Vikasol instructions for use in tablets. This includes such negative factors as

Instructions for use:

Vikasol belongs to the group of vitamins obtained synthetically. Vitamin K analogue.

Pharmacological action

Water-soluble analogue natural vitamin K, obtained in the laboratory. Takes part in the formation of prothrombin. Normalizes blood clotting parameters. A lack of vitamin K leads to increased bleeding.

Release form

Vikasol is produced in powder, in tablets of 0.015 g and in ampoules of 1 ml with a 1% solution.

Indications for use of Vikasol

The use of Vikasol is advisable in the following cases:

Jaundice, which develops due to untimely entry of bile into the intestines;

Capillary and parenchymal bleeding;

Bleeding that occurs with peptic ulcer stomach and duodenum;

Thrombocytopenic purpura;

Radiation sickness;

Constant nosebleeds and hemorrhoids.

According to the instructions, Vikasol is prescribed to pregnant women in the last trimester to prevent bleeding in newborns.

It is possible to use Vikasol in newborns with hemorrhagic disease (increased bleeding).

Vikasol injections and tablets are prescribed for juvenile uterine and dysfunctional uterine bleeding before puberty and in the premenopausal period.

The use of Vikasol is advisable in case of bleeding due to tuberculosis, septic diseases, decreased coagulability, the use of anticoagulants, vitamin K antagonists, phenylin, neodicoumarin and other drugs with similar effects.

Prescribing Vikasol injection solution and tablets for hemophilia and Werlhof's disease does not bring the desired therapeutic effect.

Instructions for use of Vikasol and dosage

Vikasol tablets are taken orally. The injection solution is prescribed intramuscularly. Average dose for adults: Vikasol tablets from 0.015 to 0.3 g per day; injection solution from 0.01 to 0.015 g. Maximum permissible doses for adults: Vikasol tablets at one time no more than 0.03 g, per day - no more than 0.06 g; intramuscular injection, no more than 0.015 g per injection and no more than 0.03 g per day.

Vikasol can be used for children under one year of age. In this case, acceptable daily dose ranges from 0.002 to 0.005 g. Children under three years old can take Vikasol in a dose of 0.006 grams, from 3 to 4 years old - 0.008 g, at 5-9 years old can be prescribed 0.01 g Vikasol, from 10 to 14 years old - 0.015 g. The daily dose is divided into 2 or three doses, take Vikasol according to the instructions for three or four days in a row, then take a four-day break, and repeat the course again.

The dose of Vikasol for newborns should not exceed 0.004 grams.

Women in labor are prescribed Vikasol in a daily dose for adults at one time; if labor does not occur, then the use of Vikasol is advisable after 12 and 24 hours.

Side effects

The instructions for Vikasol indicate possible side effects. These include:

Hypervitaminosis of vitamin K, resulting in an increase in prothrombin and thrombin, bilirubin;

Toxicosis in children, which manifests itself in the form of seizures.

Contraindications to the use of Vikasol

Vikasol is contraindicated in case of increased blood clotting and thromboembolism (blockage of blood vessels with blood clots).

Vikasol for menstruation

Vikasol during menstruation has the ability to reduce the amount of discharge if it is heavy. But Vikasol during menstruation does not always bring the desired effect. Therefore, it is not recommended to take Vikasol on your own during menstruation; you must undergo an examination by a gynecologist. It should be remembered that only a doctor can prescribe Vikasol.

The release form of Vikasol is tablets and ampoules for solution. The number of indications for the use of this remedy is quite large. For example, these injections are prescribed when hemorrhagic syndrome, hypovitaminosis, bleeding, uterine bleeding. Regarding pharmacological action, then participates in the formation of prothrombin.

Indications for use

All indications specified in the instructions are listed below:

• hemorrhagic syndrome, which is associated with hypoprothrombinemia;
• bleeding after injuries, wounds, surgical interventions;
• hemorrhagic disease newborns;
• overdose of vitamin K antagonists;
• hypovitaminosis K;
• with dysfunctional uterine bleeding.

Contraindications for use

The instructions for tablets and ampoules contain not only indications, but also contraindications. There are three in total: increased sensitivity to the components hemolytic disease newborns, increased blood clotting. It should be taken with caution when prescribed during pregnancy and liver failure.

