In rare cases, the following adverse effects may occur:

• allergic reactions (including urticaria, angioedema);
• hyperemia and swelling at the site of drug administration;
• increase in body temperature.

Normal phenomena are the appearance of mild pain, short-term burning and slight redness of the skin at the injection site. However, all of the above side effects usually do not require discontinuation of the medication.

As for contraindications, Cycloferon also has them, but there are not many of them:

• pregnancy;
• breastfeeding period;
• cirrhosis;
• hypersensitivity to the components of the drug;
• children up to four years of age.

It should also be noted that in no case should you start using this medicine on your own, without a doctor’s prescription.

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Instructions for use of Cycloferon in ampoules for injections

To treat exacerbations of colds and inflammations, Cycloferon injections are used - instructions for use of which notify the patient in detail about the composition, method of administration and the required dose. Injections with the medication must be given strictly in accordance with the indications, observing the daily dosage of the solution to avoid side effects. Familiarize yourself with the procedure for using Cycloferon in the form of injections.

Cycloferon in ampoules

According to the pharmacological classification, Cycloferon refers to drugs that stimulate the immune system and its processes. This is an anti-inflammatory, antiviral immunomodulator drug used to treat inflammation caused by infections. Cycloferon is administered by intramuscular injection, observing the dose, time of administration and strictly according to the instructions.

Compound

The active component of Cycloferon is meglumine acridone acetate, which in terms of acridone acetic acid contains 250 mg per ampoule. The auxiliary ingredients are methylglucamine (193 mg per 2 ml injection), purified water for injection. In addition to ampoules for injections, the following are also produced:

• Cycloferon tablets - with methylglucamine and acridoneacetic acid, methylcellulose, calcium stearate;
• antiviral liniment - in addition to the active component, it contains catapol and propylene glycol.

Release form

The drug is used intravenously or intramuscularly, using Cycloferon ampoules made of colorless or brown glass - a transparent yellowish solution for injection 12.5%, five pieces in a blister pack. Tablets, coated, soluble in the intestines, are sold in 10 or 50 pieces inside a cardboard pack and blister, liniment 5% is enclosed inside metal or plastic tubes with a volume of 5 or 30 ml.

Pharmacodynamics and pharmacokinetics

If you are interested in Cycloferon injections, the instructions for use state that the immunostimulating drug is a low-molecular-weight interferon inducer. It has antiproliferative, antitumor, immunomodulatory, antiviral, anti-inflammatory effects. Cycloferon promotes the release of interferons inside organs and tissues with lymphoid elements, activates bone marrow stem cells, stimulates the production of granulocytes, T-lymphocytes and natural killer cells.

This helps to correct the status of immune cells in case of immunodeficiency of the body, eliminate microbes and chlamydia. The drug is credited with anticarcinogenic and antimetastatic effects, it prevents the formation of tumors. When applied to the area, it corrects local immunity. It reaches its maximum concentration in the blood after a couple of hours, and after a day only traces of it remain. With long-term use, it does not accumulate in the body; the half-life is 4-5 hours.

Cycloferon - application

For adults, Cycloferon injections are used intramuscularly according to the indications indicated in the instructions. Among them:

• HIV infection;
• neuroinfections: serous meningitis, encephalitis, tick-borne borreliosis;
• viral hepatitis;
• herpes virus, cytomegalovirus infection;
• secondary immunodeficiency, accompanied by acute or chronic fungal, chronic bacterial infections;
• chlamydia, urethritis therapy;
• rheumatoid arthritis, systemic lupus erythematosus, autoimmune diseases;
• deforming osteoarthritis, other degenerative-dystrophic diseases of the joints.

Cycloferon in ampoules - instructions for use

Adults are administered Cycloferon intramuscularly or intravenously once a day according to instructions every other day. The course of therapy depends on the severity of the disease:

• for cytomegalovirus and herpetic infections – 10 injections of 250 mg (total dose 2.5 g), it is more effective to treat at the beginning of an exacerbation;
• for neuroinfection - 12 injections of PMG along with etiotropic therapy, repeat the course if necessary;
• chlamydial infections - 10 injections of 250 mg, repeated later, use a combination of Cycloferon with antibiotics;
• acute viral hepatitis - 10 injections of 500 mg, with a prolonged course - repeat every other day;
• chronic hepatitis - 10 injections of 500 mg, then maintenance therapy three times a week for three months along with interferons and the effects of chemotherapy, repeat a day later;
• at stages 2A-2B of HIV infection - 10 injections of 500 mg intramuscularly, maintenance regimen - once every three days for 2.5 months, repeat the course after 10 days;
• immunodeficiency conditions, prevention of influenza, respiratory diseases - 10 intramuscular injections of 250 mg, a repeat course of immunotherapy components after six months to a year;
• systemic and rheumatic diseases of connective tissue - four courses of five injections of 250 mg with a 24-hour break;
• degenerative joint diseases - two cycles of five injections of 250 mg with a break of days