Vikasol instructions for use - dosage in tablets and ampoules

Both tablets and ampoules, adults need to take 15-30 mg per day. Tablets are taken orally, and ampoules are taken intramuscularly. For newborns, the dosage should not exceed 4 mg. For older children, the amount of ml that can be taken according to instructions is also less than for adults.

Vikasol instructions for use for menstruation

During menstruation, it should be taken carefully. The main purpose for tablets and ampoules at this time is to stop menstruation. In order to stop your period, you should take two tablets per day. As for ampoules, menstruation can be stopped with one injection of Vikasol.

Vikasol instructions for use for uterine bleeding

The description of the indications states that in addition to menstruation, it can be used for uterine bleeding. For intramuscular injection the dosage is 15 mg. Injections are given twice a day.

Vikasol for newborns

Information from reviews suggests that this product and its analogues are widely used even for newborns. The permissible daily dose is about 0.002 - 0.004 g. Moreover, it can be prescribed even to women in labor.

Vikasol injections instructions for use

Intramuscular injections with a 1% solution should be 0.015 g per injection and 0.03 g per day maximum. However, injections in such doses can be prescribed for jaundice due to failure of bile to enter the intestines, for menstruation and for other indications in the instructions only for adults. For children, the dosage is much less.

Vikasol and alcohol compatibility

This remedy is one of many that is compatible with alcohol. Since this drug is an analogue of Vitamin K, it can be very useful for people who abuse alcohol.

During early pregnancy Vikasol

As for pregnancy, the drug is often prescribed in the last trimester to prevent bleeding. However, in medical practice there are enough cases when it is used for the same purpose in the first trimester.

Analogs

Bleeding during menstruation and other cases can be stopped by analogues such as Dicynon and Etamzilat. Takhacomb and Tranexam are also considered analogues.

Vikasol or Dicynon, which is better?

Dicynon beats Vikasol in terms of speed. For other indicators (decrease pain and relieving excess) these drugs are generally equal. This is confirmed by reviews from doctors. At the same time, Vikasol is much cheaper.

Menadione sodium bisulfite (menadione)

Composition and release form of the drug

30 pcs. - dark glass jars (1) - cardboard packs.
10 pcs. - contour cell packaging (3) - cardboard packs.

Pharmacological action

Antihemorrhagic agent. It is a synthetic analogue of K. It is a cofactor for the synthesis of prothrombin and other blood coagulation factors (VII, IX, X) in the liver, and helps normalize the blood coagulation process.

Pharmacokinetics

After oral administration, it is absorbed from the gastrointestinal tract. Protein binding is reversible. Accumulates mainly in the liver, spleen, and myocardium. Converts into vitamin K2 in the body. The most intensive conversion process occurs in the myocardium, skeletal muscles, somewhat weaker - in the kidneys.

Metabolites of vitamin K (monosulfate, phosphate and diglucuronide-2-methyl-1.4-naphthoquinone) are excreted in the urine - up to 70%.

Indications

Hemorrhagic syndrome associated with hypoprothrombinemia; hypovitaminosis K (including with obstructive jaundice, hepatitis, prolonged diarrhea); hemorrhagic disease of newborns; bleeding after wounds, trauma and surgery; in gynecology as part of complex treatment dysfunctional uterine bleeding not related to organic pathology, with menorrhagia. As a specific antagonist for bleeding associated with taking indirect drugs. III trimester of pregnancy (to prevent bleeding in newborns).

Contraindications

Increased blood clotting, thromboembolism, increased sensitivity to menadione.

Dosage

For adults, when taken orally - 15-30 mg/day, intramuscularly - 10-15 mg/day.

Children under 1 year old - 2-5 mg/day, up to 2 years old - 6 mg/day, 3-4 years old - 8 mg/day, 5-9 years old - 10 mg/day, 10-14 years old - 15 mg /day Frequency of administration: 2-3 times/day. The duration of treatment is determined individually.

Maximum doses: for adults when taken orally single dose- 30 mg, daily - 60 mg; with intramuscular administration, a single dose is 15 mg, a daily dose is 30 mg. For newborns - 4 mg/day.

Side effects

Allergic reactions:, itching, erythema, urticaria, bronchospasm.

Violations menstrual cycle- one of common reasons women's visits to a gynecologist. This pathology may appear different symptoms. However, the biggest concern is heavy periods, which can cause a number of complications. “Vikasol” increases blood clotting characteristics, can reduce the amount of bleeding and reduce the number of “critical” days.

The main active ingredient in Vikasol is menadione sodium bisulfite. This medicine belongs to the group of antihemorrhagic drugs and is similar in structure to vitamin K. The latter is extremely important substance, promoting the formation of blood coagulation factors: VII, IX, X. The presence of these factors is necessary to trigger the mechanism of fibrin clot formation. Vitamin K is involved in the conversion of prothrombin to thrombin, which affects the duration of bleeding.

"Vikasol" cannot be used to deliberately provoke a delay in menstruation. The drug does not change hormonal background and cannot affect the onset of menstruation.

Release forms

"Vikasol" is produced in the form of two pharmaceutical forms.

1. Pills. Contains 0.015 g of menadione sodium bisulfite. In addition, this dosage form includes fillers: sucrose, starch, calcium stearate and others.
2. Ampoules. The injections contain 1 ml of solution containing 0.01 g of menadione. This form release is intended for intramuscular administration only.

Within the space of active substance medicine is in bound state with plasma proteins. “Vikasol” penetrates well into almost all tissues of the body, especially high concentrations are found in the heart muscle, striated muscles, spleen, and liver. Most of this drug is excreted from the body in the urine.

After ingestion of the tablet form of the drug, it is rapidly absorbed into the gastrointestinal tract. Menadione acts within eight hours after entering the blood.

Indications

Indications for the use of "Vikasol" are any conditions associated with increased risk bleeding. Most often the drug is recommended for the following pathologies:

• hemorrhages caused by insufficient intake of vitamin K into the body (intestinal diseases, severe pathologies liver);
• hemorrhagic diseases in newborns;
• bleeding caused by trauma or wounds;
• uterine bleeding due to a disrupted menstrual cycle;
• heavy periods with fibroids or the onset of menopause;
• high risk bleeding while taking anticoagulants;
• nosebleeds;
• bleeding from the gastrointestinal tract;
• bleeding from hemorrhoids.

Vikasol is also prescribed to prevent bleeding in preoperative period or after the operation.

There are recommendations on the Internet about the use of menadione in veterinary medicine. In particular, to save animals in case of poisoning rat poison(inhibits vitamin K). However, the drug does not replenish the resulting vitamin K deficiency; the method itself has no scientific evidence, and it is better to use special drugs for pets.

Dosages

Tablets are taken between meals with a glass of sufficient quantity drinking water. For children infancy the drug is administered parenterally.
The dosage of the medicine is determined according to the following table.

Table - Vikasol dosage by age

The maximum amount of medication that an adult patient can take at one time is 30 mg. No more than 60 mg of Vikasol is allowed per day, divided into two or three doses. (For newborns - no more than 4 mg).

When treating heavy periods, the drug should be taken several days before the expected date of menstruation. Total time therapy - three to four days.

It is not recommended to take the drug without consulting a gynecologist. Heavy periods can be caused by organic pathology in the uterus or hormonal disorders. In this case, Vikasol will only reduce the symptoms, but will not eliminate the problem.

Side effects

In general, the medicine is well tolerated by patients, but sometimes the following are noted: side effects:

• disorders in the blood system (hemolytic anemia, hemolysis in the presence of congenital enzymopathies);
• allergy in the form skin rash, itching, peeling, spasm of bronchioles;
• vestibular disorders, weakness, taste disturbances;
• increased bilirubin levels;
• drop in blood pressure;
• rapid heartbeat.

Extremely rare when taken large doses An overdose of Vikasol may occur. It manifests itself with the following symptoms:

• increase in prothrombin index;
• increased blood bilirubin levels;
• convulsions.

Contraindications

The use of Vikasol is contraindicated in the following cases:

• individual intolerance individual components drug;
• increased blood clotting;
• tendency to thrombosis;
• disturbance of sugar metabolism;
• severe liver dysfunction.

The tablets are not recommended for children under three years of age. They should be used with caution in pregnant and lactating women. If a patient is diagnosed with diseases that lead to impaired outflow through the biliary tract, then only the injectable form of the medicine should be used.