Cycloferon for children

Indications for the use of Cycloferon by children according to the instructions are age over four years, viral hepatitis, herpes, HIV. The drug is prescribed intramuscularly or intravenously once a day, the daily therapeutic dose is considered to be 6-10 mg/kg body weight:

• acute viral hepatitis - 15 injections, repeated the next day;
• chronic hepatitis – 10 injections, maintenance regimen three times a week for three months;
• HIV – 10 injections, support every three days for a course of three months;
• manifestations of herpes - 10 injections; if the virus remains active, a maintenance regimen is used once every three days for a month.

Special instructions

If you have been prescribed Cycloferon injections, the instructions for proper use contain a paragraph of special instructions. Rules for using the drug:

• do not use intramuscular medication during pregnancy or breastfeeding;
• Do not take the medication if you have liver dysfunction;
• if the patient has abnormalities in the thyroid gland, treatment with Cycloferon is carried out under the supervision of an endocrinologist;
• simultaneously with injections in the treatment of influenza and acute respiratory infections (prevention of ARVI), symptomatic therapy is carried out to increase immunity;
• the medicine does not affect the speed of psychomotor reactions.

Drug interactions

According to the instructions for use and patient reviews, Cycloferon is compatible with any medications used in the treatment of diseases for other indications. It increases the effect of interferons and nucleosides, does not affect the effectiveness of chemotherapy drugs and antibiotics, but reduces their side effects. The drug also reduces the risk of the negative effects of interferon therapy for influenza. It is prohibited to drink alcohol during injection treatment.

Contraindications

According to the instructions for use of Cycloferon injections, the drug cannot be used parenterally with the following contraindications:

• decompensated cirrhosis of the liver;
• pregnancy, lactation;
• hypersensitivity to components;
• children under four years of age;
• according to reviews, with caution in case of thyroid diseases and under the supervision of an endocrinologist.

Side effects and overdose

The instructions for use of Cycloferon state that cases of overdose with parenteral injections have not been described, so there is no need to be afraid of the occurrence of unpleasant symptoms. Side effects of the drug include an extremely low likelihood of allergic reactions. If they occur, you should get medical help. It is recommended to discontinue treatment or adjust the dose.

Terms of sale and storage

Cycloferon in ampoules is included in list B, dispensed from pharmacies with a prescription when prescribed by the attending physician. The drug is stored in a dry place, protected from light and children, at a temperature range of degrees. For transportation, you can freeze the medication, which does not affect the change in its properties. It should be defrosted at room temperature. If the color of the solution has changed and a precipitate has formed, the medication should not be used. The shelf life is three years.

Analogues

Based on the active substance and therapeutic effect, the following analogues of Cycloferon are distinguished:

Price of Cycloferon

Ampoules can be purchased in online pharmacies or bought in a regular department. The cost depends on the pricing level of the trading enterprise. Approximate prices for all forms of the drug are shown in the table:

Price when purchasing online, rubles

Price on the pharmacy shelf, rubles

Ampoules 12.5%, 2 ml, 5 pcs.

Tablets 150 mg, 20 pcs.

Tablets 150 mg, 50 pcs.

Tablets 150 mg, 10 pcs.

Liniment 5%, 30 ml

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Reviews

Anastasia, 34 years old

I am planning a third pregnancy, so two months ago I donated blood to test for infections. I was diagnosed with a viral infection, which, as the doctor told me, can be successfully treated with a course of interferons. I was prescribed Cycloferon injections - the injections are painless but effective. During the course I got rid of the infection and can easily get pregnant.

After an unsuccessful picnic, I had to see a doctor because I found a tick attached to me. After analyzing the insect and diagnosing the blood, I received a diagnosis of tick-borne borreliosis. It was scary, but the doctor calmed me down and prescribed several medications, including Cycloferon injections. So far I have only completed one course, there are still three left.

I get a physical every year because I work with people. At my last visit to the doctor and donation of blood, I was diagnosed with chlamydia. Before I developed an exacerbation, I decided to start urgent treatment. The therapist prescribed Cycloferon injections. Unfortunately, no changes were found during the course. You will have to either repeat it or look for a more effective medication.

Alexander, 42 years old

I have chronic viral hepatitis B, so I am a regular at hospitals. Every six months I undergo a cycle of injections with Cycloferon, which helps maintain the functioning of the immune system and liver. It’s unpleasant and expensive, but what can you do – health is more expensive. It is better to constantly monitor the condition of the body and treat it on time than to suffer.

The information presented in the article is for informational purposes only. The materials in the article do not encourage self-treatment. Only a qualified doctor can make a diagnosis and give treatment recommendations based on the individual characteristics of a particular patient.

Cycloferon, injections

Analogues and substitutes

Cycloferon is available in the form of ointment, tablets and solution for injection. There are no complete analogues with the same substance, but you can choose a substitute, see antiviral drugs, as well as immunomodulators and adaptogens.

Average price online *, 300 rub. (5 ampoules of 2 ml, 12.5%)

Instructions for use of injection

One of the effective drugs to support immunity is Cycloferon. This drug belongs to immunostimulating drugs that have antiviral and anti-inflammatory effects.

Cycloferon - instructions

Injections of Cycloferon activate the activity of stem, immune and T-lymphocyte cell structures. Cycloferon immunostimulating injections are especially effective against hepatitis, herpes, respiratory infections and the influenza virus.

The drug is characterized by low toxicity, quickly dissolves in body tissues and is eliminated naturally (through the kidneys) without consequences. Cycloferon is especially valuable in the treatment of neuroinfectious pathologies such as meningitis, encephalitis and other nervous system infections, because its components can easily pass through the blood-brain barrier.

The drug is not able to accumulate in organic tissues, has no carcinogenic properties, does not cause mutations or allergic reactions. According to research results, the injectable form of the drug is able to maintain a high interferon level for 72 hours or more, even without the use of the drug. Cycloferon can be combined with medications of other effects such as antibiotics, vitamins, immune-strengthening agents, etc.

Is this an antibiotic or not?

No, the drug is sometimes prescribed for bacterial infections, but its mechanism of action is not the same as that of antibiotics.

Indications

The injection form of the drug Cycloferon is used in the treatment of pathological conditions such as:

• Human immunodeficiency virus (HIV);
• Hepatitis of viral origin of various forms (D, B, C, A);
• Nervous system infectious processes such as tick-borne borreliosis, encephalitis or meningitis;
• Cytomegalovirus infection;
• Herpesvirus lesions;
• Chlamydial infections;
• Secondary immunodeficiencies;
• Degenerative-dystrophic joint pathologies (for example, deforming osteoarthritis, etc.);
• Systemic and rheumatic connective tissue diseases (lupus, rheumatoid arthritis, etc.).

Cycloferon is prescribed for frequent, chronic, recurrent colds, when there is immunodeficiency with unclear causes. Prescribing Cycloferon to people with normal immunity can cause autoimmune diseases.

Application for the prevention of various diseases:

Likewise, only as prescribed by a doctor.

Directions for use, dosage

The use of Cycloferon injections requires strict adherence to the instructions. General therapy is prescribed in accordance with the underlying pathology, but Cycloferon is administered to patients according to a specific scheme:

1. First, on the 1st and second day of treatment;
2. Then on days 4, 6 and 8 of the course;
3. Then at 11 and 14, 17 and 20, 23 and 26, 29 days of treatment.

Ampoules with solution must be opened immediately before administration. Injections are administered intramuscularly or intravenously, first once a day, and then according to the above scheme. Typically, immunomodulatory therapy with Cycloferon lasts about a day. If necessary, a repeat course of treatment is prescribed. It is recommended to combine Cycloferon therapy with antibacterial drugs.

In pediatrics, Cycloferon is also used quite actively. The drug is administered to children in accordance with their body weight (approximately 6-10 mg of medication per 1 kg of child weight). A more specific treatment regimen is prescribed directly by the doctor.

Contraindications

The attached instructions indicate that Cycloferon injections are contraindicated:

• In the presence of increased hypersensitivity to the drug;
• Children under 4 years of age;
• Patients with hepatic cirrhosis at a decompensated stage of development;
• Pregnant and lactating women.

Cycloferon should be taken with some caution by persons suffering from acute digestive pathologies such as erosive or ulcerative processes in the duodenum or gastric tissues, duodenitis and gastritis. In addition, caution should be exercised when treating Cycloferon in patients prone to allergies.