Caution should be exercised if the following medications are already prescribed along with Vikasol:

• indirect anticoagulants;
• antibiotics wide range actions;
• quinidine;
• salicylates;
• quinine;
• sulfonamides;
• cholestyramine;
• sucralfate.

"Vikasol" is an over-the-counter medicine. Its exact analogues are on pharmaceutical market not presented. But as an alternative, the pharmacist can offer other drugs that have a hemostatic effect: “Etamzilat” (“Dicynon”) or “Tranexam” (tranexamic acid).

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Price for Vikasol tablets (15 mg, 20 pcs.): 60-90 rub.

Vikasol during pregnancy

Pregnancy is a very significant moment in a woman’s life, but this exciting and touching period does not always proceed without problems. The most common threat of spontaneous miscarriage is vaginal bleeding. In such cases, the drug Vikasol helps reduce blood loss and maintain pregnancy.

Risk factors for miscarriage

The appearance of spotting bloody discharge from the vagina during pregnancy can cause a number of reasons.

This includes such negative factors How:

• ectopic pregnancy (when a fertilized egg attaches and develops not in the uterus itself, but outside it);
• non-developing pregnancy and embryo death due to genetic abnormalities;
• failures in hormonal sphere in a pregnant woman;
• abnormal localization ovum in the uterine cavity.

Reason vaginal bleeding can also become:

• short interval between births;
• diseases reproductive organs women;
• past viral diseases;
• premature placental abruption;
• physical activity.

Vikasol during early pregnancy

The initial signs of a threatened miscarriage often appear on early stages in the form of spotting vaginal discharge, which is why expectant mother must pay special attention to changes in your body.

In this situation, to maintain and harmoniously develop pregnancy, a gynecologist may prescribe Vikasol, and also recommend psychological calm and, if possible, complete absence physical activity. This drug is a powerful hemostatic agent, so doctors can recommend it only on a personal basis after assessing the results of a coagulogram test (blood clotting process). For the most effective result Vikasol is used as an injection.

Pharmacological actions of Vikasol

Vikasol is a medicine that is a vitamin synthetic origin with properties similar to vitamin K. This drug contains active substances that help prevent bleeding. The medicine supports the synthesis of prothrombin and helps normalize blood clotting.

Features of the use of the drug

It should be remembered that only a doctor can accurately determine the cause of spotting and prevent the occurrence of complications in time. Therefore, under no circumstances should a pregnant woman self-medicate or try to stop the bleeding on her own.

When using the drug, the effect active substance begins only 12 hours after administration. Vikasol accumulates in the body and is converted into vitamin K. The great advantage of the drug is that it does not negatively affect the course of pregnancy and does not harm the fetus. Vikasol is often used in combination with No-Shpa and vitamin E. No-Shpa is the best antispasmodic, and vitamin E is a single drug that has a number of properties that contribute to the harmonious development of pregnancy.

Correct use of the hemostatic agent Vikasol

Vikasol is available in the form of tablets and solution for injection in ampoules. In tablet form, the daily dose of the drug should not exceed two tablets with an interval of 12 hours for 3-4 days. Next, you need to take a break and then continue the course of therapy. The drug in tablet form is convenient for treatment not only in a hospital setting, but also at home. Special attention It is worth noting that Vikasol is contraindicated for people with increased coagulability blood and with a high risk of thromboembolism (blockage of blood vessels with blood clots).

To prevent uterine bleeding, which may occur during initial stage labor activity in women, Vikasol can be prescribed by a doctor during the first contractions.

Prevention during pregnancy

As a rule, greatest number miscarriages occur in the first trimester of pregnancy. If we're talking about about spontaneous abortion in the early stages of pregnancy, then in such cases it often occurs chromosomal abnormalities fetus To stop uterine bleeding doctors prescribe the use of Vikasol and other medicines, aimed at maintaining the integrity of the walls of blood vessels, as well as preventing and stopping bleeding. Uncontrolled and long-term use drug. The medication should only be taken under medical supervision. In most cases, two days are enough for doctors to evaluate the effectiveness of the application.

Contraindications

Contraindications to the use of Vikasol are:

• blood hypercoagulation;
• thromboembolism;
• liver diseases;
• hypersensitivity to the components of the drug.

Therefore, taking the medicine yourself, without a prescription from a specialist, is strictly prohibited.