Pregnancy and lactation

According to experts and the instructions for the drug, the use of such a medicine is contraindicated during pregnancy or lactation.

Alcohol compatibility

The official instructions do not contain information about the interaction of cycloferon with alcohol, but:

• Cycloferon is prescribed when the patient’s body is weakened by viruses or any infection. Drinking alcohol only worsens this condition, helping viruses spread throughout the body.

Overdose

There are no data on reported cases of overdose.

Side effects

Among the possible side effects, experts identify allergic reactions. However, such a reaction is quite rare and mainly in patients prone to allergies or hypersensitive to Cycloferon.

The drug does not affect the reaction rate, so it cannot impair the ability to drive vehicles or operate machinery.

Composition and pharmacokinetics

Cycloferon injection solution consists of:

The active substance of the drug belongs to low-molecular interferon inducers, and therefore has a fairly wide spectrum of bioactivity.

After administration of the injection solution, the maximum level of the drug in the blood is observed after one and a half to two hours. After a day, it is contained in the body in trace quantities. The half-life of Cycloferon takes about 4-5 hours. With long-term therapy, the drug does not accumulate in organic structures.

Other

Cycloferon ampoules are suitable for use for 3 years from the date of production. The drug belongs to list B; it does not change its therapeutic properties when frozen.

Ampoules should be stored in a place inaccessible to children and protected from light exposure. The drug is sold from pharmacies only with a doctor's prescription.

If a precipitate appears in the ampoules with the solution or the color of the drug changes, then the use of such a medicine is unacceptable. Normally, the drug is a transparent yellowish liquid without any impurities.

Reviews

(Leave your feedback in the comments)

* - Average value among several sellers at the time of monitoring, is not a public offer

37 comments

Unfortunately I have side effects from this drug.

Maria, what are your side effects? In any case, it is better to consult a doctor or the manufacturer through the website. I know that manufacturers collect reviews of drugs; if something goes wrong, this is important both for them and for us.

I take cycloferon for colds, it helps very well. I recover in a few days, easily and quickly. If I manage to take it at the first sign of illness, I don’t get sick at all.

after the injection it hurts like crazy for about 15 minutes

Today I received my first injection of this drug. I’m sick, I’m lying in bed, my head is heavy. I hope the discomfort will go away soon. The gynecologist prescribed 10 injections

This is my fourth injection, but there is no pain at all, only pain during the puncture. I even began to doubt the authenticity of the medicine.

I also have no pain depending on how I inject. You need to slowly inject the medicine, for example, I inject vitamins b6 b12, it doesn’t hurt either, although many say that the injection is painful

Does cycloferon help with chronic urticaria, a dermatologist prescribed it to me

Usually no, maybe your doctor is not telling you something.

Is it possible to dilute: an ampoule of cycloferon is diluted in 1 liter. water and drink three sips three times a day....to boost immunity?

No, it is not digested that way and can have a bad effect on the stomach.

Hello! They can’t do victrorectectomy on my eye because there is swelling. Inflammation. I got tested for everything. The immunogram was discovered on the market by a simple hero, cytomegalovirus g, but infectious disease specialists say that this cannot be treated, and in the higher anatations for cycloferon I read that it can be used. Tell me yes or no what to take then. Thank you

Unfortunately, cytomegalovirus cannot be cured, just like many other viruses, this is true. At the beginning of the disease, the symptoms are most pronounced, then gradually fade away as immunity develops. Sometimes doctors prescribe antiviral drugs, but their effect on CMV is questionable.

Is CYCLOFERON suitable for the treatment or prevention of pityriasis versicolor?

No, start with antifungal ointment.

Hello, Cycloferon, will it help with dizziness?

You cannot cure dizziness on your own. You need to contact a neurologist and follow his instructions.

Hello, will Cycloferon help me with dizziness?

I give injections of cycloferon. Is it possible to take duspatalin at the same time? Are these drugs compatible?

Is it possible to inject the drug for molluscum contagiosum?

It is possible, but there is no guarantee that recovery will be faster.

I have been taking a course of cycloferon consisting of 10 ampoules for the fourth or fifth year in a row. Sometimes even twice a year, every 6 months. I always start the course with the transition to “winter time”, that is, November 1st. I want to say that I began to endure winter better, and I got rid of herpes rashes on my lips. So I recommend it to everyone. Especially for those who like to travel, who, like me, go to warm countries for a couple of weeks in the middle of winter. Previously, upon returning home, I would go on sick leave, blaming it on a cold due to climate change. Now there is no such problem, no fever, no sore throat, no long-term cough, and no herpes on the lips!

Hello. Please tell me how to administer cycloferon intravenously? just one ampoule or mix it with NaCl?

There is no need to mix anything, put it intramuscularly. The drug is placed into a vein with a dropper; after all, it is an acid.

Good night, is it necessary to inject it for trichomoniasis?

In some cases, the doctor may prescribe it in addition to the main treatment. There is no need to prescribe on your own.

Hello, please tell me, the doctor prescribed me cycloferon 2.0 every day for 10 days, but I can still inject it

Hello! I have herpes on my lips and papillomas, and chronic inflammation of the ovaries, can’t I do it without a prescription?

Maybe they will sell it without a prescription, although now they are stricter about this.

I started having an allergy after taking the 3rd injection

Tell me, how should I use it for rheumatoid polyarthritis?

There is no easy answer here. Your doctor may prescribe the drug under certain conditions. Then he will determine the dosage and duration.

Hello! The doctor prescribed 10 ampoules of cycloferon 2.0, but every other day. Can I inject every day?! Or strictly for its intended purpose?!

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Pharmacological properties

CYCLOFERON is a low-molecular-weight interferon inducer, which determines a wide range of its biological activity (antiviral, immunomodulatory, anti-inflammatory, etc.).
The main interferon-producing cells after administration of CYCLOFERON are macrophages, T- and B-lymphocytes. Depending on the type of infection, the activity of one or another part of the immune system predominates. The drug induces high titers of interferon in organs and tissues containing lymphoid elements (spleen, liver, lungs), activates bone marrow stem cells, stimulating the formation of granulocytes. CYCLOFERON activates T-lymphocytes and natural killer cells, normalizes the balance between subpopulations of T-helpers and T-suppressors. Enhances the activity of α-interferons.
CYCLOFERON is effective against tick-borne encephalitis viruses, influenza, hepatitis, herpes, cytomegalovirus, human immunodeficiency virus, papilloma virus and other viruses.
In acute viral hepatitis, CYCLOFERON prevents the disease from becoming chronic.
At the stage of primary manifestations of HIV infection, it helps to stabilize immunity levels.
The drug has been found to be highly effective in the complex treatment of acute and chronic bacterial infections (neuroinfections, chlamydia, bronchitis, pneumonia, postoperative complications, urogenital infections, peptic ulcers) as a component of immunotherapy. CYCLOFERON is highly effective in treating rheumatic and systemic connective tissue diseases, suppressing autoimmune reactions and providing anti-inflammatory and analgesic effects.

Pharmacokinetics.

When the maximum permissible dose is administered, the maximum concentration in the blood is reached after 1-2 hours; after 24 hours the drug is detected in trace amounts. Crosses the blood-brain barrier. The half-life is 4-5 hours. Does not accumulate in the body with prolonged use.

Indications for use

In adults in complex therapy:

HIV infection (stages 2A - 2B);

Neuroinfections: serous meningitis and encephalitis, tick-borne borelliosis (Lyme disease);

herpes and cytomegalovirus infection;
secondary immunodeficiencies associated with acute and chronic bacterial and fungal infections;
chlamydial infections;
rheumatic and systemic connective tissue diseases (rheumatoid arthritis, systemic lupus erythematosus);
degenerative-dystrophic diseases of the joints: deforming osteoarthritis, etc.
In children in complex therapy:

Viral hepatitis A, B, C, D;

Herpetic infection;
HIV infection (stages 2A-2B);
Contraindications
Pregnancy, lactation, hypersensitivity to the components of the drug, decompensated cirrhosis of the liver, children under 4 years of age.

Directions for use

1. In adults:

CYCLOFERON is used intramuscularly or intravenously once a day according to the basic regimen: every other day. The duration of treatment depends on the disease.

1.1 For herpes and cytomegalovirus infection, according to the basic regimen, 10 injections of 0.25 g each. Total dose 2.5 g. Treatment is most effective at the beginning of an exacerbation of the disease.

1.2 For neuroinfections, the drug is administered according to the basic regimen. The course of treatment is 12 injections of 0.25-0.5 g in combination with etiotropic therapy. Total dose 3-6 g. Repeated courses as needed.

1.3 For chlamydial infection, administer according to the basic regimen. The course of treatment is 10 injections of 0.25 g. Total dose is 2.5 g. Repeated course of treatment after 10-14 days. It is advisable to combine CYCLOFERON with antibiotics.

1.4 For acute viral hepatitis A, B, C, D and mixed forms, the drug is administered according to the basic scheme of 10 injections of 0.5 g. The total dose is 5.0 g. In case of protracted infection, repeat the course after 10-14 days.
For chronic viral hepatitis B, C, D and mixed forms, the drug is administered according to a basic regimen of 10 injections of 0.5 g each, then according to a maintenance regimen 3 times a week for three months as part of complex therapy. Recommended in combination with interferons and chemotherapy. Repeat the course after 10 – 14 days.

1.5 For HIV infection (2A-2B), according to the basic regimen, 10 injections of 0.5 g each and then according to the maintenance regimen once every three days for 2.5 months. Repeat the course after 10 days.

1.6 For immunodeficiency conditions, the course of treatment is 10 intramuscular injections according to the basic regimen in a single dose of 0.25 g. The total dose is 2.5 g. A repeated course is carried out after 6 - 12 months.

1.7 For rheumatic and systemic diseases of connective tissue, 4 courses of 5 injections according to the basic regimen of 0.25 g with a break of 10-14 days. Repeated course on doctor's recommendation.

1.8 For degenerative-dystrophic diseases of the joints, 2 courses of 5 injections of 0.25 g each with a break of 10-14 days according to the basic scheme. Repeated course on doctor's recommendation.

2. In children:

In pediatric practice, CYCLOFERON is used intramuscularly or intravenously once a day according to the basic regimen: every other day. The daily therapeutic dose is 6-10 mg/kg body weight.

2.1 For acute viral hepatitis A, B, C, D and mixed forms, the drug is administered according to the basic scheme of 15 injections. In case of prolonged infection, repeat the course after 10-14 days.

2.2 For chronic viral hepatitis B, C, D, the drug is administered according to a basic regimen of 10 injections and then according to a maintenance regimen three times a week for three months as part of complex therapy. Recommended in combination with interferons and chemotherapy.

2.3 For HIV infection (stages 2A-2B), a course of 10 injections according to the basic regimen and then according to the maintenance regimen once every three days for three months. Repeat course after 10 days.

2.4 For herpes infection, a course of 10 injections according to the basic regimen. If the replicative activity of the virus remains, the course of treatment is continued according to a maintenance regimen with administration once every three days for four weeks.

Side effect

Allergic reactions.

Overdose

There is no information about an overdose of the drug.

Interaction with other drugs
CYCLOFERON is compatible and goes well with all drugs traditionally used in the treatment of these diseases (interferons, chemotherapeutic drugs, etc.). Enhances the effect of interferons and nucleoside analogues. Reduces the side effects of chemotherapy, interferon therapy.

Special instructions

CYCLOFERON does not affect the ability to drive vehicles.
When treating influenza and respiratory viral infections, symptomatic therapy is carried out.
For diseases of the thyroid gland, consultation with an endocrinologist is necessary.

Best before date

5 years. After the expiration date, the use of the drug is not allowed.

Conditions for dispensing from pharmacies

According to the recipe.

Is a medicine. A doctor's consultation is required.

The basis of good health and the body's immunity to infections and foreign substances for humans is the presence of a strong immune system. But sometimes it can be weakened by seasonal diseases, an unhealthy lifestyle, or a diet that does not contain important and necessary nutrients. In such cases, taking vitamins sometimes becomes insufficient and immunostimulants created with the help of modern pharmacy come to the rescue. One of these “helpers” for activating the immune system is Cycloferon.

Dosage forms of Cycloferon

Cycloferon is available in several forms:

• tablets – for oral use;
• ointment – ​​for local external application;
• injections – used to inject a drug into a muscle or vein.

Cycloferon in ampoules can be produced:

1. In the form of a lyophilisate - a dry substance of Cycloferon, which has undergone a soft drying process in a vacuum apparatus. The lyophilisate is used for long-term storage and, for injections, is pre-diluted with a special liquid.
2. In the form of ready-made injections that do not require additional dilution - this form of release is convenient for independent use at home, if you have medical experience.

Diseases for which Cycloferon is used in ampoules

Cycloferon is prescribed to enhance the activity of the immune system in the complex treatment of colds, flu and during exacerbation of seasonal diseases (autumn-spring). Also, indications for the use of Cycloferon injections are the following diseases:

• human immunodeficiency virus (stages 2A-2B);
• hepatitis;
• herpes;
• the presence of chlamydia and CMV - infection;
• secondary immunodeficiencies;
• neuroinfections;
• acute intestinal infections;
• rheumatic and

Side effects of Cycloferon

Since Cycloferon belongs to the pharmacological group of interferons, i.e. In essence, it is a protein synthesized by the human body in response to the invasion of a virus and preventing its development; no side effects of this drug have been noted. The only undesirable effect of taking Cycloferon may be individual intolerance to it by the body, manifested by allergic reactions.

Barriers to the use of Cycloferon

The drug is not allowed for use during pregnancy and lactating women, as well as for children under four years of age.

Cycloferon is used with caution when diagnosing liver cirrhosis. If there are problems associated with the endocrine system, the use of the drug requires constant monitoring by a specialist doctor (endocrinologist).

How to inject Cycloferon in ampoules?

To activate the immune system in case of “mild” diseases (flu), Cycloferon injections are made intramuscularly according to the basic scheme: 0.25-0.5 g once a day for two days in a row and then switch to injections every other day.

It should be noted that, for various diseases, the optimal treatment regimen with Cycloferon in ampoules is established by the attending physician, based on the severity of the disease, general indicators of the body and the main treatment.

Approximate injection schedules for Cycloferon:

1. Herpes. Injections are given according to the basic scheme indicated above. The total number of injections is ten, then a break is taken for 14 days and another course of 7 injections is given.
2. Hepatitis. For acute forms, the basic regimen is used, 6 grams per course. In the chronic form of the disease, as maintenance therapy, 0.25 g (one ampoule) once every five days for three months.
3. Neuroviral infections. The main regimen is 0.6 g of the drug, then maintenance therapy is also 0.6 g every five days, for 2.5-3 months.

There are a lot of drugs that help get rid of the same problem. Now I would like to talk about such a medicine as Cycloferon: instructions for use. Injections and tablets - all forms of this medication will be discussed further.

Basic information about this medicine

The drug "Cycloferon" has a very wide spectrum of action. So, it is an antiviral, anti-inflammatory and immunomodulatory drug.

This drug also has an antitumor and antiproliferative effect, that is, it fights the proliferation of various cells.

After administration, the amount of interferons increases in the human body, namely in the spleen, lungs, liver, and intestinal mucosa. At the same time, the drug also activates brain stem cells and corrects the immune status, increasing the body's defenses.

Indications for use of the drug

In what situations can doctors prescribe this medication?

• For herpetic or cytomegalovirus infection.
• For various respiratory diseases, flu.
• For various infections: intestinal, neuroinfections.
• In the case when bacterial or fungal infections lead to immunodeficiency.
• For chronic hepatitis, as well as HIV infections.
• With chlamydia.
• For diseases of the joints of a degenerative-dystrophic nature.

This medicine can also be used in the treatment of children. In this case, it is prescribed as part of complex therapy for children whose age exceeds 4 years. It is used for viral hepatitis, herpes infection and HIV infection.

The drug "Cycloferon": instructions for use (injections)

Having figured out in what cases this drug can be prescribed, you also need to tell how it should be used correctly. What do you need to know before using the drug "Cycloferon"?

The instructions for using injections read as follows: the medicine is administered intramuscularly or intravenously once a day. There is also a basic regimen for administering the drug, but it can be adjusted depending on the disease and the prescription of the treating doctor.

Basic scheme. The drug is administered not daily, but on the following days, starting from the first day of treatment and then on the 2nd, 4, 6, 8, 11, 14, 17, 20, 23, 26, 29th day. The dosage may vary depending on the disease:

• For viral hepatitis, the amount of medication should not exceed 250-500 mg. The course will require 10 injections. Treatment can be repeated after 10-14 days.
• For herpes infection: dosage – 250 mg, number of injections – 10. The drug is most effective at the beginning of the disease.
• For chlamydia, a single dose is 500 mg once a day. The total number is also 10 injections. A repeat course is usually prescribed after a month. Before this, maintenance medications are taken.
• For immunodeficiency, the course is also a ten-time administration of the drug, once a day. A second course of therapy can be carried out after half a year or even after a year.

For other diseases (for example, HIV infection), the dosage is individual and determined by the treating doctor.

"Cycloferon": tablets. Instructions for use of the drug

Having considered how to take - intravenously or intramuscularly - the drug "Cycloferon", tablets - instructions for using the medicine in this form - this must also be discussed.

Generally speaking, a tablet is taken once per day, half an hour before meals. The pill should be washed down well with water, without chewing. The dosage will depend on the disease that the patient is trying to cope with.

1. For herpes infection, you need to take 2-4 tablets according to the basic regimen (described above). It is best to start treatment at the time of exacerbation of the disease.
2. For acute respiratory infections and flu, the dosage is the same - 2-4 pills. A full course may include from 10 to 20 tablets. The medication begins immediately after the very first symptoms appear.
3. For viral hepatitis, the medicine is taken 4 pills per day according to the basic regimen.
4. Intestinal infections can be cured by taking 2 pills as described above. The course of treatment is 20 tablets.
5. For immunodeficiency, you should take two tablets a day according to the basic regimen.

Self-medication can be harmful to your health.
You should consult your doctor and read the instructions before use.

Cycloferon: instructions for use

Compound

active substance: meglumine acridone acetate in terms of acridone acetic acid 150 mg; excipients: povidone, calcium stearate, hypromellose, polysorbate 80, methacrylic acid and ethyl acrylate copolymer (1:1), propylene glycol.

Description

Yellow biconvex tablets, enteric-coated.

Pharmacological action

Cycloferon is a low-molecular-weight interferon inductor, which determines a wide range of its biological activity (antiviral, immunomodulatory, anti-inflammatory, etc.).

Cycloferon is effective against viruses - herpes - influenza - and - other pathogens - acute respiratory diseases. It has a direct antiviral effect, suppressing viral reproduction in the early stages (1-5 days) of the infectious process, reducing the infectivity of viral offspring, leading to the formation of defective viral particles. Increases the body's nonspecific resistance to viral and bacterial infections.

Pharmacokinetics

When taking a daily dose, the maximum concentration in the blood plasma is reached after 2-3 hours, gradually decreases by the 8th hour, and after 24 hours Cycloferon is detected in trace amounts. The half-life of the drug is 4-5 hours, so using it in recommended doses does not create conditions for accumulation in the body. It is excreted unchanged by the kidneys.

In patients with impaired renal and liver function, as well as in elderly patients, no change in dosage regimen is required.

Indications for use

adults in complex therapy:

Flu and acute respiratory diseases;

Herpetic infection.

In children starting from four years of age in complex therapy:

Influenza and acute respiratory diseases;

Herpetic infection.

In children over four years of age for the prevention of influenza and acute respiratory diseases.

Contraindications

Pregnancy, breastfeeding period, children under 4 years of age (due to imperfect swallowing), individual intolerance to the components of the drug, decompensated cirrhosis of the liver.

Directions for use and doses

Orally once a day 30 minutes before meals, without chewing, with a glass of water, in age-specific dosages:

children 4-6 years old: 150 mg (1 tablet) per dose; children 7-11 years old: 300-450 mg (2-3 tablets) per dose; adults and children over 12 years of age: 450-600 mg (3-4 tablets) per dose.

It is advisable to repeat the course 2-3 weeks after the end of the first.

In adults:

1. When treating influenza and acute respiratory diseases, the drug is taken on days 1, 2, 4, 6, 8 (course of treatment - 20 tablets). Treatment should begin at the first symptoms of the disease. For severe flu, six tablets are taken on the first day. If necessary, additional symptomatic therapy is carried out (antipyretics, analgesics, expectorants). I

2. For herpes infection, the drug is taken on days 1, 2, 4, 6, 8, 2, 14, 17, 20, 23 (course j of treatment - 40 tablets). Treatment is most effective when the first symptoms of the disease appear.

In children from four years of age:

1. For influenza and acute respiratory diseases, the drug is taken in age-appropriate doses of 1, 2,"

4, 6, 8, 11, 14, 17, 20, 23 days. The course of treatment ranges from 5 to 10 doses, depending on the severity of the condition and the severity of clinical symptoms.

1. For herpes infection, the drug is taken on days 1, 2, 4, 6, 8, 2, and 14 of treatment. The course of treatment may vary depending on the severity of the condition and the severity of clinical symptoms.

2. For emergency nonspecific prevention of influenza and acute respiratory diseases (in direct contact with patients with influenza or acute respiratory infections of another etiology, during an influenza epidemic), the drug is taken on the 1st, 2nd, 4th, 6th, 8th day. Then take a break of 72 hours (three days) and continue the course for 11,! 4, 17,20, 23 days. The general course is from 5 to 10 doses.

If the next dose of the drug is missed, then you should, at the first opportunity, without taking into account the time interval and doubling the dosage, continue the course according to the started regimen.

Side effect

Allergic reactions.

Overdose

To date, no cases of overdose have been identified.

Precautions

For diseases of the digestive system in the acute stage (erosion, gastric and/or duodenal ulcers, gastritis and duodenitis) and a history of allergic reactions before taking the drug, be sure to consult your doctor.